A rotary evaporator table for producing velames

Abstract

The utility model relates to rotary evaporation platform technical field especially relates to a production is with rotary evaporation platform for using vialamine, including operation platform, the upper end one side fixed mounting of operation platform has the side plate, the surface of side plate is fixedly installed with the adapter sleeve through the support, the adapter sleeve is for the inclined setting, the one end of adapter sleeve inserts and is provided with the distilling flask, the inner wall of adapter sleeve is close to the one end of distilling flask and is equipped with the annular groove no.

Description

Technical Field

[0001] This utility model relates to the field of rotary evaporation table technology, and in particular to a rotary evaporation table for producing vileamine. Background Technology

[0002] Vilelemine is a small molecule compound with potential biological activity. Its structural features include multiple chiral centers and special functional groups. It has shown important research value in the treatment of neurodegenerative diseases, ion channel regulation, or the development of novel antibacterial agents. At present, the synthetic route of vilelemine mainly involves constructing the target skeleton through multi-step organic reactions, which involves the purification of key intermediates and the final separation of the target compound.

[0003] Rotary evaporators, widely used in laboratory and industrial production for concentration and solvent removal, play a crucial role in the conventional production process of velevamine. They are primarily used for the efficient evaporation of organic solvents from the crude product system after the reaction, as well as the initial concentration of the crude product in the organic phase, providing high-concentration feedstock for subsequent crystallization, column chromatography, or recrystallization purification steps, as illustrated by the prior art, Chinese Patent Publication No. "CN207545853U". A vacuum rotary evaporator is provided, comprising a support frame, a rotary evaporation system, a feeding system, a condensation system, a recovery tank, a collection tank, a connector, a lifting platform, a heating water tank, and heating tubes. An industrial control system is also included. The rotary evaporation system includes a rotary evaporation flask and a rotating device. The rotating device is connected to the rotary evaporation flask via an internal transmission and drives the flask to rotate. Multiple rotary evaporation systems are distributed along the side of the connector. Multiple heating water tanks equipped with heating tubes are also provided, corresponding to the rotary evaporation systems. Multiple feeding systems are also provided, corresponding to the rotary evaporation systems. This invention designs multiple rotary evaporation systems with large rotary evaporation flasks, thereby multiplying the amount of liquid to be evaporated and enabling continuous sample feeding, meeting the needs of industrial-scale production. The control system ensures precise operation and ease of use.

[0004] Currently, if rotary evaporation is not used for concentration, the intermediates and final products in the synthesis of vileamine are usually dissolved in high-boiling-point mixed solvents or strongly polar solvents, making the solvent removal rate of traditional non-rotary evaporation methods extremely slow. Furthermore, if the temperature cannot be precisely controlled, for example, conventional heating may exceed the solvent boiling point, causing local overheating and resulting in quality problems in the produced products. Utility Model Content

[0005] The purpose of this invention is to address the aforementioned shortcomings in the existing technology by proposing a rotary evaporation table for producing vileamine.

[0006] To achieve the above objectives, the present invention adopts the following technical solution: Design a rotary evaporator for producing velevamine, including an operating table. A side plate is fixedly installed on one side of the upper end of the operating table. A connecting sleeve is fixedly installed on the surface of the side plate by a bracket. The connecting sleeve is inclined. A distillation flask is inserted into one end of the connecting sleeve. An annular groove is formed on the inner wall of the connecting sleeve near the end of the distillation flask. A sealing ring is filled inside the annular groove. The inner side of the sealing ring is tightly wrapped around the outer wall of the port of the distillation flask. The operating table is also equipped with a condenser. One end of the condenser is inserted into the connecting sleeve on the side away from the distillation flask. The condenser is connected to the distillation flask through the corresponding interface. The connecting sleeve has an annular groove two on the end away from the annular groove one. The interior of the annular groove two is filled with a sealing ring two. The inner side of the sealing ring two is firmly wrapped around the outer wall of the condenser interface.

[0007] Preferably, the condenser is internally filled with a condenser tube, which is spiral-shaped and extends outward through the condenser from the top.

[0008] Preferably, a valve is provided at the upper end of the condenser tube, and the valve core is embedded inside the condenser tube.

[0009] Preferably, the surface of the side plate is also fixedly mounted with a support ring by a bracket. The inner wall of the support ring is a conical structure. The condenser is vertically sleeved on the inner wall of the support ring. A recycling bottle is also threaded onto the lower end of the condenser.

[0010] Preferably, the upper end of the operating table is fixedly mounted with an electric heating pot via a bracket, and one-third of the body of the distillation flask is inserted into the interior of the electric heating pot.

[0011] Preferably, the bottom of the electric pot is provided with a heater, which is a heating wire heat-conducting plate or an electric heating tube.

