Tumor electric field therapy system

Abstract

The invention provides a tumor electric field treatment system. The tumor electric field treatment system comprises an electrode plate and an electric field generator or an adapter electrically connected with the electrode plate. The electrode plate is provided with a flexible circuit board, a plurality of electrode units and a handshake chip, each electrode unit comprises a dielectric element and a temperature sensor with a signal end and a grounding end, the plurality of electrode units are divided into a plurality of rows and columns on a circuit, the grounding ends of the temperature sensors in the same row are short-circuited through the same path of grounding wire on the flexible circuit board, and the handshake chip is connected with the dielectric element. The signal ends of the temperature sensors in the same column are in short circuit through the same dual-purpose signal line on the flexible circuit board, and each dual-purpose signal line transmits an alternating current signal to each dielectric element in a first mode and transmits a direct current signal to each temperature sensor in a second mode. The grounding wires are in a disconnected state in the first mode and are sequentially and independently connected in the second mode. The adapter or the electric field generator provides an alternating current signal or a direct current signal for the electrode plates through the dual-purpose signal lines.

Description

(19) State Intellectual Property Office (12) Invention Patent Application (10) Application Publication Number (43) Application Publication Date (21) Application Number 202511460397.7 (22) Application Date 2024.10.25 (66) Domestic Priority Data 202311809226.1 2023.12.26 CN PCT / CN2023 / 142515 2023.12.27 CN (62) Divisional Application Data 202411499210.X 2024.10.25 (71) Applicant Jiangsu Hailai Xinchuang Medical Technology Co., Ltd. Address 214100, Jiangsu Province, Wuxi City, Huishan Economic Development Zone, Huishan Avenue, No. 1699, Building 7, 7th Floor, Area A and Area B Applicant: Hangzhou Hailai Xinchuang Medical Technology Co., Ltd. (72) Inventor: Ying Jianjun, Yu Jing, Shen Qichao, Hui Jiajie, Zhang Jun Request: Name not to be disclosed Hu Tao (51) Int.Cl. A61N 1 / 36 (2006.01) A61N 1 / 04 (2006.01) G01K 13 / 00 (2021.01) (54) Invention title: Tumor electric field therapy system (57) Abstract: This application provides a tumor electric field therapy system, including electrode sheets and an electric field generator or adapter electrically connected to the electrode sheets. The electrode sheet comprises a flexible circuit board, several electrode units, and a handshake chip. Each electrode unit includes a dielectric element and a temperature sensor with both a signal terminal and a ground terminal. Multiple electrode units are grouped into multiple rows and columns. The ground terminals of temperature sensors in the same row are short-circuited via a common grounding line on the flexible circuit board. The signal terminals of temperature sensors in the same column are short-circuited via a common dual-purpose signal line on the flexible circuit board. Each dual-purpose signal line transmits AC signals to the dielectric elements in a first mode and DC signals to the temperature sensors in a second mode. Each grounding line is disconnected in the first mode and sequentially and individually turned on in the second mode. An adapter or electric field generator provides AC or DC signals to the electrode sheet via each dual-purpose signal line. Claims (2 pages), Description (34 pages), Drawings (13 pages), CN 120983809 A, 2025.11.21, CN 1 20 98 38 09 A. 1. A tumor electric field therapy system, characterized in that it comprises: an electrode sheet, the electrode sheet having a flexible circuit board, a plurality of electrode units disposed on the flexible circuit board, and a handshake chip, the electrode unit including a dielectric element and a temperature sensor having a signal terminal and a ground terminal, the plurality of electrode units being divided into a plurality of row groups and a plurality of column groups in the circuit, the flexible circuit board having multiple ground lines and multiple dual-purpose signal lines, the ground terminals of the temperature sensors located in the same row group being short-circuited through the same ground line, and the ground terminals of the temperature sensors located in different rows being short-circuited through the same ground line.The grounding terminals of the temperature sensors in the same row are connected in parallel through different grounding lines. The signal terminals of the temperature sensors in the same column are short-circuited through the same dual-purpose signal line. The signal terminals of the temperature sensors in different columns are connected in parallel through different dual-purpose signal lines. The electrode has a first mode for applying an AC signal and a second mode for acquiring temperature. Each dual-purpose signal line transmits an AC signal to each dielectric element in the first mode and transmits a DC signal to the signal terminal of each temperature sensor and the temperature signal detected by each temperature sensor in the second mode. Each grounding line is disconnected in the first mode and sequentially turned on individually in the second mode. An electric field generator or adapter is electrically connected to the electrode. The adapter or electric field generator provides an AC signal to each dielectric element of the electrode or a DC signal to the signal terminal of each temperature sensor through each dual-purpose signal line. The adapter or electric field generator performs handshake communication with the handshake chip of the electrode. 2. The tumor electric field therapy system according to claim 1, characterized in that the adapter or the electric field generator has a preset temperature threshold, and the adapter or the electric field generator is configured to: control or adjust the AC signal applied to each dielectric element of the electrode sheet according to the comparison result of the temperature signal of each temperature sensor of the electrode sheet with the preset temperature threshold. 3. The tumor electric field therapy system according to claim 2, characterized in that the adapter or the electric field generator is configured to: when the temperature signal is much lower than the preset temperature threshold, continue to apply the AC signal to each dielectric element of the electrode sheet by increasing the voltage or current amplitude of the AC signal currently applied to each dielectric element of the electrode sheet, or continue to apply the AC signal to each dielectric element of the electrode sheet by keeping the voltage or current amplitude of the AC signal currently applied to each dielectric element of the electrode sheet unchanged. 4. The tumor electric field therapy system according to claim 2, wherein the adapter or the electric field generator is configured to: when the temperature signal approaches a preset temperature threshold, continue to apply an AC signal to each dielectric element of the electrode sheet in a manner that maintains the voltage or current amplitude of the AC signal currently applied to each dielectric element of the electrode sheet unchanged, or continue to apply an AC signal to each dielectric element of the electrode sheet in a manner that reduces the voltage or current amplitude of the AC signal currently applied to each dielectric element of the electrode sheet. 5. The tumor electric field therapy system according to claim 2, wherein the adapter or the electric field generator is configured to: when a temperature signal in any of the acquired temperature signals from the temperature sensors of the electrode sheet exceeds a preset temperature threshold...When a temperature threshold is set, the transmission of AC signals to all dielectric elements of the electrode sheet is stopped, or only the application of AC signals to all dielectric elements in the column group containing dielectric elements exceeding the preset temperature threshold is stopped, while the application of AC signals to dielectric elements in the remaining column groups where the temperature signals do not exceed the preset temperature threshold continues. 6. The tumor electric field therapy system according to claim 1, characterized in that the adapter or the electric field generator is provided with a switching unit, the switching unit including multiple grounding switches for controlling the conduction or disconnection of each grounding wire of the electrode sheet and multiple bidirectional switching switches for controlling the transmission of AC signals or DC signals by each dual-purpose signal line of the electrode sheet. 7. The tumor electric field therapy system according to claim 6, characterized in that the adapter is provided with an AC signal line for transmitting alternating current signals, a DC power supply, and an analog-to-digital converter with multiple detection channels; the bidirectional switching switch has an input terminal and a sampling terminal, the input terminal is electrically connected to the AC signal line, and the sampling terminal is electrically connected to the DC power supply and a corresponding detection channel; in a first mode, all or part of the bidirectional switching switches are turned on at their input terminals, and all the grounding switches are turned off; in a second mode, all the bidirectional switching switches are turned on at their sampling terminals, and each of the grounding switches is turned on individually in sequence. 8. The tumor electric field therapy system according to claim 7, characterized in that the electric field generator or the adapter is configured to control the states of each of the grounding switches and each of the bidirectional switching switches. 9. The tumor electric field therapy system according to claim 7, characterized in that the analog-to-digital converter receives the temperature signals detected by each of the temperature sensors and converts them into multiple digital signals; the adapter determines the type of the electrode plate based on the multiple digital signals. 10. The tumor electric field therapy system according to claim 7, characterized in that the adapter determines whether the electrode sheet has a temperature abnormality based on a plurality of digital signals. Claims 2 / 2 Page 3 CN 120983809 A Tumor Electric Field Therapy System

[0001] This application is a divisional application filed by the applicant on October 25, 2024, with application number CN202411499210.X and invention title "Electrode Sheet, Tumor Electric Field Therapy System and Temperature Detection and Signal Control Method". Technical Field

[0002] This application relates to tumor electric field therapy (TTF) technology, and more particularly to a tumor electric field therapy system. Background Art

[0003] Tumor electric field therapy is a method that uses a low-intensity, medium-to-high frequency alternating electric field to inhibit the mitotic process of certain tumor cells.The method of treating tumors involves the formation of spindle microtubules, the inhibition of intracellular organelle separation during cell division, and the induction of apoptosis during mitosis.

[0004] Compared with traditional cancer treatment methods, TTF has an innovative mechanism of action. Some physiological characteristics of tumor cells, such as their geometry and high-frequency mitosis, make them susceptible to the influence of TTF. TTF disrupts the normal aggregation of tubulin by applying directional forces to polar particles (such as macromolecules and organelles) within the cell. These processes may lead to physical damage to the cell membrane and apoptosis. At the end of cell mitosis, the structural morphology of the cleavage groove leads to uneven distribution of the electric field around it. At the same time, under the influence of TTF, the electric field strength at the cleavage groove is significantly enhanced, and charged substances in the cell move towards the cleavage groove, which interferes with or even destroys the formation of cell structure, ultimately leading to cell division failure and apoptosis.

[0005] In existing tumor electric field therapy systems, an electric field generator is used to transmit the alternating current signal for tumor electric field therapy to the electrode pads, and then the alternating electric field is applied to the tumor site of the patient through the electrode pads to perform tumor electric field therapy. When a tumor electric field is applied to a patient's body, heat accumulates at the application site, causing the temperature to rise accordingly. Therefore, it is necessary to monitor the temperature at the application site. If the temperature is too high, the electric field strength needs to be adjusted promptly to avoid the risk of burns to the patient's skin.

[0006] The tumor electric field therapy system includes at least one pair of electrode pads, each containing multiple electrode units. Even when the same alternating current signal is applied to each electrode unit, the heat generated on each electrode unit will vary depending on its location. That is, the temperature of each electrode unit on the entire electrode pad will not be completely uniform. This could result in some electrode units exceeding the preset temperature while others remain at a normal temperature. To ensure that the tumor electric field therapy has a sufficiently long application time while avoiding low-temperature burns to the patient's skin, individual control is required for any overheated electrode units. However, for existing electrode pads, individual control of the electrode units requires setting a conductive trace for each electrode unit in the substrate of the electrode pad. This increases the number of conductive traces in the electrode pad substrate, making the electrode pad difficult to bend, and the cables electrically connected to the electrode pad are also thickened, increasing the overall weight of the electrode pad and making it difficult to apply the electrode pad.

[0007] Therefore, it is necessary to provide an improved tumor electric field therapy system. Summary of the Invention

[0008] The purpose of this application is to provide a tumor electric field therapy system with an electrode pad having dual-purpose signal lines.

[0009] To achieve the above objective, this application provides the following technical solution: a tumor electric field therapy system, comprising: an electrode pad, wherein the electrode pad is provided with a flexible circuit board, a plurality of electrode units disposed on the flexible circuit board, and a handshake chip, wherein the electrode pad is provided with a flexible circuit board, a plurality of electrode units disposed on the flexible circuit board, and a handshake chip, wherein the electrode pad is provided with a flexible circuit board, a plurality of electrode units disposed on the flexible circuit board, and a handshake chip, wherein the electrode pad is provided with a flexible circuit board, a plurality of electrode units disposed on the flexible circuit board, and a handshake chip, wherein the electrode pad is provided with a flexible circuit board, a flexible circuit board substrate ...Each electrode unit includes a dielectric element and a temperature sensor with a signal terminal and a ground terminal. Multiple electrode units are divided into multiple row groups and multiple column groups in the circuit. The flexible circuit board has multiple ground lines and multiple dual-purpose signal lines. The ground terminals of temperature sensors located in the same row group are short-circuited through the same ground line, while the ground terminals of temperature sensors located in different row groups are connected in parallel through different ground lines. The signal terminals of temperature sensors located in the same column group are short-circuited through the same dual-purpose signal line, while the signal terminals of temperature sensors located in different column groups are connected in parallel through different dual-purpose signal lines. The electrode sheet has a first mode for applying an AC signal and a sampling mode. The second mode of temperature collection, each of the dual-purpose signal lines transmits AC signals to each of the dielectric elements in the first mode and transmits DC signals to the signal terminals of each temperature sensor and transmits the temperature signals detected by each of the temperature sensors in the second mode, each of the grounding lines is in an open state in the first mode and is sequentially and individually turned on in the second mode; and an electric field generator or adapter electrically connected to the electrode sheet, the adapter or the electric field generator providing AC signals to each of the dielectric elements of the electrode sheet or providing DC signals to the signal terminals of each of the temperature sensors through each of the dual-purpose signal lines, the adapter or the electric field generator performing handshake communication with the handshake chip of the electrode sheet.

[0010] Further, the adapter or the electric field generator has a preset temperature threshold, the adapter or the electric field generator is configured to: control or adjust the AC signals applied to each of the dielectric elements of the electrode sheet according to the comparison result of the temperature signals of each of the temperature sensors of the electrode sheet and the preset temperature threshold.

[0011] Further, the adapter or the electric field generator is configured to: when the temperature signal is much lower than a preset temperature threshold, continue to apply an AC signal to each dielectric element of the electrode sheet by increasing the voltage or current amplitude of the AC signal currently applied to each dielectric element of the electrode sheet, or continue to apply an AC signal to each dielectric element of the electrode sheet by keeping the voltage or current amplitude of the AC signal currently applied to each dielectric element of the electrode sheet unchanged.

[0012] Further, the adapter or the electric field generator is configured to: when the temperature signal is close to a preset temperature threshold, continue to apply an AC signal to each dielectric element of the electrode sheet by keeping the voltage or current amplitude of the AC signal currently applied to each dielectric element of the electrode sheet unchanged, or continue to apply an AC signal to each dielectric element of the electrode sheet by decreasing the voltage or current amplitude of the AC signal currently applied to each dielectric element of the electrode sheet.

[0013] Furthermore, the adapter or the electric field generator is configured to: when any temperature signal in the temperature signals of the temperature sensors of the electrode sheet exceeds a preset temperature threshold, stop transmitting AC signals to all dielectric elements of the electrode sheet, or only stop applying AC signals to all dielectric elements in the column group where the dielectric elements exceeding the preset temperature threshold are located, and continue applying AC signals to the dielectric elements in the remaining column groups where the temperature signals do not exceed the preset temperature threshold.

[0014] Furthermore, the adapter or the electric field generator is provided with a switching unit, the switching unit including multiple grounding switches that control the conduction or disconnection of each grounding wire of the electrode sheet, and multiple bidirectional switching switches that control the transmission of AC signals or DC signals by each dual-purpose signal line of the electrode sheet.

[0015] Further, the adapter is provided with an AC signal line for transmitting AC signals, a DC power supply, and an analog-to-digital converter with multiple detection channels. The bidirectional switching switch has an input terminal and a sampling terminal. The input terminal is electrically connected to the AC signal line, and the sampling terminal is electrically connected to the DC power supply and a corresponding detection channel. In the first mode, all or part of the bidirectional switching switches are turned on at their input terminals, and all the grounding switches are turned off. In the second mode, all the bidirectional switching switches are turned on at their sampling terminals, and each grounding switch is turned on individually in sequence. Specification 2 / 34 pages 5 CN 120983809 A

[0016] Further, the electric field generator or the adapter combination configures the states of each grounding switch and each bidirectional switching switch.

[0017] Further, the analog-to-digital converter receives the temperature signals detected by each temperature sensor and converts them into multiple digital signals. The adapter determines the type of the electrode plate based on the multiple digital signals.

[0018] Further, the adapter determines whether the electrode sheet has a temperature abnormality based on multiple digital signals.

[0019] The above description is only an overview of the technical solution of this application. In order to better understand the technical means of this application and to implement it according to the contents of the specification, and to make the above and other objects, features and advantages of this application more obvious and understandable, specific embodiments of this application are described below. Brief Description of the Drawings

[0020] FIG1 is a schematic diagram of a tumor electric field therapy system according to an embodiment of this application, which shows a spatial structure schematic diagram of the electrode sheet of the first embodiment;

[0021] FIG2 is a schematic diagram of the structural layout of a modified embodiment of the electrode sheet used in the tumor electric field therapy system shown in FIG1 of this application;

[0022] FIG3 is a circuit connection schematic diagram of the tumor electric field system shown in FIG1 of this application, which shows the circuit connection of the system shown in FIG1.A schematic diagram of the circuit connection between the electrode sheet of the first embodiment or the electrode sheet of the variant embodiment shown in FIG. 2 and the adapter of the first embodiment shown in FIG. 1;

[0023] FIG. 4 is a schematic block diagram of the internal structure of the adapter shown in FIG. 3 of this application;

[0024] FIG. 5 is a schematic block diagram of the internal structure of the electric field generator of the tumor electric field therapy system shown in FIG. 1 of this application;

[0025] FIG. 6 is similar to FIG. 3, and is a schematic diagram of the circuit connection of the tumor electric field therapy system of the second embodiment of this application, showing the circuit connection between the electrode sheet of the second embodiment of the tumor electric field therapy system of this application and the adapter shown in FIG. 3;

[0026] FIG. 7 is similar to FIG. 3, and is a schematic diagram of the circuit connection of the tumor electric field therapy system of the third embodiment of this application, showing the circuit connection between the electrode sheet of the third embodiment of the tumor electric field therapy system of this application and the adapter shown in FIG. 3;

[0027] FIG. 8 is similar to FIG. 3, and is a schematic diagram of the circuit connection of the tumor electric field therapy system of the fourth embodiment of this application, showing the circuit connection between the electrode sheet of the fourth embodiment of the tumor electric field therapy system of this application and the adapter shown in FIG. 3;

[0028] Figure 9 is similar to Figure 3, and is a circuit connection diagram of the tumor electric field therapy system of the fifth embodiment of this application, showing the circuit connection diagram of the electrode sheet used in the fifth embodiment of the tumor electric field therapy system of this application and the adapter shown in Figure 3;

[0029] Figure 10 is a flowchart of a temperature detection method of the tumor electric field therapy system of this application;

[0030] Figure 11 is a flowchart of the tumor electric field therapy system of this application;

[0031] Figure 12 is another flowchart of a temperature detection method of the tumor electric field therapy system of this application;

[0032] Figure 13 is a flowchart of an AC signal application control method for tumor electric field therapy of this application;

[0033] Figure 14 is a flowchart of a signal control method for tumor electric field therapy of this application;

[0034] Figure 15 is a flowchart of an electrode sheet temperature detection method of this application; Specification 3 / 34 pages 6 CN 120983809 A

[0035] Figure 16 is a flowchart of an AC signal application method for tumor electric field therapy of this application.

