Liquid container for tissue dissociation
Patent Information
- Application Number
- CN202521810953.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-08-25
- Publication Date
- 2026-10-30
- Estimated Expiration
- 2035-08-25
AI Technical Summary
[0003]这种设计虽有效保障了运行稳定性,却显著增加了刀头更换作业的复杂性、操作强度和时间成本,导致更换效率低下,成为影响实验通量和操作便捷性的关键瓶颈
[0014]1.本实用新型中,换刀时,先拔下筒盖整体,再下压支撑架,此时,两个弹簧受力收缩,为U形压杆提供下降空间,使刀具能够从密封旋盖与支撑架之间脱落,之后即可取出适配的刀具进行安装,该结构简单,安装方便。
Smart Images

Figure CN224917789U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of liquid container technology, specifically a liquid container for tissue dissociation. Background Technology
[0002] In traditional tissue dissociation barrel applications, the dissociation cutter assembly (e.g., blade type, geometry) needs to be frequently replaced to accommodate different physical properties of cellular tissues (e.g., hardness, toughness). To ensure the high-speed stability of the drive unit and the coaxial accuracy of the cutter head movement during dissociation, the connection between the cutter head and the drive shaft generally employs a highly robust mechanical structure (e.g., precision thread locking, strong snap-fit, or pin fixing).
[0003] While this design effectively ensures operational stability, it significantly increases the complexity, intensity, and time cost of tool replacement, resulting in low replacement efficiency and becoming a key bottleneck affecting experimental throughput and ease of operation. Utility Model Content
[0004] This utility model aims to solve one of the technical problems existing in the prior art or related technologies.
[0005] Therefore, the technical solution adopted by this utility model is as follows:
[0006] A liquid container for tissue dissociation includes a container mechanism and a blade changing mechanism. The container mechanism includes a shell and a cap that is interference-fitted to the shell. The blade changing mechanism includes a sealing cap located inside the shell and screwed to the cap, a U-shaped pressure rod slidably penetrating the bottom of the sealing cap, two springs located inside the sealing cap and sleeved on the top of the U-shaped pressure rod, a blade slidably penetrating the bottom of the sealing cap and rotatably inserted with the U-shaped pressure rod, and a support frame fixedly connected to the top of the cap.
[0007] By adopting the above technical solution, when changing the tool, first remove the entire cylinder cover, then press down the support frame. At this time, the two springs are compressed, providing space for the U-shaped pressure rod to descend, allowing the tool to fall off between the sealing cap and the support frame. Then, the appropriate tool can be taken out for installation. This structure is simple and easy to install.
[0008] In a preferred embodiment, the present invention can be further configured such that: the cylinder cover is provided with a transmission assembly, the transmission assembly including a rod sleeve that rotates through the top of the cylinder cover, a transmission rod that vertically penetrates through the rod sleeve, and a protrusion integrally formed on the outer wall of the cutter, wherein the cutter and the protrusion both slide to extend into the interior of the transmission rod.
[0009] In a preferred embodiment, the present invention can be further configured such that: the sealing cap is configured as an inverted "T" shape, the outer edge of the sealing cap is press-fitted with the inner wall of the cylinder shell, and the sealing cap is made of rubber material.
[0010] In a preferred embodiment, the present invention can be further configured such that the U-shaped pressure bar is suspended at the bottom of the inner cavity of the cylinder shell, and both the U-shaped pressure bar and the cutting tool are made of hydrophobic material.
[0011] In a preferred embodiment, the present invention can be further configured such that the top of the support frame is frame-shaped, and the transmission rod rotates through the top of the support frame.
[0012] In a preferred embodiment, the present invention can be further configured such that: a plurality of ball bearing seats are fixedly connected to the top of the support frame, the plurality of ball bearing seats are arranged in a matrix, and the top of the ball bearing seats and the top of the transmission rod are located on the same horizontal plane.
[0013] By adopting the above technical solution, the beneficial effects achieved by this utility model are as follows:
[0014] 1. In this utility model, when changing the tool, first remove the entire cylinder cover, then press down the support frame. At this time, the two springs are compressed by force, providing space for the U-shaped pressure rod to descend, so that the tool can fall off between the sealing cap and the support frame. Then the appropriate tool can be taken out for installation. This structure is simple and easy to install.
