Fully automated vitamin and amino acid analyzer, chromatographic column, and constant temperature oven.

Abstract

This utility model discloses a fully automatic chromatographic column constant temperature chamber for a vitamin and amino acid detector, belonging to the technical field of chromatographic detection auxiliary equipment. It solves the problems of poor insulation, unstable column fixation, and low temperature control accuracy in existing constant temperature chambers. The chamber includes an outer box, an inner box, insulation components, clamping components, and a temperature control component. The outer box is a rectangular hollow structure with a top cover. The inner box is embedded inside the outer box and houses the chromatographic column. The insulation components include side insulation plates, a bottom insulation plate, and a cover insulation plate, respectively located between the inner and outer boxes and on the inner wall of the outer cover, effectively blocking heat transfer. The clamping component consists of column clamps evenly spaced along the length of the chromatographic column, elastically clamping and fixing the column. The temperature control component includes a heating strip located between the inner box and the bottom insulation plate, a temperature sensor fixed to the cover insulation plate, and a temperature control circuit board, achieving precise temperature control. This utility model provides excellent insulation performance, reliable column fixation, and precise temperature control, offering a stable temperature environment for the chromatographic column and ensuring the separation effect and accuracy of chromatographic detection.

Description

Technical Field

[0001] This utility model relates to the field of chromatographic detection auxiliary equipment technology, specifically to a chromatographic column constant temperature oven for a fully automatic vitamin and amino acid detector. Background Technology

[0002] Chromatographic detection technology, as a core tool of modern separation science, has been widely applied in key fields such as environmental monitoring, drug development, food safety inspection, and petrochemicals due to its advantages of high separation efficiency, high sensitivity, and wide applicability.

[0003] In the complete chromatographic detection process, the chromatographic column plays a crucial role in separating the components of a mixture, and its operating status directly determines the reliability of the detection data. Temperature, as a key parameter affecting the separation efficiency of the chromatographic column, has a decisive effect on component retention time, peak shape, resolution, and detection sensitivity. For example, in the detection of pharmaceutical impurities, temperature fluctuations of ±0.5℃ can cause impurity peaks to overlap with the main peak, leading to qualitative misjudgments; in the detection of trace environmental pollutants, unstable temperature will reduce the repeatability of retention time, directly affecting the accuracy of quantitative results.

[0004] Therefore, creating a continuous and stable temperature environment for the chromatographic column is a prerequisite for ensuring the quality of chromatographic detection, and thus a dedicated chromatographic column constant temperature oven has become a core supporting equipment for chromatographic detection systems.

[0005] However, existing constant temperature chambers are insufficient to meet high-precision requirements, with prominent defects: First, the insulation structure design is simple, resulting in significant heat transfer loss between the inner and outer chambers, leading to poor temperature stability; second, the column fixing structure is not reliable enough, and is prone to loosening and displacement, affecting the detection results. For example, the slot-type design lacks buffering and is prone to shaking, causing the column bed to collapse, while the binding type has uneven force, causing the column to deform; third, the layout of the temperature control components is unreasonable, with heating elements concentrated to create a temperature gradient, and the sensor being close to the heating element rather than the column, forming a "false constant temperature".

[0006] Therefore, developing a chromatographic column constant temperature oven with excellent thermal insulation performance, reliable fixed structure, and precise temperature control can not only improve the quality and efficiency of chromatographic detection, but also meet the urgent needs of various industries for high-precision detection, and has important practical value and market significance. Summary of the Invention

[0007] To address the problems of poor insulation, unstable column fixation, and low temperature control accuracy in existing chromatographic column constant temperature ovens, this utility model provides a chromatographic column constant temperature oven with superior insulation, stable fixation, and accurate temperature control.

