Contact lens package

Abstract

According to an embodiment of the present invention, there is provided a contact lens package comprising: a package having a cover member and a bottom member; and a contact lens housed in a deformed state in a housing space sealed by the cover member and the bottom member, the contact lens having a relaxation modulus of 1.6 MPa or less. The relaxation modulus of the contact lens is an elastic modulus after one second elapsed from the start of measurement when the stress necessary for holding the contact lens is measured while applying a strain of 75% with respect to the upper limit of a linear elastic region in a tensile test to the contact lens in a 35 DEG C aqueous medium.

Description

(19) State Intellectual Property Office (12) Invention Patent Application (10) Application Publication Number (43) Application Publication Date (21) Application Number 202480055793.9 (22) Application Date 2024.12.25 (30) Priority Data 2023-220877 2023.12.27 JP (85) PCT International Application Entering National Phase Date 2026.02.28 (86) PCT International Application Application Data PCT / JP2024 / 045828 2024.12.25 (87) PCT International Application Publication Data WO2025 / 142986 JA 2025.07.03 (71) Applicant: Meritsu Co., Ltd. Address: Aichi Prefecture, Japan (72) Inventors: Hiroki Kono, Yoshihiro Tomono (74) Patent Agency: Beijing Sanyou Intellectual Property Agency Co., Ltd. 11127 Patent Attorney Wu Fei, Chu Yao, Yang (51) Int.Cl. G02C 7 / 04 (2006.01) B65D 75 / 32 (2006.01) B65D 81 / 22 (2006.01) B65D 85 / 38 (2006.01) G02C 11 / 00 (2006.01) (54) Invention Title: Contact Lens Packaging (57) Abstract: According to an embodiment of the present invention, a contact lens packaging is provided, comprising: a package having a cover member and a bottom member; and a contact lens, which is housed in a deformable state in a storage space sealed by the cover member and the bottom member, wherein the relaxation modulus of the contact lens is 1.6 MPa or less, and the relaxation modulus of the contact lens is 75% of the upper limit of the linear elastic region in a tensile test when the contact lens is subjected to a tensile test in an aqueous medium at 35°C. The elastic modulus after 1 second from the start of the measurement is measured when the strain required to retain the contact lens is applied simultaneously with the strain. Claims 2 pages Description 17 pages Drawings 6 pages CN 121752940 A 2026.03.27 CN 1 21 75 29 40 A 1. A contact lens package comprising: a package having a cover part and a bottom part; and a contact lens housed in a deformable state in a storage space sealed by the cover part and the bottom part, wherein the relaxation modulus of the contact lens is 1.6 MPa or less, and the relaxation modulus of the contact lens is the elastic modulus after 1 second from the start of the measurement when the strain required to retain the contact lens is applied simultaneously with the strain relative to 75% of the upper limit of the linear elastic region in a tensile test in an aqueous medium at 35°C. 2. The contact lens package according to claim 1, wherein the loss tangent of the tensile strength of the contact lens, obtained by dynamic tensile viscoelasticity measurement in an aqueous medium at 35°C, is 0.14 or less.3. The contact lens packaging according to claim 1, wherein the relaxation modulus of the contact lens is 1.3 MPa or less. 4. A contact lens packaging comprising: a package having a cap and a bottom; and a contact lens housed in a deformed state within a storage space sealed by the cap and the bottom, wherein the loss tangent of the contact lens, as determined by dynamic tensile viscoelasticity measurement in an aqueous medium at 35°C, is 0.1 or less. 5. The contact lens packaging according to claim 4, wherein the loss tangent of the contact lens, as determined by dynamic tensile viscoelasticity measurement, is 0.06 or less. 6. The contact lens packaging according to claim 4, wherein the relaxation modulus of the contact lens is 1.8 MPa or less, and the relaxation modulus of the contact lens is the elastic modulus after 1 second from the start of the measurement when a strain of 75% relative to the upper limit of the linear elastic region in the tensile test is applied to the contact lens in an aqueous medium at 35°C, and the stress required to hold the contact lens is measured at the start of the measurement. 7. A contact lens packaging comprising: a package having a cap and a bottom part; and a contact lens housed in a deformable state within a storage space sealed by the cap and the bottom part, wherein the contact lens has a loss tangent of less than 0.1 as determined by dynamic tensile viscoelasticity measurement in an aqueous medium at 35°C, and a relaxation modulus of less than 1.6 MPa, wherein the relaxation modulus of the contact lens is the elastic modulus after 1 second from the start of the measurement when a strain of 75% relative to the upper limit of the linear elastic region in the tensile test is applied to the contact lens in an aqueous medium at 35°C, and the stress required to hold the contact lens is measured. 8. The contact lens packaging according to claim 7, wherein the loss tangent of the contact lens is less than 0.06. 9. The contact lens packaging according to claim 7, wherein the relaxation modulus of the contact lens is less than 1.2 MPa. 10. The contact lens packaging according to claim 1, 4, or 7, wherein the oxygen permeability (Dk / t) of the contact lens is 24 or higher. 11. The contact lens packaging according to claim 1, 4, or 7, wherein the contact lens is a silicone hydrogel lens. 12. The contact lens packaging according to claim 1, 4, or 7, wherein the contact lens is housed in the storage space with a height less than its natural sagittal height. Claims 1 / 2 page 2 CN 121752940 A 13. The contact lens packaging according to claim 1, 4, or 7, wherein the height of the storage space is less than 2 mm. 14. A method for improving the resilience of contact lenses to wrinkles when opening a contact lens packaging, comprising: connecting an opposing cap member and a bottom member in such a manner as to form a sealed storage space in which a contact lens is disposed.The packaging for the contact lenses is manufactured in a manner in which the height of the storage space is less than the natural sagitta of the contact lenses, and the relaxation modulus of the contact lenses is less than 1.6 MPa. The relaxation modulus of the contact lenses is the elastic modulus after 1 second from the start of the measurement when the contact lens is subjected to a strain of 75% relative to the upper limit of the linear elastic region in the tensile test in an aqueous medium at 35°C. 15. A method for suppressing wrinkling of contact lenses in a contact lens package, comprising: forming a contact lens package by joining opposing cap and bottom parts to form a storage space in which a contact lens is disposed, the height of the storage space being less than the natural sag of the contact lens, the method satisfying at least one of (i) and (ii) below, (i) the loss tangent of the stretching of the contact lens, as determined by dynamic tensile viscoelasticity measurement in an aqueous medium at 35°C, is 0.1 or less; (ii) the proportion of energy released to shrink from the stretched state to 0% of the stretching ratio relative to the energy absorbed when the contact lens is stretched at 100% in an aqueous medium at 35°C is 90% or more. 16. A contact lens package comprising: a package having a cap and a bottom; and a contact lens housed in a storage space sealed by the cap and the bottom, the storage space being defined by a convex curved portion of the cap protruding toward the bottom and a concave curved portion of the bottom protruding toward the opposite side of the cap, configured such that the contact lens is attached to the cap or the bottom when the package is opened, the contact lens package satisfying at least one of (i) and (ii) below: (i) the relaxation modulus of the contact lens is 1.6 MPa or less, the relaxation modulus of the contact lens being the elastic modulus after 1 second from the start of the measurement when a strain of 75% relative to the upper limit of the linear elastic region in a tensile test is applied to the contact lens in an aqueous medium at 35°C; (ii) the loss tangent of the contact lens under tension, as determined by dynamic tensile viscoelasticity measurement in an aqueous medium at 35°C, is 0.1 or less. Claims 2 / 2 pages 3 CN 121752940 A Contact Lens Packaging Technology Field

[0001] This invention relates to a contact lens packaging. Background Art

[0002] Conventional disposable contact lenses are usually stored together with a storage solution in the lens storage space of a package. This package consists of a cover material and a base material, and has a lens storage space that is higher than the natural height of the contact lens.

[0003] In recent years, from the perspective of reducing plastic waste and saving space, thin contact lens packaging has been proposed.Contact lenses are stored in a thin package with a thickness smaller than the natural sagitta of the contact lens (e.g., Patent Document 1).

[0004] Prior Art Documents

[0005] Patent Documents

[0006] Patent Document 1: Japanese Patent Application Publication No. 2005-234576 Summary of the Invention

[0007] Problems to be Solved by the Invention

[0008] When contact lenses are taken out of a thin contact lens package for wearing, blurriness is sometimes felt in the initial stage of wearing. The main object of the present invention is to improve the blurriness of contact lenses taken out of a thin contact lens package in the initial stage of wearing.

[0009] Means for solving the problem

[0010] [1] According to one aspect of the present invention, a contact lens package is provided, comprising: a package having a cover member and a bottom member; and a contact lens, which is housed in a deformed state in a storage space sealed by the cover member and the bottom member, wherein the relaxation modulus of the contact lens is 1.6 MPa or less, and the relaxation modulus of the contact lens is the elastic modulus after 1 second from the start of the measurement when a strain of 75% relative to the upper limit of the linear elastic region in a tensile test is applied to the contact lens in an aqueous medium at 35°C, and the stress required to hold the contact lens is measured.

[0011] [2] According to the contact lens package of [1] above, wherein the loss tangent of the stretching of the contact lens obtained by dynamic tensile viscoelasticity measurement in an aqueous medium at 35°C can be 0.14 or less.

[0012] [3] According to the contact lens package of [1] or [2] above, wherein the relaxation modulus of the contact lens can be 1.3 MPa or less.

