Composition with polar and non-polar phase

Abstract

The invention relates to a composition, wherein the composition comprises a polar phase and a non-polar phase, wherein the composition contains a lipophilic extract of ginger (Zingiber officinale) and at least one further lipophilic ingredient, the polar phase contains, based on the total weight of the polar phase, at least 20 wt.% polyol, at least 3 wt.% and less than 20 wt.% water and at least one hydrophilic ingredient, and the composition contains, per 100 g of the composition, 0.5 g to 10 g lecithin.

Description

[0001] COMPOSITION WITH POLAR AND NON-POLAR PHASE

[0002] Description

[0003] The invention relates to a composition comprising a polar phase and a non-polar phase.

[0004] Two-phase systems, i.e. systems with a polar phase and a non-polar phase, represent an important dosage form, e.g. for food supplements or cosmetic preparations.

[0005] WO 2019 / 233552 A1 describes the need to provide two-phase systems that are droppable and transparent and exhibit good physical, chemical, and microbiological stability despite the use of naturally occurring ingredients. Emulsions are also described, i.e., complex two-phase systems consisting of two immiscible phases, with an inner phase stably distributed in the form of drops within an outer phase. Three types of stability determine the long-term quality and storage properties of emulsions and similar two-phase systems: physical stability, chemical stability, and microbiological stability.

[0006] Physical stability describes the ability of a two-phase system to maintain the fine and uniform distribution of the dispersed phase over an extended period of time, achieved during emulsification by mechanical forces. This stability can be improved, for example, by using surfactants or emulsifiers, by equalizing the density of the two phases, or by increasing the viscosity of the outer phase using so-called quasi-emulsifiers. Surfactants are divided into anionic, cationic, amphoteric, and non-ionic surfactants. Non-ionic surfactants offer several advantages: They do not form ions in aqueous solutions, are neutral in reaction, are not affected by electrolytes, and are less susceptible to chemical influences. Transparent or at least translucent two-phase systems are particularly desirable in the dietary and cosmetic sectors.In some cases, this can be achieved by an inner phase with droplet sizes in the nanometer range. Such droplet sizes are achieved, for example, by micelles, the formation of which can be mediated by an emulsifier and a co-emulsifier. Ethoxylated surfactants or synthetic surfactants with a high HLB value are often used as emulsifiers, and alcohols as co-emulsifiers. Emulsifying oils often requires a significant amount of emulsifier and co-emulsifier. However, synthetic emulsifiers are rejected by some members of the population. Furthermore, alcohols such as ethanol and propanol are cytotoxic and must be avoided, especially in oral preparations for children, alcoholics, pregnant women, etc.

[0007] In addition to the physical stability of a two-phase system, chemical and microbiological stability must also be ensured. Chemical stability is particularly problematic in two-phase systems because autoxidation and hydrolytic processes in oils and fats are favored in the presence of water. Furthermore, air, and thus oxygen, are often incorporated during the production of two-phase systems, which also promotes oxidation. This is problematic because, for example, oxidized fatty acids are not only no longer available for physiological purposes, but harmful products are formed during oxidation. In practice, the incorporation of hydrophilic ingredients into two-phase systems alongside solvents is generally avoided, as this often further negatively impacts chemical stability.

[0008] Two-phase systems, as water-containing systems, provide good breeding grounds for microorganisms. Therefore, preservatives are usually added to such two-phase systems. However, the surfactants required for physical stability can impair the effectiveness of the preservatives. Preservatives also partially migrate into the lipophilic phase. To ensure the concentration of preservative in the aqueous phase is sufficiently high to effect preservation, such two-phase systems contain a relatively high preservative content. However, certain preservatives, such as p-hydroxybenzoic acid esters, can cause intolerances and allergies.

[0009] Many people desire products based on compatible and naturally occurring ingredients or excipients, although this is often technically difficult to achieve. Two-phase systems such as emulsions, in particular, represent complex systems in which ingredients cannot be mixed arbitrarily. Instead, a mixture must be developed that meets the user's needs and the high technical requirements for physical, chemical, and microbiological stability.

