An incubation antibody slot

Abstract

The utility model relates to biological experiment equipment technical field more specifically, relate to a kind of incubation antibody tank, including rack, rack has the placement groove of adjustable size, incubation box is provided with opening in placement groove, incubation box is formed by folding laboratory sealing film. The size of placement groove and incubation box can be flexibly adjusted according to experimental requirements, suitable for different scale experiments, so that the dosage of antibody is more accurate, reduce waste. At the same time, since antibody tank is made of sealing film, it has hydrophobic effect, a small amount of antibody can be wrapped and infiltrated into the electroblotting membrane, greatly reducing the amount of antibody used, saving experimental cost. Laboratory sealing film is a commonly used experimental consumable, widely used in laboratories, without the need for additional procurement of special materials, low price, greatly reducing the experimental cost. By folding laboratory sealing film to form an incubation box, the manufacturing process is simple, without complex process and equipment, and it is convenient to quickly produce and use in the laboratory.

Description

Technical Field

[0001] This utility model relates to the field of biological experimental equipment technology, and more specifically, to an antibody incubation tank. Background Technology

[0002] Antibody incubation is a common experimental procedure in biological experiments. Traditional antibody incubation methods typically use containers such as plastic petri dishes, culture plates, or homemade glass dishes. However, using these containers for incubation has some drawbacks. For example, plastic petri dishes and culture plates are relatively expensive, and the amount of antibody used during incubation is large, which can easily lead to waste. Homemade glass dishes, on the other hand, have problems such as complex manufacturing processes, high costs, and fragility. More importantly, the size and shape of these containers are fixed, making it difficult to flexibly adjust them according to experimental needs. Utility Model Content

[0003] To overcome the problem that the size of antibody incubation containers in the prior art is difficult to adjust according to experimental needs, this utility model provides an antibody incubation tank with the advantages of low cost, readily available materials, and antibody saving.

[0004] To solve the above-mentioned technical problems, the technical solution adopted by this utility model is: an antibody incubation tank, comprising: a placement rack, the placement rack having a placement slot with an adjustable size, an incubation box with an opening provided in the placement slot, the incubation box being formed by folding laboratory sealing film.

[0005] In the technical solution of this utility model, the incubation box is used to incubate antibodies, and the placement rack is equipped with an adjustment slot for storing the incubation box; the size of the placement slot and the incubation box can be flexibly adjusted according to experimental needs, suitable for experiments of different scales, making the antibody dosage more accurate and reducing unnecessary waste; laboratory sealing film is a commonly used experimental consumable, widely used in laboratories, requiring no additional purchase of special materials, and is inexpensive, greatly reducing experimental costs; by folding the laboratory sealing film to form the incubation box, the manufacturing process is simple, requiring no complex processes and equipment, and is convenient for rapid production and use in the laboratory.

[0006] Furthermore, the placement rack includes a base plate and multiple adjustment plates. The base plate has multiple first positioning slots opened around its periphery along a first direction and a second direction, respectively. Each adjustment plate is detachably connected to the first positioning slot along the first direction and the second direction, and the placement groove is formed between each adjustment plate and the base plate.

[0007] In this design, a placement slot is formed by detachably connecting the adjustment plate and the base plate. Changing the connection position of the adjustment plate can create placement slots of different sizes to accommodate incubation boxes of different sizes, ensuring the stability of the incubation boxes during use and making it suitable for experimental needs of different scales.

[0008] Furthermore, the adjusting plate has multiple second positioning slots along its length, and the adjusting plate arranged along the first direction and the adjusting plate arranged along the second direction have intersecting positions, and the adjusting plates are engaged with each other at the intersecting positions through the second positioning slots.

[0009] In this design, the adjustment plates are connected by a second positioning bayonet, which can fix the position of each adjustment plate and prevent structural interference between adjustment plates in two directions.

[0010] Furthermore, it also includes a wet box capable of storing water, and the shelf is placed inside the wet box.

[0011] The solution utilizes a humidified chamber to provide a humid environment for antibody incubation.

[0012] Furthermore, the wet box includes a box body and a sealing cap, the upper end of the box body is provided with an opening, and the sealing cap is connected to the opening.

