Grinding bottle

Abstract

The utility model provides a grinding bottle belongs to mechanical technical field. It solves the problem of the poor grinding effect of the tissue section. The grinding bottle includes bottle body and bottle lid, the inside of bottle lid is positioned with grinding piece, the inside of bottle body is equipped with the grinding piece of block, the outside wall of grinding piece has the movable interval between the inner wall of bottle body, is equipped with a plurality of first grinding protruding on the side of grinding piece to grinding piece, is equipped with a plurality of second grinding protruding on the side of grinding piece to grinding piece. It has better grinding effect and other advantages.

Description

Technical Field

[0001] This utility model belongs to the field of mechanical technology and relates to grinding bottles. Background Technology

[0002] In the field of biological research and experimentation, there is a technique called in vitro cell culture. As the name suggests, this refers to a method of simulating the in vivo environment outside the body to allow cells to survive, grow, reproduce, and maintain their main structures and functions. This technique requires the cutting and grinding of biological tissues and the extraction of the tissues using appropriate extraction solutions. Furthermore, in some pathological examinations and treatments, it is sometimes necessary to cut and grind biological tissues. In either case, the use of grinding bottles is unavoidable for cutting and grinding biological tissues.

[0003] Commonly used grinding bottles consist of a bottle body, a cap, and grinding beads housed within the bottle body. In use, tissue sections are placed into the bottle, along with some grinding beads and extraction liquid. The bottle body is then sealed with the cap, and finally, it is mounted on the rotating disc of a centrifugal grinding device. The centrifugal grinding device is then started. The continuous switching of the rotating disc's speed and direction causes the grinding beads to oscillate at high frequency horizontally within the bottle, thus grinding the tissue sections. This method is similar to that described in a multifunctional pharmaceutical molecular biology experimental specimen grinding device disclosed in patent application number 202110773419.0. However, the grinding beads are spherical, and the so-called grinding is merely achieved by the grinding beads squeezing the tissue sections during high-frequency oscillation; it does not possess true shearing action, thus resulting in poor grinding performance. Utility Model Content

[0004] The purpose of this invention is to address the aforementioned problems in the existing technology by proposing a grinding bottle that solves the problem of poor grinding effect on tissue sections.

[0005] The objective of this utility model can be achieved through the following technical solutions:

[0006] A grinding bottle, comprising a bottle body and a bottle cap, characterized in that a grinding disc is positioned inside the bottle cap, a block-shaped grinding element is provided inside the bottle body, there is a movable gap between the outer wall of the grinding element and the inner peripheral wall of the bottle body, a plurality of first grinding protrusions are provided on the side of the grinding disc facing the grinding element, and a plurality of second grinding protrusions are provided on the side of the grinding element facing the grinding disc.

[0007] To use, open the bottle cap, place the tissue slices into the bottle, add the extraction solution, and then recap the bottle. Next, install the grinding bottle cap-down onto the rotating disc of a centrifugal grinder in the laboratory. The grinding media will fall under its own weight and rest against the tissue slices, which in turn rest against the grinding media. Then, start the centrifugal grinder. By continuously switching the rotation speed and direction of the rotating disc, the grinding media will generate high-frequency oscillations in the horizontal direction within the bottle. Since the grinding media is positioned with the cap, the grinding media effectively creates high-frequency motion relative to the grinding media in the horizontal direction. This allows for repeated grinding of the tissue slices located between the grinding media and the grinding media. The desired components precipitated during grinding dissolve in the extraction solution.

[0008] The grinding method of this grinding bottle is that the grinding disc is fixed, while the grinding element moves at high frequency in the horizontal direction relative to the grinding disc. At the same time, the grinding disc is provided with a first grinding protrusion, and the grinding element is provided with a second grinding protrusion. During the high-frequency movement of the grinding element, the cooperation of the first grinding protrusion and the second grinding protrusion can generate a stronger shearing force on the tissue section, thereby greatly improving the grinding effect.

[0009] In the aforementioned grinding bottle, both the bottle body and the bottle cap are plastic parts. The bottle mouth of the bottle body abuts against the inner top wall of the bottle cap. The inner top wall of the bottle cap has a protruding annular flange. The annular flange is located inside the bottle mouth of the bottle body, and the outer peripheral wall of the annular flange is in contact with the inner peripheral wall of the bottle mouth. The grinding disc is positioned inside the annular flange.

[0010] After the cap is connected to the bottle body, the annular flange is located inside the bottle mouth, and the outer peripheral wall of the annular flange is in contact with the inner peripheral wall of the bottle mouth. Since both the bottle body and the cap are plastic parts, a second sealing position is formed at the connection between the bottle body and the cap, which already has a sealing position. This greatly improves the sealing performance of the grinding bottle during grinding and prevents the leakage of the extract.

