Early detection and monitoring of neurodegenerative diseases using a multi-disease diagnostic platform

EP4562427A4Pending Publication Date: 2026-07-15DURIN LIFE SCIENCES INC

Patent Information

Authority / Receiving Office
EP · EP
Patent Type
Applications
Current Assignee / Owner
DURIN LIFE SCIENCES INC
Filing Date
2023-07-27
Publication Date
2026-07-15

AI Technical Summary

Technical Problem

Current methods for diagnosing neurodegenerative diseases like Alzheimer's and Parkinson's are invasive, expensive, and lack accuracy for early-stage detection, making it difficult to initiate timely treatment and monitor disease progression effectively.

Method used

A multi-disease diagnostic platform using a protein target set that forms immunocomplexes with specific autoantibody biomarkers in biological samples, combined with a classification algorithm, to detect and quantify AD- and PD-related autoantibodies in blood samples, enabling early-stage diagnosis and monitoring.

Benefits of technology

The platform achieves high accuracy in detecting early-stage neurodegenerative diseases, with a detection accuracy of at least 75% for AD and 87.9% for PD, allowing for early intervention and monitoring of disease progression.

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Abstract

Methods, systems and kits useful for the detection and diagnosis of neurodegenerative diseases including Alzheimer's Disease (AD)- and early-stage Parkinson's Disease-related pathology, and methods of preparing labeled immunocomplexes useful for detecting AD- and PD-related pathology are provided.
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