[0015] 2. In this utility model, the cylinder cap is installed upside down in the external tissue dissociation instrument, so that the internal drive structure is connected to the transmission rod, which can drive the blade to rotate, thus creating conditions for rapid collection of tissue fluid. Attached Figure Description
[0016] Figure 1 This is a perspective view of the overall structure of this utility model;
[0017] Figure 2 This is a schematic diagram of the container mechanism of this utility model;
[0018] Figure 3 This is a schematic diagram of the tool changing mechanism assembly of this utility model;
[0019] Figure 4 This is an exploded view of the overall structure of this utility model;
[0020] Figure 5 This utility model Figure 4 Enlarged view of the structure of part A.
[0021] Figure label:
[0022] 100. Container mechanism; 110. Shell; 120. Lid;
[0023] 200. Tool changing mechanism; 210. Sealing cap; 220. U-shaped pressure bar; 230. Spring; 240. Tool; 250. Support frame;
[0024] 300. Transmission assembly; 310. Rod sleeve; 320. Transmission rod; 330. Protrusion;
[0025] 400. Ball bearing seat. Detailed Implementation
[0026] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to specific embodiments and accompanying drawings. It should be noted that, unless otherwise specified, the embodiments and features of the present utility model can be combined with each other.
[0027] It should be understood that these descriptions are merely exemplary and not intended to limit the scope of this invention.
[0028] The following describes, with reference to the accompanying drawings, some embodiments of the present invention, providing a liquid container for tissue dissociation.
[0029] Example 1:
[0030] Combination Figures 1-5 As shown, the present invention provides a liquid container for tissue dissociation, including a container mechanism 100 and a blade changing mechanism 200. The container mechanism 100 includes a cylinder shell 110 and a cylinder cover 120 that is interference-fitted to the cylinder shell 110.
[0031] The tool changing mechanism 200 includes a sealing cap 210 located inside the cylindrical shell 110 and screwed to the cylindrical cover 120, a U-shaped pressure rod 220 slidably passing through the bottom of the sealing cap 210, two springs 230 located inside the sealing cap 210 and sleeved on the top of the U-shaped pressure rod 220, a tool 240 slidably passing through the bottom of the sealing cap 210 and rotatably inserted into the U-shaped pressure rod 220, and a support frame 250 fixedly connected to the top of the U-shaped pressure rod 220. The support frame 250 slidably passes through the top of the cylindrical cover 120.
[0032] Furthermore, the sealing cap 210 is configured as an inverted "T" shape, the outer edge of the sealing cap 210 is press-fitted with the inner wall of the cylinder shell 110, and the sealing cap 210 is made of rubber material. The shape, size and material design of the sealing cap 210 effectively improve the sealing performance of the cylinder cap 120 to the cylinder shell 110.
[0033] Furthermore, the U-shaped pressure rod 220 is suspended at the bottom of the inner cavity of the cylindrical shell 110. Both the U-shaped pressure rod 220 and the cutter 240 are made of hydrophobic material. Using hydrophobic material can prevent tissue fluid from adhering to the surface of the U-shaped pressure rod 220 and the cutter 240, thereby reducing the loss of tissue fluid during the cutter change process.
[0034] Furthermore, the top of the support frame 250 is frame-shaped, and the transmission rod 320 rotates through the top of the support frame 250. The shape design of the support frame 250 can increase the contact area between the cover 120 and the external tissue dissociation instrument when the cover 120 is inserted upside down, making the rotation of the shell 110 more stable.
[0035] Example 2:
[0036] Combination Figure 1 , 3 4 and Figure 5 As shown, based on Embodiment 1, the cylinder cover 120 is provided with a transmission assembly 300. The transmission assembly 300 includes a rod sleeve 310 that rotatably passes through the top of the cylinder cover 120, a transmission rod 320 that vertically passes through the rod sleeve 310, and a protrusion 330 integrally formed on the outer wall of the cutter 240. The cutter 240 and the protrusion 330 both slide to the inside of the transmission rod 320. Through the transmission assembly 300, the cutter 240 can be quickly connected to the drive structure of the external tissue dissociation instrument.