[0012] Preferably, connecting brackets are fixedly installed on both sides of the outer ring wall of the connecting sleeve, and the same bearing is fixedly installed on the surface of the two connecting brackets through the brackets, and a sleeve is installed inside the bearing with an interference fit.

[0013] Preferably, a miniature cylinder is fixedly inserted through the end of the sleeve. The miniature cylinder has a piston rod for telescopic movement inside, and a squeezing block is fixedly installed at the end of the piston rod. The two squeezing blocks are clamped and fitted to the mouth of the distillation flask.

[0014] Preferably, a motor is fixedly mounted on the surface of the connecting frame located on one side by a bracket. The motor is provided with a rotating shaft for driving, and a drive gear is fixedly mounted on the end of the rotating shaft.

[0015] Preferably, a linkage gear is fixedly sleeved on the outer ring wall of the sleeve, and the drive gear and the linkage gear are meshed with each other.

[0016] The design scheme proposed in this utility model has the following beneficial effects in application: 1. The connecting sleeve of this utility model has two annular grooves inside and is filled with sealing rings, which tightly wrap the distillation flask port and the condenser interface respectively, effectively preventing steam leakage and ensuring that the distillation system operates stably in a closed environment. At the same time, a micro cylinder drives the squeezing block to clamp the mouth of the distillation flask, and the motor drives the sleeve to rotate through the gear set, so that the distillation flask can rotate at a uniform speed when heated. 2. The distillation flask of this utility model is directly connected to the condenser through an inclined connecting sleeve to form a continuous steam channel, avoiding the cumbersome installation problems caused by complex pipe connections. The conical structure inside the support ring vertically fixes the condenser, and the recovery bottle is connected to the bottom by a thread, ensuring that the condensate collection process is safe and reliable. In addition, the electric heating pot and temperature control switch can accurately control the heating temperature, so that the heating area of ​​the distillation flask is concentrated and constant. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the overall front structure of this utility model; Figure 2 This is a front view of the connecting sleeve portion of this utility model; Figure 3 For the present utility model Figure 2 Enlarged view of point A; Figure 4 This is a schematic diagram of the condenser and condenser tube distribution of this utility model; Figure 5 This is a schematic diagram of the bearing and sleeve structure of this utility model.

[0018] In the diagram: 1. Operating table; 11. Side plate; 12. Connecting sleeve; 13. Distillation flask; 14. Annular groove one; 15. Sealing ring one; 16. Condenser; 17. Annular groove two; 18. Sealing ring two; 1001. Condenser tube; 1002. Valve; 2. Support ring; 21. Recovery bottle; 3. Electric hot pot; 31. Heater; 4. Connecting frame; 41. Bearing; 42. Sleeve; 43. Miniature cylinder; 44. Extrusion block; 401. Motor; 402. Drive gear; 403. Linkage gear. Detailed Implementation

[0019] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments.

[0020] Reference Figures 1-5A rotary evaporator for producing vileamine includes an operating table 1. A side plate 11 is fixedly installed on one side of the upper end of the operating table 1. A connecting sleeve 12 is fixedly installed on the surface of the side plate 11 by a bracket. The connecting sleeve 12 is inclined. A distillation flask 13 is inserted into one end of the connecting sleeve 12. An annular groove 14 is formed on the inner wall of the connecting sleeve 12 near the end of the distillation flask 13. A sealing ring 15 is filled inside the annular groove 14. The inner side of the sealing ring 15 is tightly wrapped around the outer wall of the port of the distillation flask 13. The distillation flask 13 can be transitionally connected through the connecting sleeve 12. The sealing ring 15 can seal and strengthen the gap between the connecting sleeve 12 and the distillation flask 13. The operating table 1 is also equipped with a condenser 16. One end of the condenser 16 is inserted into the connecting sleeve 12 on the side away from the distillation flask 13. The condenser 16 is connected to the distillation flask 13 through the corresponding interface. The connecting sleeve 12 has an annular groove 17 on the end away from the first annular groove 14. The interior of the second annular groove 17 is filled with a sealing ring 18. The inner side of the sealing ring 18 is tightly wrapped around the outer wall of the interface of the condenser 16. The condenser 16 and the distillation flask 13 can be connected through the connecting sleeve 12, so that the distilled vapor can enter the condenser 16. The sealing ring 18 can strengthen the seal at the connection between the condenser 16 and the connecting sleeve 12.

[0021] The condenser 16 is filled with a condenser tube 1001, which is spiral. The upper end of the condenser tube 1001 extends outward through the condenser 16, and ice water can be added to the inside of the condenser tube 1001.

[0022] A valve 1002 is provided at the upper end of the condenser tube 1001. The valve core of the valve 1002 is embedded inside the condenser tube 1001. The valve 1002 can control the opening and closing of the condenser tube 1001.

