Detection consumables and sample detection apparatus

Abstract

The utility model discloses a kind of detection consumables and sample detection equipment, detection consumables include membrane breaking assembly, detection assembly and adsorption filter element, detection assembly includes sample tube and reaction tube, reaction tube is located at the lower end of sample tube, and first sealing membrane is equipped on reaction tube, sample tube has sample cavity and filter cavity sequentially arranged from top to bottom in it, the cavity wall of filter cavity is opened and is sequentially arranged with liquid storage cavity and waste liquid cavity from top to bottom, the cavity wall of filter cavity is opened and is equipped with the second sealing membrane of sealed liquid outlet hole, liquid inlet hole is communicated with waste liquid cavity, membrane breaking assembly is used to break second sealing membrane in turn, and break first sealing membrane;Adsorption filter element is located in filter cavity and between liquid outlet hole and liquid inlet hole.The detection consumables realize nucleic acid purification treatment to sample, greatly improve nucleic acid purity, reduce impurities in sample, and further improve the accuracy of detection result.

Description

Technical Field

[0001] This utility model belongs to the field of in vitro diagnostic technology, specifically relating to a testing consumable and a sample testing device. Background Technology

[0002] Currently, to prevent dust, particulate matter, and other impurities from the external environment from contaminating the sample solution or testing reagents, integrated testing consumables are typically used for sample collection and testing. During sample testing, the collected sample is first placed into a sample tube, and then the septum between the sample tube and the reaction tube is punctured, allowing the sample solution in the sample tube to flow into the reaction tube and mix with the testing reagents before testing. However, existing testing consumables cannot perform nucleic acid purification processes such as washing and elution on the sample, resulting in impurities still mixed in the submitted sample solution, leading to low nucleic acid purity and reduced accuracy of the test results. Utility Model Content

[0003] In view of the above-mentioned defects or deficiencies, this utility model provides a testing consumable and a sample testing device, aiming to solve the technical problem that existing testing consumables cannot perform nucleic acid purification processing on samples.

[0004] To achieve the above objectives, this utility model provides a testing consumable, which includes: Membrane breaking assembly; The detection assembly includes a sample tube and a reaction tube. The reaction tube is located at the lower end of the sample tube and is provided with a first sealing membrane. The sample tube has a sample chamber and a filter chamber arranged sequentially from top to bottom. The filter chamber has a storage chamber and a waste liquid chamber arranged at intervals from top to bottom in the chamber wall. The filter chamber has an outlet hole and an inlet hole on the chamber wall. The outlet hole communicates with the storage chamber. The filter chamber has a second sealing membrane that seals the outlet hole. The inlet hole communicates with the waste liquid chamber. The membrane breaking assembly is movably disposed in the sample tube and is used to sequentially break the second sealing membrane and puncture the first sealing membrane. The adsorption filter element is located inside the filter chamber and between the liquid outlet and the liquid inlet.

[0005] In this embodiment of the invention, the membrane breaking assembly includes an injection pusher and a puncture column. The injection pusher is movably disposed in the sample chamber and is provided with a membrane breaking blade. The puncture column passes through the adsorption filter element. The injection pusher is used to extend into the filter chamber to make the membrane breaking blade break the second sealing membrane and to push the puncture column to puncture the first sealing membrane.

[0006] In this embodiment of the invention, a third sealing membrane is provided inside the sample tube, which is located between the sample chamber and the filter chamber. The lower end of the injection push rod is provided with a piercing tip for piercing the third sealing membrane.

[0007] In this embodiment of the utility model, the injection push rod includes a push rod section and a piston rod section. The piston rod section is movably disposed in the sample chamber. The lower end of the piston rod section is provided with a membrane-breaking blade and a piercing tip. The piston rod section is provided with a partition guide plate with a placement opening. The push rod section is movably disposed above the piston rod section and passes through the sample tube. The push rod section is used to push the piston rod section into the filter chamber.

[0008] In this embodiment of the utility model, a guide seat is provided in the sample cavity, and the guide seat is spaced below the partition guide plate. A guide channel for the piston rod section to pass through is provided on the guide seat, and the size of the guide channel is gradually reduced from top to bottom.

[0009] In this embodiment of the invention, the upper end of the piercing post is provided with a mating groove for the piercing tip to extend into.

