An extraction separation device for production of pyrroloquinoline quinone

Abstract

This utility model relates to the field of biochemical production equipment technology, and discloses an extraction and separation device for the production of pyrroloquinoline quinone. It includes a main body, a stirring mechanism fixedly installed inside the main body, and a cleaning mechanism connected to the right side of the main body. The stirring mechanism has a motor driving a rotating shaft that rotates a spiral stirring blade, and a vibration motor is installed inside the rotating shaft. A low-frequency ultrasonic generator is installed at the bottom of the tank lid. The cleaning mechanism has an opening and closing assembly consisting of a pipe clamp, bolts, a handle, and a stop block on the guide pipe. A filter screen is installed inside the guide pipe and connected to a pressure pump and a collection pipe. The stop block controls the opening and closing of the guide pipe and the main body by rotation, and works in conjunction with the pressure pump and collection pipe for online rinsing. This utility model achieves efficient and low-foam extraction through mechanical stirring, vibration, and ultrasonic assistance, and solves the problem of needing to stop and disassemble the pipeline for cleaning through an online isolation rinsing structure, thus improving production efficiency and ease of maintenance.

Description

Technical Field

[0001] This utility model relates to the field of biochemical production equipment technology, and in particular to an extraction and separation device for the production of pyrroloquinoline quinone. Background Technology

[0002] Pyrroloquinoline quinone, as an important bioactive substance, requires extraction and separation processes to obtain a high-purity finished product during production. Existing extraction and separation devices use traditional mechanical stirring methods. The structure of the stirring mechanism is relatively simple. In actual production, in order to ensure the full dissolution of the solute, the operator needs to increase the speed of the stirring motor. However, high-speed mechanical stirring causes strong turbulence inside the solution and entrains air, resulting in a large amount of difficult-to-eliminate foam on the liquid surface. This foam not only occupies the effective volume of the stirring tank, but also aggravates the emulsification of the pyrroloquinoline quinone solution, thereby increasing the difficulty of subsequent separation and purification and reducing the yield of the final product.

[0003] Meanwhile, after long-term operation, a large amount of impurities and residues will accumulate inside the supporting guide pipes and filter components of the extraction and separation device. The existing guide pipes lack an effective isolation and self-cleaning structure with the machine body. When it is necessary to clean the inside of the guide pipes and the filter screen, the maintenance personnel stop production and manually disassemble the guide pipes and filter screens. This cumbersome maintenance method not only consumes a lot of human resources, but also leads to a significant increase in the downtime of the extraction and separation device. In addition, the frequent disassembly and assembly accelerates the wear and aging of the pipe connection parts.

[0004] Therefore, this invention proposes an extraction and separation device for the production of pyrroloquinoline quinone to overcome the shortcomings of the prior art. Utility Model Content

[0005] In view of the problems existing in the extraction and separation device for the production of pyrroloquinoline quinone, such as slow dissolution rate due to traditional mechanical stirring and easy foaming leading to reduced product yield, and the lack of isolation and self-cleaning structure in the guide pipe and filter components, which requires shutdown and disassembly for cleaning and maintenance, which is time-consuming, labor-intensive and costly, this utility model aims to provide an extraction and separation device for the production of pyrroloquinoline quinone with an improved structure that can effectively solve the above problems.

[0006] This invention provides an extraction and separation device for the production of pyrroloquinoline quinone, comprising a body, a stirring mechanism fixedly installed inside the body, and a cleaning mechanism connected to the right side of the body.

[0007] The stirring mechanism includes a stirring tank fixedly installed inside the machine body, a lid on top of the stirring tank, a motor fixedly installed on the top of the lid's outer wall, a rotating shaft connected to the motor's output end, spokes fixed to the bottom of the rotating shaft's outer wall, stirring blades fixed to the outer wall of the spokes, a vibration motor fixedly installed on the bottom of the rotating shaft's inner wall, and a low-frequency ultrasonic generator fixedly installed at the front and rear ends of the lid's bottom. The cleaning mechanism includes a guide pipe connected to the right side of the machine body, a pressure pump connected to the rear end of the guide pipe's left side, a filter screen installed inside the guide pipe, a collection pipe connected to the front side of the guide pipe, a clamp fixed to the outer wall of the guide pipe, a threaded groove in the middle of the clamp's top, a bolt threaded into the threaded groove, a handle fixed to the top of the bolt, and a stop block extending into the guide pipe and fixed to the bottom of the bolt. The motor drives the stirring blades to rotate via the rotating shaft for stirring, while simultaneously assisting extraction with vibrations generated by the vibration motor and ultrasonic waves generated by the low-frequency ultrasonic generator. The handle drives the stop block to rotate via the bolt to control the flow of the guide pipe, and works with the pressure pump and collection pipe to achieve online rinsing of the filter screen.

