Embryo microinjection needle with anti-blocking structure
Patent Information
- Application Number
- CN202522159324.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-10-13
- Publication Date
- 2026-10-27
- Estimated Expiration
- 2035-10-13
AI Technical Summary
[0003]在胚胎工程研究及辅助生殖技术中,胚胎显微注射是一项关键操作,其主要通过显微注射针将外源基因、核酸、蛋白质或药物等物质精准注入胚胎内部,以实现基因编辑、胚胎改造或疾病模型构建等目的,然而,传统的胚胎显微注射针在实际使用过程中,普遍存在易堵塞的问题:一方面,注射针的针尖开口细小,胚胎内的胞质颗粒、细胞膜碎片或注射液中的微量杂质易附着在针尖内壁或开口处,导致注射通道堵塞,另一方面,传统注射针多为单一的直通道结构,堵塞后难以清理,只能更换新的注射针,不仅增加了实验成本,还可能因频繁更换注射针延长操作时间,影响胚胎的活性与实验效率
该具有防堵塞结构的胚胎显微注射针,通过注射器本体、注射头、弧形板以及防堵组件的配合设置,防堵组件能够实现对注射器本体内部杂质的清理,进而在使用过程中无需更换新的注射器本体,进而不会增加实验成本,进而不会影响到胚胎的活性与实验效率。
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Figure CN224901267U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of embryo engineering technology, specifically to an embryo microinjection needle with an anti-blocking structure. Background Technology
[0002] Embryo microinjection is a biotechnology that uses a microscope to precisely inject exogenous substances (such as DNA, RNA, proteins, cells, or small molecule compounds) into specific parts of an embryo (such as the cytoplasm, nucleus, yolk sac, etc.). It is one of the core technologies in modern molecular biology, developmental biology, and assisted reproductive technology (ART), providing a key tool for research and clinical applications such as gene editing, disease model construction, and embryo engineering.
[0003] In embryo engineering research and assisted reproductive technology, embryo microinjection is a crucial procedure. It involves precisely injecting exogenous genes, nucleic acids, proteins, or drugs into the embryo using a microinjection needle to achieve purposes such as gene editing, embryo modification, or disease model construction. However, traditional embryo microinjection needles commonly suffer from clogging issues in practical use. Firstly, the needle tip opening is small, allowing cytoplasmic particles, cell membrane fragments, or trace impurities in the injection solution to easily adhere to the inner wall of the needle tip or the opening, leading to blockage. Secondly, traditional needles are mostly single-channel structures, making them difficult to clean after clogging, requiring replacement with a new needle. This not only increases experimental costs but can also prolong operation time due to frequent needle changes, affecting embryo viability and experimental efficiency. Therefore, we provide an embryo microinjection needle with an anti-clogging structure. Utility Model Content
[0004] To address the shortcomings of existing technologies, this invention provides an embryo microinjection needle with an anti-blockage structure, thus solving the problems mentioned in the background section.
[0005] To achieve the above objectives, this utility model provides the following technical solution: an embryo microinjection needle with an anti-clogging structure, comprising a syringe body, one end of which is connected to an injection head, two arc-shaped plates symmetrically mounted on the outer surface of the syringe body, and an anti-clogging component for unblocking the syringe body installed inside the syringe body, the anti-clogging component comprising a push rod disposed inside the syringe body, a circular plate fixedly connected to the top end of the push rod, and a circular rubber ring fixedly connected to the bottom end of the push rod, the outer surface of which contacts the inner wall of the syringe body.
[0006] Preferably, the anti-clogging component further includes two guide grooves formed inside the syringe body, and a slide rod is installed inside each of the two guide grooves.
[0007] Preferably, both slide rods have sliders slidably connected to their outer surfaces, and springs are installed between the sliders and the guide grooves.
[0008] Preferably, a connecting rod is mounted on the outer surface of both sliders, and the connecting rod is made of iron.
[0009] Preferably, two magnets are fixedly connected to the outer surface of the circular rubber ring, and the magnets are attracted to the connecting rod.
[0010] Preferably, both of the curved plates are made of acrylic, and the curved plates are located above the injection head.
[0011] This invention provides an embryo microinjection needle with an anti-blocking structure. It has the following beneficial effects: This embryo microinjection needle with an anti-clogging structure, through the coordinated arrangement of the syringe body, injection head, arc plate and anti-clogging component, can clean impurities inside the syringe body, so there is no need to replace the syringe body during use, thus not increasing experimental costs, and not affecting the viability of the embryo and experimental efficiency.
[0012] This embryo microinjection needle with an anti-clogging structure is designed with a push rod, a circular plate, a circular rubber ring, a guide groove, a slide rod, a slider, a spring, a connecting rod, and a magnet. When the syringe body becomes clogged, the circular plate first presses down on the push rod. During this process, the circular rubber ring connected to the push rod adheres tightly to the inner wall of the syringe body and moves downwards synchronously. As the rubber ring moves, the air inside the syringe body is gradually compressed, and the internal pressure increases accordingly. The compressed air creates positive pressure. When the circular rubber ring continues to move downwards, and the internal pressure of the syringe body reaches a certain threshold, the high-pressure airflow exerts a thrust on the blockage, expelling it from the syringe port, thus clearing the blockage inside the syringe body. This operation effectively removes blockages, ensuring the normal operation of subsequent devices and preventing blockages from affecting drug delivery or injection functions. Attached Figure Description
[0013] Figure 1 This is a three-dimensional structural schematic diagram of the front view of this utility model; Figure 2 This is a sectional view of the front view of this utility model; Figure 3 This is a three-dimensional structural diagram of the push rod of this utility model; Figure 4 This utility model Figure 2 A magnified three-dimensional structural diagram at point A in the middle.