[0013] [4] According to another aspect of the present invention, a contact lens packaging is provided, comprising: a package having a cover member and a bottom member; and a contact lens, which is housed in a deformed state in a storage space sealed by the cover member and the bottom member, wherein the loss tangent of the contact lens obtained by dynamic tensile viscoelasticity measurement in an aqueous medium at 35°C is 0.1 or less.

[0014] [5] According to the contact lens packaging of [4] above, wherein the loss tangent of the contact lens is 0.06 or less.

[0015] [6] According to the contact lens packaging of [4] or [5] above, wherein the relaxation modulus of the contact lens is 1.8 MPa or less, wherein the relaxation modulus of the contact lens is the elastic modulus after 1 second from the start of the measurement when a strain of 75% relative to the upper limit of the linear elastic region in the tensile test is applied to the contact lens in an aqueous medium at 35°C. Instruction manual 1 / 17 pages 4 CN 121752940 A

[0016] [7] According to another aspect of the present invention, a contact lens packaging is provided, comprising: a package having a cover componentThe contact lens is housed in a deformed state in a storage space sealed by the cover and the bottom components. The contact lens, measured by dynamic tensile viscoelasticity testing in an aqueous medium at 35°C, has a loss tangent of 0.1 or less and a relaxation modulus of 1.6 MPa or less. The relaxation modulus of the contact lens is the elastic modulus after 1 second from the start of the measurement when a strain of 75% relative to the upper limit of the linear elastic region in the tensile test is applied to the contact lens in an aqueous medium at 35°C.

[0017] [8] According to the contact lens packaging described in [7] above, the loss tangent of the contact lens can be 0.06 or less.

[0018] [9] According to the contact lens packaging described in [7] or [8] above, the relaxation modulus of the contact lens can be 1.2 MPa or less.

[0019]

[10] According to any one of [1] to [9] above, the oxygen permeability (Dk / t) of the contact lens can be 24 or more.

[0020]

[11] According to any one of [1] to

[10] above, the contact lens can be a silicone hydrogel lens.

[0021]

[12] According to any one of [1] to

[11] above, the contact lens can be stored in the storage space with its height less than its natural height.

[0022]

[13] According to any one of [1] to

[12] above, the height of the storage space can be 2 mm or less.

[0023]

[14] According to another aspect of the present invention, a method for improving the resilience of contact lenses when opening a contact lens package is provided, comprising: joining opposing cover members and bottom members to form a storage space in which a contact lens is disposed in a sealed state to manufacture a contact lens package, wherein the height of the storage space is less than the natural sagitta of the contact lens, and the relaxation modulus of the contact lens is 1.6 MPa or less, wherein the relaxation modulus of the contact lens is the elastic modulus after 1 second from the start of the measurement when a strain of 75% relative to the upper limit of the linear elastic region in a tensile test is applied to the contact lens in an aqueous medium at 35°C, and the stress required for the retention of the contact lens is measured.

[0024]

[15] According to another aspect of the present invention, a method for suppressing the formation of wrinkles in a contact lens package is provided, comprising: joining opposing cover members and bottom members to form a storage space in which a contact lens is disposed in a sealed state to manufacture a contact lens package, wherein the height of the storage space is less than the natural sagitta of the contact lens.However, the method satisfies at least one of the following (i) and (ii): (i) the loss tangent of the stretching of the contact lens obtained by dynamic stretching viscoelasticity measurement in an aqueous medium at 35°C is 0.1 or less; (ii) the proportion of energy released to shrink from the stretched state to 0% of the stretching ratio when the contact lens is stretched at 100% in an aqueous medium at 35°C is 90% or more, relative to the energy absorbed.

[0025]

[16] According to another aspect of the present invention, a contact lens packaging is provided, comprising: a package having a cover member and a bottom member; and a contact lens, which is housed in a storage space sealed by the cover member and the bottom member, the storage space being defined by a convex curved surface of the cover member protruding toward the bottom member and a concave curved surface of the bottom member protruding toward the side opposite to the cover member, the contact lens packaging being configured such that when the package is opened, the contact lens is attached to the cover member or the bottom member, the contact lens packaging satisfying at least one of the following (i) and (ii): (i) the relaxation modulus of the contact lens is 1.6 MPa or less, the relaxation modulus of the contact lens being the elastic modulus after 1 second from the start of the measurement when a strain of 75% relative to the upper limit of the linear elastic region in the tensile test is applied to the contact lens in an aqueous medium at 35°C; (ii) The loss tangent of the stretching of the above-mentioned contact lens, as determined by dynamic tensile viscoelasticity measurement in an aqueous medium at 35°C, is 0.1 or less.

[0026] Effects of the Invention

[0027] According to an embodiment of the present invention, a contact lens with specified physical properties is used as a contact lens housed in a thin package. As a result, even when the contact lens is taken out of the thin package and worn immediately, the initial blurring after wearing can be improved.

[0028] From the perspective of the relationship between the thinness of the packaging and the reduction of waste such as plastics, the thin contact lens packaging of the embodiment of the present invention also contributes to "12. Responsible consumption and production" and "14. Protecting the richness of the ocean" in particular among the 17 goals & 169 sub-goals of the SDGs (Sustainable Development Goals). Brief Description of the Drawings

[0029] FIG1A is a schematic top view of a contact lens package according to an embodiment of the present invention.

[0030] FIG1B is a schematic bottom view of the contact lens package shown in FIG1A.

[0031] FIG1C is a schematic cross-sectional view along line A-A of the contact lens package shown in FIG1A.

[0032] FIG1D is an exploded perspective view of the contact lens package shown in FIG1A.

[0033] FIG2 is a schematic perspective view of an example of the package in an opened state.

[0034] FIG3 is a diagram illustrating the natural sagitta of the contact lens.

[0035] Figure 4A is a schematic cross-sectional view of the lens loading substrate used in the contact lens packaging shown in Figure 1A.

[0036] Figure 4B is a schematic cross-sectional view of an example of the lens loading substrate.

[0037] Figure 5 is a schematic cross-sectional view of a contact lens packaging according to an embodiment of the present invention.

[0038] Figure 6 is a schematic cross-sectional view of the bottom component of the contact lens packaging shown in Figure 5.

[0039] Figure 7 is a schematic cross-sectional view of a contact lens packaging according to an embodiment of the present invention.

[0040] Figure 8(a) is a schematic cross-sectional view of the cover component of the contact lens packaging shown in Figure 7, and Figure 8(b) is a schematic cross-sectional view of the bottom component of the contact lens packaging shown in Figure 7.

[0041] Figure 9 is a diagram illustrating the method for preparing the test sample.

[0042] Figure 10(a) is a diagram showing the power distribution of contact lenses with a Q value of 2 or higher in all ring regions, and Figure 10(b) is a diagram showing the power distribution of contact lenses with a Q value of 2 or lower in all ring regions. Detailed Description of Embodiments

[0043] Hereinafter, representative embodiments of the present invention will be described, but the present invention is not limited to these embodiments. Each embodiment can be appropriately combined except in cases where it is obviously unsuitable. For ease of observation, the accompanying drawings are shown schematically, and the thickness and dimensions of each component and the ratios of the thicknesses between the components in the drawings are different from the actual figures.

[0044] In this specification, the surface of the contact lens that contacts the eye is sometimes referred to as the inner surface, and the surface on the opposite side is referred to as the outer surface.

[0045] In this specification, "monomer" refers to a polymeric compound having one or more polymerizable groups. As polymerizable groups, olefinic unsaturated groups are preferably exemplified, and polymerizable groups may be, for example, (meth)acryloyl, vinyl, styrene, alkenyl, or allyl. Here, "(meth)" refers to optional methyl substitution. Thus, "(meth)acryloyl" refers to methacryloyl and / or acryloyl. The same applies to other designations such as "(meth)acrylic acid".

[0046] [Contact Lens Packaging]

[0047] According to one aspect of the present invention, a contact lens packaging is provided, comprising: a package having a cap member and a bottom member; and a contact lens housed in a storage space sealed by the cap member and the bottom member. In the sealed storage space, the contact lens may be in a deformed state, at least partially deformed. The deformation of the contact lens can be any deformation that allows it to return to a wearable state after the storage space is opened, and may be a bent, twisted, flexed, flattened, or rolled state, etc., of at least a portion of a hemispherical shape formed along the corneal curve. For example, the contact lens may be in a state where its height is less than its natural sagittal height and / or its diameter is less than its natural diameter (DIA) in the sealed storage space.

[0048] The standard deviation of the diopter distribution in a specified area of ​​the contact lens immediately after the contact lens packaging of the embodiment of the present invention is opened (e.g., within 15 seconds after opening) is typically 3 or less, for example 2 or less, preferably 1.5 or less, more preferably 1 or less, and even more preferably 0.5 or less. There is no particular limitation on the lower limit of the standard deviation of the above-mentioned diopter distribution; for example, it can be 0.01 or more. A small standard deviation of the above-mentioned diopter distribution means that the diopter unevenness on the surface of the contact lens is small, and as a result, the aforementioned blurring can be reduced. The standard deviation of the above-mentioned diopter distribution can be obtained as a Q value, for example, by measuring it using an underwater power meter (Visionics, "VC-2001"). The specified area that is the object of the above-mentioned diopter distribution measurement can be, for example, a ring area with a radius of 5 mm or less from the center of the contact lens, a dot area with a radius of 5 mm or less, or a dot area with a radius of 3 mm or less.

[0049] The standard deviation of the power distribution in a specified area of ​​the contact lens after 900 seconds following the opening of the contact lens packaging according to the embodiments of the present invention is typically 3 or less, for example, 2 or less, preferably 1.5 or less, more preferably 1 or less, and even more preferably 0.5 or less. The lower limit of the standard deviation of the power distribution is not particularly limited; for example, it can be 0.01 or more.

