A gene detection sampler

Abstract

This utility model relates to the field of sampling device technology, specifically a gene detection sampler. It solves the technical problems of existing gene detection samplers, such as easy sample contamination, the need for the sampled person to open their mouth wide, and a small sampling range. The sampler includes a housing with an internal mounting cavity and an opening at one end. A drive rod is mounted on the housing, and a spring piece made of elastic material is installed inside the mounting cavity. The drive rod is connected to the spring piece, which is curved and deformed by compression within the mounting cavity. The drive rod is used to push and pull the spring piece. When the spring piece is pushed out of the mounting cavity through the opening by the drive rod, it returns to its natural shape after being freed from the constraint of the inner wall of the mounting cavity. At this time, the top of the spring piece is higher than the outer wall of the housing, and a sampling head is mounted on the top of the spring piece. The drive rod can drive the spring piece to rotate.

Description

Technical Field

[0001] This utility model relates to the field of sampling equipment technology, specifically a gene detection sampler. Background Technology

[0002] Gene sample collection is a fundamental step in subsequent testing and analysis. Currently, the most common gene sampling method is to obtain human oral epithelial cells, and the sampling tools used are usually cotton swabs or swabs.

[0003] During the sampling process, the operator holds a cotton swab or swab and inserts it into the mouth of the person being sampled. The swab or swab containing the cell sample is then removed from the mouth and transferred to a special sampling box for storage and testing.

[0004] However, this traditional sampling method has significant shortcomings in practical operation. During the removal of the sampling tool from the oral cavity, the cell samples adhering to its surface are highly susceptible to contaminants such as microorganisms and dust from the external environment, leading to sample contamination and affecting the accuracy of subsequent test results. A gene detection sampler disclosed in publication number CN206109392U uses a pushing method to move the sampling crown within the oral cavity for sampling. However, this method has a small movement area for the sampling crown, and both traditional cotton swab and swab sampling methods, as well as comparative pushing sampling methods, require the person being sampled to open their mouth wide for sampling. Utility Model Content

[0005] To address the shortcomings of existing technologies, this invention provides a gene detection sampler that solves the technical problems of sample contamination, the need for the sampled person to open their mouth wide, and the small sampling range of existing gene detection samplers.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a gene detection sampler, comprising a housing, an installation cavity inside the housing, and an opening at one end of the installation cavity; a drive rod is mounted on the housing, and a spring sheet is mounted inside the installation cavity. The spring sheet is made of an elastic material, and the drive rod is connected to the spring sheet. The spring sheet is bent and deformed by compression from the inner wall of the installation cavity; the drive rod is used to push and pull the spring sheet. When the spring sheet is pushed out of the installation cavity through the opening by the drive rod, the spring sheet returns to its natural shape after being freed from the constraint of the inner wall of the installation cavity. At this time, the top of the spring sheet is higher than the outer wall of the housing, and a sampling head is mounted on the top of the spring sheet; the drive rod can drive the spring sheet to rotate.

[0007] Furthermore, the mounting cavity has a compression cavity for storing the spring clip and a storage cavity for storing the sampling head.

[0008] Furthermore, the width of the spring is greater than the width of the sampling head, and the width of the extrusion cavity is greater than the width of the storage cavity.

[0009] Furthermore, a screwing block is provided at the other end of the drive rod away from the spring plate, and the screwing block is used to drive the drive rod to rotate.

[0010] Furthermore, a sliding cavity is provided inside the housing, and the interior of the sliding cavity provides movement space for the screwing block.

[0011] Furthermore, a groove is formed on the outer wall of the housing, and the groove communicates with the sliding cavity.

[0012] Furthermore, a limiting groove is provided on the outer wall of the housing, and a limiting block is provided on the screwing block. The limiting block can slide in the limiting groove, and when the limiting block is aligned with the limiting groove, the spring is aligned with the extrusion cavity.

[0013] Furthermore, it includes a protective cover for sealing the opening of the mounting cavity, the end of the drive rod extends and connects to the protective cover, and the extension length of the drive rod is greater than the length of the spring; a raised edge that mates with the protective cover is provided on the housing and around the opening of the mounting cavity.

[0014] Furthermore, it also includes a protective cover for sealing the opening of the mounting cavity, which can be detachably installed at the opening of the mounting cavity.

