Pipette tip head arrangement for a chemiluminescence immunoassay analyzer
Patent Information
- Application Number
- CN202522527894.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Priority Date
- 2025-11-19
- Filing Date
- 2025-11-28
- Publication Date
- 2026-10-30
- Estimated Expiration
- 2035-11-28
AI Technical Summary
[0004]有鉴于此,本实用新型提供一种用于化学发光免疫分析仪的移液器取tip头布置结构,不仅解决了传统布局方式占用空间大的技术问题,而且能够精准能够抓取tip头盒内的每一个tip头
[0019]1、采用本实用新型提供的用于化学发光免疫分析仪的移液器取tip头布置结构,线性移动模组驱动定位组件前后移动,再配合移液器组件进行旋转和升降运动,能够形成多维度的协同运动覆盖,保证移液器组件的枪头可精准到达tip头盒内的每个tip头所在位置,从而实现对每个tip头的精准提取。相较于传统的三维移动模组控制枪头抓取tip头,在抓取效率、机构紧凑性和空间利用率方面具有显著的技术优势。
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Figure CN224921857U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of chemiluminescence immunoassay analyzer technology, specifically to a pipette tip arrangement structure for a chemiluminescence immunoassay analyzer. Background Technology
[0002] As a key device in clinical diagnosis and life science research, one of the core functions of chemiluminescence immunoassay analyzers is to automatically and accurately transfer samples and reagents using pipettes. The automated loading and unloading and recycling of disposable tips that come with the pipettes is a crucial step in ensuring testing efficiency and avoiding cross-contamination.
[0003] In existing technologies, the structure for loading and unloading disposable pipette tips is as follows: the pipette is movably mounted inside the chemiluminescence immunoassay analyzer via an X, Y, Z three-dimensional moving module. The tips are arranged in a rectangular array within a tip holder, which is fixedly mounted at the rear of the analyzer. The three-dimensional moving module controls the movement of the pipette within the space, allowing individual tips to be removed from the tip holder. However, this layout requires the installation of the three-dimensional moving module for the pipette, occupying a large space and hindering the compact and miniaturized design of the chemiluminescence immunoassay analyzer. Therefore, the applicant has redesigned a new tip loading and unloading arrangement structure. Utility Model Content
[0004] In view of this, the present invention provides a pipette tip arrangement structure for a chemiluminescence immunoassay analyzer, which not only solves the technical problem of large space occupation in the traditional layout, but also can accurately pick up each tip in the tip box.
[0005] To achieve the above objectives, the technical solution of this utility model is as follows:
[0006] A pipette tip arrangement structure for a chemiluminescence immunoassay analyzer, the key features of which include a support frame, a positioning component slidably mounted on the support frame, and a linear moving module that drives the positioning component to slide back and forth, wherein the positioning component is used to position the installation tip box;
[0007] A pipette assembly is installed on one side of the support frame. The pipette assembly includes a column, a cantilever fixed to the top of the column, and a pipette tip located at the distal end of the cantilever. The column is capable of rotating in the horizontal plane and moving up and down in the vertical direction.
[0008] With the above structure, the linear motion module drives the positioning component to move back and forth, and then cooperates with the pipette component to rotate and lift, which can form a multi-dimensional coordinated motion coverage, ensuring that the pipette tip can accurately reach the position of each tip in the tip box, thereby achieving accurate extraction of each tip.
[0009] Preferably, the positioning component is a positioning frame that conforms to the outer contour of the tip box. With this structure, the positioning frame can accurately and stably position the tip box, effectively preventing the tip box from shifting during the reciprocating sliding process of the positioning component.
[0010] Preferably, the positioning frame is provided with elastic clamping structures in both the x and y directions. These elastic clamping structures are used to eliminate gaps in the tip box within the positioning frame. This structure ensures that when the tip box is within the positioning frame, all four sidewalls are fully abutted against the frame, thereby guaranteeing the positional accuracy of the tip box's horizontal movement on the top of the support frame and enabling the pipette tip to accurately pick up material.
[0011] Preferably, the positioning frame has mounting notches on two adjacent edges, and each mounting notch has an elastic clamping structure. With this structure, the mounting notches provide stable support for the installation of the elastic clamping structures.