[0013] In this design, the wet box can be sealed with a sealing cap to facilitate incubation on a shaker.

[0014] Furthermore, the bottom of the placement rack is provided with support feet, the height of which is higher than the liquid level in the wet box.

[0015] In this design, the support feet allow the rack to be supported inside the wet box, preventing the water inside the wet box from directly contacting the rack.

[0016] Furthermore, the first direction and the second direction are perpendicular to each other, and the placement groove has a rectangular cross-section.

[0017] In this solution, a rectangular cross-section placement slot is provided to facilitate regular adjustment of the slot's dimensions.

[0018] Furthermore, the incubation box is a cuboid that matches the placement slot.

[0019] In this design, the cuboid incubation box is easy to fold.

[0020] Furthermore, the bottom of the incubation box is fixedly connected to the bottom of the placement slot via an adhesive layer.

[0021] In this solution, the incubation box is fixed in the placement slot by an adhesive layer, which improves the stability of the incubation box structure.

[0022] Furthermore, the height of the adjustment plate in the vertical direction is not higher than the height of the incubation box.

[0023] In the design, the height of the incubation box is higher than the height of the adjustment plate to facilitate the placement and removal of the incubation box.

[0024] Compared with the prior art, the beneficial effects of this utility model are: I. The dimensions of the antibody incubation tank and incubation box of this invention can be flexibly adjusted according to experimental needs, making it suitable for experiments of different scales. This allows for more precise antibody dosage and reduces unnecessary waste. Furthermore, because the antibody tank is made of a sealing film with hydrophobic properties, a small amount of antibody can effectively coat and wet the electroporation membrane, greatly reducing antibody usage and saving experimental costs.

[0025] Second, the antibody incubation tank of this utility model uses laboratory sealing film, which is a commonly used laboratory consumable and widely used in laboratories. There is no need to purchase special materials separately, and the price is low, which greatly reduces the experimental cost.

[0026] Third, the antibody incubation tank of this utility model is formed by folding laboratory sealing film to form an incubation box. The manufacturing process is simple, requires no complicated processes and equipment, and is easy to quickly manufacture and use in the laboratory. Attached Figure Description

[0027] Figure 1 This is a schematic diagram of the overall structure of the antibody incubation tank of this utility model; Figure 2 yes Figure 1 The main view; Figure 3 yes Figure 1 Top view; Figure 4 This is a schematic diagram of the overall structure of the antibody incubation tank in Example 2; Figure 5 This is a cross-sectional view of the antibody incubation tank in Example 3.

[0028] In the attached diagram: 1. Placement rack; 11. Base plate; 111. First positioning slot; 12. Adjustment plate; 121. Second positioning slot; 13. Support leg; 14. Placement slot; 2. Incubation box; 3. Wet box; 31. Box body; 32. Sealing cover. Detailed Implementation

[0029] The accompanying drawings are for illustrative purposes only and should not be construed as limiting this patent. To better illustrate this embodiment, some components in the drawings may be omitted, enlarged, or reduced, and do not represent the actual dimensions of the product. It is understandable to those skilled in the art that some well-known structures and their descriptions may be omitted in the drawings. The positional relationships described in the drawings are for illustrative purposes only and should not be construed as limiting this patent.

[0030] In the accompanying drawings of this utility model, the same or similar reference numerals correspond to the same or similar components. In the description of this utility model, it should be understood that if terms such as "upper," "lower," "left," "right," "long," and "short" indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, they are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or component referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, the terms used to describe positional relationships in the drawings are only for illustrative purposes and should not be construed as limiting this patent. For those skilled in the art, the specific meaning of the above terms can be understood according to the specific circumstances.

[0031] The technical solution of this utility model will be further described in detail below through specific embodiments and in conjunction with the accompanying drawings: Example 1 refer to Figures 1 to 3 This embodiment discloses an antibody incubation tank, including a placement rack 1, the placement rack 1 having an adjustable placement slot 14, and an incubation box 2 with an opening inside the placement slot 14, the incubation box 2 being formed by folding laboratory sealing film.

