Cas polypeptides with altered pam recognition

EP4684008A1Pending Publication Date: 2026-01-28PIONEER HI BREED INTERNATIONAL INC

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Patent Information

Application Number: EP2024721269
Authority / Receiving Office: EP · EP
Patent Type: Applications
Current Assignee / Owner
Priority Date: 2023-09-27
Filing Date: 2024-03-19
Publication Date: 2026-01-28

Application Information

Patent Timeline

27 Sep 2023

Priority

19 Mar 2024

Application

EP2024721269

28 Jan 2026

Publication

EP4684008A1

IPC: C12N9/22

CPC: C07K2319/80; C07K2319/00; C12N9/22; C12N9/222; C12N9/78; C12N9/1276; C12N2310/20

Inventors: YOUNG, JOSHUA K.

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Abstract

The present disclosure relates to methods for altering the PAM specificity of Cas-alpha polypeptides. The disclosure also relates to Cas-alpha 10 polypeptides having altered PAM specificity and methods and compositions for use thereof.

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