[0010] In this embodiment of the utility model, there are two liquid outlet holes, which are spaced apart from top to bottom on the wall of the filter chamber. The number of liquid storage chambers is the same as the number of liquid outlet holes and they are connected in a one-to-one correspondence. There are also two second sealing membranes, which seal the two liquid outlet holes one-to-one. The membrane breaking component is used to break the two second sealing membranes sequentially from top to bottom.

[0011] In this embodiment of the invention, the waste liquid chamber is provided with absorbent foam.

[0012] In this embodiment of the invention, a mounting groove is provided at the lower end of the sample tube, the mounting groove is connected to the filter chamber, and the reaction tube extends into and is installed in the mounting groove.

[0013] To achieve the above objectives, this utility model also provides a sample testing device, which includes the testing consumables described above.

[0014] Through the above technical solutions, the detection consumables and sample detection equipment provided by this utility model embodiment have the following beneficial effects: In the technical solution of this utility model, when using the testing consumables, the sample is placed into the sample chamber so that the lysis buffer lyses the sample to form a sample solution. The sample solution flows downward from the sample chamber into the filter chamber. When the sample solution flows through the adsorption filter, the adsorption filter adsorbs the nucleic acid in the sample solution onto the filter. The unadsorbed waste liquid flows into the waste liquid chamber from the inlet hole. Then, the membrane breaking component moves downward and sequentially breaks the second sealing membrane and punctures the first sealing membrane, so that the purification solution in the storage chamber flows out from the outlet hole and flows through the adsorption filter. The purification solution mixes with the nucleic acid on the adsorption filter to form a purified sample solution. The first sealing membrane is broken to connect the filter chamber and the reaction tube, so that the purified sample solution can flow from the filter chamber into the reaction tube to mix with the detection reagent. This achieves nucleic acid purification of the sample, greatly improves the nucleic acid purity, reduces impurities in the sample, and thus improves the accuracy of the detection results.

[0015] Other features and advantages of this invention will be described in detail in the following detailed description section. Attached Figure Description

[0016] The accompanying drawings are provided to further illustrate the embodiments of the present invention and form part of the specification. They are used together with the following detailed description to explain the embodiments of the present invention, but do not constitute a limitation thereof. For those skilled in the art, other drawings can be obtained based on the structures shown in these drawings without any inventive effort. In the drawings: Figure 1 This is a schematic diagram of the assembly structure of a testing consumable according to an embodiment of the present invention; Figure 2 This is a cross-sectional structural schematic diagram of a testing consumable according to an embodiment of the present invention; Figure 3 This is an exploded structural diagram of a testing consumable according to an embodiment of the present invention; Figure 4 This is a schematic diagram of the structure of a sample tube in a testing consumable according to an embodiment of the present invention; Figure 5 This is a schematic diagram of the structure of the membrane breaking component in the detection consumables according to an embodiment of the present invention.

[0017] Explanation of reference numerals in the attached figures Detailed Implementation

[0018] The specific embodiments of this utility model will be described in detail below with reference to the accompanying drawings. It should be understood that the specific embodiments described herein are for illustration and explanation only and are not intended to limit the scope of this utility model.

[0019] The testing consumables of this utility model are described below with reference to the accompanying drawings.

[0020] like Figure 1 and Figure 2 As shown, this utility model provides a detection consumable, which includes a membrane breaking assembly 10, a detection assembly, and an adsorption filter element 40. The detection assembly includes a sample tube 20 and a reaction tube 30. The reaction tube 30 is located at the lower end of the sample tube 20 and is provided with a first sealing membrane 31. The sample tube 20 has a sample chamber 21 and a filter chamber 22 arranged sequentially from top to bottom. The filter chamber 22 has a liquid storage chamber 23 and a waste liquid chamber 24 arranged at intervals from top to bottom in the chamber wall. The cavity wall of the filter chamber 22 is provided with an outlet hole 221 and an inlet hole 222. The outlet hole 221 is connected to the storage cavity 23. The cavity wall of the filter chamber 22 is provided with a second sealing membrane (not shown in the figure) that seals the outlet hole 221. The inlet hole 222 is connected to the waste liquid cavity 24. The membrane breaking assembly 10 is movably disposed in the sample tube 20 and is used to sequentially break the second sealing membrane and puncture the first sealing membrane 31. The adsorption filter element 40 is disposed in the filter chamber 22 and is located between the outlet hole 221 and the inlet hole 222.

