Disposable bioreactor bag with temperature measurement

Abstract

The utility model discloses a disposable biological reaction bag of temperature measurement, including bag body and temperature measuring device, temperature measuring device includes the installation fixing spare sealed connection with bag body, and the fixed plate and sensor of installation fixing spare swing joint, be equipped with the recess on the fixed plate, the recess is adapted with sensor, when the fixed plate is connected with installation fixing spare, and the recess is equipped with one side of fixed plate and is towards bag body. The utility model discloses disposable biological reaction bag of temperature measurement utilizes the detachable connecting structure of installation fixing spare and fixed plate, has realized the detachable connection between sensor and bag body, and after connecting, sensor is close to bag body, and the relative position between both is stable, namely sensor can real -time and accurate to the temperature measurement of liquid in bag.

Description

Technical Field

[0001] This utility model relates to disposable bioreactor bags, and more particularly to a disposable bioreactor bag capable of temperature measurement. Background Technology

[0002] Disposable bioreactor bags are used in various fields. When disposable bioreactor bags are used in swaying bioreactors, the sensor position is difficult to fix because the entire bioreactor is constantly swaying (wave-like) and therefore it is difficult to measure the temperature of the disposable bioreactor bag. Furthermore, since disposable bioreactor bags used in swaying bioreactors are mostly soft film bags, it is also difficult to set up rigid structures such as grooves on the disposable bioreactor bag to fix the position of the sensor. Utility Model Content

[0003] To address the problems existing in the prior art, this utility model discloses a disposable bioreactor bag capable of temperature measurement.

[0004] A disposable bioreactor bag capable of temperature measurement includes a bag body and a temperature measuring device. The temperature measuring device includes a mounting fastener that is sealed to the bag body, a fixing plate that is movably connected to the mounting fastener, and a sensor. The fixing plate has a groove that is adapted to the sensor. When the fixing plate is connected to the mounting fastener, the side of the fixing plate with the groove faces the bag body.

[0005] Specifically, the sensor is fixed to a fixing plate, which is detachably connected to a mounting fastener. The mounting fastener is fixed to the bag body. This structure enables a detachable connection between the sensor and the bag body. At the same time, the relative position between the bag body and the sensor is relatively stable under this structure. Therefore, when this disposable bioreactor bag is applied to a swing bioreactor, there will be no serious displacement between the bag body and the sensor. The sensor can always detect the temperature inside the bag. In addition, since the mounting fastener is an additional component, it can be fixed to the bag body by welding or other methods, without causing inconvenience or difficulty in the production of the bag body.

[0006] Preferably, the mounting fastener is a sliding groove, and the fixing plate is slidably attached to and detached from the sliding groove.

[0007] Specifically, with this structure, the installation and removal of the fixing plate and the slide are very convenient, and it is also very easy to detect whether the installation of the two is in place. This structure has good practicality.

[0008] Preferably, the chute includes a solder pad that is sealed to the bag body and a chute wall provided on the solder pad. A first contact hole is provided on the solder pad at a position that is adapted to the sensor. A soft membrane is provided in the first contact hole, and the sensor is attached to the soft membrane.

[0009] Specifically, in this structure, the liquid inside the bag and the sensor are located on both sides of the soft membrane of the first contact hole. The sensor is in contact with the soft membrane, that is, the sensor and the liquid inside the bag are only separated by the soft membrane. Therefore, the sensor can accurately measure the temperature of the liquid inside the bag.

[0010] Preferably, the bag body is provided with a first clearance hole at the position where it is adapted to the solder pad, and the edge of the solder pad is welded to the first clearance hole.

[0011] Specifically, in this structure, a soft membrane separates the sensor from the liquid inside the bag, making the temperature measurement of the liquid inside the bag more accurate.

[0012] Preferably, the chute includes two parallel and separate chute walls, and each chute wall has a stop strip at the end away from the bag body. The stop strip protrudes in the direction of the other chute wall and is integrally formed with the chute wall.

[0013] Specifically, the structure of the stop strip makes the fixing plate more stable in connection with the mounting fastener, that is, the relative position between the sensor and the soft membrane is more stable, avoiding the failure of detachment, and thus ensuring the accuracy, continuity and stability of the sensor temperature measurement.

[0014] Preferably, the mounting fastener is a buckle groove, which is sealed to the bag body, and the fixing plate is fastened to the buckle groove.

[0015] Specifically, the snap-fit ​​installation structure is easy to assemble and disassemble, and is very easy to replace, making it highly practical.

[0016] Preferably, a second contact hole is provided on the groove at a position that matches the sensor, and a soft membrane is provided in the second contact hole, with the sensor attached to the soft membrane.

