Anus continuous administration device

Abstract

The application relates to the field of drug delivery devices, and discloses an anus continuous drug delivery device, which comprises a shuttle-shaped positioning body, a uniform drug film and a drug storage bag. The uniform drug film is provided with a plurality of drug outlet holes, is sleeved outside the shuttle-shaped positioning body, cooperates with the shuttle-shaped positioning body to form a uniform drug cavity, and all the drug outlet holes are communicated with the uniform drug cavity. The drug storage bag is provided with a drug storage cavity, is connected with the shuttle-shaped positioning body, and is communicated with the uniform drug cavity. When force is applied to the drug storage bag to reduce the volume of the drug storage bag, the ointment in the drug storage bag enters the uniform drug cavity and can be discharged from the drug outlet holes. The application can improve the uniformity of the contact between the ointment and the tissues around the anus, can realize continuous drug delivery, and can improve the treatment effect. During the drug delivery process, the ointment is not easy to adhere to other places and to contaminate clothes.

Description

Technical Field

[0001] This utility model relates to the field of drug delivery devices, and more specifically, to a continuous rectal drug delivery device. Background Technology

[0002] The proctology department specializes in the research and treatment of constipation, anal fissures, anal fistulas, anal abscesses, anal stenosis, hypertrophic anal papillae, perianal eczema, mixed hemorrhoids, internal hemorrhoids, and external hemorrhoids. Its research focuses primarily on diseases occurring in the organs at the end of the digestive tract, specifically in the area 8-12 cm from the anus to the rectum. Treatment of some conditions, such as hemorrhoids, generally involves direct application of medication to the anus, including but not limited to suppositories or ointments. Suppositories are inserted directly into the anus, while ointments are typically squeezed directly into the anus or injected using a syringe.

[0003] The inventors discovered in their research that existing rectal medication methods have at least the following drawbacks:

[0004] Whether the ointment is squeezed directly into the anus or injected into the anus using a syringe, the ointment will accumulate inside the anus. The ointment cannot be evenly adhered to the surface of the tissues around the anus, thus weakening the efficacy of the ointment. In addition, when a large amount of ointment accumulates inside the anus, some of the ointment may leave the anus after the medication is administered and the device is withdrawn, which may cause contamination and make the operation inconvenient. Utility Model Content

[0005] The purpose of this invention includes, for example, providing a continuous anal drug delivery device that can improve the uniformity of contact between the ointment and the tissues around the anus, enable continuous drug delivery, and improve efficacy; the drug delivery device does not need to be removed during the drug delivery process, and the ointment is less likely to adhere to various places or stain clothing.

[0006] The embodiments of this utility model can be implemented as follows:

[0007] In a first aspect, this utility model provides a continuous rectal drug delivery device, comprising a spindle-shaped positioning body, a drug-averaging membrane, and a drug reservoir, wherein:

[0008] The drug-averaging membrane is provided with multiple drug outlet holes. The drug-averaging membrane is sleeved on the spindle-shaped positioning body. The drug-averaging membrane and the spindle-shaped positioning body cooperate to form a drug-averaging cavity. All the drug outlet holes are connected to the drug-averaging cavity. The drug storage bag is provided with a drug storage cavity. The drug storage bag is connected to the spindle-shaped positioning body. The drug storage cavity is connected to the drug-averaging cavity.

[0009] When force is applied to the drug storage sac to reduce its volume, the ointment located in the drug storage sac enters the drug equalization chamber and can be discharged from the drug outlet.

[0010] In an optional embodiment, the spindle-shaped positioning body includes a spindle-shaped body and a limiting arm. The proximal end of the spindle-shaped body is connected to the limiting arm, and the distal end of the spindle-shaped body is used for insertion into the anus. A drug delivery port is provided at the proximal end of the spindle-shaped body. The drug storage sac is connected to the proximal end of the spindle-shaped body, and the drug storage cavity communicates with the drug equalization cavity through the drug delivery port.

[0011] In an optional embodiment, there are two limiting arms, both of which are connected to the spindle-shaped body and distributed on both sides of the spindle-shaped body.

[0012] In an optional embodiment, the limiting arm is provided with an arcuate concave surface for contacting the buttocks.

[0013] In an optional embodiment, there are multiple drug storage chambers, and all of the multiple drug storage chambers are connected to the drug homogenization chamber.

[0014] In an optional embodiment, there are multiple drug storage chambers, which are connected in sequence, and one of the drug storage chambers located on the side is connected to the drug equalization chamber.

[0015] In an optional embodiment, a one-way membrane is provided between any adjacent drug storage chambers, and the one-way membrane only allows the ointment in the drug storage chamber to move toward the drug equalization chamber.

