A drug sampling structure for detecting pharmaceutical intermediates processing

Abstract

This utility model relates to the field of pharmaceutical intermediates technology, specifically a drug sampling structure for pharmaceutical intermediate processing and testing. It includes a base, a first stepper motor, a second stepper motor, and a sampling component. A vertical mounting plate is provided on the top of the base. A first stepper motor is mounted on the lower end of one side of the vertical mounting plate. The output end of the first stepper motor is connected to a first lead screw. A first lead screw block is sleeved around the first lead screw. A horizontal mounting plate is provided on one side of the vertical mounting plate. This novel pharmaceutical intermediate sampling structure has a structure that precisely controls the insertion depth, sampling speed, and time of the sampling cylinder. The collected sample can accurately represent the entire batch of pharmaceutical intermediates, which is beneficial for the processing and testing of pharmaceutical intermediates, preventing unqualified pharmaceutical intermediates from entering subsequent production stages, thereby effectively ensuring the quality and efficacy of the drugs.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical intermediates technology, specifically to a drug sampling structure for pharmaceutical intermediate processing and testing. Background Technology

[0002] Pharmaceutical intermediates are intermediate compounds used in the pharmaceutical process to synthesize drugs. They belong to fine chemical products, and their chemical structure lies between that of active pharmaceutical ingredients (APIs) and the final drug. They are synthesized through specific chemical reactions and are a key step in the construction of drug molecules. They are widely used in drug development, API synthesis, and other fields. During the processing and testing of pharmaceutical intermediates, the reaction process can be analyzed by sampling, and reaction conditions such as temperature and pH can be adjusted, thereby improving the production efficiency of pharmaceutical intermediates.

[0003] However, existing pharmaceutical intermediate sampling devices lack a structure for precise control of the insertion depth, sampling speed, and time of the sampling tube. The collected samples cannot accurately represent the entire batch of pharmaceutical intermediates, and thus unqualified pharmaceutical intermediates will enter subsequent production stages, ultimately affecting the quality and efficacy of drugs. To address this, we propose a drug sampling structure for pharmaceutical intermediate processing and testing. Utility Model Content

[0004] To address the problems in the existing technology, this utility model provides a drug sampling structure for the processing and testing of pharmaceutical intermediates. It has a structure that precisely controls the insertion depth, sampling speed and time of the sampling tube during sampling. The collected sample can accurately represent the entire batch of pharmaceutical intermediates, which is beneficial for the processing and testing of pharmaceutical intermediates and prevents unqualified pharmaceutical intermediates from entering the subsequent production process, thereby effectively ensuring the quality and efficacy of the drugs.

[0005] The technical solution adopted by this utility model to solve its technical problem is a drug sampling structure for pharmaceutical intermediate processing and testing, including a base, a first stepper motor, a second stepper motor, and a sampling component. A vertical mounting plate is provided on the top of the base. A first stepper motor is installed at the lower end of one side of the vertical mounting plate. The output end of the first stepper motor is connected to a first lead screw. A first lead screw is sleeved around the first lead screw. A horizontal mounting plate is provided on one side of the vertical mounting plate. The side of the horizontal mounting plate close to the vertical mounting plate is connected to the first lead screw. A second stepper motor is installed at the end of one side of the horizontal mounting plate. The output end of the second stepper motor is connected to a second lead screw. A second lead screw is sleeved around the second lead screw. A movable mounting plate is provided on one side of the horizontal mounting plate. The side of the movable mounting plate close to the horizontal mounting plate is connected to the second lead screw. Both the first and second stepper motors are provided with clamps. A bearing seat is provided at one end of both the vertical and horizontal mounting plates. A sampling assembly is provided on one side of the movable mounting plate. The sampling assembly includes a servo motor, a piston rod, a sampling cylinder, a sample delivery pipe, and a sample storage container. The top of the piston rod is connected to the output end of the servo motor, and the lower end of the servo motor is provided with the sampling cylinder. The lower end of the piston rod is located inside the sampling cylinder. A sample storage container is provided on one side of the sampling cylinder. A sample delivery pipe connects the sample storage container and the sampling cylinder. A piston plate is provided inside the sampling cylinder, and the bottom of the piston rod is connected to the piston plate.