[0036] Explanation of reference numerals:

[0037] Tumor electric field therapy system 100, electrode sheets 10, 10', 10D, 10E, 10F, 10H, flexible circuit board 11, 11D, 11E, 11F, 11H, connecting part 111, 111', wiring part 112, 112', bridging part 113, 113', main trunk 114, 114', branch 115, 115', first interval D1, D1', second interval D2, D2', electrode unit 12, 12', first cable 13, 13', temperature sensor14. Device, 14-1 (Ground terminal), 14-2 (Signal terminal), 15. Dielectric element, 16. Diode, 17. Handshake chip, 17. Ground trace, 171. Communication line, 172. Ground wire, 18. First ground wire, 18-1, 18-2, 18-3, 18-4, 19. Dual-purpose signal line, 19-1, 19-2, 19-3, 19-4, 19-5, 20. Adapter, 21. Second cable, 22. First controller, 23. Analog-to-digital converter, 24. Voltage divider resistor, 25. Grounding switch, 26. First grounding switch, 27- 1. Second grounding switch 25-2, Third grounding switch 25-3, Fourth grounding switch 25-4, Bidirectional switching switch 26, First bidirectional switching switch 26-1, Second bidirectional switching switch 26-2, Third bidirectional switching switch 26-3, Fourth bidirectional switching switch 26-4, Fifth bidirectional switching switch 26-5, First communication unit 27, AC signal line 28, First power module 29, Communication transmission line 211, Electric field generator 30, Second power module 31, Second controller 32, Second communication unit 33, AC signal generator 34, AC signal switch 35, First AC signal switch 35-1, First AC signal switch 35-2, First AC signal switch 35-3, First AC signal switch 35-4, First connector 40, 40D, 40E, 40F, 40H, First plug 41, 41', First socket 42, Second connector 50, Second plug 51, Second socket 52. Detailed Description of Embodiments

[0038] The embodiments of the technical solutions of this application will be described in detail below with reference to the accompanying drawings. The following embodiments are only used to more clearly illustrate the technical solutions of this application, and are therefore only examples, and cannot be used to limit the scope of protection of this application.

[0039] FIG1 is a schematic diagram of a tumor electric field therapy system 100 according to an embodiment of this application. As shown in FIG1, the tumor electric field therapy system 100 includes: at least one pair of electrode plates 10, an adapter 20 connected to the electrode plates 10, and an electric field generator 30 connected to the adapter 20. The electric field generator 30 generates an alternating current signal for tumor treatment and applies the alternating current signal to the electrode plates 10 through the adapter 20, so that a therapeutic electric field is generated between the paired electrode plates 10. The adapter 20 is electrically connected between the electrode plates 10 and the electric field generator 30, and is used to transmit the alternating current signal generated by the electric field generator 30 to the electrode plates 10. In other words, the electric field generator 30 can generate an alternating current signal, which is transmitted to each electrode pad 10 through the adapter 20, thereby generating a therapeutic electric field for treating tumors between the same pair of electrode pads 10. As shown in Figure 1, in this embodiment, the number of electrode pads 10 is four. From the spatial arrangement, each electrode pad 10 includes components that are both axially symmetrically arranged and...The electrode pad 10 comprises a plurality of electrode units 12 arranged in a centrally symmetrical manner and of equal number, several connecting portions 111 located between adjacent electrode units 12, a bridging portion 113 spanning between adjacent connecting portions 111, a wiring portion 112 connected to the bridging portion 113, and a first cable 13 connected to the wiring portion 112. The bridging portion 113 and the wiring portion 112 are arranged perpendicularly to each other, forming a "T" shape. The bridging portion 113 is spanned between adjacent connecting portions 111. Each electrode unit 12 of the electrode pad 10 is electrically connected to the adapter 20 via a first cable 13 having 10 core wires.

[0040] Each electrode unit 12 has a temperature sensor 14 and a dielectric element 15. The temperature sensor 14 is used to detect the temperature of the part of the electrode unit 12 applied to the patient's body surface. It can be a thermistor element or a temperature sensor other than a thermistor, and can be set at any position on the electrode unit 12. The dielectric element 15 is used to apply an alternating current signal to the tumor site of the patient. The dielectric element 15 can be a dielectric ceramic sheet or a polymer dielectric layer made of polymer material. In this embodiment, each dielectric element 15 has a through hole (not labeled) in the middle for receiving a corresponding temperature sensor 14. Each electrode unit 12 may also include a diode 16 connected in series with the temperature sensor 14 to prevent reverse current flow and prevent detection signals from other electrode units 12 from affecting the temperature sensor 14. The ground terminal 14-1 of the temperature sensor 14 is connected in series with the anode of the diode 16 and grounded through the cathode of the diode 16.

[0041] In the first mode, the electrode unit 12 applies an alternating current signal through the dielectric element 15; in the second mode, the temperature of the patient's body surface to which the corresponding electrode unit 12 is applied is detected or collected by the temperature sensor 14; in the third mode, the application of the alternating current signal is stopped and temperature detection and collection are stopped. The first mode, the second mode, and the third mode do not overlap in time. That is, the time period during which the dielectric element 15 of the electrode unit 12 applies an AC signal is staggered and does not overlap with the time period during which the temperature sensor 14 detects the temperature. The electrode unit 12 can cycle between applying an AC signal through its dielectric element 15 and detecting the temperature through its temperature sensor 14, that is, the electrode unit 12 can cycle between the first mode and the second mode. The electrode unit 12 can also cycle between the first mode, the second mode, and the third mode, that is, the electrode unit 12 cycles between applying an AC signal through the dielectric element 15, collecting or detecting the temperature through the temperature sensor 14, stopping the application of the AC signal, and collecting the temperature.

[0042] Each electrode sheet 10 includes an electrode array (not labeled) composed of 20 electrode units 12. Electrode array (not labeled)The circuit board 11 (notation) also includes a connecting portion 111, a wiring portion 112, and a bridging portion 113. Twenty electrode units 12 are spaced apart in an electrode array (notation) arranged in four rows and six columns. Specifically, the first and last rows each have four electrode units 12, and the middle two rows each have six electrode units 12. The four electrode units 12 in the first row are located in the second to fifth columns, the six electrode units 12 in each of the middle two rows are located in the first to sixth columns, and the four electrode units 12 in the last row are also located in the second to fifth columns. The connecting portion 111 is only located between adjacent electrode units 12 arranged in the column direction in the third and fourth columns, and between adjacent electrode units 12 in the row direction in each row, except for the two electrode units 12 located in the third and fourth columns of each row. That is, the two adjacent electrode units 12 in the third and fourth columns are connected only in the column direction by the connecting part 111, and are disconnected in the row direction without being connected by the connecting part 111; the electrode units 12 in the first, second, fifth and sixth columns are connected only by the horizontally arranged connecting part 111 and the electrode unit 12 adjacent to them in the row direction, and are disconnected in the column direction and with the adjacent electrode units 12. In other words, the two adjacent electrode units 12 in the column direction in the first, second, fifth and sixth columns are disconnected.

[0043] The electrode unit 12 in the third column and the connecting part 111 between the electrode units 12 in that column and arranged vertically, and the electrode unit 12 in the fourth column and the connecting part 111 between the electrode units 12 in that column and also arranged vertically, all constitute the backbone 114 of the electrode array (unlabeled). The connecting portions 111 located on opposite sides of the electrode units 12 in the third and fourth columns, and connected to each electrode unit 12 in the third and fourth columns respectively via laterally arranged connecting portions 111, constitute branches 115 of the electrode array (unlabeled). That is, in this embodiment, the electrode array (unlabeled) includes two main trunks 114 and several branches 115 extending laterally from each of the two main trunks 114. Each branch 115 has a free end away from the main trunk 114, and the free ends of adjacent branches 115 are disconnected. The position and distance between adjacent branches 115 can be freely adjusted according to actual usage requirements. Specifically, one main trunk 114 is composed of each electrode unit 12 in the third column and a connecting portion 111 located between adjacent electrode units 12 in that column and arranged longitudinally; the other main trunk 114 is composed of each electrode unit 12 in the fourth column and a connecting portion 111 located between adjacent electrode units 12 in that column and arranged longitudinally. The rest are connected to the main trunk via horizontally arranged connecting parts 111.Each electrode unit 12 on 114 and the horizontally arranged connecting portion 111 are branches 115.

[0044] Specifically, the branches 115 are as follows: a connecting portion 111 extending laterally to the left from the electrode unit 12 in the first row of the third column and located in the first row, and an electrode unit 12 connected to the connecting portion 111 and located in the second column of the first row; two connecting portions 111 extending laterally to the left from the electrode unit 12 in the second row of the third column and located in the second row, and two electrode units 12 located in the first column and the second column of the second row; two connecting portions 111 extending laterally to the left from the electrode unit 12 in the third column and located in the third row, and two electrode units 12 located in the first column and the second column of the third row; a connecting portion 111 extending laterally to the left from the electrode unit 12 in the third column and located in the fourth row, and an electrode unit 12 located in the second column of the fourth row; from the fourth column... A connecting portion 111 is provided on the first row of electrode units 12 extending laterally to the right and located in the fifth column of the first row; two connecting portions 111 are provided on the second row of electrode units 12 extending laterally to the right and located in the second row, and two electrode units 12 are located in the fifth and sixth columns of the second row; two connecting portions 111 are provided on the third row of electrode units 12 extending laterally to the right and located in the third row, and two electrode units 12 are located in the fifth and sixth columns of the third row; a connecting portion 111 is provided on the fourth row of electrode units 12 extending laterally to the right and located in the fourth row, and an electrode unit 12 is located in the fifth column of the fourth row.

[0045] The electrode array (unlabeled) is divided into a symmetrical left portion including three columns on the left and a right portion including three columns on the right, and the left and right portions are connected only by a bridging portion 113. The left side is composed of a main stem 114 located in the third column and several branches 115 extending laterally to the left from the main stem 114. The right side is composed of a main stem 114 located in the fourth column and several branches 115 extending laterally to the right from the main stem 115. The two main stems 114 are connected by a bridging portion 113. Specifically, the two main stems 114 are electrically connected by a bridging portion 113 between the connecting portions 111 of the electrode units 12 in the second row of the third column and the connecting portions 111 of the electrode units 12 in the second row of the fourth column and the connecting portions 111 of the electrode units 12 in the third row of the fourth column. The connecting portions 111 of the electrode units 12 in the second row of the third column and the connecting portions 111 of the electrode units 12 in the second row of the fourth column and the connecting portions 113 are generally arranged in an "H" shape. In other embodiments, the bridging portion 113 may also be...An electrode unit 112 located in the third column and an electrode unit 12 located in the fourth column are provided. Optionally, a bridging portion 113 is provided between two electrode units 12 located in the third and fourth columns and adjacent in the row direction.

[0046] Each electrode unit 12 can be divided into peripheral electrode units 12 and central electrode units 12 according to its position in the electrode array (unlabeled). The peripheral electrode units 12 include four electrode units 12 located in the first row, two electrode units 12 located at opposite ends of the second row, two electrode units 12 located at opposite ends of the third row, and four electrode units 12 located in the fourth row. The central electrode units 12 include four electrode units 12 located in the middle of the second row and four electrode units 12 located in the middle of the third row. Among the multiple peripheral electrode units 12, some adjacent electrode units 12 are connected by a horizontally arranged connecting portion 111, and some adjacent electrode units 12 are disconnected. Among the multiple electrode units 12 located on the periphery, adjacent electrode units 12 connected by connecting portions 111 are partially row-adjacent electrode units 12. Specifically, among the multiple electrode units 12 located on the periphery, electrode units 12 that are adjacent in column direction or diagonally adjacent are all disconnected; electrode units 12 that are partially row-adjacent are also disconnected; only electrode units 12 that are partially row-adjacent are connected by laterally extending connecting portions 111. Among the multiple electrode units 12 located in the center, only electrode units 12 that are adjacent in column direction on the main branch 114 are connected by longitudinally arranged connecting portions 111, and only electrode units 12 that are adjacent in row direction on the branch 115 are connected by laterally arranged connecting portions 111.

[0047] The electrode array (unlabeled) also has gaps (unlabeled) formed between a plurality of spaced electrode units 12, which allow moisture from the patient's skin to escape, heat exchange between the patient's skin and the outside world, or free breathing of the patient's skin. It also allows for free adjustment of the position and spacing between the branches 115, and avoids wrinkling when the electrode pads 10 are applied. The gaps (unlabeled) include a first gap D1 located between the two main branches 114 and a second gap D2 located between the branches 115. The first gap D1 is located between the third and fourth columns of electrode units 12, and the second gap D2 is located between adjacent rows of units 12. That is, moving upwards along the row, the electrode unit 12 in the third column is disconnected from the adjacent electrode unit 12 in the fourth column, without a connecting part 111, forming the aforementioned first interval D1; and moving upwards along the column, only the two adjacent electrode units 12 in the third and fourth columns are connected by the connecting part 111, while the two adjacent electrode units 12 in the other four columns are not connected by the connecting part 111, forming the aforementioned second interval D2. The arrangement of the first and second intervals D1 and D2 is also possible.To increase the degree of freedom of some electrode units 12, wrinkles can also be avoided when attaching the electrode sheet 10.

[0048] The electrode sheet 10 also includes a handshake chip 17 disposed on the flexible circuit board 11 and used to confirm its connection status. The handshake chip 17 can communicate with the electric field generator 30 through the adapter 20 to determine the connection status between the electrode sheet 10 and the adapter 20. The electric field generator 30 of the tumor electric field therapy system 100 first sends a handshake communication signal to the handshake chip 17 of the electrode sheet 10 through the adapter 20, and determines the connection status of the electrode sheet 10 based on whether it receives feedback from the handshake chip 17. After confirming that the electrode sheet 10 is connected normally through the handshake chip 17, the electric field generator 30 of the tumor electric field therapy system 100 applies an AC signal to the dielectric element 15 of the electrode sheet 10 or transmits a DC signal to each temperature sensor 14 of the electrode sheet 10 to collect temperature detection signals. The handshake chip 17 can be an EEPROM with encryption function.

[0049] In some other embodiments, the tumor electric field therapy system 100 may have more or fewer electrode pads 10. In some other embodiments, each pair of electrode pads 10 may have the same or different numbers of electrode units 12, and different pairs of electrode pads 10 may also have different numbers of electrode units 12. In some other embodiments, the 20 electrode units 12 may also be arranged in other ways. Of course, in some other embodiments, the electrode pads 10 may also have other numbers of electrode units 12. In some other embodiments, the 20 electrode units 12 may also be arranged in other ways, as shown in electrode pad 10' in FIG2. Of course, in some other embodiments, the electrode pads 10 may also have other numbers of electrode units 12. In summary, the implementation of this application is not limited by the number and arrangement of the electrode units 12 of the electrode pads 10.

[0050] The electrode sheet 10' shown in FIG2 is a modified embodiment of the electrode sheet 10 shown in FIG1. ​​The spatial structure of the electrode sheet 10' is the same as that of the electrode sheet 10, and it also includes a plurality of electrode units 12' arranged at intervals, a plurality of connecting portions 111' located between two adjacent electrode units 12', a wiring portion 112' connected to the bridging portion 113', a first cable 13' connected to the wiring portion 112', a first interval D1 formed between the third column electrode units 12' and the fourth column electrode units 12', and a second interval D2' formed between the electrode units 12' in adjacent rows; the connecting portion 111', the wiring portion 112', and the bridging portion 113' also constitute a flexible circuit board (not labeled), and the electrode sheet 10' is also plugged into the adapter 20 through the first plug 41' of the first cable 13' with 10 core wires. The only difference is that the two adjacent electrode units 12' in the fourth column are arranged in a disconnected state. They are not connected by the longitudinally arranged connecting part 111', but are connected between two adjacent electrode units 12' in the fifth column.The vertically arranged connecting parts 111' connect each electrode unit 12' in the fourth column to the electrode unit 12' in the fifth column that is adjacent in the row direction, respectively, through the horizontally arranged connecting parts 111'; and the bridging part 113' connects the two electrode units 12' located in the third row and third column and the two electrode units 12' located in the third row and fourth column. One main branch 114' is composed of the electrode unit 12' located in the third column and the connecting parts 111' located between the electrode units 12' in that column, and the other main branch 114' is composed of the electrode unit 12' located in the fifth column and the connecting parts 111' located between the electrode units 12' in that column. The structure of the left side of the left three columns of the electrode array (unlabeled) is exactly the same as the structure of the left side of the electrode array (unlabeled) shown in Figure 1, except that the right side is branched by branches 115' located on the right side, which are respectively extended to the left and right sides of the corresponding electrode unit 12' in the main branch 114' due to the change in the position of the main branch 114' from the fourth column to the fifth column.

[0051] FIG3 is a schematic diagram of the circuit connection between the electrode sheet 10 of the first embodiment of the tumor electric field therapy system 100 shown in FIG1 or the electrode sheet 10' of the variant embodiment shown in FIG2 and the adapter 20 of the first embodiment. It is worth noting that the arrangement of the electrode units 12 shown in FIG3 is to more clearly show the electrical connection between an electrode sheet 10 and the adapter 20. The arrangement of the electrode units 12 shown in FIG3 does not represent the spatial arrangement of the electrode units 12. The circuit connection is described below using the electrode sheet 10 in the example of CN 120983809 A on page 7 / 34 of the first embodiment specification as an example.

[0052] In conjunction with FIG1 and FIG3, in this embodiment, each electrode sheet 10 is provided with 20 electrode units 12. The 20 electrode units 12 are arranged in the order of 1 to 20 in the circuit connection and are divided into four row groups and five column groups, that is, the 20 electrode units 12 are arranged in four rows and five columns in the circuit connection. Each electrode unit 12 has a temperature sensor 14, including a ground terminal 14-1 and a signal terminal 14-2. The dielectric element 15 and temperature sensor 14 of each electrode unit 12 are soldered onto the flexible circuit board 11, with the dielectric element 15 short-circuited to the signal terminal 14-2 of the corresponding temperature sensor 14. Since the electrode units 12 are arranged in a four-row, five-column configuration in the circuit connection, and each electrode unit includes a corresponding dielectric element 15 and a corresponding temperature sensor 14, the multiple temperature sensors 14 are also arranged in a four-row, five-column configuration in the circuit connection, and the multiple dielectric elements 15 are also arranged in a four-row, five-column configuration in the circuit connection. It should be noted that this arrangement is for clearer illustration of the electrical connection between the electrode sheet 10 and the adapter 20, and does not represent the spatial arrangement of the electrode units 12. The spatial structure may be a roughly array-like structure as shown in Figure 1, or other structures, such as petal-shaped or scattering structures.The structure can be regular or irregular. The dielectric element 15 is configured to apply an alternating electric field to the tumor site of the patient. The temperature sensor 14 is configured to detect the temperature of the patient's body surface that is in contact with the electrode pad 10 and output a temperature detection signal to the adapter 20.

