Methods for disinfecting and sterilizing organic material
Patent Information
- Authority / Receiving Office
- DE · DE
- Patent Type
- Applications
- Current Assignee / Owner
- Filing Date
- 1944-03-28
- Publication Date
- 1952-08-04
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
Existing methods for sterilizing sensitive organic substances using alcoholic iodine methyl vapors at negative pressure require complex equipment and prolonged incubation times, making them inefficient and difficult to monitor.
A method utilizing a mixture of alcohol and methyl iodide vapors at superatmospheric pressure in a closed system for sterilization, ensuring complete penetration and reducing sterilization time using simple apparatus.
The method achieves perfect sterilization of organic materials with reduced time and simplified equipment by using overpressure to enhance vapor penetration.
Description
[0001] Method for disinfecting and sterilizing organic material The present invention relates to a method for disinfecting and Disinfection of objects, characterized in that the goods are treated with vapors of a mixture of methyl iodide and alcohol or is treated with another water-miscible solvent at temperatures between about 35 and 70°C, preferably between 45 and 6°C. According to a preferred embodiment, the treatment is not carried out at atmospheric pressure, but rather at overpressure, i.e., in a closed system. System executed.
[0002] It is known that sensitive organic substances such as nvie katgut can be disinfected with alcoholic iodide yl vapors under negative pressure. Maintaining a specific vacuum during sterilization requires a complex apparatus, the monitoring of which is particularly careful. A complete disinfection process must be achieved. In contrast, the present invention relates to a method for disinfection. and disinfection, which is characterized by the fact that it can be carried out with simple apparatus. According to the preferred embodiment, The disinfection or sterilization process occurs under overpressure, i.e., under the overpressure that arises in the closed system due to the The temperature is set between 45 and 7°C by the mixture of alcohol and methyl iodide. This method is particularly advantageous because, as a result of the Overpressure the methyl iodide-"", alcohol- The vapors completely penetrate the items being sterilized, ensuring perfect sterilization and significantly reducing the sterilization time.
[0003] Instead of alcohol, any other water-miscible organic solvent, such as acetone, can be used. It is advantageous if the diluent contains a few percent water.
[0004] Example 1: Horsehair, which in all samples examined contained numerous anthrax bacteria or spores alongside other saprophytes The samples were exposed to a methyl iodide alcohol vapor at 56°. The vapor was developed from a liquid consisting of 95 g of 96% alcohol. The mixture consisted of ethyl alcohol and 5 g of methyl iodoca. The test durations were 6 and 24 hours. In test A, the experiment was carried out at normal pressure. while the material in experiment B was treated under overpressure, i.e., at the pressure that occurs at the applied temperature of 56°C. The incubation period was 10 days. To precisely verify that all anthrax bacilli present had been destroyed, 0.5 cc of white bouillon was added. Mice were injected subcutaneously. In the presence of anthrax bacilli, the mice died within 24 hours. The detection of these germs The sample was then examined microscopically in the smeared heart blood. AWAY 6 hours + 24 hours + = Anthrax was still present.
Claims
[0005] PATENT CLAIMS: i. Method for disinfecting and sterilizing organic material, characterized in that the material is treated with the Vaporizing a mixture of methyl iodide and alcohol or another water-miscible solvent at temperatures between approximately 35 and 70', expediently between 45 and 60', is treated.
2. Method according to claim 1, characterized in that the material is treated under overpressure, i.e., li. in a closed system. Referenced publications: Swiss patent no. 216 547; "Zeitschrift für Chirurgie" 86, (igo6), p. 170-
Citation Information
Patent Citations
Method and device for sterilizing surgical sutures.
CH216547A