[0023] Among them, the surface of the side plate 11 is also fixedly installed with a support ring 2 by a bracket. The inner wall of the support ring 2 is a conical structure. The condenser 16 is vertically sleeved on the inner wall of the support ring 2. The lower end of the condenser 16 is also threaded with a recovery bottle 21. The support ring 2 can assist in supporting the condenser 16, and the recovery bottle 21 can recover the liquid concentrate formed by condensation.

[0024] The upper end of the operating table 1 is fixedly mounted with an electric heating pot 3 via a bracket. One-third of the body of the distillation flask 13 is inserted into the electric heating pot 3. Water can be added into the electric heating pot 3 so that the water comes into contact with the distillation flask 13.

[0025] The electric heating pot 3 is equipped with a heater 31 at the bottom. The heater 31 is a heating wire, a heat-conducting plate, or a heating tube. The heater 31 is connected to a temperature control switch via a wire. The temperature control switch can be used to control the heater 31 to maintain a constant temperature, thereby heating the water in the electric heating pot 3 and then heating the distillation flask 13.

[0026] Among them, connecting brackets 4 are fixedly installed on both sides of the outer ring wall of the connecting sleeve 12. The same bearing 41 is fixedly installed on the surface of the two connecting brackets 4 through the bracket. The sleeve 42 is installed inside the bearing 41 with interference fit. The sleeve 42 can rotate based on the bearing 41.

[0027] The sleeve 42 has a micro cylinder 43 fixedly attached to its end. The micro cylinder 43 has a piston rod for telescopic movement inside, and a pressing block 44 is fixedly installed at the end of the piston rod. The two pressing blocks 44 clamp and fit against the mouth of the distillation flask 13. A storage battery is embedded inside the micro cylinder 43. An integrated switch for synchronous opening and closing of the two micro cylinders 43 is installed on the sleeve 42. The piston rods of the two micro cylinders 43 can be telescopically extended and retracted at the same time. This allows the distillation flask 13 to be clamped and positioned after docking with the connecting sleeve 12. When the sleeve 42 rotates, it can drive the distillation flask 13 to rotate, thereby achieving rotary evaporation and ensuring uniform heating during the evaporation process.

[0028] Among them, a motor 401 is fixedly mounted on the surface of the connecting frame 4 located on one side by a bracket. The motor 401 is provided with a rotating shaft for driving, and a drive gear 402 is fixedly mounted on the end of the rotating shaft. After the motor 401 is powered on, the rotating shaft can be rotated, and the drive gear 402 will rotate.

[0029] Among them, a linkage gear 403 is fixedly sleeved on the outer ring wall of the sleeve 42, and the drive gear 402 and the linkage gear 403 are meshed and installed with each other. Through the cooperation of the drive gear 402 and the linkage gear 403, the rotation drive of the sleeve 42 based on the bearing 41 can be guaranteed to be stable.

[0030] Working method: The electric heating pot 3 installed on the operating table 1 of this solution can be filled with clean water. About one-third of the body of the distillation flask 13 is inserted into the electric heating pot 3, so that the clean water directly contacts the wall of the distillation flask 13. The heater 31 at the bottom of the electric heating pot 3 adopts the structure of electric heating wire heat conduction plate or electric heating tube, and is controlled by an external temperature control switch to precisely adjust the heating temperature. When the heater 31 is started, the clean water in the electric heating pot 3 gradually heats up, and conducts heat energy to the distillation flask 13, so that the material inside is heated and evaporated. The distillation flask 13 is fixed by the inclined connecting sleeve 12. The annular groove 14 on the inner wall of the connecting sleeve 12 is filled with a sealing ring 15 to ensure the sealing of the connection between the port of the distillation flask 13 and the connecting sleeve 12. The steam generated by evaporation enters the connecting sleeve 12 and flows further to the condenser 16 to achieve a continuous and stable evaporation cycle. One end of the condenser 16 is connected to the distillation flask 13 via a connecting sleeve 12. An annular groove 17 is opened at the end of the connecting sleeve 12 away from the distillation flask 13, and a sealing ring 18 is filled inside to enhance the sealing performance of the condenser 16 interface. A spiral condenser tube 1001 is installed inside the condenser 16, and ice water can be injected inside to enhance the condensation effect. When high-temperature steam enters the condenser 16 from the distillation flask 13, it comes into contact with the low-temperature surface of the condenser tube 1001 and quickly condenses into a liquid. A valve 1002 is set at the upper end of the condenser tube 1001 to control the opening and closing of the tube opening, so as to facilitate the adjustment of the flow of the condensing medium. The condensed liquid concentrate falls along the inner wall of the condenser 16 to the recovery bottle 21 at the end. The recovery bottle 21 is fixed to the condenser 16 by threads, so as to facilitate disassembly and product collection. The support ring 2 vertically supports the condenser 16 with a conical structure to ensure its stability. Connecting brackets 4 are fixed on both sides of the outer ring of the connecting sleeve 12. A sleeve 42 is installed on the sleeve 42 via bearings 41, allowing the sleeve 42 to rotate around the bearings 41. A miniature cylinder 43 is fixed to the end of the sleeve 42, and a pressing block 44 is connected to the end of its piston rod. The two pressing blocks 44 clamp the two sides of the mouth of the distillation flask 13 respectively. The miniature cylinder 43 has a built-in battery and controls the piston rod to extend and retract synchronously through an integrated switch, thereby securing or releasing the distillation flask 13. A motor 401 is installed on one side of the connecting bracket 4, and its shaft is connected to a drive gear 402. The linkage gear 403 on the outer ring of the sleeve 42 meshes with the drive gear 402. When the motor 401 is started, the drive gear 402 drives the linkage gear 403 to rotate, thereby causing the sleeve 42 and the clamped distillation flask 13 to rotate synchronously. This rotation mechanism allows the distillation flask 13 to be heated evenly in the electric heating pot 3, improving the evaporation efficiency. At the same time, the sealing connection is maintained by the sealing ring 15 and the connecting sleeve 12. The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and the inventive concept of the present utility model, should be included within the protection scope of the present utility model.