[0010] The present invention is based on the object of providing a further improved two-phase system that enables improved nutrient transport. At the same time, the two-phase system should be as digestible as possible, non-allergenic, and psychologically and physiologically positively received by humans. The two-phase system should not contain monohydric alcohols, in particular ethanol or propanol. Furthermore, the two-phase system should be physically, chemically, and microbiologically stable, while using only naturally occurring ingredients and excipients wherever possible. Synthetic emulsifiers and preservatives should be avoided.

[0011] According to the invention, this object is achieved by a composition according to claim 1.

[0012] The invention is based on the idea of ​​specifying a composition, wherein the composition comprises a polar phase and a non-polar phase, wherein the composition contains a lipophilic extract of ginger (Zingiber officinale) and at least one further lipophilic ingredient, the polar phase contains, based on the total weight of the polar phase, at least 20 wt.% polyol, at least 3 wt.% and less than 20 wt.% water and a hydrophilic ingredient, and the composition contains 0.5 g to 10 g of lecithin per 100 g of the composition. In addition to the lecithin and the lipophilic extract of ginger and in addition to the water and polyol in the polar phase, the composition contains at least one hydrophilic (synonym: polar) ingredient in the polar phase and at least one further lipophilic (synonym: non-polar) ingredient in the non-polar (synonym: lipophilic) phase.The composition enables the simultaneous application of hydrophilic and hydrophobic ingredients in a stable dosage form, and these ingredients are absorbed particularly efficiently by the human body. Due to the presence of a polar phase and a non-polar phase, the composition according to the invention can implement a nutrient transport concept (NTC). This is because hydrophilic and lipophilic ingredients can dissolve in the polar phase and the non-polar phase, respectively, and are thus absorbed particularly quickly and to a high degree after application. The technology for combining lipophilic and hydrophilic substances in a carrier system can also be referred to as microsolve. + technology. In the case of Microsolve +This technology is a further development of Microsolve technology, in which one or more lipophilic substances are finely dispersed in the aqueous phase using natural, food-specific solubilizers (e.g., soy lecithin) and essentially pre-dissolved (e.g., micellization). This facilitates the dispersion of the lipophilic nutrient in the gastrointestinal tract and thus supports optimal nutrient absorption.

[0013] Efficient absorption of the ingredients is also supported by the ginger extract (Zingiber officinale), which, as a bioenhancer, improves the absorption of ingredients by the human body. The presence of one or more bioenhancers allows the composition according to the invention to implement a nutrient transport concept (NTC). The lipophilic extract from ginger (Zingiber officinale) is preferably an extract from ginger rhizomes, preferably from dried ginger rhizomes. This can be ginger rhizome according to the European Pharmacopoeia. The extract is preferably a CC extraction extract. In the composition, the lipophilic (synonym: nonpolar) phase remains finely and homogeneously dispersed in the aqueous (synonym: polar) phase for an extended period. Thus, the composition according to the invention is physically stable.Only lecithins can be used as emulsifiers, and these can be used in small amounts compared to the substance to be emulsified. For example, the mass of lecithins can be as little as 5% of the mass of the lipid to be emulsified. Another advantage is that lecithins are of natural origin.

[0014] Monohydric alcohols such as ethanol or propanol are not required for the stability of the composition. However, their use in embodiments of the composition according to the invention is not excluded. The same applies to synthetic surfactants. One advantage is that, by omitting monohydric alcohols such as ethanol or propanol, the composition according to the invention is suitable for children, alcoholics, pregnant women, etc. A further advantage is that, by omitting synthetic surfactants, the composition according to the invention is also suitable for people who reject such surfactants.

[0015] The polyol contributes to preservation, and apart from the ingredients mentioned, no additional preservatives are required. This eliminates the need for synthetic or allergenic preservatives.

[0016] Furthermore, lipophilic ingredients sensitive to oxidation and hydrolysis are surprisingly stable despite the presence of water and hydrophilic ingredients. Avoiding oxidation not only increases the amount of available lipophilic ingredients but also prevents the formation of harmful products.

[0017] A stable composition with a polar and a non-polar phase is created using only naturally occurring ingredients. This results in a particularly positive physiological and psychological response and is particularly well tolerated. The composition has a low risk of intolerances such as allergies. In certain embodiments, the two-phase system represents an emulsion.

