A cell engineering cell oscillation device

Abstract

This utility model discloses a cell oscillation device for cell engineering, which includes a base. The base is slidably connected to an internally threaded cylinder via a support plate. A threaded screw is connected inside the internally threaded cylinder, and a U-shaped tooth is formed on one side of the outer wall of the internally threaded cylinder. An eccentric roller is rotatably connected to the upper end of the base plate. A base platform is connected to the top of the eccentric roller, and a toothed groove is formed on the outer wall of the eccentric roller to mesh with the U-shaped tooth. During oscillation, a motor drives a V-shaped support frame to move back and forth and rotates the eccentric roller simultaneously through the internally threaded cylinder. The rotation of the eccentric roller causes the base platform to sway horizontally. The back-and-forth movement of the V-shaped support frame causes an L-shaped fixing frame to move back and forth. The back-and-forth movement of the L-shaped fixing frame drives a rotating shaft connected to a mounting column to rotate through horizontal teeth and gears. The rotation of the rotating shaft causes a fixing strip and a fixing plate to rotate, so that the fixing frame sways horizontally while flipping. By combining two sets of oscillation modes, cells, culture medium, and reagents are mixed evenly, achieving a better oscillation effect.

Description

Technical Field

[0001] This utility model relates to the field of cell oscillation technology, specifically a cell oscillation device for cell engineering. Background Technology

[0002] In the field of cell engineering, the homogeneous mixing of cells with culture medium and reagents is a crucial prerequisite for ensuring cell viability and the accuracy and reproducibility of experimental results, especially in core processes such as cell culture, cell transfection, and cell-reagent reactions. Currently, traditional shaking devices used in cell engineering employ a single shaking mode, leading to uneven mixing of cells with culture medium and reagents, which affects subsequent operations. Utility Model Content

[0003] The purpose of this section is to outline some aspects of the embodiments of this utility model and to briefly introduce some preferred embodiments. Simplifications or omissions may be made in this section, as well as in the abstract and title of this application, to avoid obscuring the purpose of these documents; however, such simplifications or omissions should not be used to limit the scope of this utility model.

[0004] In view of the problems existing in the above and / or existing cell engineering cell oscillation devices, this utility model is proposed.

[0005] Therefore, the purpose of this invention is to provide a cell oscillation device for cell engineering that can simultaneously perform horizontal shaking and flipping shaking during the oscillation process, avoiding problems such as uneven mixing of cells with culture medium and reagents due to a single oscillation mode, which would affect subsequent operations.

[0006] To solve the above-mentioned technical problems, according to one aspect of the present invention, the present invention provides the following technical solution:

[0007] A support plate is fixedly connected to the upper end of the base plate, and an internally threaded cylinder is slidably connected to the support plate. A threaded screw is connected inside the internally threaded hole. A U-shaped tooth is formed on one side of the outer wall of the internally threaded cylinder. An eccentric roller is rotatably connected to the upper end of the base plate. A base platform is connected to the top of the eccentric roller, and a tooth groove is formed on the outer wall of the eccentric roller. The U-shaped tooth meshes with the tooth groove. The internally threaded cylinder can move back and forth by rotating the threaded screw. In turn, the back and forth movement of the U-shaped tooth on the surface of the internally threaded cylinder drives the eccentric roller to rotate. The rotation of the eccentric roller can drive the base platform to move synchronously, realizing the horizontal swaying of the base platform. Mounting columns are fixedly installed on both sides of the upper surface of the base platform, and a fixing plate is provided at the upper end of the base platform. Fixing strips are installed on both sides of the fixing plate, and the fixing plate is rotatably connected to the mounting columns through the fixing strips.

