α7β1 integrin antibodies and their uses
CO20260013201A2Pending Publication Date: 2026-09-28MORPHIC THERAPEUTIC INC
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Patent Information
- Application Number
- CO20260013201
- Authority / Receiving Office
- CO · CO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2025-03-14
- Filing Date
- 2026-09-11
- Publication Date
- 2026-09-28
Abstract
This description provides, among other things, a class of antibodies or an antigen-binding fragment that bind to the calf-1 or calf-2 domain of the α7β1 integrin. The anti-α7β1 antibodies of this description are effective in stabilizing the α7β1 integrin in the extended-closed and extended-open conformations, thereby enhancing binding to laminins.
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