A urine protein and urine creatinine combined detection integrated reagent device

Abstract

The application provides a urine protein and urine creatinine combined detection integrated reagent device, relates to the technical field of urine protein and urine creatinine combined detection, and comprises a fixed base. A sliding rod is fixedly installed at the top of the fixed base. A sliding block is slidingly installed outside the sliding rod. A vibration mixing box is fixedly installed at the top of the sliding block. An integrated reagent mixing assembly is arranged. After the placing rack is placed, the first motor can be controlled to start. The first motor can drive the driving shaft and the beating block to rotate. The beating block can beat the vibration mixing box after rotating. The vibration mixing box can slide up and down along the sliding rod after receiving the beating. The spring can reset the vibration mixing box. The vibration can quickly mix the urine and the reagent in the multiple reagent bottles. The device can prevent the manual mixing from being broken when the hand is removed. The device can greatly improve the work efficiency by simultaneously mixing multiple groups. The first motor can be controlled to be turned off after the mixing is completed.

Description

Technical Field

[0001] This utility model relates to the field of combined detection technology of urine protein and urine creatinine, and in particular to an integrated reagent device for combined detection of urine protein and urine creatinine. Background Technology

[0002] In clinical testing and primary healthcare settings, the combined detection of urine protein and creatinine is a core method for diagnosing kidney disease and assessing kidney function. The accuracy of the test results directly depends on three key aspects: "thorough mixing of reagents and samples," "precise positioning during the testing process," and "convenient and efficient result reading." Whether it's batch testing in hospital laboratories or rapid screening in community health service centers, high demands are placed on the automation level, ease of operation, and reliability of the testing equipment.

[0003] Existing integrated reagent devices for the combined detection of urine protein and creatinine require manual handling and repeated inversion of the reagent bottle for mixing. This is not only labor-intensive but also prone to insufficient mixing, leading to uneven color development and affecting the accuracy of the test. In addition, the reagent bottle is easily dropped and broken during manual operation, resulting in sample waste and the risk of cross-contamination. Furthermore, manual operation results in insufficient batch processing capacity. Therefore, we propose an integrated reagent device for the combined detection of urine protein and creatinine. Utility Model Content

[0004] In view of this, this application provides an integrated reagent device for the combined detection of urine protein and urine creatinine, aiming to solve the above-mentioned technical problems.

[0005] To achieve the above objectives, the present invention adopts the following technical solution:

[0006] An integrated reagent device for the combined detection of urine protein and urine creatinine includes a fixed base, a slide rod fixedly installed on the top of the fixed base, a slider slidably installed on the outside of the slide rod, a vibration mixing chamber fixedly installed on the top of the slider, one end of two springs fixedly installed on the top of the fixed base, the other end of the springs fixedly installed on the bottom of the slider, and an integrated reagent mixing assembly provided on the fixed base and the vibration mixing chamber.

[0007] The integrated reagent mixing assembly includes an assembly block, a placement rack, a sliding block, a reagent bottle, a sealing cap, and a locking bolt. The assembly block is fixedly installed on the inner walls of the left and right sides of the vibrating mixing chamber. The placement rack is slidably installed on the inner side of the assembly block via the sliding block. The reagent bottle is placed on the inner side of the placement rack. The sealing cap is threaded onto the top of the reagent bottle. The locking bolt is threaded onto the inner side of the assembly block, and one end of the locking bolt abuts against the sliding block.

[0008] Preferably, a support frame is fixedly installed on the top of the fixed base, and a reagent detection positioning component is provided on the support frame.

[0009] Preferably, the integrated reagent mixing assembly further includes a rubber pad, a pull handle, and a fixing frame. The rubber pad is fixedly installed on the inner side of the placement frame, the pull handle is fixedly installed on the rear side of the placement frame, and the fixing frame is fixedly installed on the top of the assembly block.