[0012] Preferably, the elastic clamping structure includes a mounting block fixed to the outside of the positioning frame and a pressure plate rotatably mounted on the side of the mounting block. A roller is rotatably mounted on the pressure plate, and an elastic component is provided between the pressure plate and the mounting block. The elastic component applies a force that causes the roller to move closer to the inside of the positioning frame. With this structure, when the tip box is placed in the positioning frame, the continuous elastic force of the elastic component ensures that the roller stably clamps the side of the tip box, effectively eliminating the gap between the tip box and the positioning frame, and further improving the positional accuracy of the tip box's horizontal movement on the top of the support frame.
[0013] Preferably, the support frame has two channels arranged vertically, and the positioning components are slidably disposed at the top of the two channels. This structure is also suitable for chemiluminescence immunoassay analyzers with dual lifting channels, offering the advantage of wide applicability.
[0014] Preferably, the positioning component includes a positioning frame adapted to the outer contour of the tip box and a support plate disposed below the positioning frame. With this structure, the support plate provides support to the bottom of the tip box, preventing it from falling during movement or liquid retrieval. The frame of the positioning frame constrains the tip box, ensuring the accuracy of its forward and backward movement.
[0015] Preferably, the linear motion module includes a first linear motion component and a second linear motion component. The first linear motion component drives the positioning frame to move horizontally along the length of the support frame, and the second linear motion component drives the support plate to move horizontally along the length of the support frame. With this structure, the positioning frame and the support plate can move synchronously or independently. This flexible design allows for coordination with the initial sample introduction of the tip box and subsequent recovery processes, offering the advantage of high versatility.
[0016] Preferably, the first linear motion component is disposed on one side of the support frame. The first linear motion component includes a first driving wheel, a first driven wheel, a first synchronous belt sleeved on the first driving wheel and the first driven wheel, and a first motor driving the first driving wheel to rotate. The first synchronous belt is arranged along the length of the support frame. A first transmission block is provided on one side of the positioning frame, and the first transmission block is fixedly connected to the first synchronous belt. Using the above structure, efficient and precise linear drive can be achieved.
[0017] Preferably, the first linear moving component further includes a first slide rail arranged along the length of the support frame, the first slide rail and the first synchronous belt being arranged vertically at intervals, and the first transmission block slidingly engaging with the first slide rail. With this structure, the rigid guiding effect of the first slide rail effectively limits the lateral offset or swaying of the positioning frame during movement, ensuring that the forward and backward movement of the positioning frame is a stable linear motion.
[0018] Compared with the prior art, the beneficial effects of this utility model are:
[0019] 1. The pipette tip arrangement structure for a chemiluminescence immunoassay analyzer provided by this invention utilizes a linear motion module to drive the positioning component to move back and forth, which, in conjunction with the rotation and lifting motion of the pipette assembly, forms a multi-dimensional coordinated motion coverage. This ensures that the pipette tip can accurately reach the location of each tip within the tip holder, thereby achieving precise extraction of each tip. Compared to traditional three-dimensional motion module control for tip grasping, this design offers significant technical advantages in grasping efficiency, structural compactness, and space utilization.
[0020] 2. By coordinating the horizontal movement of the positioning component and the lifting and rotating movements of the pipette assembly, the efficiency of tip loading and unloading is improved. Furthermore, this structure is suitable for various types of chemiluminescence immunoassay analyzers, and through the synergistic effect of the components, it effectively enhances the automation and operational efficiency of the tip loading process.
[0021] 3. The elastic clamping structure can eliminate the gap between the tip box and the positioning frame, thereby ensuring that the four side walls of the tip box are fully in contact with the positioning frame when it is in the positioning frame. This ensures the positional accuracy of the tip box when it moves horizontally on the top of the support frame, allowing the pipette tip of the pipette assembly to pick up the material accurately. Attached Figure Description
[0022] Figure 1 A schematic diagram of the pipette tip assembly structure;
[0023] Figure 2 A reference diagram showing the usage configuration of a pipette tip arrangement;
[0024] Figure 3 This is a schematic diagram of the top structure of support frame 1;
[0025] Figure 4 This is another structural diagram of the top of support frame 1;
[0026] Figure 5 for Figure 4 A magnified view of a section at point B in the middle;
[0027] Figure 6 To show the top view of tip box A within positioning frame 31;
[0028] Figure 7 A top view of the pipette tip arrangement in use. Detailed Implementation
[0029] The present invention will be further described below with reference to the embodiments and accompanying drawings.
