A fluorescent immunochromatographic kit

Abstract

The utility model discloses a fluorescent immunoassay kit belongs to the in-vitro diagnosis technical field. The kit includes the base, the upper cover of lid in the base and the test paper of setting in the inside of base. Its characterized in that, the kit still includes the dirt-proof cover plate, the first magnet is fixed on the upper cover, the inboard of dirt-proof cover plate is fixed with the sealing rubber strip, and the second magnet is fixed on the dirt-proof cover plate, and the dirt-proof cover plate can be installed on the upper cover through the magnetic adsorption of the first magnet and the second magnet, and forms the sealed cooperation with the upper cover through the sealing rubber strip. The utility model solves the problem that the reagent kit reaction area is easy to be contaminated, the sealing property is not good, the internal test paper is not fixed stably and is easy to slide in the existing technology. Through the magnetic attraction type sealing cover plate effective sealing, prevent the pollution, through multiple fixed structure ensure that the test paper position is stable, and through the antiskid rubber strip enhancement places stability, ensure the accuracy of detection result and the reliability of operation.

Description

Technical Field

[0001] This utility model relates to the field of in vitro diagnostic technology, and in particular to a fluorescence immunochromatographic reagent kit. Background Technology

[0002] Fluorescent immunochromatography technology has been widely used in the field of in vitro diagnostics due to its high sensitivity and specificity, and related fluorescent immunochromatographic reagent kits are key carriers for achieving rapid detection.

[0003] Existing fluorescence immunochromatographic kits typically consist of a test strip for carrying the reaction and a housing for containing the test strip. During the test, the operator needs to add the sample to be tested onto the sample application area of ​​the test strip, where the sample undergoes a chromatographic reaction. However, during the incubation or waiting period after sample application and before the sample is placed in the fluorescence detection instrument to read the results, the sample application area of ​​the test strip or the observation area for instrument reading is often exposed or partially exposed.

[0004] This exposure makes the kits highly susceptible to contamination from dust, aerosols, or other pollutants in the external environment. Once these contaminants land in the detection or sample application area, they can not only contaminate the sample but also interfere with the reading of fluorescence signals. This is especially problematic in highly sensitive fluorescence detection, where even minor contamination can lead to inaccurate results or false positives, severely impacting the accuracy and reliability of the test results. While some kits come with simple caps, these caps typically only provide a basic physical barrier with poor sealing, failing to effectively prevent the intrusion of minute contaminants and aerosols.

[0005] Therefore, this invention proposes a fluorescence immunochromatographic reagent kit to address the shortcomings of existing technologies. Utility Model Content

[0006] In view of the problems in existing fluorescent immunochromatographic reagent kits, such as the reaction area being susceptible to external environmental contamination and poor sealing, which affects the accuracy of detection results, this utility model aims to provide a fluorescent immunochromatographic reagent kit with an improved structure that can effectively solve the above problems.

[0007] This invention provides a fluorescence immunochromatographic reagent kit, comprising: a base, a top cover removably fitted onto the base, test strips disposed inside the base, and a stain-proof cover.

[0008] The upper cover is fixed with a first magnet.

[0009] Furthermore, a sealing strip is fixed to the inner side of the anti-fouling cover, and a second magnet is fixed to the anti-fouling cover.

[0010] The anti-fouling cover is detachably mounted on the upper cover by the magnetic attraction of the first magnet and the second magnet, and forms a sealed fit with the upper cover via the sealing strip.

[0011] Preferably, a pressure strip and a pressure rod are fixedly connected to the inner surface of the top cover facing the base, and the pressure strip and the pressure rod abut against the upper surface of the test paper.

[0012] Preferably, the base is further provided with a baffle, which abuts against the side edge of the test strip.

[0013] Preferably, the kit further includes an absorbent pad connected to one end of the test strip.

[0014] Preferably, the outer bottom of the base is fixedly connected with an anti-slip rubber strip.

[0015] Preferably, the upper cover has an observation area, and the anti-fouling cover covers the observation area when closed.

[0016] Preferably, the test strip has a sample application area, and the anti-fouling cover covers the sample application area when closed.

[0017] Preferably, the test strip has a sample application area, and the anti-fouling cover also covers the sample application area when closed.

[0018] This utility model has the following beneficial effects: 1. In this utility model, by setting a dirt-proof cover and utilizing the magnetic attraction of the first magnet and the second magnet, as well as the cooperation of the sealing strip, the problem that the sample application area or detection area of ​​the reagent kit is easily contaminated by external dust, aerosols, etc., or that the sample is easily leaked is solved. The technical effect of effectively sealing the detection area, preventing contamination, and ensuring the accuracy of the detection results is achieved.