[0016] In an optional embodiment, a pre-disconnection portion is provided between any adjacent drug storage cavities. When force is applied to the drug storage sac, the ointment located in the drug storage cavity is squeezed and destroyed by the pre-disconnection portion, so that a docking hole is formed at the location of the pre-disconnection portion, and the adjacent drug storage cavities are connected through the docking hole.

[0017] In an optional embodiment, the pre-disconnection portion is configured as an isolation membrane.

[0018] In an optional embodiment, the rectal continuous drug delivery device further includes a protective film that is peelably adhered to the outside of the drug-eluting membrane.

[0019] The number of drug outlet holes is multiple, and the multiple drug outlet holes are arranged at intervals. In the direction from the proximal end to the distal end of the spindle-shaped positioning body, the diameter of the multiple drug outlet holes gradually increases.

[0020] The beneficial effects of this utility model embodiment include, for example:

[0021] In summary, the continuous anal drug delivery device provided in this embodiment allows for the insertion of the distal end of the spindle-shaped positioning body into the anus at a suitable depth. Once inserted, the spindle-shaped positioning body is surrounded by the surrounding anal tissue, ensuring high stability and preventing easy withdrawal. Then, force is applied to the drug reservoir, reducing its volume. The ointment within the reservoir enters the equalization chamber, which is thin and allows the ointment to spread evenly within it. The ointment is then discharged through the dispensing hole connected to the equalization chamber, contacting the anal tissue. This ensures uniform coating of the ointment onto the anal tissue, resulting in good contact between the ointment and the tissue. Throughout the treatment process, the spindle-shaped positioning body remains inside the anus, guaranteeing continuous drug delivery and improved efficacy. Attached Figure Description

[0022] To more clearly illustrate the technical solutions of the embodiments of this utility model, the drawings used in the embodiments will be briefly introduced below. It should be understood that the following drawings only show some embodiments of this utility model and should not be regarded as a limitation on the scope. For those skilled in the art, other related drawings can be obtained based on these drawings without creative effort.

[0023] Figure 1 This is a schematic diagram of the rectal continuous drug delivery device of this embodiment;

[0024] Figure 2 This is a schematic diagram of the spindle-shaped positioning body in this embodiment;

[0025] Figure 3 This is a schematic diagram of one state of the drug storage bladder in this embodiment;

[0026] Figure 4 This is a schematic diagram of another state of the drug storage bladder in this embodiment;

[0027] Figure 5 This is a partial cross-sectional schematic diagram of the homogenization membrane in this embodiment.

[0028] icon:

[0029] 001-Equalization chamber; 100-Spindle-shaped positioning body; 110-Spindle-shaped body; 120-Limiting arm; 121-Arc-shaped concave surface; 130-Drug delivery port; 200-Equalization membrane; 210-Drug outlet port; 300-Drug reservoir; 310-Drug reservoir; 311-First chamber; 312-Second chamber; 313-Third chamber; 320-One-way membrane. Detailed Implementation

[0030] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this utility model, and not all embodiments. The components of the embodiments of this utility model described and shown in the accompanying drawings can generally be arranged and designed in various different configurations.

[0031] Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments of the invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention.

[0032] It should be noted that similar labels and letters in the following figures indicate similar items. Therefore, once an item is defined in one figure, it does not need to be further defined and explained in subsequent figures.

[0033] In the description of this utility model, it should be noted that if terms such as "upper," "lower," "inner," or "outer" are used to indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, or the orientation or positional relationship in which the product is usually placed during use, they are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0034] Furthermore, the terms "first" and "second" are used only to distinguish descriptions and should not be interpreted as indicating or implying relative importance.

[0035] It should be noted that, where there is no conflict, the features in the embodiments of this utility model can be combined with each other.

[0036] In existing technologies, suppositories or ointments are typically inserted into the anus to treat conditions such as hemorrhoids. When using ointments, a syringe or the ointment container can be directly inserted into the anus to squeeze out the ointment. However, because the ointment accumulates inside the anus, it is difficult to ensure close contact between the ointment and the anal tissue, resulting in poor treatment efficacy. Furthermore, after the ointment is squeezed out, the delivery device needs to be removed, and some ointment is ejected along with the device, causing waste and resulting in ointment adhering to various surfaces and staining clothing.

[0037] In view of this, the designers have provided a continuous anal drug delivery device that can improve the tightness of the ointment in contact with the tissues around the anus, and can achieve continuous treatment, improve efficacy, and the ointment is less likely to adhere to other parts of the body or stain clothing.