[0021] Specifically, the sample tube 20 has a sample chamber 21 and a filter chamber 22. The sample chamber 21 is used to hold the lysis buffer, and the filter chamber 22 is located below the sample chamber 21. A storage chamber 23 and a waste chamber 24 are formed within the wall of the filter chamber 22. The storage chamber 23 is used to store purification solutions such as washing solutions or eluents. The waste chamber 24 is spaced below the storage chamber 23. An outlet hole 221 is formed on the wall of the filter chamber 22 at a position corresponding to the storage chamber 23. The outlet hole 221 connects the storage chamber 23 and the filter chamber 22, and a second sealing membrane is affixed to the outlet hole 221 to seal the storage chamber. The liquid chamber 23 and the filter chamber 22 have inlet holes 222 on their walls corresponding to the positions of the waste liquid chamber 24. The inlet holes 222 are used to connect the waste liquid chamber 24 and the filter chamber 22. The filter chamber 22 is equipped with an adsorption filter element 40. The inlet holes 222 are spaced below the outlet holes 221. The adsorption filter element 40 is located between the outlet holes 221 and the inlet holes 222. In addition, the sample tube 20 is equipped with a membrane breaking component 10 that can move in the vertical direction. The lower end of the sample tube 20 is connected to a reaction tube 30. The opening of the reaction tube 30 is equipped with a first sealing membrane 31. The reaction tube 30 is used to hold the detection reagent.

[0022] When using the testing consumables, the sample is placed into the sample chamber 21 so that the lysis buffer can lyse the sample and form a sample solution. The sample solution flows downward from the sample chamber 21 into the filter chamber 22. When the sample solution flows through the adsorption filter 40, the adsorption filter 40 can adsorb the nucleic acid in the sample solution onto the adsorption filter 40. The unadsorbed waste liquid flows into the waste liquid chamber 24 through the inlet hole 222. Then, the membrane breaking component 10 moves downward and sequentially breaks the second sealing membrane and punctures the first sealing membrane 31, so that the purification treatment solution in the storage chamber 23 flows out from the outlet hole 221 and flows through the adsorption filter 40. The purification treatment solution mixes with the nucleic acid on the adsorption filter 40 to form a purified sample solution. The first sealing membrane 31 is broken to connect the filter chamber 22 and the reaction tube 30, so that the purified sample solution can flow from the filter chamber 22 into the reaction tube 30 to mix with the test reagent. This realizes the nucleic acid purification treatment of the sample, which greatly improves the nucleic acid purity, reduces impurities in the sample, and thus improves the accuracy of the test results.

[0023] Understandably, before the membrane breaking component 10 punctures the first sealing membrane 31, the first sealing membrane 31 seals the opening of the reaction tube 30, effectively preventing waste liquid from flowing into the reaction tube 30. The waste liquid can only flow into the waste liquid chamber 24 through the liquid inlet 222, thus achieving waste liquid collection. After the membrane breaking component 10 punctures the first sealing membrane 31, the first sealing membrane 31 breaks, making the filter chamber 22 and the reaction tube 30 connected. The purified sample solution flows directly into the reaction tube 30 under the action of gravity and mixes with the detection reagent, thus achieving nucleic acid purification.

[0024] It should be noted that the adsorption filter element 40 in this embodiment of the present invention can be made of silica gel. Nucleic acid can be adsorbed onto the silica gel adsorption filter element 40 under high salt concentration conditions. Waste liquid flows through the adsorption filter element 40 and is recovered into the waste liquid chamber 24 from the liquid inlet 222. Nucleic acid can be eluted from the adsorption filter element 40 under low salt concentration conditions. The purification solution flows through the adsorption filter element 40 and elutes the nucleic acid to form a purified sample solution, thereby realizing the separation and purification of nucleic acid.

[0025] In this embodiment of the present invention, the membrane breaking assembly 10 includes an injection push rod 11 and a piercing column 12. The injection push rod 11 is movably disposed in the sample chamber 21 and is provided with a membrane breaking blade 111. The piercing column 12 is disposed through the adsorption filter element 40. The injection push rod 11 is used to extend into the filter chamber 22 to make the membrane breaking blade 111 cut the second sealing membrane and push the piercing column 12 to pierce the first sealing membrane 31.