Claims

1. A rotary evaporation table for producing vileamine, comprising an operating table (1), characterized in that: A side plate (11) is fixedly installed on one side of the upper end of the operating table (1). A connecting sleeve (12) is fixedly installed on the surface of the side plate (11) by a bracket. The connecting sleeve (12) is inclined. A distillation flask (13) is inserted into one end of the connecting sleeve (12). An annular groove (14) is opened on the inner wall of the connecting sleeve (12) near the end of the distillation flask (13). A sealing ring (15) is filled inside the annular groove (14). The inner side of the sealing ring (15) is tightly wrapped around the outer wall of the port of the distillation flask (13). The operating table (1) is also equipped with a condenser (16). One end of the condenser (16) is inserted and connected to the side of the connecting sleeve (12) away from the distillation flask (13). The condenser (16) is connected to the distillation flask (13) through the corresponding interface. The end of the connecting sleeve (12) away from the annular groove one (14) is provided with an annular groove two (17). The interior of the annular groove two (17) is filled with a sealing ring two (18). The inner side of the sealing ring two (18) is tightly wrapped around the outer wall of the interface of the condenser (16).

2. The rotary evaporator for producing vileamine according to claim 1, characterized in that: The condenser (16) is filled with a condenser tube (1001), which is spiral-rotating, and the upper end of the condenser tube (1001) extends outward through the condenser (16).

3. The rotary evaporator for producing vileamine according to claim 2, characterized in that: A valve (1002) is provided at the upper end of the condenser tube (1001), and the valve core of the valve (1002) is embedded inside the condenser tube (1001).

4. The rotary evaporator for producing vileamine according to claim 3, characterized in that: The surface of the side plate (11) is also fixedly installed with a support ring (2) by a bracket. The inner wall of the support ring (2) is a conical structure. The condenser (16) is vertically sleeved on the inner wall of the support ring (2). The lower end of the condenser (16) is also threaded with a recycling bottle (21).

5. A rotary evaporator for producing vileamine according to claim 4, characterized in that: The upper end of the operating table (1) is fixedly mounted with an electric heating pot (3) by a bracket, and one-third of the body of the distillation flask (13) is inserted into the interior of the electric heating pot (3).

6. A rotary evaporator for producing vileamine according to claim 5, characterized in that: The bottom of the electric hot pot (3) is provided with a heater (31), which is a heating wire heat-conducting plate or an electric heating tube.

7. A rotary evaporation table for producing vileamine according to claim 6, characterized in that: Both sides of the outer ring wall of the connecting sleeve (12) are fixedly installed with connecting brackets (4). The surfaces of the two connecting brackets (4) are fixedly installed with the same bearing (41) through the bracket. The bearing (41) is internally fitted with a sleeve (42).

8. A rotary evaporator for producing vileamine according to claim 7, characterized in that: The end of the sleeve (42) is fixed with a miniature cylinder (43). The miniature cylinder (43) is equipped with a piston rod for telescopic movement, and the end of the piston rod is fixed with a squeezing block (44). The two squeezing blocks (44) are clamped and fitted to the mouth of the distillation flask (13).

9. A rotary evaporator for producing vileamine according to claim 8, characterized in that: A motor (401) is fixedly mounted on the surface of the connecting frame (4) located on one side by a bracket. The motor (401) is provided with a rotating shaft for driving, and a drive gear (402) is fixedly mounted on the end of the rotating shaft.

10. A rotary evaporator for producing vileamine according to claim 9, characterized in that: A linkage gear (403) is fixedly sleeved on the outer ring wall of the sleeve (42), and the drive gear (402) and the linkage gear (403) are meshed with each other.

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