[0038] Please refer to Figures 1-5 This embodiment provides a continuous rectal drug delivery device, including a spindle-shaped positioning body 100, a drug-averaging membrane 200, and a drug reservoir 300, wherein:

[0039] The uniform distribution membrane 200 is provided with multiple drug outlet holes 210. The uniform distribution membrane 200 is sleeved on the outside of the spindle-shaped positioning body 100. The uniform distribution membrane 200 and the spindle-shaped positioning body 100 cooperate to form a uniform distribution cavity 001. All drug outlet holes 210 are connected to the uniform distribution cavity 001. The drug storage bag 300 is provided with a drug storage cavity 310. The drug storage bag 300 is connected to the spindle-shaped positioning body 100. The drug storage cavity 310 is connected to the uniform distribution cavity 001.

[0040] When force is applied to the medicine storage sac 300 to reduce its volume, the ointment located in the medicine storage sac 300 enters the medicine equalization chamber 001 and can be discharged from the medicine outlet 210.

[0041] As described above, the method of using the rectal continuous drug delivery device provided in this embodiment is as follows:

[0042] In use, the distal end of the spindle-shaped positioning body 100 is inserted into the anus. After insertion to a suitable depth, the spindle-shaped positioning body 100 is surrounded by the tissues around the anus, ensuring high stability and preventing it from easily withdrawing. Then, force is applied to the drug reservoir 300, reducing its volume. The ointment inside the reservoir 300 enters the drug distribution chamber 001. The drug distribution chamber 001 is thin, allowing the ointment to spread evenly within it and be discharged through the dispensing hole 210, which communicates with the drug distribution chamber 001, thus contacting the anal tissue. This ensures the ointment is evenly coated on the anal tissue, with good contact between the ointment and the tissue. During treatment, the spindle-shaped positioning body 100 remains inside the anus, ensuring continuous drug delivery and improving efficacy.

[0043] The following embodiments illustrate the details of the rectal continuous drug delivery device of this application by way of example.

[0044] In this embodiment, optionally, the spindle-shaped positioning body 100 includes a spindle-shaped body 110 and two limiting arms 120. The spindle-shaped body 110 has a proximal end and a distal end opposite each other in its length direction, wherein the proximal end is the end closer to the operator, and the distal end is the end inserted into the anus. Both limiting arms 120 are connected to the proximal end of the spindle-shaped body 110, and the two limiting arms 120 are symmetrically arranged about the central axis of the spindle-shaped body 110, and the two limiting arms 120 are located on the same diameter of the cross-sectional circle of the spindle-shaped body 110. In use, the distal end of the spindle-shaped body 110 is inserted into the anus, and the two limiting arms 120 cooperate to contact the patient's buttocks, thereby limiting the insertion depth of the spindle-shaped body 110, reasonably controlling the depth, improving safety, and reducing the difficulty of operation.

[0045] Optionally, a drug delivery hole 130 is provided at the proximal end of the spindle-shaped body 110. One end of the drug delivery hole 130 is located on the proximal end face, and the other end is located on the outer peripheral surface of the spindle-shaped body 110. The drug storage cavity 310 can communicate with the drug equalization cavity 001 through the drug delivery hole 130. It should be understood that the drug delivery hole 130 can be a circular hole, and the number of drug delivery holes 130 can be set as needed. Multiple drug delivery holes 130 can be provided around the spindle-shaped body 110 to facilitate the ointment in the drug storage cavity 310 to enter the drug equalization cavity 001 from different positions, thereby improving the uniformity of ointment distribution.

[0046] Optionally, the limiting arm 120 can be configured as an arc-shaped rod, and the limiting arm 120 can be supported by silicone, providing high comfort when in contact with the skin. The limiting arm 120 has an arc-shaped concave surface 121, which faces the buttocks during use, allowing for close contact with the buttocks, a large contact area, high stability, and good limiting effect.

[0047] It is worth noting that the homogenizing film 200 can wrap around the distal end and outer peripheral surface of the spindle-shaped body 110, and is sealed to the periphery of the proximal end of the spindle-shaped body 110. Two limiting arms 120 are located outside the homogenizing film 200. Thus, the homogenizing film 200 and the spindle-shaped body 110 form a homogenizing cavity 001 with a shape similar to the spindle-shaped body 110. The distance between the homogenizing film 200 and the spindle-shaped body 110 is set between 0.5mm and 1.0mm. The homogenizing cavity 001 has a small thickness, which facilitates the spread of ointment within it. Since one end of the infusion port 130 is located on the outer peripheral surface of the spindle-shaped body 110, the homogenizing film 200 covers the position of the infusion port 130 on the outer peripheral surface of the spindle-shaped body 110, thereby connecting the storage cavity 310 and the homogenizing cavity 001 through the infusion port 130.