[0053] The flexible circuit board 11 is embedded with multiple conductive traces 171, 172, 18, and 19, which include multiple ground lines 18, multiple dual-purpose signal lines 19, one ground trace 171, and one communication line 172. One end of the ground trace 171 is connected to the ground pin of the handshake chip 17, and the other end is connected to any one of the ground lines 18. The ground pin of the handshake chip 17 is connected to the ground trace 171, and its communication pin is electrically connected to the communication line 172. That is, the handshake chip 17 is grounded through the ground line 18 connected to the ground trace 171 and communicates with external devices through the communication line 172. Specifically, the handshake chip 17 is grounded via a ground trace 171 connected to its ground pin and a ground line 18. It then sequentially connects to the communication line 172 of the flexible circuit board 11, a wire electrically connected to the first cable 13 and the communication line 172, an adapter 20 electrically connected to the first cable 13, and an electric field generator 30 electrically connected to the adapter 20, thereby determining the connection status of the electrode plate 10. The first cable 13 has multi-core wires (not shown) electrically connected to the communication line 172, the multiple ground lines 18, and the multiple dual-purpose signal lines 19 of the flexible circuit board 11, respectively. The total number of communication lines 172, ground lines 18, and dual-purpose signal lines 19 embedded in the flexible circuit board 11 does not exceed 10. Therefore, the number of wires in the first cable 13 does not exceed 11.

[0054] The number of conductive lines electrically connected to the grounding wire 18 in the tumor electric field therapy system 100 is related to the number of rows M of the electrode unit 12, which can be greater than or equal to the number of rows M of the electrode unit 12, where M is a positive integer. The number of conductive lines electrically connected to the dual-purpose signal line 19 in the tumor electric field therapy system 100 is related to the number of columns N of the electrode unit 12, which can be greater than or equal to the number of columns N of the electrode unit 12, where N is a positive integer. In this embodiment, the number of grounding wires 18 is equal to the number of rows M of the electrode unit 12; the number of columns N of the dual-purpose signal line 19 is equal to the number of columns N of the electrode unit 12. The number of lines L embedded in the flexible circuit board 11 is equal to the sum of the number of grounding wires 18 and the number of dual-purpose signal lines 19 plus 2, that is, L = M + N + 2. The number of conductors in the first cable 13 is M + N + 1.

[0055] The multi-purpose signal lines 19 of the flexible circuit board 11 are respectively arranged in a one-to-one correspondence with multiple columns of the electrode units 12, and are configured to transmit the AC signal generated by the electric field generator 30 to each electrode unit 12 in the corresponding column.Dielectric element 15. That is, dielectric elements 15 located in the same column group are all short-circuited through the same dual-purpose signal line 19 of the flexible circuit board 11, and dielectric elements 15 located in different column groups are connected in parallel through different dual-purpose signal lines 19 of the flexible circuit board 11. The dual-purpose signal lines 19 of the flexible circuit board 11 are electrically connected to the corresponding wires in the first cable 13, and then electrically connected to the electric field generator 30 through the adapter 20. That is, the dual-purpose signal lines 19 of the flexible circuit board 11 receive the AC signal generated by the electric field generator 30 through the first cable 13 and the adapter 20. Specification 8 / 34 page 11 CN 120983809 A

[0056] The multiple grounding lines 18 are respectively set to correspond one-to-one with the multiple rows of the electrode unit 12, and the multiple grounding lines 18 are respectively used to short-circuit and ground the temperature sensor 14 of each corresponding electrode unit 12 in each row group. That is, the grounding terminals 14-1 of multiple temperature sensors 14 located in the same row group are all short-circuited through the same grounding line 18 of the flexible circuit board 11, and the grounding terminals 14-1 of temperature sensors 14 located in different row groups are connected in parallel through different grounding lines 18 of the flexible circuit board 11. During the temperature detection period or in the second mode, only one of the multiple grounding lines 18 is conducting at any given time, and the rest are disconnected.

[0057] Each of the multiple dual-purpose signal lines 19 is also configured to transmit DC signals to the temperature sensor 14 in each electrode unit 12 in the corresponding column group to collect and transmit the detected temperature detection signal. The signal terminals 14-2 of multiple temperature sensors 14 located in different column groups are connected in parallel through different dual-purpose signal lines 19 of the flexible circuit board 11, and the signal terminals 14-2 of multiple temperature sensors 14 located in the same column group are all short-circuited to the same dual-purpose signal line 19 of the flexible circuit board 11, and the short-circuit point serves as a temperature sampling point. Specifically, each dual-purpose signal line 19 is configured to short-connect the signal terminal 14-2 of the temperature sensor 14 of at most one electrode unit 12 in each row group to an external device for receiving detection signals. The signal terminals 14-2 of the temperature sensors 14 connected to each of the multiple dual-purpose signal lines 19 are different to avoid duplicate signals output by the dual-purpose signal lines 19. That is, when the number of electrode units 12 in a row group is the same as the number of dual-purpose signal lines 19, each dual-purpose signal line 19 is electrically connected to the signal terminal 14-2 of the temperature sensor 14 of a different electrode unit 12 in that row group; when the number of electrode units 12 in a row group is less than the number of dual-purpose signal lines 19, at least one dual-purpose signal line 19 is not electrically connected to the signal terminal 14-2 of the temperature sensor 14 of the electrode unit 12, and the remaining dual-purpose signal lines 19 are electrically connected to the signal terminals 14-2 of the temperature sensors 14 of a different electrode unit 12 in that row group.The signal terminal 14-2 of the temperature sensor 14. In this embodiment, the external device for receiving the detection signal is the adapter 20. The dual-purpose signal line 19 of the flexible circuit board 11 receives the DC signal from the adapter 20 or the electric field generator 30 through the first cable 13, and transmits the collected or detected temperature signal to the adapter 20, and then to the electric field generator 30 through the adapter 20.

[0058] In this embodiment, when each electrode unit 12 is equipped with a temperature sensor 14 for temperature detection, the above-mentioned circuit design reduces the number of wires in the first cable 13, avoiding the cable from becoming thicker and harder, thus increasing the difficulty of cable fixation; at the same time, it avoids the increased number of wires in the first cable 13 affecting the adhesion effect between the electrode sheet 10 and the corresponding body surface of the patient's tumor site.

[0059] The grounding wire 18 and the dual-purpose signal line 19 embedded in the flexible circuit board 11 have a total of 9 lines. In this embodiment, the grounding wire 18 embedded in the flexible circuit board 11 has 4 lines, and the dual-purpose signal line 19 has 5 lines. Specifically, the electrode sheet 10 in this embodiment includes four grounding wires 18, each grounding wire 18 being used to ground the grounding terminals 14-1 of the temperature sensors 14 in the same row group. The four grounding wires 18 of the electrode sheet 10 are respectively the first grounding wire 18-1, the second grounding wire 18-2, the third grounding wire 18-3, and the fourth grounding wire 18-4. In the four rows of the electrode sheet 10, the first row group includes electrode units 12-1 to 12-5, the second row group includes electrode units 12-6 to 12-10, the third row group includes electrode units 12-11 to 12-15, and the fourth row group includes electrode units 12-16 to 12-20. Specifically, the first grounding wire 18-1 is used to ground electrode units 12-1 to 12-5 in the first row group; the second grounding wire 18-2 is used to ground electrode units 12-6 to 12-10 in the second row group; the third grounding wire 18-3 is used to ground electrode units 12-11 to 12-15 in the third row group; and the fourth grounding wire 18-4 is used to ground electrode units 12-16 to 12-20 in the fourth row group. It should be noted that these grounding wires 18 can be selectively closed or opened, which can be achieved by connecting each grounding wire 18 in series with a switch, as will be described in detail below. The phrase "grounding electrode unit 12" can refer to grounding the grounding terminal 14-1 of the temperature sensor 14 in electrode unit 12, or it can refer to the diode 16 being connected in series with the temperature sensor 14 in the same electrode unit 12 and grounded together. In short, each grounding wire 18 shorts and grounds the grounding terminal 14-1 of the temperature sensor 14 of the corresponding electrode unit 12 in the instruction manual (page 9 / 34, CN 120983809 A). The fourth grounding wire 18-4 is also connected to the handshake core.The grounding trace 171 connected to the grounding pin of the plate 17 is shorted.

[0060] Continuing to refer to FIG3, the electrode plate 10 of this embodiment also includes five dual-purpose signal lines 19. One end of each dual-purpose signal line 19 is connected to all electrode units 12 in each column group, and the other end is connected to an adapter 20 for receiving temperature detection signals and transmitting AC signals. That is, for each row group, each dual-purpose signal line 19 can be selectively connected to one of the electrode units 12 or not connected to any of the electrode units 12 in that row group to avoid the dual-purpose signal line 19 outputting repeated signals in the future. Specifically, the five dual-purpose signal lines 19 of the electrode plate 10 include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the four electrode units 12 (electrode units 12-1, 12-6, 12-11, and 12-16) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the electrode units 12-2, 12-7, and 12-... 12. Each of the four electrode units 12 (12-17) has its own dielectric element 15 and its own temperature sensor 14 signal terminal 14-2. One end of the third dual-purpose signal line 19-3 is connected to the dielectric element 15 and its own temperature sensor 14 signal terminal 14-2 of each of the four electrode units 12 (12-3, 12-8, 12-13, 12-18). One end of the fourth dual-purpose signal line 19-4 is connected to the dielectric element 15 and its own temperature sensor 14 signal terminal 14-2 of each of the four electrode units 12 (12-4, 12-9, 12-14, 12-19). One end of the fifth dual-purpose signal line 19-5 is connected to the dielectric element 15 and its own temperature sensor 14 signal terminal 14-2 of each of the four electrode units 12 (12-5, 12-10, 12-15, 12-20). In short, each dual-purpose signal line 19 short-circuits the signal terminals 14-2 of each dielectric element 15 and each temperature sensor 14 in the same column group and connects them in parallel for connection to external devices. It should be noted that these dual-purpose signal lines 19 can selectively transmit AC signals or receive temperature detection signals. This can be achieved by connecting each dual-purpose signal line 19 in series with a bidirectional switch 26 and coordinating with the closing or opening of the grounding wire 18, which will be described in detail below.

[0061] In other embodiments, the wiring of the grounding wire 18 and the dual-purpose signal line 19 embedded in the flexible circuit board 11 can also be adjusted according to...The number of electrode units 12 varies depending on the circuit arrangement and quantity of different electrode sheets, which will be specifically described in subsequent embodiments.

[0062] In this embodiment, the grounding pin of the handshake chip 17 used to confirm the connection status of the electrode sheet 10 is connected to the fourth grounding line 18-4 through the grounding trace 171 embedded on the flexible circuit board 11. The first cable 13 has 10 core wires, namely 4 grounding lines 18, 5 dual-purpose signal lines 19 and 1 communication line 172. The specific connection relationship and working principle of the handshake chip 17 will be described in detail below.

[0063] The tumor electric field therapy system 100 of this embodiment includes at least one pair of the above-mentioned electrode sheets 10, an adapter 20 electrically connected to the electrode sheet 10 and an electric field generator 30 electrically connected to the adapter 20. The adapter 20 is connected between the electrode sheet 10 and the electric field generator 30. When the grounding pin of the handshake chip 17 is grounded under the control of the electric field generator 30 or the adapter 20, the electric field generator 30 sends a handshake communication signal to the handshake chip 17 of the electrode 10 via the communication line 172 of the adapter 20 and the electrode 10 to determine the connection status of the electrode 10. When the electrode 10 is connected normally, the electric field generator 30 provides an AC signal to the dielectric element 15 in the multiple electrode units 12 of the electrode 10 via the dual-purpose signal line 19 of the adapter 20 and the electrode 10, or provides a DC signal to the temperature sensor 14 in the multiple electrode units 12 of the electrode 10 via the dual-purpose signal line 19 of the adapter 20 and the electrode 10, and is used to receive the temperature detection signal output by the temperature sensor 14 in the multiple electrode units 12. The adapter 20 is configured to send a handshake communication signal to the communication line 172 of the electrode plate 10 according to the communication command of the electric field generator 30, and is configured to transmit the AC signal generated by the electric field generator 30 to the dual-purpose signal line 19 of the electrode plate 10. It is also configured to transmit DC signals to the dual-purpose signal line 19 of the electrode plate and receive the temperature detection signal output by the multiplex dual-purpose signal line 19 of the electrode plate 10.

[0064] Referring again to Figures 3 and 4, the adapter 20 includes: a first controller 22, a multi-channel communication transmission line 211 electrically connected to the first controller 22, multiple sets of analog-to-digital converters 23 connected to the first controller 22, multiple sets of voltage-reducing resistors 24 and multiple sets of grounding switches 25 corresponding to each set of analog-to-digital converters 23, multiple sets of bidirectional switching switches 26 corresponding to each set of analog-to-digital converters 23, a first communication unit 27, AC signal lines 28 corresponding to each set of bidirectional switching switches 26, and a first power module 29 simultaneously connected to the first communication unit 27, the first controller 22, and the multiple sets of analog-to-digital converters 23.A power module 29 provides DC power VCC to the various electronic components of the adapter 20. The adapter 20 also includes multiple circuit lines (unlabeled). These multiple circuit lines (unlabeled) are electrically connected one-to-one with the multiple ground lines 18, multiple dual-purpose signal lines 19, and communication lines 172 in the flexible circuit board 11 of the corresponding electrode plates 10 via the first cable 13 of the respective electrode plates 10. The multiple circuit lines (unlabeled) include multiple AC signal lines 28 that transmit AC signals to the corresponding electrode 10 and are electrically connected to the multi-purpose signal lines 19 in the flexible circuit board 11 of the corresponding electrode 10; multiple circuit lines (unlabeled) that are electrically connected one-to-one to the multi-purpose signal lines 19 in the flexible circuit board 11 of the corresponding electrode 10 and are used to power the temperature sensors 14 of the electrode 10 or transmit the temperature detection signals of the electrode 10; multiple circuit lines (unlabeled) that are electrically connected one-to-one to the grounding lines 18 in the flexible circuit board 11 of the corresponding electrode 10; and multiple communication transmission lines 211 that are electrically connected one-to-one to the communication lines 172 in the flexible circuit board 11 of the corresponding electrode 10. All communication transmission lines 211 are connected to the first controller 22. Each communication transmission line 211 is connected to the communication line 172 of the flexible circuit board 11 through the corresponding first connector 40, and the first controller 22 and the handshake chip 17 are electrically connected to the handshake chip 17 by shorting the grounding pin of the handshake chip 17 of the closed flexible circuit board 11 through the grounding switch 25 corresponding to the grounding line 18. This enables the handshake chip 17 to obtain power and enable the data communication function.

[0065] The number P of the circuit lines P that the adapter 20 is electrically connected to one electrode piece 10 is equal to the sum of the number of rows M and the number of columns N of the electrode unit 12 of the electrode piece 10 plus 2; the number H of the circuit lines H that the adapter 20 is electrically connected to X electrode pieces 10 is equal to X times the number of circuit lines that it is electrically connected to a single electrode piece 10. The number of grounding switches 25, the number of bidirectional switching switches 26, the number of AC lines 28, and the number of communication transmission lines 211 are all related to the number of electrode pieces 10. The number of grounding switches 25, the number of bidirectional switching switches 26, the number of AC lines 28, and the number of communication transmission lines 211 are all the same; and not less than the number of electrode pieces 10. Preferably, the number of grounding switches 25, the number of bidirectional switching switches 26, the number of AC lines 28, and the number of communication transmission lines 211 are all the same as the number of electrode pieces 10. The following is a detailed description of the electrical connection between an electrode piece 10 with 20 electrode units 12 and the adapter 20.

[0066] Each group of grounding switches 25 is provided with multiple grounding switches 25, and the multiple grounding switches 25 are respectively connected to the adapter 20 and respectively electrically connected to the circuit lines (unlabeled) corresponding one-to-one with the multiple grounding lines 18 of a corresponding electrode piece 10, andConfigured to control the on / off state of multiple grounding wires 18. The circuit lines (unlabeled) of the multiple grounding wires 18, each electrically connected to an electrode piece 10, are grounded at the end near the grounding switch 25. The number of grounding switches 25 in each group is related to the number of grounding wires 18 on the flexible circuit board 11 of the corresponding electrode piece 10; in this embodiment, both are equal. As shown in FIG3, in this embodiment, each group of grounding switches 25 includes a first grounding switch 25-1, a second grounding switch 25-2, a third grounding switch 25-3, and a fourth grounding switch 25-4. Each group of multiple grounding switches 25 controls the closing or opening of a corresponding grounding wire 18 for a given electrode piece 10. Specifically, the first grounding switch 25-1 is used to control the opening or closing of the first grounding wire 18-1 of the corresponding electrode plate 10, and can cooperate with the corresponding set of bidirectional switching switches 26 to control the energization and de-energization of each temperature sensor 14 of the five electrode units 12 from electrode unit 12-1 to electrode unit 12-5 in the first row of the electrode plate 10; the second grounding switch 25-2 is used to control the opening or closing of the second grounding wire 18-2 of the electrode plate 10, and can cooperate with the corresponding set of bidirectional switching switches 26 to control the energization and de-energization of each temperature sensor 14 of the five electrode units 12 from electrode unit 12-6 to electrode unit 12-10 in the second row of the electrode plate 10; the third grounding switch 25-3 is used to control the opening or closing of the third grounding wire 18-3 of the electrode plate 10, and can cooperate with the corresponding set of bidirectional switching switches 26 to control the energization and de-energization of each temperature sensor 14 of the five electrode units 12 from electrode unit 12-6 to electrode unit 12-10 in the third row of the electrode plate 10. The temperature sensors 14 of each of the five electrode units 12 in units 12-15 are energized and de-energized; the fourth grounding switch 25-4 is used to control the closing or opening of the fourth grounding wire 18-4 of the electrode plate 10, and then judges the connection status of the electrode plate 10 by the electrical connection status of the communication line 172 of the handshake chip 17 and the communication transmission line 211 of the adapter 20, and can also cooperate with the corresponding set of bidirectional switching switches 26 to control the energization and de-energization of the temperature sensors 14 of each of the five electrode units 12 in the fourth row group of the electrode plate 10 from electrode unit 12-16 to electrode unit 12-20. The grounding switch 25 can be a mechanical switch, such as a relay. The grounding switch 25 can also be an electronic switch, and each grounding switch 25 can be opened and closed by the first controller 22 of the adapter 20.

[0067] In this embodiment, multiple sets of grounding switches 25 are all electronic switches. The first controller 22 is communicatively connected to multiple sets of grounding switches 25, and is used to sequentially and cyclically control the opening and closing states of multiple grounding switches 25 in each set of grounding switches 25, thereby sequentially and individually activating each of the multiple grounding wires 18 in the corresponding electrode plate 10 and cooperating with the corresponding bidirectional switching switch 26.The switching is performed to sequentially collect the patient's body surface temperature detected by all temperature sensors 14 on the electrode pad 10. The number of grounding switches 25 in each group is greater than or equal to the number of grounding wires 18 on the flexible circuit board 11 of the corresponding electrode pad 10. In this embodiment, the number of grounding switches 25 in each group is the same as the number of grounding wires 18 on the corresponding electrode pad 10.