[0006] By adopting the above technical solution, this novel pharmaceutical intermediate sampling structure has a structure that precisely controls the insertion depth, sampling speed and time of the sampling tube. The collected sample can accurately represent the entire batch of pharmaceutical intermediates, which is beneficial to the processing and testing of pharmaceutical intermediates and prevents unqualified pharmaceutical intermediates from entering the subsequent production process, thereby effectively ensuring the quality and efficacy of drugs.

[0007] Specifically, a first slide rail is provided on the inner side of the vertical mounting plate and on both sides of the first lead screw, and a first slider is provided on the inner side of the horizontal mounting plate and on both sides of the first lead block, with the first slider located inside the first slide rail.

[0008] Specifically, a second slide rail is provided on the inner side of the horizontal mounting plate and on both sides of the second lead screw, and a second slider is provided on the inner side of the movable mounting plate and on both sides of the second lead screw, with the second slider located inside the second slide rail.

[0009] Specifically, the sampling assembly also includes a peristaltic pump, which is located on the sample delivery pipeline.

[0010] By adopting the above technical solution, the peristaltic pump promotes sample flow by squeezing the elastic delivery tube with rotating rollers. It is suitable for sample delivery in the medical field where hygiene requirements are high and cross-contamination needs to be avoided.

[0011] Specifically, the upper and lower ends of one side of the movable mounting plate are respectively equipped with a No. 1 connecting plate and a No. 2 connecting plate via positioning plates.

[0012] By adopting the above technical solution, the servo motor is set on the top of the first connecting plate, one side of the sampling cylinder is connected to the second connecting plate, and the sample storage tank is set on the top of the second connecting plate.

[0013] Specifically, the vertical mounting plate has reinforcing plates on both sides of its bottom.

[0014] The beneficial effects of this utility model are: The present invention discloses a drug sampling structure for processing and testing pharmaceutical intermediates. A stepper motor drives a lead screw to rotate. Through the lead screw transmission, the horizontal mounting plate and the sampling component on one side of the horizontal mounting plate can move up and down reciprocally via the lead screw block, thereby achieving the purpose of adjusting the height of the sampling cylinder.

[0015] The present invention discloses a drug sampling structure for processing and testing pharmaceutical intermediates. A second stepper motor can drive a second lead screw to rotate. Through the lead screw transmission, the movable mounting plate and the sampling component on one side of the movable mounting plate can move back and forth left and right via the second lead screw block, thereby achieving the purpose of adjusting the left and right position of the sampling cylinder. Attached Figure Description

[0016] The present invention will be further described below with reference to the accompanying drawings and embodiments.

[0017] Figure 1 This is the front view of the present invention; Figure 2 This is a schematic diagram of the vertical mounting plate and the horizontal mounting plate structure of this utility model; Figure 3 This is a schematic diagram of the sampling component structure of this utility model; Figure 4 This is a schematic diagram of the piston plate structure of this utility model; Figure 5 For the present utility model Figure 2 Enlarged diagram of point A in the middle.

[0018] In the diagram: 1. Base; 2. Vertical mounting plate; 3. Stepper motor No. 1; 4. Horizontal mounting plate; 5. Sampling assembly; 501. Servo motor; 502. Piston rod; 503. Sampling cylinder; 504. Sample delivery pipeline; 505. Sample storage container; 506. Peristaltic pump; 6. Lead screw No. 1; 7. Piston plate; 8. Slide rail No. 1; 9. Slide rail No. 2; 10. Bearing seat; 11. Movable mounting plate; 12. Lead screw No. 2; 13. Stepper motor No. 2; 14. Reinforcing plate; 15. Clamp; 16. Connecting plate No. 1; 17. Positioning plate; 18. Connecting plate No. 2; 19. Slider No. 1; 20. Slider No. 2; 21. Lead block No. 1; 22. Lead block No. 2. Detailed Implementation

[0019] To make the technical means, creative features, objectives and effects of this utility model easier to understand, the present utility model will be further described below in conjunction with specific embodiments.