[0015] Compared with the prior art, the present invention provides a gene detection sampler with the following advantages: This gene testing sampler, with its housing, mounting cavity, drive rod, spring, and sampling head, allows for easy operation during sampling. The operator places the housing into the subject's mouth, eliminating the need for the subject to open their mouth wide. The drive rod then pushes out a spring-loaded piece, which, after being released from the mounting cavity, returns to its natural shape with a greater degree of curvature. The sampling head at its tip protrudes above the outer wall of the housing. The drive rod rotates the spring-loaded piece, preventing contact between the sampling head and the inner wall of the mouth, effectively expanding the sampling range. After sampling, the drive rod pulls the spring-loaded piece back into the mounting cavity, retracting the sampling head along with the spring-loaded piece. This avoids sample contamination caused by the sampling head being exposed to the outside environment when the housing is removed, ensuring the accuracy of the gene testing results. Attached Figure Description

[0016] Figure 1 This is a three-dimensional structural diagram of the present invention; Figure 2 This is a cross-sectional structural diagram of the present invention; Figure 3 This is a first three-dimensional structural diagram of the present invention without the spring clip installed; Figure 4 This is a schematic diagram of the second three-dimensional structure of the present invention without the spring clip installed; Figure 5 This is a three-dimensional structural diagram of Embodiment 1 of the present utility model; Figure 6 This is a three-dimensional structural diagram of Embodiment 2 of the present invention.

[0017] In the diagram: 1. Housing; 2. Mounting cavity; 3. Drive rod; 4. Spring; 5. Sampling head; 6. Twisting block; 7. Sliding cavity; 8. Slot; 9. Limiting slot; 10. Limiting block; 11. Protective cover; 12. Protruding edge; 201. Extrusion cavity; 202. Storage cavity; Detailed Implementation

[0018] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0019] Please see Figure 1-2 This utility model discloses a gene detection sampler, comprising a housing 1, with an installation cavity 2 extending along its length inside the housing 1. One end of the installation cavity 2 has an opening communicating with the outside, providing a channel for the extension and retraction of a spring 4. A drive rod 3 is movably mounted on the housing 1, and the drive rod 3 is rotatably and slidably connected to the housing 1. One end of the drive rod 3 extends into the installation cavity 2 and is fixedly connected to the spring 4 disposed in the installation cavity 2. The spring 4 is made of a material with good elastic properties (such as plastic, hard rubber, etc.), and the spring 4 is initially bent or tilted upwards.

[0020] Since the height of the internal space of the mounting cavity 2 is less than the height of the spring piece 4, when the spring piece 4 is assembled into the mounting cavity 2, it will be deformed by the squeezing action of the inner wall of the mounting cavity 2 and housed in a compact state within the mounting cavity 2. The drive rod 3 can move in a pushing and pulling motion along the axial direction of the housing 1, thereby driving the spring piece 4 to move within the mounting cavity 2; when the drive rod 3 pushes the spring piece 4 towards the opening of the mounting cavity 2, causing the spring piece 4 to gradually break free from the constraint of the mounting cavity 2, the spring piece 4 will return to its natural curved shape under the action of its own elastic force, at which point the top of the spring piece 4 will protrude from the outer wall of the housing 1.

[0021] A sampling head 5 is fixedly mounted on the top of the spring 4. The sampling head 5 can be thin or protruding, and can be made of materials such as cotton, non-woven fabric, silicone, polyester fiber, or nylon. The sampling head 5 is used to contact and collect epithelial cell samples from the oral cavity of the sampled person. At the same time, the drive rod 3 can also rotate relative to the housing 1. When the drive rod 3 rotates, it will synchronously drive the spring 4 connected to it to rotate, thereby realizing the rotation sampling operation of the sampling head 5 in the oral cavity and increasing the sampling area.

[0022] like Figure 2-3 As shown, the mounting cavity 2 has a compression cavity 201 for storing the spring sheet 4 and a storage cavity 202 for storing the sampling head 5. The width of the spring sheet 4 is greater than the width of the sampling head 5, and the width of the compression cavity 201 is greater than the width of the storage cavity 202. When the spring sheet 4 is pulled back into the mounting cavity 2 by the drive rod 3, the compression cavity 201 only applies force to the spring sheet 4 to deform it. After the sampling head 5 enters the storage cavity 202, it does not contact the inner wall of the storage cavity 202, thus avoiding sample damage caused by friction.

