A raw material screening and separation device for pharmaceutical manufacturing

Abstract

This utility model discloses a raw material screening and separation device for pharmaceutical manufacturing, belonging to the field of pharmaceutical processing technology. It includes an outer shell and a screening screen. The outer shell is hollow, forming a screening chamber. An inlet is located at the top center of the screening chamber, and several outlets are located on the sides of the outer shell. A vibration structure is located at the bottom of the outer shell. Several screening holes are perforated on the surface of the screening screen, which are distributed sequentially along the vertical direction inside the screening chamber, with the hole diameter decreasing sequentially. The top surface of the screening screen extends downwards from the center to the edge, reaching the inside of the outlet. The screening screen includes a lower screen and at least one upper screen. A guide funnel is located below each upper screen, with the opening at the bottom of the guide funnel close to the center of the screening screen. This utility model can ensure more thorough separation of pharmaceutical raw materials of different particle sizes, thereby improving screening accuracy.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical processing technology, specifically to a raw material screening and separation device for pharmaceutical manufacturing. Background Technology

[0002] In the pharmaceutical manufacturing process, raw materials are usually pulverized. However, the particle size of the pulverized raw materials is not uniform. Therefore, the pulverized raw materials need to be sieved to ensure that the raw materials have a stable dissolution rate or in vivo absorption effect during subsequent processing or use. If the raw materials need to be further processed into tablets or capsules, raw materials with stable particle size can be more evenly dispersed and ensure stable drug dosage. The equipment used to sieve pharmaceutical raw materials usually performs a single sieve through sieves of different mesh sizes to obtain pharmaceutical raw materials of various specifications. The sieve equipment needs to avoid excessive mixing of pharmaceutical raw materials of different particle sizes.

[0003] Based on the above, Chinese patent document CN107755232A discloses a raw material screening and separation device for biopharmaceuticals, including a support base, a screening body on the upper surface of the support base, a feed inlet on the upper surface of the screening body, several sieve plates inside the screening body, each sieve plate having a through hole in its center, a mounting base at the top of the screening body, a mounting hole in the center of the mounting base, the through hole and the mounting hole being directly opposite each other, a motor on the mounting base, a rotating rod connected to the output shaft of the motor, hubs evenly distributed on the rotating rod, the hubs being connected to the rotating rod by fastening screws, several separation blades on the hubs, a storage box on the right side of the screening body corresponding to the sieve plates, and a door on the front side of the screening body; The aforementioned patent document discloses a device for sieving pharmaceutical raw materials according to particle size. This device sequentially sieves the raw materials using several sieve plates with aperture sizes decreasing in an arithmetic progression from top to bottom. The sieve plates extend downwards at an incline. Larger particles slide down the surface of the sieve plates into a collection box, while smaller particles fall through the through-holes of the sieve plates to the surface of the lower sieve plate, thus separating raw materials of different particle sizes. However, some raw materials fall down through the through-holes near the collection box. Because these materials fall close to the lower collection box, they travel a short distance on the surface of the lower sieve plate and cannot be fully sieved. This easily leads to excessive mixing of raw materials of different particle sizes, preventing them from being fully separated. Therefore, the screening and separation device disclosed in the aforementioned patent document still has room for improvement in terms of fully sieving pharmaceutical raw materials. Utility Model Content

[0004] To address the technical deficiencies in the background technology, this utility model proposes a raw material screening and separation device for pharmaceutical manufacturing, which solves the aforementioned technical problems and meets practical needs. The specific technical solution is as follows: A raw material screening and separation device for pharmaceutical manufacturing includes an outer shell and a screening screen. The outer shell is hollow and forms a screening chamber. The outer shell has a feed inlet at the top center of the screening chamber and several discharge outlets extending into the screening chamber on the side. The bottom of the outer shell has a vibration structure. The screening mesh is provided with at least two pieces, each with a number of screening holes through its surface. The screening mesh is distributed sequentially in the vertical direction inside the screening chamber, and the diameter of the screening holes on the surface of the screening mesh decreases sequentially. The top surface of the screening mesh extends downwards at an angle from the center to the edge, and the inner sides of the plurality of discharge ports are respectively matched with the edge of each screening mesh and the edge of the bottom of the screening chamber. The screening mesh includes a lower screen near the bottom of the screening chamber and at least one upper screen above the lower screen. Each upper screen is provided with a guide funnel below it, and the opening at the bottom of the guide funnel is close to the center of the screening mesh.

[0005] As a further technical solution of this utility model, the top surface of the screening mesh is provided with at least one guide rail, which extends spirally from the center of the screening mesh to the edge.