[0008] Preferably, the rotating shaft has a hollow structure, and the vibration motor is fixedly installed at the bottom of the internal cavity of the rotating shaft. The motor and the vibration motor are electrically connected and configured to start synchronously. The vibration motor drives the rotating shaft and the stirring blade to generate high-frequency vibration.

[0009] Preferably, a rubber pad is embedded in the middle of the bucket lid, and the rotating shaft rotates through the rubber pad and is fixedly connected to the output end of the motor. The rubber pad is configured to buffer the vibration generated by the motor during operation and transmit it to the mixing tank.

[0010] Preferably, the stirring blade has a spiral conical structure, with the upper diameter of the stirring blade being larger than the lower diameter. The stirring blade rotates synchronously with the rotating shaft via spokes to mix the solution in the mixing tank.

[0011] Preferably, the outer diameter of the stop block is adapted to the inner diameter of the guide tube, and the handle is configured to drive the bolt to rotate in the threaded groove, thereby driving the stop block to rotate in the guide tube to block or open the channel between the guide tube and the machine body.

[0012] Preferably, the collection pipe is connected to the guide pipe between the baffle and the filter screen. When the baffle is in a closed state and the pressurizing pump is started, the external water enters the collection pipe and is discharged after being flushed by the pressurizing pump through the filter screen.

[0013] Preferably, the pipe clamp is fitted and fixed on the outer wall of the guide pipe, the threaded groove penetrates the wall of the pipe clamp and extends into the interior of the guide pipe, and the bolt and the threaded groove engage to lock the angle of the stop block.

[0014] Preferably, the low-frequency ultrasonic generator is located inside the mixing tank and is fixed to the lower surface of the tank lid by a connector. The low-frequency ultrasonic generator is used to perform ultrasonic-assisted extraction on the material inside the mixing tank.

[0015] This utility model has the following beneficial effects: 1. This utility model solves the problem of high maintenance costs and low efficiency in the prior art, which usually requires disassembling the equipment to clean the pipes and filters after long-term use of the extraction and separation device by setting a closed stop driven by a rotating handle on the guide pipe and using a pressurizing pump and a collection pipe. It achieves the effect of online isolation cleaning of pipes and filters without disassembling the equipment, effectively preventing the backflow of cleaning liquid into the machine body and achieving directional collection of waste liquid.

[0016] 2. This utility model solves the problems of slow dissolution rate, uneven mixing, and excessive foaming that affect product quality in traditional stirring methods by setting up a spiral stirring blade with a larger upper part and a smaller lower part, combined with a vibration motor inside the rotating shaft and a low-frequency ultrasonic generator at the bottom of the bucket lid. It achieves the effect of accelerating solute dissolution, effectively reducing foaming during stirring, and significantly improving extraction and separation efficiency by using the multi-dimensional synergistic effect of mechanical stirring, high-frequency vibration, and ultrasonic assistance. Attached Figure Description

[0017] Figure 1 This is a perspective view of an extraction and separation device for the production of pyrroloquinoline quinone proposed in this utility model; Figure 2 This is a cross-sectional view of the cleaning mechanism of an extraction and separation device for the production of pyrroloquinoline quinone proposed in this utility model; Figure 3 This is a diagram illustrating the cleaning mechanism of an extraction and separation device for the production of pyrroloquinoline quinone proposed in this utility model; Figure 4 This is a cross-sectional view of the stirring mechanism of an extraction and separation device for the production of pyrroloquinoline quinone proposed in this utility model; Figure 5 This is a partial schematic diagram of the stirring mechanism of an extraction and separation device for the production of pyrroloquinoline quinone proposed in this utility model.

[0018] Legend: 1. Body; 2. Cleaning mechanism; 201. Guide pipe; 202. Pressure pump; 203. Filter screen; 204. Rotary handle; 205. Pipe clamp; 206. Stop block; 207. Bolt; 208. Threaded groove; 209. Collection pipe; 3. Stirring mechanism; 301. Stirring tank; 302. Motor; 303. Rubber pad; 304. Rotating shaft; 305. Low-frequency ultrasonic generator; 306. Stirring blade; 307. Spoke; 308. Vibration motor; 309. Bucket lid. Detailed Implementation

[0019] To make the objectives, technical solutions, and advantages of this utility model clearer, the technical solutions in the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of this utility model, and not all of them. All other embodiments obtained by those skilled in the art based on the embodiments of this utility model without creative effort are within the scope of protection of this utility model.

