Electrode plate and tumor electric field therapy system

Abstract

The invention provides an electrode plate and a tumor electric field treatment system, the electrode plate is provided with a flexible circuit board, a plurality of electrode units and a handshake chip, and each electrode unit comprises a dielectric element and a temperature sensor with a signal end and a grounding end. The plurality of electrode units are arranged on the flexible circuit board in a space structure in a multi-row and multi-column spaced mode so as to form at least one trunk and a plurality of branches which laterally extend from the trunk and are provided with free tail ends. The plurality of electrode units are arranged in multiple rows and multiple columns on the circuit, the grounding ends in the same row group are connected to the same path of grounding wire on the flexible circuit board, and the dielectric elements and the signal ends in the same column group are connected to the same path of dual-purpose signal wire on the flexible circuit board. Each dual-purpose signal line transmits an alternating current signal to each dielectric element in a first mode and transmits a temperature signal detected by each temperature sensor in a second mode, and each grounding line is disconnected in the first mode and is sequentially and independently connected in the second mode.

Description

(19) State Intellectual Property Office (12) Invention Patent Application (10) Application Publication Number (43) Application Publication Date (21) Application Number 202511460903.2 (22) Application Date 2024.10.25 (66) Domestic Priority Data 202311809226.1 2023.12.26 CN PCT / CN2023 / 142515 2023.12.27 CN (62) Divisional Application Data 202411499210.X 2024.10.25 (71) Applicant Jiangsu Hailai Xinchuang Medical Technology Co., Ltd. Address 214100, Jiangsu Province, Wuxi City, Huishan Economic Development Zone, Huishan Avenue, No. 1699, Building 7, 7th Floor, Area A and Area B District Applicant Hangzhou Hailai New Creation Medical Technology Co., Ltd. (72) Inventors Ying Jianjun, Yu Jing, Shen Qichao, Hui Jiajie, Zhang Jun Request to keep name not disclosed Hu Tao (51) Int.Cl. A61N 1 / 04 (2006.01) A61N 1 / 36 (2006.01) G01K 13 / 00 (2021.01) (54) Invention Title Electrode Sheet and Tumor Electric Field Therapy System (57) Abstract This application provides an electrode sheet and a tumor electric field therapy system. The electrode sheet is provided with a flexible circuit board, several electrode units and a handshake chip. The electrode unit includes a dielectric element and a temperature sensor with a signal terminal and a ground terminal. Several electrode units are arranged in multiple rows and columns on the flexible circuit board in a spatial structure to form at least one main trunk and several branches extending laterally from the main trunk and having free ends. Several electrode units are arranged in multiple rows and columns on the circuit. The grounding terminals in the same row group are all connected to the same grounding line on the flexible circuit board. The dielectric elements and signal terminals in the same column group are all connected to the same dual-purpose signal line on the flexible circuit board. Each dual-purpose signal line transmits AC signals to each dielectric element in the first mode and transmits temperature signals detected by each temperature sensor in the second mode. Each grounding line is disconnected in the first mode and is individually turned on in the second mode. Claims (2 pages), Description (33 pages), Drawings (13 pages), CN 120983797 A, 2025.11.21, CN 1 20 98 37 97 A. 1. An electrode sheet, applied in a tumor electric field therapy system, characterized in that the electrode sheet comprises a flexible circuit board, a plurality of electrode units disposed on the flexible circuit board, and a handshake chip; each electrode unit includes a dielectric element and a temperature sensor having a signal terminal and a ground terminal, the dielectric element being short-circuited to the signal terminal of the temperature sensor; the plurality of electrode units are spatially arranged in multiple rows and columns on the flexible circuit board to form at least one main trunk and a plurality of branches extending laterally from the main trunk and having free ends; the flexible circuit board is provided with connections for each of the electrode units.The circuit includes multiple grounding lines and multiple dual-purpose signal lines. The electrode units are arranged in multiple rows and columns. The grounding terminals of each temperature sensor in the same row are connected to the same grounding line, while the grounding terminals of each temperature sensor in different rows are connected in parallel via different grounding lines. The signal terminals of each temperature sensor in the same column are connected to the same dual-purpose signal line, while the signal terminals of each temperature sensor in different columns are connected in parallel via different dual-purpose signal lines. The electrode has a first mode for applying an AC signal and a second mode for temperature acquisition. Each dual-purpose signal line transmits an AC signal to each dielectric element in the first mode and transmits the temperature signal detected by each temperature sensor in the second mode. Each grounding line is disconnected in the first mode and sequentially and individually turned on in the second mode. The handshake chip is configured to determine the connection status of the electrode through handshake communication. 2. The electrode sheet according to claim 1, characterized in that the plurality of electrode units comprises twenty electrode units arranged in a spatial structure of four rows and six columns, wherein the main stem comprises electrode units located in the third and fourth columns and a connecting portion longitudinally connecting adjacent electrode units located in the third and fourth columns. 3. The electrode sheet according to claim 2, characterized in that, from a spatial structural perspective, adjacent electrode units located in the third and fourth columns of each row are disconnected. 4. The electrode sheet according to claim 3, characterized in that the electrode sheet is provided with a wiring portion, the wiring portion being erected between the main stems. 5. The electrode sheet according to claim 1, characterized in that the plurality of electrode units comprises twenty electrode units arranged in a spatial structure of four rows and six columns, wherein the main stem comprises electrode units located in the third and fifth columns and a connecting portion longitudinally connecting adjacent electrode units located in the third and fourth columns. 6. The electrode sheet according to claim 5, characterized in that the electrode sheet is provided with a wiring portion, the wiring portion being erected between two electrode units located in the third and fourth columns of one row. 7. The electrode sheet according to claim 2 or 5, characterized in that the twenty electrode units are arranged in four rows and five columns in the circuit, and the flexible circuit board is provided with four grounding lines and five dual-purpose signal lines. 8. The electrode sheet according to claim 1, characterized in that the flexible circuit board is provided with a grounding trace and a communication line, the handshake chip has a grounding pin electrically connected to the grounding trace and a communication pin electrically connected to the communication line, and the grounding pin is connected to one of the multiple grounding lines through the grounding trace. 9. A tumor electric field therapy system, characterized in that it includes at least one pair of electrode sheets according to any one of claims 1 to 8 and an electric field generator for providing alternating current signals to the electrode sheets.10. The tumor electric field therapy system according to claim 9, characterized in that the electric field generator is provided with a set of analog-to-digital converters with multiple detection channels, multiple grounding switches and multiple bidirectional switching switches corresponding to the electrode sheet; each grounding wire of the electrode sheet is grounded through a corresponding grounding switch; each dual-purpose signal line of the electrode sheet is electrically connected to a corresponding bidirectional switching switch; the bidirectional switching switch has an input terminal for receiving AC signals and a sampling terminal electrically connected to a corresponding detection channel; in a first mode, each bidirectional switching switch is turned on at its input terminal and each grounding switch is turned off; in a second mode, each bidirectional switching switch is turned on at its sampling terminal, and each grounding switch is turned on individually in sequence. Claims 2 / 2 Page 3 CN 120983797 A Electrode Patch and Tumor Electric Field Therapy System