[0030] like Figure 1 and Figure 2 As shown, a pipette tip arrangement structure for a chemiluminescence immunoassay analyzer includes a support frame 1 and a pipette assembly 2, wherein the pipette assembly 2 is located behind the support frame 1. A positioning component 3 and a linear motion module for driving the positioning component 3 to reciprocate are slidably mounted on the support frame 1. The positioning component 3 is used to position and mount the tip box A. The pipette assembly 2 includes a column 22, a cantilever 23 fixed to the top of the column 22, and a pipette tip 24 disposed at the distal end of the cantilever 23. The column 22 is capable of rotating in the horizontal plane and moving vertically. Controlling the lifting and rotation of the column 22 is a well-established existing technology and will not be elaborated upon here.
[0031] Based on the above structural design, by Figure 7As can be seen, the horizontal movement trajectory of the pipette tip 24 of the pipette assembly 2 is an arc. The linear motion module drives the positioning component 3 to move back and forth, and in conjunction with the rotation and lifting motion of the pipette assembly 2, a multi-dimensional coordinated motion coverage is formed, ensuring that the pipette tip of the pipette assembly 2 can accurately reach the position of each tip A1 in the tip box A, thereby achieving accurate extraction of each tip A1. This structural design improves the efficiency of tip loading and unloading through the coordinated horizontal movement of the positioning component 3 and the lifting and rotational movements of the pipette assembly 2.
[0032] Furthermore, such as Figure 4 As shown, the positioning component 3 is a positioning frame 31 that conforms to the outer contour of the tip box. With this design, the positioning frame 31 can accurately and stably position the tip box A, effectively preventing the tip box A from shifting during the reciprocating sliding of the positioning component 3, and ensuring that the tip box A is always in the correct position corresponding to the pipette tip 24 of the pipette assembly 2.
[0033] like Figure 3 and Figure 7 As shown, the positioning frame 31 is provided with elastic clamping structures 6 in both the x and y directions. The elastic clamping structures 6 can eliminate the gap between the tip box A and the positioning frame 31, thereby ensuring that when the tip box A is in the positioning frame 31, the four side walls are completely in contact with the positioning frame 31, thus ensuring the positional accuracy of the tip box A in horizontal movement at the top of the support frame 1, so that the tip 24 of the pipette assembly 2 can accurately pick up the material.
[0034] For example Figure 4 As shown, in this embodiment, the positioning frame 31 has mounting notches 312 on two adjacent frame edges, with the openings of the mounting notches 312 facing upwards. Two sets of elastic clamping structures 6 are provided, each set positioned on one of the two mounting notches 312. This design provides stable support for the installation of the elastic clamping structures 6 on the mounting notches 312. Furthermore, by installing the elastic clamping structures 6 on the mounting notches 312, interference with the extraction of the tip box A can be avoided.
[0035] Combination Figure 4 and Figure 5 As shown, the specific structure of the elastic clamping structure 6 is as follows: The elastic clamping structure 6 includes a mounting block 61 fixed to the outside of the positioning frame 31 and a pressure plate 62 rotatably mounted on the side of the mounting block 61. A roller 63 is rotatably mounted on the pressure plate 62. An elastic component 64 is provided between the pressure plate 62 and the mounting block 61. The elastic component 64 applies a force that causes the roller 63 to move closer to the inside of the positioning frame 31, that is, the roller 63 can pass through the mounting notch 312 and move closer to the inside of the positioning frame 31. (Reference) Figure 6When tip box A is placed in positioning frame 31, the continuous elastic force of elastic component 64 ensures that roller 63 stably presses against the side of tip box A, effectively eliminating the gap between tip box A and positioning frame 31, and further improving the positional accuracy of tip box A in horizontal movement at the top of support frame 1.
