A paraffin-embedded tissue block slicing device

Abstract

The utility model discloses a paraffin embedding tissue block section device, including the organism, is provided with the wax block placing seat that can reciprocate up and down at the front surface, the material collection base is installed the bottom end front surface position of machine body, cutting part is installed in the material collection base, and the whole is below the wax block placing seat, the inside of material collection base is provided with collection subassembly, and this collection subassembly includes collection part and cleaning part, wherein: the collection part is embedded in the inside of material collection base, and the cleaning part is slidably arranged in the inside of collection part, through the design of the utility model, the independent detachable material collection bin is added in the traditional collection base, and the unified collection is made to the waste material, when needing to clean, the operator only takes out the whole material collection bin from the material collection base and cleans, not only avoids the cross -contamination risk that the cutting scrap flies of traditional brush scraping sweeps simultaneously does not need to make any dismounting to the material collection base.

Description

Technical Field

[0001] This utility model belongs to the technical field of slicing devices, specifically relating to a slicing device for paraffin-embedded tissue blocks. Background Technology

[0002] Innovative drug development requires in-depth research into the mechanisms of action of drugs on target organs and tissues. Therefore, it necessitates the use of slicing devices to cut paraffin-embedded tissue blocks into thin sections, providing a foundation for subsequent observation. For example, in anticancer drug research, tumor tissue treated with the drug is embedded in paraffin. After slicing, staining can be used to observe cell apoptosis and morphological changes. Nucleic acids can also be extracted to analyze gene expression changes, clarifying the drug's targets and effects. This provides intuitive and precise data support for the safety and efficacy evaluation and optimization of innovative drugs, thus accelerating the new drug development process.

[0003] In the paraffin-embedded tissue sectioning process, which is widely used in current innovative drug research and development and pathological analysis, the paraffin debris generated during the operation of existing sectioning devices can be initially collected by the collection base. However, due to the adhesion characteristics of the debris to the inner wall of the base, operators need to manually scrape it with auxiliary tools such as brushes. This process requires repeated disassembly of the base components, increasing the risk of equipment damage, and therefore has significant limitations. Utility Model Content

[0004] The purpose of this invention is to provide a paraffin-embedded tissue block slicing device to solve the problem of difficult waste removal in existing slicing devices mentioned in the background art.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a paraffin-embedded tissue block slicing device, comprising...

[0006] The body has a wax block holder that can move up and down back and forth on the front surface;

[0007] A material collection base is installed on the bottom front surface of the machine body;

[0008] The cutting component is installed inside the aggregate base and is positioned entirely below the wax block placement seat;

[0009] The material collection base is internally equipped with a collection component, which includes a collection part and a cleaning part, wherein:

[0010] The collecting component is embedded inside the material collection base, while the cleaning component is slidably disposed inside the collecting component.

[0011] Preferably, the collecting component includes a collection bin, the outer wall of which is fully fitted with the inner wall of the collection base, and handles are provided on both sides of the collection bin, which can be quickly and easily pulled out from the inside of the collection base.

[0012] Preferably, the bottom surface of the collection bin has a placement groove, and a bottom plate is provided inside the placement groove. The end of the handle extends through the placement groove and is fixedly connected to the bottom plate. The thickness of the bottom plate is equal to the inner depth of the placement groove. When it is necessary to clean the chips collected inside the collection bin, first pull the handle upward, and then pull the collection bin out from the collection base. Then, stop holding one of the handles, and the handle at that point will descend under gravity, causing the bottom plate to separate from the placement groove. Then, hold the bottom plate and flip the entire collection bin over to realize the dumping of the collection bin. Alternatively, the collection bin can be shaken back and forth by the bottom plate to achieve efficient material discharge.

[0013] Preferably, the front and rear surfaces inside the collection bin are both fixed with slide rails, and a scraper is slidably arranged on the inner side of the slide rails. During slicing, the main chips are concentrated in the middle position of the collection bin. When the chips in the middle position are high, the chips can be guided to the sides by moving the scraper back and forth. The scraper has an opening at its end, and the inner wall of the opening is recessed outward. The upper and lower end faces of the slide rail are formed with grooves to fit the recess, thereby realizing the sliding connection between the scraper and the slide rail.