[0001] This application is a divisional application filed by the applicant on October 25, 2024, with application number CN202411499210.X and invention title "Electrode Patch, Tumor Electric Field Therapy System and Temperature Detection and Signal Control Method". Technical Field

[0002] This application relates to Tumor Treating Fields (TTF) technology, and more particularly to an electrode patch and a tumor electric field therapy system. Background Art

[0003] Tumor electric field therapy is a method of treating tumors by using a low-intensity, medium-to-high frequency alternating electric field to prevent the formation of spindle microtubules during the mitosis of certain tumor cells, inhibit the separation of intracellular organelles during cell division, and induce apoptosis during mitosis.

[0004] Compared with traditional cancer treatment methods, TTF has an innovative mechanism of action. Some physiological characteristics of tumor cells, such as their geometry and high-frequency mitosis, make them susceptible to the effects of TTF. TTF disrupts the normal aggregation of tubulin by applying directional forces to polar particles (such as macromolecules and organelles) within the cell. These processes may lead to physical damage to the cell membrane and apoptosis. During the telophase of mitosis, the morphology of the cleavage groove leads to uneven electric field distribution around it. Simultaneously, under the influence of TTF, the electric field strength at the cleavage groove is significantly enhanced, causing charged substances in the cell to move towards the cleavage groove, interfering with or even destroying cell structure formation, ultimately leading to cell division failure and apoptosis.

[0005] In existing tumor electric field therapy systems, an electric field generator transmits an alternating current signal for tumor electric field therapy to an electrode pad, which then applies an alternating electric field to the patient's tumor site for tumor electric field therapy. When the tumor treatment electric field is applied to the patient's body, heat accumulates at the application site, and the temperature rises accordingly. Therefore, monitoring of the application site is necessary.The temperature is too high, and when the temperature is too high, the electric field strength needs to be adjusted in time to avoid the risk of burns to the patient's skin.

[0006] The tumor electric field therapy system includes at least one pair of electrode pads, and each electrode pad contains multiple electrode units. Even if the same AC signal is applied to each electrode unit, the heat generated on each electrode unit will be different due to its different location. That is, the temperature of each electrode unit on the entire electrode pad will not be completely consistent. This may result in some electrode units in the entire electrode pad having a temperature exceeding the preset temperature, while the temperature of other electrode units is normal. In order to ensure that the tumor electric field therapy has a sufficiently long application time while avoiding low-temperature burns to the patient's skin, it is necessary to individually control the overheated electrode units. However, for existing electrode pads, individual control of electrode units requires setting a conductive trace for each electrode unit in the substrate of the electrode pad. This will increase the number of conductive traces in the substrate of the electrode pad, making the electrode pad difficult to bend, and the cable electrically connected to the electrode pad will also be thickened, making the overall weight of the electrode pad heavier, which is not conducive to the application of the electrode pad.

[0007] Therefore, it is necessary to provide an improved electrode pad and tumor electric field therapy system.

[0008] The purpose of this application is to provide an electrode sheet with a handshake chip and a tumor electric field therapy system.

[0009] To achieve the above objective, this application provides the following technical solution: an electrode sheet applied to a tumor electric field therapy system, the electrode sheet having a flexible circuit board, a plurality of electrode units disposed on the flexible circuit board, and a handshake chip, as described in the specification 1 / 33 page 4 CN 120983797 A The electrode unit includes a dielectric element and a temperature sensor with a signal terminal and a ground terminal. The dielectric element is short-circuited to the signal terminal of the temperature sensor. A plurality of electrode units are arranged in multiple rows and columns on the flexible circuit board to form at least one main trunk and several branches extending laterally from the main trunk with free ends. The flexible circuit board has multiple ground lines and multiple dual-purpose signal lines connecting each electrode unit. The electrode units are also arranged in multiple rows and columns in the circuit. The ground terminals of each temperature sensor in the same row are connected to the same ground line, while the ground terminals of each temperature sensor in different rows are connected in parallel through different ground lines. The signal terminals of each temperature sensor in the same column are connected to the same dual-purpose signal line, while the signal terminals of each temperature sensor in different columns are connected in parallel through different dual-purpose signal lines. The electrode sheet has a first mode for applying an AC signal and a second mode for temperature acquisition. Each dual-purpose signal line transmits an AC signal to each dielectric element in the first mode and transmits the signal detected by each temperature sensor in the second mode.Temperature signal, each of the grounding wires is disconnected in the first mode and sequentially turned on individually in the second mode; the handshake chip is configured to determine the connection status of the electrode sheet through handshake communication.

[0010] Further, a plurality of the electrode units include twenty electrode units arranged in a four-row, six-column spatial structure, wherein the main trunk includes electrode units located in the third and fourth columns respectively and a connecting portion longitudinally connecting adjacent electrode units located in the third and fourth columns.

[0011] Further, adjacent electrode units located in the third and fourth columns of each row are disconnected.

[0012] Further, the electrode sheet is provided with a wiring portion, and the wiring portion is mounted between the main trunks.

[0013] Further, a plurality of the electrode units include twenty electrode units arranged in a four-row, six-column spatial structure, wherein the main trunk includes electrode units located in the third and fifth columns and a connecting portion longitudinally connecting adjacent electrode units located in the third and fourth columns.