[0048] Please combine Figure 5 Furthermore, the number of dispensing orifices is set to multiple, arranged at intervals, and the diameter of the orifices gradually increases from the proximal end to the distal end of the spindle-shaped body. That is, the diameter of the dispensing orifice near the proximal end of the spindle-shaped body is smaller than that of the dispensing orifice near the distal end. Part of the ointment entering the equalization chamber from the drug storage chamber can be discharged from the dispensing orifice near the proximal end, while the remaining ointment can smoothly reach the distal end of the spindle-shaped body and be discharged from the dispensing orifice near the distal end. This results in a wide distribution area of ​​the ointment, a large contact area with the tissue, and good therapeutic effect.

[0049] In this embodiment, optionally, there can be multiple drug storage sacs 300, each with a drug storage cavity 310. Thus, there are multiple drug storage cavities 310, each capable of holding a fixed amount of ointment. The type of ointment can be selected as needed, enabling multiple administrations with adjustable intervals. Furthermore, during administration, the device does not need to be removed from the anus, eliminating the need for repeated insertion and removal, reducing difficulty, and minimizing ointment waste.

[0050] In other embodiments, optionally, the number of drug storage sacs 300 can be one, and each drug storage sac 300 is provided with multiple drug storage chambers 310, which are connected in sequence. One drug storage chamber 310 located on the side is directly connected to the drug distribution chamber 001 through the drug delivery hole 130. For example, in this embodiment, the drug storage sac 300 is provided with three drug storage chambers 310 arranged in sequence. Each drug storage chamber 310 can hold a fixed amount of ointment, which can realize quantitative multiple administration and is convenient to operate.

[0051] In one optional embodiment, a one-way diaphragm 320 is provided between any adjacent drug storage chambers 310. The one-way diaphragm 320 only allows the ointment in the drug storage chamber 310 to move towards the drug leveling chamber 001. In use, the ointment in the drug storage chambers 310 is used sequentially from the direction closest to the spindle-shaped body 110 to the direction furthest from the spindle-shaped body 110. That is, the ointment in the drug storage chamber 310 directly connected to the drug delivery hole 130 is used first, then the ointment in the middle drug storage chamber 310 is used, and finally the ointment in the farthest drug storage chamber 310 is used. When the drug storage sac 300 is squeezed to use the ointment in the middle drug storage chamber 310, due to the design of the one-way diaphragm 320, the ointment will enter the nearby drug storage chamber 310 and will not enter the farthest drug storage chamber 310, ensuring that the ointment can smoothly enter the drug leveling chamber 001 from the nearby drug storage chamber 310 through the drug delivery hole 130. For ease of description, the three drug storage chambers 310 are respectively the first chamber 311, the second chamber 312, and the third chamber 313. The first chamber 311 is directly connected to the drug delivery port 130, the second chamber 312 is connected to the first chamber 311, and the third chamber 313 is connected to the second chamber 312. A one-way diaphragm 320 is provided between the first chamber 311 and the second chamber 312. When the first chamber 311 is squeezed, the one-way diaphragm 320 prevents the ointment in the first chamber 311 from entering the second chamber 312. Similarly, a one-way diaphragm 320 is provided between the second chamber 312 and the third chamber 313. When the second chamber 312 is squeezed, the one-way diaphragm 320 prevents the ointment in the second chamber 312 from entering the third chamber 313.

[0052] Please refer to Figure 3 and Figure 4It should be understood that the one-way diaphragm 320 can be a circular piece. Part of the edge of the one-way diaphragm 320 is sealed to the inner wall of the drug reservoir 300, while the remaining edge is separated from the inner wall of the drug reservoir 300. When force is applied to the drug reservoir 300, causing the ointment in the outer drug reservoir 310 to move towards the inner drug reservoir 310, the one-way diaphragm 320 can be broken open.

[0053] In another optional embodiment, a pre-disconnection section is provided between any adjacent drug storage chambers 310. When force is applied to the drug storage sac 300, the ointment in the drug storage chamber 310 is squeezed and destroyed by the pre-disconnection section, so that a connecting hole is formed at the location of the pre-disconnection section, and the adjacent drug storage chambers 310 are connected through the connecting hole. With this design, when force is applied to the drug storage sac 300, the direction of the force is to push the ointment towards the spindle-shaped body 110, thereby squeezing and destroying the pre-disconnection section at the corresponding position, realizing the delivery of the ointment.

[0054] Optionally, the pre-disconnection section can be configured as an isolation membrane.