[0008] To solve the above problems, the present invention provides the following technical solution: A fully automated vitamin and amino acid analyzer column oven includes: The outer box is a rectangular hollow structure with an outer box cover on top; The inner box is a rectangular cavity structure with openings at both ends, which is embedded in the inner cavity of the outer box. The inner box contains a chromatographic column. The insulation component is disposed between the inner box and the outer box, and includes a side insulation panel and a bottom insulation panel; the side insulation panels are two pieces, which are respectively attached and fixed between the left and right outer walls of the inner box and the left and right inner walls of the outer box, and the bottom insulation panel is attached and fixed between the bottom outer wall of the inner box and the bottom inner wall of the outer box. The clamping assembly comprises at least two column clamps, which are fixed to the bottom inner wall of the inner box and are evenly distributed along the length of the chromatographic column for elastically clamping and fixing the chromatographic column. Temperature control components, including heating elements and temperature control circuit boards; The heating strip is located between the inner box and the bottom insulation board, and the temperature control circuit board is located on one side of the outer box and is electrically connected to the heating strip for stable temperature control inside the inner box.

[0009] The above technical solution offers the following advantages: This column oven utilizes a nested structure of an outer and inner chamber to create a stable support base. The side and bottom insulation plates between the inner and outer chambers effectively block heat transfer, significantly reducing heat loss and ensuring the stability of the inner chamber's temperature environment. At least two column clamps, evenly spaced along the column's length, on the bottom inner wall of the inner chamber provide elastic clamping to firmly secure the column, preventing loosening or shifting during use. A heating strip located between the inner chamber and the bottom insulation plate directly conducts heat to the inner chamber. Combined with a temperature control circuit board electrically connected to the outer chamber, it precisely regulates the heating strip's operation to achieve stable temperature control within the inner chamber. This synergistic effect of the above structures gives the oven excellent insulation performance, reliable column fixation, and stable temperature control, providing a suitable working temperature environment for the column and thus ensuring the separation effect and detection accuracy of chromatographic analysis.

[0010] As a further improvement to the above solution, the insulation component also includes a cover insulation plate, which is disposed on the bottom inner wall of the outer casing cover.

[0011] The above technical solution has the following benefits: by adding a heat insulation board to the cover, the top of the constant temperature chamber can be heat-insulated and sealed, preventing heat loss from the outer cover, further improving the overall heat insulation performance, and ensuring the sealing and stability of the internal temperature environment of the inner chamber.

[0012] As a further improvement to the above solution, an insulating mica sheet is also sandwiched between the heat insulation board and the outer cover.

[0013] The above technical solution has the following benefits: thermal mica sheets have both excellent thermal insulation performance and high temperature resistance, which can further enhance the thermal insulation effect of the outer cover, while also providing support and protection for the cover insulation board and extending the service life of the insulation components.

[0014] As a further improvement to the above solution, the inner ends of the outer box are respectively embedded and fixed with pipe end caps; the pipe end caps are provided with pipe channels, and the openings at both ends of the inner box are in contact with the inner end face of the pipe end caps.

[0015] The above technical solution has the following advantages: On the one hand, the tube end cap can guide and protect the chromatographic column tubing, preventing damage caused by direct friction between the tubing and the edge of the inner chamber opening; on the other hand, the fit and contact between the two ends of the inner chamber and the tube end cap can reduce the leakage of heat from the two ends of the inner chamber, while improving the installation stability of the inner chamber inside the outer chamber.

[0016] As a further improvement to the above solution, a through hole is provided on one side wall of the outer casing for the chromatographic column tubing to pass through, and the through hole is connected to the tubing channel of the tube end cap.

[0017] The above technical solution has the following advantages: the through hole and the pipeline channel through the end cap form a continuous pipeline channel, which facilitates the entry and exit of the chromatographic column into the constant temperature chamber. At the same time, it can reduce the entry of outside air into the inner chamber through pipeline gaps and reduce the impact of heat exchange on temperature stability.

[0018] As a further improvement to the above solution, the heating strip is a long strip of silicone rubber heating body, which is attached to the bottom outer wall of the inner box by high temperature resistant pressure-sensitive adhesive.

[0019] The above technical solution has the following advantages: the silicone rubber heating element has the characteristics of uniform heating, rapid temperature rise and good flexibility. When it is attached to the outer wall of the bottom of the inner box, it can achieve efficient heat conduction. Moreover, the fixing method of the high temperature pressure-sensitive adhesive is simple and reliable, which can ensure that the heating strip is not easy to fall off during long-term use.