[0020] Example: Please refer to Figures 1 to 5 This utility model provides an extraction and separation device for the production of pyrroloquinoline quinone, which aims to solve the problems in the prior art where the extraction and separation device requires disassembly of the cleaning pipes and filter screen 203 after long-term use, resulting in high maintenance costs and low efficiency, and the traditional stirring method has a slow dissolution rate and is prone to foaming, thus affecting production efficiency and product quality.

[0021] Please refer to Figure 1 and Figure 2 The extraction and separation device for pyrroloquinoline quinone production includes a body 1, a stirring mechanism 3 fixedly installed inside the body 1, and a cleaning mechanism 2 connected to the right side of the body 1. The stirring mechanism 3 is used for multi-dimensional and efficient mixing and physical vibration-assisted dissolution of the pyrroloquinoline quinone solution. The cleaning mechanism 2 is used to achieve online cleaning of pipes and filter screen 203 and waste liquid collection without disassembling the equipment. Through the organic combination of the body 1, the cleaning mechanism 2 and the stirring mechanism 3, efficient extraction in the production process and convenient cleaning in the maintenance process are achieved.

[0022] Please refer to Figure 1 , Figure 4 and Figure 5The stirring mechanism 3 includes a stirring tank 301 fixedly installed inside the machine body 1. The stirring tank 301 serves as the main reaction vessel for containing the pyrroloquinoline quinone solution to be processed. A lid 309 covers the top opening of the stirring tank 301. A motor 302 is fixedly installed on the top of the outer wall of the lid 309 by welding. The motor 302 serves as a power source to drive subsequent stirring actions. The output end of the motor 302 is fixedly connected to a rotating shaft 304 via a coupling. The rotating shaft 304 extends vertically downward into the depth of the stirring tank 301. Spokes 307 are evenly fixed along the circumferential direction on the bottom of the outer wall of the rotating shaft 304. A stirring blade 306 is fixedly connected to the outer wall of the end. The rotating shaft 304 is driven to rotate by the motor 302, which in turn drives the spokes 307 and the stirring blade 306 to perform circular motion in the mixing tank 301 to achieve mechanical stirring of the solution. The rotating shaft 304 has a hollow structure. A vibration motor 308 is fixedly installed on the bottom of the inner wall of the rotating shaft 304. The vibration motor 308 and the motor 302 are electrically connected through wires and slip rings and are configured to start synchronously. Low-frequency ultrasonic generators 305 are fixedly installed at both the front and rear ends of the bottom inner side of the tank cover 309. The low-frequency ultrasonic generators 305 are located inside the mixing tank 301 and are used to generate ultrasonic waves to assist the extraction process.

[0023] Please refer to Figure 1 , Figure 2 and Figure 3 The cleaning mechanism 2 is integrated into the fluid inlet and outlet path of the body 1. The cleaning mechanism 2 includes a guide pipe 201 connected to the right side wall of the body 1. The guide pipe 201 serves as the main fluid channel and communicates with the interior of the mixing tank 301. A pressure pump 202 is connected to the left rear end of the guide pipe 201. The pressure pump 202 is used to draw external water and provide high-pressure rinsing water flow in cleaning mode. A filter screen 203 is fixedly installed inside the guide pipe 201 to intercept impurities in the fluid. A collection pipe 209 is connected to the front wall of the guide pipe 201 to collect... Pipe 209 is used to discharge waste liquid after cleaning. A pipe clamp 205 is fitted and fixed on the outer wall of the guide pipe 201. A threaded groove 208 that penetrates the pipe wall is vertically opened at the top center of the pipe clamp 205. A bolt 207 is threaded inside the threaded groove 208. A rotating handle 204 that is easy to operate by hand is fixedly connected to the top of the bolt 207. The bottom of the bolt 207 penetrates the pipe wall of the guide pipe 201 and extends into the interior of the guide pipe 201 and is fixedly connected to a stop block 206. The stop block 206 is located in the internal flow channel of the guide pipe 201 and is used to control the opening and closing of the flow channel.

[0024] Please refer to Figure 4 and Figure 5The rotating shaft 304 has a hollow structure, and a vibration motor 308 is fixedly installed on the bottom of the inner wall of the rotating shaft 304. The vibration motor 308 and the motor 302 are configured to start synchronously. When the motor 302 drives the rotating shaft 304 to rotate at high speed in the mixing tank 301, the vibration motor 308 works at the same time and generates high-frequency vibration. The vibration is directly transmitted to the rotating shaft 304, the spokes 307 and the stirring blades 306, so that the stirring blades 306 are accompanied by high-frequency micro-amplitude vibration while performing circumferential shearing motion. The superposition effect of rotation and vibration can effectively destroy the aggregated particles in the solution and accelerate the diffusion and dissolution of the solute.

