A virus culture device based on vaccine production

CN224901334UActive Publication Date: 2026-10-27青海生物药品厂有限公司
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Patent Information

Application Number
CN202522597128.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-12-08
Publication Date
2026-10-27
Estimated Expiration
2035-12-08

AI Technical Summary

Technical Problem

[0004]现有技术中的基于疫苗生产的病毒培养装置,在打开培养装置,取其内部的其中一个培养管时,大量的空气会进入到培养装置的内部,存在病毒培养过程中空气中细菌进入到培养装置会对病毒培养造成影响的问题

Benefits of technology

[0014]1、本实用新型通过取料组件,能够在将培养器内部的病毒培养管取出时,不会使大量的空气进入到培养器的内部,进而能够避免在病毒培养过程中大量的空气进入到培养器的内部,影响对病毒培养的问题。

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Abstract

The utility model relates to a virus culture device based on vaccine production, including incubator and virus culture tube, the inside of incubator is provided with taking out assembly, and taking out assembly includes sealed pipe, sealing cover, rotating seat and motor no.
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Description

Technical Field

[0001] This utility model relates to the field of vaccine production technology, and in particular to a virus culture device for vaccine production. Background Technology

[0002] Virus culture devices in vaccine production are the core equipment used to amplify viruses. These viruses then undergo processes such as inactivation, attenuation, or purification to ultimately produce vaccines. They provide a controlled, sterile, and amplifying environment for the viruses.

[0003] Existing virus culture devices for vaccine production have the following drawbacks when used:

[0004] In existing virus culture devices for vaccine production, when the device is opened and one of the culture tubes is taken out, a large amount of air enters the device, posing a problem that airborne bacteria can enter the device and affect the virus culture process. Utility Model Content

[0005] In view of the technical problem in the existing virus culture device based on vaccine production, when the culture device is opened and one of the culture tubes is taken out, a large amount of air will enter the interior of the culture device, which poses a technical problem that the entry of airborne bacteria into the culture device during the virus culture process will affect the virus culture. This utility model provides a virus culture device based on vaccine production.

[0006] The technical solution adopted by this utility model is as follows: a virus culture device for vaccine production, including a culture vessel and virus culture tubes. The culture vessel is equipped with a material handling component, which includes a sealing tube, a sealing cap, a rotating seat, and a motor. The sealing tube is fixedly installed on the inner wall of the top of the culture vessel, and the sealing cap is snapped onto the top of the culture vessel. A sealing ring that fits against the sealing cap is provided on the inner wall of the sealing tube. The rotating seat is rotatably connected to the inside of the culture vessel. The motor is fixedly installed on the outer wall of the bottom of the culture vessel, and the bottom of the rotating seat is connected to the output shaft of the motor. A placement seat is placed on the top of the rotating seat. A lifting sleeve and a limiting sleeve are fixedly installed on the outer wall of the bottom of the placement seat. A second motor is fixedly installed on the outer wall of the bottom of the rotating seat, and a lead screw is provided on the output shaft of the second motor. The lifting sleeve is threaded onto the outside of the lead screw. A limiting rod is fixedly installed on the inner wall of the bottom of the rotating seat, and the limiting sleeve is slidably fitted onto the outside of the limiting rod. The virus culture tubes are inserted into the inside of the placement seat.

[0007] Furthermore, the placement seat is provided with a fixing component inside, which includes a cavity, a movable plate, a fixing plate and a lifting ring, with the cavity located inside the placement seat.

[0008] Furthermore, the movable plate is slidably connected inside the cavity, and a spring connected to the movable plate is provided inside the cavity.

[0009] Furthermore, a connecting rod connected to the fixed plate is fixedly installed on the outer wall of the movable plate, and a protective pad is provided on the outer wall of the fixed plate.

[0010] Furthermore, the lifting ring is located at the top of the placement seat, and a long rod that is inserted into the cavity is provided on the outer wall of the bottom of the lifting ring.