[0014] Preferably, it also includes a knife holder, and the inside of the material collection base is formed with an integral placement platform, and one end of the material collection bin has a concave portion that partially wraps around the placement platform; the knife holder is installed at the top of the placement platform.

[0015] Preferably, the cutting component includes a blade holder positioned directly below the wax block holder. A blade is mounted on top of the blade holder, positioned in front of the wax block holder. During slicing, paraffin wax is placed on the wax block holder, and then a handwheel is rotated to move the wax block holder up and down, causing the paraffin wax to contact the blade and be cut into slices. This working principle is existing technology and will not be described further here.

[0016] Preferably, a handwheel is also installed on the outside of the machine body. The handwheel is connected to the wax block placement seat for transmission. The reciprocating lifting and lowering of the wax block placement seat is realized by rotating the handwheel. The working principle and structure of this part are existing technologies, so they will not be described in detail here.

[0017] Compared with the prior art, the beneficial effects of this utility model are:

[0018] By adding an independent and detachable collection bin to the traditional collection base, waste materials can be collected in a unified manner. When cleaning is required, the operator only needs to remove the entire collection bin from the collection base for cleaning. This not only avoids the risk of flying chips and cross-contamination caused by traditional brush scraping, but also eliminates the need to disassemble the collection base. This improves the shortcomings of the existing device in cleaning. Attached Figure Description

[0019] Figure 1 This is a schematic diagram of the structure of this utility model;

[0020] Figure 2 This is a schematic diagram showing the connection between the material collection base and the material collection bin of this utility model;

[0021] Figure 3 This is a schematic diagram of the state of the present invention when preparing to tilt the collection bin to unload materials;

[0022] Figure 4 This utility model Figure 3 A structural diagram viewed from below;

[0023] Figure 5 This is an enlarged schematic diagram of the connection between the scraper and the slide rail of this utility model.

[0024] In the picture:

[0025] 100. Machine body; 101. Wax block holder; 102. Handwheel; 103. Material collection base; 104. Placement platform;

[0026] 200. Tool holder; 201. Blade;

[0027] 300. Collection bin; 301. Handle; 302. Scraper; 303. Slide rail; 304. Base plate; 305. Placement trough. Detailed Implementation

[0028] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0029] Please see Figures 1 to 4 This utility model provides a technical solution: a paraffin-embedded tissue block sectioning device, comprising...

[0030] The body 100 has a wax block holder 101 that can move up and down reciprocally on its front surface;

[0031] The material collection base 103 is installed on the bottom front surface of the machine body 100;

[0032] The cutting component is installed inside the material collection base 103 and is located entirely below the wax block placement seat 101;

[0033] The material collection base 103 is internally equipped with a collection component, which includes a collection part and a cleaning part, wherein:

[0034] The collecting component is embedded inside the collecting base 103, while the cleaning component is slidably disposed inside the collecting component.

[0035] In this embodiment, preferably, the collecting component includes a collection bin 300, the outer wall of which is fully fitted with the inner wall of the collection base 103, and handles 301 are provided on both sides of the collection bin 300, which can be quickly and conveniently pulled out from the inside of the collection base 103.

[0036] In this embodiment, preferably, the bottom end face of the collection bin 300 is provided with a placement groove 305. The placement groove 305 is provided with a bottom plate 304. The end of the handle 301 extends into the placement groove 305 and is fixedly connected to the bottom plate 304. The thickness of the bottom plate 304 is equal to the inner depth of the placement groove 305. When it is necessary to clean the chips collected inside the collection bin 300, first pull the handle 301 upward, and then pull the collection bin 300 out from the collection base 103. Then, stop holding one of the handles 301. The handle 301 at this point descends under gravity, causing the bottom plate 304 to separate from the placement groove 305. Then, hold the bottom plate 304 and flip the entire collection bin 300 to realize the dumping of the collection bin 300. Alternatively, the collection bin 300 can be shaken back and forth by the bottom plate 304 to achieve efficient material discharge.