[0018] Lecithin is a preparation containing phosphatidylcholine as its main ingredient. Phosphatidylcholine is a phospholipid in which phosphoric acid is esterified with diacylglycerol and choline. According to the Food Additives Approval Ordinance (ZZulV 1998), lecithin is a food additive approved under number E 322 for general food use (except for certain foodstuffs).

[0019] The composition according to the invention contains 0.5 g to 10 g, more preferably 1 g to 3.5 g, of lecithin per 100 g of the composition. The lecithin is predominantly present in the boundary region between the polar and non-polar phases. In other words, in addition to the polar phase and the non-polar phase, the composition also comprises a lecithin phase consisting of the lecithin in the composition. The lecithin has a phosphatidylcholine content of 30 wt.% to 100 wt.%. In other words, the composition contains 0.15 g to 10 g, more preferably 0.3 g to 3.5 g, of phosphatidylcholine per 100 g of the composition. In one embodiment, the composition according to the invention contains 1 g to 3 g of phosphatidylcholine per 100 g of the composition. Deoiled lecithin fractions are preferably used as lecithin. This means that the lecithin is preferably essentially free of non-polar lipids such as fatty acids and triglycerides.The content of non-polar lipids such as fatty acids and triglycerides is preferably less than 3% by weight. The lecithin contains a proportion of polar lipids (acetone-insoluble substances) of 90 to 100% by weight. The lecithin can be derived from a source selected from soy, sunflower, rapeseed, fish, milk, eggs, and mixtures thereof, with non-animal sources such as soy, sunflower, and rapeseed being particularly preferred. In addition to the main component, phosphatidylcholine, lecithin may contain, depending on its origin, phosphatidylethanolamine, phosphatidylinositol, phosphatidylserine, sterols, fats, and oils. For example, soy lecithin can contain 40-50% by weight phosphatidylcholine, approximately 10% by weight phosphatidylethanolamine, approximately 5% by weight phosphatidylinositol, approximately 1-2% by weight phosphatidylserine, and also sterols, fats, and oils. Lecithin obtained from egg yolks, on the other hand, consists primarily of phosphatidylcholine. Water and glycerol are components of the polar phase.The non-polar phase can consist of fatty acids and their esters, in particular triglycerides (triacylglycerols) and ethyl esters, fat-soluble vitamins and carotenoids, such as lutein and zeaxanthin, vitamin A (retinol) and its derivatives retinal, retinyl palmitate and retinyl acetate, vitamin E as a collective term for tocopherols and tocotrienols (including alpha-, beta-, gamma-, delta-tocopherols and tocotrienols, both as natural mixtures and synthetically in pure form), vitamin E derivatives such as alpha-, beta-, gamma- and delta-tocopherol acetate (both in optically pure form and as racemate), vitamin D2 (ergocalciferol), vitamin D3 (cholecalciferol), vitamin K1 (phylloquinone), vitamin K2 (menaquinone), vitamin K3 (menadione), coenzyme Q10 H (ubiquinol), ubiquinone-10, and perfluorocarbons. In the present invention, the extract(s) may also be used as a source for the components of the nonpolar phase.

[0020] When calculating the proportion of ingredients in the polar phase based on the total weight of the polar phase, lecithin is not considered a component of the polar phase. When calculating wt%, in cases of doubt, lipophilic compounds containing a phosphate / phosphoric acid residue are considered lecithin and not lipophilic ingredients, unless the description indicates otherwise. Lipophilic substances that do not contain a phosphate / phosphoric acid residue are considered lipophilic ingredients in cases of doubt, unless the description indicates otherwise.

[0021] Embodiments within this document may be combined with one another as desired, unless the subject matter and the description of the embodiments clearly indicate otherwise.

[0022] The verbs "to contain" and "to encompass" and their conjugations also include the verb "to consist of" and its conjugations.

[0023] Preferred embodiments of the invention are specified in the subclaims. In a preferred embodiment, the composition is a liquid at 20°C. Preferably, the liquid has a viscosity of between 100 mPa s and 3000 mPa s at 20°C. The liquid dosage form allows for various possible applications and increases the freedom of movement of the ingredients within the composition, thereby improving their absorption by the human body. By being in liquid form, the composition according to the invention can implement a nutrient transport concept (NTC). This is because the liquid formulation can enable particularly rapid and efficient absorption of the ingredients.

