A novel electrospray ion source

Abstract

The utility model discloses a novel electrospray ion source, the lower extreme of waste gas exhaust device is connected with processing cylinder, the outside installation of processing cylinder is connected with the sleeve, and the inside of processing cylinder is provided with the locating ring, the inside of processing cylinder is provided with two groups of activated carbon filter screen above the locating ring symmetry, and the inside of processing cylinder is provided with the limiting ring above activated carbon filter screen, the front surface of ion source cavity is installed with temperature control heating box, the inside symmetry of temperature control heating box is provided with heating pipe, and the outside symmetry of temperature control heating box is provided with the connecting pipe, one end of connecting pipe is communicated with the supplementary heating head, one end of supplementary heating head is connected with the exhaust pipe in the inside of ion source cavity, one end of exhaust pipe is communicated with the shower head, the utility model relates to mass spectrometer technical field, the novel electrospray ion source can carry out temperature control to the air of entering, and can more comprehensive carry out the purpose of spraying hot gas, and the practicality is good.

Description

Technical Field

[0001] This utility model relates to the field of mass spectrometry technology, specifically to a novel electrospray ionization source. Background Technology

[0002] Electrospray ionization (ESI) is a commonly used ion source technique in mass spectrometry, especially in liquid chromatography-mass spectrometry (LC-MS). It works by spraying a liquid sample into charged droplets under high voltage, thereby converting the molecules in the droplets into ions in the gas phase. These ions can then be detected and analyzed by a mass spectrometer.

[0003] Chinese patent discloses a novel electrospray ion source (authorization announcement number CN221960934U). This patented technology includes an electrospray ion source body and an ion source cavity connected to the electrospray ion source body. The ion source cavity is a square body, and ultrasonic speakers are symmetrically arranged on the inner wall of the ion source cavity. The symmetrically arranged ultrasonic speakers form a standing wave in the sound field, and the electrospray ionized by the electrospray ion source body achieves physical deceleration and suspension within the standing wave. This application has the effect of improving the atomization efficiency of the ion source.

[0004] However, most existing electrospray ionization sources directly introduce external drying gas. Since the temperature of this gas cannot be regulated upon entry, unsuitable temperatures can negatively impact the evaporation rate of the solvent droplets. For example, the aforementioned prior art uses this method of directly introducing external drying gas. Therefore, those skilled in the art provide a novel electrospray ionization source to address the problems mentioned in the background section. Utility Model Content

[0005] To address the shortcomings of existing technologies, this invention provides a novel electrospray ion source to solve the problems mentioned in the background section.

[0006] To achieve the above objectives, this utility model is implemented through the following technical solution: a novel electrospray ion source, comprising an ion source cavity, an electrospray ion source body disposed on the upper surface of the ion source cavity, and a waste gas discharge device disposed on the lower surface of the ion source cavity. The lower end of the waste gas discharge device is connected to a processing cylinder. A connecting sleeve is installed on the outside of the processing cylinder, and a positioning ring is disposed inside the processing cylinder. Two sets of activated carbon filters are symmetrically disposed above the positioning ring inside the processing cylinder, and a limit ring is disposed above the activated carbon filters inside the processing cylinder.

[0007] A temperature-controlled heating box is installed on the front surface of the ion source cavity. Heating tubes are symmetrically arranged inside the temperature-controlled heating box, and connecting pipes are symmetrically arranged on the outside of the temperature-controlled heating box. One end of the connecting pipe is connected to an auxiliary heating head. One end of the auxiliary heating head is connected to an exhaust pipe inside the ion source cavity, and one end of the exhaust pipe is connected to a nozzle.

[0008] Preferably, four heating tubes are symmetrically arranged inside the temperature-controlled heating box, and the heating tubes are electric heating tubes.

[0009] Preferably, the temperature-controlled heating box is also equipped with an exhaust fan for drawing out air.

[0010] Preferably, the front surface of the temperature-controlled heating box has an air inlet, the connecting pipe is arranged in an "L" shape on the outside of the temperature-controlled heating box, and the nozzle is a rotating head.

[0011] Preferably, the lower surface of the activated carbon filter is in contact with the upper surface of the positioning ring, and the lower surface of the limiting ring is in contact with the upper surface of the activated carbon filter.