[0014] Further, the electrode sheet is provided with a wiring portion, which is mounted between two electrode units located in the third and fourth columns of one row.

[0015] Further, the twenty electrode units are arranged in four rows and five columns in the circuit, and the flexible circuit board is provided with four grounding lines and five dual-purpose signal lines.

[0016] Further, the flexible circuit board is provided with a grounding trace and a communication line, and the handshake chip has a grounding pin electrically connected to the grounding trace and a communication pin electrically connected to the communication line. The grounding pin is connected to one of the multiple grounding lines through the grounding trace.

[0017] This application also provides the following technical solution: a tumor electric field therapy system, including the aforementioned electrode sheet and an electric field generator that provides an AC signal to the electrode sheet.

[0018] Further, the electric field generator is provided with a set of analog-to-digital converters with multiple detection channels, multiple grounding switches, and multiple bidirectional switching switches corresponding to the electrode sheet. Each grounding wire of the electrode sheet is grounded through a corresponding grounding switch, and each dual-purpose signal line of the electrode sheet is electrically connected to a corresponding bidirectional switching switch. The bidirectional switching switch has an input terminal for receiving AC signals and a sampling terminal electrically connected to a corresponding detection channel. In the first mode, each bidirectional switching switch is turned on at its input terminal, and each grounding switch is turned off. In the second mode, each bidirectional switching switch is turned on at its sampling terminal, and each grounding switch is turned on individually in sequence.

[0019] The above description is only an overview of the technical solution of this application. In order to better understand the technical means of this application and to implement it according to the contents of the specification, and to make the above and other objects, features, and advantages of this application more apparent and understandable, specific embodiments of this application are described below. Specification2 / 33 Page 5 CN 120983797 A Brief Description of the Drawings

[0020] Figure 1 is a schematic diagram of a tumor electric field therapy system according to an embodiment of this application, showing a spatial structure diagram of the electrode sheet of the first embodiment;

[0021] Figure 2 is a schematic diagram of the structural layout of a modified embodiment of the electrode sheet of the tumor electric field therapy system shown in Figure 1 of this application;

[0022] Figure 3 is a schematic diagram of the circuit connection of the tumor electric field system shown in Figure 1 of this application, showing a circuit connection diagram of the electrode sheet of the first embodiment shown in Figure 1 or the electrode sheet of the modified embodiment shown in Figure 2 with the adapter shown in the first embodiment of Figure 1;

[0023] Figure 4 is a schematic block diagram of the internal structure of the adapter shown in Figure 3 of this application;

[0024] Figure 5 is a schematic block diagram of the internal structure of the electric field generator of the tumor electric field therapy system shown in Figure 1 of this application;

[0025] Figure 6 is similar to Figure 3, and is a schematic diagram of the circuit connection of a tumor electric field therapy system according to a second embodiment of this application, showing a circuit connection diagram of the electrode sheet of the second embodiment of the tumor electric field therapy system shown in Figure 3 with the adapter shown in Figure 3.

[0026] Figure 7, similar to Figure 3, is a circuit connection diagram of the tumor electric field therapy system according to the third embodiment of this application, showing the circuit connection diagram between the electrode sheet of the third embodiment of the tumor electric field therapy system and the adapter shown in Figure 3;

[0027] Figure 8, similar to Figure 3, is a circuit connection diagram of the tumor electric field therapy system according to the fourth embodiment of this application, showing the circuit connection diagram between the electrode sheet of the fourth embodiment of the tumor electric field therapy system and the adapter shown in Figure 3;

[0028] Figure 9, similar to Figure 3, is a circuit connection diagram of the tumor electric field therapy system according to the fifth embodiment of this application, showing the circuit connection diagram between the electrode sheet of the fifth embodiment of the tumor electric field therapy system and the adapter shown in Figure 3;

[0029] Figure 10 is a flowchart of a temperature detection method for the tumor electric field therapy system according to this application;

[0030] Figure 11 is a flowchart of the tumor electric field therapy system according to this application;

[0031] Figure 12 is another flowchart of a temperature detection method for the tumor electric field therapy system according to this application;

[0032] Figure 13 is a flowchart illustrating the AC signal application control method for tumor electric field therapy according to this application;

[0033] Figure 14 is a flowchart illustrating the signal control method for tumor electric field therapy according to this application;

[0034] Figure 15 is a flowchart illustrating the electrode temperature detection method according to this application;

[0035] Figure 16 is a flowchart illustrating the AC signal application method for tumor electric field therapy according to this application.

[0036] Explanation of reference numerals:

[0037] Tumor electric field therapy system 100, electrode sheets 10, 10', 10D, 10E, 10F, 10H, flexible circuit boards 11, 11D, 11E, 11F, 11H, connecting parts 111, 111', wiring parts 112, 112', bridging parts 113, 113', main trunk 114, 114', branch 115, 115', first interval D1, D1', second interval D2, D2', electrode unit 12, 12', first cable 13, 13', temperature sensor 14, grounding terminal 14-1, signal terminal 14-2, dielectric element 15, diode 16, handshake chip 17, grounding trace 171, communication line 172, grounding wire 18, first grounding wire 18- 1. Second grounding wire 18-2, Third grounding wire 18-3, Fourth grounding wire 18-4, Dual-purpose signal line 19, First dual-purpose signal line 19-1, Second dual-purpose signal line 19-2, Third dual-purpose signal line 19-3, Fourth dual-purpose signal line 19-4, Fifth dual-purpose signal line 19-5, Adapter 20, Second cable 21, First controller 22, Analog-to-digital converter 23, Voltage divider resistor 24, Grounding switch 25, First grounding switch 25-1, Second grounding switch 25-2, Third grounding switch 25-3, Fourth grounding wire 18-4, Instruction manual 3 / 33 Page 6 CN 120983797 A Ground switch 25-4, bidirectional switch 26, first bidirectional switch 26-1, second bidirectional switch 26-2, third bidirectional switch 26-3, fourth bidirectional switch 26-4, fifth bidirectional switch 26-5, first communication unit 27, AC signal line 28, first power module 29, communication transmission line 211, electric field generator 30, second power module 31, second controller 32, second communication unit 33, AC signal generator 34, AC signal switch 35, first AC signal switch 35-1, first AC signal switch 35-2, first AC signal switch 35-3, first AC signal switch 35-4, first connector 40, 40D, 40E, 40F, 40H, first plug 41, 41', first socket 42, second connector 50, second plug 51, second socket 52. Detailed Description

[0038] The embodiments of the technical solution of this application will be described in detail below with reference to the accompanying drawings. The following embodiments are only used to more clearly illustrate the technical solutions of this application, and are therefore only examples, and cannot be used to limit the scope of protection of this application.