[0024] The viscosity referred to herein is the dynamic viscosity measured according to the method of the European Pharmacopoeia 7.0, 2011, using a cone-and-plate type rotational viscometer.

[0025] The composition preferably contains liposomes. Liposomes can be formed in particular when the composition contains more lecithin / phosphatidylcholine than is required to emulsion the non-polar phase. The emulsifier molecules (lecithin) not required to stabilize the non-polar phase (e.g., fat droplets) can form liposomal structures in the polar phase. These can serve as a special carrier system for the water-soluble, hydrophilic active ingredients, resulting in two special carrier systems: fat droplets for lipophilic active ingredients and liposomes for hydrophilic active ingredients. The formation of liposomes can be supported by using high-pressure homogenizers in the production of the composition. As mentioned at the beginning, the technology for combining lipophilic and hydrophilic substances in a carrier system can also be referred to as microsolve. +-technology. Hydrophilic and lipophilic ingredients can dissolve in the polar phase or the non-polar phase, respectively, and are thus absorbed particularly quickly and to a high degree after application, enabling a nutrient transport concept (NTC) to be implemented. The polyol is preferably one or more compounds selected from glycerin, erythritol, sorbitol, and fructose. These are particularly suitable for stabilizing the composition. Glycerin is particularly preferred as the polyol.

[0026] The polar phase preferably contains 40 wt.% to 96 wt.%, preferably 60 wt.% to 90 wt.%, of polyol, based on the total weight of the polar phase. A corresponding polyol content in the polar phase ensures sufficient preservation of the composition.

[0027] The polar phase contains at least 3 wt.% and less than 20 wt.% water, based on the total weight of the polar phase. Preferably, the polar phase contains 5 wt.% to 17 wt.% water, based on the total weight of the polar phase.

[0028] In a preferred embodiment, the composition contains lutein and zeaxanthin as additional lipophilic ingredients.

[0029] In a preferred embodiment, the composition contains, per 100 g of the composition, 0.01 g to 4.0 g of a mint extract, preferably peppermint (Mentha piperita), as a further lipophilic ingredient. Surprisingly, the mint extract further improves the absorption of the ingredients by the human body. The mint extract thus acts as a bioenhancer. The presence of one or more bioenhancers allows the composition according to the invention to implement a nutrient transport concept (NTC). The mint or peppermint extract is preferably an extract from the aerial parts, preferably the flowering, aerial parts. This can be peppermint oil according to the European Pharmacopoeia. The extract can also be obtained by steam extraction. It is preferably a CC extraction extract.

[0030] In a preferred embodiment, the composition contains, as a further lipophilic ingredient, at least one omega-3 fatty acid selected from docosahexaenoic acid, alpha-linolenic acid, and eicosapentaenoic acid. Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) form an important part of the human diet. The need for omega-3 fatty acids is often not met by dietary habits or options. Available omega-3 preparations, particularly in the form of capsules containing fish oil, are often perceived as indigestible, cause unwanted burping, and smell and taste unpleasantly of fish. Capsules are also rejected due to fear of prions, a vegetarian or vegan lifestyle, or for religious reasons. The direct ingestion of oily substances in general, and oils containing omega-3 fatty acids in particular, is often perceived as unpleasant and / or has negative connotations, which can lead to poor compliance orcontinues to lead to a lack of omega-3 fatty acids. The composition according to the invention masks the taste and odor of these components, thus improving compliance. The composition according to the invention also supports the absorption of these compounds by the human body and allows the oxidation- and hydrolysis-sensitive omega-3 fatty acids or esters to remain surprisingly stable despite the presence of water, hydrophilic ingredients, and oxygen. The nutrient transport concept (NTC) and microsolve technology can enable a particularly high cellular uptake of polyunsaturated fatty acids.

[0031] In a preferred embodiment, the composition contains coenzyme Q10 as a further lipophilic ingredient. The composition according to the invention supports the stability of this compound and its absorption by the human body. The nutrient transport concept (NTC) and microsolve technology can enable particularly high bioavailability of coenzyme Q10.