[0068] Each group of bidirectional switching switches 26 is provided with multiple bidirectional switching switches 26. The multiple bidirectional switching switches 26 in each group are respectively connected to the adapter 20 and electrically connected to the circuit lines (unlabeled) corresponding one-to-one with the multi-channel dual-purpose signal lines 19 of the corresponding electrode pad 10. The number of bidirectional switching switches 26 in each group of bidirectional switching switches 26 is related to the number of dual-purpose signal lines 19 on the flexible circuit board 11 of the corresponding electrode pad 10, which is greater than or equal to the number of dual-purpose signal lines 19 on the flexible circuit board 11 of the corresponding electrode pad 10. In the embodiment shown in FIG3, the two are equal. Each bidirectional switch 26 has a sampling terminal 1 and an input terminal 2. The sampling terminals 1 of multiple bidirectional switches 26 in the same group are electrically connected to the corresponding detection channels of multiple detection channels of a corresponding group of analog-to-digital converters 23, and each detection channel corresponds to a corresponding temperature sampling point. The input terminal 2 of each bidirectional switch 26 in the same group is electrically connected to the corresponding AC signal line 28. Each bidirectional switch 26 is configured to control the multiplexer signal line 19 to connect to the corresponding AC signal line 28 to transmit AC signals or to connect to the corresponding detection channel of the corresponding group of analog-to-digital converters 23 to receive the temperature detection signal output by the temperature sensor 14.

[0069] As shown in FIG3, taking the electrical connection of an electrode plate 10 with the adapter 20 as an example, in this embodiment with 20 electrode units 12, the multiple bidirectional switches 26 are respectively the first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4, and the fifth bidirectional switch 26-5. Multiple bidirectional switching switches 26 in the same group control the switching of a corresponding dual-purpose signal line 19 of the same electrode plate 10 between transmitting AC signals and transmitting temperature detection signals.

[0070] Specifically, the first bidirectional switching switch 26-1 is used to control the switching of the first dual-purpose signal line 19-1 of the corresponding electrode plate 10 between transmitting AC signals and transmitting temperature detection signals, thereby controlling the conduction of each dielectric element 15 of the electrode unit 12-1, electrode unit 12-6, electrode unit 12-11, and electrode unit 12-16 in the first column of the electrode plate 10 and the temperature sensor 14 of each electrode unit 12-1, electrode unit 12-6, electrode unit 12-11, and electrode unit 12-16 in the first column of the electrode plate 10.The switching between the conduction of signal terminal 14-2 and the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4 is coordinated to enable the first column of electrode units 12-1, 12-6, 12-11, and 12-16 to transmit AC signals to the patient or output temperature detection signals collected by the temperature sensor 14 of these electrode units 12 to the corresponding analog-to-digital converter 23; the second bidirectional switching switch 26-2 is used to control the switching between transmitting AC signals and transmitting temperature detection signals of the second dual-purpose signal line 19-2 of the corresponding electrode pad 10, thereby controlling the electrode units 12-2, 12-7, 12-12, and 12-17 in the second column of the electrode pad 10. The switching between the conduction of each dielectric element 15 and the conduction of the signal terminals 14-2 of each temperature sensor 14 of the electrode units 12-2, 12-7, 12-12, and 12-17 in the second column group, and in conjunction with the corresponding grounding switches 25-1, 25-2, 25-3, and 25-4, enables the second column of electrode units 12-2, 12-7, 12-12, and 12-17 to transmit AC signals to the patient or output temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23; the third bidirectional switching switch 26-3 is used to control the switching of the third dual-purpose signal line 19-3 of the corresponding electrode pad 10 between transmitting AC signals and transmitting temperature detection signals. This controls the switching between the conduction of the dielectric elements 15 of electrode units 12-3, 12-8, 12-13, and 12-18 in the third column of the electrode sheet 10 and the conduction of the signal terminals 14-2 of the temperature sensors 14 in the third column of the electrode unit 12-3, 12-8, 12-13, and 12-18, and the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4. -4 cooperates to enable the third column of electrode units 12-3, 12-8, 12-13, and 12-18 to transmit AC signals to the patient or output temperature detection signals collected by the temperature sensors 14 of the electrode units 12 to the corresponding analog-to-digital converter 23; the fourth bidirectional switch 26-4 is used to control the switching of the fourth dual-purpose signal line 19-4 of the corresponding electrode pad 10 between transmitting AC signals and transmitting temperature detection signals, thereby controlling the electrode units 12-4 and 12-18 in the fourth column of the electrode pad 10.The switching between the conduction of each dielectric element 15 of electrode units 12-9, 12-14, and 12-19 and the conduction of the signal terminals 14-2 of each temperature sensor 14 of electrode units 12-4, 12-9, 12-14, and 12-19 in the fourth column group, and the corresponding first grounding switch 25-1, second grounding switch 25-2, and third grounding switch 25-3, is controlled. The fourth grounding switch 25-4 is used to enable the fourth column of electrode units 12-4, 12-9, 12-14, and 12-19 to transmit AC signals to the patient or output temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23; the fifth bidirectional switching switch 26-5 is used to control the switching of the fifth dual-purpose signal line 19-5 of the corresponding electrode pad 10 between transmitting AC signals and transmitting temperature detection signals, thereby controlling the dielectric elements of each electrode unit 12-5, 12-10, 12-15, and 12-20 in the fifth column of the electrode pad 10. The switching between the conduction of component 15 and the conduction of the signal terminals 14-2 of the temperature sensors 14 of each temperature sensor 14 in the fifth column group of electrode units 12-5, 12-10, 12-15, and 12-20, and cooperating with the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4, enables the fifth column of electrode units 12-5, 12-10, 12-15, and 12-20 to transmit AC signals to the patient or output the temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23.

[0071] When all grounding switches 25 are open and the input terminal 2 of each bidirectional switching switch 26 is on and the sampling terminal 1 is off, AC signals can be transmitted to the dielectric elements 15 of each electrode unit 12 of the corresponding electrode plate 10. When the sampling terminal 1 of each bidirectional switching switch 26 is on and the input terminal 2 is off, it can cooperate with each grounding switch 25 in the corresponding group of grounding switches 25 to transmit the temperature detection signals collected by the temperature sensors 14 of each electrode unit 12 on the electrode plate 10 in a time-division manner. The bidirectional switching switch 26 can be a mechanical switch, such as a relay. The bidirectional switching switch 26 can also be an electronic switch, and the switching between the sampling terminal 1 and the input terminal 2 of each bidirectional switching switch 26 can be controlled by the first controller 22 of the adapter 20.

[0072] In this embodiment, all of the multiple bidirectional switching switches 26 are electronic switches. The first controller 22 is communicatively connected to multiple sets of bidirectional switching switches 26, and is used to control the multiple bidirectional switching switches 26 in each set of bidirectional switching switches 26 at their respective sampling terminals. (Instruction manual page 13 / 34, 16 CN 120983809 A)Switching between input terminal 1 and input terminal 2, and coordinating with the closing or opening of the corresponding grounding switch 25, to continuously monitor the temperature of the patient's body surface detected by all temperature sensors 14 on the electrode pad 10 or to transmit AC signals to the patient. In this embodiment, multiple sets of grounding switches 25 and multiple sets of bidirectional switching switches 26 together form a switching unit (unlabeled).

[0073] In this embodiment, each set of analog-to-digital converters 23 is electrically connected one-to-one to the sampling terminals 1 of multiple bidirectional switching switches 26 in the corresponding set through multiple circuit lines (unlabeled) in the adapter 20, and is configured to receive the temperature detection signal transmitted by the multi-channel dual-purpose signal line 19 of the corresponding electrode pad 10, and convert the temperature detection signal from analog signal to digital signal. Each set of analog-to-digital converters 23 includes multiple detection channels A, B, C, D, E, and each detection channel A, B, C, D, E is used to connect to one corresponding dual-purpose signal line 19 in the multi-channel dual-purpose signal line 19 through the corresponding bidirectional switching switch 26. The number of detection channels in each group of analog-to-digital converters 23 is related to the number of bidirectional switching switches 26 in the corresponding group. The number of detection channels in each group of analog-to-digital converters 23 is related to the number of column groups of electrode units 12 in the corresponding electrode sheet 10. Specifically, the number of detection channels in each group of analog-to-digital converters 23 is equal to the number of bidirectional switching switches 26 in the corresponding group of bidirectional switching switches 26, and is not less than the number of column groups of electrode units 12 in the corresponding electrode sheet 10. As shown in Figure 3, each group of analog-to-digital converters 23 contains a total of 5 detection channels A, B, C, D, and E, which are respectively the first detection channel A, the second detection channel B, the third detection channel C, the fourth detection channel D, and the fifth detection channel E. The first detection channel A is connected to the first dual-purpose signal line 19-1 via the sampling terminal 1 of the first bidirectional switch 26-1; the second detection channel B is connected to the second dual-purpose signal line 19-2 via the sampling terminal 1 of the second bidirectional switch 26-2; the third detection channel C is connected to the third dual-purpose signal line 19-3 via the sampling terminal 1 of the third bidirectional switch 26-3; the fourth detection channel D is connected to the fourth dual-purpose signal line 19-4 via the sampling terminal 1 of the fourth bidirectional switch 26-4; and the fifth detection channel E is connected to the fifth dual-purpose signal line 19-5 via the sampling terminal 1 of the fifth bidirectional switch 26-5. Each detection channel A, B, C, D, and E is used to receive the temperature detection signal collected by the temperature sensor 14 of the electrode unit 12 connected to the corresponding dual-purpose signal line 19. In addition, each detection channel A, B, C, D, and E is connected to the first power module 29, which provides the detection voltage to the corresponding detection channel A, B, C, D, and E, via a corresponding voltage divider resistor 24 in the adapter 20. The first power module 29 provides a DC signal.

[0074] In this embodiment, the first communication unit 27 is configured to acquire digital signals output by multiple sets of analog-to-digital converters 23.The digital signal is then sent to the electric field generator 30. The electric field generator 30 is also configured to control and adjust the voltage, current, or power of the AC signal provided to the plurality of electrode units 12 of the electrode sheet 10 according to the received digital signal. For example, when any of the received digital signals exceeds a preset threshold, it indicates that the temperature detected by at least one temperature sensor 14 in the electrode sheet 10 at the corresponding dielectric element 15 on the human body surface exceeds the preset threshold temperature (e.g., 41°C, 42°C, etc.). At this time, the voltage, current, or power of the AC signal output by the electric field generator 30 can be appropriately reduced to avoid the electrode unit 12 of the electrode sheet 10 becoming too hot when the AC signal is applied, causing low-temperature burns to the patient's skin. The aforementioned preset threshold temperature and preset threshold can be determined according to human safety thresholds. The first communication unit 27 is controlled by the first controller 22 and serially transmits digital signals converted by multiple sets of analog-to-digital converters 23. In this embodiment, the preset temperature threshold can be a value within the range of 36°C to 45°C.

[0075] One end of each of the multiple communication transmission lines 211 embedded in the adapter 20 is connected to the first controller 22, and the other end is electrically connected to the communication line 172, which is electrically connected to the communication pin of the handshake chip 17 of the corresponding electrode 10, through the corresponding wire of the corresponding first cable 13. The ground pin GND of the adapter 22 is also connected to the corresponding wire of the corresponding first cable 13 through a wire electrically connected to the corresponding grounding switch 25, a grounding wire 18 that is connected to both the corresponding wire of the corresponding first cable 13 and the grounding trace 171, and the grounding trace 171 that is shorted to the grounding wire 18 to achieve the connection with the grounding pin of the handshake chip 17 of the corresponding electrode 10. That is, the first controller 22 controls the grounding switch 25 corresponding to the grounding line 18-4 that is short-circuited to the grounding pin of the handshake chip 17 of the electrode 10 to close, and sends a handshake communication signal to the communication line 172 of the electrode 10 through the communication transmission line 211. The first controller 22 determines whether the connection between the electrode 10 and the adapter 20 is normal based on whether the first controller 22 can receive the feedback from the communication line 172 of the electrode 10.

[0076] Referring to FIG4 and FIG5, in this embodiment, the first power module 29 is electrically connected to the second power module 31 of the electric field generator 30 and is configured to supply power to the first controller 22, multiple sets of analog-to-digital converters 23 and the first communication unit 27 of the adapter 20. Each electrode 10 is connected to the adapter 20 with a first connector 40, which is adapted to connect the corresponding electrode 10 to the adapter 20. As shown in Figure 1, the first connector 40 includes a first plug 41 located at the end of the first cable 13 away from the electrode plate 10 and a first socket 42 located on the adapter 20. The first plug 41 and the first socket42 is a press-type spring connector, meaning the first connector 40 uses a connector to connect the adapter 20 to the electrode plate 10. Each first cable 13 has 5 wires electrically connected to the corresponding bidirectional switch 26-1, 26-2, 26-3, 26-4, and 26-5 in the corresponding set of bidirectional switch 26, 4 wires electrically connected to the corresponding grounding switch 25-1, 25-2, 25-3, and 25-4 in the corresponding set of grounding switches 25, and 1 wire electrically connected to both the communication line 172 of the electrode plate 10 and the communication transmission line 211 of the adapter 20. That is, each first connector 40 is electrically connected to the corresponding set of bidirectional switch 26, the corresponding set of grounding switches 25, and the corresponding communication transmission line 211 connected to the first controller 22 through 10 wires; and is connected to the electric field generator 30 through the corresponding AC signal line 28 of the adapter 20.

[0077] A second connector 50 is provided between the adapter 20 and the electric field generator 30. The second connector 50 is adapted to connect the electric field generator 30 to the adapter 20. The adapter 20 also includes a second cable 21 connected to the second connector 50. The second connector 50 includes a second plug 51 located at the end of the second cable 21 away from the first controller 22 and a second socket 52 located on the electric field generator 30. The second plug 51 and the second socket 52 are push-button spring connectors, that is, the second connector 50 connects the adapter 20 and the electric field generator 30 by means of a connector. Each first connector 40, such as X1, Y1, X2, and Y2, is connected to the second connector 50 via a corresponding AC signal line 28. The first connectors 40, such as X1, Y1, X2, and Y2, are respectively connected to a corresponding set of grounding switches 25, a corresponding set of analog-to-digital converters 23, and a corresponding communication transmission line 211. Each first connector 40 is connected to the second connector 50 and the corresponding set of analog-to-digital converters 23 via a corresponding set of bidirectional switching switches 26. Taking four electrode plates 10 as an example, the second cable 21 has eight wires, including four wires 1 to 4 that are electrically connected to the corresponding AC signal lines 28 for transmitting AC signals, one wire 5 that is electrically connected to the data receiving line RX of the first communication unit 27, one wire 6 that is electrically connected to the data transmitting line TX of the first communication unit 27, one wire 7 that is electrically connected to the VCC power line of the first power module 29, and one wire 8 that is electrically connected to the GND line of the first power module 29. The second connector 50 is connected to the first communication unit 27 via a data receiving line RX and a data transmitting line TX. The VCC pin of the second connector 50 is connected to the VCC power supply line of the first power module 29, and the GND pin of the second connector 50 is connected to the first power module 29.The GND line of the source module 29 is connected and grounded, and the VCC pin of the second connector 50 is also connected to the corresponding group of voltage-reducing resistors 24 and the corresponding group of analog-to-digital converters 23 through the VCC power line of the first power module 29.

[0078] Referring to FIG5, the electric field generator 30 includes: a second power module 31, a second controller 32, an AC signal generator 34, a second communication unit 33, and a group of AC signal switches 35. The VCC pin of the second connector 50 is also electrically connected to the VCC power line of the second power module 31, and the GND pin of the second connector 50 is grounded through the GND line of the second power module 31. The second power module 31 is also connected to and supplies power to the second controller 32 and the AC signal generator 34 respectively. The second communication unit 33 is electrically connected to the wire 5 of the second connector 50 through its data receiving line RX and to the wire 6 of the second connector 50 through its data transmitting line TX, thereby realizing information interaction between the electric field generator 30 and the adapter 20. The second controller 32 is also electrically connected to the second communication unit 33, the AC signal generator 34, and a set of AC signal switches 35. The second controller 32 is configured to control the opening and closing of each AC signal switch 35 in the set of AC signal switches 35 and adjust the relevant parameters of the AC signal applied by the AC signal generator 34 according to the relevant digital signals received from the adapter 20 by the second communication unit 33. The relevant parameters include the voltage, current, and power of the AC signal. The AC signal generator 34 is electrically connected to several wires 1, 2, 3, and 4 of the second connector 50 through the set of AC signal switches 35. The set of AC signal switches 35 includes multiple AC signal switches 35, each corresponding to a specific electrode plate 10. Each AC signal switch 35 is electrically connected to a corresponding conductor 1, 2, 3, or 4 in the second connector 50 via an AC signal wiring 36, and is also electrically connected to a corresponding electrode 10 via corresponding conductors 1, 2, 3, or 4 in the second connector 50, to transmit an AC signal to each electrode 10. The AC signal generator 34 is electrically connected to the group of AC signal switches 35 via a set of AC signal wiring 36.

[0079] Specifically, the number of AC signal switches 35 in the electric field generator 30 is related to the number of electrode 10. In this embodiment, the number of AC signal switches 35 is equal to the number of electrode 10, and both are 4. The AC signal switches 35 include a first AC signal switch 35-1, a second AC signal switch 35-2, a third AC signal switch 35-3, and a fourth AC signal switch 35-4, which are electrically connected to conductors 1 to 4 of the second connector 50 respectively. One end of the first AC signal switch 35-1 is connected to the electric field generator 30 via a conductor 1, 2, 3, or 4.The first AC signal connector 36 is electrically connected to the AC signal generator 34. The other end is electrically connected via the first AC signal connector 36-1 to the corresponding AC signal transmission wire 1 in the second connector 50, and via the wire 1 of the second connector 50 to the AC signal line 28 located at port X1 of the adapter 20. The AC signal line 28 at port X1 of the adapter 20 is electrically connected to the first connector 40. The first connector 40 at port X1 of the adapter 20 is electrically connected to the corresponding electrode 10, thereby controlling whether the AC signal generator 34 transmits an AC signal to the electrode 10 electrically connected to port X1 of the adapter 20. The second AC signal switch 35-2 has one end electrically connected to the AC signal generator 34 via the second AC signal connector 36 of the electric field generator 30, and the other end electrically connected via the second AC signal connector 36-2 to the corresponding AC signal transmission wire 2 in the second connector 50, and via the wire 2 of the second connector 50 to the AC signal line 28 located at port Y1 of the adapter 20. The AC signal line 28 at port Y1 of the adapter 20 is electrically connected to the corresponding electrode 10. Signal line 28 is electrically connected to the first connector 40, and the first connector 40 located at port Y1 of adapter 20 is electrically connected to the corresponding electrode 10 to control whether the AC signal generator 34 transmits an AC signal to the electrode 10 electrically connected to port Y1 of adapter 20; one end of the third AC signal switch 35-3 is electrically connected to the AC signal generator 34 through the third AC signal wiring 36-3 of the electric field generator 30, and the other end is connected to the corresponding AC signal transmission wire 3 in the second connector 50 through the AC signal wiring 36-3. The AC signal generator 34 is electrically connected to the AC signal line 28 at port X2 of the adapter 20 via the wire 3 of the second connector 50. The AC signal line 28 at port X2 of the adapter 20 is electrically connected to the first connector 40. The first connector 40 at port X2 of the adapter 20 is electrically connected to the corresponding electrode 10 to control whether the AC signal generator 34 transmits an AC signal to the electrode 10 electrically connected to port X2 of the adapter 20. One end of the fourth AC signal switch 35-4 is electrically connected to the AC signal generator 34 via the fourth AC signal wiring 36-4 of the electric field generator 30. The other end is electrically connected to the corresponding AC signal transmission wire 4 in the second connector 50 via the fourth AC signal wiring 36-4 and to the adapter 20 at port Y2 via the wire 4 of the second connector 50. The AC signal line 28 at port Y2 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 at port Y2 of the adapter 20 is electrically connected to the corresponding electrode plate 10, so as to control whether the AC signal generator 34 transmits AC signal to the electrode plate 10 electrically connected to port Y1 of the adapter 20.

