A sampling device for human stem cell research

Abstract

The utility model discloses a kind of sampling devices for human stem cell research, it includes needle cylinder and needle head installed on needle cylinder, one end of the needle cylinder is movably inserted with push-pull rod, the end portion of push-pull rod inside needle cylinder is fixedly installed with piston, the end portion of push-pull rod outside needle cylinder is fixedly installed with operating handle, the end of needle cylinder surface is fixedly installed with internal thread connecting ring cover, the bottom of internal thread connecting ring cover is threadedly connected with external thread collecting box, collecting port, which is communicated between needle cylinder and internal thread connecting ring cover, is formed in needle cylinder, liftable adjusting circular plate is installed in the inside of external thread collecting box, the top annular of circular plate equidistantly is fixedly installed with several cannula, the inside of cannula is movably inserted with collecting test tube matched with collecting port alignment;The present sampling device has continuous sampling structure, and the performance thereof can meet the use requirement of human stem cell research sampling.

Description

Technical Field

[0001] This utility model belongs to the field of sampling technology, specifically a sampling device for human stem cell research. Background Technology

[0002] Human stem cells are a type of cell with unique potential. They can continuously self-renew and differentiate into various cell types with different functions, such as nerve cells, muscle cells, and blood cells. This multi-directional differentiation ability makes stem cells show great application prospects in the fields of tissue repair, regenerative medicine, and disease treatment. Research on stem cells not only helps us to better understand the mechanisms of life development and disease occurrence, but also provides new hope for overcoming many currently difficult-to-treat diseases.

[0003] Research on stem cells requires the use of sampling equipment. The existing authorized patent (publication number: CN223054491U) is based on a sampling device for human stem cell research. However, this sampling device cannot perform continuous sampling operations, which reduces its performance in actual use. Therefore, improvements are needed to address the above issues. Utility Model Content

[0004] To achieve the above objectives, this utility model provides the following technical solution: a sampling device for human stem cell research, comprising a syringe and a needle mounted on the syringe. A push-pull rod is movably inserted into one end of the syringe. A piston is fixedly installed at the end of the push-pull rod inside the syringe. An operating handle is fixedly installed at the end of the push-pull rod outside the syringe. An internally threaded connecting ring is fixedly installed at one end of the syringe surface. An externally threaded collection box is threadedly connected to the bottom of the internally threaded connecting ring. A collection port communicating between the syringe and the internally threaded connecting ring is opened on the syringe. An adjustable circular plate is installed inside the externally threaded collection box. Several insertion tubes are fixedly installed at equal intervals in a ring on the top of the circular plate. Each insertion tube is movably inserted with a collection test tube that matches and aligns with the collection port.

[0005] Preferably, the interior of the external threaded collection box is provided with a ring plate located at the bottom of the circular plate, and a spring layer is fixedly installed between the bottom of the ring plate and the bottom of the interior of the external threaded collection box.

[0006] Preferably, the bottom of the internal threaded connecting ring cover is fixedly mounted on a sealing ring two that connects with the external threaded collection box, and both the internal threaded connecting ring cover and the external threaded collection box have alignment marks on their surfaces.

[0007] Preferably, an adjusting rod is movably installed through the bottom of the external threaded collection box, the top of the adjusting rod is fixedly connected to the bottom of the circular plate, a first pull ring is fixedly installed at the bottom of the adjusting rod, and an inverted L-shaped limiting rod is fixedly installed at the bottom of the adjusting rod. A plurality of first limiting holes are equidistantly opened in an annular shape at the bottom of the external threaded collection box, and the end of the inverted L-shaped limiting rod is movably inserted into the interior of one of the first limiting holes.

[0008] Preferably, a limit ring is fixedly installed inside the syringe, the push-pull rod has a square structure, and the surface of the push-pull rod is provided with second limit holes at equal intervals, the same number as the number of test tubes collected.

