A closed tabletting and drop-on-dye compounder

Abstract

The utility model discloses a closed type tablet drop dyeing compound machine relates to tablet drop dyeing technical field, including drop dyeing box, and the front side of drop dyeing box is provided with operation cavity, and the inside bottom side limiting sliding of operation cavity is installed with sliding seat, and the upper end surface of sliding seat is provided with tablet groove, the inside sliding of sliding seat is installed with cooling plate, and the inside front side limiting sliding of operation cavity is installed with transparent observation door, and the inside top of operation cavity is set up screw rod with the position of tablet groove going up and down, and both ends of screw rod are fixedly installed with end cover, and the end cover on bottom end is fixedly installed with dyeing needle, and the fixed installation of two end covers has the scale board. Drive worm and gear mechanism through the rotation hand wheel, drive dyeing needle and scale board accurate lifting to set the drop height. The closed operation can effectively isolate dust pollution, guarantee sample pure, and the height control ensures the repeatability of drop impact force, thereby improves the quality stability and experimental success rate of chromosome tablet.

Description

Technical Field

[0001] This utility model relates to the field of sheet-making and drip-dyeing technology, and in particular to a closed-type sheet-making and drip-dyeing composite machine. Background Technology

[0002] Techniques for preparing thin slides of biological material suitable for observation under an optical microscope. While fresh biological material can be observed using simple temporary slides, permanent slides are often prepared according to specific procedures for preservation and future observation. In university biology courses, there are experiments requiring chromosome slide preparation. During slide preparation, cell suspension is first dropped from a designated height to ensure even adhesion to the slide and guarantee experimental accuracy. Additionally, the slide needs to be maintained at approximately 0 degrees Celsius.

[0003] Most existing chromosome preparation dispensing devices employ an open design, which has inherent drawbacks. This open design exposes the slide and cell suspension entirely to the laboratory environment, making them highly susceptible to the dispersal of dust, fibers, and other impurities from the air. These contaminants adhere to the sample surface, interfering with microscopic observation and analysis of chromosomes, and affecting the clarity and accuracy of the results. Furthermore, the lack of precise height adjustment means operators typically rely on experience to roughly control the dispensing distance manually. This prevents the accurate reproduction of the crucial physical impact required for chromosome dispersion, directly leading to significant fluctuations in preparation quality across different batches and even within the same batch. Inconsistent chromosome dispersion reduces the reproducibility and success rate of the experiment.

[0004] To address the aforementioned problems, this utility model proposes a closed-type sheet-making and dyeing composite machine. Utility Model Content

[0005] To address the problems existing in the background technology, this utility model proposes a closed-type sheet-making and dyeing composite machine.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a closed-type sheet preparation and dyeing composite machine, including a dyeing box, an operating chamber on the front side of the dyeing box, a sliding seat slidably installed on the bottom side of the operating chamber, a sheet preparation groove on the upper end face of the sliding seat; a cooling plate slidably installed inside the sliding seat; a transparent observation door slidably installed on the front side of the operating chamber; a screw is raised and lowered on the top side of the operating chamber corresponding to the sheet preparation groove, end caps are fixedly installed at both ends of the screw, a dyeing needle is fixedly installed on the bottom end cap, a ruler is fixedly installed between the two end caps, the ruler penetrates the dyeing box and the two form a sliding fit.

[0007] The present invention is further configured such that the scale on the top surface of the drip dyeing box corresponds to the distance between the needle tip of the dyeing needle and the slide preparation groove.

[0008] The present invention is further configured such that the screw penetrates the top of the dyeing box and the two form a sliding fit; a worm wheel is rotatably installed on the top surface of the operating cavity corresponding to the position of the screw, and the worm wheel is threadedly connected to the screw; a worm is rotatably installed on the top surface of the operating cavity corresponding to the position of the worm wheel, and the worm is meshed with the worm wheel; one end of the worm extends to the outside of the dyeing box and is fixedly installed with a handwheel, and the worm is rotatably connected to the dyeing box.

[0009] The present invention is further configured such that a slot is provided on the front side of the upper end of the sliding seat, and the bottom side of the transparent observation door is inserted into the slot.