[0080] The working principle of the handshake chip 17 is described in detail below. The handshake chip 17 can be powered by an external energy storage element (not shown).(As shown), when the communication line 172 transmits a high level, it stores electrical energy and releases energy when the communication line 172 transmits a low level, so that the handshake chip 17 obtains sufficient power and operates normally. Optionally, the energy storage element is a capacitor, so that the handshake chip 17 only needs an additional communication core wire to operate normally. The handshake chip 17 is suitable for handshake communication with external devices such as electric field generator 30 or adapter 20 to determine the connection status of each pair of electrode plates 10. After the handshake chip 17 completes handshake communication with adapter 20 and / or electric field generator 30, by combining and configuring the states of bidirectional switching switch 26 and grounding switch 25, the electrode plate 10 can be made to apply an AC signal or perform temperature acquisition. When the electrode 10 needs to acquire or measure temperature, all the bidirectional switching switches 26 on the flexible circuit board 11 of the electrode 10 are located at the sampling end 1. The electric field generator 30 or the adapter manual (page 16 / 34, CN 120983809 A 20) can sequentially close each grounding switch 25 so that the analog temperature signal of the corresponding temperature sensor 14 in each row group is simultaneously sampled by the corresponding temperature sampling point. The analog temperature signal detected by each sampled temperature sensor 14 can also be converted into a signal that can characterize the type of the electrode 10 if the electrode 10 is qualified, or it can be used to characterize whether the electrode 10 has a temperature abnormality.

[0081] Specifically, when the first controller 22 of the adapter 20 receives the handshake signal sent by the electric field generator 30, it controls the corresponding grounding switch 25 connected to the grounding pin of the handshake chip 17 to close, so that the handshake chip 17 is powered on and the handshake signal is sent to the handshake chip 17. The handshake chip 17 sends a feedback signal, and the first controller 22 on the adapter 20 sends the feedback signal of the handshake chip 17 to the second controller 32 of the electric field generator 30 through the second connector 50. The second controller 32 determines whether the corresponding first controller 22 and the handshake chip 17 have completed handshake communication based on the feedback signal of the handshake chip 17. After the handshake communication is completed, the state of each grounding switch 25 and each bidirectional switching switch 26 in the switch unit (unlabeled) on the adapter 20 is configured to transmit AC signals to the dielectric elements of each electrode unit 12 of the electrode sheet 10 or to measure the temperature through the temperature sensor 14 of each electrode unit 12 of the electrode sheet 10. When the electrode 10 is in temperature acquisition mode, the electric field generator 30, through its second controller 32, controls each bidirectional switching switch 26 of the adapter 20 to be in its respective acquisition terminal 1, and sequentially closes each grounding switch 25, so that each detection channel of the corresponding analog-to-digital converter 23 acquires temperature detection signals from each temperature sensor 14 in a row, and performs analog-to-digital conversion on the acquired several temperature analog signals to obtain several AD sampling values, which correspond to digital temperature. The first controller 22 can also control the adapter 20 to acquire temperature detection signals from each temperature sensor 14 in a row.Several AD sampling values ​​are sent to the electric field generator 30 so that, if the electrode 10 is qualified, the electric field generator 30 can identify the type of the corresponding electrode 10 according to the several AD sampling values, and / or, during the transmission of alternating electrical signals to the corresponding electrode 10, determine whether the corresponding electrode 10 has an abnormal temperature according to the several AD sampling values.

[0082] The working principle of the tumor electric field therapy system 100 of this embodiment will be described in detail below with reference to Figures 3 to 5.

[0083] The second controller 32 of the electric field generator 30 controls the grounding switch 25-4 corresponding to the fourth grounding line 18-4 connected to the handshake chip 17 of the electrode 10 to be in a closed state through the first controller 22 of the adapter 20, and sends a handshake signal to the communication line 172 of the electrode 10 through the first controller 22, and determines the connection status between the electrode 10 and the adapter 20 according to whether the feedback of the handshake chip 17 can be received. If the electric field generator 30 receives a feedback signal from the electrode plate 10, it indicates that the connection between the electrode plate 10 and the adapter 20 is normal; then, an AC signal can be applied to the electrode plate 10, or a temperature detection signal can be acquired through the temperature sensor 14 of the electrode plate 10. If the electric field generator 30 does not receive a feedback signal from the electrode plate 10, it indicates that the connection between the electrode plate 10 and the adapter 20 is abnormal, and the second controller 32 of the electric field generator 30 issues a connection abnormality prompt to remind the operator. After the operator handles the issue, the second controller 32 continues to control the first controller 22 of the adapter 20 to send a handshake communication signal to the handshake chip 17 of the electrode plate 10, repeating the above-mentioned operation of judging the connection status of the electrode plate 10 until the connection between the electrode plate 10 and the adapter 20 is normal.

[0084] When the electrode plate 10 is connected normally and the temperature of each electrode unit 12 of a certain electrode plate 10 needs to be detected, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls the sampling terminal 1 of each of the multiple bidirectional switching switches 26 electrically connected to the electrode plate 10 to be turned on and the input terminal 2 to be turned off, so as to disconnect the AC signal applied to the electrode plate 10; at the same time, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls each of the grounding switches 25 electrically connected to the electrode plate 10 to be turned on in sequence. At this time, the temperature detection signal collected by each temperature sensor 14 of each electrode unit 12 in each row of the electrode plate 10 can be collected in sequence in time through the multiple detection channels A, B, C, D, E of the set of analog-to-digital converters 23 corresponding to the electrode plate 10. Each detection channel A, B, C, D, and E of each group of analog-to-digital converters 23 simultaneously only acquires the temperature detection signal of the temperature sensor 14 of the corresponding electrode unit 12 in each row of electrode units 12 of the electrode sheet 10. (See page 17 / 34 of the specification for the aforementioned temperature detection signal. 20 CN)120983809 A can be characterized by voltage values. Of the four grounding switches 25 corresponding to the electrode 10, only one can be on at a time, while the other three are off. All five bidirectional switches 26 of the set of bidirectional switches 26 corresponding to the analog-to-digital converter 23 are switched to their respective sampling terminals 1, so that each dual-purpose signal line 19 of the electrode 10 is electrically connected to the corresponding detection channels A, B, C, D, and E of the corresponding analog-to-digital converter 23. With this configuration, the analog-to-digital converter 23 can acquire the voltage values ​​of all temperature sensors 14 of each electrode unit 12 in the same row group that are short-circuited to one grounding line 18 corresponding to the on-circuit grounding switch 25.

[0085] Specifically, when the first grounding switch 25-1 is closed, the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4 are all open, and the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 are all switched to their respective sampling terminals 1, the temperature sensors 14 of the electrode units 12-1 to 12-5 of the first row group are energized, and the electrode units 12-6 of the remaining row groups are energized. When the temperature sensors 14 of electrode units 12-20 are de-energized, the signal terminals 14-2 of the temperature sensors 14 of electrode units 12-1, 12-6, 12-11, and 12-16 are shorted on the first detection channel A of the analog-to-digital converter 23. Since only the ground terminal 14-1 of the temperature sensor 14 of electrode unit 12-1 is connected to ground, while the ground terminals 14-1 of the temperature sensors 14 of electrode units 12-6, 12-11, and 12-16 are disconnected, and each electrode unit 12 is provided with a diode 16 connected in series with the temperature sensor 14, the other temperature sensors 14 in the first row will not affect the resistance value of the temperature sensor 14 of electrode unit 12-1. Therefore, only the temperature sensor 14 of electrode unit 12-1 is effectively operating on the first detection channel A of the analog-to-digital converter 23, and the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 of electrode unit 12-1. Similarly, the voltage value collected on the second detection channel B of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-2. The voltage value collected on the third detection channel C of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-3. The voltage value collected on the fourth detection channel D of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-4. The voltage value collected on the fifth detection channel E of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-5.

[0086] When the second grounding switch 25-2 is closed, and the first grounding switch 25-1, the third grounding switch 25-3, and the fourth grounding switch 25-4 are all open, and the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 are all switched to their respective sampling terminals 1, the temperature sensors 14 of the electrode units 12-6 to 12-10 in the second row group are energized, while the temperature sensors 14 of the electrode units 12-1 to 12-5 and the electrode units 12-11 to 12-20 in the other row groups are de-energized. The signal terminals 14-2 of the temperature sensors 14 of the electrode units 12-1, 12-6, 12-11, and 12-16 in the first detection channel A of the analog-to-digital converter 23 are shorted. Since only the grounding terminal 14-1 of the temperature sensor 14 of the electrode unit 12-6 is connected... The circuit is grounded, while the grounding terminals 14-1 of the temperature sensors 14 of electrode units 12-1, 12-11, and 12-16 are all disconnected. Each electrode unit 12 has a diode 16 connected in series with the temperature sensor 14. The other temperature sensors 14 in the second row do not affect the resistance of the temperature sensor 14 in electrode unit 12-6. Therefore, only the temperature sensor 14 of electrode unit 12-6 is effectively operating on the first detection channel A of this group of analog-to-digital converters 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 in electrode unit 12-6. Similarly, the voltage value collected on the second detection channel B of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-7. The voltage value collected on the third detection channel C of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-8. The voltage value collected on the fourth detection channel D in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-9. The voltage value collected on the fifth detection channel E in the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-10.

[0087] When the third grounding switch 25-3 is closed, the first grounding switch 25-1, the second grounding switch 25-2 and the fourth grounding switch 25-4 are all open, and the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4 and the fifth bidirectional switching switch 26-5 are all switched to their respective sampling terminals 1, the temperature sensors 14 of electrode units 12-11 to 12-15 in the third row group are energized, and the temperature sensors 14 of electrode units 12-11 to 12-15 in the other rows group are energized.The temperature sensors 14 of electrode units 12-10 and 12-16 to 12-20 are de-energized. The signal terminals 14-2 of the temperature sensors 14 of electrode units 12-1, 12-6, 12-11, and 12-16 are short-circuited on the first detection channel A of the analog-to-digital converter 23. Since only the ground terminal 14-1 of the temperature sensor 14 of electrode unit 12-11 is grounded, the temperature sensors 14 of electrode units 12-1, 12-6, and 12-20 are not connected. The grounding terminal 14-1 of the temperature sensor 14 is disconnected, and each electrode unit 12 is equipped with a diode 16 connected in series with the temperature sensor 14. The other temperature sensors 14 located in the third row do not affect the resistance value of the temperature sensor 14 in electrode unit 12-11. Therefore, only the temperature sensor 14 of electrode unit 12-11 is effectively operating on the first detection channel A of this group of analog-to-digital converters 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 in electrode unit 12-11. Similarly, the voltage value collected on the second detection channel B of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-12. The voltage value collected on the third detection channel C of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-13. The voltage value collected on the fourth detection channel D of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-14. The voltage value collected on the fifth detection channel E in this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-15.

[0088] When the fourth grounding switch 25-4 is closed, the first grounding switch 25-1, the second grounding switch 25-2 and the third grounding switch 25-3 are all open, and the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4 and the fifth bidirectional switching switch 26-5 are all switched to their respective sampling terminals 1, the temperature sensors 14 of electrode units 12-16 to 12-20 in the fourth row group are powered on, and the temperature sensors 14 of electrode units 12-1 to 12-15 in the other rows are de-powered. The signal terminals 14- of the temperature sensors 14 of electrode units 12-1, 12-6, 12-11 and 12-16 in the first detection channel A of this group of analog-to-digital converters 23 are short-circuited. 2. Because only the grounding terminal 14-1 of the temperature sensor 14 of electrode unit 12-16 is connected to ground, while the grounding terminals 14-1 of the temperature sensors 14 of electrode units 12-1, 12-6, and 12-11 are disconnected, and each electrode unit 12...Each of the four analog-to-digital converters (ADCs) is equipped with a diode 16 connected in series with the temperature sensor 14. The other temperature sensors 14 in the fourth row do not affect the resistance of the temperature sensors 14 in electrode units 12-16. Therefore, only the temperature sensors 14 in electrode units 12-16 are effectively operating on the first detection channel A of this ADC group. At this time, the temperature detection signal (voltage value) acquired by the first detection channel A is the voltage value of the temperature sensors 14 in electrode units 12-16. Similarly, the voltage value acquired on the second detection channel B of this ADC group is the voltage value of the temperature sensors 14 in electrode units 12-17. The voltage value acquired on the third detection channel C of this ADC group is the voltage value of the temperature sensors 14 in electrode units 12-18. The voltage value acquired on the fourth detection channel D of this ADC group is the voltage value of the temperature sensors 14 in electrode units 12-19. The voltage value acquired on the fifth detection channel E of this ADC group is the voltage value of the temperature sensors 14 in electrode units 12-20. Therefore, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 can acquire the temperature detection signals of the temperature sensors 14 of all electrode units 12 of a certain electrode plate 10 by controlling a set of bidirectional switching switches 26 and a set of grounding switches that are all electrically connected to a certain electrode plate 10. Similarly, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 of other electrode plates 10 can be obtained.

[0089] The first controller 22, multiple sets of analog-to-digital converters 23, and multiple sets of bidirectional switching switches 26 can be automatically operated by pre-programmed program code (page 19 / 34, CN 120983809 A). For example, the first controller 22 first controls all bidirectional switching switches 26 in the corresponding set to switch to sampling terminal 1, so that all sampling terminals 1 of these bidirectional switching switches 26 are turned on and all input terminals 2 are turned off, so that each dual-purpose signal line 19 of the corresponding electrode plate 10 is electrically connected to the corresponding set of analog-to-digital converters 23. Then, it closes the first grounding switch 25-1 in the corresponding set of grounding switches 25, and opens the remaining second grounding switches 25-2, third grounding switches 25-3 to fourth grounding switches 25-4 in the set of grounding switches 25. During this period, each detection channel A, B, C of the set of analog-to-digital converters 23 is connected. D and E acquire the temperature detection signals of each temperature sensor 14 of each electrode unit 12 located in the first row of the corresponding electrode sheet 10, convert them into digital signals, and store them in a separately set memory. Then, after a preset interval, the first controller 22 closes the second grounding switch 25-2 in the group of grounding switches 25, and opens the first grounding switch 25-1, the third grounding switch 25-3, and the fourth grounding switch 25-4 in the group of grounding switches 25. During this period, each detection channel of the analog-to-digital converter 23 in the group remains open.Temperature detection signals from each temperature sensor 14 of each electrode unit 12 located in the second row group are obtained via channels A, B, C, D, and E. By sequentially and individually activating each grounding switch 25 in this group, temperature detection signals from all temperature sensors 14 located in each row group of the electrode plate 10 can be obtained. Similarly, this operation yields temperature detection signals from all temperature sensors 14 on at least one pair of electrode plates 10.

[0090] The tumor electric field therapy system 100 of this application can achieve real-time and comprehensive monitoring of the temperature of all electrode units 12 on the electrode sheet 10 without increasing the weight of the electrode sheet 10 or the number of wire cores of the first cable 13 electrically connected to the electrode sheet 10. It can then determine whether the electrode sheet 10 is qualified based on the obtained temperature detection signal; or determine whether the temperature sensor 14 of the electrode sheet 10 is faulty or abnormal based on the obtained temperature detection signal, and determine whether the electrode sheet 10 needs to be replaced based on the number of faulty or abnormal temperature sensors 14; or, if the electrode sheet is qualified, identify the electrode sheet type based on the obtained temperature detection signal; or, if the electrode sheet is qualified, determine whether the electrode unit 12 of the electrode sheet 10 is overheated based on the obtained temperature detection signal, and then control the alternating electrical signal applied to the electrode sheet 10 or the corresponding column of electrode units 12 of the electrode sheet 10, thereby avoiding low-temperature burns to the patient's body surface during tumor treatment through the electrode sheet 10. Furthermore, the flexible circuit board 11 of the electrode sheet 10 of this application is electrically connected to the dielectric element 15 of the same electrode unit 12 and the signal terminal 14-2 of the temperature sensor 14 through the same dual-purpose signal line 19. This allows for the transmission of both AC signals and DC signals for temperature signal acquisition, as well as the acquired temperature detection signal, via the dual-purpose signal line 19. Simultaneously, it significantly reduces the number of conductive traces (grounding line 18, dual-purpose signal line 19) laid on it, reducing the wiring difficulty of the flexible circuit board 11, simplifying the manufacturing process, reducing the weight of the flexible circuit board 11, and lowering manufacturing costs. The electrode sheet 10 of this application can also switch between applying AC signals for tumor treatment and transmitting DC signals for temperature acquisition and transmitting the acquired temperature detection signal through a combination of a grounding switch 25 electrically connected to the grounding line 18 and a bidirectional switching switch 26 electrically connected to the dual-purpose signal line 19.