[0036] Please refer to Figure 5 The pressure plate 62 is rotatably connected to the mounting block 61 via a connecting shaft 65. For ease of installation, an elastic component 64 is sleeved on the connecting shaft 65. In this embodiment, the elastic component 64 is a torsion spring, which can continuously provide a force to the pressure plate 62 towards the interior of the positioning frame 31 through its own torsional deformation. At the same time, this structural design makes the overall layout of the elastic pressing structure 6 more compact and easier to assemble.
[0037] The pipette tip arrangement structure provided in this embodiment is also applicable to chemiluminescence immunoassay analyzers with dual lifting channels. Please refer to [reference needed]. Figure 2 The support frame 1 has two channels arranged vertically. In this embodiment, the two channels are separated by a partition 11 located in the middle, and the positioning component 3 is slidably disposed on the top of the two channels. In practical applications, one channel is the upward sample feeding channel of the tip head box A, and the other channel is the downward retrieval channel of the tip head box A.
[0038] For details, please refer to Figure 1 The positioning component 3 includes a positioning frame 31 and a support plate 32 that are slidably mounted on the support frame 1. In this embodiment, the positioning frame 31 is adapted to the outer contour of the tip head box A, and the support plate 32 is disposed below the positioning frame 31. Figure 2 As shown, the support plate 32 provides support for the bottom of the tip box A, preventing it from falling during movement or liquid retrieval. The frame of the positioning frame 31 constrains the tip box A, ensuring the accuracy of its forward and backward movement. The cooperation between the positioning frame 31 and the support plate 32 ensures the stability of the tip box A's forward and backward movement, further improving the accuracy and reliability of the pipette assembly 2 in grasping the tip.
[0039] Further, refer to Figure 2 The linear motion module includes a first linear motion component 4 and a second linear motion component 5. The first linear motion component 4 can drive the positioning frame 31 to move horizontally along the length of the support frame 1, and the second linear motion component 5 can drive the support plate 32 to move horizontally along the length of the support frame 1. That is, the positioning frame 31 and the support plate 32 can not only move synchronously, but also move independently. This flexible design can be used in conjunction with the initial sample introduction of the tip head box A and the subsequent recovery process, and has the advantage of strong versatility.
[0040] refer to Figure 3 and Figure 4 The first linear movement component 4 is disposed on one side of the support frame 1. The first linear movement component 4 includes a first driving wheel 41 and a first driven wheel 42 located at both ends of the side of the support frame 1. A first synchronous belt 43 is fitted onto the first driving wheel 41 and the first driven wheel 42, and the first synchronous belt 43 is arranged along the length of the support frame 1. The first linear movement component 4 also includes a first motor 44 that drives the first driving wheel 41 to rotate. A first transmission block 311 extending downwards is provided on the outer side of one side of the positioning frame 31. The lower end of the first transmission block 311 is fixedly connected to the first synchronous belt 43. The first motor 44 drives the first driving wheel 41 to rotate, which in turn drives the first synchronous belt 43 to rotate, thereby moving the positioning frame 31 back and forth. Through gear and synchronous belt transmission, efficient and precise linear drive can be achieved.
[0041] Furthermore, by Figure 3 It can be seen that the first linear moving component 4 also includes a first slide rail 45 arranged along the length of the support frame 1. The first slide rail 45 is arranged vertically and vertically with the first synchronous belt 43, and the first slide rail 45 is located above the first synchronous belt 43. A first slider a is fixedly provided on the inner side of the first transmission block 311, that is, on the side of the first transmission block 311 facing the first slide rail 45. The first slider a slides in cooperation with the first slide rail 45. Through the rigid guiding effect of the first slide rail 45, the lateral offset or sway of the positioning frame 31 during the movement is effectively limited, ensuring that the forward and backward movement of the positioning frame 31 is a stable linear motion, further improving the movement accuracy and running smoothness of the positioning frame 31.
[0042] Depend on Figure 4 As can be seen, to avoid interference between the first linear moving component 4 and the second linear moving component 5, and for the rational layout of the overall structure, the second linear moving component 5 is located on the side opposite to the first linear moving component 4. In this embodiment, the structure and principle of the second linear moving component 5 driving the support plate 32 to move back and forth are the same as those of the first linear moving component 4, and will not be described again here.