[0023] like Figure 3-4 As shown, a screw block 6 is provided at the other end of the drive rod 3 away from the spring piece 4. The screw block 6 is used to drive the drive rod 3 to rotate, and can also drive the drive rod 3 to slide through the knob block. The main function of the screw block 6 is to increase the force-bearing area of ​​the hand. A sliding cavity 7 is provided inside the housing 1. The sliding cavity 7 provides a movement space for the screw block 6. That is to say, the screw block 6 can move in the sliding cavity 7. A slot 8 communicating with the sliding cavity 7 is provided on the outer wall of the housing 1. The screw block 6 can be screwed through the slot 8.

[0024] A limiting groove 9 parallel to the drive rod 3 is formed on the outer wall of the housing 1, and the limiting groove 9 is connected to the sliding cavity 7 inside the housing 1. A limiting block 10 is fixedly installed on the outer wall of the screwing block 6. The size of the limiting block 10 is adapted to the size of the limiting groove 9, so that the limiting block 10 can be just embedded in the limiting groove 9 and slide along the extension direction of the limiting groove 9. When the operator pushes the limiting block 10 to slide in the limiting groove 9, the cooperation between the limiting block 10 and the limiting groove 9 can guide and limit the sliding direction of the drive rod 3, preventing the drive rod 3 from deviating during the sliding process. When the screwing block 6 is rotated to align the limiting block 10 with the limiting groove 9, the spring piece 4 is also just aligned with the extrusion cavity 201 in the mounting cavity 2. In this way, when the operator pushes and pulls the drive rod 3, it can be ensured that the spring piece 4 accurately enters the extrusion cavity 201 for extrusion deformation.

[0025] The gene detection sampler also includes a protective cover 11 for sealing the opening of the mounting cavity 2, and the protective cover has the following two embodiments.

[0026] Example 1, as Figure 5As shown, the end of the drive rod 3 near the spring 4 extends outward and is fixedly connected to the protective cover 11. The extension length of the drive rod 3 is greater than the length of the spring 4, so that the protective cover 11 is further away from the opening of the mounting cavity 2 than the far end of the spring 4. When the operator pulls the drive rod 3, causing the spring 4 to gradually retract into the compression cavity 201 of the mounting cavity 2, the drive rod 3 will continue to move the protective cover 11 toward the opening of the mounting cavity 2 until the protective cover 11 fits against the opening of the mounting cavity 2, thus sealing the opening of the mounting cavity 2. Meanwhile, a raised edge 12 is integrally formed on the outer periphery of the housing 1 and located at the opening of the mounting cavity 2. The raised edge 12 is adapted to the shape and size of the protective cover 11. The protective cover 11 can be rectangular, circular, or other shapes, as long as it can seal the opening of the mounting cavity 2. When the protective cover 11 is closed at the opening of the mounting cavity 2, the edge of the protective cover 11 can be precisely embedded in the raised edge 12. Through the fit between the inner wall of the raised edge 12 and the outer wall of the protective cover 11, the sealing performance at the opening of the mounting cavity 2 is further improved, preventing external pollutants from entering the mounting cavity 2 and contaminating the sample collected by the sampling head 5.

[0027] Example 2, as Figure 6 As shown, the protective cover 11 can also be detachably installed at the opening of the mounting cavity 2. This can be achieved through methods such as: a snap-fit ​​connection, where an elastic snap is provided on the inner side of the protective cover 11, and a snap-fit ​​groove is opened on the outer peripheral wall of the opening of the mounting cavity 2 of the housing 1. The protective cover 11 is detachably fixed by engaging the elastic snap with the snap-fit ​​groove. Alternatively, the protective cover 1 can be slidably connected, or it can be directly closed. The protective cover 1 is detachable. The operator can first insert the housing 1 into the mouth of the person being sampled to complete the sampling. After the spring 4 and sampling head 5 are retracted into the mounting cavity 2 via the drive rod 3, the protective cover 11 is then closed from the outside at the opening of the mounting cavity 2, preventing external contaminants from entering the mounting cavity and contaminating the sampling head 5.

[0028] In summary, when using this gene detection sampler, the shell 1 is first inserted into the mouth of the person being sampled. The person does not need to open their mouth wide; they only need to gently bite or hold the shell 1, or even slightly open their mouth. Then, the operator pushes the drive rod 3 towards the opening of the mounting cavity 2 using the limiting block. At this time, the spring piece 4 connected to the drive rod 3 is slowly pushed out from the squeezing chamber 201 of the mounting cavity 2. After being freed from the constraint of the squeezing chamber 201, the spring piece 4 returns to its natural bent or raised state under its own elasticity, and the sampling head 5 at its tip protrudes from the outer wall of the shell 1, contacting the inner wall of the person being sampled's mouth. Next, the operator rotates the drive rod 3 using the screw block 6. The drive rod 3 drives the spring piece 4 to rotate synchronously, and the sampling head 5 fully contacts the epithelial tissue during the rotation of the inner wall of the mouth, completing the sample collection.