[0008] As a preferred embodiment of the cell engineering cell oscillation device of this utility model, a rotating shaft is provided on the side of the fixing strip away from the fixing plate. The rotating shaft is rotatably connected to the mounting column. A gear is installed at the end of the rotating shaft. An L-shaped fixing frame is provided on one side of the outer wall of the mounting column. An annular opening is opened on the upper surface of the L-shaped fixing frame, and the annular opening passes through the L-shaped fixing frame. A horizontal tooth is opened at the lower end of the annular opening. The horizontal tooth meshes with the gear. The gear can be driven to rotate by moving the L-shaped fixing frame back and forth, and then the rotating shaft drives the fixing strip and the fixing plate to rotate.

[0009] As a preferred embodiment of the cell engineering cell oscillation device of this utility model, the upper end of the eccentric column wheel is provided with an annular boss, the lower end of the base is provided with an annular recess, and support columns are provided around the base. The eccentric column wheel is rotatably connected to the annular recess of the base through the annular boss.

[0010] As a preferred embodiment of the cell engineering cell oscillation device of this utility model, a V-shaped support frame is fixedly installed at the end of the internal threaded cylinder, and sliding rods are provided at both ends of the V-shaped support frame. The V-shaped support frame and the L-shaped fixed frame are slidably connected through the sliding rods.

[0011] As a preferred embodiment of the cell engineering cell oscillation device described in this utility model, a motor is fixedly installed on the outer wall of the rear end of the base. The power output end of the motor is fixedly connected to the threaded screw. The rotation of the motor can synchronously drive the threaded screw to rotate. The motor can control the forward and reverse movement of the internal threaded cylinder by driving the threaded screw to rotate forward and reverse. The forward and backward movement of the internal threaded cylinder can drive the eccentric column wheel to rotate through the meshing of the U-shaped teeth and the tooth groove, and can also drive the V-shaped support frame to move forward and backward at the same time. The rotation of the eccentric column wheel can cause the base to sway horizontally.

[0012] As a preferred embodiment of the cell engineering cell oscillation device of this utility model, the fixed plate has dovetail slides at both ends, and the fixed strip has a dovetail groove on the side near the fixed plate, and the dovetail slides are slidably connected to the dovetail groove.

[0013] As a preferred embodiment of the cell engineering cell oscillation device described in this utility model, an annular groove is provided on the surface of the rotating shaft near the inner side of the gear, and the annular groove is slidably connected to the annular opening of the fixing frame.

[0014] As a preferred embodiment of the cell engineering cell oscillation device described in this utility model, a limiting groove is formed on the surface of the base plate, and the support column is slidably connected to the limiting groove.

[0015] Compared with the prior art, the beneficial effects of this utility model are as follows: During the oscillation process, the motor rotation drives the threaded screw to rotate, which in turn drives the internal threaded cylinder to move back and forth, simultaneously driving the V-shaped support frame to move back and forth and the eccentric column wheel to rotate. The rotation of the eccentric column wheel can drive the base to sway horizontally, and the back and forth movement of the V-shaped support frame can drive the L-shaped fixing frame to move back and forth. The back and forth movement of the L-shaped fixing frame drives the rotating shaft connected to the mounting column to rotate through the meshing of horizontal teeth and gears. The rotation of the rotating shaft can drive the fixing strip and fixing plate to rotate, realizing that the fixing frame sways horizontally while flipping. By combining the two sets of oscillation modes, uniform mixing of cells, culture medium and reagents is achieved, resulting in a better oscillation effect. Attached Figure Description

[0016] To more clearly illustrate the technical solutions of the embodiments of this utility model, the present utility model will be described in detail below with reference to the accompanying drawings and detailed embodiments. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort. Among them:

[0017] Figure 1 This is a schematic diagram of the overall structure of a cell engineering cell oscillation device according to the present invention;

[0018] Figure 2 This is a partial cross-sectional view of the overall structure of a cell engineering cell oscillation device according to the present invention;

[0019] Figure 3 This is a schematic diagram of the overall structure of a cell engineering cell oscillation device of this utility model, without its outer shell.