[0050] FIG1A is a schematic top view of a contact lens packaging according to an embodiment of the present invention, FIG1B is a schematic bottom view of the contact lens packaging shown in FIG1A, FIG1C is a schematic cross-sectional view along line A-A of the contact lens packaging shown in FIG1A, and FIG1D is an exploded perspective view of the contact lens packaging shown in FIG1A. Additionally, FIG2 is a schematic perspective view of an example of the packaging in an opened state.

[0051] As shown in Figures 1A to 1D, the contact lens packaging 200A includes: packaging 100 having a cover member 10 and a bottom member 20; and contact lenses 120 housed in a storage space 110 sealed by the cover member 10 and the bottom member 20. Although not shown, contact lens preservation solution is also housed in the storage space 110, thereby maintaining the contact lenses 120 in a hydrated state. The contact lenses 120 are housed in the storage space 110 in a deformed state, specifically in a state where their height is less than their natural sagitta, for example, they may be in a flattened state. Here, the natural sagitta of the contact lens refers to the height of the outer surface of the lens when the hydrated contact lens is placed in a horizontal plane with the inner surface facing down, which is the height indicated by "T" in Figure 3.

[0052] As shown in Figures 1A to 1D and Figure 2, the packaging 100 is composed of a cover member 10 and a bottom member 20.

[0053] The cover member 10 is, for example, made of a flexible film substrate. Materials that can be used to form film substrates include inorganic materials such as aluminum, polyolefin resins such as polyethylene (PE) and polypropylene (PP), and polyesters such as polyethylene terephthalate (PET).Resin materials such as resins and polyamide resins.

[0054] The film substrate can have a single-layer structure or a multilayer structure. In one embodiment, the film substrate can have a single-layer structure made of a resin film (e.g., PP film, PET film) or a metal foil (e.g., aluminum foil). In another embodiment, the film substrate can have a two-layer structure comprising a resin layer (e.g., PP film, PET film) and an aluminum layer (e.g., aluminum vapor deposited layer) disposed on one side thereof. In another embodiment, the film substrate can have a three-layer structure comprising a first resin layer, an aluminum layer, and a second resin layer.

[0055] In the example shown, the bottom component 20 includes a support substrate 22 and a lens loading substrate 24 disposed on the inner surface of the support substrate 22. The lens loading substrate 24 is fixed to a predetermined position on the support substrate 22, for example, by an adhesive. The lens loading substrate 24 is an optional component and can be omitted depending on the purpose.

[0056] The support substrate 22 is, for example, made of a flexible film substrate, the same as that constituting the cover member 10.

[0057] The lens loading substrate 24 in the figure example has a circular lens loading portion 24a and an edge portion 24b arranged to surround its outer periphery and having a maximum height T2 that is higher than the maximum height T1 of the lens loading portion 24a (Figures 1D, 2, and 4A). In a sealed contact lens package, the contact lens is typically loaded on the lens loading portion 24a of the lens loading substrate 24. The lens loading substrate 24 is formed, for example, from a resin material such as PE, PP, or PET, and has mechanical strength and shape retention capable of supporting the contact lens.

[0058] The shape of the lens loading substrate 24 is not limited to the example shown in the figure. For example, the lens loading substrate can be non-circular (e.g., elliptical, polygonal, etc.). In addition, for example, the lens loading portion can be planar, or it can be convex or concave upward depending on the purpose. Specifically, as shown in Figure 4B, the lens loading portion 24a can also be convex upward. Additionally, for example, the lens mounting substrate may not have an edge portion.

[0059] The thickness of the lens mounting portion 24a is, for example, 0.1 mm to 1.0 mm, preferably 0.2 mm to 0.9 mm.

[0060] The lens mounting substrate 24 may also have a through hole 24c extending through the lens mounting portion 24a in the thickness direction, as shown in the example figure. One or more through holes may be provided.

[0061] The storage space 110 sealed by the cover member 10 and the bottom member 20 can be formed by joining the cover member 10 and the bottom member 20 (more specifically, the cover member 10 and the support substrate 22) in a manner that surrounds a defined area. For example, with a contact lens disposed at a defined position on the bottom member (e.g., on the lens mounting portion of the lens mounting substrate), the cover member and the bottom member are joined together.The components are joined at least in a defined area surrounding the lens loading substrate (e.g., area S in FIG. 2), thereby enabling a contact lens package in which a contact lens is stored in a storage space sealed by the cover component and the bottom component. From the viewpoint of sealing and ease of opening, the joining is preferably performed by heat sealing or ultrasonic sealing, and heat sealing is more preferred. In the example of the contact lens package 200A, the portions of the upper surface (cover component 10) and the bottom surface (bottom component 20) corresponding to the lens loading substrate 24 protrude, but the contact lens package of this embodiment is not limited to this configuration. For example, the contact lens package may be configured such that one side has a protrusion corresponding to the contact lens or lens loading substrate 24, and the other side is flat.

[0062] The height of the storage space 110 may correspond to the value obtained by subtracting the total thickness of the cover component and the bottom component from the maximum thickness of the portion of the contact lens package 200A corresponding to the storage space 110. Here, when the bottom component 20 includes the support substrate 22 and the lens loading substrate 24, the thickness of the bottom component 20 may be set as the sum of the thickness of the support substrate 22 and the maximum height T1 of the lens loading portion 24a.

[0063] The height of the storage space (maximum height) is typically less than the natural sagitta of the contact lens, for example, 4.5 mm or less, preferably 3 mm or less, more preferably 2.5 mm or less, and can be 2 mm or less, 1.5 mm or less, 1.2 mm or less, 1 mm or less, or 0.9 mm or less. The height of the storage space is, for example, 0.2 mm or more, and can be 0.3 mm or more, 0.4 mm or more, 0.5 mm or more, 0.6 mm or more, 0.8 mm or more, 1 mm or more, 1.2 mm or more, 1.4 mm or more, 1.6 mm or more, 1.8 mm or more, or 2 mm or more. If the height of the storage space is within the above range, the thinness of the contact lens packaging and the suppression of lens wrinkles can be balanced, and as a result, the effects of the present invention can be appropriately obtained. As for the packaging having such a height of storage space, it is not limited to the configuration shown in the example, and for example, the configuration described in Japanese Patent Application Publication No. 2005-234576 can also be used. Instruction manual, page 5 / 17, CN 121752940 A

[0064] FIG5 is a schematic cross-sectional view showing the configuration of a contact lens package according to another embodiment of the present invention. The contact lens package 200B includes: a package 100 having a cap member 10 and a bottom member 20; and a contact lens 120 housed in a storage space 110 sealed by the cap member 10 and the bottom member 20. Although not shown, contact lens preservation solution is also housed in the storage space 110, thereby maintaining the contact lens 120 in a hydrated state. The contact lens 120 is housed in the storage space 110 in a deformed state, specifically in a state where its height is smaller than its natural sagittal height, for example, it may be in a flattened state.

[0065] The cover member 10 is, for example, made of a flexible film substrate. The material forming the film substrate is as described in the description of the contact lens packaging 200A.

[0066] The bottom member 20 is typically relatively thick and has shape retention. For example, as shown in FIG6, the bottom member 20 has a concave receiving recess 26 for receiving contact lenses and a storage solution, and a flat flange 27 arranged to surround the receiving recess 26. The receiving recess 26 and the flange 27 are integrally molded, for example, by injection molding of synthetic resins such as polyethylene (PE), polypropylene (PP), and polyethylene terephthalate (PET). The thickness of the bottom member 20 can be, for example, 0.1 mm to 2 mm, preferably 0.2 mm to 1 mm.

[0067] The cover member 10 is arranged to cover the upper surface of the bottom member 20 in a substantially flat manner. The cover member 10 is peelably engaged with the bottom member 10 at least in the entire circumference of the area surrounding the receiving recess 26, and is stacked on the bottom member 10 without engagement in at least one end region. The engagement of the bottom member and the cover member can be achieved, for example, by heat sealing, ultrasonic sealing, etc.

[0068] The receiving space 110 is the space defined by the receiving recess 26 and the cover member 10. The height (maximum height) of the receiving space is typically less than the natural sagitta of the contact lens, for example, 4.5 mm or less, preferably 3 mm or less, more preferably 2.5 mm or less, and can be 2 mm or less or 1.5 mm or less. The height of the receiving space is, for example, 0.2 mm or more, and can be 0.3 mm or more, 0.4 mm or more, 0.5 mm or more, 0.6 mm or more, 0.8 mm or more, 1 mm or more, 1.2 mm or more, 1.4 mm or more, 1.6 mm or more, 1.8 mm or more, or 2 mm or more. If the height of the storage space is within the above range, the thinness of the contact lens packaging and the suppression of lens wrinkles can be balanced, and as a result, the effects of the present invention can be appropriately obtained.

[0069] FIG7 is a schematic cross-sectional view showing the configuration of a contact lens packaging according to another embodiment of the present invention. The contact lens packaging 200C includes: a package 100 having a cover member 10 and a bottom member 20; and a contact lens 120 stored in a storage space 110 sealed by the cover member 10 and the bottom member 20. Although not shown, contact lens preservation solution is also stored in the storage space 110, thereby maintaining the contact lens 120 in a hydrated state.