[0009] Preferably, a fixing block is fixedly installed at one end of the syringe, a cross-shaped limiting pin is movably inserted into the middle of the fixing block, the bottom of the cross-shaped limiting pin is connected to the push-pull rod, and a second pull ring is fixedly installed at the top of the push-pull rod. A compression spring is sleeved in the middle of the cross-shaped limiting pin.

[0010] Compared with the prior art, the beneficial effects of this utility model are as follows: This sampling device has a continuous sampling structure, which can improve the efficiency and quantity of sampling. At the same time, the continuous sampling structure has a simple design, is easy to use and operate, and provides stable and reliable sampling. Its performance can meet the sampling needs of human stem cell research. Attached Figure Description

[0011] The accompanying drawings are provided to further understand the present invention and form part of the specification. They are used together with the embodiments of the present invention to explain the present invention and do not constitute a limitation thereof.

[0012] In the attached diagram: Figure 1 This is a front view structural diagram of the sampling device for human stem cell research according to this utility model; Figure 2 This is a cross-sectional view of the sampling device for human stem cell research according to this utility model. Figure 3 This utility model Figure 2 Schematic diagram of local structure Figure 1 ; Figure 4 This utility model Figure 2 Schematic diagram of local structure Figure 2 ; In the diagram: 1. Syringe; 2. Needle; 3. Push-pull rod; 4. Piston; 5. Operating handle; 6. Internal threaded connecting ring cover; 7. External threaded collection box; 8. Collection port; 9. Round plate; 10. Insertion tube; 11. Collection test tube; 12. Ring plate; 1201. Spring layer; 13. Adjusting rod; 14. First pull ring; 15. Inverted L-shaped limiting rod; 16. First limiting hole; 17. Sealing ring II; 18. Alignment mark; 19. Limiting retaining ring; 20. Second limiting hole; 21. Fixing block; 22. Cross-shaped limiting pin; 23. Second pull ring; 24. Compression spring. Detailed Implementation

[0013] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of the present utility model without creative effort are within the protection scope of the present utility model.

[0014] Depend on Figures 1 to 4 The present invention includes a syringe 1 and a needle 2 mounted on the syringe 1. A push-pull rod 3 is movably inserted into one end of the syringe 1. A piston 4 is fixedly installed at the end of the push-pull rod 3 inside the syringe 1. An operating handle 5 is fixedly installed at the end of the push-pull rod 3 outside the syringe 1. An internal threaded connecting ring cover 6 is fixedly installed at one end of the surface of the syringe 1. An external threaded collection box 7 is threadedly connected to the bottom of the internal threaded connecting ring cover 6. A collection port 8 is opened on the syringe 1, connecting the syringe 1 and the internal threaded connecting ring cover 6. An adjustable circular plate 9 is installed inside the external threaded collection box 7. Several insertion tubes 10 are fixedly installed at equal intervals in a ring on the top of the circular plate 9. Each insertion tube 10 is movably inserted into a collection test tube 11 that matches and aligns with the collection port 8. A sealing ring 1 is provided at the bottom of the collection port 8, which contacts the top of the collection test tube 11 for sealing. The rotation trajectory of the insertion tubes 10 on the top of the circular plate 9 is aligned with the collection port 8.

[0015] This sampling device features a continuous sampling structure, which improves sampling efficiency and quantity. Furthermore, the continuous sampling structure is simple in design, easy to use, convenient to operate, and provides stable and reliable sampling. Its performance meets the requirements for sampling in human stem cell research.

[0016] The internal structure of the externally threaded collection box 7 includes a ring plate 12 located at the bottom of the circular plate 9. A spring layer 1201 is fixedly installed between the bottom of the ring plate 12 and the bottom of the internal structure of the externally threaded collection box 7. Figure 3When the middle spring layer 1201 is in a compressed state, the elastic restoring force of the spring layer 1201 will make the collection tube 11 effectively and reliably contact the bottom of the collection port 8. At the same time, the sealing ring at the bottom of the collection port 8 contacts the top of the collection tube 11, thereby effectively ensuring the sealing performance.

