CD8-binding cytokine linkers and methods of using them
CO20260012441A2Pending Publication Date: 2026-09-28ASTRAZENECA AB
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Patent Information
- Application Number
- CO20260012441
- Authority / Receiving Office
- CO · CO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2025-01-31
- Filing Date
- 2026-08-26
- Publication Date
- 2026-09-28
Abstract
The description provides a cytokine linker comprising an antibody that specifically binds to human CD8, and wherein the antibody is fused to a cytokine (e.g., IL-2). Compositions and methods of delivery of the compositions for preferentially expanding T cells and treating cancer are also provided.
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