Monoclonal antibody or antigen-binding fragment thereof that specifically binds to TNF-like ligand (TL1A), and use thereof

Abstract

Abstract Monoclonal antibody or antigen-binding fragment thereof that specifically binds to TNF-like ligand 1A (TL1A) and its use The present invention relates to the field of biotechnology and medicine, in particular, to a monoclonal antibody or antigen-binding fragment thereof that specifically binds to TNF-like ligand 1A (TL1A).In addition, the invention relates to nucleic acids encoding said antibody, expression vectors, host cells and methods of obtaining them, methods of obtaining antibodies according to the invention, pharmaceutical compositions containing an antibody according to the invention or an antigen-binding fragment thereof, as well as pharmaceutical compositions containing an antibody according to the invention or an antigen-binding fragment thereof and other therapeutically active compounds; Methods for treating diseases or disorders mediated by TL1A, the use of an antibody or antigen-binding fragment thereof or a pharmaceutical composition thereof for treating diseases or disorders mediated by TL1A, and the use of an antibody or antigen-binding fragment thereof and other therapeutically active compounds according to the invention for treating diseases or disorders mediated by TL1A.