[0039] FIG1 is a schematic diagram of a tumor electric field therapy system 100 according to an embodiment of this application. As shown in FIG1, the tumor electric field therapy system 100 includes: at least a pair of electrode plates 10, an adapter 20 connected to the electrode plates 10, and an electric field generator 30 connected to the adapter 20. The electric field generator 30 generates an alternating current signal for tumor treatment and applies it to the electrode plates 10 through the adapter 20.An alternating current signal is applied to generate a therapeutic electric field between the paired electrode pads 10. An adapter 20 is electrically connected between the electrode pads 10 and the electric field generator 30 to transmit the alternating current signal generated by the electric field generator 30 to the electrode pads 10. In other words, the electric field generator 30 generates an alternating current signal, which is transmitted to each electrode pad 10 through the adapter 20, generating a therapeutic electric field for treating tumors between the same pair of electrode pads 10. As shown in Figure 1, in this embodiment, there are four electrode pads 10. From a spatial arrangement perspective, each electrode pad 10 includes multiple electrode units 12 arranged in both axially and centrally symmetrical configurations, several connecting portions 111 located between adjacent electrode units 12, bridging portions 113 spanning between adjacent connecting portions 111, wiring portions 112 connected to the bridging portions 113, and a first cable 13 connected to the wiring portions 112. The bridging portion 113 and the wiring portion 112 are arranged perpendicularly to each other, forming a "T" shape. The bridging portion 113 is installed between two adjacent connecting portions 111. Each electrode unit 12 of the electrode plate 10 is electrically connected to the adapter 20 through a first cable 13 with 10 core wires.

[0040] Each electrode unit 12 has a temperature sensor 14 and a dielectric element 15. The temperature sensor 14 is used to detect the temperature of the part of the electrode unit 12 that is applied to the patient's body surface. It can be a thermistor element or a temperature sensor other than a thermistor, and can be set at any position on the electrode unit 12. The dielectric element 15 is used to apply an alternating current signal to the tumor site of the patient. The dielectric element 15 can be a dielectric ceramic sheet or a polymer dielectric layer made of polymer material. In this embodiment, each dielectric element 15 has a through hole (not labeled) in the middle to accommodate a corresponding temperature sensor 14. Each electrode unit 12 may also include a diode 16 connected in series with the temperature sensor 14, which can prevent reverse current flow to prevent detection signals from other electrode units 12 from affecting the temperature sensor 14. The ground terminal 14-1 of the temperature sensor 14 is connected in series with the anode of the diode 16 and grounded through the cathode of the diode 16.

[0041] In the first mode, the electrode unit 12 applies an alternating current signal through the dielectric element 15; in the second mode, the temperature of the patient's body surface to which the corresponding electrode unit 12 is applied is detected or acquired by the temperature sensor 14; in the third mode, the application of the alternating current signal is stopped and temperature detection and acquisition are stopped. The first mode, the second mode, and the third mode do not overlap in time. That is, the time period during which the dielectric element 15 of the electrode unit 12 applies an alternating current signal is staggered and does not overlap with the time period during which the temperature sensor 14 detects the temperature. The electrode unit 12 can apply an alternating current signal through its dielectric element 15 and through its temperature sensor 14.The sensor 14 cycles through temperature detection, meaning the electrode unit 12 can cycle through the first mode and the second mode. (Page 4 / 33, CN 120983797 A) The electrode unit 12 can also cycle through the first mode, the second mode, and the third mode, meaning the electrode unit 12 cycles through applying an AC signal through the dielectric element 15, acquiring or detecting temperature through the temperature sensor 14, stopping the application of the AC signal, and acquiring temperature.

[0042] Each electrode sheet 10 includes an electrode array (unnumbered) consisting of 20 electrode units 12. The electrode array (unlabelled) also includes a flexible circuit board 11 comprising a connection portion 111, a wiring portion 112, and a bridging portion 113. Twenty electrode units 12 are spaced apart in the electrode array (unlabelled) arranged in four rows and six columns. Specifically, the first and last rows each have four electrode units 12, and the middle two rows each have six electrode units 12. The four electrode units 12 in the first row are located in the second to fifth columns, the six electrode units 12 in each of the middle two rows are located in the first to sixth columns, and the four electrode units 12 in the last row are also located in the second to fifth columns. The connection portion 111 is located only between adjacent electrode units 12 arranged in the column direction in the third and fourth columns, and between adjacent electrode units 12 in the row direction, except for the two electrode units 12 located in the third and fourth columns of each row. That is, the two adjacent electrode units 12 in the third and fourth columns are connected only in the column direction by the connecting part 111, and are disconnected in the row direction without being connected by the connecting part 111; the electrode units 12 in the first, second, fifth and sixth columns are connected only by the horizontally arranged connecting part 111 and the electrode unit 12 adjacent to them in the row direction, and are disconnected in the column direction and with the adjacent electrode units 12. In other words, the two adjacent electrode units 12 in the column direction in the first, second, fifth and sixth columns are disconnected.

