A multi-purpose cell culture flask

Abstract

The utility model relates to cell culture technical field, concretely is a multipurpose cell culture bottle, including culture bottle body, one side of culture bottle body is provided with scale line, the culture bottle body side away from scale line is fixedly installed with screw neck, one side of screw neck is provided with sealing rubber ring, the outside of screw neck is provided with cover body mechanism through screw thread, the utility model discloses the collaborative action of adjusting screw drive sealing gasket and air groove, can realize the stepped regulation of air flow passage section area, satisfies the dynamic control demand of different culture stage to gas exchange amount, significantly promotes the flexibility and environmental adaptability of operation, adopts the staggered covering structure of double -layer sealing gasket simultaneously, combines the axial pressure of screw thread drive generation, can be under the non - complete screwing state through mechanical structure compensation micro - gap, maintains the sealing reliability, reduces the operation redundancy.

Description

Technical Field

[0001] This utility model relates to the field of cell culture technology, specifically a multi-purpose cell culture flask. Background Technology

[0002] Cell culture flasks are the cornerstone of in vitro life science research, solving the fundamental challenge that cells cannot survive independently after being removed from the in vivo environment. They provide fragile cells with a sterile, nutritionally balanced, and parameter-controlled living space, enabling scientists to reproduce disease mechanisms, screen life-saving drugs, or analyze gene functions in vitro, thereby accelerating the translation from laboratory discoveries to clinical treatments. Without this medium, breakthroughs in modern medicine would be like water without a source, lacking the most basic experimental support.

[0003] However, existing cell culture flasks typically have fixed gas exchange channels, which cannot dynamically adjust the gas exchange volume according to experimental needs. This limits their application scenarios and operational flexibility. Furthermore, they rely on a fully tightened state or a single sealed interface to achieve a seal, which requires high assembly precision and has poor fault tolerance. If not fully tightened, mechanical gaps can easily cause leakage problems. Utility Model Content

[0004] The purpose of this invention is to provide a multi-purpose cell culture flask to solve the problems mentioned in the background art.

[0005] To achieve the above objectives, this utility model provides the following technical solution: A multi-purpose cell culture flask includes a culture flask body, a graduation line on one side of the culture flask body, a threaded bottle mouth fixedly installed on the side of the culture flask body away from the graduation line, a sealing ring on one side of the threaded bottle mouth, and a cap mechanism provided on the outside of the threaded bottle mouth through threads. The cap mechanism includes a threaded cap, which is installed on the outside of the threaded bottle opening by threads, and a through groove is provided on one side of the threaded cap.

[0006] Preferably, the cover mechanism further includes a first sealing gasket, which is movably disposed in the through groove and fixedly installed on one side of the clamping plate.

[0007] Preferably, the clamping plate is located inside the threaded cover, and a first vent groove is provided on one side of the first sealing gasket and the clamping plate, and a slot is provided on the side of the clamping plate opposite to the first vent groove.

[0008] Preferably, the first sealing gasket and the clamping plate have a through groove on the side near the vent groove, and an adjusting screw passes through the through groove. One side of the adjusting screw is installed in the adjusting groove by a thread.

[0009] Preferably, the adjustment groove is located in the middle of the cover plate, the cover plate is located outside the threaded cover, and a second vent groove is provided on the side of the cover plate near the adjustment groove.

[0010] Preferably, a locking pin is engaged in the slot, and the contact surface between the locking pin and the second sealing gasket is provided with an elastic sealing layer. The locking pin is fixedly installed on one side of the adjusting plate through the second sealing gasket on the side opposite to the slot.

[0011] Preferably, the adjusting plate and the second sealing gasket are coaxially arranged, forming an adjusting hole between them. The adjusting screw is installed in the adjusting hole through a bearing. A third venting groove and a semi-venting groove are symmetrically distributed radially between the adjusting plate and the second sealing gasket.

[0012] Compared with the prior art, the beneficial effects of this utility model are: This multi-purpose cell culture flask, by adjusting the screw to drive the coordinated action of the sealing gasket and the venting groove, can achieve step-wise adjustment of the cross-sectional area of ​​the airflow channel, meet the dynamic control requirements of gas exchange volume at different culture stages, and significantly improve the flexibility of operation and environmental adaptability.

[0013] This multi-purpose cell culture flask employs a staggered covering structure with double-layer sealing gaskets. Combined with the axial pressure generated by the threaded drive, it can compensate for microscopic gaps through mechanical structure in a partially tightened state, maintaining sealing reliability and reducing operational redundancy. Attached Figure Description

[0014] Figure 1 This is a schematic diagram of the overall structure of this utility model; Figure 2 This is a schematic diagram of the structure of the culture bottle body of this utility model; Figure 3 This is a schematic diagram of the cover mechanism of this utility model; Figure 4 This is a schematic diagram of the structure of the clamping plate of this utility model.