[0017] Specifically, this structure can effectively reduce the space between the sensor and the liquid inside the bag, making the sensor's temperature measurement more accurate.

[0018] Preferably, the height of the sensor is greater than the depth of the groove.

[0019] Specifically, in this structure, the sensor protrudes from the groove. After the fixing plate and the mounting fastener are installed, the sensor protruding from the groove comes into contact with the soft membrane of the first clearance hole / second clearance hole. This causes the soft membrane to be stretched to a certain extent, that is, the sensor will be in close contact with the soft membrane. There are no bends or wrinkles on the soft membrane, which further enables the sensor to measure the temperature of the liquid in the bag more accurately.

[0020] Preferably, the mounting fastener is located at a non-seam location on the bag body.

[0021] Specifically, if the mounting fasteners are placed at the seams of the bag, it will cause a significant change in the shape of the entire bag, reducing the applicability of the disposable bioreactor bag and making it impractical.

[0022] Preferably, the fixing plate is further provided with a receiving groove for accommodating the sensor connection wire, and the receiving groove is in communication with the groove.

[0023] Specifically, this structure can effectively prevent the sensor connection wire from being squeezed, thus effectively extending the service life of the sensor connection wire.

[0024] Compared with the prior art, the advantages of this utility model are:

[0025] By utilizing the detachable connection structure of mounting fasteners and fixing plates, a detachable connection between the sensor and the bag body is achieved. After the connection is completed, the sensor is in close contact with the bag body, and the relative position between the two is stable, meaning that the sensor can measure the temperature of the liquid inside the bag in real time and accurately. Attached Figure Description

[0026] Figure 1 This is a schematic diagram of the structure of the disposable bioreactor bag capable of temperature measurement disclosed in this utility model.

[0027] Figure 2 This is a cross-sectional schematic diagram of the temperature-measuring disposable bioreactor bag disclosed in this utility model;

[0028] Figure 3 This is a schematic diagram of the fixing plate of the temperature-measuring disposable bioreactor bag disclosed in this utility model. Detailed Implementation

[0029] The present invention will be further described below with reference to the accompanying drawings and specific embodiments.

[0030] like Figure 1-3 As shown, the disposable bioreactor bag capable of temperature measurement includes a bag body 10 and a temperature measuring device. The temperature measuring device includes a mounting fastener that is sealed to the bag body 10, a fixing plate 20 that is movably connected to the mounting fastener, and a sensor 30. The fixing plate 20 is provided with a groove 21, which is adapted to the sensor 30. When the fixing plate 20 is connected to the mounting fastener, the side of the fixing plate 20 with the groove 21 faces the bag body 10.

[0031] The sensor 30 is fixed on the fixing plate 20, and the fixing plate 20 is detachably connected to the mounting fastener, which is fixed to the bag body 10. This structure enables a detachable connection between the sensor 30 and the bag body 10. At the same time, the relative position between the bag body 10 and the sensor 30 is relatively stable under this structure. Therefore, when this disposable bioreactor bag is applied to a swing bioreactor, there will be no serious displacement between the bag body 10 and the sensor 30. The sensor 30 can always detect the temperature inside the bag body 10. In addition, since the mounting fastener is an additional component, it can be fixed to the bag body 10 by welding or other methods, which will not cause inconvenience or difficulty in the production of the bag body 10.

[0032] The mounting fastener is a sliding groove, and the fixing plate 20 can be slidably installed and removed from the sliding groove.

[0033] With this structure, the installation and removal of the fixing plate 20 and the slide is very convenient, and it is also very easy to detect whether the installation is in place. This structure has good practicality.

[0034] The chute includes a solder pad 41 that is sealed to the bag body 10, and a chute wall 42 provided on the solder pad 41. A first contact hole is provided on the solder pad 41 at a position that is adapted to the sensor 30. A soft membrane is provided in the first contact hole, and the sensor 30 is attached to the soft membrane.

[0035] In this structure, the liquid inside the bag and the sensor 30 are located on both sides of the soft membrane of the first contact hole. The sensor 30 is in contact with the soft membrane, that is, the sensor 30 and the liquid inside the bag are only separated by the soft membrane. Therefore, the sensor 30 can accurately measure the temperature of the liquid inside the bag.

[0036] The bag body 10 is provided with a first clearance hole at the position where it is adapted to the pad 41, and the edge of the pad 41 is welded to the first clearance hole.

[0037] With this structure, a soft membrane separates the sensor 30 from the liquid inside the bag, making the temperature measurement of the liquid inside the bag more accurate.

