Drier with crystallization function

Abstract

The application discloses a drying machine with crystallization function and belongs to the technical field of medicine production. Mainly including a tank body with a feeding port and a discharging port, a crystallization mechanism is arranged outside the tank body, the crystallization mechanism comprises a cover shell arranged outside the tank body, a cavity is arranged between the tank body and the cover shell, a jacket is arranged inside the cavity, the jacket divides the cavity into a heating cavity attached to the outside of the tank body and a water return cavity attached to the inside of the cover shell, and a crushing assembly is arranged outside the tank body. The drying machine with crystallization function has the effects of completing the whole process production from crystallization to drying in the same closed equipment, preventing material caking and realizing online quality monitoring by arranging the crystallization mechanism, the crushing assembly and the online sampling valve.

Description

Technical Field

[0001] This application relates to the field of pharmaceutical manufacturing technology, specifically to a dryer with crystallization function. Background Technology

[0002] In the production processes of industries such as pharmaceuticals and fine chemicals, materials typically need to go through four independent process steps to complete the processing: reaction crystallization, solid-liquid separation, washing, and drying.

[0003] Currently, in the chemical and pharmaceutical industries, after material reaction, concentration or crystallization, filtration or centrifugal dehydration, washing, and further filtration or centrifugal dehydration, ordinary double cone rotary vacuum dryers are used for drying.

[0004] For example, the patent with publication number CN202018187U discloses a double cone rotary vacuum dryer. This patent uses the rotary motion of the double cone container in a vacuum environment to make the material continuously turn over and come into contact with the heated wall surface, thereby achieving the drying operation.

[0005] However, the above-mentioned processes involve a large number of unit operation equipment and material transfer devices, which not only have drawbacks such as large production site layout, high equipment installation investment, dispersed operators, and complex material transportation links, limiting the development of large-scale production, but also make the materials in the production process, especially in the production of sterile powder, extremely susceptible to secondary contamination by the environment.

[0006] Therefore, it is necessary to provide a dryer with crystallization function to solve the above problems.

[0007] It should be noted that the information disclosed in this background section is only for understanding the background technology of this application concept, and therefore may include information that does not constitute prior art. Summary of the Invention

[0008] Based on the aforementioned problems in the existing technology, the problem to be solved by this application is: to provide a dryer with crystallization function, which solves the problem that traditional three-in-one drying equipment cannot complete the entire process from crystallization to drying in the same closed system, as well as the problem that materials are prone to agglomeration and cannot be monitored in real time during the process.

[0009] The technical solution adopted by this application to solve its technical problem is: a dryer with crystallization function, including:

[0010] A tank with an inlet and an outlet;

[0011] A crystallization mechanism is disposed on the outside of the tank body, and the crystallization mechanism includes:

[0012] A casing, which is disposed on the outside of the tank body;

[0013] A cavity is provided between the outer side of the tank body and the cover;

[0014] A jacket is disposed inside the cavity;

[0015] Heating chamber, which is attached to the outside of the tank body

[0016] The water return chamber is fitted inside the housing.

[0017] A crushing assembly is disposed on the outside of the tank.

[0018] Furthermore, the heating chamber is connected to the return water chamber, a pipe is provided on the outside of the cover, one end of the pipe is connected to the return water chamber, a heat-conducting pipe is provided inside the pipe, and the heat-conducting pipe is connected to the heating chamber.

[0019] Furthermore, one end of the heat-conducting pipe is provided with a water inlet, and the side of the pipe near the water inlet is provided with a drain outlet.

[0020] Furthermore, the crushing assembly includes a motor fixedly mounted on the outside of the tank, the output end of the motor penetrating the tank and extending into its interior, and a crushing paddle fixedly mounted on the output end.

[0021] Furthermore, a sampling valve is provided at the lower end of the side wall of the tank. The sampling valve is a vacuum online sampling valve, with its input end penetrating through the tank and extending into its interior, and its output end connected to an external vacuum component.

[0022] Furthermore, a filter screen is provided at the input end of the sampling valve.

[0023] Furthermore, there is a filter plate at the bottom of the inside of the tank.

[0024] The beneficial effects of this application are: the dryer with crystallization function provided by this application, by setting up a crystallization mechanism, a crushing component and an online sampling valve, achieves the effect of completing the entire production process from crystallization to drying in the same closed equipment, preventing material agglomeration and realizing online quality monitoring.