[0032] Preferably, the at least one hydrophilic ingredient is selected from vitamin C, vitamin B1, vitamin B2, vitamin B3, vitamin B6, vitamin B7 (biotin), vitamin B12, minerals, trace elements and oligomeric proanthocyanidins.

[0033] In a preferred embodiment, the composition contains an isoflavone. The composition preferably contains 0.01 g to 2.0 g of the lipophilic ginger extract per 100 g of the composition. It can best exert its effect in this amount range. The presence of one or more bioenhancers allows the composition according to the invention to implement a nutrient transport concept (NTC).

[0034] In a preferred embodiment, the composition contains, as an additional lipophilic ingredient, 0.5 g to 5.0 g of triacylglycerols, preferably medium-chain triacylglycerols, per 100 g of the composition. Triacylglycerols can serve as carriers for lipophilic ingredients. Their use can stabilize the formulation. Furthermore, the triacylglycerols form an oily film that adheres to the body part over a longer period of time, through which lipophilic ingredients can diffuse and take effect.

[0035] In a preferred embodiment, the composition contains at least one lipophilic ingredient selected from vitamin D2, vitamin D3, derivatives of vitamin D, vitamin A and derivatives thereof, vitamin E and derivatives thereof, vitamin K1, vitamin K2, isoprenoids, curcumin, berry extract, hawthorn extract, and artichoke extract. Curcumin, in particular, can further improve the availability of the ingredients to the human body, which is why curcumin is a preferred lipophilic ingredient. The nutrient transport concept (NTC) and microsolve technology can enable particularly high bioavailability, for example, of the applied vitamin E. The nutrient transport concept (NTC) and microsolve technology can also enable particularly high cellular uptake, for example of phytosterols. Furthermore, the composition according to the invention can implement a nutrient transport concept (NTC) through the presence of one or more bioenhancers.

[0036] In preferred embodiments, the mass ratio of lecithin to lipophilic ingredient(s) in the composition is between 8:1 and 1:20, particularly preferably between 1:1 and 1:12. Preferably, the composition contains no ingredients of animal origin. In other words, the composition is suitable for a vegetarian and / or vegan lifestyle, in particular a vegetarian and / or vegan diet. Vegetarians, and especially vegans, often suffer from a deficiency in certain compounds and corresponding deficiency symptoms due to their limited food supply. It is advantageous that these people can be offered an additional product to ensure a more balanced diet.

[0037] Preferably, the composition does not contain any synthetic surfactant. The term "no" is to be understood as meaning that the concentration of the compound is so low that no significant effect is expected. In other words, the concentration is outside the range at which the compound is normally used. Synthetic surfactants within the meaning of the invention are ethoxylated surfactants, macrogol and derivatives thereof (e.g. macrogolglycerol fatty acid esters such as macrogolglycerol ricinoleate, macrogol fatty acid esters such as macrogol oleate, macrogol fatty alcohol ethers such as polyoxyethylene cetyl ether), propylene glycol and derivatives thereof, polyoxypropylene-polyoxyethylene block polymers, cellulose and derivatives thereof (e.g. hypromellose), benzalkonium, benzethonium, cetylalkonium, cetylpyridinium, cetyltrimethylammonium, dequalinium, sodium dodecyl sulfate, sodium cetyl sulfate, sodium stearyl sulfate, ethylene glycol monostearate, partial fatty acid esters of sorbitan (e.g.Sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan tristearate, sorbitan monooleate, sorbitan sesquioleate, sorbitan trioleate, polysorbates (polyoxyethylene sorbitan fatty acid esters), fatty acid esters of sucrose, fatty acid esters of polyglycerol and da-tocopheryl 1000 succinate.

[0038] Preferably, the composition contains no artificial preservative. The term "no" is to be understood as meaning that the concentration of the compound is so low that no appreciable effect is to be expected. In other words, the concentration is outside the range at which the compound is normally used. Artificial preservatives within the meaning of the invention include 4-hydroxybenzoic acid esters (e.g., methyl 4-hydroxybenzoate and propyl 4-hydroxybenzoate), chlorocresol, chlorobutanol, sorbic acid (E 200), potassium sorbate (E 202), calcium sorbate (E 203), sodium edetate, glycerol triacetate, benzalkonium, benzethonium, cetylalkonium, cetylpyridinium, cetyltrimethylammonium, cetrimonium, chlorhexidine, dequalinium, and organic mercury compounds.