[0010] The present invention is further configured such that a hook is rotatably installed at the bottom front side of the transparent observation door, and a fixing ring is fixedly installed at the top front side of the dyeing box, with the hook and the fixing ring engaging.

[0011] The present invention is further configured such that a movable groove is provided on the side wall of the sliding seat, the cooling plate is slidably installed inside the movable groove, and an ice block groove is provided on the upper end of the cooling plate corresponding to the position of the sheet preparation groove.

[0012] The present invention is further configured such that a guide rail is fixedly installed on the inner bottom surface of the operating cavity, and a slider is fixedly installed on the bottom end of the sliding seat, with the slider slidably connected to the guide rail.

[0013] The present invention is further provided that a storage box is fixedly installed at the bottom of the dyeing box.

[0014] Compared with the prior art, the beneficial effects of this utility model are: This closed-loop slide preparation and staining system comprises a staining chamber, a sliding seat, a transparent observation door, a lifting and adjusting mechanism, and a cooling plate. After opening and securing the observation door, the sliding seat is pulled out to place the slide, and ice is added to the cooling plate for pre-cooling. The sliding seat is then pushed back and the sealed observation door is closed. A handwheel drives a worm gear mechanism, precisely raising and lowering the staining needle and ruler to set the drop height. The closed operation effectively isolates dust contamination, ensuring sample purity; height control ensures the repeatability of the drop impact force, thereby improving the quality stability of chromosome preparation and the success rate of experiments. Attached Figure Description

[0015] The present invention will be further described below with reference to the accompanying drawings and embodiments: Figure 1 This is a schematic diagram of the overall structure of this utility model; Figure 2 This is a side view of the structure of this utility model; Figure 3 This utility model Figure 2 Enlarged view of point A in the middle; Figure 4This is a partial cross-sectional view of the present invention. Figure 5 This is a schematic diagram of the internal structure of the drip dyeing box of this utility model.

[0016] Reference numerals: 1. Dyeing box; 2. Operating chamber; 3. Sliding seat; 4. Slide preparation tank; 5. Cooling plate; 6. Transparent observation door; 7. Screw; 8. Dyeing needle; 9. End cap; 10. Ruler plate; 11. Worm gear; 12. Worm; 13. Handwheel; 14. Slot; 15. Hook; 16. Fixing ring; 17. Movable slot; 18. Ice box; 19. Guide rail; 20. Storage box. Detailed Implementation

[0017] It should be noted that, unless otherwise specified, the embodiments and features described in this application can be combined with each other. The present invention will now be described in detail with reference to the accompanying drawings and embodiments.

[0018] It should be noted that, unless otherwise specified, all technical and scientific terms used in this application have the same meaning as commonly understood by one of ordinary skill in the art to which this application pertains.

[0019] In this utility model, unless otherwise stated, the orientations used, such as "up" and "down", usually refer to the direction shown in the accompanying drawings, or to the vertical, perpendicular, or gravitational direction; similarly, for ease of understanding and description, "left" and "right" usually refer to the left and right shown in the accompanying drawings; "inner" and "outer" refer to the inner and outer contours of each component itself, but the above directional terms are not used to limit this utility model.

[0020] Please see Figure 1-5 This utility model provides a technical solution: a closed-type slide preparation and staining composite machine, including a staining box 1. An operating chamber 2 is provided on the front side of the staining box 1. A sliding seat 3 is slidably mounted on the bottom side of the operating chamber 2, and a slide preparation groove 4 for placing glass slides is provided on the upper end surface of the sliding seat 3. A guide rail 19 is fixedly mounted on the bottom surface of the operating chamber 2, and a slider is fixedly mounted on the bottom end of the sliding seat 3, with the slider slidably connected to the guide rail 19. This facilitates the smooth pulling of the sliding seat 3 out of the operating chamber 2 for placing and sampling glass slides, or pushing it into the operating chamber 2 for closed-loop operation.

[0021] Please see Figure 2 and Figure 3A transparent observation door 6 is slidably mounted on the front side of the operating chamber 2. A slot 14 is provided on the front side of the upper end of the sliding seat 3, and the bottom side of the transparent observation door 6 is inserted into the slot 14. A hook 15 is rotatably mounted on the bottom front side of the transparent observation door 6, and a fixing ring 16 is fixedly mounted on the top front side of the staining chamber 1. The hook 15 and the fixing ring 16 are engaged. This achieves reliable sealing of the operating chamber 2, effectively preventing external dust and impurities from contaminating the sample, while the transparent door facilitates observation of the internal operating process.