[0006] As a further technical solution of this utility model, a discharge guide groove is provided between the edge of the screening mesh and the inner wall of the screening chamber. The discharge guide groove surrounds the edge of the screening mesh, and one side of the discharge guide groove extends downward and matches the inner side of the discharge port.

[0007] As a further technical solution of this utility model, a discharge guide plate is provided below the lower screen, and one side of the discharge guide plate extends downward at an angle and matches the inner side of the discharge port.

[0008] As a further technical solution of this utility model, a support rod extending upward is provided at the center of the bottom of the screening chamber, and the support rod is fixedly connected to the center of the screening screen.

[0009] As a further technical solution of this utility model, a base plate is provided below the outer shell, and a plurality of elastic structures are provided between the top of the base plate and the bottom of the outer shell, and a buffer pad layer is provided between the top of the base plate and the vibration structure.

[0010] As a further technical solution of this utility model, the outer side of the discharge port is covered with a discharge baffle.

[0011] The beneficial effects of this utility model are as follows: This utility model discloses a device that can effectively screen and separate pulverized pharmaceutical raw materials. Mechanical vibration is generated through a vibrating structure, and the inclined screening screens ensure the flowability of the pharmaceutical raw materials. Inside the screening chamber, the raw materials undergo multi-stage screening through multiple screening screens with progressively decreasing apertures. After passing through the screening screens, the raw materials are guided by a feed funnel and slide to the center of the top surface of the next screening screen. This ensures that the raw materials move from the center to the edge during screening on each screen surface, avoiding insufficient screening due to short movement distances on the screen surface. This reduces the mixing of pharmaceutical raw materials of different particle sizes and ensures more thorough separation of different particle sizes, thereby improving screening accuracy. Attached Figure Description

[0012] Figure 1 This is a schematic diagram of a raw material screening and separation device used in pharmaceutical manufacturing.

[0013] Figure 2 yes Figure 1 A partial schematic diagram of point A in the middle.

[0014] Figure 3 yes Figure 1 A partial schematic diagram at point B in the middle.

[0015] Figure 4 This is a schematic diagram of the structure of a screening screen used in pharmaceutical raw material screening and separation equipment.

[0016] The components are: 1-outer shell, 11-screening chamber, 12-feed inlet, 13-discharge outlet, 14-discharge guide trough, 15-discharge guide plate, 16-support rod, 17-discharge baffle, 2-screening screen, 21-lower screen, 22-upper screen, 23-guide funnel, 24-guide rail, 3-vibration structure, 4-base plate, 5-elastic structure, and 6-buffer pad. Detailed Implementation

[0017] The embodiments of this utility model will be described below with reference to the accompanying drawings and related examples. The embodiments of this utility model are not limited to the following examples, and this utility model relates to relevant necessary components in this technical field, which should be regarded as well-known technology in this technical field and can be known and mastered by those skilled in this technical field.

[0018] A raw material screening and separation device for pharmaceutical manufacturing includes an outer shell 1 and a screening screen 2. The outer shell 1 is hollow inside and forms a screening chamber 11. The outer shell 1 has a feed inlet 12 at the top center of the screening chamber 11, and a plurality of discharge outlets 13 extending into the screening chamber 11 are provided on the side of the outer shell 1. The bottom of the outer shell 1 is provided with a vibration structure 3. The screening mesh 2 has at least two pieces, each with a number of screening holes through its surface. The screening mesh 2 is distributed sequentially in the vertical direction inside the screening chamber 11, and the diameter of the screening holes on the surface of the screening mesh 2 decreases sequentially. The top surface of the screening mesh 2 extends downwards from the center to the edge, and the inner side of several discharge ports 13 matches the edge of each screening mesh 2 and the bottom edge of the screening chamber 11 one by one. The screening screen 2 includes a lower screen 21 near the bottom of the screening chamber 11 and at least one upper screen 22 above the lower screen 21. Each upper screen 22 is provided with a guide funnel 23 below it, and the opening at the bottom of the guide funnel 23 is close to the center of the screening screen 2.