[0037] In this embodiment, preferably, slide rails 303 are fixedly provided on both the front and rear surfaces inside the collection bin 300, and scraper 302 is slidably provided on the inner side of the slide rail 303. In the cutting process, the main chips are concentrated in the middle position of the collection bin 300. When the chips in the middle position are high, the chips can be guided to the two sides by moving the scraper 302 back and forth. The end of the scraper 302 has an opening, and the inner wall of the opening is recessed outward. The upper and lower end faces of the slide rail 303 are formed with grooves to fit the recess, thereby realizing the sliding connection between the scraper 302 and the slide rail 303.

[0038] In this embodiment, preferably, it also includes a knife holder 200, and an integral placement platform 104 is formed inside the material collection base 103. One end of the material collection bin 300 has a concave portion that partially wraps around the placement platform 104. The knife holder 200 is installed at the top of the placement platform 104.

[0039] In this embodiment, preferably, the cutting component includes a blade holder 200, which is positioned directly below the wax block holder 101. A blade 201 is also mounted on the top of the blade holder 200, positioned in front of the wax block holder 101. During slicing, paraffin wax is placed on the wax block holder 101, and then the handwheel 102 is rotated. The handwheel 102 drives the wax block holder 101 to move up and down, causing the paraffin wax to contact the blade 201 and be cut into slices by the blade 201. This working principle is existing technology and will not be described further here.

[0040] In this embodiment, preferably, a handwheel 102 is also installed on the outside of the body 100. The handwheel 102 is connected to the wax block placement seat 101. The wax block placement seat 101 is reciprocated and raised by rotating the handwheel 102. The working principle and structure of this part are existing technologies, so they will not be described in detail here.

[0041] Although embodiments of the present invention have been shown and described (see the detailed description above), it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A device for sectioning paraffin-embedded tissue blocks, comprising: The body (100) has a wax block holder (101) that can move up and down reciprocally on the front surface. The material collection base (103) is installed on the bottom front surface of the machine body (100); The cutting component is installed inside the aggregate base (103) and is located entirely below the wax block placement seat (101); Its features are: The material collection base (103) is internally provided with a collection component, which includes a collection element and a cleaning element, wherein: The collecting component is embedded inside the collecting base (103), while the cleaning component is slidably disposed inside the collecting component.

2. The paraffin-embedded tissue block sectioning device according to claim 1, characterized in that: The collecting component includes a collection bin (300), the outer wall of which is fully fitted with the inner wall of the collection base (103), and handles (301) are provided on both sides of the collection bin (300).

3. The paraffin-embedded tissue block sectioning device according to claim 2, characterized in that: The bottom end face of the collection bin (300) is provided with a placement groove (305), and a bottom plate (304) is provided inside the placement groove (305). The end of the handle (301) passes through the placement groove (305) and is fixedly connected to the bottom plate (304). The thickness of the bottom plate (304) is equal to the inner depth of the placement groove (305).

4. The paraffin-embedded tissue block sectioning device according to claim 3, characterized in that: The front and rear surfaces inside the collection bin (300) are both fixed with slide rails (303), and scrapers (302) are slidably arranged on the inner side of the slide rails (303).

5. The paraffin-embedded tissue block sectioning device according to claim 2, characterized in that: It also includes a knife holder (200), and an integral placement platform (104) is formed inside the material collection base (103). One end of the material collection bin (300) has a concave portion that partially encloses the outside of the placement platform (104). The knife holder (200) is installed at the top of the placement platform (104).

6. The paraffin-embedded tissue block sectioning device according to claim 5, characterized in that: The cutting component includes a blade holder (200) positioned directly below the wax block holder (101), and a blade (201) is mounted on top of the blade holder (200) in front of the wax block holder (101).

7. The paraffin-embedded tissue block sectioning device according to claim 6, characterized in that: A handwheel (102) is also installed on the outside of the body (100), which is connected to the wax block holder (101) in a transmission connection.

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