[0022] Please see Figure 4 and Figure 5 A screw 7 is mounted vertically on the top surface of the operating chamber 2, corresponding to the position of the slide preparation groove 4. The screw 7 passes through the top of the dyeing box 1 and the two are in a sliding fit. A worm gear 11 is rotatably mounted on the top surface of the operating chamber 2, corresponding to the position of the screw 7, and the worm gear 11 is threadedly connected to the screw 7. A worm 12 is rotatably mounted on the top surface of the operating chamber 2, corresponding to the position of the worm gear 11, and the worm 12 is meshed with the worm gear 11. One end of the worm 12 extends to the outside of the dyeing box 1 and is fixedly mounted with a handwheel 13, and the worm 12 is rotatably connected to the dyeing box 1. End caps 9 are fixedly mounted on both the upper and lower ends of the screw 7, and a dyeing needle 8 is fixedly mounted on the bottom end cap 9. A ruler 10 is fixedly mounted between the two end caps 9, passing through the dyeing box 1 and forming a sliding fit. The scale on the top surface of the ruler 10 corresponds to the distance between the needle tip of the dyeing needle 8 and the slide preparation groove 4. The height of the staining needle 8 can be precisely adjusted by turning the handwheel 13, and the dripping height can be precisely controlled by the scale on the ruler 10, ensuring the repeatability and accuracy of the experimental parameters.

[0023] Please see Figure 2 A cooling plate 5 is slidably installed inside the sliding seat 3. A movable groove 17 is provided on the side wall of the sliding seat 3, and the cooling plate 5 is slidably installed inside the movable groove 17. Ice cube slots 18 are provided on the upper end of the cooling plate 5 corresponding to the slide preparation slot 4. This allows the user to easily pull out the cooling plate 5 and place ice cubes in the ice cube slots 18 to pre-cool the slides, thereby optimizing the chromosome fixation effect. A storage box 20 is fixedly installed at the bottom of the staining box 1, providing storage space for related consumables and keeping the workbench tidy.

[0024] Working principle: In use, first slide the transparent observation door 6 upwards to open it, and after raising it to the appropriate position, rotate the hook 15 at the bottom front end to securely engage it with the fixing ring 16 fixed to the top front side of the staining chamber 1, thus stabilizing the transparent observation door 6 in a fully open state, providing a spacious and unobstructed entrance for subsequent operations. Next, grasp the sliding seat 3 and smoothly pull it out of the staining chamber 1 along the guide rail 19 fixed to the bottom surface of the operating chamber 2 until it is fully exposed to the operator. At this point, the prepared clean glass slide can be precisely placed in the slide preparation groove 4 on the upper surface of the sliding seat 3 to ensure that the slide remains fixed in position during subsequent steps. Then, gently pull out the built-in cooling plate 5 from the movable groove 17 on the side wall of the sliding seat 3, fill it with an appropriate amount of ice into the ice block groove 18 corresponding to the slide preparation groove 4, and then push the cooling plate 5 back into its original position inside the movable groove 17, so that the cooling source can continuously provide a uniform low-temperature environment to the glass slide area close to the lower part of the sliding seat 3.

[0025] After completing the slide placement and pre-cooling preparation, grasp the sliding seat 3 again and smoothly push it into the operating chamber 2 along the guide rail 19 until it is fully reset. Then, unfasten the hook 15 and the fixing ring 16, slide the transparent observation door 6 downwards to close it, so that its bottom side is accurately inserted into the slot 14 opened on the front side of the upper end of the sliding seat 3. This not only achieves complete sealing of the operating chamber 2, effectively preventing external contaminants from falling in, but also locks the sliding seat 3 itself inside the staining chamber 1 through the insertion and cooperation of the slot 14 and the transparent observation door 6, preventing it from sliding accidentally. The transparency of the transparent observation door 6 allows the operator to observe the internal condition in real time throughout the closed operation.