[0014] In the diagram: 1. Syringe body; 2. Injection head; 3. Arc plate; 4. Anti-clogging component; 401. Push rod; 402. Circular plate; 403. Circular rubber ring; 404. Guide groove; 405. Slide rod; 406. Slider; 407. Spring; 408. Connecting rod; 409. Magnet. Detailed Implementation
[0015] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0016] like Figure 1-4 As shown, this utility model provides a technical solution: an embryo microinjection needle with an anti-clogging structure, comprising a syringe body 1, one end of which is connected to an injection head 2. The syringe body 1 serves as the core liquid storage component, stably storing liquid and providing sufficient liquid reserves for subsequent injection operations, ensuring the continuity of the injection process. The corresponding injection head 2 plays a crucial role in liquid output, accurately exporting the liquid stored in the syringe body 1. Through the cooperation of the liquid storage function of the syringe body 1 and the liquid output function of the injection head 2, the core injection function of the entire device is ultimately realized, meeting the requirements for liquid delivery.
[0017] Two arc-shaped plates 3 are symmetrically mounted on the outer surface of the syringe body 1. Both arc-shaped plates 3 are made of acrylic and are located above the injection head 2. The use of acrylic material in this device is lightweight, effectively reducing the overall weight of the device. This design advantage significantly reduces the burden on operators during subsequent carrying and actual use, avoiding inconvenience caused by excessive weight, thus ensuring smooth injection operation, ensuring that subsequent injection efficiency is not affected, and further improving the user experience of the device.
[0018] The syringe body 1 is equipped with an anti-clogging component 4 for unblocking the syringe body 1. The anti-clogging component 4 includes a push rod 401, which is located inside the syringe body 1. A circular plate 402 is fixedly connected to the top of the push rod 401. The circular plate 402 can provide certain convenience for the subsequent pushing of the push rod 401, thereby ensuring normal use in the future.
[0019] A circular rubber ring 403 is fixedly connected to the bottom end of the push rod 401, and the outer surface of the circular rubber ring 403 is in contact with the inner wall of the syringe body 1. The circular rubber ring 403 can squeeze out the impurities that cause blockage inside the syringe body 1, thereby ensuring the subsequent use effect of the syringe body 1.
[0020] The anti-clogging component 4 also includes two guide grooves 404 formed inside the syringe body 1. Each guide groove 404 has a slide rod 405 installed inside it. The outer surfaces of the two slide rods 405 are slidably connected to sliders 406. A spring 407 is installed between the sliders 406 and the guide grooves 404. The springs 407 provide a certain reset capability for the movement of the sliders 406, thereby ensuring the effectiveness of the sliders 406. At the same time, the sliding connection between the slide rods 405 and the sliders 406 guides the movement of the sliders 406, ensuring the effective movement of the sliders 406.
[0021] Both sliders 406 have connecting rods 408 mounted on their outer surfaces. The connecting rods 408 are made of iron. Two magnets 409 are fixedly connected to the outer surface of the circular rubber ring 403. The magnets 409 are attracted to the connecting rods 408. Through the connection between the connecting rods 408 and the magnets 409, the circular rubber ring 403 can be adjusted, thereby ensuring the normal operation of subsequent unblocking work.
[0022] In use, when the syringe body 1 becomes clogged, the push rod 401 is first pressed down by the circular plate 402. During this process, the circular rubber ring 403 moves and adheres to the inside of the syringe body 1, gradually compressing the air inside the syringe body 1, thus creating a negative pressure state inside the syringe body 1. As the circular rubber ring 403 continues to move, the pressure inside the syringe body 1 reaches a certain level, which will expel the clogged material, thereby clearing the blockage inside the syringe body 1 and ensuring the effectiveness of subsequent device use. At the same time, all contents not described in detail in this specification are existing technologies known to those skilled in the art.
[0023] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitations, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.
[0024] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.
Claims
1. An embryo microinjection needle with an anti-blocking structure, comprising a syringe body (1), characterized in that: One end of the syringe body (1) is connected to the injection head (2). Two arc-shaped plates (3) are symmetrically installed on the outer surface of the syringe body (1). An anti-blocking component (4) for unblocking the syringe body (1) is installed inside the syringe body (1). The anti-blocking component (4) includes a push rod (401). The push rod (401) is located inside the syringe body (1). A circular plate (402) is fixedly connected to the top end of the push rod (401). A circular rubber ring (403) is fixedly connected to the bottom end of the push rod (401). The outer surface of the circular rubber ring (403) is in contact with the inner wall of the syringe body (1).
2. The embryo microinjection needle with an anti-blockage structure according to claim 1, characterized in that: The anti-blocking component (4) also includes two guide grooves (404) opened inside the syringe body (1), and a slide rod (405) is installed inside each of the two guide grooves (404).
3. The embryo microinjection needle with an anti-blockage structure according to claim 2, characterized in that: Both of the slide rods (405) have sliders (406) slidably connected to their outer surfaces, and a spring (407) is installed between the slider (406) and the guide groove (404).
4. The embryo microinjection needle with an anti-blocking structure according to claim 3, characterized in that: Both sliders (406) have connecting rods (408) mounted on their outer surfaces, and the connecting rods (408) are made of iron.
5. The embryo microinjection needle with an anti-blocking structure according to claim 1, characterized in that: Two magnets (409) are fixedly connected to the outer surface of the circular rubber ring (403), and the magnets (409) are attracted to the connecting rod (408).
6. The embryo microinjection needle with an anti-blockage structure according to claim 1, characterized in that: Both of the arc plates (3) are made of acrylic, and the arc plates (3) are located above the injection head (2).