A rapid elution antigen detection sampling tube structure
Patent Information
- Application Number
- CN202522145386.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-10-11
- Publication Date
- 2026-10-27
- Estimated Expiration
- 2035-10-11
AI Technical Summary
传统采样管多为单一塑料材质制成,整体结构简单,在实际操作中,咽拭子采集样本后插入传统采样管的洗脱液中,需操作人员反复手动挤压拭子(通常需挤压5-10次)、并将拭子在液体中浸泡10-20秒以上,才能勉强实现抗原的初步释放
1、本装置设置了摩擦机构,仅需轻旋或轻压拭子即可实现抗原快速脱落,无需反复挤压,既避免拭子纤维断裂污染样本,又减少手动操作步骤,降低操作人员劳动强度,同时避免因挤压力度不均导致的洗脱不充分问题;
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Figure CN224901296U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of antigen detection sampling tube technology, and in particular to a structure of an antigen detection sampling tube that can be rapidly eluted. Background Technology
[0002] Antigen testing sampling tubes are the core sample processing component in the antigen detection process for pathogens such as COVID-19. Their main function is to contain the eluent. Traditional sampling tubes are mostly made of a single plastic material with a simple overall structure. In actual operation, after the throat swab sample is collected, it is inserted into the eluent of the traditional sampling tube. The operator needs to manually squeeze the swab repeatedly (usually 5-10 times) and soak the swab in the liquid for more than 10-20 seconds to barely achieve the initial release of antigen.
[0003] This process has several drawbacks: First, repeated squeezing can easily cause the swab fibers to break, and the broken fibers mixed into the elution solution may interfere with the subsequent antigen-antibody reaction, increasing the risk of false positives or false negatives; Second, prolonged soaking significantly extends the sample processing time, which can easily cause congestion in the testing process and reduce overall testing efficiency in large-scale centralized testing scenarios (such as community screening and enterprise testing); Third, it is difficult to uniformly apply manual squeezing force. When some operators do not squeeze sufficiently, the antigen cannot be completely detached from the swab fibers, resulting in insufficient antigen concentration in the elution solution, further increasing the probability of false negatives. In order to solve the above problems, this utility model proposes a rapid elution antigen detection sampling tube structure. Utility Model Content
[0004] The main objective of this invention is to provide a rapidly elutable antigen detection sampling tube structure, which can effectively solve the problems in the background art.
[0005] To achieve the above objectives, the present invention adopts the following technical solution: A rapid-eluting antigen detection sampling tube structure includes a sampling tube body and a tube cap. The side wall of the sampling tube body is connected to the tube cap via a connecting strap. The sampling tube body is provided with a friction mechanism for rubbing a pharyngeal swab. The friction mechanism includes a plurality of first protrusions fixedly connected to the side wall of the sampling tube body. The plurality of first protrusions at the same height are equally spaced. The sampling tube body is provided with a squeezing mechanism for squeezing the pharyngeal swab.
[0006] Preferably, the squeezing mechanism includes a plurality of squeezing blades fixedly connected to the inner wall of the sampling tube body, and the plurality of squeezing blades are arranged at equal intervals.
[0007] Preferably, the inner wall of the sampling tube body is fixedly connected with a plurality of second protrusions, and the plurality of second protrusions are arranged at equal intervals.
[0008] Preferably, the lower end of the tube cap is connected to an extrusion tube, and a sealing cap is threadedly connected to the side wall of the extrusion tube.
[0009] Preferably, a connecting rope is fixedly connected to the side wall of the sampling tube body, a warning ball is provided at the lower end of the connecting rope, and a colored strip is provided on the side wall of the sampling tube body.
[0010] Preferably, the warning ball is made of iron, and the liquid-squeezing sheet is arranged at an angle.