[0011] In the aforementioned grinding bottle, the inner end of the annular flange has an inclined guide surface on its outer periphery.

[0012] The outer diameter of the annular flange in its natural state is larger than the inner diameter of the bottle body at the bottle mouth (the natural state here refers to the state after the bottle cap is unscrewed from the bottle body). Therefore, an inclined guide surface is provided on the outer circumference of the inner end of the annular flange. The guide surface can be used to guide the annular flange when it is inserted into the bottle mouth.

[0013] In the aforementioned grinding bottle, the edge of the grinding disc has several notches along the circumferential direction, and the grinding disc forms a support between two adjacent notches. The grinding disc is secured to the inner side of the annular flange by each support.

[0014] The grinding disc is inserted into the annular flange, and the feet on the edge of the grinding disc rest against the inner wall of the annular flange, so that the grinding disc is stuck inside the annular flange. This can form multi-point support to ensure the positioning effect of the grinding disc in the bottle cap.

[0015] In the aforementioned grinding bottle, the grinding element is quartz stone.

[0016] The grinding media is made of quartz, which not only provides sufficient weight but also makes it less susceptible to contamination and less likely to affect tissue sections and extracts.

[0017] In the aforementioned grinding bottle, the outer periphery of the bottle cap is evenly distributed with several insertion teeth.

[0018] The teeth not only prevent slippage when workers twist the bottle cap, but also allow the bottle cap to be inserted into the centrifugal grinding equipment.

[0019] Compared with existing technologies, this grinding bottle has the following advantages:

[0020] 1. A grinding disc with several first grinding protrusions is positioned inside the bottle cap, and a grinding component with several second grinding protrusions is set inside the bottle. The grinding component moves at high frequency in the horizontal direction relative to the grinding disc. During this process, the cooperation of the first grinding protrusions and the second grinding protrusions can generate a stronger shearing force on the tissue slices, thereby greatly improving the grinding effect.

[0021] 2. An annular flange protrudes from the inner top wall of the bottle cap. The grinding disc is positioned inside the annular flange. After the bottle cap is connected to the bottle body, the annular flange is located inside the bottle mouth, and the outer peripheral wall of the annular flange is in contact with the inner peripheral wall of the bottle mouth. In this way, since there is already a sealing position at the connection between the bottle body and the bottle cap, a second sealing position is formed by the contact between the outer peripheral wall of the annular flange and the inner peripheral wall of the bottle mouth. This greatly improves the sealing performance of this grinding bottle during grinding and prevents the leakage of extract. Attached Figure Description

[0022] Figure 1 This is a cross-sectional view of the grinding bottle.

[0023] Figure 2 This is a plan view of the grinding bottle.

[0024] Figure 3 This is a planar schematic diagram of the grinding disc.

[0025] In the figure, 1 is the bottle body; 2 is the bottle cap; 2a is the insert tooth; 2b is the annular flange; 2b1 is the guide surface; 3 is the grinding disc; 3a is the first grinding protrusion; 3b is the notch; 3c is the support leg; 4 is the grinding part; 4a is the second grinding protrusion. Detailed Implementation

[0026] The following are specific embodiments of the present invention, which are described in conjunction with the accompanying drawings. However, the present invention is not limited to these embodiments.

[0027] like Figure 1 and Figure 2 As shown, the grinding bottle includes a bottle body 1 and a cap 2, both made of plastic. The cap 2 is threaded onto the outside of the bottle mouth of the bottle body 1. Several teeth 2a are evenly distributed on the outer periphery of the cap 2. The teeth 2a not only prevent slippage when the operator rotates the cap 2, but also allow the cap 2 to be inserted into a centrifugal grinding device. A grinding disc 3 is positioned inside the cap 2. A circular, block-shaped grinding element 4 is provided inside the bottle body 1. There is a movable gap between the outer wall of the grinding element 4 and the inner wall of the bottle body 1. Several first grinding protrusions 3a are provided on the side of the grinding disc 3 facing the grinding element 4, and several second grinding protrusions 4a are provided on the side of the grinding element 4 facing the grinding disc 3. In this embodiment, the grinding disc 3 is a metal sheet, and the grinding element 4 is quartz.