[0020] As a further improvement to the above solution, the temperature control component also includes a temperature sensor, which is a platinum resistance sensor. It is vertically fixed to the heat insulation plate of the cover by a bracket. The temperature sensor is electrically connected to the temperature control circuit board, and its detection end faces the inner box.

[0021] The above technical solution has the following advantages: the platinum resistance sensor has the advantages of high measurement accuracy, good stability and fast response speed. Its detection end faces the inner chamber and can directly monitor the actual temperature of the environment where the chromatographic column is located, and transmit the temperature signal to the temperature control circuit board in real time. The temperature control circuit board adjusts the heating power of the heating strip according to the feedback signal to realize closed-loop control of the internal temperature of the inner chamber and effectively avoid the phenomenon of "false constant temperature".

[0022] As a further improvement to the above solution, the side insulation board and the bottom insulation board are made of insulation cotton with a thickness of 8mm, and the height of the side insulation board is consistent with the height of the inner side wall of the outer box, and the length of the bottom insulation board is adapted to the length of the inner box.

[0023] The above technical solution has the following advantages: the insulation cotton material is lightweight, has excellent insulation effect, and is low cost. The 8mm thickness can ensure the insulation performance while avoiding the overall volume of the constant temperature box being too large; the side insulation board is at the same height as the inner side wall of the outer box, and the bottom insulation board is adapted to the length of the inner box, so as to ensure that the insulation components are fully fitted with the box structure without leaving any heat dissipation gaps, thereby maximizing the insulation effect.

[0024] As a further improvement to the above solution, the bottom of the outer box cover is provided with a buckle, and the outer box cover and the outer box are detachably and sealed together by the buckle.

[0025] The above technical solution has the following advantages: the snap-on connection method is convenient to operate, and can realize the quick opening and closing of the outer box cover and the outer box, which facilitates the installation and maintenance of the chromatographic column, while ensuring the airtightness in the closed state and reducing heat loss. Attached Figure Description

[0026] To more clearly illustrate the specific embodiments of this utility model or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0027] Figure 1 This is a top view schematic diagram of the overall structure of the chromatographic column constant temperature chamber in an embodiment of this utility model.

[0028] Figure 2 This is a side cross-sectional view of the chromatographic column constant temperature oven in an embodiment of this utility model.

[0029] Figure 3 This is a schematic diagram of the cooperation structure between the outer cover and the heat insulation component in an embodiment of this utility model.

[0030] Figure 4 This is a side view schematic diagram of the mating structure between the outer casing and the pipe end cap in an embodiment of this utility model.

[0031] Figure 5 This is a schematic diagram of the chromatographic column structure in an embodiment of this utility model.

[0032] Figure 6 This is a schematic diagram of the heating strip structure in an embodiment of the present invention.

[0033] Figure 7 This is a schematic diagram of the electrical principle of the temperature control circuit board, heating strip, and temperature sensor in an embodiment of this utility model.

[0034] In the diagram: 1-Outer box; 11-Outer box cover; 111-Snap fastener; 12-Pipe end cap; 13-Through hole; 2-Inner box; 3-Chromatographic column; 31-Side insulation plate; 32-Bottom insulation plate; 33-Lid insulation plate; 34-Insulating mica sheet; 41-Column clamp; 51-Heating strip; 52-Temperature sensor. Detailed Implementation

[0035] The embodiments of this utility model are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain this utility model, and should not be construed as limiting this utility model.

[0036] In the description of this utility model, it should be understood that the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc., indicating the orientation or positional relationship are based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this utility model and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0037] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this utility model, "a plurality of" means two or more, unless otherwise explicitly specified.