[0043] Finally, it should be noted that the above description is merely a preferred embodiment of the present utility model. Those skilled in the art, under the guidance of the present utility model, can make various similar representations without departing from the spirit and claims of the present utility model, and such modifications all fall within the protection scope of the present utility model.
Claims
1. A pipette tip arrangement structure for a chemiluminescence immunoassay analyzer, characterized in that, It includes a support frame (1), a positioning component (3) slidably mounted on the support frame (1), and a linear moving module that drives the positioning component (3) to slide back and forth. The positioning component (3) is used to position the installation tip box. A pipette assembly (2) is installed on one side of the support frame (1). The pipette assembly (2) includes a column (22), a cantilever (23) fixed to the top of the column (22), and a pipette tip (24) located at the far end of the cantilever (23). The column (22) is capable of rotating in the horizontal plane and moving up and down in the vertical direction.
2. The pipette tip arrangement structure for a chemiluminescence immunoassay analyzer according to claim 1, characterized in that: The positioning component (3) is a positioning frame (31) adapted to the outer contour of the tip box.
3. The pipette tip arrangement structure for a chemiluminescence immunoassay analyzer according to claim 2, characterized in that: The positioning frame (31) is provided with elastic clamping structures (6) in both the x and y directions. The elastic clamping structures (6) are used to eliminate the gap between the tip box and the positioning frame (31).
4. The pipette tip arrangement structure for a chemiluminescence immunoassay analyzer according to claim 3, characterized in that: The positioning frame (31) has two adjacent frame edges with mounting notches (312), and each of the two mounting notches (312) has an elastic clamping structure (6).
5. The pipette tip arrangement structure for a chemiluminescence immunoassay analyzer according to claim 4, characterized in that: The elastic clamping structure (6) includes a mounting block (61) fixed on the outside of the positioning frame (31) and a pressure plate (62) rotatably mounted on the side of the mounting block (61). A roller (63) is rotatably mounted on the pressure plate (62). An elastic component (64) is provided between the pressure plate (62) and the mounting block (61). The elastic component (64) applies a force that causes the roller (63) to move closer to the inside of the positioning frame (31).
6. The pipette tip arrangement structure for a chemiluminescence immunoassay analyzer according to claim 1, characterized in that: The support frame (1) has two channels arranged in the vertical direction, and the positioning component (3) is slidably arranged on the top of the two channels.
7. The pipette tip arrangement structure for a chemiluminescence immunoassay analyzer according to claim 6, characterized in that: The positioning component (3) includes a positioning frame (31) adapted to the outer contour of the tip box and a support plate (32) disposed below the positioning frame (31).
8. The pipette tip arrangement structure for a chemiluminescence immunoassay analyzer according to claim 7, characterized in that: The linear motion module includes a first linear motion component (4) and a second linear motion component (5). The first linear motion component (4) is used to drive the positioning frame (31) to move horizontally along the length direction of the support frame (1), and the second linear motion component (5) is used to drive the support plate (32) to move horizontally along the length direction of the support frame (1).
9. The pipette tip arrangement structure for a chemiluminescence immunoassay analyzer according to claim 8, characterized in that: The first linear moving component (4) is disposed on one side of the support frame (1). The first linear moving component (4) includes a first driving wheel (41), a first driven wheel (42), a first synchronous belt (43) sleeved on the first driving wheel (41) and the first driven wheel (42), and a first motor (44) that drives the first driving wheel (41) to rotate. The first synchronous belt (43) is arranged along the length direction of the support frame (1). A first transmission block (311) is provided on one side of the positioning frame (31). The first transmission block (311) is fixedly connected to the first synchronous belt (43).
10. The pipette tip arrangement structure for a chemiluminescence immunoassay analyzer according to claim 9, characterized in that: The first linear moving component (4) further includes a first slide rail (45) arranged along the length of the support frame (1), the first slide rail (45) and the first synchronous belt (43) are arranged vertically at intervals, and the first transmission block (311) slides in cooperation with the first slide rail (45).
