A well plate sample loading marker device
Patent Information
- Application Number
- CN202522562737.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-12-02
- Publication Date
- 2026-10-27
- Estimated Expiration
- 2035-12-02
AI Technical Summary
[0002]96孔板是实验室常见的微孔板,因一个板上有96个独立小孔而得名,常用于高通量筛选、细胞培养、酶联免疫吸附测定(ELISA)、实时荧光定量PCR等实验;针对目前使用孔板(96格)进行加样操作时,由于目前孔板上孔洞较多,且现有数字/字母标记均为透明色,人工加样时无法清晰识别,在医护人员操作样本的逐一加样时容易弄混,后续需要确认加样具体孔位时还需反复核对,效率较低,目前虽然存在专利提出一些孔板标记工具,但是大多结构较为复杂,拆装不便,不方便后续清洗消毒
[0011](1)本方案通过设置的96孔板配合顶部安放的区分板,在区分板上设置四个加注口分别对应96孔板的两排孔眼,同时区分板上横竖设置多排显眼的数字标识,使得操作人员在孔眼内侧加样式,能够分区域操作,每个区域只有两排孔眼,配合显眼的数字标识,可快速标记加注孔眼,方便复核,提高操作便捷性;
Smart Images

Figure CN224901278U_ABST
Abstract
Description
Technical Field
[0001] This utility model belongs to the field of experimental well plate technology, specifically relating to a well plate sample labeling device. Background Technology
[0002] 96-well plates are common microplates in laboratories, named for their 96 individual wells. They are frequently used in high-throughput screening, cell culture, enzyme-linked immunosorbent assay (ELISA), and real-time quantitative PCR. However, current methods for adding samples to 96-well plates suffer from drawbacks. The numerous wells and the transparent numerical / letter markings make manual labeling difficult, leading to confusion and requiring repeated checks to confirm the correct well placement. While some patents exist for well labeling tools, most are complex, difficult to disassemble and reassemble, and inconvenient for subsequent cleaning and sterilization. Therefore, a convenient, easy-to-label, easy-to-verify, and easy-to-disassemble / sterilize well plate labeling device is urgently needed. Utility Model Content
[0003] To address the aforementioned problems in the existing technology, this utility model provides a perforated plate sample marking device, which features convenient assembly and disassembly, easy marking, and quick verification.
[0004] To achieve the above objectives, this utility model provides the following technical solution: a perforated plate sample marking device, comprising a base plate and a 96-well plate fixed to its top surface, a positioning plate symmetrically fixed to the top edge of the base plate, the positioning plate being located on both sides of the 96-well plate, a distinguishing plate being provided above the 96-well plate, and a U-shaped clamping plate symmetrically fixed to the bottom edge of the distinguishing plate, the U-shaped clamping plate clamping the outside of the positioning plate; the top surface of the distinguishing plate is provided with four sets of filling ports, each set of filling ports covering two rows of holes, a horizontal mark being provided on the top edge of the distinguishing plate, and a vertical mark being provided on the top edge of the distinguishing plate, the filling holes being quickly located by the vertical mark in conjunction with the horizontal mark, facilitating counting.
[0005] As a preferred technical solution of the orifice plate sample marking device of this utility model, a slot is provided on the outer side of the top surface of the injection port, and a transparent baffle is inserted into the inner side of the slot to shield and protect the 96-hole plate.
[0006] As a preferred technical solution of the orifice plate sample marking device of this utility model, the number of transparent baffles is the same as the number of injection ports, and the top edge of the transparent baffles is symmetrically fixed with traction plates for manual disassembly of the transparent baffles.
[0007] As a preferred technical solution of the orifice plate sample marking device of this utility model, an elastic silicone extrusion pad is fixed on one side wall of the U-shaped clamp. The extrusion pad is located between the U-shaped clamp and the 96-well plate and is attached to the outer wall of the 96-well plate.
[0008] As a preferred technical solution of the orifice plate sample marking device of this utility model, the number of vertical markings corresponds to the number of rows of the 96-well plate, and the number of horizontal markings corresponds to the number of columns of the 96-well plate.
[0009] As a preferred technical solution of the orifice plate sample marking device of this utility model, the top surface of the 96-well plate abuts against the bottom surface of the dividing plate.