[0026] like Figure 2 , Figure 3 and Figure 5As shown, the injection pusher 11 can move vertically within the sample chamber 21, and is equipped with a membrane-breaking blade 111 for piercing the second sealing membrane. The upper end of the piercing column 12 passes through the adsorption filter element 40, and the lower end of the piercing column 12 is used to pierce the first sealing membrane 31. When the adsorption filter element 40 adsorbs nucleic acid and waste liquid flows into the waste liquid chamber 24, the injection pusher 11 moves downward and extends into the filtration chamber 22, so that the membrane-breaking blade 111 pierces the second sealing membrane, and the purified treatment liquid in the storage chamber 23 can flow out from the outlet hole 221 to the filter. Inside the cavity 22, nucleic acid is eluted as it flows through the adsorption filter 40. The injection pusher 11 moves downward and comes into contact with the piercing column 12, allowing the injection pusher 11 to push the lower end of the piercing column 12 to pierce the first sealing membrane 31. The purified sample solution formed by mixing the purified treatment solution and nucleic acid can flow into the reaction tube 30 to mix with the detection reagent. This shortens the travel distance of the injection pusher 11, and by pushing the piercing column 12 to pierce the first sealing membrane 31, the filter cavity 22 and the reaction tube 30 can be quickly connected, effectively preventing the purified sample solution from flowing into the waste liquid cavity 24. The structure is ingeniously designed.

[0027] In this embodiment of the invention, a third sealing membrane 25 is provided inside the sample tube 20. The third sealing membrane 25 is located between the sample chamber 21 and the filter chamber 22. The lower end of the injection push rod 11 is provided with a piercing tip 112 for piercing the third sealing membrane 25. Figure 2 , Figure 4 and Figure 5 As shown, the third sealing membrane 25 is located at the upper end of the filter chamber 22 and is used to seal the filter chamber 22, effectively preventing external impurities from entering the filter chamber 22 during the process of adding the sample into the sample chamber 21. This further reduces the introduction of impurities and improves the accuracy of the detection results. In addition, the lower end of the injection push rod 11 is provided with a piercing tip 112. After the sample and lysis buffer are mixed to form a sample solution, the injection push rod 11 moves downward so that the piercing tip 112 pierces the third sealing membrane 25. The third sealing membrane 25 ruptures to connect the sample chamber 21 and the filter chamber 22, allowing the sample solution to flow. The sample solution enters the filter chamber 22 and flows through the adsorption filter element 40, which adsorbs nucleic acids from the sample solution. The waste liquid flows into the waste liquid chamber 24. Then, the injection pusher 11 moves downward so that the membrane rupture blade 111 ruptures the second sealing membrane. The purification solution washes away the nucleic acid to achieve nucleic acid purification. Then, the injection pusher 11 moves downward to push the piercing column 12 to pierce the first sealing membrane 31. The purified sample solution flows into the reaction tube 30 and mixes with the detection reagent, effectively reducing impurities in the sample, improving nucleic acid purity, and thus improving the accuracy of the detection results.

[0028] In this embodiment of the present invention, the injection push rod 11 includes a push rod section 113 and a piston rod section 114. The piston rod section 114 is movably disposed in the sample chamber 21. The lower end of the piston rod section 114 is provided with a membrane-breaking blade 111 and a piercing tip 112. A partition guide plate 1141 is provided on the piston rod section 1141, and a placement opening 1142 is provided on the partition guide plate 1141. The push rod section 113 is movably disposed above the piston rod section 114 and passes through the sample tube 20. The push rod section 113 is used to push the piston rod section 114 into the filter chamber 22.

[0029] like Figure 2 , Figure 3 and Figure 5 As shown, the piston rod section 114 is movably disposed within the sample chamber 21. The piston rod section 114 is equipped with a rupture blade 111 for piercing the second sealing membrane and a piercing tip 112 for piercing the third sealing membrane 25. The piston rod section 114 is used to abut against the piercing column 12 to push the piercing column 12 to pierce the first sealing membrane 31. The push rod section 113 is movably disposed through the sample tube 20 and is used to push the piston rod section 114 downwards. This allows the piston rod section 114 to be removed from the sample chamber 21 when a sample is placed into the sample chamber 21; only the push rod section 113 needs to be removed to place the sample, effectively preventing impurities from adhering to the piston rod section 114. This reduces the introduction of impurities and improves sample purity. Furthermore, the piston rod section 114 is provided with a partition guide plate 1141, which can partially block the sample cavity 21 to further reduce the introduction of impurities. The size of the partition guide plate 1141 is adapted to the size of the sample cavity 21 to guide the movement of the piston rod section 114, preventing the piston rod section 114 from tilting or shaking. In addition, the partition guide plate 1141 is provided with a placement port 1142, which is used to place the sampling swab carrying the sample into the sample cavity 21, so that the sample on the sampling swab can be mixed with the lysis solution to form a sample solution, improving the convenience and flexibility of sampling.