[0043] The electrode unit 12 in the third column and the connecting part 111 between the electrode units 12 in that column and arranged vertically, and the electrode unit 12 in the fourth column and the connecting part 111 between the electrode units 12 in that column and also arranged vertically, all constitute the backbone 114 of the electrode array (unlabeled). The connecting portions 111 located on opposite sides of the electrode units 12 in the third and fourth columns, and connected to the electrode units 12 in the third and fourth columns respectively via laterally arranged connecting portions 111, and the electrode units 12 connected to the laterally arranged connecting portions 111, all constitute branches 115 of the electrode array (unlabeled). That is, in this embodiment, the electrode array (unlabeled) includes two main trunks 114 and several branches extending laterally from the two main trunks 114.Branches 115. Each branch 115 has a free end away from the main trunk 114. The free ends of adjacent branches 115 are disconnected, and the position and distance between adjacent branches 115 can be freely adjusted according to the actual usage scenario. Specifically, one main trunk 114 is composed of each electrode unit 12 located in the third column and a connecting part 111 located between adjacent electrode units 12 in that column and arranged longitudinally. Another main trunk 114 is composed of each electrode unit 12 located in the fourth column and a connecting part 111 located between adjacent electrode units 12 in that column and arranged longitudinally. The remaining electrode units 12 connected to the main trunk 114 by the transversely arranged connecting parts 111 and the transversely arranged connecting parts 111 are all branches 115.

[0044] Specifically, the branches 115 are as follows: a connecting portion 111 extending laterally to the left from the electrode unit 12 in the first row of the third column and located in the first row, and an electrode unit 12 connected to the connecting portion 111 and located in the second column of the first row; two connecting portions 111 extending laterally to the left from the electrode unit 12 in the second row of the third column and located in the second row, and two electrode units 12 located in the first and second columns of the second row; two connecting portions 111 extending laterally to the left from the electrode unit 12 in the third row and located in the third row, and two electrode units 12 located in the first and second columns of the third row; and two connecting portions 111 extending laterally to the left from the electrode unit 12 in the fourth row of the third column and located in the fourth row. A connecting portion 111 in the fourth row and an electrode unit 12 in the second column of the fourth row; a connecting portion 111 extending laterally to the right from the electrode unit 12 in the first row of the fourth column and an electrode unit 12 in the fifth column of the first row; two connecting portions 111 extending laterally to the right from the electrode unit 12 in the second row of the fourth column and two electrode units 12 in the fifth and sixth columns of the second row; two connecting portions 111 extending laterally to the right from the electrode unit 12 in the third row of the fourth column and two electrode units 12 in the fifth and sixth columns of the third row; a connecting portion 111 extending laterally to the right from the electrode unit 12 in the fourth row of the fourth column and an electrode unit 12 in the fifth column of the fourth row.

[0045] The electrode array (unlabeled) is divided into a symmetrical left portion comprising three columns on the left and a right portion comprising three columns on the right, with the left and right portions connected only by a bridging portion 113. The left portion consists of a main stem 114 located in the third column and several branches 115 extending laterally to the left from the main stem 114, and the right portion consists of a main stem 114 located in the fourth column and several branches 115 extending laterally to the right from the main stem 115. The two main stems 114 are connected by a bridge erected between them.The connection is made at the joint 113. Specifically, the two main trunks 114 are electrically connected by a bridging portion 113 between the connecting portions 111 of the electrode units 12 in the second row of the third column and the connecting portions 111 of the electrode units 12 in the second row of the fourth column and the connecting portions 111 of the electrode units 12 in the third row of the fourth column. The connecting portions 111 of the electrode units 12 in the second row of the third column and the connecting portions 111 of the electrode units 12 in the second row of the third column and the connecting portions 111 of the electrode units 12 in the second row of the fourth column and the connecting portions 113 are generally arranged in an "H" shape. In other embodiments, the bridging portion 113 may also be provided between an electrode unit 112 located in the third column and an electrode unit 12 located in the fourth column. Optionally, the bridging portion 113 is provided between two electrode units 12 located in the third and fourth columns and adjacent in the row direction.

[0046] Each electrode unit 12, according to its position in the electrode array (unlabeled), can be divided into peripheral electrode units 12 and central electrode units 12. The peripheral electrode units 12 include four electrode units 12 in the first row, two electrode units 12 at opposite ends of the second row, two electrode units 12 at opposite ends of the third row, and four electrode units 12 in the fourth row. The central electrode units 12 include four electrode units 12 in the middle of the second row and four electrode units 12 in the middle of the third row. Among the multiple peripheral electrode units 12, some adjacent electrode units 12 are connected by a horizontally arranged connecting part 111, while some adjacent electrode units 12 are disconnected. Among the multiple peripheral electrode units 12, the adjacent electrode units 12 connected by the connecting part 111 are some row-adjacent electrode units 12. Specifically, among the multiple electrode units 12 located on the periphery, the two electrode units 12 that are adjacent in the column direction or diagonally adjacent are all disconnected; some of the two electrode units 12 that are adjacent in the row direction are also disconnected; only some of the two electrode units 12 that are adjacent in the row direction are connected by a laterally extending connecting portion 111. Among the multiple electrode units 12 located in the center, only the two electrode units 12 that are adjacent in the column direction on the main trunk 114 are connected by a longitudinally arranged connecting portion 111, and only the two electrode units 12 that are adjacent in the row direction on the branch 115 are connected by a laterally arranged connecting portion 111.

[0047] The electrode array (unlabeled) also has intervals (unlabeled) formed between a number of spaced electrode units 12, which allows moisture from the patient's skin to escape, allows the patient's skin to exchange heat with the outside world, or allows the patient's skin to breathe freely, and also allows the positions and spacing between the branches 115 to be freely adjusted, and also avoids wrinkles when the electrode pads 10 are applied. The intervals (unnumbered) include the first interval D1 located between the two main trunks 114 and the second interval D2 located between the branches 115.The first interval D1 is located between the third column electrode unit 12 and the fourth column electrode unit 12, and the second interval D2 is located between the electrode units 12 in adjacent rows. That is, along the row upwards, the electrode unit 12 in the third column and the adjacent electrode unit 12 in the fourth column are disconnected and no connecting part 111 is provided, but the aforementioned first interval D1 is formed; and along the column upwards, only the two adjacent electrode units 12 in the third and fourth columns are connected by the connecting part 111, while the two adjacent electrode units 12 in the other four columns are not connected by the connecting part 111, but the aforementioned second interval D2 is formed. The setting of the first and second intervals D1 and D2 can also increase the degree of freedom of some electrode units 12 and can also avoid wrinkles when attaching the electrode sheet 10.