[0019] 2. In this utility model, by setting a pressure strip and a pressure rod on the inner side of the top cover and setting a baffle inside the base, the problem that the test strip is prone to loosening or displacement in the base in the prior art, resulting in abnormal chromatography, is solved. The technical effect of fixing and limiting the test strip from the top and the side is achieved, ensuring the stability of the test strip position and the reliability of the chromatography effect. Attached Figure Description

[0020] Figure 1 This is a three-dimensional schematic diagram of a fluorescence immunochromatographic reagent kit proposed in this utility model; Figure 2 This is a schematic diagram of the anti-fouling cover of a fluorescence immunochromatographic reagent kit proposed in this utility model; Figure 3This is a schematic diagram of the base of a fluorescence immunochromatographic reagent kit proposed in this utility model.

[0021] Legend: 1. Base; 2. Top cover; 3. Anti-fouling cover; 4. First magnet; 5. Sealing strip; 6. Second magnet; 7. Test paper; 8. Absorbent pad; 9. Baffle; 10. Anti-slip strip; 11. Pressure strip; 12. Pressure rod. Detailed Implementation

[0022] To make the objectives, technical solutions, and advantages of this utility model clearer, the technical solutions in the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of this utility model, and not all of them. All other embodiments obtained by those skilled in the art based on the embodiments of this utility model without creative effort are within the scope of protection of this utility model.

[0023] Example: Please refer to Figures 1 to 3 This utility model provides a fluorescence immunochromatographic reagent kit, which aims to solve the problems in the prior art where the test strip 7 of the fluorescence immunochromatographic reagent kit is easily contaminated, internally unstable, and prone to sliding during placement, leading to abnormal chromatography.

[0024] like Figure 1 , Figure 2 and Figure 3 As shown, the fluorescence immunochromatographic reagent kit includes a base 1 and a top cover 2 that is detachably fitted onto the base 1. The test strip 7 is disposed inside the base 1. The reagent kit also includes a contamination-proof cover 3. A first magnet 4 is fixed on the top cover 2. A sealing strip 5 is fixed on the inner side of the contamination-proof cover 3, and a second magnet 6 is fixed on the contamination-proof cover 3. The contamination-proof cover 3 can be opened and closed on the top cover 2 by the magnetic attraction force of the first magnet 4 and the second magnet 6, and forms a sealed fit with the top cover 2 through the sealing strip 5.

[0025] To solve the above-mentioned technical problems, the core of the technical solution of this embodiment is that the fluorescence immunochromatographic reagent kit also includes a pressure strip 11, and the pressure strip 11 forms a specific structural fit and connection relationship with the aforementioned top cover 2 and test strip 7.

[0026] Please refer to the following carefully. Figure 1 and Figure 3 The core structure is described in detail below: the pressure strip 11 has a slender strip-shaped structure.

[0027] The pressure strip 11 is fixedly connected to the inner surface of the upper cover 2 facing the base 1, and its function is to provide auxiliary fixation for the test paper 7 when the cover is closed.

[0028] At the same time, a pressure rod 12 is also fixedly connected to the inner surface of the top cover 2, and the pressure rod 12 also abuts against the upper surface of the test paper 7.

[0029] In the assembled state, the upper surface of the test strip 7 is abutted by the pressure strip 11 and the pressure rod 12.

[0030] This top clamping structure, formed by the pressure strip 11 and the pressure rod 12, ensures that the upper part of the test paper 7 is stably fixed.

[0031] For other auxiliary components used to achieve complete fixation and stability, this embodiment also includes a baffle 9 disposed inside the base 1, the baffle 9 abutting against the side edge of the test strip 7 to provide a limit; it also includes an absorbent pad 8 connected to one end of the test strip 7; and an anti-slip strip 10 fixedly connected to the bottom of the base 1 to enhance placement stability.

[0032] Based on the above embodiments, the present invention may further include the following preferred technical solutions: As a preferred embodiment, to enhance the fixation effect on the test strip 7, please refer to... Figure 1 A pressure strip 11 and a pressure rod 12 are fixedly connected to the inner surface of the top cover 2 facing the base 1. The pressure strip 11 and the pressure rod 12 abut against the upper surface of the test paper 7 when the cover is closed, and the test paper 7 is fixed by applying pressure from the top.

[0033] As another preferred embodiment, in order to achieve lateral restraint of the test strip 7, please refer to... Figure 3 The base 1 is also equipped with a baffle 9 inside, which abuts against the side edge of the test strip 7 to prevent the test strip 7 from shifting laterally.

[0034] As another preferred embodiment, to absorb excess sample liquid, please refer to... Figure 3 The kit also includes an absorbent pad 8, which is attached to one end of the test strip 7.

[0035] As another preferred embodiment, to improve placement stability, please refer to... Figure 3 The bottom of the base 1 is fixedly connected with an anti-slip rubber strip 10.

