New compound as an mTOR inhibitor and its use

ES3078903T3Undetermined Publication Date: 2026-09-18MEDICINAL BIOCONVERGENCE RESEARCH CENTER (50 00) +1
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Patent Information

Application Number
ES2019792007T
Authority / Receiving Office
ES · ES
Patent Type
Patents
Current Assignee / Owner
Priority Date
2018-04-26
Filing Date
2019-04-26
Publication Date
2026-09-18
Estimated Expiration
2039-04-26

AI Technical Summary

Technical Problem

Current treatments for brain diseases related to the mTOR pathway, such as epilepsy, Alzheimer's disease, and Parkinson's disease, are inadequate, particularly for drug-resistant cases, and there is a need for compounds that can effectively inhibit mTOR activity and cross the blood-brain barrier.

Method used

Development of novel compounds represented by Formula 1, which inhibit mTOR activity and possess high blood-brain barrier permeability, allowing for therapeutic effects on brain diseases associated with the mTOR pathway.

Benefits of technology

The compounds effectively inhibit mTOR activity, providing therapeutic benefits for brain diseases like epilepsy, Alzheimer's, and Parkinson's by crossing the blood-brain barrier, addressing the limitations of existing treatments.

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Abstract

The present invention relates to a novel compound as an mTOR inhibitor and to a use thereof and, more specifically, to a novel compound represented by formula 1 exhibiting mTOR inhibitory activity and to a pharmaceutical composition comprising it as an active ingredient for preventing or treating brain diseases associated with an mTOR pathway.
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