[0017] The bottom of the internal thread connecting ring cover 6 is fixedly installed with a sealing ring 17 that connects with the external thread collection box 7. At the same time, both the internal thread connecting ring cover 6 and the external thread collection box 7 have alignment marks 18 on their surfaces. This allows either the internal thread connecting ring cover 6 and the external thread collection box 7 to be aligned with the collection port 8 after they are connected by aligning the two alignment marks 18.

[0018] An adjusting rod 13 is movably installed through the bottom of the external threaded collection box 7. Limiting blocks are fixedly installed on both the inner and outer surfaces of the adjusting rod 13. The top of the adjusting rod 13 is fixedly connected to the bottom of the circular plate 9. A first pull ring 14 is fixedly installed at the bottom of the adjusting rod 13, and an inverted L-shaped limiting rod 15 is fixedly installed at the bottom of the adjusting rod 13. The inverted L-shaped limiting rod 15 is aligned with one of the insertion tubes 10. Several first limiting holes 16 are equidistantly opened in a ring at the bottom of the external threaded collection box 7. The end of the inverted L-shaped limiting rod 15 is movably inserted into the interior of one of the first limiting holes 16. The several first limiting holes 16 are aligned with several insertion tubes 10, thereby enabling precise adjustment of the position of the collection tube 11, so that the collection tube 11 can accurately connect with the collection port 8 to collect the sample.

[0019] Specifically, by operating the handle 5 to pull the push rod 3, the piston 4 is moved. The movement of the piston 4 will enable the needle 2 to effectively draw up the sample, and then the sample enters the inside of the collection tube 11 through the collection port 8. At this time, the adjustment rod 13 is pulled down by the first pull ring 14. The downward movement of the adjustment rod 13 will drive the inverted L-shaped limiting rod 15 and the circular plate 9 to move down, so that the inverted L-shaped limiting rod 15 moves out from the inside of the first limiting hole 16, and the downward movement of the circular plate 9 will drive the insertion tube 10 and the collection tube 11 to move down and compress the spring layer 1201 through the ring plate 12. Then, by rotating the adjusting rod 13 through the first pull ring 14, the adjusting rod 13 drives the circular plate 9, the insertion tube 10, the collection tube 11 and the inverted L-shaped limiting rod 15 to rotate, thereby adjusting the position of the collection tube 11. Finally, the inverted L-shaped limiting rod 15 rotates and is inserted into the next first limiting hole 16 by the elastic restoring force of the spring layer 1201. When the inverted L-shaped limiting rod 15 is inserted into the first limiting hole 16, it will drive the adjusting rod 13, the circular plate 9, the insertion tube 10 and the collection tube 11 to move upward, so that another new collection tube 11 abuts against the bottom of the collection port 8. Then, the sampling operation can be performed again by repeating the above sampling and pulling steps, and continuous sampling operation can be achieved by repeating the above steps.