[0015] In the diagram: 101, culture flask body; 102, graduation line; 103, threaded bottle neck; 104, sealing ring; 105, cap mechanism; 106, threaded cap; 201, through groove; 202, first sealing gasket; 203, clamping plate; 204, first venting groove; 205, locking groove; 206, through groove; 301, adjusting screw; 302, adjusting groove; 303, cover plate; 304, second venting groove; 305, locking pin; 306, adjusting plate; 401, second sealing gasket; 402, adjusting hole; 403, third venting groove; 404, semi-venting groove. Detailed Implementation

[0016] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0017] Please see Figures 1-4 As shown, this utility model provides a technical solution: A multi-purpose cell culture flask includes a culture flask body 101, a scale line 102 is provided on one side of the culture flask body 101, a threaded bottle mouth 103 is fixedly installed on the side of the culture flask body 101 away from the scale line 102, a sealing ring 104 is provided on one side of the threaded bottle mouth 103, and a cap mechanism 105 is provided on the outside of the threaded bottle mouth 103 by threads. In this embodiment, preferably, the cover mechanism 105 includes a threaded cover 106, which is threadedly installed on the outside of the threaded bottle mouth 103, and a through groove 201 is provided on one side of the threaded cover 106.

[0018] The above scheme enables real-time monitoring of the culture medium volume through the combination of the culture flask body and the graduation lines; the threaded connection between the threaded bottle mouth and the cap mechanism allows for rapid opening and closing of the bottle mouth and initial sealing; and the sealing ring placed at the edge of the threaded bottle mouth ensures an initial seal, preventing liquid leakage or contamination. In this embodiment, preferably, the cover mechanism 105 further includes a first sealing gasket 202, which is movably disposed in the through groove 201 and is fixedly installed on one side of the clamping plate 203.

[0019] The above scheme allows for the opening of a through groove in the threaded cover to enable the passage of the external operating channel; the movable placement of the first sealing gasket within the through groove enables dynamic sealing adjustment; and the clamping plate fixing the first sealing gasket enables stable positioning and synchronous displacement of the sealing assembly.

[0020] In this embodiment, preferably, the clamping plate 203 is located inside the threaded cover 106, and a first venting groove 204 is provided on one side of the first sealing gasket 202 and the clamping plate 203, and a slot 205 is provided on the side of the clamping plate 203 opposite to the first venting groove 204.

[0021] The above scheme enables the opening and closing control of the airflow channel by opening the first ventilation groove on the inner side of the clamping plate; the slot on the side of the clamping plate provides the installation base for the rotation limit structure, and the locking pin achieves a circumferential locking effect.

[0022] In this embodiment, preferably, the first sealing gasket 202 and the clamping plate 203 have a through groove 206 on the side near the vent groove, and an adjusting screw 301 passes through the through groove 206. One side of the adjusting screw 301 is threaded into the adjusting groove 302.

[0023] The above scheme achieves linear guidance of the transmission component by passing the adjusting screw through the slot; linear adjustment of the sealing pressure can be achieved by the threaded engagement of the adjusting screw and the adjusting slot; and the adjustment slot on the outside of the cover plate can achieve protection and force transmission of the operating components.

[0024] In this embodiment, preferably, the adjustment groove 302 is formed in the middle of the cover plate 303, the cover plate 303 is located outside the threaded cover 106, and the cover plate 303 has a second ventilation groove 304 on the side near the adjustment groove 302.

[0025] The above scheme allows for the superposition and control of multi-stage airflow channels by creating a second vent slot in the cover plate; the axial limiting and rotational driving effects of the operating components can be achieved by adjusting the combination structure of the screw and the cover plate. In this embodiment, preferably, a locking pin 305 is engaged and installed in the slot 205, and the contact surface between the locking pin 305 and the second sealing gasket 401 is provided with an elastic sealing layer. The locking pin 305 is fixedly installed on one side of the adjusting plate 306 through the second sealing gasket 401 on the side opposite to the slot 205.

[0026] The above scheme achieves deformation compensation for assembly gaps by setting an elastic sealing layer with a locking pin; it also achieves overall linkage effect of sealing components by fixing the locking pin with an adjusting plate; and it achieves synergistic effect of dual sealing interfaces by cooperating with the second sealing gasket and the locking pin.

[0027] In this embodiment, preferably, the adjusting plate 306 and the second sealing gasket 401 are coaxially arranged, forming an adjusting hole 402 between them. The adjusting screw 301 is installed in the adjusting hole 402 through a bearing. A third venting groove 403 and a semi-venting groove 404 are symmetrically distributed radially between the adjusting plate 306 and the second sealing gasket 401 along the adjusting hole 402.