[0025] In addition to the purposes, features, and advantages described above, this application has other purposes, features, and advantages. A further detailed description of this application will be provided below with reference to the figures. Attached Figure Description

[0026] The accompanying drawings, which form part of this application, are used to provide a further understanding of this application. The illustrative embodiments and descriptions of this application are used to explain this application and do not constitute an undue limitation of this application. In the drawings:

[0027] Figure 1 This is a cross-sectional schematic diagram of the dryer with crystallization function in this application;

[0028] Figure 2 for Figure 1 A schematic diagram of A in the middle;

[0029] The following are the labeling elements in the figure:

[0030] 1. Support frame; 2. Dryer; 20. Crystallization mechanism; 200. Cover; 201. Heating chamber; 202. Jacket; 203. Return water chamber; 204. Pipe; 205. Drain outlet; 206. Inlet; 207. Cavity; 208. Heat pipe; 21. Crushing assembly; 210. Motor; 211. Crushing paddle; 22. Sampling valve; 23. Tank body; 24. Filter plate. Detailed Implementation

[0031] It should be noted that, unless otherwise specified, the embodiments and features described in this application can be combined with each other. This application will now be described in detail with reference to the accompanying drawings and embodiments.

[0032] To enable those skilled in the art to better understand the present application, the technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present application, and not all embodiments. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative effort should fall within the scope of protection of the present application.

[0033] like Figures 1-2 As shown, this application provides a dryer with crystallization function, which is mainly used in pharmaceutical, fine chemical and other industries where materials need to be crystallized, filtered, washed and dried. Specifically, the dryer includes a support 1 and a dryer 2 set on the upper end of the support 1. The dryer 2 is a three-in-one multi-functional drying device disclosed in publication number CN101307981A. The dryer 2 has a tank 23 with a feed inlet (not shown in the figure) and a discharge outlet (not shown in the figure) to facilitate the feeding and discharging of materials and subsequent drying operations.

[0034] In order to achieve forced cooling and crystallization of materials in the equipment, a crystallization mechanism 20 is provided on the outside of the tank body 23. The crystallization mechanism 20 includes a cover 200 fixedly covering the outside of the tank body 23, so that an annular cavity 207 is formed between the outside of the tank body 23 and the cover 200. In order to enhance the heat exchange effect and separate the medium flow path, a jacket 202 is provided in the cavity 207. The jacket 202 divides the cavity 207 into a heating cavity 201 that is tightly attached to the outside of the tank body 23 and a return water cavity 203 that is attached to the inside of the cover 200.

[0035] It should be noted that the heating chamber 201 and the return water chamber 203 are connected through the through hole on the jacket 202, thereby forming a medium circulation channel;

[0036] Meanwhile, a pipe 204 is fixedly connected to the outside of the cover 200. One end of the pipe 204 is connected to the return water chamber 203, and a heat-conducting pipe 208 is provided inside the pipe 204. The other end of the heat-conducting pipe 208 is connected to the heating chamber 201.

[0037] Furthermore, an inlet 206 is provided at the inlet end of the heat pipe 208 for introducing heat sources such as hot water or steam. At the same time, a drain outlet 205 is provided on the side of the pipe 204 near the inlet 206 for discharging the medium that has completed heat exchange.

[0038] Therefore, when crystallization is required, chilled water is first introduced through the inlet 206. The chilled water enters the heating chamber 201 through the heat pipe 208 and exchanges heat with the material in the tank 23 through the jacket 202, thereby achieving forced cooling of the material, accelerating the cooling and crystallization process, improving crystallization efficiency and ensuring crystal uniformity. The temperature of the chilled water increases after heat exchange and flows into the return water chamber 203. Then it is discharged from the drain outlet 205 through the pipe 204, forming a continuous temperature control cycle. When drying is required, hot water is introduced, and the material is heated and dried through the same path. This allows for flexible switching between cooling and heating functions according to process requirements, significantly improving the process adaptability and production efficiency of the equipment.

[0039] Meanwhile, a sampling valve 22 is provided at the lower end of the side wall of the tank 23. The input end of the sampling valve 22 is connected through the flange and extends into the tank 23. The output end is connected to the external vacuum system. A filter screen (not shown in the figure) is provided inside the sampling valve 22.