[0032] In this embodiment, the incubation box 2 is used to incubate antibodies, and the rack 1 is equipped with an adjustment slot for storing the incubation box 2. The dimensions of the placement slot 14 and the incubation box 2 can be flexibly adjusted according to experimental needs, making it suitable for experiments of different scales, resulting in more precise antibody dosage and reducing unnecessary waste. Simultaneously, since the antibody slot is made of sealing film, which has a hydrophobic effect, a small amount of antibody can effectively encapsulate and wet the electroporation membrane, greatly reducing the amount of antibody used and saving experimental costs. Laboratory sealing film is a commonly used experimental consumable, widely used in laboratories, requiring no additional special materials, and is inexpensive, significantly reducing experimental costs. By folding the laboratory sealing film to form the incubation box 2, the manufacturing process is simple, requiring no complex processes or equipment, facilitating rapid production and use in the laboratory. The rack 1 stabilizes the structure of the incubation box 2 through the placement slot 14, preventing the incubation box 2 from collapsing.

[0033] Laboratory sealing film, also known as parafilm, is a thin film made of paraffin wax with good extensibility, sealing properties, and hydrophobicity. It fuses together under slight heating or pressure and is suitable for various laboratory containers, such as test tubes and petri dishes. Incubation boxes 2 made with laboratory sealing film prevent excessive antibody solution adhesion to the inner wall of the box during antibody incubation, while allowing more antibody solution to adhere to the hydrophilic NC or PVDF membrane, thus reducing the amount of antibody used and conserving antibody (primary antibody).

[0034] In use, the laboratory sealing film is cut and folded to form the required incubation box shape. The thickness of the laboratory sealing film can be 0.127mm, and its placement in the adjustment groove ensures structural stability and ease of operation. The depth of the folded adjustment groove can be 5mm to 20mm, the width 10mm to 50mm, and the length 50mm to 10mm, which can be adjusted according to experimental needs.

[0035] refer to Figures 1 to 3 The placement rack 1 includes a base plate 11 and multiple adjustment plates 12. Multiple first positioning slots 111 are respectively opened around the periphery of the base plate 11 along the first direction and the second direction. Each adjustment plate 12 is detachably connected to the first positioning slot 111 along the first direction and the second direction, and a placement groove 14 is formed between each adjustment plate 12 and the base plate 11.

[0036] In this embodiment, the adjustment plate 12 is detachably connected to the base plate 11 to form a placement slot 14. Changing the connection position of the adjustment plate 12 can form placement slots 14 of different sizes, so as to place incubation boxes 2 of different sizes, which is suitable for experimental needs of different scales.

[0037] Specifically, the base plate 11 can be a rectangular plate structure with a barrier extending along its four perimeter in the height direction. Multiple vertically opening first positioning slots 111 are distributed along the length of the barrier. Adjustable plates 12 can be connected to the base plate 11 in both horizontal and vertical directions, thereby forming an adjustment groove between the adjustable plates 12 or between the adjustable plates 12 and the barrier. By changing the connection of the adjustable plates 12 to different first positioning slots 111, the size of the adjustment groove can be changed to accommodate incubation boxes 2 of different sizes. Since the incubation box 2 is formed by folding laboratory sealing film, its placement in the adjustment groove ensures structural stability and prevents collapse.

[0038] refer to Figure 1 The adjusting plate 12 has multiple second positioning slots 121 along its length. The adjusting plate 12 arranged along the first direction and the adjusting plate 12 arranged along the second direction have intersecting positions. The adjusting plates 12 are engaged with each other at the intersecting positions through the second positioning slots 121.

[0039] In this embodiment, the adjusting plates 12 are connected by second positioning slots 121, which can fix the position of each adjusting plate 12 and prevent structural interference between the adjusting plates 12 in two directions. Specifically, the adjusting plates 12 have second positioning slots 121 along their length direction, and the second positioning slots 121 of the adjusting plates 12 arranged in the first direction and the second direction are oriented opposite each other. For example, the second positioning slots 121 of the adjusting plates 12 along the first direction open upwards, and the second positioning slots 121 of the adjusting plates 12 along the second direction open downwards, and the positioning slots of the two are engaged with each other. The size of the adjusting plates 12 can cover the length or width of the placement rack 1.