[0070] As shown in Figures 7 and 8, the cover member 10 has a convex curved surface 12 that is generally circular in plan view and protrudes toward the bottom member 20, and a flat flange portion 14 that surrounds the convex curved surface 12. The bottom member 20 has a concave curved surface 28 that has a plan view shape corresponding to the convex curved surface 12 and protrudes toward the side opposite to the cover member 10; and a flat flange portion 27 that surrounds the concave curved surface 28. The convex curved surface 12 and the concave curved surface 28 overlap.The cover member 10 and the bottom member 20 are configured and joined to form a storage space 110. In the storage space 110, the contact lens 120 is typically configured such that its inner surface is the side of the cover member 10.

[0071] As described above, the storage space 110 is defined by a convex curved surface 12 and a concave curved surface 28. Due to its small volume, even when the storage space has a shape that can store the contact lens in a state that maintains its natural height, the contact lens may adhere to one of the parts and deform during autoclaving, etc., and sometimes feel blurry in the early stages after wearing. Therefore, according to the contact lens packaging described above, the effects of the present invention can be appropriately obtained.

[0072] The contact lens packaging 200C can also be configured such that when the packaging 100 is opened by rolling the cover member 10 upward, the contact lens 120 is attached (adhered) to the cover member 10. There are no particular limitations to this configuration. For example, the concave curved surface 28 may have a smaller radius of curvature than the convex curved surface 12 (e.g., about 13 mm to about 19 mm), and the maximum separation distance between the concave curved surface 28 and the convex curved surface 12 may be less than 7 mm. Alternatively, the contact lens packaging 200C may be configured such that, as per the instructions on pages 6 / 17 of CN 121752940 A, the packaging 100 is opened by rolling the bottom part 20 upwards, and the contact lens 120 is attached (adsorbed) to the cover part 10 (in this case, the cover part 10 functions as the bottom part, and the bottom part 20 functions as the cover part). The volume of the storage space 110 may be, for example, 0.1 mL to 0.6 mL, preferably 0.2 mL to 0.5 mL, and more preferably 0.3 mL to 0.4 mL. Furthermore, the height of the storage space 110 (the maximum value of the separation distance between the convex curved surface and the concave curved surface) can be, for example, 5 mm or less, preferably 1 mm to 3 mm. For details regarding contact lens packaging with such a configuration, please refer to Japanese Patent Publication No. 2023-532254, WO2013 / 153582, etc.

[0073] The contact lens 120 is typically a hydrogel contact lens (so-called soft contact lens). The Young's modulus of the contact lens obtained by a tensile test conducted in an aqueous medium at 35°C is, for example, 1.6 MPa or less, preferably 1.2 MPa or less, 1.0 MPa or less, or 0.8 MPa or less. When the Young's modulus is within the above range, the lens is soft and can suppress congestion and other issues that may occur due to friction between the lens and the surface of the eye. In addition, the Young's modulus of the contact lens is, for example, 0.1 MPa or more, preferably 0.2 MPa or more, and for example, 0.3 MPa or more, 0.4 MPa or more, or 0.5 MPa or more. When the Young's modulus falls within the aforementioned range, it eliminates the inconvenience of wearing lenses due to their excessive softness.Problems (e.g., the lens adheres to the finger or is easily folded, thus requiring adjustment of the lens shape during wear). Furthermore, when the Young's modulus is within the range of the lower to upper limits mentioned above, it is possible to address both the issues related to the lens's softness and the suppression of lens deformation (wrinkling). It should be noted that distilled water, saline solution, etc., are preferably used as the aqueous medium.

[0074] The relaxation modulus of the contact lens obtained by stress relaxation testing in an aqueous medium at 35°C is, for example, 1.8 MPa or less, preferably 1.6 MPa or less, more preferably 1.5 MPa or less, further preferably 1.4 MPa or less, even more preferably 1.3 MPa or less, even more preferably 1.2 MPa or less, even more preferably 1.1 MPa or less, even more preferably 1 MPa or less, and can be 0.9 MPa or less, 0.8 MPa or less, 0.7 MPa or less, 0.6 MPa or less, or 0.5 MPa or less. The relaxation modulus mentioned above can be, for example, 0.1 MPa or more, 0.2 MPa or more, or 0.3 MPa or more. Here, the relaxation modulus of the contact lens is the elastic modulus after 1 second from the start of the measurement when a strain of 75% relative to the upper limit of the linear elastic region in a tensile test is applied to the contact lens in an aqueous medium at 35°C, and the stress required to hold the contact lens is measured. If the relaxation modulus is within the above range, the blurring during the initial wearing of the contact lens after removal from the contact lens packaging can be improved. While not limiting the invention, the reason for this effect is as follows: Since the contact lens is stored in a deformed state (e.g., a flat state) in the storage space, there may be fine deformation (wrinkles) on the surface of the contact lens immediately after removal from the packaging. Such wrinkles can cause uneven power distribution on the contact lens surface, potentially leading to the aforementioned blurring. With contact lenses having the above-mentioned relaxation modulus, the deformation (wrinkles) is easily eliminated over time, and as a result, it is speculated that the blurring during the initial wearing can be quickly eliminated. This effect is more appropriately obtained when using contact lenses with a relaxation modulus of 1.6 MPa or less. For example, when the relaxation modulus is 1.6 MPa or less, even when the loss tangent of the stretching angle described later exceeds 0.1, the initial blurring during wearing can be appropriately eliminated.

[0075] The loss tangent of the stretching angle (tanδ) of the contact lens obtained by dynamic stretching viscoelasticity measurement in an aqueous medium at 35°C is, for example, 0.14 or less, preferably 0.1 or less, more preferably 0.09 or less, further preferably 0.08 or less, even more preferably 0.07 or less, even more preferably 0.06 or less, and can be 0.05 or less or 0.04 or less. The above-mentioned loss tangent (tanδ) can, for example, be 0.001 or more, 0.005 or more, or 0.01 or more. If tanδ is within the above range...Within this range, there is a tendency to suppress wrinkles that occur when a contact lens is stored in a deformed state within the storage space. As a result, it is speculated that blurring during the initial wearing period can be reduced. This effect is more appropriately achieved when using contact lenses with a tanδ of 0.1 or less. For example, when the tanδ is 0.1 or less, blurring during the initial wearing period can be appropriately eliminated even when the relaxation modulus exceeds 1.6 MPa. Specification 7 / 17 pages 10 CN 121752940 A

[0076] In one embodiment, the contact lens has a relaxation modulus of 1.6 MPa or less and a tanδ of 0.1 or less. According to such a contact lens, wrinkles that occur during storage in a deformed state within the storage space can be appropriately suppressed, and the wrinkles that occur can be quickly eliminated after being removed from the packaging. As a result, blurring during the initial wearing period can be more appropriately eliminated.

[0077] The resilience (@100%) of the contact lens obtained by the resilience evaluation test conducted in an aqueous medium at 35°C is, for example, 85% or more, preferably 90% or more, and more preferably 92% to 100%. The above-mentioned resilience (@100%) is the ratio of the energy absorbed when the contact lens is stretched at 100% of its original length to the energy released when it contracts from that stretched state to 0% of its original length. If the resilience (@100%) is within the above range, there is a tendency to suppress the formation of wrinkles in the contact lens stored in the storage space in a deformed state, and as a result, it is presumably possible to reduce blurring during the initial wearing period. Such an effect can be appropriately obtained when using contact lenses with a resilience (@100%) of 90% or more. For example, when the resilience (@100%) is 90% or more, even when the relaxation modulus exceeds 1.7 MPa, blurring during the initial wearing period can be appropriately eliminated.

[0078] The water content of the contact lens is, for example, 10% to 90%, or, for example, 20% to 80%, and can be 30% or more, 35% or more, 40% or more, 45% or more, or 50% or more. If the water content is within the above range, it can function as a hydrogel contact lens with high softness and excellent wearing comfort. In addition, by changing the water content, the relaxation modulus, tanδ, resilience, and other physical properties of the contact lens can be adjusted, resulting in the suppression of wrinkles in the contact lens, and the appropriate elimination of wrinkles. The water content can be measured, for example, by the method described in ISO 18369-4.

[0079] From the viewpoint of balancing the suppression or elimination of deformation (wrinkles) and oxygen permeability, the oxygen permeability coefficient (Dk: ×10-11(cm2 / sec)·(mLO2 / mL·mmHg)) of the contact lens is, for example, 12 or more, preferably 24 or more, more preferably 30 or more, and even more preferably 24 or more.The oxygen permeability coefficient is preferably 36 or higher, more preferably 48 or higher, and even more preferably 60 or higher. For example, it can be 140 or lower, 130 or lower, 120 or lower, 110 or lower, or 100 or lower. The oxygen permeability coefficient is a value calculated according to ISO 18369-4. Furthermore, from the viewpoint of balancing the suppression or elimination of deformation (wrinkles) and oxygen permeability, the oxygen permeability coefficient (oxygen permeability rate) per unit thickness of the contact lens (Dk / t: ×10⁻⁹ (cm·mLO₂ / sec·mL·mmHg)) is, for example, 12 or higher, preferably 24 or higher, more preferably 36 or higher, further preferably 40 or higher, even more preferably 48 or higher, and even more preferably 60 or higher. For example, it can be 170 or lower, 150 or lower, 140 or lower, 130 or lower, 120 or lower, 110 or lower, or 100 or lower. The oxygen permeability rate (Dk / t) of the contact lens can be calculated by dividing the oxygen permeability coefficient (Dk) by the center thickness (cm) of the lens.

[0080] The contact lens is made of an optional suitable polymer material that satisfies the above-mentioned characteristics. The polymer material constituting the contact lens is obtained by polymerizing a polymeric composition containing monomer components, which contains structural units from each monomer in the monomer components. In this specification, the proportion of structural units from each monomer in the polymer material is considered to correspond to the mixing ratio of each monomer in the monomer components.