[0036] As another preferred embodiment, in order to protect the detection result area, an observation area is provided on the upper cover 2, and the anti-fouling cover 3 covers the observation area when the cover is closed.

[0037] As another preferred embodiment, in order to protect the sample application area, the test strip 7 has a sample application area, and the anti-fouling cover 3 covers the sample application area when it is closed.

[0038] As another preferred embodiment, in order to achieve simultaneous protection of the sample application area and the observation area, the test strip 7 has a sample application area, and the anti-fouling cover 3 also covers the sample application area when it is closed, that is, the anti-fouling cover 3 covers both the observation area and the sample application area at the same time.

[0039] Working principle: When in use, place the base 1 on the workbench. The anti-slip rubber strip 10 on the bottom of the base 1 contacts the workbench, which plays a role in anti-slip and stability. The operator opens the anti-fouling cover 3 that can be opened and closed and installed on the top cover 2. At this time, the sample application area on the test strip 7 or the observation area on the top cover 2 is exposed.

[0040] The sample is added to the sample application area of ​​the test strip 7, and the sample undergoes an immunochromatographic reaction on the test strip 7. Excess liquid is absorbed by the absorbent pad 8 connected to one end of the test strip 7.

[0041] After the reaction begins or the sample is added, the anti-fouling cover 3 is closed. At this time, the second magnet 6 on the anti-fouling cover 3 and the first magnet 4 on the upper cover 2 are automatically attracted by magnetic attraction. This attraction force causes the sealing strip 5 on the inner side of the anti-fouling cover 3 to be pressed tightly and form a sealed fit with the upper cover 2, thereby covering the sample addition area of ​​the test paper 7 and the observation area of ​​the upper cover 2 to prevent contaminants from entering or the sample from leaking.

[0042] Throughout the process, the upper cover 2 is detachably fitted onto the base 1. The pressure strip 11 and pressure rod 12, which are fixedly connected to the inner surface of the upper cover 2, abut against the upper surface of the test strip 7. At the same time, the baffle 9 inside the base 1 abuts against the side edge of the test strip 7. This fit ensures that the test strip 7 is stable in position during chromatography and reading and will not be displaced.

[0043] Through the synergistic sealing effect of the anti-fouling cover 3, the first magnet 4, the sealing strip 5 and the second magnet 6, as well as the synergistic fixing and stabilizing effect of the baffle 9, the anti-slip strip 10, the pressure strip 11 and the pressure rod 12, this utility model effectively solves the problems of reagent kits being easily contaminated and test strips being unstable and slippery in the prior art.

[0044] The above description is merely a specific embodiment of this utility model, but the protection scope of this utility model is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in this utility model should be included within the protection scope of this utility model. Therefore, the protection scope of this utility model should be determined by the protection scope of the claims.

Claims

1. A fluorescence immunochromatographic assay kit, comprising: Base (1); The upper cover (2) is detachably fitted onto the base (1); Test strip (7), the test strip (7) is disposed inside the base (1); Its features are, The kit also includes a dirt-proof cover (3); The upper cover (2) is fixed with a first magnet (4); A sealing strip (5) is fixed on the inner side of the anti-fouling cover (3), and a second magnet (6) is fixed on the anti-fouling cover (3). The anti-fouling cover (3) is installed on the upper cover (2) in an openable and closable manner by the magnetic attraction force of the first magnet (4) and the second magnet (6), and forms a sealed fit with the upper cover (2) through the sealing strip (5).

2. The fluorescence immunochromatographic reagent kit according to claim 1, characterized in that, A pressure strip (11) and a pressure rod (12) are fixedly connected to the inner surface of the top cover (2) facing the base (1), and the pressure strip (11) and the pressure rod (12) abut against the upper surface of the test paper (7).

3. The fluorescence immunochromatographic reagent kit according to claim 1, characterized in that, The base (1) is also provided with a baffle (9) inside, which abuts against the side edge of the test paper (7).

4. The fluorescence immunochromatographic reagent kit according to claim 1, characterized in that, The kit also includes an absorbent pad (8) which is attached to one end of the test strip (7).

5. The fluorescence immunochromatographic reagent kit according to claim 1, characterized in that, The base (1) is fixedly connected to an anti-slip rubber strip (10) on its outer bottom.

6. The fluorescence immunochromatographic reagent kit according to claim 1, characterized in that, An observation area is provided on the upper cover (2), and the anti-fouling cover (3) covers the observation area when it is closed.

7. The fluorescence immunochromatographic reagent kit according to claim 1, characterized in that, The test strip (7) has a sample application area, and the anti-fouling cover (3) covers the sample application area when closed.

8. The fluorescence immunochromatographic reagent kit according to claim 6, characterized in that, The test strip (7) has a sample application area, and the anti-fouling cover (3) also covers the sample application area when it is closed.

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