[0020] To precisely control the insertion depth, sampling speed, and time of the sampling tube during sampling, thereby improving sampling quality and ensuring the quality and efficacy of the medicine, such as... Figure 1-5As shown, the present invention discloses a drug sampling structure for processing and testing pharmaceutical intermediates, comprising a base 1, a first stepper motor 3, a second stepper motor 13, and a sampling assembly 5. A vertical mounting plate 2 is provided on the top of the base 1. A first stepper motor 3 is mounted on the lower end of one side of the vertical mounting plate 2. The output end of the first stepper motor 3 is connected to a first lead screw 6. A first lead screw block 21 is sleeved around the first lead screw 6. A horizontal mounting plate 4 is provided on one side of the vertical mounting plate 2. The side of the horizontal mounting plate 4 closest to the vertical mounting plate 2 is connected to the first stepper motor 5. The two steps are connected by a screw block 21. A second stepper motor 13 is installed at one end of the horizontal mounting plate 4. The output end of the second stepper motor 13 is connected to a second lead screw 12. A second screw block 22 is sleeved around the second lead screw 12. A movable mounting plate 11 is provided on one side of the horizontal mounting plate 4. The side of the movable mounting plate 11 near the horizontal mounting plate 4 is connected to the second screw block 22. A clamp 15 is provided around both the first stepper motor 3 and the second stepper motor 13. A bearing seat 10 is provided at one end of both the vertical mounting plate 2 and the horizontal mounting plate 4. A sampling assembly 5 is provided on one side of the movable mounting plate 11. The sampling assembly 5 includes a servo motor 501, a piston rod 502, a sampling cylinder 503, a sample delivery pipe 504, and a sample storage container 505. The top of the piston rod 502 is connected to the output end of the servo motor 501. The lower end of the servo motor 501 is provided with the sampling cylinder 503. The lower end of the piston rod 502 is located inside the sampling cylinder 503. A sample storage container 505 is provided on one side of the sampling cylinder 503. A sample delivery pipe 504 connects the sample storage container 505 and the sampling cylinder 503. A piston plate 7 is provided inside the sampling cylinder 503. The bottom of the piston rod 502 is connected to the piston plate 7.

[0021] In use, stepper motor 3 can drive lead screw 6 to rotate. Through lead screw transmission, horizontal mounting plate 4 and sampling component 5 on one side of horizontal mounting plate 4 can move up and down reciprocally through lead block 21, thereby achieving the purpose of adjusting the height position of sampling cylinder 503. Stepper motor 13 can drive lead screw 12 to rotate. Through lead screw transmission, movable mounting plate 11 and sampling component 5 on one side of movable mounting plate 11 can move back and forth left and right through lead screw block 22, thereby achieving the purpose of adjusting the left and right position of sampling cylinder 503. Through the transmission of servo motor 501 and piston rod 502, the position of sampling cylinder 503 can be precisely adjusted so that it reaches the predetermined sampling point. Peristaltic pump 506 can continuously and stably draw the sample inside sampling cylinder 503 and push it along sample delivery pipe 504 toward sample storage tank 505, and finally deliver the sample to sample storage tank 505 for preservation.

[0022] For example, such as Figure 1 , Figure 2 , Figure 5 As shown, a first slide rail 8 is provided on the inner side of the vertical mounting plate 2 and on both sides of the first lead screw 6, and a first slider 19 is provided on the inner side of the horizontal mounting plate 4 and on both sides of the first lead block 21. The first slider 19 is located inside the first slide rail 8.