[0039] Preferably, the composition contains no artificial sweetener. The term "no" is to be understood as meaning that the concentration of the compound is so low that no appreciable effect is to be expected. In other words, the concentration is outside the range at which the compound is normally used. Artificial sweeteners within the meaning of the invention are acesulfame (E 950), advantame (E 969), aspartame (E 951), aspartame-acesulfame salt (E 962), cyclamate (E 952), neohesperidin (E 959), neotame (E 961), saccharin (E 954), and sucralose (E 955). Steviol glycosides, e.g., stevioside (E 960), are not considered artificial sweeteners within the meaning of the invention.

[0040] In a preferred embodiment, the composition contains no monohydric alcohol. In a preferred embodiment, the composition contains a maximum of 1 g of monohydric alcohols per 100 g of the composition. Monohydric alcohols within the meaning of this document include, for example, ethanol and propanol.

[0041] In a preferred embodiment, the composition contains no dihydric alcohol. In a preferred embodiment, the composition contains a maximum of 1 g of dihydric alcohols per 100 g of the composition. A dihydric alcohol within the meaning of this document is, for example, propylene glycol.

[0042] Also claimed is a drip device comprising a composition according to the invention, wherein the composition according to the invention is a liquid.

[0043] The invention is further based on the idea of ​​providing a process for producing a composition according to the invention.

[0044] The process for preparing a composition according to the invention preferably comprises the steps of: a) stirring an aqueous solution, wherein the aqueous solution contains lecithin and at least 20% by weight of polyol, at least 3% by weight and less than 20% by weight of water and at least one hydrophilic ingredient, b) adding a lipophilic extract of ginger (Zingiber officinale) and at least one further lipophilic ingredient to obtain a mixture, wherein the mixture contains 0.5 g to 10 g of lecithin per 100 g, c) stirring the mixture and homogenizing under high pressure to obtain the composition according to the invention.

[0045] The processing temperature is preferably adjusted to the lecithin and the lipophilic ingredient to be solubilized. For hydrogenated lecithins, processing temperatures between 40 °C and 80 °C are preferred; for unsaturated lecithins, processing can be carried out at room temperature. Preferably, processing takes place above the melting point of lipophilic ingredients.

[0046] Homogenization is preferably carried out using a high-pressure homogenizer, ultrasound, and / or a rotor-stator mixer, especially a high-pressure homogenizer. A high-pressure homogenizer produces more transparent two-phase systems because the inner phase is more finely dispersed. A high-pressure homogenizer ensures that the composition contains liposomes. Surprisingly, the degree of autoxidation and hydrolysis of the oils, fats, or lipids in the composition according to the invention is low, even though air and water are incorporated using a high-pressure homogenizer.

[0047] Preferably, the process, in particular the stirring and homogenization under high pressure, is carried out under inert gas.

[0048] For further embodiments, advantages and explanations of the method, reference is made to the explanations on the composition.

[0049] The invention is further based on the idea of ​​specifying the use of a composition according to the invention as a dietary supplement or cosmetic preparation. Use as a dietary supplement is particularly preferred. The composition is particularly suitable for use as a dietary supplement and / or cosmetic preparation because it overcomes the disadvantages of conventional products. The composition facilitates the simultaneous provision and good absorption by the human body of hydrophilic and lipophilic ingredients. Using only naturally occurring ingredients and without the use of mono- or dihydric alcohols, synthetic surfactants, or preservatives, a physically, chemically, and microbially stable composition is formed that facilitates the absorption of ingredients by the human body particularly well.The composition has been particularly well-received physiologically and psychologically and is particularly well-tolerated. The taste and smell are not perceived as unpleasant, but rather as very pleasant. When taken orally, burping is prevented. Since no (gelatin) capsules are used, the preparations according to the invention are also available to people who reject capsules for fear of prions, due to a vegetarian or vegan lifestyle, or for religious reasons. The two-phase system has a favorable viscosity.