[0010] Compared with the prior art, the beneficial effects of this utility model are:
[0011] (1) This scheme uses a 96-hole plate and a top-mounted dividing plate to set up four filling ports on the dividing plate, which correspond to the two rows of holes on the 96-hole plate. At the same time, multiple rows of conspicuous numerical markings are set on the dividing plate, so that the operator can add patterns inside the holes and operate in different areas. Each area has only two rows of holes. With the conspicuous numerical markings, the filling holes can be quickly marked, which is convenient for verification and improves the convenience of operation.
[0012] (2) This solution uses a transparent baffle and a slot on the outside of each filling port. The transparent baffle can be inserted into the slot to block the two rows of holes below. When filling the holes in the current area, the holes in other areas can be blocked to prevent the sample from splashing into other holes. At the same time, the transparent material makes it easy for the operator to observe the sample filling situation in other holes, further improving the ease of operation.
[0013] (3) This solution adds a positioning plate to the 96-hole plate tool by setting a U-shaped clamp and positioning plate. It can be integrally formed during production. The distinguishing plate is clamped on the positioning plate by the U-shaped clamp, which realizes the convenient installation of the distinguishing tool. After subsequent disassembly, the distinguishing plate has no dead corners for hygiene. The structure is simple and convenient for thorough cleaning and disinfection. Attached Figure Description
[0014] The accompanying drawings are provided to further illustrate the present invention and form part of the specification. They are used together with the embodiments of the present invention to explain the present invention, but do not constitute a limitation thereof. In the drawings:
[0015] Figure 1 This is a schematic diagram of the overall structure of this utility model;
[0016] Figure 2 This is a schematic diagram showing the connection between the 96-hole plate and the dividing plate of this utility model;
[0017] Figure 3 This is a three-dimensional schematic diagram of the 96-hole plate of this utility model;
[0018] Figure 4 This is a three-dimensional schematic diagram of the differentiating plate of this utility model.
[0019] In the diagram: 1. Base plate; 11. Positioning plate; 2. 96-hole plate; 3. Differentiating plate; 31. Vertical marking; 32. Horizontal marking; 33. Slot; 34. Filling port; 35. U-shaped clamp; 36. Extrusion pad; 4. Transparent baffle; 41. Traction plate. Detailed Implementation
[0020] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0021] Reference Figure 1 , 3 and Figure 4 As shown, specifically, a microplate sample marking device includes a base plate 1 and a 96-well plate 2 fixed on its top surface. The base plate 1 and the 96-well plate 2 form a common microplate structure with 8 rows and 12 columns of a total of 96 holes. The specific operating principle and application scenarios can be referred to the existing technology, so they are not described in detail here. The top edge of the base plate 1 is symmetrically fixed with positioning plates 11, which are located on both sides of the 96-well plate 2. During production, they can be integrally formed with the microplate. A dividing plate 3 is provided above the 96-well plate 2. The top surface of the dividing plate 3 is provided with four sets of filling ports 34, each set of filling ports 34 covering two rows of holes. The four sets of filling ports 34 divide the 96-well plate 2 into four areas, each area containing only two rows of holes. This makes it less likely to mix up the samples and allows operators to quickly determine the sample filling positions, facilitating subsequent calculations and improving operational efficiency.
[0022] Furthermore, the top edge of the distinguishing plate 3 is provided with horizontal markings 32, the number of which corresponds to the number of columns in the 96-well plate 2, that is, there are 12 horizontal markings 32 on both the top and bottom sides (numbers 1-12 respectively). The top edge of the distinguishing plate 3 is provided with vertical markings 31, the number of which corresponds to the number of rows in the 96-well plate 2, that is, there are 8 vertical markings 31 on both the left and right sides (numbers 1-8 respectively). The markings are in bright colors, making them intuitive and eye-catching. By using the vertical markings 31 in conjunction with the horizontal markings 32, the injection holes can be quickly located. When adding samples, the operator can quickly mark the holes that need to be added, and at the same time, it is convenient to check the sample quantity when the sample is added. The counting is quick and convenient, further improving the operational efficiency.
[0023] Furthermore, U-shaped clamps 35, made of elastic material, are symmetrically fixed to the bottom edge of the distinguishing plate 3. The U-shaped clamps 35 are clamped on the outside of the positioning plate 11, and the positioning plate 11 and the U-shaped clamps 35 are interference fit. An elastic silicone extrusion pad 36 is fixed to one side wall of the U-shaped clamp 35. The extrusion pad 36 is located between the U-shaped clamp 35 and the 96-hole plate 2 and fits against the outer wall of the 96-hole plate 2, further improving the installation stability. By setting the U-shaped clamp 35 and the positioning plate 11 to elastically clamp, it is easy to install the distinguishing plate 3 and also easy to disassemble. The structure is simple. After disassembly, the entire tool has no dead corners for hygiene and is easy to thoroughly clean and disinfect.