[0091] When the electrode pads 10 are properly connected and it is necessary to apply an AC signal to the patient through each electrode unit 12 of a certain electrode pad 10, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls all the grounding switches 25 in a set of grounding switches 25 corresponding to that electrode pad 10 to be disconnected, and at the same time controls a set of double-phase grounding switches corresponding to that electrode pad 10 to be disconnected.All bidirectional switches 26 in the switching switch 26 are switched to their respective input terminals 2, so that the sampling terminals 1 of all bidirectional switches 26 are disconnected and the input terminals 2 are all turned on. This enables all dual-purpose signal lines 19 of the electrode plate 10 to be electrically connected to the AC signal line 28 corresponding to the electrode plate 10 in the adapter 20, thereby transmitting the AC signal to each electrode unit 12 of the electrode plate 10. When the temperature detection signal of the temperature sensor 14 of all electrode units 12 of the electrode plate 10 is much lower than the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 controls the AC signal generator 34 through its second controller 32 to continue generating AC signals with increased or unchanged voltage or current amplitude. (Instruction manual 20 / 34 pages 23 CN 120983809 A) Then, the AC signal is transmitted to the corresponding counter electrode 10 via the corresponding AC signal line 28 of the adapter 20, so that the counter electrode 10 continues to be applied with an AC signal; when the temperature detection signal of the temperature sensor 14 of all electrode units 12 of the detected electrode 10 is lower than but close to the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 can reduce the voltage or current of the AC signal generated by the AC signal generator 34 through the second controller 32, thereby reducing the voltage or current of the AC signal applied to the counter electrode 10; when the temperature detection signal of the temperature sensor 14 of the electrode unit 12 of a certain electrode 10 is detected to be greater than the preset temperature threshold, the electric field generator 30 controls the AC signal switch 35 electrically connected to the electrode 10 to disconnect through the second controller 32, so as to stop applying the AC signal to the electrode 10; or the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 controls a set of bidirectional switching switches electrically connected to the electrode 10 to disconnect. All bidirectional switches 26 in switch 26 switch from their input terminal 2 to their sampling terminal 1. That is, all bidirectional switches 26 in a set of bidirectional switches 26 electrically connected to the electrode 10 have their sampling terminals 1 fully open and their input terminals 2 fully open, thereby stopping the application of alternating electrical signals to the electrode 10 for a certain period of time. Alternatively, when the temperature detection signal of the temperature sensor 14 of an electrode unit 12 on a certain electrode 10 is detected to be greater than a preset temperature threshold, the second controller 32 of the electric field generator 30 controls the AC signal switch 35 electrically connected to the electrode 10 to continue to be open. The second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 controls a bidirectional switch 26 electrically connected to the electrode unit 12 of the electrode 10 to switch from its input terminal 2 to its sampling terminal 1. The second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 simultaneously controls the bidirectional switches 26 electrically connected to the electrode unit 12 of the electrode 10 to switch from their input terminals 2 to their sampling terminals 1.The input terminals 2 of the remaining bidirectional switching switches 26 electrically connected to electrode units 12 in different columns of the electrode unit 12 remain electrically connected. This stops applying AC signals to all electrode units 12 in the column where the temperature detection signal of the electrode plate 10 exceeds a preset temperature threshold, while continuing to apply AC signals to the remaining column electrode units 12 where the temperature detection signal of the electrode plate 10 does not exceed the preset temperature threshold. This achieves a control method for regional application of AC signals based on temperature detection signals in the tumor electric field therapy system 100. When applying AC signals, all grounding switches 25 are disconnected.

[0092] In this embodiment, the grounding switch 25, which is electrically connected to the multiple grounding lines 18 of the electrode 10, and the bidirectional switching switch 26, which is electrically connected to the multiple dual-purpose signal lines 19 of the electrode 10, are both located in the adapter 20. However, in other embodiments, the grounding switch 25, which is electrically connected to the grounding line 18, and the bidirectional switching switch 26, which is electrically connected to the dual-purpose signal lines 19, may also be located on the electrode 10 or in the electric field generator 30, which will not be described in detail here. In addition, the analog-to-digital converter 23 located in the adapter 20 may also be located in the electric field generator 30 and directly controlled by the second controller 32.

[0093] This application also provides other embodiments of the electrode 10. The main difference between the multiple embodiments is the number of electrode units 12 and / or the circuit distribution of the electrode units 12, which will be described below.

[0094] Figure 6 is a circuit connection diagram of the tumor electric field therapy system for the second embodiment of this application, showing the circuit connection diagram between the electrode 10D of the second embodiment and the adapter 20 of the first embodiment shown in Figure 1. The following circuit description uses the electrode sheet 10D in the second embodiment as an example. The difference between the electrode sheet 10D and the electrode sheet 10 in the first embodiment lies in the number and circuit arrangement of the electrode units 12. The electrode sheet 10D in this embodiment has 13 of the aforementioned electrode units 12. In terms of electrical connection, the flexible circuit board 11D of the electrode sheet 10D arranges these 13 electrode units 12 in three rows and five columns, with each of the two rows having 5 electrode units 12 and the remaining row having 3 electrode units 12. The flexible circuit board 11D of the electrode sheet 10D embeds 3 grounding lines 18, 5 dual-purpose signal lines 19, 1 grounding trace 171 connected to both the grounding pin of the handshake chip 17 and any of the grounding lines 28, and 1 communication line 172 connected to the communication pin of the handshake chip 17. Each grounding wire 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the corresponding row group. Each dual-purpose signal line 19 is used to short-circuit the dielectric of each electrode unit 12 in each column group.The signal terminals 14-2 of the electrical component 15 and each temperature sensor 14 are used to receive temperature detection signals or transmit AC signals. A grounding line 18 connected to the grounding trace 171 also grounds the grounding pin of the handshake chip 17.

[0095] The three grounding lines 18 of the flexible circuit board 11D are the first grounding line 18-1, the second grounding line 18-2, and the third grounding line 18-3. In the three rows of the electrode sheet 10D, the first row includes electrode units 12-1 to 12-5, the second row includes electrode units 12-6 to 12-10, and the third row includes electrode units 12-11 to 12-13. Specifically, the first grounding wire 18-1 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-1 to electrode unit 12-5 in the first row group; the second grounding wire 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-6 to electrode unit 12-10 in the second row group; the third grounding wire 18-3 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-11 to electrode unit 12-13 in the third row group and is also used to ground the grounding pin of the handshake chip 17 through the grounding trace 171 connected to the grounding pin of the handshake chip 17. In short, each grounding wire 18 short-circuits and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group, and one of the grounding wires 18 also short-circuits and grounds the grounding pin of the handshake chip 17.

[0096] The five dual-purpose signal lines 19 of the electrode sheet 10D include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4 and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-1, 12-6, and 12-11) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-2, 12-7, and 12-12) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-3, 12-8, and 12-13) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is simultaneously connected to the dielectric element 15 of each of the two electrode units 12 (electrode units 12-4 and 12-9) and the signal terminal 14-2 of their respective temperature sensors 14; the fifth dual-purpose signal line...One end of signal line 19-5 is simultaneously connected to the dielectric element 15 of each of the two electrode units 12 (electrode unit 12-5 and electrode unit 12-10) and the signal terminal 14-2 of their respective temperature sensors 14. In short, each dual-purpose signal line 19 short-circuits the dielectric element 15 and the signal terminal 14-2 of each electrode unit 12 located in the corresponding column group in parallel and is used to connect to the adapter 20.

[0097] The first grounding switch 25-1, the second grounding switch 25-2 and the third grounding switch 25-3 on the adapter 20 are electrically connected to the first grounding wire 18-1, the second grounding wire 18-2 and the third grounding wire 18-3 of the electrode plate 10D respectively through the first connector 40D, and the fourth grounding switch 25-4 is in an idle and open state. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4, and the fifth bidirectional switch 26-5 on the adapter 20 are electrically connected, respectively, to the first dual-purpose signal lines 19-1, 19-2, 19-3, 19-4, and 19-5 of the electrode plate 10D via the first connector 40D. A communication transmission line 211 on the adapter 20 is electrically connected to the communication line 172, which is connected to the communication pin of the handshake chip 17 of the electrode plate 10D.

[0098] The tumor electric field therapy system formed by the electrode 10D, the adapter 20 and the electric field generator 30 operates in the same way as the aforementioned tumor electric field therapy system 100. The second controller 32 of the electric field generator 30 sends a handshake communication signal to the first controller 22 of the adapter 20, and closes the third grounding switch 25-3, which is electrically connected to the handshake chip 17 of the electrode 10, through the first controller 22 of the adapter 20 or by directly controlling it. The handshake chip 17 is powered on. At this time, the first controller 22 sends a handshake communication signal to the handshake chip, and confirms that the electrode 10 is connected normally after receiving the feedback signal from the handshake chip 17. If no feedback signal is received from the handshake chip 17, it is confirmed that the electrode 10 is connected abnormally. When the electrode plate 10 is properly connected, the electric field transmitter 30 or the adapter 20 controls 1) all grounding switches 25 to be completely disconnected and the input terminals 2 and sampling terminals 1 of all bidirectional switching switches 26 to be turned on and off, so that all dual-purpose signal lines 19 and AC signal lines 28 are connected. At this time, all electrode units 12 of the electrode plate 10 can apply AC signals; 2) the sampling terminals 1 and input terminals 2 of all bidirectional switching switches 26 are turned on and off, and each grounding switch 25 is turned on in sequence, so that the temperature detection signals of the temperature sensors 14 of each electrode unit 12 of each row group of the electrode plate 10 can be obtained in sequence. Among them, no operation is required for the grounding switches 25 that are in the idle disconnected state.

[0099] Referring to FIG7, which is a circuit connection diagram of the tumor electric field therapy system according to the third embodiment of this application, the diagram shows a circuit connection diagram between the electrode plate 10E of the third embodiment and the adapter 20 shown in FIG1. ​​The electrode plate 10E is provided with 13 electrode units 12, just like the electrode plate 10D in the second embodiment, but the specific circuit arrangement is different. The flexible circuit board 11E of the electrode plate 10E also arranges these 13 electrode units 12 in three rows and five columns in the circuit, except that each of the two rows has 4 electrode units 12, and the remaining row has 5 electrode units 12. The flexible circuit board 11E of the electrode plate 10E is also embedded with 3 ground lines 18, 5 dual-purpose signal lines 19, 1 ground trace 171 that is connected to the ground pin of the handshake chip 17 and any ground line 28 at the same time, and 1 communication line 172 that is connected to the communication pin of the handshake chip 17. Each grounding wire 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the corresponding row group. Each dual-purpose signal line 19 is used to short-circuit the dielectric element 15 of each electrode unit 12 and the signal terminal 14-2 of each temperature sensor 14 in each column group, for receiving temperature detection signals or transmitting AC signals. One grounding wire 18 connected to the grounding trace 171 also grounds the grounding pin of the handshake chip 17.

[0100] The three grounding wires 18 of the electrode sheet 10E include a first grounding wire 18-1, a second grounding wire 18-2 and a third grounding wire 18-3. The first row group includes electrode units 12-1 to 12-4, the second row group includes electrode units 12-5 to 12-8, and the third row group includes electrode units 12-9 to 12-13. Specifically, the first grounding wire 18-1 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-1 to electrode unit 12-4 in the first row group; the second grounding wire 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-5 to electrode unit 12-8 in the second row group; and the third grounding wire 18-3 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-9 to electrode unit 12-13 in the third row group, and grounds the grounding pin of the handshake chip 17 through the grounding trace 171 connected to the grounding pin of the handshake chip 17. In short, each grounding wire 18 short-circuits and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in each row group, and one grounding wire 18 also short-circuits and grounds the grounding pin of the handshake chip 17.

[0101] The five dual-purpose signal lines 19 of the electrode sheet 10E include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. The first dual-purpose signal line 19-1One end of the first dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode unit 12-1, electrode unit 12-5, and electrode unit 12-9) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode unit 12-2, electrode unit 12-6, and electrode unit 12-10) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the electrode unit 12-3, electrode unit 12-5, and electrode unit 12-9. Each of the three electrode units 12 (electrode units 12-7, 12-11) has its dielectric element 15 and its temperature sensor 14 signal terminal 14-2 connected to both the dielectric element 15 and the signal terminal 14-2 of the temperature sensor 14 of each of the three electrode units 12 (electrode units 12-4, 12-8, 12-12). One end of the fifth dual-purpose signal line 19-5 is simultaneously connected to both the dielectric element 15 and the signal terminal 14-2 of the temperature sensor 14 of the electrode unit 12-13. In short, each dual-purpose signal line 19 short-circuits the dielectric element 15 and the signal terminal 14-2 of the temperature sensor 14 of each electrode unit 12 located in the corresponding column group and connects them to the adapter 20 (pages 23 / 34 of the adapter manual, CN 120983809 A).

[0102] The first grounding switch 25-1, the second grounding switch 25-2, and the third grounding switch 25-3 on the adapter 20 are electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, and the third grounding wire 18-3 of the electrode plate 10E respectively via the first connector 40E. The fourth grounding switch 25-4 is in an idle and disconnected state. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 on the adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5 of the electrode plate 10E respectively via the first connector 40E. A communication transmission line 211 on the adapter 20 is electrically connected to a communication line 172 connected to the communication pin of the handshake chip 17 of the electrode 10E.

[0103] The tumor electric field therapy system formed by the electrode 10E, the adapter 20, and the electric field generator 30 operates in the same way as the aforementioned tumor electric field therapy system 100. After the electric field generator 30 controls the adapter 20 to complete the handshake communication with the handshake chip 17 of the electrode 10E and confirms that the electrode 10E is connected normally, when all grounding switches 25 are open and all bidirectional switching switches are closed,When input terminal 2 of switch 26 is turned on and sampling terminal 1 is turned off, all dual-purpose signal lines 19 and AC signal lines 28 are turned on, and all electrode units 12 can be given AC signals; when sampling terminal 1 of all bidirectional switching switches 26 is turned on and input terminal 2 is turned off, the temperature detection signals of temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25 in sequence. Among them, no operation is required for grounding switches 25 in the idle and disconnected state.

[0104] Referring to FIG8, the electrode sheet 10F of the fourth embodiment has 13 electrode units 12, just like the electrode sheet 10D of the third embodiment, but the specific circuit layout is different. The flexible circuit board 11F of electrode sheet 10F arranges these 13 electrode units 12 in four rows and four columns on the circuit, with three rows each having 4 electrode units 12 and the remaining row having 1 electrode unit 12. The electrode plate 10F includes four grounding lines 18, four dual-purpose signal lines 19, one grounding trace 171 that is simultaneously connected to the grounding pin of the handshake chip 17 and any one of the grounding lines 28, and one communication line 172 that is connected to the communication pin of the handshake chip 17. Each grounding line 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the corresponding row group. Each dual-purpose signal line 19 is short-circuited to the dielectric element 15 of each electrode unit 12 in each column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals. One grounding line 18 connected to the grounding trace 171 also grounds the grounding pin of the handshake chip 17.

[0105] The four grounding lines 18 of the electrode plate 10F include a first grounding line 18-1, a second grounding line 18-2, a third grounding line 18-3 and a fourth grounding line 18-4. The first row group includes electrode units 12-1 to 12-4, the second row group includes electrode units 12-5 to 12-8, the third row group includes electrode units 12-9 to 12-12, and the fourth row group includes electrode unit 12-13. Specifically, the first grounding wire 18-1 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-1 to 12-4 in the first row group; the second grounding wire 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-5 to 12-8 in the second row group; the third grounding wire 18-3 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-9 to 12-12 in the third row group; and the fourth grounding wire 18-4 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-13 in the fourth row group. The fourth grounding line 18-4 is also connected to the grounding trace 171, which is connected to the grounding pin of the handshake chip 17. In short, each grounding...Line 18 shorts and grounds the ground terminals 14-1 of the temperature sensors 14 of all electrode units 12 in each row group, and one of the grounding lines 18 also shorts and grounds the ground pin of the handshake chip 17.

[0106] The four dual-purpose signal lines 19 of the electrode sheet 10F include the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3 and the fourth dual-purpose signal line 19-4. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the four electrode units 12 (electrode units 12-1, 12-5, 12-9, and 12-13) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-2, 12-6, and 12-10) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-3, 12-7, and 12-11) and their respective temperature sensors 14. The signal terminal 14-2; one end of the fourth dual-purpose signal line 19-4 is simultaneously connected to the signal terminal 14-2 of the dielectric element 15 of each of the three electrode units 12 (electrode unit 12-4, electrode unit 12-8, and electrode unit 12-12) and the signal terminal 14-2 of their respective temperature sensors 14. In short, each dual-purpose signal line 19 short-circuits the signal terminals 14-2 of the dielectric element 15 and the temperature sensors 14 of each electrode unit 12 located in the same column group and uses them to connect to the adapter 20.

[0107] The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4 on the adapter 20 are electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, the third grounding wire 18-3, and the fourth grounding wire 18-4 of the electrode plate 10F respectively through the first connector 40F. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, and the fourth bidirectional switching switch 26-4 on the adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, and the fourth dual-purpose signal line 19-4 respectively via the first connector 40F. The fifth bidirectional switching switch 26-5 is in an idle and disconnected state. A communication transmission line 211 on the adapter 20 is electrically connected to the communication line 172 connected to the communication pin of the handshake chip 17 of the electrode 10F.

[0108] The working mode of the tumor electric field therapy system formed by the electrode 10F, the adapter 20, and the electric field generator 30 is the same as the previousSimilar to the tumor electric field therapy system 100, after the handshake communication is completed with the first controller 22 of the adapter 20 through the handshake chip 17 and the connection of the electrode 10F is confirmed to be normal, when all grounding switches 25 are all open and the input terminals 2 of all bidirectional switching switches 26 are on, all dual-purpose signal lines 19 and AC signal lines 28 are on, and all electrode units 12 are connected to AC signals; when the sampling terminals 1 of all bidirectional switching switches 26 are on, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25 in sequence. Among them, no operation is required for the grounding switches 25 and / or the bidirectional switching switches 26 that are idle.

[0109] Referring to FIG9, it is a schematic diagram of the circuit connection between the electrode and the adapter 20 in another embodiment of the tumor electric field therapy system of this application. In terms of electrical connection, the difference between the electrode 10H in this embodiment and the aforementioned electrode is also in the number of electrode units 12 and the arrangement of the electrode units 12 in the circuit connection. In this embodiment, the electrode sheet 10H has 9 electrode units 12. The flexible circuit board 11H of the electrode sheet 10H arranges these 9 electrode units 12 in two rows and five columns in the circuit connection, with one row having 5 electrode units 12 and the other row having 4 electrode units 12. The flexible circuit board 11H of the electrode sheet 10H is embedded with 2 grounding lines 18, 5 dual-purpose signal lines 19, 1 grounding trace 171 that is connected to the grounding pin of the handshake chip 17 and any grounding line 28, and 1 communication line 172 that is connected to the communication pin of the handshake chip 17. Each grounding line 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the corresponding row group. One grounding line 18 is also used to ground the grounding pin of the handshake chip 17. Each dual-purpose signal line 19 is short-circuited to the dielectric element 15 of each electrode unit 12 in each column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals.

[0110] The two grounding lines 18 of the electrode sheet 10H are the first grounding line 18-1 and the second grounding line 18-2. In the two rows of the electrode sheet 10H, the first row includes electrode units 12-1 to 12-5, and the second row includes electrode units 12-6 to 12-9. Specifically, the first grounding line 18-1 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-1 to 12-5 in the first row; the second grounding line 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-6 to 12-9 in the second row, and simultaneously grounds the grounding pin of the handshake chip 17 through the grounding trace 171 connected to the grounding pin of the handshake chip 17. In short, each grounding line specification is on pages 25 / 34, page 28, CN.120983809 A 18 short-circuit and ground the ground terminals 14-1 of the temperature sensors 14 of all electrode units 12 in each row group, and one of the ground lines 18 also grounds the ground pin of the handshake chip 17.

