A rapid tissue sample collection device for electron microscopy

Abstract

This utility model discloses a rapid tissue sample collection device for electron microscopy, belonging to the field of sample collection. It includes a connecting rod with a conical block fixedly connected to its bottom and a fixing plate fixedly connected to the connecting rod. A sleeve is slidably connected to the outer surface of the connecting rod, and a conical rim is fixedly connected to the bottom of the sleeve, corresponding to the conical block. Through the arrangement of the conical block, sleeve, and conical rim, not only can multiple types of samples be collected, but also mixed samples of different types can be collected simultaneously. Furthermore, it prevents samples from getting stuck between the sleeve and the conical block during sampling, thus avoiding affecting the seal between them. This increases the applicability of the sampling device, making it more convenient to use and accelerating the sampling speed. The sleeve can be fixed by the vertical plate, insert rod, and moving block, facilitating subsequent cleaning and disinfection of the internal components of the sampling device, allowing for reuse.

Description

Technical Field

[0001] This utility model relates to the field of sample collection technology, specifically a rapid tissue sample collection device for electron microscopy. Background Technology

[0002] An electron microscope, also known as an electron microscopy, is a high-resolution microscopic observation tool that uses an electron beam to replace visible light for imaging. It is mainly used to observe the microscopic morphology, ultrastructure, and composition of samples and is widely used in materials science, biomedicine, semiconductors, and other fields.

[0003] When conducting experiments using an electron microscope to observe samples, it is necessary to sample the samples. Some experimental samples may contain both solids and liquids, requiring sampling of both. However, the common sampling devices currently available have relatively simple structures and can mostly only sample the same type of sample. For example, droppers, scissors, and tweezers are used for both liquids and solids. This requires the use of multiple sampling tools, which must be performed separately, making the operation cumbersome and time-consuming, and hindering rapid sample collection.

[0004] Therefore, this invention provides a rapid tissue sample collection device for electron microscopy to solve the above problems. Utility Model Content

[0005] (a) Technical problems to be solved

[0006] This invention provides a rapid tissue sample collection device for electron microscopy, which aims to solve the problems mentioned in the background art.

[0007] (II) Technical Solution

[0008] To achieve the above objectives, this utility model provides the following technical solution:

[0009] A rapid tissue sample collection device for electron microscopy includes a connecting rod, a conical block fixedly connected to the bottom of the connecting rod, a fixing plate fixedly connected to the connecting rod, a sleeve slidably connected to the outer surface of the connecting rod, a conical rim fixedly connected to the bottom of the sleeve and corresponding to the conical block, a vertical plate fixedly connected to the top of the sleeve, a first spring sleeved on the outer surface of the connecting rod, a U-shaped limiting plate fixedly connected to the fixing plate, a sliding block slidably connected inside the U-shaped limiting plate, an insertion rod fixedly connected to one side of the sliding block, and a second spring fixedly connected to the other side of the sliding block.

[0010] As a preferred technical solution of this application, a handle is fixedly connected to the top of the connecting rod, and a sliding groove is provided on the connecting rod.

[0011] As a preferred technical solution of this application, a first slider is fixedly connected to the sleeve, and the first slider corresponds to the first groove. Multiple rings are fixedly connected to the outer surface of the sleeve, and the multiple rings are evenly arranged.

[0012] As a preferred technical solution of this application, the first spring is located between the fixed plate and the sleeve, and the two ends of the first spring are fixedly connected to the fixed plate and the sleeve respectively.

[0013] As a preferred technical solution of this application, the fixing plate is provided with a through opening, and the through opening corresponds to the vertical plate, and the vertical plate is provided with a positioning hole.

[0014] As a preferred technical solution of this application, the insertion rod corresponds to the positioning hole, and the other end of the second spring is fixedly connected to the U-shaped limiting plate.

[0015] As a preferred technical solution of this application, the U-shaped limiting plate is provided with a second sliding groove on both sides, and the moving block is fixedly connected with a second slider on both sides, and the second slider corresponds to the second sliding groove.

[0016] (III) Beneficial Effects

[0017] By incorporating conical blocks, sleeves, and conical rims, the sampling device can not only handle multiple types of samples but also simultaneously sample mixed samples of different types. Furthermore, it prevents samples from getting stuck between the sleeve and conical blocks, thus ensuring a tight seal and preventing sample leakage. This expands the device's applicability, improves sampling efficiency, and enhances ease of use, thereby accelerating the sampling process. The vertical plate, insert rod, and moving block further secure the sleeve, facilitating subsequent cleaning and disinfection of the device's interior, allowing for reuse. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the overall structure of a rapid tissue sample collection device for electron microscopy.