[0030] Furthermore, such as Figures 1 to 4 As shown, the sample tube 20 includes a tube body 28 and a sealing cap 29. The tube body 28 has a sample cavity 21 and a filter cavity 22. The reaction tube 30 is located at the lower end of the tube body 28. The sealing cap 29 is threaded to the upper end of the tube body 28. The push rod section 113 passes through the sealing cap 29. When placing a sample into the sample cavity 21, the sealing cap 29 is unscrewed to remove the sealing cap 29 and the push rod section 113, and the sample can be placed into the sample cavity 21, which further improves the convenience of sampling.

[0031] In this embodiment of the present invention, a guide seat 26 is provided in the sample cavity 21, and the guide seat 26 is spaced below the partition guide plate 1141. A guide channel 261 for the piston rod section 114 to pass through is provided on the guide seat 26, and the size of the guide channel 261 gradually decreases from top to bottom.

[0032] like Figures 2 to 4 As shown, the guide seat 26 is located at the lower end of the sample cavity 21. A guide channel 261 is provided on the guide seat 26. The size of the guide channel 261 gradually decreases from top to bottom. The piston rod section 114 passes through the guide channel 261. The guide channel 261 guides the movement of the piston rod section 114, further preventing the piston rod section 114 from deviating or shaking, and improving the smoothness of the movement of the piston rod section 114.

[0033] In this embodiment of the invention, the upper end of the piercing post 12 is provided with a mating groove 121, which is used for the piercing tip 112 to extend into. Figures 2 to 5 As shown, the push rod section 113 pushes the piston rod section 114 downward, and the piston rod section 114 sequentially drives the piercing tip 112 to pierce the third sealing membrane 25, and the membrane-breaking blade 111 to cut the second sealing membrane. Then, the piercing tip 112 of the piston rod section 114 moves downward and extends into the docking groove 121, so that the piston rod section 114 can push the piercing column 12 to pierce the first sealing membrane 31, so that the purified sample liquid flows into the reaction tube 30. The docking groove 121 serves to guide the piercing tip 112 to extend into the reaction tube 30, making it easier for the piston rod section 114 to push the piercing column 12, effectively preventing the piston rod section 114 from deflecting or shaking, and improving the piercing reliability of the first sealing membrane 31.

[0034] In this embodiment of the present invention, there are two liquid outlet holes 221, which are spaced apart from top to bottom on the wall of the filter chamber 22. The number of liquid storage chambers 23 is the same as the number of liquid outlet holes 221 and they are connected in a one-to-one correspondence. There are two second sealing membranes, which seal the two liquid outlet holes 221 respectively. The membrane breaking component 10 is used to break the two second sealing membranes from top to bottom in sequence.

[0035] like Figure 2 and Figure 4As shown, two outlet holes 221 are spaced apart on the wall of the filter chamber 22 in the vertical direction. A storage chamber 23 is provided in the wall of the filter chamber 22 corresponding to each outlet hole 221. The two storage chambers 23 can be used to store washing solution and elution solution respectively. A second sealing membrane is attached to each of the two outlet holes 221. A membrane-breaking blade 111 is provided on the piston rod section 114 corresponding to each second sealing membrane. When the piston rod section 114 moves downward, each membrane-breaking blade 111 can break the corresponding second sealing membrane, so that the washing solution and elution solution flow out in sequence and are used for nucleic acid washing and elution purification, respectively, which further improves the purity of nucleic acid and improves the accuracy of detection results.