[0011] Furthermore, a compression block is provided at the bottom end of the long rod, and a second spring connected to the compression block is provided inside the cavity, with the second spring sleeved on the outside of the long rod.

[0012] Furthermore, the outer wall of the incubator is provided with an installation groove, and the interior of the installation groove is provided with a ventilation mesh.

[0013] The beneficial effects of this utility model are:

[0014] 1. This utility model, through its material handling component, prevents a large amount of air from entering the interior of the incubator when removing the virus culture tubes from inside the incubator. This avoids the problem of a large amount of air entering the interior of the incubator during the virus culture process, which could affect the virus culture.

[0015] 2. Secondly, this utility model uses a fixing component to insert the virus culture tube into the placement base. When fixing the virus culture tube with the fixing component, the operation is more convenient, and it can fix virus culture tubes of different diameters, making the application range wider. Attached Figure Description

[0016] Figure 1 This is a three-dimensional view of the entire utility model;

[0017] Figure 2 This is an internal sectional perspective view of the present invention;

[0018] Figure 3 This is a perspective view of the lead screw, lifting sleeve, limiting rod, and limiting sleeve of this utility model;

[0019] Figure 4 This is a perspective view of the fixing component of this utility model.

[0020] The components in the diagram are labeled as follows: 1. Incubator; 2. Feeding assembly; 201. Sealing tube; 202. Sealing cap; 203. Placement seat; 204. Rotating seat; 205. Motor 1; 206. Motor 2; 207. Lead screw; 208. Lifting sleeve; 209. Limiting rod; 210. Limiting sleeve; 211. Sealing ring; 3. Fixing assembly; 301. Cavity; 302. Moving plate; 303. Fixing plate; 304. Protective pad; 305. Spring 1; 306. Long rod; 307. Lifting ring; 308. Spring 2; 309. Squeezing block; 310. Connecting rod; 4. Virus culture tube; 5. Mounting slot; 6. Ventilation net. Detailed Implementation

[0021] In the description of this utility model, it should be noted that the terms "front", "up", "down", "left", "right", "vertical", "horizontal", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0022] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0023] The following is in conjunction with the appendix Figures 1-4 The present invention will be further described below.

[0024] To address the problems existing in the background technology, this application proposes the following technical solution: a virus culture device based on vaccine production.

[0025] The specific technical solution includes a culture vessel 1 and a virus culture tube 4. The culture vessel 1 is internally equipped with a material handling component 2, which includes a sealing tube 201, a sealing cap 202, a rotating seat 204, and a motor 205. The sealing tube 201 is fixedly mounted on the inner wall of the top of the culture vessel 1, and the sealing cap 202 is snapped onto the top of the culture vessel 1. A sealing ring 211 that fits against the sealing cap 202 is provided on the inner wall of the sealing tube 201. The rotating seat 204 is rotatably connected inside the culture vessel 1. The motor 205 is fixedly mounted on the outer wall of the bottom of the culture vessel 1, and the bottom of the rotating seat 204 is connected to the output shaft of the motor 205. A placement seat 203 is placed on the top of the rotating seat 204. A lifting sleeve 208 and a limiting sleeve 210 are fixedly mounted on the outer wall of the bottom of the placement seat 203. A second motor 206 is fixedly installed on the wall, and a lead screw 207 is installed on the output shaft of the second motor 206. A lifting sleeve 208 is threadedly connected to the outside of the lead screw 207. A limit rod 209 is fixedly installed on the inner wall of the bottom of the rotating seat 204, and a limit sleeve 210 is slidably connected to the outside of the limit rod 209. The virus culture tube 4 is inserted into the placement seat 203. The virus culture tube 4 to be removed and the placement seat 203 below can be pushed up through the sealing tube 201, so that when the virus culture tube 4 is removed, the placement seat 203 can be locked in the sealing tube 201. This can prevent a large amount of air from entering the interior of the incubator 1 through the sealing tube 201 when one of the virus culture tubes 4 is removed, thereby preventing a large amount of air from entering the interior of the incubator 1 during the virus culture process and affecting the virus culture.