[0019] This utility model discloses a device that can effectively screen and separate pulverized pharmaceutical raw materials, reducing the mixing of pharmaceutical raw materials of different particle sizes and improving screening accuracy and efficiency. (Refer to...) Figure 1 , Figure 2 , Figure 3 , Figure 4 The screening and separation equipment of this utility model mainly consists of an outer shell 1, a screening screen 2, and a vibration structure 3. The crushed pharmaceutical raw materials enter the screening chamber 11 through the feed inlet 12. The feed inlet 12 can be set in the shape of a funnel so that the pharmaceutical raw materials fall to the center of the top surface of the uppermost screening screen 2. The vibration structure 3 adopts a vibrator that can generate mechanical vibration. The vibration structure 3 generates mechanical vibration and drives the outer shell 1 and the screening screen 2 to vibrate synchronously, so that the pharmaceutical raw materials slide evenly from the center to the edge on the surface of the screening screen 2. The inclined screening screen 2 ensures the flowability of the pharmaceutical raw materials. The closer to the bottom of the screening chamber 11, the smaller the aperture of the screening holes on the surface of the screening screen 2. Particles of different sizes are intercepted by the screening screens 2 with different apertures in sequence and discharged from the corresponding discharge outlet 13. The pharmaceutical raw materials with the smallest particle size pass through the lower screen 21 and are discharged from the discharge outlet 13 at the bottom of the screening chamber 11, thereby realizing the screening and separation of pharmaceutical raw materials of different particle sizes. It should be noted that after passing through the upper screen 22, the pharmaceutical raw materials will be guided by the feed funnel 23 and slide down to the center of the top surface of the lower upper screen 22 or lower screen 21. This ensures that the pharmaceutical raw materials move from the center to the edge when being screened on the surface of each screening screen 2, avoiding insufficient screening due to the short distance the pharmaceutical raw materials move on the surface of the screening screen 2. This reduces the mixing of pharmaceutical raw materials of different particle sizes, ensures thorough separation, and improves screening accuracy.

[0020] As one of the preferred embodiments of this utility model, refer to Figure 4The top surface of the screening mesh 2 is provided with at least one guide rail 24. The guide rail 24 extends spirally from the center to the edge of the screening mesh 2. During the screening of pharmaceutical raw materials on the surface of the screening mesh 2, the guide rail 24 guides the pharmaceutical raw materials from the center to the edge of the screening mesh 2, so that the pharmaceutical raw materials move along the extension direction of the guide rail 24. The movement path of the pharmaceutical raw materials is spiral, which can prolong the path and time of movement of the pharmaceutical raw materials on the top surface of the screening mesh 2, and thus more thoroughly screen the pharmaceutical raw materials.

[0021] As one of the preferred embodiments of this utility model, refer to Figure 1 , Figure 2 , Figure 3 , Figure 4 A discharge guide 14 is provided between the edge of the screening mesh 2 and the inner wall of the screening chamber 11. The discharge guide 14 surrounds the edge of the screening mesh 2. One side of the discharge guide 14 extends downward and matches the inner side of the discharge port 13. Containers for collecting pharmaceutical raw materials of different particle sizes can be set on the outside of the discharge port 13. After the pharmaceutical raw materials move along the top surface of the screening mesh 2 to the edge, they will fall into the discharge guide 14. Under the action of mechanical vibration, these pharmaceutical raw materials will gradually slide along the discharge guide 14 toward the discharge port 13 and finally fall into the container through the discharge port 13. The discharge guide 14 can ensure that the pharmaceutical raw materials intercepted by the screening mesh 2 can be discharged smoothly.

[0022] As one of the preferred embodiments of this utility model, refer to Figure 1 Below the lower screen 21, there is a discharge guide plate 15. One side of the discharge guide plate 15 extends downward at an angle and matches the inside of the discharge port 13. The discharge guide plate 15 makes the bottom of the screening chamber 11 form an inclined surface that faces downward toward the discharge port 13. The pharmaceutical raw materials with the smallest particle size will fall onto the surface of the discharge guide plate 15 after passing through the lower screen 21. Under the action of mechanical vibration, these pharmaceutical raw materials can quickly slide along the discharge guide plate 15 toward the discharge port 13 and complete the discharge.

[0023] As one of the preferred embodiments of this utility model, refer to Figure 1 The bottom center of the screening chamber 11 is provided with an upwardly extending support rod 16. The support rod 16 is fixedly connected to the center of the screening screen 2. The support rod 16 is mainly used to support and fix the screening screen 2, ensuring that the top center of the screening screen 2 protrudes upward so that its top surface is conical or frustum-shaped, thereby forming a downward inclined surface on the top surface of the screening screen 2, ensuring the flowability of pharmaceutical raw materials on the surface of the screening screen 2.

[0024] As one of the preferred embodiments of this utility model, refer to Figure 1A base plate 4 is provided below the outer shell 1. The base plate 4 is used to place the screening and separation equipment stably. Several elastic structures 5 are provided between the top of the base plate 4 and the bottom of the outer shell 1. The elastic structures 5 are preferably springs. A buffer pad 6 is provided between the top of the base plate 4 and the vibration structure 3. The buffer pad 6 is preferably a foam material such as sponge. The vibration structure 3 is located in the center of the bottom of the outer shell 1. When the vibration structure 3 operates and causes the outer shell 1 to vibrate, the vibration amplitude of the side part of the outer shell 1 is relatively large. The elastic structures 5 can play a certain buffering role for the vibration of the side part of the outer shell 1 to avoid excessive vibration amplitude. The buffer pad 6 can play a buffering role between the vibration structure 3 and the base plate 4, and can reduce the noise generated by the vibration structure 3 during operation.