[0081] The above-mentioned monomer components typically include hydrophilic monomers and crosslinking monomers. The monomer components may further include hydrophobic monomers and / or siloxane monomers as needed. By using monomer components containing siloxane monomers, silicone hydrogel contact lenses can be obtained.

[0082] As hydrophilic monomers, monofunctional monomers with polar groups such as hydroxyl-containing monomers, carboxyl-containing monomers, nitrogen-containing monomers, and alkoxy-containing monomers (except for monomers with siloxane bonds) are preferably used. By including hydrophilic monomers in the monomer components, polymer materials with desired physical properties (softness, relaxation modulus, tanδ, etc.), water content, etc., can be appropriately obtained. The hydrophilic monomer can be used alone or in combination with two or more. The solubility of the hydrophilic monomer in water at 25°C can be, for example, 0.03 g / mL or more.

[0083] As a hydroxyl-containing monomer, alkyl methacrylates containing hydroxyl groups are preferred examples. Specific examples include alkyl methacrylates containing hydroxyl groups and glyceryl methacrylates, such as hydroxymethyl methacrylate, hydroxyethyl methacrylate, hydroxypropyl methacrylate, hydroxybutyl methacrylate, dihydroxyethyl methacrylate, dihydroxypropyl methacrylate, and dihydroxybutyl methacrylate, where the alkyl group has 1 to 4 carbon atoms.

[0084] Examples of carboxyl-containing monomers include (meth)acrylic acid, itaconic acid, maleic acid, fumaric acid, and crotonic acid, and their anhydrides are also preferred.

[0085] Examples of nitrogen-containing monomers include N,N-dimethyl (meth)acrylamide, N-ethyl (meth)acrylamide, N-2-hydroxyethyl (meth)acrylamide, N-isopropyl (meth)acrylamide, etc. (meth)acrylamides, N-vinylpyrrolidone, N-vinylpiperidone, N-vinylcaprolactam, etc. N-vinyl lactams, 1-methyl-3-methylene-2-pyrrolidone, etc. N-methyl lactams, (meth)acrylonitrile, N-(meth)acryloylmorpholine, etc.

[0086] Examples of alkoxy-containing monomers include (meth)acrylic acid alkoxyalkyl esters. Specific examples include methoxymethyl methacrylate, methoxyethyl methacrylate, ethoxymethyl methacrylate, and ethoxyethyl methacrylate, which are alkoxyalkyl esters of (meth)acrylate with 2 to 4 carbon atoms in their alkoxyalkyl groups.

[0087] As a crosslinking monomer, a multifunctional monomer having two or more polymerizable groups (excluding monomers having siloxane bonds) can be used. By including the crosslinking monomer in the monomer composition, polymer materials having the desired physical properties (softness, mechanical strength, relaxation modulus, tanδ, etc.) can be appropriately obtained. Specific examples of crosslinking monomers include butanediol di(meth)acrylate, ethylene glycol di(meth)acrylate, diethylene glycol di(meth)acrylate, triethylene glycol di(meth)acrylate, propylene glycol di(meth)acrylate, dipropylene glycol di(meth)acrylate, diallyl fumarate, allyl (meth)acrylate, vinyl (meth)acrylate, trimethylolpropane tri(meth)acrylate, methacryloyl ethyl (meth)acrylate, divinylbenzene, diallyl phthalate, diallyl adipate, triallyl diisocyanate, α-methylene-N-vinylpyrrolidone, and (meth)propyl Examples of suitable monomers include 4-vinylbenzyl acrylate, 3-vinylbenzyl (meth)acrylate, 2,2-bis((meth)acryloyloxyphenyl)hexafluoropropane, 1,4-bis(2-(meth)acryloyloxyhexafluoroisopropyl)benzene, 1,3-bis(2-(meth)acryloyloxyhexafluoroisopropyl)benzene, 1,2-bis(2-(meth)acryloyloxyhexafluoroisopropyl)benzene, 1,4-bis(2-(meth)acryloyloxyisopropyl)benzene, 1,3-bis(2-(meth)acryloyloxyisopropyl)benzene, and 1,2-bis(2-(meth)acryloyloxyisopropyl)benzene. Among these, butanediol di(meth)acrylate and ethylene glycol di(meth)acrylate are preferred due to their excellent copolymerization properties and the ease with which the flexibility and mechanical strength of the polymer material can be adjusted. Crosslinking monomers can be...Only one type can be used, or two or more types can be used in combination.

[0088] As a hydrophobic monomer, monofunctional monomers without polar groups, such as alkyl (meth)acrylates, fluorinated alkyl (meth)acrylates, aromatic ring (meth)acrylates, and styrene monomers, can preferably be used (except for monomers with siloxane bonds). By including a hydrophobic monomer in the monomer component, polymer materials with desired mechanical strength, water content, etc., can be appropriately obtained. Only one type of hydrophobic monomer can be used, or two or more types can be used in combination. The solubility of the hydrophobic monomer in water at 25°C can, for example, be less than 0.03 g / mL.

[0089] As an alkyl (meth)acrylate, alkyl (meth)acrylates with 1 to 20 carbon atoms in the alkyl group are preferably examples. Specific examples include methyl methacrylate, ethyl methacrylate, propyl methacrylate, butyl methacrylate, pentyl methacrylate, hexyl methacrylate, heptyl methacrylate, nonyl methacrylate, stearyl methacrylate, octyl methacrylate, decyl methacrylate, lauryl methacrylate, pentadecyl methacrylate, 2-ethylhexyl methacrylate, cyclopentyl methacrylate, and cyclohexyl methacrylate, which are linear, branched, or cyclic alkyl methacrylates. Alkyl methacrylates with 1 to 5 carbon atoms in the alkyl group are preferred. It should be noted that methyl acrylate has a solubility in water at 25°C exceeding 0.03 g / mL, but because it lacks polar groups, it is treated as a hydrophobic monomer in this specification.

[0090] Examples of fluorinated (meth)acrylates include substances in which fluorine is introduced into the alkyl group of the above-mentioned (meth)acrylates. Specifically, examples include 2,2,2-trifluoroethyl methacrylate, 2,2,3,3-tetrafluoropropyl methacrylate, 2,2,3,3-tetrafluoro-tert-amyl methacrylate, 2,2,3,4,4,4-hexafluorobutyl methacrylate, 2,2,3,4,4,4-hexafluoro-tert-hexyl methacrylate, 2,3,4,5,5,5-hexafluoro-2,4-bis(trifluoromethyl)amyl methacrylate, 2,2,3,3,4,4-hexafluorobutyl methacrylate, 2,2,2,2',2',2'-hexafluoroisopropyl methacrylate, 2,2,3,3,4,4,4-heptafluorobutyl methacrylate, and 2,2,3,3,4,4,5,5-octafluoroamyl methacrylate.

[0091] Examples of aromatic ring-containing (meth)acrylates include phenoxyethyl (meth)acrylate and (meth)propylene.Examples of styrene monomers include ethyl phenyl acrylate, benzyl methacrylate, phenyl methacrylate, and pentabromophenyl methacrylate.

[0092] Examples of styrene monomers include styrene, α-methylstyrene, methylstyrene, ethylstyrene, acetoxystyrene, methoxystyrene, ethoxystyrene, propoxystyrene, and butoxystyrene.

[0093] Examples of siloxane monomers include any suitable monomer as long as it has a siloxane bond (Si-O-Si) and a polymerizable group. By including a siloxane monomer in the monomer composition, a polymer material with high oxygen permeability can be appropriately obtained. The number of siloxane bonds in the siloxane monomer is, for example, 1 to 100, and can be 2 to 20, 2 to 10, or 2 to 5. The number of siloxane bonds mentioned above is not the number of repetitions of siloxane bonds in one chain, but refers to the total number of all siloxane bonds in the monomer molecule. The number of polymerizable groups in the siloxane monomer can be one or more. A single siloxane monomer can be used alone, or two or more can be used in combination.

[0094] Examples of siloxane monomers that have been used in ophthalmic devices include those described in paragraphs 0039 to 0044 of Japanese Patent Application Publication No. 2015-503631, those described in paragraphs 0060 to 0065 of Japanese Patent Application Publication No. 2014-40598, and those described in paragraphs 0024 to 0037 of WO2015 / 92858.