[0019] Figure 2 A cross-sectional view of a rapid tissue sample collection device for electron microscopy;

[0020] Figure 3 This is a schematic diagram of the connecting rod in a rapid tissue sample collection device for electron microscopy.

[0021] Figure 4 This is a schematic diagram of the sleeve in a rapid tissue sample collection device for electron microscopy.

[0022] Figure 5 This is an exploded view of A in a rapid tissue sample collection device for electron microscopy.

[0023] In the picture:

[0024] 1. Connecting rod; 2. Conical block; 3. Handle; 4. Fixing plate; 5. No. 1 slide groove; 6. Sleeve; 7. Conical rim; 8. Ring; 9. Vertical plate; 10. Positioning hole; 11. No. 1 slider; 12. No. 1 spring; 13. Through port; 14. U-shaped limiting plate; 15. Moving block; 16. Insert rod; 17. No. 2 spring; 18. No. 2 slide groove; 19. No. 2 slider. Detailed Implementation

[0025] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0026] This invention provides a rapid tissue sample collection device for electron microscopy, such as... Figures 1-5 As shown, the device includes a connecting rod 1, with a conical block 2 fixedly connected to the bottom of the connecting rod 1. The top of the conical block 2 is concave downwards and is relatively sharp, allowing it to be used as a blade. A fixing plate 4 is fixedly connected to the connecting rod 1. A sleeve 6 is slidably connected to the outer surface of the connecting rod 1. The diameter of the sleeve 6 is the same as the maximum diameter of the conical block 2. A conical rim 7 is fixedly connected to the bottom of the sleeve 6, corresponding to the conical block 2. The conical rim 7 fits snugly against the inner side of the conical block 2, and its design increases the tightness between the sleeve 6 and the conical block 2, preventing liquid leakage between them. When the sample is a solid, the use of the conical rim 7 and the conical block 2 together can prevent solid from getting stuck on the top of the conical block 2, thus preventing the sleeve 6 and the conical block 2 from closing. A vertical plate 9 is fixedly connected to the top of the sleeve 6. A first spring 12 is sleeved on the outer surface of the connecting rod 1. A U-shaped limiting plate 14 is fixedly connected to the fixed plate 4. A moving block 15 is slidably connected inside the U-shaped limiting plate 14. An insertion rod 16 is fixedly connected to one side of the moving block 15. The setting of the insertion rod 16 can limit the sleeve 6, thereby facilitating the subsequent cleaning of the sampling device. A second spring 17 is fixedly connected to the other side of the moving block 15.

[0027] A handle 3 is fixedly connected to the top of the connecting rod 1. A first sliding groove 5 is provided on the connecting rod 1. The first sliding groove 5 can not only restrict the movement direction of the sleeve 6, but also limit the highest position of the sleeve 6, thereby facilitating the subsequent fixing of the sleeve 6.

[0028] A first slider 11 is fixedly connected to the sleeve 6, and the first slider 11 corresponds to the first groove 5. Multiple rings 8 are fixedly connected to the outer surface of the sleeve 6, and the multiple rings 8 are evenly arranged. The rings 8 can be used as anti-slip strips.

[0029] Spring 12 is located between the fixed plate 4 and the sleeve 6, and both ends of spring 12 are fixedly connected to the fixed plate 4 and the sleeve 6 respectively.

[0030] The fixed plate 4 is provided with a through opening 13, and the through opening 13 corresponds to the vertical plate 9. The vertical plate 9 is provided with a positioning hole 10.

[0031] The insertion rod 16 corresponds to the positioning hole 10, and the other end of the second spring 17 is fixedly connected to the U-shaped limiting plate 14.

[0032] The U-shaped limiting plate 14 is provided with a second slide groove 18 on both sides, and the moving block 15 is fixedly connected with a second slider 19 on both sides, and the second slider 19 corresponds to the second slide groove 18.