[0026] In specific implementations, such as Figure 2 and Figure 4 As shown, the placement seat 203 is provided with a fixing component 3 inside. The fixing component 3 includes a cavity 301, a moving plate 302, a fixing plate 303 and a lifting ring 307. The cavity 301 is located inside the placement seat 203.

[0027] Furthermore, the movable plate 302 is slidably connected inside the cavity 301, and the cavity 301 is provided with a spring 305 connected to the movable plate 302. When the movable plate 302 is not squeezed by the squeezing block 309, the elastic force of the spring 305 can push the movable plate 302 to move.

[0028] Furthermore, a connecting rod 310 connected to the fixed plate 303 is fixedly installed on the outer wall of the movable plate 302, and a protective pad 304 is provided on the outer wall of the fixed plate 303. The protective pad 304 can increase the friction between the fixed plate 303 and the outer wall of the virus culture tube 4, so as to fix the virus culture tube 4 more firmly. On the other hand, it can protect the outer wall of the virus culture tube 4.

[0029] Furthermore, the lifting ring 307 is located at the top of the placement seat 203, and a long rod 306 is provided on the outer wall of the bottom of the lifting ring 307, which is inserted into the cavity 301. When the lifting ring 307 is lifted, the long rod 306 and the squeezing block 309 can be pulled upward.

[0030] Furthermore, a pressing block 309 is provided at the bottom end of the long rod 306, and a second spring 308 connected to the pressing block 309 is provided inside the cavity 301. The second spring 308 is sleeved on the outside of the long rod 306, and the elastic force of the second spring 308 can push the pressing block 309 to move downward.

[0031] In specific implementations, such as Figure 1 , 2 and Figure 4 As shown, an installation groove 5 is provided on the outer wall of the incubator 1, and a ventilation mesh 6 is provided inside the installation groove 5. The ventilation mesh 6 is used to dissipate heat from the motor 206.

[0032] To ensure that those skilled in the art can fully understand the technical solution, this application provides the following overall overview:

[0033] In use, the motor 206 located directly below the sealing tube 201 is turned on, causing the lead screw 207 to rotate. This causes the lifting sleeve 208 outside the lead screw 207 to synchronously raise the placement seat 203 axially outside the lead screw 207, raising the placement seat 203 to its highest position. At this point, the bottom of the placement seat 203 will be wedged between the sealing tubes 201, and the top of the placement seat 203 will be higher than the top of the incubator 1. The lifting ring 307 is then lifted upwards, and the virus culture tube 4 containing the virus is placed in the placement seat 203. Internally, releasing the lifting ring 307 causes the spring force of spring 2 308 to push the squeezing block 309 downward, squeezing the inclined surface of the moving plate 302. This allows the moving plate 302 to move the connecting rod 310 and the fixed plate 303. The two opposing fixed plates 303 can fix virus culture tubes 4 of different diameters, making operation more convenient. Turning on motor 206 drives the lead screw 207 to rotate, causing the lifting sleeve 208 outside the lead screw 207 to synchronously drive the upper placement seat 203 to descend axially outside the lead screw 207. Using the above method, multiple virus culture tubes 4 are fixed in multiple placement seats 203, and the sealing cap 202 is placed on top of the incubator 1. The virus is cultured in the virus culture tubes 4. When it is necessary to remove one of the virus culture tubes 4, motor 1 205 is turned on to drive the rotating seat 204 to rotate, rotating the virus culture tube 4 to be removed to be directly below the sealing tube 201. Motor 2 206 directly below the sealing tube 201 is turned on to drive the lead screw 207 to rotate, which enables the lifting sleeve 2 outside the lead screw 207 to move. 08 synchronously drives the upper placement seat 203 to rise axially outside the lead screw 207. When the top of the placement seat 203 is in contact with the sealing ring 211 inside the sealing tube 201, the sealing cover 202 is opened, and the placement seat 203 is driven to rise again, so that the top of the placement seat 203 is higher than the top of the incubator 1, and the bottom of the placement seat 203 is still in contact with the sealing ring 211. This can avoid the problem of a large amount of air entering the incubator 1 and affecting the virus culture when one of the virus culture tubes 4 is removed.