[0040] refer to Figures 1 to 3 The first and second directions are perpendicular to each other, and the placement groove 14 has a rectangular cross-section. In this embodiment, the placement groove 14 with a rectangular cross-section is provided to facilitate regular adjustment of its dimensions. (Reference) Figure 1 The incubation box 2 is a cuboid that matches the placement slot 14. In this embodiment, the cuboid incubation box 2 is easy to fold.

[0041] In this embodiment, the bottom of the incubation box 2 is fixedly connected to the bottom of the placement groove 14 via an adhesive layer. In this embodiment, the adhesive layer fixes the incubation box 2 in the placement groove 14, improving the structural stability of the incubation box 2.

[0042] In practical use, a spray bottle can be used to spray a layer of water mist onto the surface of the adjustment tank. Utilizing the surface tension of the water, the incubation box 2 is connected to the placement tank 14, forming a thin water film as the adhesive layer. Because the laboratory sealing film possesses the excellent properties of solid paraffin, it exhibits good extensibility, sealing properties, and hydrophobicity. By slightly heating the overlapping edges or applying finger pressure, they can be fused together. Therefore, a hairdryer can be used to slightly heat the back of the placement rack 1 to allow the water to evaporate appropriately, and the bottom of the incubation box 2 will soften slightly upon heating. After the temperature drops, the bottom of the incubation box 2 will be fixed to the placement tank 14.

[0043] refer to Figure 2 The height of the adjusting plate 12 in the vertical direction is no higher than the height of the incubation box 2. In this design, the incubation box 2 is relatively high to facilitate its placement and removal. The portion of the incubation box 2 that is higher than the adjusting plate 12 allows for easy handling and placement.

[0044] Example 2 refer to Figures 1 to 4Similar to Embodiment 1, this embodiment discloses an antibody incubation tank including a placement rack 1. The placement rack 1 has an adjustable placement groove 14, and an incubation box 2 with an opening is provided in the placement groove 14. The incubation box 2 is formed by folding laboratory sealing film. The placement rack 1 includes a base plate 11 and multiple adjusting plates 12. Multiple first positioning slots 111 are respectively opened on the periphery of the base plate 11 along a first direction and a second direction. Each adjusting plate 12 is detachably connected to the first positioning slot 111 along the first direction and the second direction, and the placement groove 14 is formed between each adjusting plate 12 and the base plate 11.

[0045] The difference between this embodiment and Embodiment 1 is that, referring to... Figure 4 In this embodiment, multiple adjustment plates 12 are arranged in a cross array on the placement rack 1, and multiple placement slots 14 are formed between the adjustment plates 12. The dimensions of adjacent adjustment plates 12 can be the same or different, so that the dimensions of each placement slot 14 are the same or different, thereby enabling the simultaneous incubation of multiple different types and doses of antibodies.

[0046] Example 3 refer to Figures 1 to 5 Similar to Embodiment 2, this embodiment provides an antibody incubation tank comprising a rack 1 with an adjustable placement slot 14. An incubation box 2 with an opening is disposed within the placement slot 14, and the incubation box 2 is formed by folding laboratory sealing film. The rack 1 includes a base plate 11 and multiple adjusting plates 12. Multiple first positioning slots 111 are respectively formed around the periphery of the base plate 11 along a first direction and a second direction. Each adjusting plate 12 is detachably connected to the first positioning slot 111 along the first direction and the second direction, forming a placement slot 14 between each adjusting plate 12 and the base plate 11.

[0047] The difference between this embodiment and Embodiment 2 is that, referring to... Figure 5 In this embodiment, a humidified chamber 3 capable of storing water is also included, with the rack 1 placed inside the humidified chamber 3. In this design, the humidified chamber 3 provides a humid environment to facilitate antibody incubation. (Reference) Figure 1 The wet chamber 3 includes a body 31 and a sealing cover 32. The upper end of the body 31 has an opening, and the sealing cover 32 is connected to the opening. In this embodiment, the sealing cover 32 can seal the wet chamber 3 so that it can be placed on a shaker for incubation.