[0024] Reference Figure 1 and Figure 2 As shown, specifically, a slot 33 is provided on the outer side of the top surface of the filling port 34. The area of the slot 33 is larger than that of the filling port 34. A transparent baffle 4 is inserted into the inner side of the slot 33. The thickness of the transparent baffle 4 is greater than the depth of the slot 33, which is used to shield and protect the 96-hole plate 2. The number of transparent baffles 4 is the same as that of the filling port 34. A traction plate 41 is symmetrically fixed on the top edge of the transparent baffle 4 for manual removal of the transparent baffle 4. The top surface of the 96-hole plate 2 abuts against the bottom surface of the dividing plate 3.
[0025] Specifically, the 96-well plate 2 is divided into four regions by setting a dividing plate 3. When adding samples to one region, the operator can use a transparent baffle 4 to block other regions to prevent the sample from splashing into the wells of other regions. At the same time, the transparent material makes it easy for the operator to observe the sample addition in the wells of other regions.
[0026] The working principle and usage process of this utility model are as follows: When using a 96-well plate for sample filling, the operator clamps the dividing plate 3 to the outside of the positioning plate 11 on the 96-well plate 2 using a U-shaped clamp 35, ensuring that the dividing plate 3 fits snugly against the top surface of the 96-well plate 2. The operator then adjusts the position of the dividing plate 3 along the positioning plate 11 so that the four sets of filling ports 34 on the dividing plate 3 accurately correspond to the holes on the 96-well plate 2, dividing the 96 holes into four equal parts. Each filling port 34 exposes two rows of holes. During sample filling, the operator... After determining the sample application area, a transparent baffle 4 is inserted inside other application ports 34 to shield and protect the holes in other areas. Then, the sample is applied to the current area. During the application process, the vertical markings 31 and horizontal markings 32 on the edge of the dividing plate 3 facilitate the operator to quickly and accurately locate the sample application holes. It also makes it easy to count the number of samples applied after the application is completed. Afterward, the current area is sealed with the transparent baffle 4, and other application ports 34 can be opened for further application. The operation is convenient. After the application is completed, the dividing plate 3 can be removed for cleaning and disinfection.
[0027] Finally, it should be noted that the above description is merely a preferred embodiment of this utility model and is not intended to limit the utility model. Although the utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.
Claims
1. A sample marking device for a perforated plate, comprising a base plate (1) and a 96-well plate (2) fixed on its top surface, characterized in that: The top edge of the substrate (1) is symmetrically fixed with positioning plates (11), which are located on both sides of the 96-hole plate (2). A dividing plate (3) is provided above the 96-hole plate (2), and a U-shaped clamping plate (35) is symmetrically fixed on the bottom edge of the dividing plate (3). The U-shaped clamping plate (35) is clamped on the outside of the positioning plate (11). The top surface of the dividing plate (3) is provided with four sets of filling ports (34), each set of filling ports (34) covers two rows of holes. The top edge of the dividing plate (3) is provided with a horizontal mark (32), and the top edge of the dividing plate (3) is provided with a vertical mark (31). The filling holes can be quickly located by the vertical mark (31) in conjunction with the horizontal mark (32), which is convenient for counting.
2. The orifice plate sample marking device according to claim 1, characterized in that: The top outer side of the filling port (34) is provided with a slot (33), and a transparent baffle (4) is inserted into the inner side of the slot (33) to shield and protect the 96-hole plate (2).
3. The orifice plate sample marking device according to claim 2, characterized in that: The number of transparent baffles (4) is the same as that of the filling port (34). The top edge of the transparent baffle (4) is symmetrically fixed with a traction plate (41) for manual disassembly of the transparent baffle (4).
4. The orifice plate sample marking device according to claim 3, characterized in that: An elastic silicone extrusion pad (36) is fixed to one side wall of the U-shaped clamp (35). The extrusion pad (36) is located between the U-shaped clamp (35) and the 96-hole plate (2) and is attached to the outer wall of the 96-hole plate (2).
5. The orifice plate sample marking device according to claim 4, characterized in that: The number of vertical markers (31) corresponds to the number of rows of the 96-hole plate (2), and the number of horizontal markers (32) corresponds to the number of columns of the 96-hole plate (2).
6. The orifice plate sample marking device according to claim 5, characterized in that: The top surface of the 96-hole plate (2) abuts against the bottom surface of the dividing plate (3).