[0048] The electrode sheet 10 also includes a handshake chip 17 disposed on the flexible circuit board 11 and used to confirm its connection status. The handshake chip 17 can communicate with the electric field generator 30 through the adapter 20 to determine the connection status between the electrode sheet 10 and the adapter 20. The electric field generator 30 of the tumor electric field therapy system 100 first sends a handshake communication signal to the handshake chip 17 of the electrode 10 through the adapter 20, and determines the connection status of the electrode 10 based on whether it receives feedback from the handshake chip 17. After confirming that the electrode 10 is connected normally through the handshake chip 17, the electric field generator 30 of the tumor electric field therapy system 100 applies an AC signal to the dielectric element 15 of the electrode 10 or transmits a DC signal to each temperature sensor 14 of the electrode 10 to collect temperature detection signals. The handshake chip 17 can be an EEPROM with encryption function.

[0049] In some other embodiments, the tumor electric field therapy system 100 may have more or fewer electrode 10s. In some other embodiments, each pair of electrode 10 has the same or different number of electrode units 12, and different pairs of electrode 10 may also have different numbers of electrode units 12. In some other embodiments, 20 electrode units 12 may also be arranged in other ways. Of course, in some other embodiments, the electrode sheet 10 may also have other numbers of electrode units 12. In some other embodiments, the 20 electrode units 12 may also be arranged in other ways, as shown in the electrode sheet 10' in FIG2. Of course, in some other embodiments, the electrode sheet 10 may also have other numbers of electrode units 12. In short, the implementation of this application is not limited by the number and arrangement of the electrode units 12 of the electrode sheet 10.

[0050] The electrode sheet 10' shown in FIG2 is a modified embodiment of the electrode sheet 10 shown in FIG1. ​​The spatial structure of the electrode sheet 10' is the same as that of the electrode sheet 10, and it also includes a plurality of electrode units 12' arranged at intervals and a plurality of electrodes located between adjacent electrodes.The connection portion 111' between units 12', the wiring portion 112' connected to the bridging portion 113', and the first cable 13' connected to the wiring portion 112', the first interval D1 formed between the third column electrode units 12' and the fourth column electrode units 12', and the second interval D2' formed between the electrode units 12' in adjacent rows; the connection portion 111', the wiring portion 112', and the bridging portion 113' also constitute a flexible circuit board (not labeled), and the electrode sheet 10' is also plugged into the adapter 20 through the first plug 41' of the first cable 13' with 10 core wires, the only difference being that: the two adjacent electrode units 12' in the fourth column are both disconnected. The electrodes are not connected by vertically arranged connecting portions 111', but adjacent electrode units 12' in the fifth column are connected by vertically arranged connecting portions 111'. Each electrode unit 12' in the fourth column is connected to the adjacent electrode unit 12' in the fifth column by horizontally arranged connecting portions 111'. A bridging portion 113' connects the two electrode units 12' located in the third row and third column and the two electrode units 12' located in the third row and fourth column. One main branch 114' is composed of the electrode unit 12' located in the third column and the connecting portion 111' between the electrode units 12' in that column, and another main branch 114' is composed of the electrode unit 12' located in the fifth column and the connecting portion 111' between the electrode units 12' in that column. The structure of the left side of the left three columns of the electrode array (unlabeled) is exactly the same as the structure of the left side of the electrode array (unlabeled) shown in Figure 1. Only the right side is different because the position of the main stem 114' changes from the fourth column to the fifth column, resulting in the branches 115' in the right side extending to the left and right sides of the corresponding electrode units 12' in the main stem 114'.

[0051] Figure 3 is a schematic diagram of the circuit connection between the electrode sheet 10 of the first embodiment of the tumor electric field therapy system 100 shown in Figure 1 or the electrode sheet 10' of the variant embodiment shown in Figure 2 and the adapter 20 of the first embodiment. It is worth noting that the arrangement of the electrode units 12 shown in Figure 3 is to more clearly show the electrical connection between an electrode sheet 10 and the adapter 20. The arrangement of the electrode units 12 shown in Figure 3 does not represent the spatial arrangement of the electrode units 12. The circuit connection is described below using the electrode sheet 10 in the first embodiment as an example.

[0052] Referring to Figures 1 and 3, in this embodiment, each electrode sheet 10 is provided with 20 electrode units 12. The 20 electrode units 12 are arranged in the order of 1 to 20 in the circuit connection, and are divided into four row groups and five column groups, that is, the 20 electrode units 12 are arranged in four rows and five columns in the circuit connection. The temperature sensor 14 of each electrode unit 12 includes a ground terminal 14-1 and a signal terminal 14-2. The dielectric element 15 and the temperature sensor 14 of each electrode unit 12 are soldered to the flexible circuit.On board 11, the dielectric element 15 is shorted to the signal terminal 14-2 of the corresponding temperature sensor 14. Since the electrode units 12 are arranged in a four-row, five-column configuration in the circuit connection, and each electrode unit includes a corresponding dielectric element 15 and a corresponding temperature sensor 14, the multiple temperature sensors 14 are also arranged in a four-row, five-column configuration in the circuit connection, and the multiple dielectric elements 15 are also arranged in a four-row, five-column configuration in the circuit connection. It should be noted that this arrangement is for clearer illustration of the electrical connection between the electrode sheet 10 and the adapter 20, and does not represent the spatial arrangement of the electrode units 12. The spatial structure described in the specification (page 7 / 33, CN 120983797 A) may be a roughly array-like structure as shown in Figure 1, or other structures, such as petal-shaped or scattering shapes, and can be regular or irregular. The dielectric element 15 is configured to apply an alternating electric field to the patient's tumor site. Temperature sensor 14 is configured to detect the temperature of the patient's body surface in contact with electrode pad 10 and output a temperature detection signal to adapter 20.