[0034] All standard parts used in this utility model can be purchased from the market, and irregular parts can be customized according to the description and drawings. The specific connection methods of each part adopt conventional methods such as bolts, rivets, and welding that are mature in the prior art. The machinery, parts and equipment adopt conventional models in the prior art. In addition, the circuit connection adopts conventional connection methods in the prior art, which will not be described in detail here. The contents not described in detail in this specification belong to the prior art known to those skilled in the art.

[0035] Although embodiments of the present invention have been shown and described, the scope of the present invention will be defined by the appended claims and their equivalents for those skilled in the art.

Claims

1. A virus culture device for vaccine production, characterized in that, The system includes a culture vessel (1) and a virus culture tube (4). The culture vessel (1) is equipped with a material handling component (2). The material handling component (2) includes a sealing tube (201), a sealing cap (202), a rotating seat (204), and a motor (205). The sealing tube (201) is fixedly installed on the inner wall of the top of the culture vessel (1), and the sealing cap (202) is snapped onto the top of the culture vessel (1). A sealing ring (211) is provided on the inner wall of the sealing tube (201) to fit against the sealing cap (202). The rotating seat (204) is rotatably connected to the inside of the culture vessel (1). The motor (205) is fixedly installed on the outer wall of the bottom of the culture vessel (1), and the bottom of the rotating seat (204) is connected to the motor. The output shaft of the first (205) is connected, and the top of the rotating seat (204) is placed on the placement seat (203). The outer wall of the bottom of the placement seat (203) is fixedly provided with a lifting sleeve (208) and a limiting sleeve (210). The outer wall of the bottom of the rotating seat (204) is fixedly provided with a second motor (206), and the output shaft of the second motor (206) is provided with a lead screw (207). The lifting sleeve (208) is threaded to the outside of the lead screw (207). The inner wall of the bottom of the rotating seat (204) is fixedly provided with a limiting rod (209), and the limiting sleeve (210) is slidably sleeved on the outside of the limiting rod (209). The virus culture tube (4) is inserted into the inside of the placement seat (203).

2. The virus culture device for vaccine production according to claim 1, characterized in that, The placement seat (203) is provided with a fixing component (3) inside. The fixing component (3) includes a cavity (301), a moving plate (302), a fixing plate (303), and a lifting ring (307). The cavity (301) is located inside the placement seat (203).

3. The virus culture device for vaccine production according to claim 2, characterized in that, The movable plate (302) is slidably connected to the inside of the cavity (301), and the inside of the cavity (301) is provided with a spring (305) connected to the movable plate (302).

4. The virus culture device for vaccine production according to claim 3, characterized in that, A connecting rod (310) connected to a fixed plate (303) is fixedly installed on the outer wall of the movable plate (302), and a protective pad (304) is provided on the outer wall of the fixed plate (303).

5. A virus culture device for vaccine production according to claim 4, characterized in that, The lifting ring (307) is located at the top of the placement seat (203), and a long rod (306) inserted into the cavity (301) is provided on the outer wall of the bottom of the lifting ring (307).

6. A virus culture device for vaccine production according to claim 5, characterized in that, The bottom end of the long rod (306) is provided with a pressing block (309), and the cavity (301) is provided with a second spring (308) connected to the pressing block (309), and the second spring (308) is sleeved on the outside of the long rod (306).

7. A virus culture device for vaccine production according to claim 1, characterized in that, The incubator (1) has an installation groove (5) on its outer wall, and a ventilation mesh (6) is provided inside the installation groove (5).