Methods for treating polyq disease and novel adipose tissue derived mesenchymal stem cells

EP4712989A1Pending Publication Date: 2026-03-25STEMINENT BIOTHERAPEUTICS
View PDF 0 Cites 0 Cited by

Patent Information

Authority / Receiving Office
EP · EP
Patent Type
Applications
Current Assignee / Owner
Filing Date
2024-05-15
Publication Date
2026-03-25

Smart Images

  • Figure PCTCN2024093397-FTAPPB-I100001
    Figure PCTCN2024093397-FTAPPB-I100001
  • Figure PCTCN2024093397-FTAPPB-I100002
    Figure PCTCN2024093397-FTAPPB-I100002
  • Figure 00000015_0000
    Figure 00000015_0000
Patent Text Reader

Abstract

Provided is the use of adipose tissue derived stem cells that express Activin A or the combination of Activin A and modified adipose tissue derived stem cells, for treating polyQ diseases, such as spinocerebellar ataxia 3 (SCA 3), by reducing a misfolded and aggregated polyQ protein, such as ataxin-3 protein. Also provided is a composition for reducing misfolded and aggregated polyQ proteins, wherein the composition comprises a population of modified adipose tissue derived stem cells and Activin A.
Need to check novelty before this filing date? Find Prior Art