[0023] In use, through the action of slider 19 and slide rail 8, the horizontal mounting plate 4 can slide smoothly up and down along the track of slide rail 8.

[0024] For example, such as Figure 1 , Figure 2 , Figure 5 As shown, a second slide rail 9 is provided on the inner side of the horizontal mounting plate 4 and on both sides of the second lead screw 12, and a second slider 20 is provided on the inner side of the movable mounting plate 11 and on both sides of the second lead block 22. The second slider 20 is located inside the second slide rail 9.

[0025] In use, the movable mounting plate 11 can drive the sampling component 5 to slide smoothly and steadily left and right through the action of the second slider 20 and the second slide rail 9.

[0026] For example, such as Figure 3 As shown, the sampling component 5 also includes a peristaltic pump 506, which is disposed on the sample delivery pipeline 504.

[0027] When in use, the peristaltic pump 506 promotes sample flow by squeezing the elastic delivery tube with rotating rollers. It is suitable for sample delivery in the medical field where hygiene requirements are high and cross-contamination needs to be avoided.

[0028] For example, such as Figure 3 As shown, the upper and lower ends of one side of the movable mounting plate 11 are respectively equipped with a first connecting plate 16 and a second connecting plate 18 via a positioning plate 17 and two ends.

[0029] In use, the servo motor 501 is located on the top of the first connecting plate 16, one side of the sampling cylinder 503 is connected to the second connecting plate 18, and the sample storage tank 505 is located on the top of the second connecting plate 18.

[0030] For example, such as Figure 1 As shown, reinforcing plates 14 are provided on both sides of the bottom of the vertical mounting plate 2.

[0031] When in use, the bottom of the reinforcing plate 14 is connected to the base 1, which can reinforce the vertical mounting plate 2 to enhance its stability.

[0032] In use, the servo motor 501 of the sampling component 5 is placed on the top of the first connecting plate 16, the sampling cylinder 503 is placed at one end of the second connecting plate 18, and the sample storage container 505 is placed on the top of the second connecting plate 18. The first stepper motor 3 can drive the first lead screw 6 to rotate. Through the lead screw transmission, the horizontal mounting plate 4 and the sampling component 5 on one side of the horizontal mounting plate 4 can move up and down reciprocally through the first lead block 21, thereby achieving the purpose of adjusting the height position of the sampling cylinder 503. Furthermore, if it is necessary to adjust the left and right position of the sampling cylinder 503, the second stepper motor 13 can drive the second lead screw 12 to rotate. Through the lead screw transmission, the movable mounting plate 11 and the sampling component 5 on one side of the movable mounting plate 11 can move back and forth left and right through the second lead block 22, thereby achieving the purpose of adjusting the left and right position of the sampling cylinder 503. Furthermore, after receiving the command from the control system, the servo motor 501 starts to operate. Through the transmission of the piston rod 502, the position of the sampling cylinder 503 can be precisely adjusted so that it reaches the predetermined sampling point. The servo motor 501 can drive the piston rod 502 and the piston plate 7 to suck the pharmaceutical intermediate sample into the sampling cylinder 503. The sampling cylinder 503 that has collected the sample releases the sample into the sample delivery pipe 504. Furthermore, the peristaltic pump 506 installed on the sample delivery pipe 504 starts to work. The peristaltic pump 506 creates negative pressure by alternately squeezing and releasing the elastic delivery hose through its internal rollers, continuously and stably drawing the sample inside the sampling cylinder 503 and pushing it along the sample delivery pipe 504 towards the sample storage tank 505. Under the action of the peristaltic pump 506, the sample finally flows into the sample storage tank 505 for preservation. Furthermore, there are two sets of clamps 15, which can respectively reinforce the first stepper motor 3 and the second stepper motor 13 to enhance the stability of the first stepper motor 3 and the second stepper motor 13. Furthermore, one end of the first lead screw 6 is connected to the bearing seat 10 inside the vertical mounting plate 2, and one end of the second lead screw 12 is connected to the bearing seat 10 inside the horizontal mounting plate 4. Through the bearing seat 10, both the first lead screw 6 and the second lead screw 12 can rotate smoothly when driven.