[0020] Figure 4 This is a side sectional view of the overall structure of a cell engineering cell oscillation device according to the present invention;

[0021] Figure 5 This is a front sectional view of the overall structure of a cell engineering cell oscillation device according to this utility model;

[0022] Figure 6 This utility model relates to a cell oscillation device for cell engineering. Figure 3 Enlarged view of part A in the image;

[0023] Figure 7 This utility model relates to a cell oscillation device for cell engineering. Figure 5 Enlarged view of part B in the image;

[0024] Figure 8 This utility model relates to a cell oscillation device for cell engineering. Figure 5 Enlarged view of section C in the image;

[0025] In the diagram: 1. Base; 1a. Support plate; 1b. Limiting groove; 2. Motor; 3. Threaded screw; 4. Internal threaded cylinder; 4a. U-shaped tooth; 5. Eccentric column wheel; 5a. Tooth groove; 5b. Annular boss; 6. Base platform; 6a. Annular notch; 6b. Mounting column; 6c. Support column; 7. V-shaped support frame; 7a. Slide rod; 8. L-shaped fixing frame; 9. Gear; 10. Fixing strip; 10a. Dovetail groove; 11. Fixing plate; 11a. Dovetail slide bar. Detailed Implementation

[0026] To make the above-mentioned objectives, features and advantages of this utility model more apparent and understandable, the specific embodiments of this utility model will be described in detail below with reference to the accompanying drawings.

[0027] Secondly, this utility model is described in detail with reference to the schematic diagrams. When describing the embodiments of this utility model, for ease of explanation, the cross-sectional views illustrating the device structure may be partially enlarged, not adhering to the usual scale. Furthermore, the schematic diagrams are merely examples and should not limit the scope of protection of this utility model. In addition, actual manufacturing should include the three-dimensional spatial dimensions of length, width, and depth.

[0028] To make the objectives, technical solutions, and advantages of this utility model clearer, the embodiments of this utility model will be described in further detail below with reference to the accompanying drawings.

[0029] This invention provides a cell oscillation device for cell engineering. During the oscillation process, the device can simultaneously perform horizontal shaking and flipping shaking, avoiding problems such as uneven mixing of cells with culture medium and reagents due to a single oscillation mode, which would affect subsequent operations.

[0030] Figures 1-8 The diagram shown is an overall structural schematic of one embodiment of a cell engineering cell oscillation device according to this utility model. Please refer to [link / reference]. Figures 1-8 This embodiment describes a cell engineering cell oscillation device.

[0031] refer to Figure 1 , Figure 3 , Figure 4 , Figure 6The base 1 has a support plate 1a fixedly connected to its upper end. The support plate 1a is slidably connected to an internally threaded cylinder 4. A threaded screw 3 is connected inside the internally threaded hole 4. A U-shaped tooth 4a is provided on one side of the outer wall of the internally threaded cylinder 4. An eccentric roller 5 is rotatably connected to the upper end of the base 1. A base platform 6 is connected to the top of the eccentric roller 5. A tooth groove 5a is provided on the outer wall of the eccentric roller 5. The U-shaped tooth 4a meshes with the tooth groove 5a. The internally threaded cylinder 4 can move back and forth by rotating the threaded screw 3. In turn, the U-shaped tooth 5a on the surface of the internally threaded cylinder 4 moves back and forth, which drives the eccentric roller 5 to rotate. The rotation of the eccentric roller 5 can drive the base platform 6 to move synchronously, realizing the horizontal swaying of the base platform 6. Mounting columns 6b are fixedly installed on both sides of the upper surface of the base platform 6. A fixing plate 11 is provided at the upper end of the base platform 6. Fixing strips 10 are installed on both sides of the fixing plate 11. The fixing plate 11 is rotatably connected to the mounting columns 6b through the fixing strips 10.

