Viral vector and producer cell

Abstract

There is provided a viral vector having a lipid bilayer envelope comprising an antibody binding domain displayed on the exterior of the envelope that is cell-type specific; a viral envelope protein displayed on the exterior of the envelope that is able to facilitate infection of the same cell type; and a nucleic acid molecule comprising a promoter expressible in the same cell type. Further provided are methods of making the viral vector and methods of using the viral vector to modify cells and treat diseases / conditions.