Methods of treating blood disorders with vwf-targeted monospecific antibodies

EP4762096A1Pending Publication Date: 2026-06-24HEMAB APS

Patent Information

Authority / Receiving Office
EP · EP
Patent Type
Applications
Current Assignee / Owner
HEMAB APS
Filing Date
2024-08-16
Publication Date
2026-06-24

AI Technical Summary

Technical Problem

Current treatments for blood disorders related to von Willebrand factor (VWF) are inadequate in effectively managing the condition.

Method used

Development of monospecific antibodies specifically designed to target the VWF protein, leading to its accumulation in blood plasma.

Benefits of technology

The antibodies effectively accumulate VWF in blood plasma, potentially improving treatment outcomes for blood disorders associated with VWF.

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Abstract

Provided herein are antibodies, compositions, and methods of use thereof. The disclosed antibodies bind to von Willebrand factor in blood plasma of a subject. Such antibodies are useful for methods of treatment, such methods of treating one or more blood disorders characterized by excessive bleeding.
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