[0028] Furthermore, such as Figure 1 and Figure 3 As shown, the bottle mouth of the bottle body 1 abuts against the inner top wall of the bottle cap 2. The inner top wall of the bottle cap 2 has a protruding annular flange 2b. The annular flange 2b is located inside the bottle mouth of the bottle body 1, and its outer peripheral wall is in contact with the inner peripheral wall of the bottle mouth to form a seal. The grinding disc 3 is positioned inside the annular flange 2b. In its natural state, the outer diameter of the annular flange 2b is slightly larger than the inner diameter of the bottle body 1 at the bottle mouth (the natural state here refers to the state after the bottle cap 2 is unscrewed from the bottle body 1). The outer peripheral side of the inner end of the annular flange 2b has an inclined guide surface 2b1. The edge of the grinding disc 3 has several notches 3b along its circumferential direction. The grinding disc 3 forms supports 3c between adjacent notches 3b. The grinding disc 3 is secured to the inner side of the annular flange 2b by each support 3c. The outer diameter of the grinding part 4 is smaller than the inner diameter of the annular flange 2b.

[0029] In use, open bottle cap 2, place the tissue slice into bottle body 1, add the extraction solution, and then replace bottle cap 2. Next, install the grinding bottle with bottle cap 2 facing down on the rotating disc of a centrifugal grinding device in the laboratory. The grinding element 4 falls under its own weight and rests against the tissue slice, while the tissue slice rests against the grinding disc 3. Then, start the centrifugal grinding device. By continuously switching the rotation speed and direction of the rotating disc, the grinding element 4 generates high-frequency oscillations in the horizontal direction within bottle body 1. Since the grinding disc 3 is positioned with bottle cap 2, the grinding element 4 is essentially moving at a high frequency relative to the grinding disc 3 in the horizontal direction. This allows for repeated grinding of the tissue slice located between the grinding disc 3 and the grinding element 4. The desired components precipitated during the grinding process dissolve in the extraction solution.

[0030] This grinding bottle has an annular flange 2b protruding from the inner top wall of the cap 2. After the cap 2 is connected to the bottle body 1, the annular flange 2b is located inside the bottle mouth of the bottle body 1, and the outer peripheral wall of the annular flange 2b is in contact with the inner peripheral wall of the bottle mouth. Since both the bottle body 1 and the cap 2 are plastic parts, a second sealing position is formed by the contact between the outer peripheral wall of the annular flange 2b and the inner peripheral wall of the bottle mouth, which greatly improves the sealing performance of this grinding bottle during grinding and prevents the leakage of extract.

[0031] Furthermore, the grinding method of this grinding bottle is that the grinding disc 3 is fixed, while the grinding element 4 moves at high frequency in the horizontal direction relative to the grinding disc 3. At the same time, the grinding disc 3 is provided with a first grinding protrusion 3a, and the grinding element 4 is provided with a second grinding protrusion 4a. During the high-frequency movement of the grinding element 4, the cooperation of the first grinding protrusion 3a and the second grinding protrusion 4a can generate a stronger shearing force on the tissue section, thereby greatly improving the grinding effect.

[0032] The specific embodiments described herein are merely illustrative examples illustrating the spirit of this utility model. Those skilled in the art to which this utility model pertains may make various modifications or additions to the described specific embodiments or use similar methods to substitute them, without departing from the spirit of this utility model or exceeding the scope defined by the appended claims.

Claims

1. A grinding bottle, comprising a bottle body (1) and a bottle cap (2), characterized in that, The bottle cap (2) has a grinding disc (3) positioned inside, and the bottle body (1) has a block-shaped grinding component (4). There is a movable gap between the outer wall of the grinding component (4) and the inner peripheral wall of the bottle body (1). The grinding disc (3) has a number of first grinding protrusions (3a) on the side facing the grinding component (4), and the grinding component (4) has a number of second grinding protrusions (4a) on the side facing the grinding disc (3).

2. The grinding bottle according to claim 1, characterized in that, The bottle body (1) and the bottle cap (2) are both plastic parts. The bottle mouth of the bottle body (1) abuts against the inner top wall of the bottle cap (2). The inner top wall of the bottle cap (2) is provided with an annular flange (2b). The annular flange (2b) is located inside the bottle mouth of the bottle body (1) and the outer peripheral wall of the annular flange (2b) is in contact with the inner peripheral wall of the bottle mouth. The grinding disc (3) is positioned inside the annular flange (2b).

3. The grinding bottle according to claim 2, characterized in that, The inner end of the annular flange (2b) has an inclined guide surface (2b1) on its outer periphery.

4. The grinding bottle according to claim 1, 2, or 3, characterized in that, The grinding disc (3) has several notches (3b) along its circumferential edge. The grinding disc (3) forms a support (3c) between two adjacent notches (3b). The grinding disc (3) is held in place by each support (3c) on the inner side of the annular flange (2b).

5. The grinding bottle according to claim 1, 2, or 3, characterized in that, The grinding part (4) is made of quartz.

6. The grinding bottle according to claim 1, 2, or 3, characterized in that, The bottle cap (2) has several teeth (2a) evenly distributed on its outer periphery.

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