[0038] In this utility model, unless otherwise explicitly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0039] In this utility model, unless otherwise explicitly specified and limited, "above" or "below" the second feature can mean that the first feature is in direct contact with the second feature, or that the first feature is in indirect contact with the second feature through an intermediate medium. Furthermore, "above," "on top of," and "over" the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature. Example 1

[0040] like Figures 1 to 6 As shown, a fully automated vitamin and amino acid analyzer column oven includes: Outer box 1, the outer box 1 is a rectangular hollow aluminum profile, and its top is equipped with an outer box cover 11; The inner box 2 is an industrial U-shaped aluminum profile with a rectangular cavity structure open at both ends. It is embedded in the inner cavity of the outer box 1. The inner box 2 is equipped with a chromatographic column 3. The insulation component is located between the inner box 2 and the outer box 1, and includes a side insulation panel 31 and a bottom insulation panel 32. The side insulation panel 31 consists of two pieces, which are respectively attached and fixed between the left and right outer walls of the inner box 2 and the left and right inner walls of the outer box 1. The bottom insulation panel 32 is attached and fixed between the bottom outer wall of the inner box 2 and the bottom inner wall of the outer box 1. The clamping assembly consists of two column clamps 41, which are fixed to the bottom inner wall of the inner box 2 by internal hexagonal bolts and are evenly distributed along the length of the chromatographic column 3 for elastically clamping and fixing the chromatographic column 3. The temperature control component includes a heating strip 51 and a temperature control circuit board. The heating strip 51 is located between the inner box 2 and the bottom insulation plate 32. The temperature control circuit board is located on one side of the outer box 1 and is electrically connected to the heating strip 51 for stable temperature control inside the inner box 2.

[0041] In this embodiment, the insulation component also includes a cover insulation plate 33, which is disposed on the bottom inner wall of the outer box cover 11. By adding the cover insulation plate 33, the top of the constant temperature box can be insulated and sealed to prevent heat loss from the outer box cover 11, further improving the overall insulation performance and ensuring the sealing and stability of the internal temperature environment of the inner box 2.

[0042] In this embodiment, an insulating mica sheet 34 is also sandwiched between the cover insulation plate 33 and the outer cover 11. The insulating mica sheet 34 has both excellent heat insulation performance and high temperature resistance, which can further enhance the heat insulation effect at the outer cover 11, and at the same time can support and protect the cover insulation plate 33, extending the service life of the insulation components.

[0043] In this embodiment, the inner two ends of the outer box 1 are respectively embedded and fixed with tube end caps 12; the tube end caps 12 are provided with a pipeline channel, and the openings at both ends of the inner box 2 are in contact with the inner end face of the tube end caps 12; the setting of the tube end caps 12 can guide and protect the pipeline of the chromatographic column 3, and avoid damage caused by direct friction between the pipeline and the edge of the opening of the inner box 2; on the other hand, the contact between the two ends of the inner box 2 and the tube end caps 12 can reduce the leakage of heat from the openings at both ends of the inner box 2, and at the same time improve the installation stability of the inner box 2 inside the outer box 1.

[0044] In this embodiment, a through hole 13 is provided on one side wall of the outer box 1 for the chromatographic column 3 pipeline to pass through, and the through hole 13 is correspondingly connected to the pipeline channel of the tube end cap 12; the through hole 13 and the pipeline channel of the tube end cap 12 form a continuous pipeline channel, which facilitates the entry and exit of the chromatographic column 3 pipeline into the constant temperature chamber, and at the same time reduces the entry of outside air into the inner box 2 through pipeline gaps, thereby reducing the impact of heat exchange on temperature stability.

[0045] In this embodiment, the heating strip 51 is a long strip of silicone rubber heating body, which is attached to the bottom outer wall of the inner box 2 by high temperature resistant pressure-sensitive adhesive. The silicone rubber heating body has the characteristics of uniform heating, rapid temperature rise and good flexibility. It can achieve efficient heat conduction when attached to the bottom outer wall of the inner box 2. Moreover, the fixing method of the high temperature resistant pressure-sensitive adhesive is simple and reliable, which can ensure that the heating strip 51 is not easy to fall off during long-term use.