[0036] In a preferred embodiment of this utility model, such as Figure 2 and Figure 4 As shown, the two outlet holes 221 are respectively designated as washing outlet hole 221a and elution outlet hole 221b. Washing outlet hole 221a is spaced above elution outlet hole 221b, and the washing outlet hole 221a and elution outlet hole 221b are arranged circumferentially around the filter chamber 22. The storage chamber 23 inside the filter chamber 22, which communicates with washing outlet hole 221a, is called washing storage chamber 23a. Washing storage chamber 23a is used to store washing liquid, and the storage chamber 23a is used to store the washing liquid inside the filter chamber 22. The storage chamber 23 connected to the elution outlet 221b is the elution storage chamber 23b, which is used to store the eluent. The washing storage chamber 23a and the elution storage chamber 23b are arranged circumferentially. A second sealing membrane is attached to the washing outlet 221a and the elution outlet 221b respectively. The lower end of the piston rod section 114 is provided with two membrane-breaking blades 111 arranged in opposite directions. The two membrane-breaking blades 111 are used to cut the two second sealing membranes respectively.

[0037] When using the testing consumables, first unscrew the sealing cap 29 to remove the sealing cap 29 and the push rod section 113. Place the sample into the sample chamber 21 through the placement port 1142, allowing the sample to mix with the lysis buffer to form a sample solution. The push rod section 113 pushes the piston rod section 114 downwards, causing the piercing tip 112 to pierce the third sealing membrane 25. The sample solution flows into the filter chamber 22, where the adsorption filter 40 adsorbs the nucleic acid in the sample solution. The waste liquid flows into the waste liquid chamber 24. The piston rod section 114 moves downwards, causing one of the membrane-breaking blades 111 to puncture the second sealing membrane at the washing outlet 221a. The washing solution flows out from the washing reservoir 23a to clean the adsorption filter. The nucleic acid adsorbed on the filter element 40 is washed and purified. Then, the piston rod 114 moves downward so that another membrane-breaking blade 111 breaks the second sealing membrane at the elution outlet 221b. The elution solution flows out from the elution reservoir 23b to elute the nucleic acid on the adsorption filter element 40. The piercing tip 112 of the piston rod 114 extends into the docking groove 121 to push the piercing column 12 to pierce the first sealing membrane 31. The purified sample solution formed by the mixture of elution solution and nucleic acid can flow into the reaction tube 30 to mix with the detection reagent. This process realizes the washing and elution of nucleic acid purification of the sample, which greatly improves the purity of nucleic acid and thus improves the accuracy of the detection results.

[0038] In this embodiment of the invention, the waste liquid chamber 24 is provided with absorbent foam 241. For example... Figures 2 to 4 As shown, the waste liquid chamber 24 is filled with absorbent foam 241 for absorbing waste liquid. The absorbent foam 241 has strong water absorption, so that it can absorb the waste liquid at the inlet hole 222 into the waste liquid chamber 24, effectively preventing waste liquid from remaining in the filter chamber 22, and further improving the purity of nucleic acid. In addition, there are multiple inlet holes 222, which are arranged at intervals on the wall of the filter chamber 22, so that the absorbent foam 241 can absorb waste liquid from multiple inlet holes 222, improving the reliability and efficiency of waste liquid recovery.

[0039] In this embodiment of the invention, a mounting groove 27 is provided at the lower end of the sample tube 20. The mounting groove 27 communicates with the filter chamber 22, and the reaction tube 30 extends into and is installed in the mounting groove 27. Figure 1 , Figure 2 and Figure 4 As shown, the lower end of the tube body 28 is provided with an installation groove 27 for the reaction tube 30 to extend into. The reaction tube 30 is provided with a snap-fit ​​protrusion that can be snapped into the installation groove 27 to increase the connection strength with the tube body 28, ensuring a stable and reliable connection and effectively preventing the reaction tube 30 from loosening. Furthermore, the upper end of the reaction tube 30 extends into the installation groove 27, further preventing external impurities from entering the filter chamber 22 or the reaction tube 30, thus improving the structural sealing performance.

[0040] In addition, this utility model also provides a sample testing device, which includes the testing consumables described above, and the specific structure of the testing consumables is as described in the above embodiments. Since the sample testing device adopts all the technical solutions of the above embodiments, it has at least all the beneficial effects brought about by the technical solutions of the above embodiments, which will not be described in detail here.

[0041] In the description of this utility model, it should be understood that the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Therefore, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this utility model, "multiple" means at least two, such as two, three, etc., unless otherwise explicitly specified.