[0053] Flexible circuit board 11 is embedded with multiple conductive traces 171, 172, 18, and 19, which include multiple ground lines 18, multiple dual-purpose signal lines 19, one ground trace 171, and one communication line 172. One end of ground trace 171 is connected to the ground pin of handshake chip 17, and the other end is connected to any one of the ground lines 18. The ground pin of handshake chip 17 is connected to ground trace 171, and its communication pin is electrically connected to communication line 172. That is, handshake chip 17 is grounded through ground line 18 connected to ground trace 171 and communicates with external devices through communication line 172. Specifically, the handshake chip 17 is grounded via a ground trace 171 connected to its ground pin and a ground line 18. It then sequentially connects to the communication line 172 of the flexible circuit board 11, a wire electrically connected to the first cable 13 and the communication line 172, an adapter 20 electrically connected to the first cable 13, and an electric field generator 30 electrically connected to the adapter 20, thereby determining the connection status of the electrode plate 10. The first cable 13 has multi-core wires (not shown) electrically connected to the communication line 172, the multiple ground lines 18, and the multiple dual-purpose signal lines 19 of the flexible circuit board 11, respectively. The total number of communication lines 172, ground lines 18, and dual-purpose signal lines 19 embedded in the flexible circuit board 11 does not exceed 10. Therefore, the number of wires in the first cable 13 does not exceed 11.

[0054] The number of conductive lines electrically connected to the grounding wire 18 in the tumor electric field therapy system 100 is related to the number of rows M of the electrode unit 12, and can be greater than or equal to the number of rows M of the electrode unit 12, where M is a positive integer. Tumor electric field therapy system 100The number of conductive lines electrically connected to the dual-purpose signal lines 19 is related to the number of columns N of the electrode units 12, which can be greater than or equal to the number of columns N of the electrode units 12, where N is a positive integer. In this embodiment, the number of grounding lines 18 is equal to the number of rows M of the electrode units 12; the number of columns N of the electrode units 12 is equal to the number of columns N of the electrode units 12. The number of lines L embedded in the flexible circuit board 11 is equal to the sum of the number of grounding lines 18 and the number of dual-purpose signal lines 19 plus 2, that is, L=M+N+2. The number of conductors in the first cable 13 is M+N+1.

[0055] The multiple dual-purpose signal lines 19 of the flexible circuit board 11 are respectively arranged in a one-to-one correspondence with the multiple columns of the electrode units 12, and are configured to transmit the AC signal generated by the electric field generator 30 to the dielectric element 15 in each electrode unit 12 in the corresponding column. That is, the dielectric elements 15 located in the same column group are all short-circuited through the same dual-purpose signal line 19 of the flexible circuit board 11, and the dielectric elements 15 located in different column groups are connected in parallel through different dual-purpose signal lines 19 of the flexible circuit board 11. The dual-purpose signal lines 19 of the flexible circuit board 11 are electrically connected to the corresponding wires in the first cable 13, and then electrically connected to the electric field generator 30 through the adapter 20. That is, the dual-purpose signal lines 19 of the flexible circuit board 11 receive the AC signal generated by the electric field generator 30 through the first cable 13 and the adapter 20.

[0056] The multiple grounding lines 18 are respectively set to correspond one-to-one with the multiple rows of the electrode unit 12, and the multiple grounding lines 18 are respectively used to short-circuit and ground the temperature sensor 14 of each corresponding electrode unit 12 in each row group. That is, the grounding terminals 14-1 of multiple temperature sensors 14 located in the same row group are all short-circuited through the same grounding line 18 of the flexible circuit board 11, and the grounding terminals 14-1 of temperature sensors 14 located in different row groups are connected in parallel through different grounding lines 18 of the flexible circuit board 11. During the temperature detection period or in the second mode, only one of the multiple grounding lines 18 is conducting at any given time, and the rest are disconnected.

[0057] Each of the multiple dual-purpose signal lines 19 is also configured to transmit DC signals to the temperature sensor 14 in each electrode unit 12 in the corresponding column group to collect and transmit the detected temperature detection signal. Multiple temperature sensors 14 located in different column groups have their respective signal terminals 14-2 connected in parallel via different dual-purpose signal lines 19 on the flexible circuit board 11. Multiple temperature sensors 14 located in the same column group have their respective signal terminals 14-2 shorted to the same dual-purpose signal line 19 on page 8 / 33 of the flexible circuit board specification (CN 120983797 A 11), and the shorting point serves as a temperature sampling point. Specifically, each dual-purpose signal line 19 is configured to short-connect the signal terminal 14-2 of at most one temperature sensor 14 of each row group to a signal line for receiving signals.The external device for measuring signals includes multiple dual-purpose signal lines 19, each connected to a different signal terminal 14-2 of the temperature sensor 14 to avoid repetitive signal outputs from the dual-purpose signal lines 19. Specifically, when the number of electrode units 12 in a row group is the same as the number of dual-purpose signal lines 19, each dual-purpose signal line 19 is electrically connected to the signal terminal 14-2 of a different electrode unit 12 in that row group; when the number of electrode units 12 in a row group is less than the number of dual-purpose signal lines 19, at least one dual-purpose signal line 19 is not electrically connected to the signal terminal 14-2 of the temperature sensor 14 of the electrode unit 12, and the remaining dual-purpose signal lines 19 are electrically connected to the signal terminal 14-2 of a different electrode unit 12 in that row group. In this embodiment, the external device for receiving the detection signal is an adapter 20. The dual-purpose signal line 19 of the flexible circuit board 11 receives DC signals from the adapter 20 or the electric field generator 30 through the first cable 13, and transmits the collected or detected temperature signals to the adapter 20, and then to the electric field generator 30 through the adapter 20.

[0058] In this embodiment, with each electrode unit 12 equipped with a temperature sensor 14 for temperature detection, the above-mentioned circuit design reduces the number of wires in the first cable 13, avoiding the cable from becoming thicker and harder, thus increasing the difficulty of cable fixation; at the same time, it avoids the increased number of wires in the first cable 13 affecting the adhesion effect between the electrode sheet 10 and the corresponding body surface of the patient's tumor site.