[0032] The above scheme is adopted as follows: A support plate 1a, which provides support, guidance, and restriction, is fixedly connected to the upper end of the base plate 1. An internally threaded cylinder 4, which transmits power, is slidably connected to the support plate 1a. The internally threaded cylinder 4 is threadedly connected to a threaded screw 3, which transmits power. A U-shaped tooth 4a, which transmits power, is provided on one side of the outer wall of the internally threaded cylinder 4. An eccentric roller 5, which reciprocates, is rotatably connected to the upper end of the base plate 1. A base platform 6, which provides support and load-bearing, is rotatably connected to the top of the eccentric roller 5. A toothed groove 5a, which receives power, is provided on the outer wall of the eccentric roller 5. The U-shaped tooth 4a communicates with the toothed groove 5a. The meshing transmits power, and the rotation of the threaded screw 3 allows the internal threaded cylinder 4 to move back and forth under the constraint of the support plate 1a. The internal threaded cylinder 4 moves back and forth, and the U-shaped teeth 4a on the cylinder wall surface mesh with the tooth groove 5a to drive the eccentric column wheel 5 to rotate. At the same time, the rotation of the eccentric column wheel 5 can drive the base 6, which plays a supporting and bearing role, to move synchronously, so as to realize the horizontal swaying of the base and achieve the oscillation effect. The upper surface of the base 6 is equipped with mounting columns 6b on both sides for supporting and positioning, and the upper end of the base 6 is provided with a fixing plate 11 for fixing the container. The fixing plate 11 is rotatably connected to the mounting columns 6b through the fixing strip 10, which plays a connecting role.

[0033] refer to Figure 1 , Figure 3 , Figure 5 A rotating shaft 10b is provided on the side of the fixing strip 10 away from the fixing plate 11. The rotating shaft 10b is rotatably connected to the mounting column 6b. A gear 9 is installed at the end of the rotating shaft 10b. An L-shaped fixing bracket 8 is provided on one side of the outer wall of the mounting column 6b. An annular opening is provided on the upper surface of the L-shaped fixing bracket 8, and the annular opening passes through the L-shaped fixing bracket 8. A horizontal tooth is provided at the lower end of the annular opening. The horizontal tooth meshes with the gear 9. The gear 9 can be driven to rotate by moving the L-shaped fixing bracket 8 back and forth. In turn, the rotating shaft 10b drives the fixing strip 10 and the fixing plate 11 to rotate.

[0034] Using the above scheme: the fixing strip 10 is rotatably connected to the mounting column 6b via a rotating shaft 10b located on the side away from the fixing plate 11. A gear 9 is installed at the end of the rotating shaft 10b to receive power. An L-shaped fixing bracket 8 with an annular opening is provided on one side of the outer wall of the mounting column 6b. A horizontal tooth is provided on the lower surface of the annular opening of the L-shaped fixing bracket 8 to transmit power. The L-shaped fixing bracket 8, which moves back and forth, can drive the gear 9 to rotate by meshing with the horizontal tooth. The rotating shaft 10b and the gear 9 can rotate synchronously, which can realize the flipping motion of the fixing strip 10 and the fixing plate 11.

[0035] refer to Figure 5 , Figure 7 An annular boss 5b is provided at the upper end of the eccentric column wheel 5, and an annular recess 6a is provided at the middle of the lower end of the base 6. Support columns 6c are provided around the base 6. The eccentric column wheel 5 is rotatably connected to the annular recess 6a of the base 6 through the annular boss 5b.

[0036] Using the above scheme: the eccentric column wheel 5 is rotatably connected to the annular boss 5b at the upper end for positioning and the annular recess 6a at the lower middle of the base 6 for guiding and limiting.

[0037] refer to Figure 2 , Figure 4 The internal threaded cylinder 4 is fixedly installed with a V-shaped support frame 7 at its end. The V-shaped support frame 7 has slide rods 7a at both ends. The V-shaped support frame 7 and the L-shaped fixed frame 8 are slidably connected through the slide rods 7a.

