NK cell cryopreservation solution, NK cell cryopreservation process, pharmaceutical agent and combined pharmaceutical agent and their application

Abstract

This disclosure provides an NK cell cryopreservation solution, an NK cell cryopreservation method, a pharmaceutical agent, and a combined pharmaceutical agent and their application. The NK cell cryopreservation solution includes: a base solution, including methylcellulose and dimethyl sulfoxide; and human serum albumin. The NK cell cryopreservation solution of this disclosure is capable of improving the recovery rate of NK cell activity after cryopreservation, reducing cell damage, and enabling NK cells to retain high destructive activity and proliferative capacity after thawing and culture.Furthermore, the NK cell cryopreservation solution, with simple and reliable components, is suitable for direct perfusion into the human body, easy to prepare and store, and lends itself to large-scale cell cryopreservation and clinical application, thus exhibiting high application value.

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