[0095] Other specific examples of siloxane monomers include trimethylsiloxydimethylsilyl methyl methacrylate, trimethylsiloxydimethylsilyl propyl methacrylate, methylbis(trimethylsiloxy)silyl propyl methacrylate, tri(trimethylsiloxy)silyl propyl methacrylate, mono[methylbis(trimethylsiloxy)siloxy]bis(trimethylsiloxy)silyl propyl methacrylate, tri[methylbis(trimethylsiloxy)siloxy]silyl propyl methacrylate, methylbis(trimethylsiloxy)silyl propyl glycerol methacrylate, tri(trimethylsiloxy)silyl propyl glycerol methacrylate, and mono[methylbis(trimethylsiloxy)siloxy]silyl propyl methacrylate. Bis(trimethylsiloxy)silylpropylglyceride, (meth)acrylate trimethylsilylethyltetramethyldimethoxypropylglyceride, (meth)acrylate trimethylsilylmethyl methyl ester, (meth)acrylate trimethylsilylpropyl glyceride, (meth)acrylate trimethylsilylpropyl ester, (meth)acrylate trimethylsilyloxydimethylsilylpropyl glyceride, (meth)acrylate methylbis(trimethylsiloxy)silylethyltetramethyldimethoxypropyl glyceride, (meth)acrylate methylbis(trimethylsiloxy)silylethyltetramethyldimethoxypropyl esterAlkyl methacrylates containing siloxanes, such as tetramethyltriisopropylcyclotetrasiloxane propyl acrylate and tetramethyltriisopropylcyclotetramethoxybis(trimethylsiloxane)siloxane propyl acrylate; alkyl styrene containing tri(trimethylsiloxane)siloxane, bis(trimethylsiloxane)methylsiloxane, trimethylsiloxane dimethylsiloxane, tri(trimethylsiloxane)siloxane dimethylsiloxane, [bis(trimethylsiloxane)methylsiloxane]dimethylsiloxane, (trimethylsiloxane)dimethylsiloxane, heptamethyltrisiloxane, nonamethyltetrasiloxane, decamethylheptamethylsiloxane, heptamyldecyl styrene, hexamethyldecyl styrene, heptamyldecyl styrene, heptamyldecyl styrene, heptamyldecyl styrene, heptamyldecyl styrene, heptamyldecyl styrene, heptamyldecyl styrene, heptamyldecyl styrene, heptamyldecyl styrene, heptamyldecyl styrene, heptamyldecyl styrene, heptamyldecyl styrene, heptamyldecyl styrene, 10 / 17 pages, 13 CN 121752940 A Oxyalkylstyrene, hexamethyldecylsiloxanestyrene, trimethylsiloxypentamethyldimethsiloxymethylsilylstyrene, tri(pentamethyldimethsiloxy)silylstyrene, tri(trimethylsiloxy)siloxybis(trimethylsiloxy)silylstyrene, bis(heptamethyltrimethsiloxy)methylsilylstyrene, tri[methylbis(trimethylsiloxy)siloxy]silylstyrene, hepta(trimethylsiloxy)trimethylstyrene, trimethylsiloxybis[tri(trimethylsiloxy)siloxy]silylstyrene, nonamethyltetramethylsiloxyundecylmethylpentamethylsiloxymethylsilylstyrene, tri[tri(trimethylsiloxy)siloxy]silylstyrene, (tri(trimethylsiloxyhexamethyl))tetramethyl Styrene derivatives containing siloxanes include siloxane-based derivatives such as tris(trimethylsiloxane)siloxane]trimethylsiloxane-silyl styrene, nona(trimethylsiloxane)tetrasilyl styrene, bis(decamethylhexamethylsiloxane)methylsilyl styrene, heptamethylcyclotetrasiloxane styrene, heptamethylcyclotetrasiloxane bis(trimethylsiloxane)silyl styrene, tripropyltetramethylcyclotetrasiloxane styrene, and trimethylsilyl styrene; and fumarate diesters containing siloxanes such as bis(3-(trimethylsilyl)propyl) fumarate, bis(3-(pentamethyldisiloxane)propyl) fumarate, and bis(tris(trimethylsiloxane)silylpropyl) fumarate. Among these, styrene derivatives containing siloxanes are preferred from the perspective of easily balancing high oxygen permeability and hardness.

[0096] As another specific example of a siloxane monomer, examples include mono(meth)acryloyloxypropyl-terminated mono-n-butyl-terminated polydimethylsiloxane, mono(meth)acryloyloxypropyl-terminated mono-n-methyl-terminated polydimethylsiloxane, and mono(meth)acryloyloxypropyl-terminated mono-n-methyl-terminated polydimethylsiloxane.The monomers include (meth)acryloyloxypropyl-terminated mono-n-butyl-terminated polydiethylsiloxane, mono(meth)acryloyloxypropyl-terminated mono-n-methyl-terminated polydiethylsiloxane, mono(meth)acryloylaminopropyl-terminated mono-n-butyl-terminated polydimethylsiloxane, mono(meth)acryloylaminopropyl-terminated mono-n-methyl-terminated polydimethylsiloxane, mono(meth)acryloylaminopropyl-terminated mono-n-butyl-terminated polydiethylsiloxane, mono(meth)acryloylaminopropyl-terminated mono-n-methyl-terminated polydiethylsiloxane, etc. In these siloxane monomers, the number of (Si-O) repetitions can be, for example, 4 to 20, preferably 4 to 12, more preferably 4 to 10.

[0097] The mixing ratio of hydrophilic monomers in the monomer components other than crosslinking monomers is, for example, 30% by weight or more, 40% by weight or more, preferably 50% by weight or more, more preferably 60% by weight or more, for example, 100% by weight or less, and also, for example, 95% by weight or less, 90% by weight or less.

[0098] The mixing ratio of hydrophobic monomers in the monomer components other than crosslinking monomers is, for example, 5% by weight or less, preferably 3% by weight or less, and can be 0% by weight to 1% by weight.

[0099] The mixing ratio of siloxane monomers in the monomer components other than crosslinking monomers is, for example, 60% by weight or less, preferably 50% by weight or less, more preferably 40% by weight or less, and can be 30% by weight or less, 20% by weight or less, or 15% by weight or less. In addition, the lower limit of the mixing ratio of the above-mentioned siloxane monomers can be 0% by weight or more, 3% by weight or more, or 5% by weight or more.

[0100] The mixing ratio of crosslinking monomers in the monomer components is, for example, 0.05% by weight or more, and also, for example, 0.1% by weight or more, typically 10% by weight or less, for example, 3% by weight or less, preferably 1% by weight or less, and more preferably 0.8% by weight or less.

[0101] By changing the types and / or mixing ratios of the aforementioned monomers, the mechanical strength, water content, relaxation modulus, tanδ, resilience, and other physical properties of the contact lens can be adjusted. The physical properties of the resulting polymer can vary depending on the type of monomer, etc., but by increasing the mixing ratio of hydrophilic monomers and decreasing the mixing ratio of hydrophobic monomers, contact lenses with mechanical strength, water content, relaxation modulus, tanδ, resilience, and other physical properties within the aforementioned desired range can be appropriately obtained. For example, by increasing the mixing ratio of hydrophilic monomers and / or decreasing the mixing ratio of hydrophobic monomers, mechanical strength, relaxation modulus, and tanδ can be reduced, while water content and resilience can be increased. In addition, if the mixing ratio of siloxane monomers is high, oxygen permeability can be improved; on the other hand, it is observed that the deformation tends to remain as wrinkles in deformed contact lenses. Therefore, byBy including siloxane monomers in the above-mentioned mixing ratio, it is possible to achieve the desired relaxation modulus, tanδ, resilience, etc., while ensuring preferred oxygen permeability, thereby suppressing the formation of wrinkles or quickly eliminating wrinkles. As a result, it is possible to obtain contact lens packaging with excellent wearing comfort and improved blurring in the initial wearing stage.

[0102] The monomer component may further include functional monomers. Examples of functional monomers include polymerizable ultraviolet absorbers, polymerizable pigments, and polymerizable ultraviolet absorbing pigments. For specific examples, refer to

[0087] to

[0089] of WO2022 / 044117. In addition, various functional monomers are commercially available, and appropriate selection can be made from them according to the purpose. It should be noted that functional monomers are monomers that impart a specified function to the obtained polymer and are not included in the above-mentioned hydrophobic monomers, hydrophilic monomers, crosslinking monomers, and siloxane monomers.

[0103] The total mixing ratio of the functional monomers in the monomer components is, for example, 5% by weight or less, preferably 0.0001% by weight to 5% by weight, more preferably 0.05% by weight to 3% by weight.

[0104] The polymerizable composition typically contains a polymerization initiator in addition to the monomer components described above, and may further contain solvents and / or additives as needed. Examples of additives include cooling agents, thickeners, surfactants, non-polymerizable pigments, and non-polymerizable ultraviolet absorbers.

[0105] The mixing amount of the above-mentioned additives in the polymerizable composition may be, for example, 0.01% by weight to 5% by weight, preferably 0.01% by weight to 3% by weight, relative to 100 parts by weight of the monomer components.

[0106] As a polymerization method, photopolymerization, thermal polymerization, and combinations thereof can be applied.

[0107] In the case of polymerizing the polymerizable composition by photopolymerization, it is preferable to fill or coat the mold with the polymerizable composition and then irradiate the mold with light (e.g., ultraviolet light). Specifically, contact lenses can be manufactured using any manufacturing method such as die casting or spin casting. The material of the mold used in photopolymerization is not particularly limited as long as it is a material that can transmit the light required for polymerization. The wavelength of the light irradiating the polymeric composition within the mold is appropriately set according to the type of photopolymerization initiator used. Furthermore, the illuminance and irradiation time can be appropriately set according to the composition of the polymeric composition.

[0108] In the case of polymerizing the polymeric composition by thermal polymerization, it is preferable to slowly heat the mold after filling or coating it with the polymeric composition. The heating temperature and heating time when heating the polymeric composition within the mold can be appropriately set according to the composition of the polymeric composition.

[0109] After polymerization, contact lenses can be obtained by removing the polymer material from the mold. If necessary, the obtained contact lenses can be immersed in water, an organic solvent, or a mixture thereof to remove unreacted monomer components and solvents.The residue is dissolved. The residue dissolution process can be repeated. Alternatively, the obtained contact lenses can be subjected to surface treatments such as plasma treatment.

[0110] As described above, the contact lens packaging can be obtained by joining the cover part and the base part at least in a specified area surrounding the contact lens while the contact lens is positioned in a specified position on the base part (e.g., on the lens loading part or the storage recess). The joining of the cover part and the base part can be performed, for example, by heat sealing or ultrasonic sealing. The contact lens packaging can be sterilized as needed. Sterilization can be performed by any suitable method such as pressure sterilization (e.g., high-temperature steam sterilization), gamma ray sterilization, etc.

