Method for determining the secretory state in human milk using infrared spectroscopy

ES3075210A1Undetermined Publication Date: 2026-07-28FUNDACION PARA LA INVESTIGACION DEL HOSPITAL UNIVERSITARIO Y POLITECNICO LA FE DE LA COMUNIDAD VALENCIANA (90 00) +1
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Patent Information

Application Number
ES2025030064
Authority / Receiving Office
ES · ES
Patent Type
Applications
Current Assignee / Owner
Filing Date
2025-01-28
Publication Date
2026-07-28

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Abstract

Method for determining the secretory state in human milk using infrared spectroscopy. The present invention relates to a method for determining the maternal secretory phenotype in a human milk (HM) sample by IR spectroscopy, comprising the steps of (a) obtaining an HM sample; (b) subjecting the HM sample to IR spectroscopy analysis to generate an IR spectrum in the range of 4000 to 400 cm-1, wherein signals in this region are associated with the presence of specific HMOs; (c) comparing the IR spectrum of the HM sample obtained in (b) with a discriminatory model, wherein the discriminatory model uses a set of IR spectra of HM samples with a known maternal secretory phenotype recorded in the same spectral range; and (d) determining the maternal secretory phenotype of the HM sample as secretor (Se+) or non-secretor (Se-) based on the differences determined in (c).
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