[0011] Compared with the prior art, the present invention has the following beneficial effects: 1. This device is equipped with a friction mechanism, which can quickly remove antigens by simply rotating or pressing the swab, without the need for repeated squeezing. This avoids swab fiber breakage and sample contamination, reduces manual operation steps, lowers the labor intensity of operators, and avoids the problem of insufficient elution caused by uneven squeezing force. 2. This device is equipped with a squeezing mechanism. The squeezing action of the squeezing plate on the pulled-out swab can squeeze the eluent adsorbed by the swab back into the main body of the sampling tube, avoiding insufficient sample volume due to liquid carry-out and ensuring that the antigen concentration in the eluent meets the standard. 3. This device is equipped with a connecting rope, a warning ball, and a colored strip. The combination of the connecting rope, the warning ball, and the colored strip can guide the main body of the sampling tube to remain vertical, ensuring that the swab is completely submerged, further avoiding the risk of false negatives due to insufficient immersion and improving the accuracy of test results; 4. This device is equipped with an extrusion tube and a sealing cap. Connecting the extrusion tube and the sealing cap facilitates subsequent liquid collection and prevents leakage, thereby reducing the probability of sample contamination and improving overall practicality. Attached Figure Description
[0012] Figure 1 This is a schematic diagram of the structure of a rapid-eluting antigen detection sampling tube proposed in this utility model; Figure 2 This is a side view of the structure of a rapid-eluting antigen detection sampling tube proposed in this utility model; Figure 3 This is another side view of the structure of a rapid-eluting antigen detection sampling tube proposed in this utility model.
[0013] In the diagram: 1. Sampling tube body, 2. First protrusion, 3. Second protrusion, 4. Squeezing plate, 5. Connecting strap, 6. Tube cap, 7. Extrusion tube, 8. Sealing cap, 9. Connecting rope, 10. Warning ball, 11. Colored strip. Detailed Implementation
[0014] To make the technical means, creative features, objectives and effects of this utility model easier to understand, the present utility model will be further described below in conjunction with specific embodiments.
[0015] like Figure 1-3 As shown, a rapid-eluting antigen detection sampling tube structure includes a sampling tube body 1 and a tube cap 6. The side wall of the sampling tube body 1 is connected to the tube cap 6 via a connecting strap 5. The sampling tube body 1 is provided with a friction mechanism for rubbing a pharyngeal swab. The friction mechanism includes multiple first protrusions 2 fixedly connected to the side wall of the sampling tube body 1. The multiple first protrusions 2 at the same height are equally spaced. There are two groups of first protrusions 2, with five in each group.
[0016] The sampling tube body 1 is equipped with a squeezing mechanism for squeezing the throat swab. The squeezing mechanism includes multiple squeezing pads 4 fixedly connected to the inner wall of the sampling tube body 1. The multiple squeezing pads 4 are arranged at equal intervals.
[0017] In this invention, a plurality of second protrusions 3 are fixedly connected to the inner wall of the sampling tube body 1. The plurality of second protrusions 3 are arranged at equal intervals. There are five second protrusions 3 in each group. The first protrusion 2 and the second protrusion 3 are misaligned, which can form a "three-dimensional cross" friction structure in the sampling tube body 1. Compared with protrusions in a single direction, the misalignment can greatly increase the frequency and contact area of the swab fibers with the protrusions. Even if the swab moves only slightly, it can generate friction with the first protrusion 2 and the second protrusion 3 respectively, further destroying the adhesion of the antigen on the swab surface, significantly improving the antigen shedding efficiency, and providing a dual structural guarantee for "rapid elution".
[0018] In this invention, the lower end of the tube cap 6 is connected to an extrusion tube 7, and a sealing cap 8 is threadedly connected to the side wall of the extrusion tube 7. The extrusion tube 7 can be directly used as a subsequent "liquid extraction channel". After the antigen is eluted, there is no need to open the tube cap 6 (to avoid sample contamination). Only the sealing cap 8 needs to be unscrewed to extract or squeeze the eluent into the test card through the extrusion tube 7, simplifying the detection operation steps. The threaded connection of the sealing cap 8 has strong sealing performance, which can effectively prevent the eluent from leaking from the extrusion tube 7 during storage or transportation, and at the same time prevent external dust and microorganisms from entering the sampling tube body 1 to contaminate the sample, ensuring sample stability.
[0019] In this invention, a connecting rope 9 is fixedly connected to the side wall of the sampling tube body 1. A warning ball 10 is provided at the lower end of the connecting rope 9. A colored strip 11 is provided on the side wall of the sampling tube body 1. The warning ball 10 is made of iron (mentioned later). Its weight is sufficient to ensure that the connecting rope 9 is always vertical. The colored strip 11 serves as a visual reference and can guide the operator to quickly adjust the sampling tube body 1 to a vertical position. At this time, the pharyngeal swab can be completely immersed in the elution solution after insertion, avoiding the swab from not contacting the liquid due to the tilt of the sampling tube body 1. This ensures that the antigen and the elution solution can fully interact, indirectly improving the elution adequacy. At the same time, the connecting rope 9 can prevent the warning ball 10 from being lost, ensuring that the "vertical positioning function" is usable for a long time.