[0037] Example 3:
[0038] Combination Figure 1 , 2 4 and Figure 5 As shown in the above embodiment, a plurality of ball bearing seats 400 are fixedly connected to the top of the support frame 250. The plurality of ball bearing seats 400 are arranged in a matrix. The top of the ball bearing seats 400 and the top of the transmission rod 320 are located on the same horizontal plane. The ball bearing seats 400 are provided so that the support frame 250 rotates more smoothly when it is close to the external tissue dissociation instrument.
[0039] The working principle and usage process of this utility model are as follows: In the initial state, the blade 240 penetrates the bottom of the sealing cap 210, with its bottom end inserted into the U-shaped pressure rod 220 and its top end inserted into the bottom end of the transmission rod 320. At this time, the U-shaped pressure rod 220, under the elastic force of the two springs 230, effectively stabilizes the blade 240 and prevents its top end from separating from the bottom end of the transmission rod 320. Subsequently, the cylinder cap 120 is installed upside down in the external tissue dissociation instrument, so that the internal drive structure is inserted into the transmission rod 320, which can drive the blade 240 to rotate, creating conditions for rapid collection of tissue fluid. When changing blades, first remove the cylinder cap 120 as a whole, and then press down the support frame 250. At this time, the two springs 230 are compressed by force, providing space for the U-shaped pressure rod 220 to descend, allowing the blade 240 to fall out from between the sealing cap 210 and the support frame 250. After that, the appropriate blade 240 can be taken out for installation. This structure is simple and easy to install.
[0040] Although embodiments of the present invention have been shown and described, those skilled in the art will understand that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the claims and their equivalents.
Claims
1. A liquid container for tissue dissociation, characterized in that, include: A container mechanism (100) includes a cylindrical shell (110) and a cylindrical cover (120) that is interference-fitted to the cylindrical shell (110); The tool changing mechanism (200) includes a sealing cap (210) located inside the cylinder shell (110) and screwed to the cylinder cover (120), a U-shaped pressure rod (220) slidably passing through the bottom of the sealing cap (210), two springs (230) located inside the sealing cap (210) and sleeved on the top of the U-shaped pressure rod (220), a tool (240) slidably passing through the bottom of the sealing cap (210) and rotatably inserted with the U-shaped pressure rod (220), and a support frame (250) fixedly connected to the top of the U-shaped pressure rod (220). The support frame (250) slidably passes through the top of the cylinder cover (120).
2. The liquid container for tissue dissociation according to claim 1, characterized in that, The cylinder cover (120) is provided with a transmission assembly (300), which includes a rod sleeve (310) that rotatably passes through the top of the cylinder cover (120), a transmission rod (320) that vertically passes through the rod sleeve (310), and a protrusion (330) integrally formed on the outer wall of the cutter (240). The cutter (240) and the protrusion (330) both slide to the inside of the transmission rod (320).
3. The liquid container for tissue dissociation according to claim 1, characterized in that, The sealing cap (210) is configured as an inverted "T" shape, and the outer edge of the sealing cap (210) is press-fitted with the inner wall of the cylinder shell (110). The sealing cap (210) is made of rubber material.
4. The liquid container for tissue dissociation according to claim 1, characterized in that, The U-shaped pressure bar (220) is suspended at the bottom of the inner cavity of the cylindrical shell (110), and both the U-shaped pressure bar (220) and the cutter (240) are made of hydrophobic material.
5. A liquid container for tissue dissociation according to claim 2, characterized in that, The top of the support frame (250) is frame-shaped, and the transmission rod (320) rotates through the top of the support frame (250).
6. A liquid container for tissue dissociation according to claim 2, characterized in that, The support frame (250) has multiple ball bearing seats (400) fixedly connected to its top. The multiple ball bearing seats (400) are arranged in a matrix. The top of the ball bearing seats (400) and the top of the transmission rod (320) are located on the same horizontal plane.