[0046] In this embodiment, the temperature control component also includes a temperature sensor 52, which is a platinum resistance sensor. It is vertically fixed on the cover insulation plate 33 by a bracket. The temperature sensor 52 is electrically connected to the temperature control circuit board, and its detection end faces the inner chamber 2. The platinum resistance sensor has the advantages of high measurement accuracy, good stability and fast response speed. Its detection end facing the inner chamber 2 can directly monitor the actual temperature of the environment where the chromatographic column 3 is located and transmit the temperature signal to the temperature control circuit board in real time. The temperature control circuit board accurately adjusts the heating power of the heating strip 51 according to the feedback signal to realize closed-loop control of the internal temperature of the inner chamber 2 and effectively avoid the phenomenon of "false constant temperature".

[0047] In this embodiment, the side insulation panel 31 and the bottom insulation panel 32 are made of insulation cotton with a thickness of 8mm. The height of the side insulation panel 31 is consistent with the height of the inner wall of the outer box 1, and the length of the bottom insulation panel 32 is adapted to the length of the inner box 2. The insulation cotton material is lightweight, has excellent insulation effect, and is inexpensive. The 8mm thickness can ensure the insulation performance while avoiding the overall volume of the constant temperature box being too large. The fact that the side insulation panel 31 is consistent with the height of the inner wall of the outer box 1 and the bottom insulation panel 32 is adapted to the length of the inner box 2 can ensure that the insulation components are fully fitted with the box structure without leaving any heat dissipation gaps, thereby maximizing the insulation effect.

[0048] In this embodiment, the bottom of the outer cover 11 is provided with a buckle 111, and the outer cover 11 and the outer box 1 are detachably and sealed by the buckle; the buckle connection method is convenient to operate, so as to ensure the quick opening and closing of the outer cover 11 and the outer box 1, which facilitates the installation and maintenance of the chromatographic column 3, while ensuring the sealing performance in the closed state and reducing heat loss.

[0049] In this embodiment, a rubber sealing ring is provided on the inner wall of the through hole 13 to enhance the sealing performance after the pipeline is installed.

[0050] In this embodiment, the column clamp 41 is made of elastic stainless steel.

[0051] In this embodiment, no specific algorithm is involved between the temperature control circuit board, the heating strip 51, and the temperature sensor 52. This part is conventional technology in the field and will not be described in detail.

[0052] Basic working principle: This column oven achieves precise temperature control of the environment surrounding the chromatographic column through a synergistic design of "insulated sealing structure + closed-loop temperature control system". The core working principle is as follows: Thermal insulation environment construction: A double-cavity structure with an outer and inner box is adopted. The side and bottom insulation boards are fixed between the cavities. The inner side of the outer box cover is equipped with a cover insulation board and insulation mica sheet. At the same time, through the design of fitting the pipe end cap with the two ends of the inner box, setting the rubber sealing ring on the inner wall of the through hole, and the outer box cover and outer box with fastener sealing connection, a full-dimensional sealed thermal insulation space is formed, which minimizes the heat loss of the inner box to the outside and lays the foundation for constant temperature control. Stable installation of the chromatographic column: The chromatographic column is elastically clamped and fixed at equal intervals along the length of the column by the elastic stainless steel column clamp at the bottom of the inner chamber, ensuring the stability of the column position in a constant temperature environment; the tube end cap and the through hole form a continuous pipeline channel, which not only achieves safe guidance of the chromatographic column pipeline, but also avoids friction damage between the pipeline and the edge of the chamber. Closed-loop constant temperature control: Heating module: It adopts a long strip of silicone rubber heating element, which is attached to the outer wall of the bottom of the inner box with high temperature resistant pressure-sensitive adhesive. It utilizes its uniform heating and rapid heating characteristics to efficiently transfer heat to the inner box. Temperature monitoring: The platinum resistance temperature sensor is vertically fixed to the heat insulation plate of the cover, with the detection end facing directly towards the inner chamber. It collects the actual temperature signal of the environment where the chromatographic column is located in real time and transmits it to the temperature control circuit board. Precise adjustment: The temperature control circuit board receives feedback signals from the temperature sensor and adjusts the heating power of the heating strip through closed-loop control logic. When the inner chamber temperature reaches the set value, the heating power is reduced, and when the temperature is lower than the set value, the heating power is increased, effectively avoiding "false constant temperature" and ensuring that the internal temperature of the inner chamber is stable within the target range.