[0025] Meanwhile, the stirring blade 306 is designed with a spiral conical structure, and the upper diameter of the stirring blade 306 is larger than the lower diameter of the stirring blade 306. The spiral shape with the larger upper part and the smaller lower part can form a spiral vortex from top to bottom in the mixing tank 301 during rotation. This not only increases the stirring contact area, but also effectively suppresses the formation of surface vortices, thereby greatly reducing air entrainment and foam generation, ensuring the stability and efficiency of the stirring process.

[0026] To further enhance the extraction effect, low-frequency ultrasonic generators 305 are fixedly installed at both the front and rear ends of the bottom of the tank lid 309 via brackets. The low-frequency ultrasonic generators 305 are suspended above or immersed in the liquid surface inside the stirring tank 301. When the low-frequency ultrasonic generators 305 are working, the ultrasonic waves generated can produce a cavitation effect in the solution. The microjets and shock waves generated when the cavitation bubbles collapse further break down the cell walls or solid particles, which greatly promotes the release and dissolution of pyrroloquinoline quinone, thereby significantly shortening the processing time of extraction and separation.

[0027] In addition, considering that the motor 302 and the vibration motor 308 will generate large mechanical vibrations when they are working, in order to protect the connection structure of the barrel cover 309 and the machine body 1, a rubber pad 303 is embedded in the middle of the barrel cover 309. The rotating shaft 304 rotates through the center hole of the rubber pad 303 and connects to the output end of the motor 302. The rubber pad 303 effectively absorbs and buffers the vibration energy from the motor 302 and the rotating shaft 304 by utilizing its elastic deformation characteristics, preventing the vibration from being rigidly transmitted to the mixing tank 301 and the external machine body 1, thereby ensuring the stability of the extraction and separation device and extending the service life of the extraction and separation device.

[0028] As a preferred embodiment, in order to achieve convenient on / off control of the guide pipe 201 and prevent the cleaning fluid from flowing back into the machine body 1, please refer to... Figure 2 and Figure 3A pipe clamp 205 is fixedly fitted on the outer wall of the guide pipe 201. A threaded groove 208 is vertically opened at the top center of the pipe clamp 205, extending into the interior of the guide pipe 201. A bolt 207 is installed inside the threaded groove 208. A rotating handle 204 for manual force application is fixedly installed at the top of the bolt 207. The bottom end of the bolt 207 extends through the threaded groove 208 into the inner cavity of the guide pipe 201 and is fixedly connected to a stop block 206. The outer diameter of the stop block 206 is adapted to the inner diameter of the guide pipe 201 and forms a sealing fit. By rotating the rotating handle 204, the bolt 207 is driven to rotate in the threaded groove 208, thereby driving the stop block 206 to rotate synchronously inside the guide pipe 201, realizing the physical blocking or opening of the flow channel of the guide pipe 201. The thread engagement between the bolt 207 and the threaded groove 208 allows the stop block 206 to maintain a fixed angle and self-locking after adjustment.

[0029] As another preferred embodiment, to ensure that wastewater during the cleaning process can be effectively collected and does not contaminate the materials inside the machine body 1, please refer to... Figure 2 The collection pipe 209 is connected to the wall of the guide pipe 201, and the specific connection position of the collection pipe 209 is located between the baffle 206 and the filter screen 203. At the same time, the filter screen 203 is fixedly installed in the section of the guide pipe 201 between the pressurizing pump 202 and the collection pipe 209. This ensures that when the baffle 206 is in a closed state and blocks the connection between the guide pipe 201 and the body 1, the external water source pumped by the pressurizing pump 202 can form a flushing water flow. After the water flows through the filter screen 203 and carries away the intercepted impurities, it is blocked by the baffle 206 and forced to change its flow direction to enter the collection pipe 209 for discharge. This realizes the online backwashing of the filter screen 203 and the inside of the guide pipe 201 and the directional discharge of waste liquid.