[0033] Specifically, when using the device, first insert the sampling device into the sample, then pinch the ring 8 with your fingers and pull the sleeve 6 towards the fixing plate 4. At this time, the sleeve 6 will compress the first spring 12. When the sleeve 6 moves upward, the conical block 2 will be exposed. If the sample is liquid or fine particles, the liquid or fine particles will enter the conical block 2 and also flow into the sleeve 6. If only liquid or fine particles need to be sampled, simply push the sleeve 6 back until the sleeve 6 contacts the conical block 2 and the conical edge 7 will insert into the conical block 2, thereby sealing the liquid or fine particles in the cavity formed by the sleeve 6 and the conical block 2. Then, the sampling device can be removed. When using the device, tilt it and pull the sleeve 6 upward again. At this time, the liquid or fine particles will flow out from the sampling device and fall into the petri dish for observation.

[0034] If the sample is a large solid, pull the sleeve 6 towards the fixed plate 4, then insert the conical block 2 into it and submerge it in the sample. Next, push the sleeve 6 back until it contacts the sample. At this point, pull the connecting rod 1 outward, thereby moving the conical block 2 outward. At the same time, push the sleeve 6 back again. Under the cutting action of the conical block 2 and the conical edge 7, the sample will fall into the conical block 2, thus completing the sampling. If the sample is a large mixture of solid and liquid, the same sampling method can be used, and both solid and liquid samples can be taken simultaneously.

[0035] After the sampling device is used, pull the sleeve 6 towards the fixed plate 4 and let the vertical plate 9 on the sleeve 6 pass through the opening 13. At the same time, push the moving block 15 towards the U-shaped limiting plate 14 and squeeze the second spring 17 to prevent the insertion rod 16 from blocking the vertical plate 9. When the sleeve 6 slides to the highest position, release the moving block 15. Under the elastic force of the second spring 17, the moving block 15 will move back with the insertion rod 16 until the insertion rod 16 is inserted into the positioning hole 10 on the vertical plate 9, so as to facilitate the cleaning and disinfection of the inside of the sampling device and make it reusable.

[0036] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and the inventive concept of the present utility model, should be included within the protection scope of the present utility model.

Claims

1. A rapid tissue sample collection device for electron microscopy, comprising a connecting rod (1), characterized in that: A conical block (2) is fixedly connected to the bottom of the connecting rod (1), a fixing plate (4) is fixedly connected to the connecting rod (1), a sleeve (6) is slidably connected to the outer surface of the connecting rod (1), a conical rim (7) is fixedly connected to the bottom of the sleeve (6), and the conical rim (7) corresponds to the conical block (2), a vertical plate (9) is fixedly connected to the top of the sleeve (6), a first spring (12) is sleeved on the outer surface of the connecting rod (1), a U-shaped limiting plate (14) is fixedly connected to the fixing plate (4), a sliding block (15) is slidably connected inside the U-shaped limiting plate (14), an insert rod (16) is fixedly connected to one side of the sliding block (15), and a second spring (17) is fixedly connected to the other side of the sliding block (15).

2. The rapid tissue sample collection device for electron microscopy according to claim 1, characterized in that: The top of the connecting rod (1) is fixedly connected to a handle (3), and the connecting rod (1) is provided with a first groove (5).

3. The rapid tissue sample collection device for electron microscopy according to claim 2, characterized in that: A slider (11) is fixedly connected to the sleeve (6), and the slider (11) corresponds to the groove (5). Multiple rings (8) are fixedly connected to the outer surface of the sleeve (6), and the multiple rings (8) are evenly arranged.

4. The rapid tissue sample collection device for electron microscopy according to claim 1, characterized in that: The first spring (12) is located between the fixed plate (4) and the sleeve (6), and the two ends of the first spring (12) are fixedly connected to the fixed plate (4) and the sleeve (6) respectively.

5. The rapid tissue sample collection device for electron microscopy according to claim 1, characterized in that: The fixing plate (4) is provided with a through opening (13), and the through opening (13) corresponds to the vertical plate (9). The vertical plate (9) is provided with a positioning hole (10).

6. The rapid tissue sample collection device for electron microscopy according to claim 5, characterized in that: The insertion rod (16) corresponds to the positioning hole (10), and the other end of the second spring (17) is fixedly connected to the U-shaped limiting plate (14).

7. The rapid tissue sample collection device for electron microscopy according to claim 1, characterized in that: The U-shaped limiting plate (14) is provided with a second sliding groove (18) on both sides, and the moving block (15) is fixedly connected with a second slider (19) on both sides, and the second slider (19) corresponds to the second sliding groove (18).

Images