[0033] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The descriptions of the above embodiments and specifications are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of protection claimed by this utility model. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. A drug sampling structure for detecting pharmaceutical intermediates, characterized in that, The system includes a base (1), a first stepper motor (3), a second stepper motor (13), and a sampling assembly (5). A vertical mounting plate (2) is mounted on the top of the base (1). A first stepper motor (3) is mounted on the lower end of one side of the vertical mounting plate (2). The output end of the first stepper motor (3) is connected to a first lead screw (6). A first lead screw block (21) is sleeved around the first lead screw (6). A horizontal mounting plate (4) is mounted on one side of the vertical mounting plate (2). The side of the horizontal mounting plate (4) closest to the vertical mounting plate (2) is connected to the first lead screw block (21). 4) A second stepper motor (13) is installed at one end of the side. The output end of the second stepper motor (13) is connected to a second lead screw (12). A second lead screw block (22) is sleeved around the second lead screw (12). A movable mounting plate (11) is provided on one side of the horizontal mounting plate (4). The movable mounting plate (11) is connected to the second lead screw block (22) on the side close to the horizontal mounting plate (4). A clamp (15) is provided around the first stepper motor (3) and the second stepper motor (13). A bearing seat (10) is provided at one end of the vertical mounting plate (2) and the horizontal mounting plate (4). A sampling assembly (5) is provided on one side of the movable mounting plate (11). The sampling assembly (5) includes a servo motor (501), a piston rod (502), a sampling cylinder (503), a sample delivery pipe (504), and a sample storage container (505). The top of the piston rod (502) is connected to the output end of the servo motor (501). The lower end of the servo motor (501) is provided with a sampling cylinder (503). The lower end of the piston rod (502) is located inside the sampling cylinder (503). A sample storage container (505) is provided on one side of the sampling cylinder (503). A sample delivery pipe (504) is connected between the sample storage container (505) and the sampling cylinder (503). A piston plate (7) is provided inside the sampling cylinder (503). The bottom of the piston rod (502) is connected to the piston plate (7).

2. The drug sampling structure for processing and detecting pharmaceutical intermediates according to claim 1, characterized in that, A first slide rail (8) is provided on the inner side of the vertical mounting plate (2) and on both sides of the first lead screw (6). A first slider (19) is provided on the inner side of the horizontal mounting plate (4) and on both sides of the first lead block (21). The first slider (19) is located inside the first slide rail (8).

3. The drug sampling structure for processing and detecting pharmaceutical intermediates according to claim 1, characterized in that, The second slide rail (9) is provided on the inner side of the horizontal mounting plate (4) and on both sides of the second lead screw (12). The second slider (20) is provided on the inner side of the movable mounting plate (11) and on both sides of the second lead block (22). The second slider (20) is located inside the second slide rail (9).

4. The drug sampling structure for processing and detecting pharmaceutical intermediates according to claim 1, characterized in that, The sampling assembly (5) also includes a peristaltic pump (506), which is located on the sample delivery pipeline (504).

5. The drug sampling structure for detecting pharmaceutical intermediates according to claim 1, characterized in that, The upper and lower ends of one side of the movable mounting plate (11) are respectively equipped with a No. 1 connecting plate (16) and a No. 2 connecting plate (18) via a positioning plate (17) and two ends.

6. The drug sampling structure for processing and detecting pharmaceutical intermediates according to claim 1, characterized in that, The vertical mounting plate (2) has reinforcing plates (14) on both sides of its bottom.

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