[0042] In this utility model, unless otherwise explicitly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection, an electrical connection, or a connection that allows communication between them; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise explicitly limited. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0043] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. Moreover, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of different embodiments or examples.

[0044] Although embodiments of the present invention have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention. Those skilled in the art can make changes, modifications, substitutions and variations to the above embodiments within the scope of the present invention.

Claims

1. A testing consumable, characterized in that, The testing consumables include: Membrane breaking assembly (10); The detection assembly includes a sample tube (20) and a reaction tube (30). The reaction tube (30) is located at the lower end of the sample tube (20), and a first sealing membrane (31) is provided on the reaction tube (30). The sample tube (20) has a sample chamber (21) and a filter chamber (22) arranged sequentially from top to bottom. The filter chamber (22) has a liquid storage chamber (23) and a waste liquid chamber (24) arranged at intervals from top to bottom in the chamber wall. The chamber wall of the filter chamber (22) The sample tube (20) is provided with an outlet hole (221) and an inlet hole (222). The outlet hole (221) is connected to the storage chamber (23). The filter chamber (22) is provided with a second sealing membrane on its wall to seal the outlet hole (221). The inlet hole (222) is connected to the waste liquid chamber (24). The membrane breaking assembly (10) is movably disposed in the sample tube (20) and is used to sequentially break the second sealing membrane and puncture the first sealing membrane (31). An adsorption filter element (40) is disposed in the filter chamber (22) and located between the liquid outlet (221) and the liquid inlet (222).

2. The testing consumables according to claim 1, characterized in that, The membrane breaking assembly (10) includes an injection push rod (11) and a piercing column (12). The injection push rod (11) is movably disposed in the sample chamber (21) and is provided with a membrane breaking blade (111). The piercing column (12) passes through the adsorption filter element (40). The injection push rod (11) is used to extend into the filter chamber (22) to make the membrane breaking blade (111) break the second sealing membrane and push the piercing column (12) to pierce the first sealing membrane (31).

3. The testing consumables according to claim 2, characterized in that, The sample tube (20) is provided with a third sealing membrane (25), which is located between the sample chamber (21) and the filter chamber (22). The lower end of the injection push rod (11) is provided with a piercing tip (112) for piercing the third sealing membrane (25).

4. The testing consumables according to claim 3, characterized in that, The injection push rod (11) includes a push rod section (113) and a piston rod section (114). The piston rod section (114) is movably disposed in the sample chamber (21). The lower end of the piston rod section (114) is provided with the membrane-breaking blade (111) and the puncture tip (112). The piston rod section (114) is provided with a partition guide plate (1141). The partition guide plate (1141) has a placement opening (1142). The push rod section (113) is movably disposed above the piston rod section (114) and passes through the sample tube (20). The push rod section (113) is used to push the piston rod section (114) into the filter chamber (22).

5. The testing consumables according to claim 4, characterized in that, The sample cavity (21) is provided with a guide seat (26), and the guide seat (26) is spaced below the partition guide plate (1141). The guide seat (26) is provided with a guide channel (261) for the piston rod section (114) to pass through, and the size of the guide channel (261) gradually decreases from top to bottom.

6. The testing consumables according to claim 3, characterized in that, The upper end of the piercing post (12) is provided with a docking groove (121), which is used for the piercing tip (112) to extend into.

7. The testing consumables according to any one of claims 1 to 6, characterized in that, The number of liquid outlet holes (221) is set to two, and the two liquid outlet holes (221) are opened at intervals from top to bottom on the cavity wall of the filter cavity (22). The number of liquid storage cavities (23) is the same as the number of liquid outlet holes (221) and they are connected one by one. The number of second sealing membranes is set to two, and the two second sealing membranes seal the two liquid outlet holes (221) one by one. The membrane breaking assembly (10) is used to break the two second sealing membranes from top to bottom in sequence.

8. The testing consumables according to any one of claims 1 to 6, characterized in that, The waste liquid chamber (24) is equipped with absorbent foam (241).

9. The testing consumables according to any one of claims 1 to 6, characterized in that, The sample tube (20) has an installation groove (27) at its lower end. The installation groove (27) is connected to the filter chamber (22). The reaction tube (30) extends into and is installed in the installation groove (27).

10. A sample testing device, characterized in that, The sample testing equipment includes testing consumables according to any one of claims 1 to 9.

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