[0010] Preferably, an electric telescopic rod is fixedly installed on the top of the fixed frame, a pressure sensor is fixedly installed on the output end of the electric telescopic rod, and a downward pressure limiting plate is fixedly installed on the bottom of the pressure sensor, the downward pressure limiting plate abutting against the sealing cover.

[0011] Preferably, a storage battery is fixedly installed on the top of the fixing frame, the storage battery is electrically connected to the electric telescopic rod, and a pressure value display screen is fixedly installed on the top of the fixing frame.

[0012] Preferably, two fixing plates are fixedly installed on the top of the fixed base, a first motor is fixedly installed on one side of the fixing plate, a drive shaft is fixedly installed on the output end of the first motor, and a striking block is fixedly installed on the outside of the drive shaft. The striking block abuts against the vibrating mixing box.

[0013] Preferably, the reagent detection positioning component includes a second motor, a lead screw, a detection sliding frame, a slide groove, and a slidable color card. The second motor is fixedly installed on the top of the support frame, the lead screw is fixedly installed on the output end of the second motor, the detection sliding frame is threaded on the outside of the lead screw and slidably installed on the inside of the support frame, the slide groove is opened on the top of the detection sliding frame, and the slidable color card is slidably installed on the inside of the slide groove.

[0014] Preferably, the reagent detection positioning component further includes a light absorption sensor and a display screen. The light absorption sensor is fixedly installed on the rear side of the detection sliding frame, and the display screen is fixedly installed on the right side of the support frame.

[0015] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0016] (1) The present invention provides an integrated reagent device for the combined detection of urine protein and urine creatinine. Through the integrated reagent mixing assembly, after the placement rack is placed, the first motor can be started. The first motor can drive the drive shaft and the striking block to rotate. After the striking block rotates, it can strike the vibrating mixing box. After receiving the strike, the vibrating mixing box can slide up and down along the slide bar. The spring can reset the vibrating mixing box. The vibration can quickly mix the urine and reagents in multiple reagent bottles, preventing the situation of manual mixing from slipping and breaking. Moreover, the device can mix multiple groups at the same time, which can greatly improve the work efficiency. After the mixing is completed, the first motor is turned off.

[0017] (2) The present invention provides an integrated reagent device for the combined detection of urine protein and urine creatinine. After the reagent detection positioning component is set up, the first motor is turned off after mixing. The first motor can lock the position of the striking block. The striking block can support the vibrating mixing box and prevent the vibrating mixing box from vibrating when the placement rack is removed. The second motor is controlled to drive the lead screw to rotate. The lead screw can drive the detection sliding frame to move up and down through the threaded engagement. The light absorption sensor can be adjusted according to the position of the reagent bottle. The light absorption sensor can detect the light absorption value. The detection result can be transmitted to the display screen for easy observation by personnel.

[0018] To make the above-mentioned objectives, features and advantages of this application more apparent and understandable, preferred embodiments are described below in detail with reference to the accompanying drawings. Attached Figure Description

[0019] Figure 1 This is a three-dimensional structural schematic diagram of an integrated reagent device for the combined detection of urine protein and urine creatinine proposed in this utility model;

[0020] Figure 2 This is a schematic diagram of a three-dimensional view of a partial structure of an integrated reagent device for the combined detection of urine protein and urine creatinine according to an embodiment of this application;

[0021] Figure 3 A schematic diagram showing a three-dimensional view of a portion of the structure of the pressure limiting plate provided according to an embodiment of this application is shown;

[0022] Figure 4 A schematic diagram showing a partial structure of the reagent detection and positioning component provided according to an embodiment of this application is provided.