[0020] In this invention, the warning ball 10 is made of iron, which allows the connecting rope 9 to remain vertical. The squeezing plate 4 is set at an angle, which allows the squeezed liquid to flow back into the sampling tube body 1.
[0021] When in use, the operator inserts the pharyngeal swab after sample collection into the main body 1 of the sampling tube containing the elution solution. Unlike traditional sampling tubes, there is no need to repeatedly squeeze the swab manually. Simply rotate the swab gently or press it slightly towards the tube wall. The swab fibers can then fully contact the first protrusion 2 and generate rapid friction. The protruding structure of the first protrusion 2 can directly destroy the adhesion of viral antigens on the surface of the swab fibers (such as van der Waals forces, hydrogen bonds, etc.), causing the antigens originally attached to the fibers to quickly detach and dissolve into the elution solution in the main body 1 of the sampling tube. This significantly shortens the transfer time of antigens from the "swab" to the "liquid" and achieves preliminary rapid elution. When the swab moves within the sampling tube body 1, its fibers first rub against the first protrusion 2, and then immediately come into contact with the staggered second protrusion 3 and generate secondary friction. Compared to protrusions in a single direction, this "cross-shaped" friction allows the swab fibers to be subjected to more mechanical forces per unit time, making it easier for the antigen to completely detach from the fibers during repeated friction. At the same time, the staggered arrangement can also cover the "friction blind spots" of the swab fibers (such as the fiber sides that a single protrusion cannot reach), ensuring that the antigens in each area of the swab can be quickly detached, further enhancing the "rapid elution" effect. After the throat swab is soaked in the elution solution, its fibers swell due to water absorption. When the operator pulls the swab out of the sampling tube body 1, the swollen swab fibers will come into close contact with multiple squeezing pads 4. The squeezing pads 4 will apply uniform squeezing force to the swab, squeezing out the elution solution attached to the gaps between the fibers. Because the squeezing pads 4 are tilted, the squeezed liquid can flow back into the sampling tube body 1 along the surface of the squeezing pads 4, avoiding liquid loss caused by the elution solution being carried out of the tube with the swab. This process not only reduces sample waste, but also ensures that the sampling tube body 1 always maintains a sufficient concentration of antigen solution, without the need for additional elution solution or extended soaking time, indirectly ensuring the effectiveness of "rapid elution".
[0022] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claims. The scope of protection of this utility model is defined by the appended claims and their equivalents.
Claims
1. A rapidly elutable antigen detection sampling tube structure, comprising a sampling tube body (1) and a tube cap (6), characterized in that, The side wall of the sampling tube body (1) is connected to the tube cap (6) by a connecting strap (5). The sampling tube body (1) is provided with a friction mechanism for rubbing the pharyngeal swab. The friction mechanism includes a plurality of first protrusions (2) fixedly connected to the side wall of the sampling tube body (1). The plurality of first protrusions (2) at the same height are equally spaced. The sampling tube body (1) is provided with a squeezing mechanism for squeezing the pharyngeal swab.
2. The rapidly elutable antigen detection sampling tube structure according to claim 1, characterized in that, The squeezing mechanism includes multiple squeezing blades (4) fixedly connected to the inner wall of the sampling tube body (1), and the multiple squeezing blades (4) are arranged at equal intervals.
3. The rapidly elutable antigen detection sampling tube structure according to claim 2, characterized in that, The inner wall of the sampling tube body (1) is fixedly connected with a plurality of second protrusions (3), and the plurality of second protrusions (3) are arranged at equal intervals.
4. The rapidly elutable antigen detection sampling tube structure according to claim 3, characterized in that, The lower end of the tube cap (6) is connected to an extrusion tube (7), and a sealing cap (8) is threadedly connected to the side wall of the extrusion tube (7).
5. The rapidly elutable antigen detection sampling tube structure according to claim 4, characterized in that, A connecting rope (9) is fixedly connected to the side wall of the sampling tube body (1), and a warning ball (10) is provided at the lower end of the connecting rope (9). A colored strip (11) is provided on the side wall of the sampling tube body (1).
6. The rapidly elutable antigen detection sampling tube structure according to claim 5, characterized in that, The warning ball (10) is made of iron, and the liquid squeeze sheet (4) is set at an angle.