[0030] Working principle: Before cleaning the extraction and separation device after prolonged use, manually rotate the handle 204. The handle 204 drives the bolt 207 to rotate within the threaded groove 208 at the top of the clamp 205. Power is transmitted to the stop block 206 at the bottom of the bolt 207. The stop block 206 rotates synchronously within the guide pipe 201. The engagement of the threaded groove 208 with the threaded bolt 207 keeps the stop block 206 at a fixed angle, thus sealing the guide pipe 201 to prevent cleaning liquid from flowing back into the machine body 1. Then, the pressurizing pump 202 connected to the left rear end of the guide pipe 201 is started. The pressurizing pump 202 draws external water into the guide pipe 201. The pressurized water has an increased flow rate and flushes the filter screen 203 set inside the guide pipe 201. The cleaning liquid then flows into the collection pipe 209 connected to the front side of the guide pipe 201. The collection pipe 209 collects the cleaning liquid. The cleaning mechanism 2 can clean the pipe efficiently without disassembly, and reduces the maintenance cost of the extraction and separation device.

[0031] When the extraction and separation device is running, the pyrroloquinoline quinone solution is injected into the stirring tank 301 inside the machine body 1. The motor 302 fixed on the lid 309 is started, and the motor 302 drives the rotating shaft 304 to rotate. The rotating shaft 304 drives the spokes 307 and the stirring blades 306 to rotate synchronously. The design of the stirring blades 306, which are larger at the top and smaller at the bottom, reduces foam generation and increases the stirring rate during stirring. At the same time, the vibration motor 308 inside the rotating shaft 304 starts synchronously with the motor 302. The vibration motor 308 makes the spokes 307 and the stirring blades 306 vibrate at the same frequency during stirring to increase the melting speed. The low-frequency ultrasonic generator 305 at the bottom of the lid 309 works synchronously to use ultrasonic waves to assist extraction. The rubber pad 303 reduces the vibration transmission generated by the motor 302. The stirring mechanism 3 increases the stirring rate and reduces the processing time of the extraction and separation device.

Claims

1. An extraction and separation apparatus for the production of pyrroloquinoline quinone, comprising: The machine body (1) has a stirring mechanism (3) fixedly installed inside it, and a cleaning mechanism (2) is connected to the right side of the machine body (1). The stirring mechanism (3) is characterized in that it includes a stirring tank (301), a lid (309) is provided on the top of the stirring tank (301), a motor (302) is fixedly installed on the top of the outer wall of the lid (309), a rotating shaft (304) is fixedly connected to the output end of the motor (302), a spoke (307) is fixedly connected to the bottom of the outer wall of the rotating shaft (304), and a stirring blade (306) is fixedly connected to the outer wall of the spoke (307). The cleaning mechanism (2) includes a guide pipe (201), a pipe clamp (205) is fixedly installed on the outer wall of the guide pipe (201), a threaded groove (208) is opened at the middle of the top of the pipe clamp (205), a bolt (207) is threaded inside the threaded groove (208), a handle (204) is fixedly connected to the top of the bolt (207), a stop block (206) is fixedly connected to the bottom of the bolt (207), a pressure pump (202) is connected to the left rear end of the guide pipe (201), a filter screen (203) is fixedly installed inside the guide pipe (201), and a collection pipe (209) is connected to the front side of the guide pipe (201).

2. The extraction and separation apparatus for the production of pyrroloquinoline quinone according to claim 1, characterized in that, Low-frequency ultrasonic generators (305) are fixedly installed at both the front and rear ends of the bottom of the bucket lid (309), and the low-frequency ultrasonic generators (305) are located inside the mixing tank (301).

3. The extraction and separation apparatus for the production of pyrroloquinoline quinone according to claim 1, characterized in that, The rotating shaft (304) has a hollow structure, and a vibration motor (308) is fixedly installed on the bottom of the inner wall of the rotating shaft (304).

4. The extraction and separation apparatus for the production of pyrroloquinoline quinone according to claim 1, characterized in that, A rubber pad (303) is embedded in the middle of the bucket lid (309), and the rotating shaft (304) rotates through the rubber pad (303) and connects to the output end of the motor (302).

5. The extraction and separation apparatus for the production of pyrroloquinoline quinone according to claim 1, characterized in that, The stirring blade (306) has a spiral conical structure, and the upper diameter of the stirring blade (306) is larger than the lower diameter of the stirring blade (306).

6. The extraction and separation apparatus for the production of pyrroloquinoline quinone according to claim 1, characterized in that, The filter (203) is located between the pressure pump (202) and the baffle (206).

7. The extraction and separation apparatus for the production of pyrroloquinoline quinone according to claim 1, characterized in that, The outer diameter of the stop block (206) is adapted to the inner diameter of the guide tube (201), and the stop block (206) is rotatably connected in the guide tube (201) by the drive of the handle (204).

8. The extraction and separation apparatus for the production of pyrroloquinoline quinone according to claim 1, characterized in that, The collection pipe (209) is connected to the guide pipe (201) between the baffle (206) and the filter (203).

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