[0111] The five dual-purpose signal lines 19 of the electrode sheet 10H include the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4 and the fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the two electrode units 12 (electrode unit 12-1 and electrode unit 12-6) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the two electrode units 12-2 and electrode unit 12-7 and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric element 15 of each of the two electrode units 12-3 and electrode unit 12-8 and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is simultaneously connected to the dielectric element 15 of each of the two electrode units 12-4 and electrode unit 12-9 and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the fifth dual-purpose signal line 19-5 is connected to the dielectric element 15 of the electrode unit 12-5 and the signal terminal 14-2 of the temperature sensor 14. In short, each dual-purpose signal line 19 shorts in parallel the signal terminals 14-2 of the dielectric elements 15 and temperature sensors 14 of each electrode unit 12 located in the corresponding column group and connects them to the adapter 20.

[0112] The first grounding switch 25-1 and the second grounding switch 25-2 on the adapter 20 are electrically connected to the first grounding wire 18-1 and the second grounding wire 18-2 of the electrode plate 10H respectively through the first connector 40H, and the third grounding switch 25-3 and the fourth grounding switch 25-4 are in an idle and disconnected state. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 on the adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5 respectively via the first connector 40H. A communication transmission line 211 on the adapter 20 is electrically connected to the communication line 172 connected to the communication pin of the handshake chip 17 of the electrode 10H.

[0113] The working mode of the tumor electric field therapy system formed by the electrode 10H, the adapter 20, and the electric field generator 30 is the same as that of the previous...Similar to the tumor electric field therapy system 100, after the electric field generator 30 controls the adapter 20 to complete handshake communication with the handshake chip 17 of the electrode 10E and confirms that the electrode 10E is connected normally, when all grounding switches 25 are open and the input terminals 2 and sampling terminals 1 of all bidirectional switching switches 26 are open, all dual-purpose signal lines 19 and AC signal lines 28 are connected, and all electrode units 12 are connected to AC signals; when the sampling terminals 1 and input terminals 2 of all bidirectional switching switches 26 are open, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25 in sequence. No operation is required for the grounding switches 25 that are in an idle or open state.

[0114] In the preceding embodiments, the number of grounding switches 25 corresponding to each electrode piece 10, 10D, 10E, 10F, and 10H of the adapter 20 is fixed at 4, and the number of bidirectional switching switches 26 corresponding to each electrode piece 10, 10D, 10E, 10F, and 10H is fixed at 5. This allows for the application of various electrode pieces 10, 10D, 10E, 10F, and 10H with different numbers of electrode units 12. However, in some cases, grounding switches 25 and / or bidirectional switching switches 26 may be in an idle or disconnected state, which can complicate the program control. To simplify the control program, specific adapters can be provided corresponding to the number of grounding wires 18 and the number of dual-purpose signal lines 19 of the electrode pieces to avoid the occurrence of grounding switches 25 and / or bidirectional switching switches 26 in an idle or disconnected state, thus facilitating program control. That is, in other embodiments, the number of grounding switches 25 in each group of grounding switches 25 provided on the adapter 20 can be set according to the number of rows of each electrode unit 12 of the corresponding electrode sheet in the circuit connection, or according to the number of grounding wires 18 on the flexible circuit board of the corresponding electrode sheet; the number of bidirectional switching switches 26 in each group of bidirectional switching switches 26 provided on the adapter 20 can be set according to the number of columns of each electrode unit 12 of the corresponding electrode sheet in the circuit connection, or according to the number of dual-purpose signal lines 19 on the flexible circuit board of the corresponding electrode sheet (page 26 / 34, CN 120983809 A). Preferably, the number of grounding switches 25 in each group of grounding switches 25 of the adapter 20 is equal to the number of rows of each electrode unit 12 of the corresponding electrode sheet in the circuit connection, or equal to the number of grounding wires 18 on the flexible circuit board of the corresponding electrode sheet; the number of bidirectional switching switches 26 in each group of bidirectional switching switches 26 provided on the adapter 20 is equal to the number of columns of each electrode unit 12 of the corresponding electrode sheet in the circuit connection, or equal to the number of dual-purpose signal lines 19 on the flexible circuit board of the corresponding electrode sheet

[0115] The present invention also provides a temperature detection method for electrode sheet 10 in a tumor electric field therapy system 100. Referring to FIG10, the method includes:

[0116] Step S10: The connector 20 performs handshake communication with the handshake chip 17 of the electrode 10 to determine the connection status of the corresponding electrode 10.

[0117] Step S20: When the electrode 10 and the connector 20 are normally connected, the connector 20 configures the switching status of each grounding switch 25 and each bidirectional switching switch 26 corresponding to the electrode 10 so that the temperature signals detected by each temperature sensor 14 in each row group are sampled sequentially through each corresponding temperature sampling point.

[0118] The present invention also provides an electrode type identification method. The electrode type identification is performed when all temperature sensors of the electrode are normally connected. In addition to the above steps S10 and S20, the method also includes:

[0119] Step S30: Identify the type of the corresponding electrode 10 according to the temperature signals detected by all temperature sensors 14 of the corresponding electrode 10.

[0120] The temperature signals detected by all temperature sensors 14 of the corresponding electrode 10 sampled in step S30 are temperature analog signals. Step S30 specifically includes the following steps:

[0121] Step S301: Perform digital-to-analog conversion on all sampled temperature analog signals to obtain several AD sampling values;

[0122] Step S302: Determine the number of electrode units 12 of the corresponding electrode sheet 10 according to the several AD sampling values;

[0123] Step S303: Determine the type of the corresponding electrode sheet 10 according to the number of electrode units 12.

[0124] The present invention also provides a method for judging abnormal temperature of an electrode sheet. The judgment of abnormal temperature of an electrode sheet is performed during the process of applying an alternating current signal to each electrode unit of the electrode sheet for tumor electric field therapy. In addition to the above steps S10 and S20, the method also includes the following steps:

[0125] Step S40: Judge whether the corresponding electrode sheet 10 has a temperature abnormality based on the temperature signals detected by all temperature sensors of the sampled corresponding electrode sheet.

[0126] Step S40 specifically includes the following steps:

[0127] Step S401: Compare all sampled temperature signals with a preset temperature threshold;

[0128] Step S402: Determine whether the electrode sheet has a temperature abnormality based on the comparison result.

[0129] The comparison result in step S402 includes temperature signals less than the preset temperature threshold and temperature signals greater than or equal to the preset temperature threshold. The determination of temperature abnormality is as follows: when there is a temperature signal greater than or equal to the preset temperature threshold among all sampled temperature signals, the electrode sheet temperature is determined to be abnormal; when all sampled temperature signals are less than the preset temperature threshold, the electrode sheet temperature is determined to be normal. The preset temperature threshold is 39℃-44℃, preferably 41℃.

[0130] The present invention also includes an alternating electrical signal adjustment method, which includes steps S10 and S20, and also includes...Includes: adjusting the alternating electrical signal applied to the corresponding electrode plate according to the temperature signals detected by all temperature sensors of the corresponding electrode plate. The adjustment is to adjust the magnitude of the voltage, current or power of the alternating electrical signal.

[0131] Referring to FIG11, the present invention also provides an electric field control method applied to the tumor electric field therapy system 100, the electric field control method including the following steps:

[0132] In step 101, the tumor electric field therapy system 100 is connected. Specification 27 / 34 pages 30 CN 120983809 A

[0133] Specifically, the four electrode plates 10 are respectively connected to the adapter 20, the adapter 20 is connected to the electric field generator 30, and the electric field generator 30 is connected to the appropriate power supply.

[0134] In step 102, it is detected whether the user issues a command to turn on the electric field. If no command to turn on the electric field is detected, step 102 is repeated; if a command to turn on the electric field is detected, step 103 is entered.

[0135] In step 103, after the electric field generator 30 of the tumor electric field therapy system 100 sends a handshake signal to the electrode 10 connected to the X1 port through the second connector 50, the adapter 20, and the first connector 40 connected to the X1 port, the first controller 22 of the adapter 20 receives the feedback signal from the electrode 10 at the X1 port through the corresponding communication transmission line 211 and determines whether the handshake is successful; if it fails, proceed to step 105; if it succeeds, proceed to step 106.

[0136] This determination step can occur in the adapter 20 or the electric field generator 30. In this embodiment, the determination step occurs in the adapter 20. Specifically, when the electrode 10 at the X1 port is connected normally, its handshake chip 17 can receive the handshake request signal from the electric field generator 30 and feed back the handshake status to the first controller 22 of the adapter 20. The first controller 22 determines that the handshake is successful. Conversely, if the electrode 10 at the X1 port is abnormally connected, the first controller 22 of the adapter 20 will not receive the feedback signal from its handshake chip 17, and the first controller 22 will determine that the handshake has failed.

[0137] In step 105, the tumor electric field therapy system 100 issues an alarm due to the handshake failure, and then proceeds to step 101.

[0138] In step 106, after the electric field generator 30 sends a handshake signal to the electrode 10 connected to the X2 port through the second connector 50, the adapter 20, and the first connector 40 connected to the X2 port, the first controller 22 on the adapter 20 receives the feedback signal from the electrode 10 at the X2 port through the corresponding communication transmission line 211, and determines whether the handshake has passed. If it has not passed, proceed to step 105; if it has passed, proceed to step 107.

[0139] This determination step can occur in the adapter 20 or the electric field generator 30. In this embodiment, this determination step occurs in the adapter 20 or the electric field generator 30.The handshake is generated in the adapter 20. Specifically, when the electrode 10 at the X2 port is connected normally, its handshake chip 17 can receive the handshake request signal from the electric field generator 30 and feed back the handshake status to the first controller 22 of the adapter 20. The first controller 22 judges that the handshake is successful. Conversely, when the electrode 10 at the X2 port is connected abnormally, the first controller 22 of the adapter 20 does not receive the feedback signal from its handshake chip 17, and the first controller 22 judges that the handshake has failed.

[0140] In step 107, after the electric field generator 30 sends a handshake signal to the electrode 10 connected to the Y1 port through the second connector 50, the adapter 20, and the first connector 40 connected to the Y1 port, the first controller 22 on the adapter 20 receives the feedback signal from the electrode 10 at the Y1 port through the corresponding communication transmission line 211, and judges whether the handshake is successful. If it fails, it proceeds to step 105; if it succeeds, it proceeds to step 108.

[0141] This judgment step can occur in the adapter 20 or the electric field generator 30. In this embodiment, the judgment step occurs in the adapter 20. Specifically, when the electrode piece 10 at the Y1 port is connected normally, its handshake chip 17 can receive the handshake request signal from the electric field generator 30 and feed back the handshake status to the first controller 22 of the adapter 20. The first controller 22 determines that the handshake is successful. Conversely, when the electrode piece 10 at the Y1 port is connected abnormally, the first controller 22 of the adapter 20 does not receive the feedback signal from its handshake chip 17, and the first controller 22 determines that the handshake has failed.

[0142] In step 108, after the electric field generator 30 sends a handshake signal to the electrode 10 connected to the Y2 port through the second connector 50, the adapter 20, and the first connector 40 connected to the Y2 port, the first controller 22 on the adapter 20 receives the feedback signal from the electrode 10 at the Y2 port through the corresponding communication transmission line 211, and determines whether the handshake is successful. If it fails, proceed to step 105; if it succeeds, proceed to step 109.

[0143] This determination step can occur in the adapter 20 or the electric field generator 30. In this embodiment, the determination step occurs in the adapter 20. Specifically, when the electrode 10 at the Y1 port is connected normally, its handshake chip 17 can receive the handshake request signal from the electric field generator 30 and feed back the handshake status to the first controller 22 of the adapter 20. The first controller 22 determines that the handshake is successful. Conversely, if the electrode plate 10 at the Y2 port is abnormally connected, the first controller 22 of the adapter 20 will not receive the feedback signal from its handshake chip 17, and the first controller 22 will determine that the handshake has failed.

[0144] In the above steps 103, 106, 107, and 108, the adapter 20 receives the handshake signal from the tumor electric field therapy system 100.Subsequently, the first controller 22 needs to control the corresponding grounding switch 25 and bidirectional switching switch 26 to close the grounding switch 25 that is only electrically connected to the handshake chip 17, while all other grounding switches 24 are opened and the sampling terminals 1 and input terminals 2 of the corresponding bidirectional switching switches 26 are all turned on and off. This allows the handshake chip 17 to be electrically connected to the grounding pin GND of the adapter 20 through the first connector 40, so that the handshake chip 17 can work normally. If the electric field generator 30 is properly connected to the adapter 20, between the adapters 20, and between the adapter 20 and the electrode plate 10, then the handshake signal emitted by the electric field generator 30 can eventually reach the handshake chip 17 of the electrode plate 10, and the handshake status of the handshake chip 17 can be fed back to the electric field generator 30. If at least one connection abnormality occurs between the electric field generator 30 and the adapter 20, between the adapters 20 and each other, or between the adapter 20 and the electrode 10, the handshake chip 17 will fail to connect VCC and GND to form a circuit, resulting in the adapter 20 and the electric field generator 30 receiving an empty handshake status signal, thus the handshake will fail.

[0145] In step 109, the electric field generator 30 of the tumor electric field therapy system 100 sets the electric field parameters and then proceeds to step 110. The electric field parameters include the frequency, voltage, current, or power amplitude of the alternating electric signal, etc.

[0146] In step 110, the adapter 20 sends a temperature reading request to the first connector 40 at the Y1 port and the first connector 40 at the Y2 port to collect the temperature detection signals corresponding to the 40 temperature sensors 14 on the electrode 10 at the Y1 port and the electrode 10 at the Y2 port, and then proceeds to step 111.

[0147] In step 111, the tumor electric field therapy system 100 determines the type of the electrode pad 10 at port Y1 and port Y2 by collecting the temperature signals, and then proceeds to step 112.

[0148] Specifically, the determination of the type of the electrode pad 10 at port Y1 and port Y2 is based on the number of temperature detection signals of the electrode pad 10 at port Y1 and port Y2, which determines the number of temperature sensors 14 for each electrode pad 10 at port Y1 and port Y2. This determination process can occur in the adapter 20 or the electric field generator 30. In this embodiment, the electrode pad 10 has 20 temperature sensors 14, thus having a total of 40 effective temperature signals.

[0149] In step 112, the tumor electric field therapy system 100 determines whether the temperature signals collected by the adapter 20 are abnormal. If abnormal, it proceeds to step 114. If all temperature signals are normal, it proceeds to step 113.

[0150] In step 113, the electric field generator 30 applies an alternating current to a pair of electrode plates 10 connected to ports Y1 and Y2.

[0151] In step 114, the tumor electric field therapy system 100 alarms due to abnormal temperature signals from the electrode 10 connected to the Y1 port or the electrode 10 connected to the Y2 port, and then immediately proceeds to step 120.

[0152] In step 115, the adapter 20 sends temperature reading requests to the first connector 40 of the X1 port and the first connector 40 of the X2 port respectively to collect the temperature signals corresponding to all temperature sensors 14 on the electrode 10 at the X1 port and the electrode 10 at the X2 port, and then proceeds to step 116.

[0153] In step 116, the tumor electric field therapy system 100 determines the type of the electrode 10 at the X1 port and the electrode 10 at the X2 port based on the temperature signals and then proceeds to step 117.

[0154] The type of electrode 10 at port X1 and port X2 is determined by the number of temperature sensors 14 connected to the electrode 10 at port X1 and port X2. This determination process can occur in adapter 20 or electric field generator 30. In this embodiment, the electrode 10 has 20 temperature sensors 14, so there are a total of 40 valid temperature signals. Specification 29 / 34 pages 32 CN 120983809 A

[0155] In step 117, the tumor electric field therapy system 100 determines whether the temperature signal collected by adapter 20 is abnormal. If it is abnormal, it proceeds to step 114. If all 40 valid temperature signals are normal, it proceeds to step 118.

[0156] In step 118, the electric field generator 30 applies an alternating electrical signal to a pair of electrode plates 10 connected to ports X1 and X2, and simultaneously stops applying the alternating electrical signal to the pair of electrode plates 10 connected to ports Y1 and Y2, and proceeds to step 119. The total time for steps 113, 115, 116, 117 to 118 is fixed at 1 second.

[0157] In step 119, the tumor electric field therapy system 100 executes subsequent steps based on whether a user has received a command to turn off the electric field. If a command to turn off the electric field is detected, it proceeds to step 120; if no command to turn off the electric field is detected, it proceeds to step 121.

[0158] In step 120, the tumor electric field therapy system 100 turns off the electric field and proceeds to step 101. At this time, the electric field therapy ends and waits for the next command to turn the electric field on.

[0159] In step 121, the tumor electric field therapy system 100 determines whether the electric field parameters need to be adjusted based on the current electric field amplitude and the acquired temperature signal. If the electric field parameters need to be adjusted, the system proceeds to step 109; otherwise, it proceeds to step 109.Steps 110 to 119 are repeated. The total time for steps 118, 119, 121, 110, 111, 112 to 113 is fixed, which is 1 second in this embodiment. Thus, the tumor electric field therapy system 100 can continuously output alternating electric signals with a period of 2 seconds, alternating between applying an alternating electric signal in a first direction between a pair of electrodes 10 connected to ports X1 and X2 and an alternating electric signal in a second direction between another pair of electrode plates 10 connected to ports Y1 and Y2. Meanwhile, the tumor electric field therapy system 100 can reduce the time interval between turning off the alternating electric signal applied to a pair of electrode plates 10 connected to ports X1 and X2 and turning on the alternating electric signal applied to another pair of electrode plates 10 connected to ports Y1 and Y2 to 0s; and reduce the time interval between turning off the alternating electric signal applied to another pair of electrode plates 10 connected to ports Y1 and Y2 and turning on the alternating electric signal applied to a pair of electrode plates 10 connected to ports X1 and X2 to 0s, thereby extending the electric field therapy time while ensuring the accuracy of temperature acquisition.

[0160] This application also provides some temperature detection methods and alternating electric signal application control methods, which are described below using electrode plates 10 as an example.

[0161] This application embodiment provides an electrode temperature detection method, applied to the electrode 10 or tumor electric field therapy system 100 described above, as shown in FIG12, which includes the following steps:

[0162] Step 210: under the condition that the electrode is normally connected by a handshake chip, control each bidirectional switching switch 26 electrically connected to each electrode unit 12 of the electrode 10 to disconnect the AC signal applied to the dielectric element 15 of each electrode unit 12 of the electrode 10, and at the same time connect the DC signal applied to the signal terminal 14-2 of the temperature sensor 14 of each electrode unit 12 of the electrode 10;

[0163] Step 220: turn on the grounding switch 25 corresponding to the grounding terminal 14-1 of the temperature sensor 14 of each row group electrode unit 12 of the electrode 10 in a time sequence to obtain the temperature detection signal of the temperature sensor 14 of each electrode unit 12 of the electrode 10.

[0164] Step 210 specifically involves: controlling the bidirectional switching switch 26 electrically connected to each electrode unit 12 of the electrode sheet 10 to switch from its end connected to the AC signal to its end connected to the DC signal, that is, controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch from its input terminal 2 to its sampling terminal 1; or

[0165] controlling the bidirectional switching switch 26 electrically connected to each electrode unit 12 of the electrode sheet 10 to switch the dielectric element 15 of each electrode unit 12 of the electrode sheet 10 from the on state to the off state, and simultaneously switching the signal terminal 14-2 of the temperature sensor 14 of each electrode unit 12 of the electrode sheet 10 from the off state to the on state.