[0048] More specifically, the wet box 3 can be made from a food storage container, with a small amount of water added to the bottom, the water level being lower than the height of the rack 1. The wet box 3 can reduce antibody evaporation and external contamination, thus improving the success rate of antibody incubation.

[0049] The bottom of the placement rack 1 is provided with support feet 13, the height of which is higher than the liquid level inside the wet chamber 3. In this embodiment, the support feet 13 support the placement rack 1 inside the wet chamber 3, preventing the water inside the wet chamber 3 from directly contacting the placement rack 1. For example, in this embodiment, the support feet 13 are located at the four corners of the bottom of the placement rack 1, providing stable support for the placement rack 1 and preventing the water inside the wet chamber 3 from directly contacting the incubation box 2.

[0050] Combination Figures 1 to 5 The following describes the usage process of at least one embodiment: Four adjusting plates 12 are fixed to the base plate 11 via the first positioning slot 111, forming a rectangular placement groove 14 between the four adjusting plates 12 and the base plate 11; a laboratory sealing film is cut and folded to form a cuboid incubation box 2, which is placed in the placement groove 14 with an opening at the top; the electroporated NC membrane or PVDF membrane is placed into the incubation box 2, and an appropriate amount of antibody solution is added; then the entire placement rack 1 is placed into the humidified box 3 and the sealing cap 32 is closed to prevent antibody evaporation and external contamination. After incubation, the sealing cap 32 is opened, and the incubation box 2 is removed for subsequent experimental operations. The antibody incubation tank of this embodiment has the advantages of low cost, readily available materials, antibody saving, high flexibility, and simple structure, and is suitable for antibody incubation operations in biological experiments.

[0051] Obviously, the above embodiments of this utility model are merely examples for clearly illustrating this utility model, and are not intended to limit the implementation of this utility model. Those skilled in the art can make other variations or modifications based on the above description. It is neither necessary nor possible to exhaustively describe all embodiments here. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of this utility model should be included within the protection scope of the claims of this utility model.

Claims

1. An antibody incubation tank, characterized in that: Includes a placement rack (1) having a size-adjustable placement slot (14) with an open incubation box (2) inside the placement slot (14), the incubation box (2) being formed by folding laboratory sealing film.

2. The antibody incubation tank according to claim 1, characterized in that: The placement rack (1) includes a base plate (11) and a plurality of adjusting plates (12). The periphery of the base plate (11) is provided with a plurality of first positioning slots (111) along a first direction and a second direction respectively. Each of the adjusting plates (12) is detachably connected to the first positioning slot (111) along the first direction and the second direction respectively. The placement groove (14) is formed between each of the adjusting plates (12) and the base plate (11).

3. The antibody incubation tank according to claim 2, characterized in that: The adjustment plate (12) has multiple second positioning slots (121) along its length. The adjustment plate (12) arranged along the first direction and the adjustment plate (12) arranged along the second direction have intersecting positions. The adjustment plates (12) are engaged with each other at the intersecting positions through the second positioning slots (121).

4. The antibody incubation tank according to claim 1, characterized in that: It also includes a water-storing box (3), and the shelf (1) is placed inside the water-storing box (3).

5. The antibody incubation tank according to claim 4, characterized in that: The wet box (3) includes a box body (31) and a sealing cover (32). The upper end of the box body (31) is provided with an opening, and the sealing cover (32) is connected to the opening.

6. The antibody incubation tank according to claim 4, characterized in that: The bottom of the placement rack (1) is provided with a support foot (13), and the height of the support foot (13) is higher than the liquid level in the wet box (3).

7. The antibody incubation tank according to claim 2, characterized in that: The first direction and the second direction are perpendicular to each other, and the placement groove (14) has a rectangular cross-section.

8. The antibody incubation tank according to claim 7, characterized in that: The incubation box (2) is a cuboid that matches the placement slot (14).

9. The antibody incubation tank according to claim 8, characterized in that: The bottom of the incubation box (2) is fixedly connected to the bottom of the placement slot (14) by an adhesive layer.

10. The antibody incubation tank according to claim 2, characterized in that: The height of the adjustment plate (12) in the vertical direction is not higher than the height of the incubation box (2).

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