[0053] In summary, this constant temperature chamber reduces heat loss through a sealed and insulated structure, and combined with a closed-loop temperature control mechanism of "heating-detection-adjustment" provides a stable and uniform constant temperature working environment for the chromatographic column, while also taking into account the convenience of installation and maintenance. Example 2

[0054] like Figure 7 As shown, in a further improvement to Embodiment 1 above, the temperature control circuit of this column oven includes a control unit (integrated on a temperature control circuit board), a 24V DC power supply, an NTC90,1M temperature sensor, and a 24V 12W heating silica gel sheet. The specific connection relationships of each component are as follows; The control unit is equipped with 6 terminal blocks, namely terminals 1, 2, 3, 4, and 5, including one multiplexed terminal 1. Terminal 2 corresponds to the "stop" function interface, and terminal 5 corresponds to the "start" function interface.

[0055] 24V DC power supply wiring connection: 24V DC positive line: One end is connected to terminal 1 on the top of the control unit, and the other end is directly led out and connected to one of the terminals of the heating silicone pad; 24V DC negative line: One end is connected to terminal 2 (“stop” interface) of the control unit, and the other end leads out a branch line for connecting the NTC90,1M temperature sensor.

[0056] The two terminals of the NTC90,1M temperature sensor (non-polarized) are connected to: One end: Connect to the branch end of the 24V DC negative line; The other end: connects to terminal 3 of the control unit.

[0057] Connect the two terminals of the 24V 12W heating silicone pad to: One end: Connect to the 24V DC positive line (from terminal 1 on the top of the control unit); The other end: connects to the lower terminal 1 of the control unit (which is the same functional terminal of the control unit as the upper terminal 1, to close the power supply circuit).

[0058] The internal logic circuit of the control unit connects terminal 4 and terminal 5 ("start" interface) through an internal preset circuit to trigger the start logic of the heating circuit.

[0059] The basic working principle of constant temperature: 1. Temperature Acquisition: Real-time temperature monitoring using an NTC temperature sensor. The NTC90,1M temperature sensor (non-polarized) is installed in the inner enclosure area, and its resistance value exhibits a negative correlation with temperature changes. The sensor is connected to terminal 3 of the control unit via a 24V DC negative line to collect the temperature of the inner chamber in real time, and converts the temperature signal into a resistance signal and transmits it to the control unit. 2. Signal Processing: Temperature Comparison and Logic Judgment in the Control Unit The control unit (integrated into the temperature control circuit board) is the core of the constant temperature control, and its working logic is as follows: It receives the real-time temperature electrical signal transmitted by the NTC sensor and converts it into the "actual temperature value"; It compares the actual temperature with the user's preset "target temperature value" (e.g., 40℃) in real time to determine the temperature deviation status (actual temperature < target temperature / close to target temperature / ≥ target temperature). 3. Heating Adjustment: Dynamic power control of the heating silicone sheet. The control unit outputs different control signals through terminal 1 (heating circuit interface) according to the temperature deviation to adjust the working status of the 24V 12W heating silicone pad. When the actual temperature is less than the target temperature (deviation > 0.2℃): the control unit outputs a full power supply signal, and the heating silicone pad heats up at a rated power of 12W to quickly increase the temperature of the inner chamber; When the actual temperature is close to the target temperature (deviation ≤ 0.2℃): the control unit uses PWM pulse width modulation technology to adjust the "duty cycle" of the output signal (e.g., from 100% to 30%), reducing the actual heating power of the heating silicone sheet and avoiding temperature overshoot; When the actual temperature is greater than or equal to the target temperature: the control unit cuts off the power supply to terminal 1, and the heating silicone sheet stops heating; 4. Closed-loop feedback: Dynamic maintenance of constant temperature. The entire system is a negative feedback closed-loop control system. When the temperature inside the chamber drops back to the "target temperature - 0.1℃" due to slight heat loss, the NTC sensor transmits the temperature drop signal to the control unit. The control unit restarts the heating silicone pad (low power mode) to replenish the heat of the inner chamber and raise the temperature back to the target value; Repeat the cycle of "temperature acquisition → comparison and judgment → heating adjustment" to eventually stabilize the inner chamber temperature within the range of "target temperature ± 0.2℃" to achieve the constant temperature environment required by the chromatographic column.