[0038] The above scheme is adopted: a V-shaped support frame 7 is fixedly installed at the end of the internal threaded cylinder 4 to provide support and transmit power. The V-shaped support frame 7 and the L-shaped fixed frame 8 are slidably connected by a slide rod 7a that provides guidance and support.

[0039] refer to Figures 1-5 A motor 2 is fixedly installed on the outer wall of the rear end of the base 1. The power output end of the motor 2 is fixedly connected to the threaded screw 3. The rotation of the motor 2 can synchronously drive the threaded screw 3 to rotate. The motor 2 can control the forward and reverse rotation of the threaded screw 3 to move the internal threaded cylinder 4 back and forth. The forward and backward movement of the internal threaded cylinder 4 can drive the eccentric column wheel 5 to rotate through the meshing of the U-shaped teeth 4a and the tooth groove 5a. At the same time, it can drive the V-shaped support frame 7 to move back and forth. The rotation of the eccentric column wheel 5 can cause the base 6 to sway horizontally.

[0040] The above scheme is adopted: a motor 2, which serves as a power source, is fixedly installed on the outer wall of the rear end of the base 1. The threaded screw 3, which transmits power, is fixedly connected to the power output end of the motor 2 to achieve synchronous rotation. When the motor 2 rotates forward, it drives the threaded screw 3 to rotate forward, controlling the internal threaded cylinder 4 to move forward. When the motor 2 rotates in reverse, it drives the threaded screw 3 to rotate in reverse, controlling the internal threaded cylinder 4 to move backward. The forward and backward movement of the internal threaded cylinder 4 can simultaneously drive the eccentric column wheel 5 to rotate and the V-shaped support frame 7 to move forward and backward. The rotation of the eccentric column wheel 5 can drive the base 6 to sway horizontally, achieving a horizontal oscillation effect.

[0041] refer to Figure 5 , Figure 8 The fixed plate 11 has dovetail slides 11a at both ends, and the fixed strip 10 has a dovetail groove 10a on the side near the fixed plate 11. The dovetail slides 11a and the dovetail groove 10a are slidably connected.

[0042] The above scheme is adopted: the dovetail slides 11a, which serve to fix and guide, are opened at both ends of the fixed plate 11 and the dovetail grooves 10a, which serve to position and limit, are opened on the side of the fixed strip 10 near the fixed plate 11.

[0043] refer to Figure 5 An annular groove is provided on the surface of the rotating shaft 10b near the inner side of the gear 9, and the annular groove is slidably connected to the annular opening of the fixing frame 8.

[0044] Using the above scheme: the rotating shaft 10b is slidably connected to the annular opening of the fixed frame 8 through an annular groove on the surface near the inner side of the gear 9, which serves as a limiting function. Through the cooperation of the annular groove and the annular opening, the rotating shaft can drive the fixed frame 8 to move left and right.

[0045] Referring to the figure, a limiting groove 1b is formed on the surface of the base plate 1, and the support column 6c is slidably connected to the limiting groove 1b.

[0046] The above scheme is adopted: the base plate 1 has a limiting groove 1b that serves as a guide and limit, and the support column 6c that serves as a support is slidably connected to the limiting groove 1b.

[0047] Although the present invention has been described above with reference to embodiments, various modifications can be made and components can be replaced with equivalents without departing from the scope of the present invention. In particular, as long as there is no structural conflict, the features in the embodiments disclosed in this invention can be combined with each other in any way. The lack of an exhaustive description of these combinations in this specification is merely for the sake of brevity and resource conservation. Therefore, the present invention is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims.