[0023] Figure label:

[0024] 1. Integrated reagent mixing assembly; 2. Reagent detection and positioning assembly; 3. Fixed base; 4. Slide bar; 5. Spring; 6. Slider; 7. Vibrating mixing chamber; 8. Support frame; 11. Assembly block; 12. Placement rack; 13. Sliding block; 14. Reagent bottle; 15. Sealing cap; 16. Rubber pad; 17. Pull handle; 18. Fixed frame; 19. Electric telescopic rod; 20. Pressure sensor; 21. Downward limit plate; 22. Battery; 23. Pressure value display screen; 24. Fixed plate; 25. First motor; 26. Drive shaft; 27. Impact block; 28. Locking bolt; 31. Second motor; 32. Lead screw; 33. Detection sliding frame; 34. Slide groove; 35. Sliding color card; 36. Light absorption sensor; 37. Display screen. Detailed Implementation

[0025] To further understand the invention content, features and effects of this utility model, the following embodiments are provided, and detailed descriptions are given below in conjunction with the accompanying drawings;

[0026] The structure of this utility model will now be described in detail with reference to the accompanying drawings.

[0027] refer to Figure 1-4 An integrated reagent device for combined detection of urine protein and urine creatinine includes a fixed base 3, a slide rod 4 fixedly installed on the top of the fixed base 3, a slider 6 slidably installed on the outside of the slide rod 4, a vibration mixing box 7 fixedly installed on the top of the slider 6, one end of two springs 5 ​​fixedly installed on the top of the fixed base 3, the other end of the springs 5 ​​fixedly installed on the bottom of the slider 6, and an integrated reagent mixing assembly 1 is provided on the fixed base 3 and the vibration mixing box 7.

[0028] The integrated reagent mixing assembly 1 includes an assembly block 11, a placement rack 12, a sliding block 13, a reagent bottle 14, a sealing cap 15, and a locking bolt 28. The assembly block 11 is fixedly installed on the inner walls of the left and right sides of the vibrating mixing chamber 7. The placement rack 12 is slidably installed on the inner side of the assembly block 11 through the sliding block 13. The reagent bottle 14 is placed on the inner side of the placement rack 12. The sealing cap 15 is threaded onto the top of the reagent bottle 14. The locking bolt 28 is threaded onto the inner side of the assembly block 11, and one end of the locking bolt 28 abuts against the sliding block 13.

[0029] In this embodiment, a support frame 8 is fixedly installed on the top of the fixed base 3, and a reagent detection positioning component 2 is provided on the support frame 8.

[0030] In this embodiment, the integrated reagent mixing assembly 1 also includes a rubber pad 16, a pull handle 17, and a fixing frame 18. The rubber pad 16 is fixedly installed on the inner side of the placement rack 12, the pull handle 17 is fixedly installed on the rear side of the placement rack 12, and the fixing frame 18 is fixedly installed on the top of the assembly block 11.

[0031] In this embodiment, an electric telescopic rod 19 is fixedly installed on the top of the fixed frame 18, a pressure sensor 20 is fixedly installed on the output end of the electric telescopic rod 19, and a pressure limiting plate 21 is fixedly installed on the bottom of the pressure sensor 20. The pressure limiting plate 21 abuts against the sealing cover 15.

[0032] In this embodiment, a storage battery 22 is fixedly installed on the top of the fixing frame 18. The storage battery 22 is electrically connected to the electric telescopic rod 19. A pressure value display screen 23 is fixedly installed on the top of the fixing frame 18.

[0033] In this embodiment, two fixing plates 24 are fixedly installed on the top of the fixed base 3. A first motor 25 is fixedly installed on one side of the fixing plate 24. A drive shaft 26 is fixedly installed on the output end of the first motor 25. A striking block 27 is fixedly installed on the outside of the drive shaft 26. The striking block 27 abuts against the vibrating mixing box 7. The striking block 27 is made of steel, which is not easily damaged during rotation. The striking block 27 can be locked after the first motor 25 stops. The steel striking block 27 is convenient for supporting the vibrating mixing box 7 and preventing the vibrating mixing box 7 from vibrating when the reagent bottle 14 is picked up.