[0028] The above scheme enables the smooth rotation of the adjusting screw by installing a bearing inside the adjusting hole; the symmetrical distribution of the third vent groove and the semi-vent groove enables a stepped adjustment effect of the airflow cross-sectional area; and the misaligned coverage and elastic compensation of the sealing gasket enables the adaptive maintenance of dynamic sealing reliability.

[0029] In this embodiment, a multi-purpose cell culture flask is used by the user to connect the threaded rod to the threaded bottle neck 103 on the side opposite to the through groove 201. During connection, the sealing ring 104 is clamped between the adjusting plate 306 and the threaded bottle neck 103, sealing the threaded bottle neck 103. When the adjusting screw 301 is turned clockwise, the external thread of the screw engages with the internal thread of the adjusting groove 302, generating a pulling force that pushes the adjusting plate 306 axially towards the cover plate 303. After movement, the clamping plate 203 carries the first sealing gasket 202 forward synchronously, sealing the first sealing gasket 202 with the through groove 201. Simultaneously, the second sealing gasket 401 expands radially under axial pressure, completely sealing the assembly gap between the clamping plate 203 and the adjusting plate 306. The vent grooves are closed in a staggered manner to achieve a fully sealed state. When the adjusting screw 301 is loosened counterclockwise, the locking pin 305 disengages from the locking groove 205, releasing the rotation constraint. At this time, the rotating adjusting plate 306 can drive the second sealing gasket 401 to shift circumferentially relative to the first sealing gasket 202. When the third vent groove 403 completely overlaps with the first and second vent grooves 304, a gas channel with the largest cross-section is formed. When the half-vent groove 404 partially covers the main vent groove, the airflow cross-sectional area is reduced by 50%. When all grooves are completely misaligned, the misalignment of the double-layer sealing gaskets and the deformation compensation of the elastic sealing layer work together to maintain a reliable seal even if it is not fully tightened. During this process, the elastic sealing layer continuously compensates for the micro gaps caused by component tolerances, ensuring the sealing reliability under different working conditions.

[0030] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely preferred examples and are not intended to limit the utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. A multi-purpose cell culture flask, characterized in that: The culture bottle includes a culture bottle body (101), a scale line (102) is provided on one side of the culture bottle body (101), a threaded bottle mouth (103) is fixedly installed on the side of the culture bottle body (101) away from the scale line (102), a sealing ring (104) is provided on one side of the threaded bottle mouth (103), and a cap mechanism (105) is provided on the outside of the threaded bottle mouth (103) through threads; The cap mechanism (105) includes a threaded cap (106), which is threadedly installed on the outside of the threaded bottle mouth (103) and has a through groove (201) on one side.

2. The multi-purpose cell culture flask according to claim 1, characterized in that: The cover mechanism (105) further includes a first sealing gasket (202), which is movably disposed in the through groove (201) and is fixedly installed on one side of the clamping plate (203).

3. A multi-purpose cell culture flask according to claim 2, characterized in that: The clamping plate (203) is located inside the threaded cover (106). A first vent groove (204) is provided on one side of the first sealing gasket (202) and the clamping plate (203). A slot (205) is provided on the side of the clamping plate (203) opposite to the first vent groove (204).

4. A multi-purpose cell culture flask according to claim 3, characterized in that: The first sealing gasket (202) and the clamping plate (203) have a through groove (206) on the side near the vent groove. An adjusting screw (301) passes through the through groove (206), and one side of the adjusting screw (301) is installed in the adjusting groove (302) by a thread.

5. A multi-purpose cell culture flask according to claim 4, characterized in that: The adjustment groove (302) is located in the middle of the cover plate (303), the cover plate (303) is located outside the threaded cover (106), and a second vent groove (304) is provided on the side of the cover plate (303) near the adjustment groove (302).

6. A multi-purpose cell culture flask according to claim 5, characterized in that: A locking pin (305) is fitted into the slot (205). The contact surface between the locking pin (305) and the second sealing gasket is provided with an elastic sealing layer. The locking pin (305) is fixedly installed on one side of the adjusting plate (306) through the second sealing gasket (401) on the side opposite to the slot (205).

7. A multi-purpose cell culture flask according to claim 6, characterized in that: The adjusting plate (306) and the second sealing gasket (401) are coaxially arranged, forming an adjusting hole (402) between them. The adjusting screw (301) is installed in the adjusting hole (402) through a bearing. A third vent groove (403) and a semi-vent groove (404) are symmetrically distributed radially between the adjusting plate (306) and the second sealing gasket (401) along the adjusting hole (402).

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