[0040] It should be noted that the sampling valve 22 adopts an online vacuum design, which allows operators to extract material samples while maintaining the vacuum state inside the equipment, thereby monitoring the degree of crystallization, purity or dryness in real time to ensure that the product quality meets the requirements.

[0041] Furthermore, a filter plate 24 is detachably installed at the bottom of the tank 23 by bolts. The filter plate 24 adopts a microporous filter membrane structure, which can effectively separate crystals from mother liquor and play a supporting and filtering role in the washing and drying stages. At the same time, the precision of the filter plate 24 can be adjusted according to the material, thereby meeting the process requirements of different materials.

[0042] Meanwhile, a crushing assembly 21 is provided on the side wall of the tank body 23. The crushing assembly 21 includes a motor 210 fixedly installed on the outside of the tank body 23 by a mounting base. The output end of the motor 210 penetrates the side wall of the tank body 23 through a mechanical seal structure and extends into its interior. A crushing paddle 211 is fixedly installed at the output end.

[0043] When the motor 210 starts, it drives the crushing paddle 211 to rotate inside the tank 23, crushing and stirring the agglomerated material, thereby making the material heat up evenly, improving drying efficiency, and enabling subsequent crushing operations. In the crystallization stage, the crushing paddle 211 can also be driven to rotate to promote uniform cooling of the material.

[0044] When crystallization is performed, the reacted liquid is first injected into the tank 23 through the feed inlet. The crystallization mechanism 20 is started to introduce chilled water, and the crushing component 21 is turned on to stir, so that the material can be cooled and crystallized quickly. After crystallization is completed, the position of the tank 23 is switched so that the filter plate 24 is at the bottom for solid-liquid separation.

[0045] Then, washing liquid is introduced for washing, and after separation, hot water is switched and vacuum drying is performed. At the same time, the crushing component 21 continues to work to prevent agglomeration. The material status is monitored in real time through the sampling valve 22. Once the standard is met, the product is discharged from the outlet, thereby avoiding material contamination and safety risks.

[0046] The above description is merely a preferred embodiment of this application and is not intended to limit this application. Various modifications and variations can be made to this application by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this application should be included within the protection scope of this application.

Claims

1. A dryer with crystallization function, comprising a tank (23) having an inlet and an outlet, characterized in that: A crystallization mechanism (20) is disposed on the outside of the tank body (23), the crystallization mechanism (20) comprising: A cover (200) is disposed on the outside of the tank body (23); A cavity (207) is provided between the outer side of the tank body (23) and the cover (200); A jacket (202) is disposed inside the cavity (207); Heating chamber (201) is attached to the outside of the tank body (23); A water return cavity (203) is fitted inside the housing (200); Crushing assembly (21) is disposed on the outside of the tank body (23).

2. The dryer with crystallization function according to claim 1, characterized in that: The heating chamber (201) is connected to the return water chamber (203). A pipe (204) is provided on the outside of the cover (200). One end of the pipe (204) is connected to the return water chamber (203). A heat-conducting pipe (208) is provided inside the pipe (204). The heat-conducting pipe (208) is connected to the heating chamber (201).

3. The dryer with crystallization function according to claim 2, characterized in that: One end of the heat pipe (208) is provided with a water inlet (206), and the pipe (204) is provided with a drain outlet (205) on the side near the water inlet (206).

4. The dryer with crystallization function according to claim 1, characterized in that: The crushing assembly (21) includes a motor (210) fixedly installed on the outside of the tank (23). The output end of the motor (210) passes through the tank (23) and extends into its interior, and a crushing paddle (211) is fixedly installed on the output end.

5. The dryer with crystallization function according to claim 1, characterized in that: A sampling valve (22) is provided at the lower end of the side wall of the tank (23). The sampling valve (22) is a vacuum online sampling valve. Its input end passes through the tank (23) and extends into its interior, and its output end is connected to an external vacuum component.

6. The dryer with crystallization function according to claim 5, characterized in that: The sampling valve (22) is equipped with a filter screen at its input end.

7. The dryer with crystallization function according to claim 1, characterized in that: The filter plate (24) at the bottom of the inside of the tank (23).

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