[0025] As one of the preferred embodiments of this utility model, refer to Figure 1 The discharge port 13 is covered with a discharge baffle 17. The discharge baffle 17 is made of knitted fabric. Since the vibration structure 3 will cause the outer shell 1 to vibrate mechanically, when the pharmaceutical raw material is discharged through the discharge port 13, the mechanical vibration may cause the pharmaceutical raw material to splash. The discharge baffle 17 can prevent the pharmaceutical raw material from splashing outward, so that the pharmaceutical raw material can slide down smoothly along the discharge baffle 17.

[0026] In summary, this utility model discloses a device that can effectively screen and separate pulverized pharmaceutical raw materials. Mechanical vibration is generated by the vibration structure 3, and the inclined screening mesh 2 ensures the flowability of the pharmaceutical raw materials. The pharmaceutical raw materials undergo multi-stage screening inside the screening chamber 11 through multiple screening meshes 2 with progressively decreasing apertures. After passing through the screening mesh 2, the pharmaceutical raw materials are guided by the guide funnel 23 and slide down to the center of the top surface of the lower screening mesh 2. This ensures that the pharmaceutical raw materials move from the center to the edge during screening on each layer of screening mesh 2, avoiding insufficient screening due to short movement distances on the screening mesh 2 surface. This reduces the mixing of pharmaceutical raw materials of different particle sizes, ensures thorough separation of pharmaceutical raw materials of different particle sizes, and improves screening accuracy.

[0027] The above description is only a preferred embodiment of the present utility model. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the principle of the present utility model, and these improvements and modifications should also be considered within the protection scope of the present utility model.

Claims

1. A raw material screening and separation device for pharmaceutical manufacturing, comprising an outer shell (1) and a screening screen (2), characterized in that, The outer shell (1) is hollow inside and forms a screening chamber (11). The outer shell (1) has a feed inlet (12) at the top center of the screening chamber (11). The outer shell (1) has several discharge outlets (13) extending into the screening chamber (11) on its side. The outer shell (1) has a vibration structure (3) at its bottom. The sieve (2) is provided with at least two pieces and each of them has a number of sieve holes through its surface. The sieve (2) is distributed sequentially in the vertical direction inside the sieve cavity (11) and the aperture of the sieve holes on the surface of the sieve (2) decreases sequentially. The top surface of the screening mesh (2) extends downward from the center to the edge, and the inner side of several discharge ports (13) matches the edge of each screening mesh (2) and the bottom edge of the screening chamber (11) one by one. The screening mesh (2) includes a lower screen (21) near the bottom of the screening chamber (11) and at least one upper screen (22) above the lower screen (21). Each upper screen (22) is provided with a guide funnel (23) below it. The opening at the bottom of the guide funnel (23) is close to the center of the screening mesh (2).

2. The raw material screening and separation equipment for pharmaceutical manufacturing according to claim 1, characterized in that, The top surface of the screening mesh (2) is provided with at least one guide rail (24), which extends spirally from the center of the screening mesh (2) to the edge.

3. The raw material screening and separation equipment for pharmaceutical manufacturing according to claim 1, characterized in that, A discharge guide groove (14) is provided between the edge of the screening mesh (2) and the inner wall of the screening chamber (11). The discharge guide groove (14) surrounds the edge of the screening mesh (2) and extends downward on one side to match the inner side of the discharge port (13).

4. The raw material screening and separation equipment for pharmaceutical manufacturing according to claim 1, characterized in that, Below the lower screen (21) is a discharge guide plate (15), which extends downward on one side and matches the inside of the discharge port (13).

5. The raw material screening and separation equipment for pharmaceutical manufacturing according to claim 1, characterized in that, The bottom center of the screening chamber (11) is provided with an upwardly extending support rod (16), which is fixedly connected to the center of the screening mesh (2).

6. The raw material screening and separation equipment for pharmaceutical manufacturing according to claim 1, characterized in that, The outer shell (1) is provided with a base plate (4) below it. Several elastic structures (5) are provided between the top of the base plate (4) and the bottom of the outer shell (1). A buffer pad layer (6) is provided between the top of the base plate (4) and the vibration structure (3).

7. The raw material screening and separation equipment for pharmaceutical manufacturing according to claim 1, characterized in that, The discharge port (13) is covered with a discharge baffle (17).

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