Claims

1. A cell engineering cell shaking device, characterized by, The base (1) includes a base plate (1), on which a support plate (1a) is fixedly connected to the upper end. An internally threaded cylinder (4) is slidably connected to the support plate (1a). A threaded screw (3) is connected inside the internally threaded cylinder (4). A U-shaped tooth (4a) is provided on one side of the outer wall of the internally threaded cylinder (4). An eccentric wheel (5) is rotatably connected to the upper end of the base plate (1). A base platform (6) is connected to the top of the eccentric wheel (5), and a toothed groove (5a) is provided on the outer wall of the eccentric wheel (5). The U-shaped tooth (4a) meshes with the toothed groove (5a), and the threaded screw (3)... 3) Rotation can make the internal threaded cylinder (4) move back and forth, and then drive the eccentric column wheel (5) to rotate through the U-shaped teeth (4a) on the surface of the internal threaded cylinder (4). The rotation of the eccentric column wheel (5) can drive the base (6) to move synchronously, so as to realize the horizontal sway of the base (6). Mounting columns (6b) are fixedly installed on both sides of the upper surface of the base (6), and a fixing plate (11) is provided at the upper end of the base (6). Fixing strips (10) are installed on both sides of the fixing plate (11). The fixing plate (11) is rotatably connected to the mounting column (6b) through the fixing strips (10).

2. A cell engineering cell agitating device according to claim 1, wherein A rotating shaft (10b) is provided on the side of the fixing strip (10) away from the fixing plate (11). The rotating shaft (10b) is rotatably connected to the mounting column (6b). A gear (9) is installed at the end of the rotating shaft (10b). An L-shaped fixing frame (8) is provided on one side of the outer wall of the mounting column (6b). An annular opening is provided on the upper surface of the L-shaped fixing frame (8), and the annular opening passes through the L-shaped fixing frame (8). A horizontal tooth is provided at the lower end of the annular opening. The horizontal tooth meshes with the gear (9). The gear (9) can be driven to rotate by moving the L-shaped fixing frame (8) back and forth. Then, the rotating shaft (10b) drives the fixing strip (10) and the fixing plate (11) to rotate.

3. A cell engineering cell agitator according to claim 2, wherein The eccentric column wheel (5) has an annular boss (5b) at its upper end, and the base (6) has an annular recess (6a) at its lower middle part. Support columns (6c) are provided around the base (6). The eccentric column wheel (5) is rotatably connected to the annular recess (6a) of the base (6) through the annular boss (5b).

4. The cell engineering cell agitator apparatus of claim 3, wherein, The internal threaded cylinder (4) is fixedly installed with a V-shaped support frame (7) at its end. The V-shaped support frame (7) is provided with slide rods (7a) at both ends. The V-shaped support frame (7) and the L-shaped fixed frame (8) are slidably connected through the slide rods (7a).

5. A cell engineering cell agitator apparatus as claimed in claim 4, wherein, A motor (2) is fixedly installed on the outer wall of the rear end of the base (1). The power output end of the motor (2) is fixedly connected to the threaded screw (3). The rotation of the motor (2) can synchronously drive the threaded screw (3) to rotate. The motor (2) can control the internal threaded cylinder (4) to move back and forth by driving the threaded screw (3) to rotate forward and reverse. The internal threaded cylinder (4) can drive the eccentric roller (5) to rotate by meshing the U-shaped teeth (4a) and the tooth groove (5a). It can also drive the V-shaped support frame (7) to move back and forth at the same time. The rotation of the eccentric roller (5) can drive the base (6) to sway horizontally.

6. A cell engineering cell agitator apparatus as claimed in claim 5, wherein, The fixed plate (11) has dovetail slides (11a) at both ends, and the fixed strip (10) has a dovetail groove (10a) on the side near the fixed plate (11). The dovetail slides (11a) are slidably connected to the dovetail groove (10a).

7. A cell engineering cell agitating device according to claim 6, wherein The rotating shaft (10b) has an annular groove on its surface near the inner side of the gear (9), and the annular groove is slidably connected to the annular opening of the fixing frame (8).

8. A cell engineering cell agitating device according to claim 7, wherein The base (1) has a limiting groove (1b) on its bottom plate surface, and the support column (6c) is slidably connected to the limiting groove (1b).

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