[0055] In addition, to avoid accidental pressing of the drug reservoir 300, the drug reservoir 300 can be made into a long strip shape and placed in the groove formed by the buttocks; or, during the administration of the drug, the user should try to keep lying face down to reduce the pressure on the drug reservoir 300.

[0056] In this embodiment, optionally, the rectal continuous drug delivery device also includes a protective film, which is peelably attached to the outside of the drug-averaging membrane 200. In use, the protective film is torn open, and then the spindle-shaped body 110 is inserted into the anus. Due to the design of the protective film, the drug-averaging membrane 200 is not contaminated, improving safety.

[0057] It should be understood that the homogenizing film 200 can be made of polylactic acid film, polycaprolactone film or gelatin film, etc.

[0058] The anal continuous drug delivery device provided in this embodiment can evenly apply the ointment to the tissues around the anus, enabling continuous, timed, and quantitative drug delivery with good therapeutic effect.

[0059] The above description is merely a specific embodiment of this utility model, but the protection scope of this utility model is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in this utility model should be included within the protection scope of this utility model. Therefore, the protection scope of this utility model should be determined by the protection scope of the claims.

Claims

1. A continuous rectal drug delivery device, characterized in that, It includes a spindle-shaped positioning body (100), a drug homogenizing film (200), and a drug reservoir (300), wherein: The drug-averaging membrane (200) is provided with multiple drug outlet holes (210). The drug-averaging membrane (200) is sleeved on the outside of the spindle-shaped positioning body (100). The drug-averaging membrane (200) and the spindle-shaped positioning body (100) cooperate to form a drug-averaging cavity (001). All the drug outlet holes (210) are connected to the drug-averaging cavity (001). The drug storage bag (300) is provided with a drug storage cavity (310). The drug storage bag (300) is connected to the spindle-shaped positioning body (100). The drug storage cavity (310) is connected to the drug-averaging cavity (001). When force is applied to the drug reservoir (300) to reduce its volume, the ointment located in the drug reservoir (300) enters the drug equalization chamber (001) and can be discharged from the drug outlet (210).

2. The rectal continuous drug delivery device according to claim 1, characterized in that: The spindle-shaped positioning body (100) includes a spindle-shaped body (110) and a limiting arm (120). The proximal end of the spindle-shaped body (110) is connected to the limiting arm (120), and the distal end of the spindle-shaped body (110) is used for insertion into the anus. A drug delivery hole (130) is provided at the proximal end of the spindle-shaped body (110). The drug storage sac (300) is connected to the proximal end of the spindle-shaped body (110), and the drug storage cavity (310) is connected to the drug equalization cavity (001) through the drug delivery hole (130).

3. The rectal continuous drug delivery device according to claim 2, characterized in that: There are two limiting arms (120), both of which are connected to the spindle-shaped body (110) and distributed on both sides of the spindle-shaped body (110).

4. The rectal continuous drug delivery device according to claim 2, characterized in that: The limiting arm (120) is provided with an arc-shaped concave surface (121) for contacting the buttocks.

5. The rectal continuous drug delivery device according to any one of claims 1-4, characterized in that: The number of drug storage chambers (310) is multiple, and all of the multiple drug storage chambers (310) are connected to the drug equalization chamber (001).

6. The rectal continuous drug delivery device according to any one of claims 1-4, characterized in that: There are multiple drug storage chambers (310), and the multiple drug storage chambers (310) are connected in sequence. One of the drug storage chambers (310) located on the side is connected to the drug equalization chamber (001).

7. The rectal continuous drug delivery device according to claim 6, characterized in that: A one-way diaphragm (320) is provided between any adjacent drug storage chambers (310), and the one-way diaphragm (320) only allows the ointment in the drug storage chamber (310) to move toward the drug equalization chamber (001).

8. The rectal continuous drug delivery device according to claim 6, characterized in that: A pre-disconnection part is provided between any two adjacent drug storage cavities (310). When force is applied to the drug storage sac (300), the ointment in the drug storage cavity (310) is squeezed and destroyed, so that a docking hole is formed at the location of the pre-disconnection part, and the adjacent drug storage cavities (310) are connected through the docking hole.

9. The rectal continuous drug delivery device according to claim 8, characterized in that: The pre-disconnection section is configured as an isolation membrane.

10. The rectal continuous drug delivery device according to any one of claims 1-4, characterized in that: The number of drug outlet holes is multiple, and the multiple drug outlet holes are arranged at intervals. In the direction from the proximal end to the distal end of the spindle-shaped positioning body, the diameter of the multiple drug outlet holes gradually increases.

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