Stereoisomers of 10,11-difluoro-12-((2-fluoro-4-iodophenyl)amino)-5,6-dihydroxy-4,5,6,7-tetrahydro-1h-spiro[benzo[b][1,5,4]oxatiazecina-3,1'-cyclopropane] 2,2-dioxide, and compositions comprising and methods of use thereof
CO20260010827A2Pending Publication Date: 2026-08-20PASITHEA THERAPEUTICS CORP
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Patent Information
- Application Number
- CO20260010827
- Authority / Receiving Office
- CO · CO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2025-01-02
- Filing Date
- 2026-07-29
- Publication Date
- 2026-08-20
Abstract
This paper describes stereoisomeric compounds of 10,11-difluoro-12-((2-fluoro-4-iodophenyl)amino)-5,6-dihydroxy-4,5,6,7-tetrahydro-1H-spiro[benzo[b][1,5,4]oxatiazecina-3,1'-cyclopropane] 2,2-dioxide and pharmaceutical compositions thereof. Methods for their use in treating, preventing, or improving diseases or disorders in which the RAS pathway is upregulated, such as cancer, RASopathies, and laminopathies, are also provided.
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