[0050] The use preferably comprises topical or oral, particularly preferably oral, application.

[0051] For further embodiments, advantages and explanations, please refer to the explanations on the composition.

[0052] The invention is explained in more detail below using exemplary embodiments.

[0053] Example 1:

[0054] 2.5 g of soy lecithin with a phosphatidylcholine content of 45% and 0.2 g of vitamin B2 are completely dispersed in 92 g of an 85% (wt%) aqueous glycerol solution while stirring at 50 °C. 0.3 g of a lipophilic ginger extract and 5 g of vitamin E acetate are then added to this dispersion and stirred until homogeneous at 50 °C. Finally, homogenization is carried out using a high-pressure homogenizer.

[0055] The result is a stable dispersion whose components can be particularly well absorbed by the human body.

[0056] Example 2:

[0057] 2 g of sunflower lecithin with a phosphatidylcholine content of 75% and 0.5 g of niacinamide are completely dispersed in 85.5 g of an 85% (wt%) aqueous glycerol solution while stirring at 50 °C.

[0058] 0.5 g of a lipophilic ginger extract, 2 g of coenzyme Q10, and 10 g of algal oil are then added to this dispersion and stirred until homogeneous at 50 °C. Finally, homogenization is performed using a high-pressure homogenizer.

[0059] The result is a stable dispersion whose components can be particularly well absorbed by the human body.

Claims

Claims 1. A composition, wherein the composition comprises a polar phase and a non-polar phase, wherein the composition contains a lipophilic extract of ginger (Zingiber officinale) and at least one further lipophilic ingredient, the polar phase contains, based on the total weight of the polar phase, at least 20 wt% polyol, at least 3 wt% and less than 20 wt% water and at least one hydrophilic ingredient, and the composition contains 0.5 g to 10 g of lecithin per 100 g of the composition.

2. Composition according to at least claim 1, characterized in that the composition has a viscosity of between 100 mPa ■ s and 3000 mPa ■ s at 20 °C.

3. Composition according to at least claim 1 or 2, characterized in that the composition contains an isoflavone.

4. Composition according to at least one of claims 1 to 3, characterized in that the composition contains liposomes.

5. Composition according to at least one of claims 1 to 4, characterized in that the polar phase contains 40 wt.% to 96 wt.%, preferably 60 wt.% to 90 wt.%, of polyol, based on the total weight of the polar phase.

6. Composition according to at least one of claims 1 to 5, characterized in that the polyol is glycerol.

7. Composition according to at least one of claims 1 to 6, characterized in that the composition contains lutein and zeaxanthin.

8. Composition according to at least one of claims 1 to 7, characterized in that the composition contains per 100 g of the composition 0.01 g to 4.0 g of an extract from mint, preferably from peppermint (Mentha piperita).

9. Composition according to at least one of claims 1 to 8, characterized in that the composition contains an omega-3 fatty acid selected from docosahexaenoic acid, alpha-linolenic acid and eicosapentaenoic acid.

10. Composition according to at least one of claims 1 to 9, characterized in that the composition contains coenzyme Q10.

11. Composition according to at least one of claims 1 to 10, characterized in that the composition contains as hydrophilic ingredient at least one ingredient selected from vitamin C, vitamin B1, vitamin B2, vitamin B3, vitamin B6, vitamin B7 (biotin), vitamin B12, minerals, trace elements and oligomeric proanthocyanidins.

12. Composition according to at least one of claims 1 to 11, characterized in that the composition contains 0.01 g to 2.0 g of the lipophilic extract from ginger per 100 g of the composition.

13. Composition according to at least one of claims 1 to 12, characterized in that the composition contains 0.5 g to 5.0 g of triacylglycerols, preferably medium-chain triacylglycerols, per 100 g of the composition.

14. Composition according to at least one of claims 1 to 13, characterized in that the composition contains at least one lipophilic ingredient selected from vitamin D2, vitamin D3, derivatives of vitamin D, vitamin A and derivatives thereof, vitamin E and derivatives thereof, vitamin K1, vitamin K2, isoprenoids, curcumin, berry extract, hawthorn extract and artichoke extract.

15. Composition according to at least one of claims 1 to 14, characterized in that the composition contains curcumin.