[0012] Preferably, the limiting ring is provided with an external thread on its outer side, and the processing cylinder is provided with an internal thread that engages with the external thread on its inner side.

[0013] Beneficial effects

[0014] This invention provides a novel electrospray ionization source. Compared with the prior art, it has the following advantages:

[0015] 1. This novel electrospray ion source heats and adjusts the air entering the chamber to a suitable temperature through a heating tube inside the temperature-controlled heating chamber. Simultaneously, it connects to an auxiliary heating head via a connecting pipe, and finally enters the nozzle through an exhaust pipe to backflush the charged particle area inside the ion source cavity with hot air. This accelerates the evaporation of solvents and forms even smaller charged droplets. This design allows for temperature control of the incoming air and enables more comprehensive hot air spraying, making it highly practical.

[0016] 2. This novel electrospray ion source, through the arrangement of a treatment cylinder, connecting sleeve, limiting ring, activated carbon filter screen, and positioning ring, uses the positioning ring to limit and position the two sets of activated carbon filter screens. At the same time, the connecting sleeve can connect the treatment cylinder to the exhaust gas discharge device, so that the exhaust gas can be treated through the two sets of activated carbon filter screens when it is discharged. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the structure of a novel electrospray ion source;

[0018] Figure 2 This is a schematic diagram of the temperature-controlled heating box in a novel electrospray ion source;

[0019] Figure 3 This is a schematic diagram of the internal structure of the processing cylinder in a novel electrospray ion source.

[0020] In the diagram: 1. Electrospray ion source body; 2. Ion source chamber; 3. Temperature-controlled heating box; 31. Connecting pipe; 32. Auxiliary heating head; 33. Air inlet; 34. Heating pipe; 35. Exhaust pipe; 36. Nozzle; 4. Waste gas discharge device; 5. Treatment cylinder; 51. Connecting sleeve; 52. Limiting ring; 53. Activated carbon filter; 54. Positioning ring. Detailed Implementation

[0021] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0022] Please see Figure 1-3 This utility model provides a technical solution: a novel electrospray ion source, including an ion source cavity 2, an electrospray ion source body 1 disposed on the upper surface of the ion source cavity 2, and a waste gas discharge device 4 disposed on the lower surface of the ion source cavity 2. The lower end of the waste gas discharge device 4 is connected to a processing cylinder 5. A connecting sleeve 51 is installed on the outside of the processing cylinder 5, and a positioning ring 54 is provided inside the processing cylinder 5. Two sets of activated carbon filter screens 53 are symmetrically arranged above the positioning rings 54 inside the processing cylinder 5, and a limiting ring 52 is provided above the activated carbon filter screens 53 inside the processing cylinder 5.

[0023] A temperature-controlled heating box 3 is installed on the front surface of the ion source cavity 2. Heating tubes 34 are symmetrically arranged inside the temperature-controlled heating box 3, and connecting pipes 31 are symmetrically arranged on the outside of the temperature-controlled heating box 3. One end of the connecting pipe 31 is connected to an auxiliary heating head 32. One end of the auxiliary heating head 32 is connected to an exhaust pipe 35 inside the ion source cavity 2. One end of the exhaust pipe 35 is connected to a nozzle 36.

[0024] exist Figure 2In the middle: four heating tubes 34 are symmetrically arranged inside the temperature-controlled heating box 3, and the heating tubes 34 are electric heating tubes. The temperature-controlled heating box 3 is also equipped with an exhaust fan for extracting air. This arrangement uses the exhaust fan inside the temperature-controlled heating box 3 to extract air and enter the ion source cavity 2. After entering, the heating tubes 34 controlled by the temperature controller heat the air to the required temperature, so that the air entering the ion source cavity 2 can backflush the liquid at a suitable temperature.

[0025] exist Figure 2 In the middle: an air inlet 33 is provided on the front surface of the temperature-controlled heating box 3, and the connecting pipe 31 is set in an "L" shape on the outside of the temperature-controlled heating box 3. The nozzle 36 is a rotating head. This setting allows the ejected air to fully contact the droplets inside the ion source cavity 2 through the rotating head, so as to achieve the purpose of backflushing and improve its efficiency.