[0060] In this embodiment, the determination of temperature deviation does not involve a specific algorithm, as this is a conventional technique in the art and will not be described in detail.

[0061] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this utility model, and are not intended to limit it. Although the utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this utility model.

Claims

1. A fully automated vitamin and amino acid analyzer column constant temperature oven, characterized in that, include: The outer box (1) is a rectangular cavity structure with an outer box cover (11) on its top. The inner box (2) is a rectangular cavity structure with openings at both ends. It is embedded in the inner cavity of the outer box (1). The inner box (2) is equipped with a chromatographic column (3). The insulation component is located between the inner box (2) and the outer box (1), and includes a side insulation panel (31) and a bottom insulation panel (32). The side insulation panel (31) consists of two pieces, which are respectively attached and fixed between the left and right outer walls of the inner box (2) and the left and right inner walls of the outer box (1). The bottom insulation panel (32) is attached and fixed between the bottom outer wall of the inner box (2) and the bottom inner wall of the outer box (1). The clamping assembly consists of at least two column clamps (41), which are fixed to the bottom inner wall of the inner box (2) and are evenly distributed along the length of the chromatographic column (3) for elastically clamping and fixing the chromatographic column (3). Temperature control components, including heating strip (51) and temperature control circuit board; The heating strip (51) is located between the inner box (2) and the bottom insulation board (32). The temperature control circuit board is located on one side of the outer box (1) and is electrically connected to the heating strip (51) for stable temperature control inside the inner box (2).

2. The chromatographic column constant temperature oven for a fully automatic vitamin and amino acid detector according to claim 1, characterized in that, The insulation component also includes a cover insulation plate (33), which is located on the bottom inner wall of the outer cover (11).

3. The chromatographic column constant temperature oven for a fully automatic vitamin and amino acid detector according to claim 2, characterized in that, Insulating mica sheet (34) is also sandwiched between the heat insulation board (33) and the outer cover (11).

4. The chromatographic column constant temperature oven for a fully automatic vitamin and amino acid detector according to claim 1, characterized in that, The outer box (1) has pipe end caps (12) embedded and fixed at both ends; the pipe end caps (12) have pipe channels running through them, and the openings at both ends of the inner box (2) are in contact with the inner end face of the pipe end caps (12).

5. The chromatographic column constant temperature oven for a fully automatic vitamin and amino acid detector according to claim 4, characterized in that, The outer casing (1) has a through hole (13) on one side wall for the chromatographic column (3) to pass through, and the through hole (13) is connected to the pipeline channel of the pipe end cap (12).

6. The chromatographic column constant temperature oven for a fully automatic vitamin and amino acid detector according to claim 1, characterized in that, The heating strip (51) is a long strip of silicone rubber heating body, which is attached to the bottom outer wall of the inner box (2) by high temperature pressure-sensitive adhesive.

7. The chromatographic column constant temperature oven for a fully automatic vitamin and amino acid detector according to claim 1, characterized in that, The temperature control component also includes a temperature sensor (52), which is a platinum resistance sensor. It is vertically fixed on the cover insulation plate (33) by a bracket. The temperature sensor (52) is electrically connected to the temperature control circuit board, and its detection end faces the inner box (2).

8. The chromatographic column constant temperature oven for a fully automatic vitamin and amino acid detector according to claim 1, characterized in that, The side insulation board (31) and bottom insulation board (32) are made of insulation cotton with a thickness of 8mm. The height of the side insulation board (31) is consistent with the height of the inner wall of the outer box (1), and the length of the bottom insulation board (32) is adapted to the length of the inner box (2).

9. The chromatographic column constant temperature oven for a fully automatic vitamin and amino acid detector according to claim 1, characterized in that, The bottom of the outer box cover (11) is provided with a buckle (111), and the outer box cover (11) and the outer box (1) are detachably and sealed together by the buckle (111).

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