[0026] When a drop staining operation is required, turning the handwheel 13 drives the worm gear 12 to rotate, which in turn drives the meshing worm wheel 11 to rotate. Since the worm wheel 11 and the vertically arranged screw 7 form a threaded connection, the rotational motion of the worm wheel 11 is converted into the precise vertical lifting and lowering motion of the screw 7. When the screw 7 moves downward, it drives the end caps 9 fixed at both ends and the staining needle 8 fixed on the bottom end cap 9 to descend synchronously. At the same time, the ruler 10 fixed between the two end caps 9 also moves vertically. By carefully observing the scale indication on the ruler 10 relative to the fixed reference point on the top surface of the drop staining box 1, the operator can accurately know the real-time distance between the tip of the staining needle 8 and the surface of the glass slide placed in the slide preparation groove 4. This allows the operator to precisely adjust the staining needle 8 to the predetermined optimal drop height, ensuring the consistency of the drop impact force and the reliability of the experimental results.

[0027] The embodiments of the present utility model have been described in detail above with reference to the accompanying drawings. However, the present utility model is not limited to the above embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes can be made without departing from the spirit of the present utility model.

Claims

1. A closed-type sheet preparation and dyeing composite machine, comprising a dyeing box (1), characterized in that: The front side of the dyeing box (1) is provided with an operating cavity (2). A sliding seat (3) is slidably installed on the bottom side of the operating cavity (2). A slide preparation groove (4) is provided on the upper end face of the sliding seat (3). A cooling plate (5) is slidably installed inside the sliding seat (3). A transparent observation door (6) is slidably installed on the front side of the operating cavity (2). A screw (7) is raised and lowered on the top side of the operating cavity (2) corresponding to the position of the slide preparation groove (4). End caps (9) are fixedly installed on both the upper and lower ends of the screw (7). A dyeing needle (8) is fixedly installed on the bottom end cap (9). A ruler plate (10) is fixedly installed between the two end caps (9). The ruler plate (10) penetrates the dyeing box (1) and the two form a sliding fit.

2. The closed-type sheet-making and dyeing composite machine according to claim 1, characterized in that: The scale on the top surface of the drip dyeing box (1) corresponds to the distance between the needle tip of the dyeing needle (8) and the slide preparation groove (4).

3. The closed-type sheet-making and dyeing composite machine according to claim 1, characterized in that: The screw (7) passes through the top of the dyeing box (1) and the two form a sliding fit. The top surface inside the operating cavity (2) is rotatably installed with a worm wheel (11) at the position corresponding to the screw (7). The worm wheel (11) is threadedly connected to the screw (7). The top surface inside the operating cavity (2) is rotatably installed with a worm (12) at the position corresponding to the worm wheel (11). The worm (12) is meshed with the worm wheel (11). One end of the worm (12) extends to the outside of the dyeing box (1) and is fixedly installed with a handwheel (13). The worm (12) is rotatably connected to the dyeing box (1).

4. The closed-type sheet-making and dyeing composite machine according to claim 1, characterized in that: The upper front side of the sliding seat (3) is provided with a slot (14), and the bottom side of the transparent observation door (6) is inserted into the slot (14).

5. The closed-type sheet-making and dyeing composite machine according to claim 1, characterized in that: The transparent observation door (6) is rotatably mounted with a hook (15) at the bottom front side, and a fixing ring (16) is fixedly mounted at the top front side of the dyeing box (1). The hook (15) and the fixing ring (16) are engaged.

6. The closed-type sheet-making and dyeing composite machine according to claim 1, characterized in that: The sliding seat (3) has a movable groove (17) on its side wall. The cooling plate (5) is slidably installed inside the movable groove (17). The upper end of the cooling plate (5) has an ice block groove (18) at the position corresponding to the plate preparation groove (4).

7. A closed-type sheet-making and dyeing composite machine according to claim 1, characterized in that: The bottom surface of the operating cavity (2) is fixedly installed with a guide rail (19), and the bottom end of the sliding seat (3) is fixedly installed with a slider, which is slidably connected to the guide rail (19).

8. A closed-type sheet-making and dyeing composite machine according to claim 1, characterized in that: A storage box (20) is fixedly installed at the bottom of the dyeing box (1).

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