[0026] exist Figure 3 In the middle section, the lower surface of the activated carbon filter 53 contacts the upper surface of the positioning ring 54, and the lower surface of the limiting ring 52 contacts the upper surface of the activated carbon filter 53. This arrangement uses the limiting ring 52 and the positioning ring 54 to position the two sets of activated carbon filters 53, ensuring the stability of their connection. In this way, the two sets of activated carbon filters 53 can be used to filter and adsorb the passing air.

[0027] exist Figure 3 The limiting ring 52 has an external thread on its outside and the processing cylinder 5 has an internal thread that engages with the external thread on its inside. This configuration allows the limiting ring 52 to be installed and removed by means of the threaded connection between the limiting ring 52 and the processing cylinder 5, thereby enabling the installation and removal of the activated carbon filter screen 53.

[0028] When the new electrospray ion source is in operation (or use), the sample solution is first introduced from the top of the electrospray ion source body 1. After passing through the carrier gas and high pressure in the ion source structure, charged droplets are formed and atomized and sprayed out from the electrospray needle inside. This is existing technology and will not be discussed in detail here. During spraying, the air can be drawn out by the exhaust fan inside the temperature-controlled heating box 3, and the air entering the interior can be heated and adjusted to a suitable temperature through the heating tube 34. At the same time, the air enters the auxiliary heating head 32 through the connecting pipe 31, and finally enters the nozzle 36 through the exhaust pipe 35 to back-blow the charged particle area inside the ion source cavity 2 with hot air, which accelerates the evaporation of solvent and forms even smaller charged droplets.

[0029] The exhaust gas discharge device 4 is connected to the connecting sleeve 51 by bolts. When the exhaust gas is discharged, it will pass through two sets of activated carbon filter screens 53 for double filtration and adsorption treatment. When the activated carbon filter screen 53 is to be disassembled and replaced, it can be disassembled by rotating the limiting ring 52 inside the processing cylinder 5. This makes it practical.

[0030] Furthermore, any content not described in detail in this specification is existing technology known to those skilled in the art.

Claims

1. A novel electrospray ionization source, characterized in that: The device includes an ion source cavity (2), an electrospray ion source body (1) disposed on the upper surface of the ion source cavity (2), and a waste gas discharge device (4) disposed on the lower surface of the ion source cavity (2). The lower end of the waste gas discharge device (4) is connected to a processing cylinder (5). A connecting sleeve (51) is installed on the outside of the processing cylinder (5), and a positioning ring (54) is provided inside the processing cylinder (5). Two sets of activated carbon filters (53) are symmetrically arranged above the positioning ring (54) inside the processing cylinder (5), and a limiting ring (52) is provided above the activated carbon filters (53) inside the processing cylinder (5). A temperature-controlled heating box (3) is installed on the front surface of the ion source cavity (2). Heating tubes (34) are symmetrically arranged inside the temperature-controlled heating box (3), and connecting pipes (31) are symmetrically arranged on the outside of the temperature-controlled heating box (3). One end of the connecting pipe (31) is connected to an auxiliary heating head (32). One end of the auxiliary heating head (32) is connected to an exhaust pipe (35) inside the ion source cavity (2). One end of the exhaust pipe (35) is connected to a nozzle (36).

2. The novel electrospray ion source according to claim 1, characterized in that: The heating tubes (34) are symmetrically arranged inside the temperature-controlled heating box (3), and the heating tubes (34) are electric heating tubes.

3. The novel electrospray ion source according to claim 1, characterized in that: The temperature-controlled heating box (3) is also equipped with an exhaust fan for drawing out air.

4. The novel electrospray ion source according to claim 1, characterized in that: The front surface of the temperature-controlled heating box (3) is provided with an air inlet (33), the connecting pipe (31) is set in an "L" shape on the outside of the temperature-controlled heating box (3), and the nozzle (36) is a rotating head.

5. A novel electrospray ion source according to claim 1, characterized in that: The lower surface of the activated carbon filter (53) is in contact with the upper surface of the positioning ring (54), and the lower surface of the limiting ring (52) is in contact with the upper surface of the activated carbon filter (53).

6. A novel electrospray ion source according to claim 1, characterized in that: The limiting ring (52) is provided with an external thread on its outside, and the processing cylinder (5) is provided with an internal thread that engages with the external thread on its inside.

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