DEMINERALIZED BONE FIBER IMPLANT COMPOSITIONS AND THEIR MANUFACTURING METHODS
Patent Information
- Application Number
- DE602020049119
- Authority / Receiving Office
- DE · DE
- Patent Type
- Patents
- Current Assignee / Owner
- Priority Date
- 2019-09-18
- Filing Date
- 2020-02-07
- Publication Date
- 2025-04-09
- Estimated Expiration
- 2040-02-07
AI Technical Summary
Current surgical techniques face challenges in achieving and maintaining fixation in osteoporotic vertebrae, leading to issues like screw loosening and failure, especially in patients with compromised bone strength due to conditions like osteoporosis or renal osteodystrophy.
The use of a composition comprising a plurality of demineralized bone fibers formed into specific shapes, such as a truncated cone with a flared end, to enhance screw fixation and tissue integration with bone. These fiber implants are placed in the bone hole before screw insertion, providing a denser substrate for screw engagement and promoting local bone growth.
The demineralized bone fiber implants increase the insertion torque and pull-out force of screws, reducing the likelihood of screw dislodgement and enhancing long-term bone repair, particularly in osteoporotic bone. Additionally, their osteoinductive and osteoconductive properties stimulate local bone growth.