[0029] After sampling, the operator first rotates the screw block 6 to align the limiting block 10 with the limiting groove 9 on the outer wall of the housing 1. At this time, the spring piece 4 is aligned with the squeezing chamber 201. Then, by pulling the drive rod 3 in the opposite direction, the spring piece 4 enters the installation chamber. Under the squeezing action of the inner wall of the squeezing chamber 201, the spring piece 4 gradually contracts and deforms, smoothly entering the squeezing chamber 201. At the same time, the sampling head 5 at the top of the spring piece 4 enters the storage chamber 202. Since the width of the storage chamber 202 is adapted to the sampling head 5 and is smaller than the width of the squeezing chamber, the sampling head 5 will not contact the inner wall of the storage chamber 202, thus avoiding sample damage. If the protective cover 11 adopts the first embodiment, after the spring piece 4 is fully retracted, the protective cover 11 will move with the drive rod 3 and automatically close at the opening of the installation chamber 2, and be embedded in the protrusion 12 around the opening to achieve a seal. If the protective cover 11 adopts the second embodiment, the operator needs to remove the housing 1 from the inside of the cavity and then assemble the protective cover 11 from the outside to the opening of the installation chamber 2.

[0030] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A gene detection sampler, comprising a housing (1), characterized in that: The housing (1) has an installation cavity (2) inside, and one end of the installation cavity (2) has an opening; a drive rod (3) is installed on the housing (1), and a spring piece (4) is installed in the installation cavity (2). The spring piece (4) is made of elastic material. The drive rod (3) is connected to the spring piece (4). The spring piece (4) is bent and deformed by compression of the inner wall of the installation cavity (2) in the installation cavity (2). The drive rod (3) is used to push and pull the spring piece (4). When the spring piece (4) is pushed out of the installation cavity (2) through the opening by the drive rod (3), the spring piece (4) returns to its natural shape after being freed from the constraint of the inner wall of the installation cavity (2). At this time, the top of the spring piece (4) is higher than the outer wall of the housing (1). A sampling head (5) is installed on the top of the spring piece (4). The drive rod (3) can drive the spring piece (4) to rotate.

2. The gene detection sampler according to claim 1, characterized in that: The mounting cavity (2) has a compression cavity (201) for storing the spring (4) and a storage cavity (202) for storing the sampling head (5).

3. The genetic testing sampler of claim 2, wherein: The width of the spring (4) is greater than the width of the sampling head (5), and the width of the extrusion cavity (201) is greater than the width of the storage cavity (202).

4. The genetic testing sampler of claim 3, wherein: The drive rod (3) is provided with a screw block (6) at the other end away from the spring (4), and the screw block (6) is used to drive the drive rod (3) to rotate.

5. The genetic testing sampler of claim 4, wherein: The housing (1) has a sliding cavity (7) inside, and the interior of the sliding cavity (7) provides movement space for the screw block (6).

6. The genetic testing sampler of claim 5, wherein: A slot (8) is provided on the outer wall of the housing (1), and the slot (8) is connected to the sliding cavity (7).

7. The genetic testing sampler of claim 6, wherein: A limiting groove (9) is provided on the outer wall of the housing (1), and a limiting block (10) is provided on the screw block (6). The limiting block (10) can slide in the limiting groove (9), and when the limiting block (10) is aligned with the limiting groove (9), the spring piece (4) is aligned with the extrusion cavity (201).

8. The genetic testing sampler of claim 7, wherein: Includes a protective cover (11) for sealing the opening of the mounting cavity (2), the end of the drive rod (3) extends and connects to the protective cover (11), and the extension length of the drive rod (3) is greater than the length of the spring (4); a protruding edge (12) that cooperates with the protective cover (11) is provided on the housing (1) and around the opening of the mounting cavity (2).

9. The genetic testing sampler of any one of claims 1-7, wherein: It also includes a protective cover (11) for sealing the opening of the mounting cavity (2), the protective cover (11) being detachably installed at the opening of the mounting cavity (2).

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