[0034] In this embodiment, the reagent detection positioning component 2 includes a second motor 31, a lead screw 32, a detection sliding frame 33, a slide groove 34, and a slidable color card 35. The second motor 31 is fixedly installed on the top of the support frame 8, the lead screw 32 is fixedly installed on the output end of the second motor 31, the detection sliding frame 33 is threaded on the outside of the lead screw 32 and slidably installed on the inside of the support frame 8, the slide groove 34 is opened on the top of the detection sliding frame 33, and the slidable color card 35 is slidably installed on the inside of the slide groove 34. The light absorption sensor 36 can detect the light absorption value, and the detection result can be transmitted to the display screen 37 for easy observation by personnel. Personnel can also slide the slidable color card 35 to compare the color of the reagent inside the reagent bottle 14.

[0035] In this embodiment, the reagent detection positioning component 2 further includes a light absorption sensor 36 and a display screen 37. The light absorption sensor 36 is fixedly installed on the rear side of the detection sliding frame 33, and the display screen 37 is fixedly installed on the right side of the support frame 8. The display screen 37 is electrically connected to the light absorption sensor 36, and the detection result of the light absorption sensor 36 can be displayed on the display screen 37.

[0036] The specific operation is as follows: Step 1: Place the reagent and the urine to be tested inside the reagent bottle 14, and seal the reagent bottle 14 with the sealing cap 15. Place multiple reagent bottles 14 inside the placement rack 12. The personnel manually hold the placement rack 12 and align it with the corresponding assembly block 11. Push the placement rack 12 into the assembly block 11 through the sliding block 13. Rotate the locking bolt 28 to lock the sliding block 13 in the correct position. Place multiple placement racks 12 on the assembly block 11 in sequence through the sliding block 13. After placement, control the electric telescopic rod 19 to drive the pressure sensor 20 and the downward pressure limit plate 21 to descend and press down on the reagent bottle 14 to fix it. The pressure sensor 20 can monitor the pressure value to prevent excessive downward pressure from damaging the reagent bottle 14.

[0037] Step 2: After the placement rack 12 is placed, the first motor 25 can be started. The first motor 25 can drive the drive shaft 26 and the striking block 27 to rotate. After the striking block 27 rotates, it can strike the vibrating mixing box 7. After receiving the strike, the vibrating mixing box 7 can slide up and down along the slide bar 4. The spring 5 can reset the vibrating mixing box 7. The vibration can quickly mix the urine and reagents in multiple reagent bottles 14, preventing the mixture from breaking when manually mixed. The device can also mix multiple groups at the same time, which can greatly improve work efficiency. After the mixing is completed, the first motor 25 is turned off.

[0038] Step 3: After mixing is complete, the first motor 25 is turned off. The first motor 25 can lock the position of the striking block 27. The striking block 27 can support the vibrating mixing box 7 to prevent vibration when the placement rack 12 is removed. The second motor 31 is controlled to drive the lead screw 32 to rotate. The lead screw 32 can drive the detection sliding frame 33 to move up and down through the threaded engagement. The light absorption sensor 36 can be adjusted according to the position of the reagent bottle 14. The light absorption sensor 36 can detect the light absorption value. The detection result can be transmitted to the display screen 37 for easy observation. Personnel can slide the color card 35 to compare the color with the reagent inside the reagent bottle 14. The core design of the integrated reagent for the combined detection of urine protein and urine creatinine is "a single reagent system containing dual specific reaction components". Through two independent and non-interfering colorimetric reactions, a color change pattern of "main color superposition characteristic color level" is formed to ensure that the color signals of the two indicators can be distinguished and read. This makes it easy for personnel to detect and analyze the content of urine protein and urine creatinine by color.

[0039] Step 4: After the test and analysis are completed, the personnel can manually rotate multiple locking bolts 28 to release the locking bolts 28 from the sliding block 13 and control the electric telescopic rod 19 to drive the downward limit plate 21 to rise. The personnel can manually hold and pull the handle 17 to pull out the placement rack 12, making it more convenient and faster for the personnel to take and place the reagent bottle 14.