[0020] The syringe 1 is fixedly installed with a limiting ring 19 inside. The push-pull rod 3 has a square structure, and the surface of the push-pull rod 3 is provided with second limiting holes 20 at equal intervals, the same number as the number of collection tubes 11. A fixing block 21 is fixedly installed at one end of the syringe 1. A cross-shaped limiting pin 22 is movably inserted into the middle of the fixing block 21. The bottom of the cross-shaped limiting pin 22 is connected to the push-pull rod 3, and a second pull ring 23 is fixedly installed at the top of the push-pull rod 3. A compression spring 24 is sleeved in the middle of the cross-shaped limiting pin 22. In the attached figure, the compression spring 24 is in a compressed state, so that the movement of the push-pull rod 3 can be effectively controlled in a single sampling operation. Specifically, when the piston 4 is moved for the first time by pulling the push-pull rod 3 using the operating handle 5, the spring force of the compression spring 24 will cause the bottom of the cross-shaped limiting pin 22 to insert into the first second limiting hole 20, thus completing a single sampling operation. When the push-pull rod 3 is pulled using the operating handle 5 to perform a second sampling operation, the cross-shaped limiting pin 22 needs to be lifted by the second pull ring 23 and the compression spring 24 needs to be compressed. The bottom of the cross-shaped limiting pin 22 will move out of the first second limiting hole 20. Then, the push-pull rod 3 is pulled to make the cross-shaped limiting pin 22 contact the surface of the push-pull rod 3. After that, the spring force of the compression spring 24 will cause the bottom of the cross-shaped limiting pin 22 to insert into the second second limiting hole 20, thus completing the second sampling operation. By repeating the above steps, sampling operations can be performed continuously.

Claims

1. A sampling device for human stem cell research, comprising a syringe (1) and a needle (2) mounted on the syringe (1), characterized in that: A push-pull rod (3) is movably inserted into one end of the syringe (1). A piston (4) is fixedly installed at the end of the push-pull rod (3) inside the syringe (1). An operating handle (5) is fixedly installed at the end of the push-pull rod (3) outside the syringe (1). An internal threaded connecting ring cover (6) is fixedly installed at one end of the surface of the syringe (1). An external threaded collection box (7) is threadedly connected to the bottom of the internal threaded connecting ring cover (6). A collection port (8) is opened on the syringe (1) connecting the syringe (1) and the internal threaded connecting ring cover (6). An adjustable circular plate (9) is installed inside the external threaded collection box (7). Several insertion tubes (10) are fixedly installed at equal intervals in a ring on the top of the circular plate (9). A collection test tube (11) that matches and aligns with the collection port (8) is movably inserted into the inside of each insertion tube (10).

2. The sampling device for human stem cell research according to claim 1, characterized in that: The interior of the external threaded collection box (7) is provided with a ring plate (12) located at the bottom of the circular plate (9), and a spring layer (1201) is fixedly installed between the bottom of the ring plate (12) and the bottom of the interior of the external threaded collection box (7).

3. The sampling device for human stem cell research according to claim 1, characterized in that: The bottom of the internal threaded connecting ring cover (6) is fixedly mounted on a sealing ring two (17) that connects with the external threaded collection box (7). At the same time, both the internal threaded connecting ring cover (6) and the external threaded collection box (7) have alignment marks (18).

4. A sampling device for human stem cell research according to claim 1, characterized in that: An adjusting rod (13) is movably installed through the bottom of the external threaded collection box (7). The top of the adjusting rod (13) is fixedly connected to the bottom of the circular plate (9). A first pull ring (14) is fixedly installed at the bottom of the adjusting rod (13), and an inverted L-shaped limiting rod (15) is fixedly installed at the bottom of the adjusting rod (13). Several first limiting holes (16) are opened at equal intervals in an annular shape at the bottom of the external threaded collection box (7). The end of the inverted L-shaped limiting rod (15) is movably inserted into the interior of one of the first limiting holes (16).

5. A sampling device for human stem cell research according to claim 1, characterized in that: The syringe (1) is fixedly installed with a limiting ring (19), the push-pull rod (3) is a square structure, and the surface of the push-pull rod (3) is provided with the same number of second limiting holes (20) as the number of collection test tubes (11).

6. A sampling device for human stem cell research according to claim 5, characterized in that: One end of the syringe (1) is fixedly installed with a fixing block (21), and a cross-shaped limiting pin (22) is movably inserted into the middle of the fixing block (21). The bottom of the cross-shaped limiting pin (22) is connected to the push-pull rod (3), and a second pull ring (23) is fixedly installed on the top of the push-pull rod (3). A compression spring (24) is sleeved in the middle of the cross-shaped limiting pin (22).

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