[0166] The electrode temperature detection method of this application can quickly and accurately obtain the temperature detection signals of all electrode units of the electrode sheet (see page 30 / 34 of the specification, CN 120983809 A). Furthermore, based on the obtained temperature detection signals from all temperature sensors of the electrode sheet, it can determine whether the temperature sensors of the electrode sheet are faulty, abnormal, or whether the electrode sheet is qualified and needs replacement. It can also, when all temperature sensors of the electrode sheet are normal, determine whether each electrode unit of the electrode sheet is overheated based on the obtained temperature detection signals from all temperature sensors of the electrode sheet, and thereby control the AC signal applied to the electrode sheet or each electrode unit of the electrode sheet. It can also identify the electrode sheet type when the temperature detection signals from all temperature sensors of the electrode sheet are normal.

[0167] Referring to FIG13, this application embodiment also provides an AC signal application control method for tumor electric field therapy, which includes the above-mentioned steps 210 and 220, and after step 220, it further includes:

[0168] Step 260: When it is determined that the electrode 10 does not need to be replaced, the AC signal applied to each electrode unit 12 of the electrode 10 is controlled or adjusted according to the temperature detection signal of the temperature sensor 14 of each electrode unit 12 of the electrode 10.

[0169] Step 260 further includes controlling or adjusting the AC signal applied to each electrode unit 12 of the electrode sheet 10:

[0170] Step 261: When the temperature detection signals of each electrode unit 12 of the electrode sheet 10 are not exceeded by a preset temperature threshold, continue to apply AC signals to each electrode unit 12 of the electrode sheet 10; or

[0171] Step 262: When there is a temperature detection signal in all the temperature detection signals of the electrode units 12 of the electrode sheet 10 that exceeds the preset temperature threshold, stop applying AC signals to the electrode units 12 of the electrode sheet 10.

[0172] The step of stopping applying AC signals to the electrode units 12 of the electrode sheet 10 in step 262 includes stopping applying AC signals to all electrode units 12 of the electrode sheet 10, stopping applying AC signals to the electrode units 12 in the electrode sheet 10 whose temperature detection signals exceed the preset temperature threshold, and stopping applying AC signals to all electrode units 12 in the column where the temperature detection signals of the electrode units 12 in the electrode sheet 10 exceed the preset temperature threshold.

[0173] When the application of AC signals to electrode units 12 in electrode sheet 10 where the temperature detection signal exceeds a preset temperature threshold is stopped, AC signals are continued to be applied to electrode units 12 in electrode sheet 10 where the temperature detection signal does not exceed the preset temperature threshold.

[0174] When the application of AC signals to all electrode units 12 in the column where the temperature detection signal exceeds the preset temperature threshold is stopped, the temperature detection signal in electrode sheet 10 does not exceed the preset temperature threshold and is related to the temperature...Electrode units 12 in different columns whose detection signals exceed the preset temperature threshold are then continuously subjected to AC signals.

[0175] The process of continuing to apply an AC signal to the electrode plate 10 in step 261 is as follows:

[0176] Step 263: When the temperature detection signal is much lower than the preset temperature threshold, continue to apply an AC signal to each electrode unit 12 of the electrode plate 10 by increasing the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode plate 10, or continue to apply an AC signal to each electrode unit 12 of the electrode plate 10 by keeping the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode plate 10 unchanged; or

[0177] Step 264: When the temperature detection signal is close to the preset temperature threshold, continue to apply an AC signal to each electrode unit 12 of the electrode plate 10 by keeping the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode plate 10 unchanged, or continue to apply an AC signal to each electrode unit 12 of the electrode plate 10 by decreasing the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode plate 10.

[0178] Referring to FIG14, this application also provides a signal control method for tumor electric field therapy, used for the above-mentioned electrode sheet 10. The method includes:

[0179] Step 310: Combining control of a set of grounding switches 25 and a set of bidirectional switching switches 26 electrically connected to the corresponding electrode sheet 10 to apply AC signals to each electrode unit 12 of the electrode sheet 10 and executing step 320;

[0180] Step 320: Combining control of a set of grounding switches 25 and a set of bidirectional switching switches 26 electrically connected to the electrode sheet 10 to collect temperature detection signals of each electrode unit of the electrode sheet 10 and executing step 330;

[0181] Step 330: Determining the combined control mode of the set of grounding switches 25 and the set of bidirectional switching switches 26 electrically connected to the electrode sheet 10 according to the collected temperature detection signals and executing step 340;

[0182] Step 340: Control the working state of each electrode unit 12 of the electrode sheet 10 according to the determined combination control method of the grounding switch 25 and the bidirectional switching switch 26.

[0183] The working state of each electrode unit 12 of the electrode sheet 10 mentioned in step 340 includes one of the following: stopping the application of AC signal and continuing to collect temperature detection signal, and stopping the collection of temperature detection signal and continuing to apply AC signal. Continuing to apply AC signal includes continuing to apply AC signal by increasing the voltage or current amplitude of the currently applied AC signal, continuing to apply AC signal by keeping the voltage or current amplitude of the currently applied AC signal unchanged, and continuing to apply AC signal by decreasing the voltage or current amplitude of the currently applied AC signal.

[0184] The operating state of each electrode unit 12 of the electrode sheet 10 is determined by the temperature detection signal it collects. Each electrode unit 12 of the electrode sheet 10 is divided into different regions, and each electrode unit 12 in each region can be cyclically switched between applying an AC signal and collecting a temperature detection signal by a combination of a grounding switch 25 and a bidirectional switching switch 26.

[0185] This application embodiment provides another method for detecting the temperature of an electrode sheet in a tumor electric field therapy system. Referring to FIG15, taking electrode sheet 10 as an example, the temperature detection method includes:

[0186] Step 510: Disconnect the input of AC power signal to electrode sheet 10, perform combined control of multiple grounding switches 25 and multiple bidirectional switching switches 26, and obtain the temperature detection signal of the temperature sensor 14 of electrode sheet 10 corresponding to each combination;

[0187] Step 520: Sample and convert the temperature detection signal detected by each temperature sensor 14 in electrode sheet 10 to obtain a digital temperature signal;

[0188] Step 530: Transmit the digital temperature signal to the electric field generator 30 of tumor electric field therapy system 100 so that the electric field generator 30 can determine the temperature at the corresponding electrode unit 12 according to the digital temperature signal.

[0189] In step 510, “combined control of multiple grounding switches 25 and multiple bidirectional switching switches 26” specifically includes:

[0190] Step 511: Place all bidirectional switching switches 26 at sampling end 1 to conduct the electrical connection between the signal terminals 14-2 of each temperature sensor 14 of all electrode units 12 and the corresponding analog-to-digital converter 23;

[0191] Step 512: Sequentially close one of the multiple grounding switches 25 individually to collect the temperature detection signals detected by the temperature sensors 14 of each electrode unit 12 in the corresponding row group.

[0192] In step 512, sequentially closing one of the multiple grounding switches 25 individually allows the detection channel of the analog-to-digital converter 23 to be electrically connected to each temperature sensor 14 in the row group corresponding to the closed grounding switch 25 to be turned on.

[0193] Thus, the temperature detection signals of each temperature sensor 14 in each row group can be obtained sequentially, and then processed by the adapter 20 or the electric field generator 30 to obtain the temperature corresponding to all electrode units 12 on the electrode sheet 10; thereby making the temperature detection of the patient's body surface more comprehensive and accurate.

[0194] For the tumor electric field therapy system 100 of this application embodiment, temperature detection can also be performed on individual electrode units 12 as needed. The specific process of temperature detection for a certain electrode unit 12 of the electrode sheet 10 is as follows: disconnect the input of the AC signal, place the bidirectional switching switch 26 corresponding to the column group where the electrode unit 12 that needs to be measured individually is located at the sampling end 1, and place the remaining bidirectional switching switches 26 at the input end 2; at the same time, place the column group where the electrode unit 12 that needs to be measured individually is located at the sampling end 2;The grounding switch 25 corresponding to group A of 120983809 is turned on and grounded, while all other grounding switches 25 are turned off. This allows the temperature detection signal from the temperature sensor 14 in the electrode unit 12 requiring individual temperature measurement to be sampled to obtain the temperature of that electrode unit 12. For example, if the electrode unit 12 requiring individual temperature measurement is electrode unit 12-1, then the first bidirectional switch 26-1 corresponding to electrode unit 12-1 is placed at sampling terminal 1, and all other bidirectional switches (second bidirectional switch 26-2, second bidirectional switch 26-3, third bidirectional switch 26-3, and fourth bidirectional switch 26-4) are placed at input terminal 2; simultaneously, the first grounding switch 25-1 corresponding to electrode unit 12-1 is closed and grounded, while all other grounding switches (second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4) are turned off. This allows the temperature of electrode unit 12-1 to be detected.

[0195] This application embodiment also provides another method for applying an alternating current signal for tumor electric field therapy, applied to the above-mentioned tumor electric field therapy system, taking the tumor electric field therapy system 100 in FIG1 as an example for description. Referring to FIG16, the alternating current signal application method includes:

[0196] Step 610: Determine the area where the electrode unit 12 in the electrode sheet 10 to which the alternating current signal needs to be applied is located;

[0197] Step 611: Combine and control multiple grounding switches 25 and multiple bidirectional switching switches 26 electrically connected to the electrode sheet 10 to apply the alternating current signal.

[0198] Step 611, “combining control of multiple grounding switches 25 and multiple bidirectional switching switches 26 electrically connected to electrode plate 10”, specifically includes:

[0199] Step 612: Disconnecting all grounding switches 25 electrically connected to electrode plate 10;

[0200] Step 613: Determining the column group where the electrode unit 12 that needs to be applied AC signal is located, based on the area where the electrode unit 12 that needs to be applied AC signal is located;

[0201] Step 614: Determining the bidirectional switching switch 26 electrically connected to the electrode unit 12 in the column group based on the determined column group where the electrode unit 12 that needs to be applied AC signal is located;

[0202] In step 610: Dividing every four adjacent electrode units 12 in electrode plate 10 into a region, with four electrode units 12 in each region corresponding to a column group, connected to a dual-purpose signal line 19 corresponding to the same bidirectional switching switch 26. In other embodiments, the electrode units 12 may be divided in other ways, which will not be described here.

[0203] Step 615: Control the bidirectional switching switch 26 electrically connected to the electrode unit 12 that requires an AC signal to connect the electrode unit 12 to the AC signal line 28 to apply the AC signal; simultaneously control itsThe remaining bidirectional switching switch 26 disconnects the electrical connection between each electrode unit 12 in the area where no AC signal is applied and the AC signal line 28, thereby stopping the application of AC signal.

[0204] In step 615, "connecting the electrode unit that needs to apply AC signal to the AC signal line 28 to apply AC signal and disconnecting the electrical connection between the electrode unit 12 in the area where no AC signal is applied and the AC signal line 28 to stop applying AC signal" is achieved by placing the bidirectional switching switch 26, which is electrically connected to the electrode unit 12 in the column group corresponding to the area in the electrode sheet 10 where AC signal is to be applied, at its input terminal 2, and placing all the bidirectional switching switches 26, which are electrically connected to the electrode unit 12 in the remaining column groups, at the sampling terminal 1.

[0205] When the above methods are applied to electrode plates 10D, 10E, 10F, and 10H in other embodiments, since there are grounding switches 25 and / or bidirectional switching switches 26 in an idle and disconnected state on the adapter 20 that are not electrically connected to the corresponding electrode plates 10D, 10E, 10F, and 10H, the corresponding grounding switches 25 and / or bidirectional switching switches 26 in an idle and disconnected state do not need to be controlled.

[0206] Although the various operations are depicted in the drawings in a specific order, this should not be construed as requiring that these operations must be performed in the specific order shown or in a sequential order, nor should it be construed as requiring that all the operations shown must be performed to obtain the desired result. (Pages 33 / 34, CN 120983809 A)

[0207] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this application, and not to limit them; although this application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein; and these modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this application, and they should all be covered within the scope of the claims and specification of this application. In particular, as long as there is no structural conflict, the various technical features mentioned in the various embodiments can be combined in any way. This application is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims. Instruction manual, page 34 / 34; 37 CN 120983809 A, Figure 1; Instruction manual, Figure 1 / 13 page; 38 CN 120983809 A, Figure 2; Instruction manual, Figure 2 / 13 page; 39 CN 120983809 A, Figure 3; Instruction manual, Figure 3 / 13 page; 40 CN 120983809 A, Figure 4; Instruction manual, Figure 4 / 13 page.41 CN 120983809 A Figure 5, Appendix 5 of the Specification, page 13 42 CN 120983809 A Figure 6, Appendix 6 of the Specification, page 13 43 CN 120983809 A Figure 7, Appendix 7 of the Specification, page 13 44 CN 120983809 A Figure 8, Appendix 8 of the Specification, page 13 45 CN 120983809 A Figure 9, Figure 10, Appendix 9 of the Specification, page 13 46 CN 120983809 A Figure 11, Appendix 10 of the Specification, page 13 47 CN 120983809 A Figure 12, Figure 13, Appendix 11 of the Specification, page 13 48 CN 120983809 A Figure 14, Figure 15, Appendix 12 of the Specification, page 13 49 CN 120983809 A Figure 16, Appendix 13 of the Specification, page 13 50 CN 120983809 A Abstract Abdominal ultrasound examination method, system and device Abstract The present invention provides a tumor electric field therapy system. The tumor electric field treatment system consists of an electrode array and an electric field generator or an adapter electrically connected with the electrode array. plurality of rows andcolumns on a circuit, the grounding ends of the temperature sensors in the same row are short-circuited through the same grounding wire on the flexible circuit board, and the signal ends of the temperature sensors in the same column are short-circuited through the same dual-purpose signal wire on the flexible circuit board, and the dual-purpose signal wires transmit an alternating current signal to the dielectric elements in a first mode and transmit a direct current signal to each temperature sensor in a second mode. The grounding wires are in a disconnected state in the first mode and are sequentially and independently connected in the second mode. The adapter or the electric field generator transmits the alternating current signal or the direct current signal to the electrode array through the dual-purpose signal wires.

Claims

1. A tumor electric field therapy system, characterized in that, include: An electrode sheet is provided with a flexible circuit board, a plurality of electrode units disposed on the flexible circuit board, and a handshake chip. Each electrode unit includes a dielectric element and a temperature sensor with a signal terminal and a ground terminal. The plurality of electrode units are divided into multiple row groups and multiple column groups in the circuit. The flexible circuit board is provided with multiple ground lines and multiple dual-purpose signal lines. The ground terminals of the temperature sensors located in the same row group are shorted through the same ground line. The ground terminals of the temperature sensors located in different row groups are connected in parallel through different ground lines. The signal terminals of the temperature sensors located in the same column group are shorted through the same dual-purpose signal line. The signal terminals of the temperature sensors located in different column groups are connected in parallel through different dual-purpose signal lines. The electrode sheet has a first mode for applying an AC signal and a second mode for acquiring temperature. Each dual-purpose signal line transmits an AC signal to each dielectric element in the first mode and transmits a DC signal to the signal terminal of each temperature sensor and transmits the temperature signal detected by each temperature sensor in the second mode. Each ground line is in an open state in the first mode and is sequentially and individually turned on in the second mode. and An electric field generator or adapter is electrically connected to the electrode sheet. The adapter or the electric field generator provides an AC signal to each dielectric element of the electrode sheet or a DC signal to the signal terminal of each temperature sensor through each of the dual-purpose signal lines. The adapter or the electric field generator performs handshake communication with the handshake chip of the electrode sheet.

2. The tumor electric field therapy system according to claim 1, characterized in that, The adapter or the electric field generator has a preset temperature threshold, and the adapter or the electric field generator is configured to control or adjust the AC signal applied to each dielectric element of the electrode sheet according to the comparison result between the temperature signal of each temperature sensor of the electrode sheet and the preset temperature threshold.

3. The tumor electric field therapy system according to claim 2, characterized in that, The adapter or the electric field generator is configured to: when the temperature signal is much lower than a preset temperature threshold, continue to apply an AC signal to each dielectric element of the electrode sheet by increasing the voltage or current amplitude of the AC signal currently applied to each dielectric element of the electrode sheet, or continue to apply an AC signal to each dielectric element of the electrode sheet by keeping the voltage or current amplitude of the AC signal currently applied to each dielectric element of the electrode sheet unchanged.

4. The tumor electric field therapy system according to claim 2, characterized in that, The adapter or the electric field generator is configured to: when the temperature signal approaches a preset temperature threshold, continue to apply an AC signal to each dielectric element of the electrode sheet in a manner that maintains the voltage or current amplitude of the AC signal currently applied to each dielectric element of the electrode sheet unchanged, or continue to apply an AC signal to each dielectric element of the electrode sheet in a manner that reduces the voltage or current amplitude of the AC signal currently applied to each dielectric element of the electrode sheet.

5. The tumor electric field therapy system according to claim 2, characterized in that, The adapter or the electric field generator is configured to: when any temperature signal in the temperature signals of the temperature sensors of the electrode sheet exceeds a preset temperature threshold, stop transmitting AC signals to all the dielectric elements of the electrode sheet, or stop applying AC signals to all the dielectric elements in the column group where the dielectric element exceeding the preset temperature threshold is located, and continue applying AC signals to the dielectric elements in the remaining column groups where the temperature signals do not exceed the preset temperature threshold.

6. The tumor electric field therapy system according to claim 1, characterized in that, The adapter or the electric field generator is provided with a switching unit, which includes multiple grounding switches that control the conduction or disconnection of each of the grounding wires of the electrode plate, and multiple bidirectional switching switches that control the transmission of AC signals or DC signals by each of the dual-purpose signal lines of the electrode plate.

7. The tumor electric field therapy system according to claim 6, characterized in that, The adapter is equipped with an AC signal line for transmitting AC signals, a DC power supply, and an analog-to-digital converter with multiple detection channels. The bidirectional switching switch has an input terminal and a sampling terminal. The input terminal is electrically connected to the AC signal line, and the sampling terminal is electrically connected to the DC power supply and a corresponding detection channel. In the first mode, all or part of the bidirectional switching switches are turned on at their input terminals, and all the grounding switches are turned off. In the second mode, all the bidirectional switching switches are turned on at their sampling terminals, and each grounding switch is turned on individually in sequence.

8. The tumor electric field therapy system according to claim 7, characterized in that, The electric field generator or the adapter combination configures the states of each of the grounding switches and each of the bidirectional switching switches.

9. The tumor electric field therapy system according to claim 7, characterized in that, The analog-to-digital converter receives the temperature signals detected by each of the temperature sensors and converts them into multiple digital signals. The adapter determines the type of the electrode plate based on the multiple digital signals.

10. The tumor electric field therapy system according to claim 7, characterized in that, The adapter determines whether the electrode plate has an abnormal temperature based on multiple digital signals.

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