[0040] It should be noted that although embodiments of the present invention have been shown and described, those skilled in the art will understand that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. An integrated reagent device for the combined detection of urine protein and urine creatinine, characterized in that, include: A fixed base (3) is provided, a slide rod (4) is fixedly installed on the top of the fixed base (3), a slider (6) is slidably installed on the outside of the slide rod (4), a vibration mixing box (7) is fixedly installed on the top of the slider (6), one end of two springs (5) is fixedly installed on the top of the fixed base (3), the other end of the springs (5) is fixedly installed on the bottom of the slider (6), and an integrated reagent mixing assembly (1) is provided on the fixed base (3) and the vibration mixing box (7). The integrated reagent mixing assembly (1) includes an assembly block (11), a placement rack (12), a sliding block (13), a reagent bottle (14), a sealing cap (15), and a locking bolt (28). The assembly block (11) is fixedly installed on the inner walls of the left and right sides of the vibrating mixing chamber (7). The placement rack (12) is slidably installed on the inner side of the assembly block (11) via the sliding block (13). The reagent bottle (14) is placed on the inner side of the placement rack (12). The sealing cap (15) is threaded onto the top of the reagent bottle (14). The locking bolt (28) is threaded onto the inner side of the assembly block (11), and one end of the locking bolt (28) abuts against the sliding block (13).

2. The integrated reagent device for combined detection of urine protein and urine creatinine according to claim 1, characterized in that, A support frame (8) is fixedly installed on the top of the fixed base (3), and a reagent detection positioning component (2) is provided on the support frame (8).

3. The integrated reagent device for combined detection of urine protein and urine creatinine according to claim 1, characterized in that, The integrated reagent mixing assembly (1) also includes a rubber pad (16), a pull handle (17), and a fixing frame (18). The rubber pad (16) is fixedly installed on the inner side of the placement frame (12), the pull handle (17) is fixedly installed on the rear side of the placement frame (12), and the fixing frame (18) is fixedly installed on the top of the assembly block (11).

4. The integrated reagent device for combined detection of urine protein and urine creatinine according to claim 3, characterized in that, An electric telescopic rod (19) is fixedly installed on the top of the fixed frame (18). A pressure sensor (20) is fixedly installed at the output end of the electric telescopic rod (19). A pressure limiting plate (21) is fixedly installed at the bottom of the pressure sensor (20). The pressure limiting plate (21) abuts against the sealing cover (15).

5. The integrated reagent device for combined detection of urine protein and urine creatinine according to claim 3, characterized in that, A battery (22) is fixedly installed on the top of the fixed frame (18), and the battery (22) is electrically connected to the electric telescopic rod (19). A pressure value display screen (23) is fixedly installed on the top of the fixed frame (18).

6. The integrated reagent device for combined detection of urine protein and urine creatinine according to claim 3, characterized in that, Two fixing plates (24) are fixedly installed on the top of the fixed base (3). A first motor (25) is fixedly installed on one side of the fixing plate (24). A drive shaft (26) is fixedly installed at the output end of the first motor (25). A striking block (27) is fixedly installed on the outside of the drive shaft (26). The striking block (27) abuts against the vibration mixing box (7).

7. The integrated reagent device for combined detection of urine protein and urine creatinine according to claim 2, characterized in that, The reagent detection positioning component (2) includes a second motor (31), a lead screw (32), a detection sliding frame (33), a slide groove (34), and a slidable color card (35). The second motor (31) is fixedly installed on the top of the support frame (8). The lead screw (32) is fixedly installed on the output end of the second motor (31). The detection sliding frame (33) is threaded on the outside of the lead screw (32) and slidably installed on the inside of the support frame (8). The slide groove (34) is opened on the top of the detection sliding frame (33). The slidable color card (35) is slidably installed on the inside of the slide groove (34).

8. The integrated reagent device for combined detection of urine protein and urine creatinine according to claim 7, characterized in that, The reagent detection positioning component (2) also includes a light absorption sensor (36) and a display screen (37). The light absorption sensor (36) is fixedly installed on the rear side of the detection sliding frame (33), and the display screen (37) is fixedly installed on the right side of the support frame (8).

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