[0111] [Methods to improve the recovery of wrinkles and methods to suppress the generation of wrinkles]

[0112] As described above, according to the contact lens with the low relaxation modulus, when the contact lens is deformed (wrinkled) due to being stored in a sealed storage space in a deformed state, the wrinkles are easily eliminated over time after opening, thus quickly eliminating the blurring at the beginning of wearing. Therefore, according to another aspect of the present invention, a method is provided to improve the resilience of contact lenses when the contact lens packaging is opened, as described on pages 12 / 17 of the specification, CN 121752940 A. The method includes: forming a contact lens packaging by joining opposing cap and bottom parts in such a way as to form a storage space in which the contact lens is disposed in a sealed state, wherein the height of the storage space is less than the natural sag of the contact lens, and the relaxation modulus of the contact lens is 1.6 MPa or less.

[0113] As described above, with the contact lens having a small tanδ or high resilience, it is possible to suppress the formation of wrinkles during storage in a deformed state within the sealed storage space, thereby reducing blurring during the initial wearing period. Therefore, according to another aspect of the present invention, a method is provided to suppress wrinkling of contact lenses in a contact lens package, wherein the method comprises: joining opposing cover and bottom parts to form a storage space in which a contact lens is disposed in a sealed state to manufacture a contact lens package, the height of the storage space being less than the natural sag of the contact lens, the method satisfying at least one of (i) and (ii) below: (i) the loss tangent of the stretching of the contact lens, as determined by dynamic tensile viscoelasticity measurement in an aqueous medium at 35°C, is 0.1 or less; (ii) the proportion of energy released to shrink from the stretched state to a state of 0% stretching ratio relative to the energy absorbed when the contact lens is stretched at 100% stretching ratio in an aqueous medium at 35°C is 90% or more.

[0114] Examples

[0115] Hereinafter, the present invention will be specifically described by way of examples, but the present invention is not limited to these examples.It should be noted that, unless otherwise specified, “parts” and “%” in the examples and comparative examples are based on weight.

[0116] [Experimental Examples 1-7]

[0117] A cover component and a bottom component as shown in Figures 1A to 1D were prepared. Specifically, the cover component was made of a flexible aluminum vapor-deposited PP film. The bottom component was made of a support substrate and a lens loading substrate. The support substrate was made of a flexible aluminum vapor-deposited PP film, and the lens loading substrate was fixed to the aluminum vapor-deposited surface by an adhesive. The lens loading substrate was made of PP and had a circular plate-shaped lens loading portion with through holes and an edge portion formed on its outer periphery.

[0118] As contact lenses, contact lenses obtained by polymerizing the monomer components shown in Table 1 were used.

[0119] After adding 1 drop of physiological saline to the lens loading portion of the support substrate with a dropper, various contact lenses were placed on it with the inner surface facing down, and another 1 drop of physiological saline was added on it with a dropper.

[0120] Next, the cover component is placed over the lens loading substrate and the contact lens, and the outer periphery of the lens loading substrate is heat-sealed while the outer edge of the cover component is aligned with the outer edge of the bottom component. This results in a contact lens package containing the contact lens in a flattened state within the storage space between the cover component and the bottom component. The upper surface of the contact lens package is flat, and the height of the storage space is 1 mm.

[0121] Next, the contact lens package is pressure-sterilized using a small autoclave. The sterilization temperature is 121°C, the sterilization pressure is 0.20 MPa, and the sterilization time is 20 minutes.

[0122] In Table 1, the center thickness of the contact lens is the average of the center thicknesses of three contact lenses in a hydrated state.

[0123] [Evaluation of the physical properties of the contact lens]

[0124] <Preparation of the test sample>

[0125] The contact lens is removed from the pressure-sterilized contact lens package and cut using a processing fixture with four blades arranged in parallel at 2 mm intervals. Thus, as shown in Figure 9, three elongated contact lens pieces were made from one contact lens. Using the contact lens piece passing through the center of the lens (C in Figure 9) as the test specimen, tensile tests, dynamic tensile viscoelasticity tests, resilience evaluation tests, and oxygen permeability coefficient (Dk value) measurements were performed. Using the peripheral portion of the contact lens piece (S1 or S2 in Figure 9) as the test specimen, stress relaxation tests were performed.

[0126] <Tensile Test> Specification 13 / 17 pages 16 CN 121752940 A

[0127] In the tensile test of stretching the test specimen at a certain speed, the stress-strain curve was obtained from the original data of the stretching distance vs. the detection load. The Young's modulus was calculated from the initial slope (strain range = 0–10%) in the stress-strain curve, and the average value for n=3 was obtained. The test conditions are as follows.

[0128] • Measuring equipment: Viscoelasticity measuring device "RSA3" (manufactured by TA Instruments)

[0129] • Measuring environment: Distilled water at 35°C (physiological saline at 35°C for Experiments 1 and 2)

[0130] • Number of test samples: n=3

[0131] • Measuring mode: Transient

[0132] • Measurement item name: Multiple Extension Mode Test

[0133] • Tensile speed: 0.01mm / sec, 140 seconds (140 data points were obtained, 1.4mm of stretch)

[0134] • Young's modulus calculation: Strain range 0~10%

[0135] <Stress relaxation test>

[0136] A strain (initial strain) of 75% relative to the upper limit of the linear elastic region in the above tensile test was applied to the test sample, and the change in stress (relaxation) required to maintain the test sample with the initial strain was measured. Calculate the elastic modulus (stress / strain) after 1 second from the start of the measurement as the relaxation modulus (MPa), and obtain the average value for n=3. The measurement conditions are as follows.

[0137] • Measuring equipment: Viscoelasticity measuring device "RSA3" (manufactured by TA Instruments)

[0138] • Measuring environment: Distilled water at 35°C (physiological saline at 35°C for Experiments 1 and 2)

[0139] • Number of samples: n=3

[0140] • Measuring mode: Transient

[0141] • Measuring item name: Stress relaxation

[0142] • Initial strain: Strain relative to 75% of the upper limit of the linear elastic region in the above tensile test

[0143] <Dynamic tensile viscoelasticity test>

[0144] Based on the response of the test sample under a tensile state while maintaining a certain load, the elastic component (E') and viscous component (E”) of the sample were calculated. Then, the tensile loss tangent (tanδ) was calculated from E” / E' at 1.0 Hz, and the average value of n=3 was obtained. The measurement conditions are as follows.

[0145] • Measuring equipment: Viscoelasticity measuring device "RSA3" (manufactured by TA Instruments)

[0146] • Measuring environment: Distilled water at 35°C (physiological saline at 35°C for Experiments 1 and 2)

[0147] • Number of samples measured: n=3

[0148] • Measuring mode: Dynamic

[0149] • Measuring item name: Dynamic Frequency Sweep Test

[0150] • Measuring frequency: 0.628 rad / sec (=0.1 Hz)~62.8 rad / sec (=10 Hz)

[0151] • Initial Static Force: The load equivalent to 75% of the linear elastic region is calculated from Young's modulus and the cross-sectional area of ​​the specimen.

[0152] • Dynamic Strain: 2.5%

[0153] <Resilience Evaluation Test>

[0154] The specimen is stretched at a certain tensile speed, and then, while applying different stretching ratios, the tensile shrinkage is repeatedly measured to shrink back to the original size, and stress-strain curves based on multiple stretching ratios are obtained. The measurement conditions are as follows.

[0155] The resilience is calculated according to [Formula: Resilience (%) = Area under the "stress-strain curve" during the shrinkage process ÷ Area under the "stress-strain curve" during the stretching process × 100], and the average value of the resilience at a stretching ratio of 100% is obtained (n=3). Instruction manual, pages 14 / 17, CN 121752940 A

[0156] · Measuring equipment: Viscoelasticity measuring device "RSA3" (manufactured by TA Instruments)

[0157] · Measuring environment: Distilled water at 35°C (physiological saline at 35°C for Experiments 1 and 2)

[0158] · Number of samples: n=3

[0159] · Measuring mode: Transient

[0160] · Measurement item name: Multiple Extension Mode Test

[0161] · Tensile speed: 0.1mm / sec

[0162] · Tensile ratio: Approximately 25%→50%→75%→100%→125%→150% (end)

[0163] <Determination of oxygen permeability coefficient (Dk value)>

[0164] The oxygen permeability coefficient was calculated according to ISO 18369-4.

[0165] <Determination of Moisture Content>

[0166] Moisture content was determined according to ISO 18369-4.

[0167] [Evaluation Test of Power Distribution]

[0168] For contact lenses taken from the contact lens packaging prepared in the experimental example, the Q values ​​were measured 15 seconds and 900 seconds after opening under the following test conditions, and the average value of n=3 was obtained. The Q value is a quality coefficient proportional to the amount of wavefront distortion in the power unit of the lens's resolution area, and is a value representing the standard deviation of the power distribution in that area. A small Q value means that the power unevenness on the lens surface is small. For example, Figure 10(a) shows the power distribution of contact lenses with a Q value of 2 or higher in all ring areas, and (b) shows the power distribution of contact lenses with a Q value of 2 or lower in all ring areas. It can be seen that the power unevenness of the contact lenses in (b) is smaller than that of the contact lenses in (a).

