Transgenic plants containing artificial mirtrons

Abstract

The present application relates to a transgenic plant comprising an integrated host gene capable of being expressed in the plant, the host gene comprising an artificial mirtron capable of silencing a target gene and having a sequence comprising a 5' donor splice site, a branch point, a polypyrimidine tract, a 3' acceptor splice site, and a guide sequence complementary to a target sequence in the target gene, to methods of preparation thereof, and to nucleic acids comprising such artificial mirtrons.

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