[0038] The chute includes two parallel and separate chute walls 42. Each chute wall 42 has a stop strip 43 at the end away from the bag body 10. The stop strip 43 protrudes in the direction of the other chute wall 42 and is integrally formed with the chute wall 42.

[0039] The structure of the stop strip 43 makes the fixing plate 20 more stable in connection with the mounting fastener, that is, the relative position between the sensor 30 and the soft membrane will be more stable, avoiding the failure of falling off, and thus ensuring the accuracy, continuity and stability of the temperature measurement of the sensor 30.

[0040] The mounting fastener is a buckle groove, which is sealed to the bag body 10, and the fixing plate 20 is fastened to the buckle groove.

[0041] The snap-fit ​​installation structure is easy to assemble and disassemble, and is very easy to replace, making it highly practical.

[0042] A second contact hole is provided on the groove at the position that is adapted to the sensor 30. A soft membrane is provided in the second contact hole, and the sensor 30 is attached to the soft membrane.

[0043] This structure can effectively reduce the space between the sensor 30 and the liquid inside the bag, making the temperature measurement of the sensor 30 more accurate.

[0044] The height of sensor 30 is greater than the depth of groove 21.

[0045] In this structure, the sensor 30 protrudes from the groove 21. After the fixing plate 20 and the mounting fastener are installed, the sensor 30 protruding from the groove 21 comes into contact with the soft membrane of the first clearance hole / second clearance hole. This will cause the soft membrane to be stretched to a certain extent, that is, the sensor 30 will be in close contact with the soft membrane. There are no bends or wrinkles on the soft membrane, which further enables the sensor 30 to measure the temperature of the liquid in the bag more accurately.

[0046] The mounting fasteners are located at the non-seam locations of the bag body 10.

[0047] If the mounting fastener is placed at the seam of the bag body 10, it will cause a significant change in the shape of the entire bag body 10, which will reduce the applicability of the disposable bioreactor bag and make it impractical.

[0048] The fixing plate 20 is also provided with a receiving groove 22 for accommodating the sensor connection wire, and the receiving groove 22 is connected to the groove 21.

[0049] This structure effectively prevents the sensor connection wires from being squeezed, thus extending their service life.

Claims

1. A disposable bioreactor bag capable of temperature measurement, comprising a bag body and a temperature measuring device, characterized in that, The temperature measuring device includes a mounting fastener that is sealed to the bag body, a fixing plate that is movably connected to the mounting fastener, and a sensor. The fixing plate has a groove that is adapted to the sensor. When the fixing plate is connected to the mounting fastener, the side of the fixing plate with the groove faces the bag body.

2. The disposable bioreactor bag capable of temperature measurement according to claim 1, characterized in that, The mounting fastener is a sliding groove, and the fixing plate is slidably attached to and detached from the sliding groove.

3. The disposable bioreactor bag capable of temperature measurement according to claim 2, characterized in that, The chute includes a solder pad that is sealed to the bag body, and a chute wall provided on the solder pad. A first contact hole is provided on the solder pad at a position that is adapted to the sensor. A soft membrane is provided in the first contact hole, and the sensor is attached to the soft membrane.

4. The disposable bioreactor bag capable of temperature measurement according to claim 3, characterized in that, The bag body is provided with a first clearance hole at the position where it is adapted to the pad, and the edge of the pad is welded to the first clearance hole.

5. The disposable bioreactor bag capable of temperature measurement according to claim 3, characterized in that, The chute wall includes two parallel and separate sections. Each chute wall has a stop strip at the end away from the bag body. The stop strip protrudes in the direction of the other chute wall and is integrally formed with the chute wall.

6. The disposable bioreactor bag capable of temperature measurement according to claim 1, characterized in that, The mounting fastener is a buckle groove, which is sealed to the bag body, and the fixing plate is fastened to the buckle groove.

7. The disposable bioreactor bag capable of temperature measurement according to claim 6, characterized in that, The groove is provided with a second contact hole at a position that matches the sensor. The second contact hole is provided with a soft membrane, and the sensor is attached to the soft membrane.

8. The disposable bioreactor bag capable of temperature measurement according to claim 3 or 7, characterized in that, The height of the sensor is greater than the depth of the groove.

9. The disposable bioreactor bag capable of temperature measurement according to claim 1, characterized in that, The mounting fastener is located at the non-seam part of the bag body.

10. The disposable bioreactor bag capable of temperature measurement according to claim 1, characterized in that, The fixing plate is also provided with a receiving groove for accommodating the sensor connection wire, and the receiving groove is connected to the groove.

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