[0169] • Measuring equipment: Underwater power meter "VC-2001" (manufactured by Visionics)

[0170] • Measuring temperature: Approximately 20-25℃ (adjustable to indoor temperature)

[0171] • Environmental solution (solution used to soak the lens during measurement): Phosphate-buffered saline

[0172] • Analytical area: A ring area with a radius of 1.5 mm to 5.0 mm from the center of the lens when viewed from above (specifically, a ring area with a radius of 1.5 mm to 2.0 mm, a ring area with a radius of 2.0 mm to 2.5 mm, a ring area with a radius of 2.5 mm to 3.0 mm, a ring area with a radius of 3.0 mm to 4.0 mm, and a ring area with a radius of 4.0 mm to 5.0 mm)

[0173] • Number of lenses tested: 3 lenses / sample

[0174] [Table 1] Instruction manual 15 / 17 pages 18 CN 121752940 A

[0175] As shown in Table 1, for contact lenses with a tanδ of 0.1 or less, a Q value of 2 or less was achieved in a ring area with a radius of 1.5 mm to 2.5 mm after 15 seconds of removal from the thin packaging (Experimental Examples 1-3 and 5). Among them, the contact lenses of Experimental Examples 3 and 5, which were prepared using siloxane monomers, had a ring region where the Q value after 15 seconds exceeded 1, but the contact lenses of Experimental Examples 1 and 2, which were not prepared using siloxane monomers, had a Q value of less than 1 after 15 seconds in all ring regions.

[0176] In addition, for contact lenses with a relaxation modulus of less than 1.6 MPa after 1 second, even when tanδ exceeded 0.1, a Q value of less than 2 was achieved in a ring region with a radius of 1.5 mm to 2.5 mm after 900 seconds of removal from the thin package, and a Q value of less than 3 was achieved in the entire ring region with a radius of 1.5 mm to 5.0 mm (Experimental Example 4).

[0177] As can be seen from the above, by storing contact lenses with a small tanδ (e.g., tanδ≦0.1) in a thin package, it is possible to suppress the formation of wrinkles (deformation) of contact lenses during storage. Furthermore, it is known that by storing contact lenses with low relaxation modulus (e.g., relaxation modulus ≤ 1.6 MPa) in thin packaging, the elimination (recovery) of wrinkles (deformation) of the contact lenses after opening can be improved.

[0178] Furthermore, as shown in the table below, contact lenses with low relaxation modulus (e.g., relaxation modulus of 1.6 MPa or less or 1.3 MPa or less) tend to have a large recovery rate of wrinkles [Q value reduction rate = (Q value after 1-900 seconds / Q value after 15 seconds) × 100] between 15 seconds and 900 seconds. In addition, it is known that contact lenses with high resilience (e.g., resilience ≥ 90%) can suppress the formation of wrinkles (deformation) of contact lenses during storage.

[0179] [Table 2]

[0180] [Experimental Examples 8-10]

[0181] Contact lens packaging was prepared in the same manner as in Experimental Examples 1-7 above, using contact lenses made by polymerizing the polymeric composition of the following composition. Regarding the received contact lens packaging, the dot area within 3mm from the center of the lens when viewed from above.The domain was used as the measurement area. In addition, the power distribution was evaluated in the same way as in Experimental Examples 1-7. The results showed low Q values, similar to those in Experimental Examples 1-3, on pages 16 / 17 of the specification, CN 121752940 A. It can be seen that, according to the contact lens packaging of Experimental Examples 8-10, by improving the elimination (restoration) of wrinkles (deformation) of contact lenses after opening, or by suppressing the formation of wrinkles (deformation) of contact lenses during storage, even when contact lenses are taken out of the thin packaging and worn immediately, the initial blurring after wearing can be improved.

[0182] [Table 3]

[0183] Industrial Applicability

[0184] The contact lens packaging of the embodiments of the present invention can be appropriately used for the manufacture and sale of contact lenses.

[0185] Symbol Explanation

[0186] 10 Cover component

[0187] 20 Bottom component

[0188] 22 Support substrate

[0189] 24 Lens mounting substrate

[0190] 100 Packaging

[0191] 110 Storage space

[0192] 120 Contact lens

[0193] 200 Contact lens packaging instructions 17 / 17 pages 20 CN 121752940 A Figure 1A Figure 1B Figure 1C Instruction manual drawings 1 / 6 pages 21 CN 121752940 A Figure 1D Instruction manual drawings 2 / 6 pages 22 CN 121752940 A Figure 2 Figure 3 Instruction manual drawings 3 / 6 pages 23 CN 121752940 A Figure 4A Figure 4B Figure 5 Figure 6 Instruction manual drawings 4 / 6 pages 24 CN 121752940 A Figure 7 Figure 8 Figure 9. Appendix to the instruction manual, page 5 / 6, 25 CN 121752940 A Figure 10. Appendix to the instruction manual, page 6 / 6, 26 CN 121752940 A

Claims

1. A contact lens packaging comprising: a package having a cap and a bottom part; and a contact lens, which is housed in a deformable state within a storage space sealed by the cap and the bottom part. The relaxation modulus of the contact lens is below 1.6 MPa. The relaxation modulus of the contact lens is the elastic modulus after 1 second from the start of the measurement when the contact lens is subjected to a strain of 75% relative to the upper limit of the linear elastic region in the tensile test in an aqueous medium at 35°C.

2. The contact lens packaging according to claim 1, wherein, The loss tangent of the contact lens, determined by dynamic tensile viscoelasticity measurement in an aqueous medium at 35°C, is less than 0.

14.

3. The contact lens packaging according to claim 1, wherein, The relaxation modulus of the contact lens is below 1.3 MPa.

4. A contact lens packaging comprising: a package having a cap and a bottom part; and a contact lens, which is housed in a deformable state in a storage space sealed by the cap and the bottom part. The loss tangent of the contact lens, determined by dynamic tensile viscoelasticity measurement in an aqueous medium at 35°C, is less than 0.

1.

5. The contact lens packaging according to claim 4, wherein, The stretch loss tangent of the contact lens is less than 0.

06.

6. The contact lens packaging according to claim 4, wherein, The relaxation modulus of the contact lens is below 1.8 MPa. The relaxation modulus of the contact lens is the elastic modulus after 1 second from the start of the measurement when the contact lens is subjected to a strain of 75% relative to the upper limit of the linear elastic region in the tensile test in an aqueous medium at 35°C.

7. A contact lens packaging comprising: a package having a cap and a bottom part; and a contact lens, which is housed in a deformable state within a storage space sealed by the cap and the bottom part. The loss tangent of the contact lens, determined by dynamic tensile viscoelasticity measurement in an aqueous medium at 35°C, is below 0.

1. The relaxation modulus of the contact lens is below 1.6 MPa. The relaxation modulus of the contact lens is the elastic modulus after 1 second from the start of the measurement when the contact lens is subjected to a strain of 75% relative to the upper limit of the linear elastic region in the tensile test in an aqueous medium at 35°C.

8. The contact lens packaging according to claim 7, wherein, The stretch loss tangent of the contact lens is less than 0.

06.

9. The contact lens packaging according to claim 7, wherein, The relaxation modulus of the contact lens is below 1.2 MPa.

10. The contact lens packaging according to claim 1, 4, or 7, wherein, The oxygen permeability (Dk / t) of the contact lens is above 24.

11. The contact lens packaging according to claim 1, 4, or 7, wherein, The contact lens is a silicone hydrogel lens.

12. The contact lens packaging according to claim 1, 4, or 7, wherein, The contact lens is stored in the storage space with its height less than its natural sagittal height.

13. The contact lens packaging according to claim 1, 4, or 7, wherein, The height of the storage space is less than 2mm.

14. A method for improving the resilience of contact lenses to wrinkles when the contact lens packaging is opened, comprising: Contact lens packaging is made by joining opposing cover and bottom components to form a sealed storage space in which the contact lens is placed. The height of the storage space is less than the natural sagittal height of the contact lens. The relaxation modulus of the contact lens is below 1.6 MPa. The relaxation modulus of the contact lens is the elastic modulus after 1 second from the start of the measurement when the contact lens is subjected to a strain of 75% relative to the upper limit of the linear elastic region in the tensile test in an aqueous medium at 35°C.

15. A method for preventing wrinkles in contact lenses within a contact lens package, comprising: Contact lens packaging is made by joining opposing cover and bottom components to form a sealed storage space in which the contact lens is placed. The height of the storage space is less than the natural sagittal height of the contact lens. The method satisfies at least one of the following (i) and (ii): (i) The loss tangent of the contact lens obtained by dynamic tensile viscoelasticity measurement in an aqueous medium at 35°C is less than 0.1; (ii) The proportion of energy released to shrink from the stretched state to 0% of the stretch ratio when the contact lens is stretched to 100% in an aqueous medium at 35°C is more than 90% relative to the energy absorbed.

16. A contact lens package comprising: a package having a cap portion and a bottom portion; and a contact lens housed in a storage space sealed by said cap portion and said bottom portion. The storage space is defined by the convex curved surface of the cover component protruding towards the bottom component and the concave curved surface of the bottom component protruding towards the side opposite to the cover component. The contact lens is configured such that when the packaging is opened, it adheres to the cover component or the bottom component. The contact lens packaging satisfies at least one of the following (i) and (ii): (i) The relaxation modulus of the contact lens is 1.6 MPa or less. The relaxation modulus of the contact lens is the elastic modulus after 1 second from the start of the measurement when the contact lens is subjected to a strain of 75% relative to the upper limit of the linear elastic region in the tensile test in an aqueous medium at 35°C. (ii) The loss tangent of the contact lens obtained by dynamic tensile viscoelasticity measurement in an aqueous medium at 35°C is less than 0.1.

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