[0059] The flexible circuit board 11 has a total of 9 lines, including the grounding wire 18 and the dual-purpose signal line 19. In this embodiment, the flexible circuit board 11 has 4 lines for the grounding wire 18 and 5 lines for the dual-purpose signal line 19. Specifically, the electrode sheet 10 in this embodiment includes four grounding wires 18, each grounding wire 18 being used to ground the grounding terminals 14-1 of the temperature sensors 14 in the same row group. The four grounding wires 18 of the electrode sheet 10 are respectively the first grounding wire 18-1, the second grounding wire 18-2, the third grounding wire 18-3, and the fourth grounding wire 18-4. In the four rows of the electrode sheet 10, the first row group includes electrode units 12-1 to 12-5, the second row group includes electrode units 12-6 to 12-10, the third row group includes electrode units 12-11 to 12-15, and the fourth row group includes electrode units 12-16 to 12-20. Specifically, the first grounding wire 18-1 is used to ground electrode units 12-1 to 12-5 in the first row group; the second grounding wire 18-2 is used to ground electrode units 12-6 to 12-10 in the second row group; and the third grounding wire 18-3 is used to ground electrode units 12-11 to 12-5 in the third row group.Electrode units 12-15 are grounded; the fourth grounding line 18-4 is used to ground electrode units 12-16 to 12-20 in the fourth row group. It should be noted that these grounding lines 18 can be selectively closed or opened, which can be achieved by connecting each grounding line 18 in series with a switch, as will be described in detail below. The phrase "grounding electrode unit 12" can refer to grounding the ground terminal 14-1 of the temperature sensor 14 in electrode unit 12, or it can refer to the diode 16 being connected in series with the temperature sensor 14 of the same electrode unit 12 and grounded together. In short, each grounding line 18 short-circuits and grounds the ground terminals 14-1 of the temperature sensors 14 in all electrode units 12 in the corresponding row group. The fourth grounding line 18-4 is also short-circuited with the grounding trace 171 connected to the ground pin of the handshake chip 17.

[0060] Continuing to refer to FIG3, the electrode sheet 10 of this embodiment further includes five dual-purpose signal lines 19. One end of each dual-purpose signal line 19 is connected to all electrode units 12 in each row group, and the other end is connected to an adapter 20 for receiving temperature detection signals and transmitting AC signals. That is, for each row group, each dual-purpose signal line 19 can be selectively connected to one of the electrode units 12 or not connected to any of the electrode units 12 in that row group to avoid the dual-purpose signal line 19 outputting repeated signals in the future. Specifically, the five dual-purpose signal lines 19 of the electrode sheet 10 include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the four electrode units 12 (electrode units 12-1, 12-6, 12-11, and 12-16) and the signal terminal 14 of their respective temperature sensors 14. (Instruction manual, page 9 / 33, CN 120983797 A 2); one end of the second dual-purpose signal line 19-2 is simultaneously connected to electrode units 12-2, 12-7, and 12-... 12. The dielectric element 15 of each of the four electrode units 12 (12-17) and the signal terminal 14-2 of each of their respective temperature sensors 14 are connected simultaneously to the dielectric element 15 of each of the four electrode units 12 (12-3, 12-8, 12-13, and 12-18) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is connected simultaneously to the dielectric element 15 of each of the four electrode units 12 (12-4, 12-9, 12-14, and 12-19) and the signal terminal 14-2 of each of their respective temperature sensors 14.Terminal 14-2; one end of the fifth dual-purpose signal line 19-5 is connected to the dielectric element 15 of each of the four electrode units 12 (electrode units 12-5, 12-10, 12-15, and 12-20) and the signal terminal 14-2 of the temperature sensor 14. In short, each dual-purpose signal line 19 short-circuits the dielectric element 15 of each electrode unit 12 and the signal terminal 14-2 of each temperature sensor 14 in the same column group for connection to external devices. It should be noted that these dual-purpose signal lines 19 can selectively transmit AC signals or receive temperature detection signals. This can be achieved by connecting each dual-purpose signal line 19 in series with a bidirectional switch 26 and coordinating the closing or opening of the grounding wire 18, which will be described in detail below.

[0061] In other embodiments, the number of grounding wires 18 and dual-purpose signal lines 19 embedded in the flexible circuit board 11 may vary depending on the circuit arrangement and number of electrode units 12 in different electrode sheets, which will be specifically described in subsequent embodiments.

[0062] In this embodiment, the grounding pin of the handshake chip 17 used to confirm the connection status of the electrode sheet 10 is connected to the fourth grounding wire 18-4 through the grounding trace 171 embedded in the flexible circuit board 11. The first cable 13 has 10 core wires, namely 4 grounding wires 18, 5 dual-purpose signal lines 19 and 1 communication line 172. The specific connection relationship and working principle of the handshake chip 17 will be described in detail below.

[0063] The tumor electric field therapy system 100 of this embodiment includes at least one pair of the above-mentioned electrode sheets 10, an adapter 20 electrically connected to the electrode sheets 10 and an electric field generator 30 electrically connected to the adapter 20. The adapter 20 is connected between the electrode sheet 10 and the electric field generator 30. When the grounding pin of the handshake chip 17 is grounded under the control of the electric field generator 30 or the adapter 20, the electric field generator 30 sends a handshake communication signal to the handshake chip 17 of the electrode plate 10 via the communication line 172 of the adapter 20 and the electrode plate 10 to determine the connection status of the electrode plate 10. When the electrode plate 10 is properly connected, the electric field generator 30 provides AC signals to the dielectric elements 15 in the multiple electrode units 12 of the electrode plate 10 via the dual-purpose signal line 19 of the adapter 20 and the electrode plate 10, or provides DC signals to the temperature sensors 14 in the multiple electrode units 12 of the electrode plate 10 via the dual-purpose signal line 19 of the adapter 20 and the electrode plate 10, and is used to receive temperature detection signals output by the temperature sensors 14 in the multiple electrode units 12. The adapter 20 is configured to send a handshake communication signal to the communication line 172 of the electrode plate 10 according to the communication command of the electric field generator 30, and is configured to transmit the AC signal generated by the electric field generator 30 to the dual-purpose signal line of the electrode plate 10.Line 19 is configured to transmit DC signals to the dual-purpose signal line 19 of the electrode sheet and receive temperature detection signals output from the multiple dual-purpose signal line 19 of the electrode sheet 10.

[0064] Continuing to refer to Figures 3 and 4, the adapter 20 includes: a first controller 22, a multiple communication transmission line 211 electrically connected to the first controller 22, multiple sets of analog-to-digital converters 23 connected to the first controller 22, multiple sets of voltage-reducing resistors 24 and multiple sets of grounding switches 25 corresponding to the multiple sets of analog-to-digital converters 23, multiple sets of bidirectional switching switches 26 corresponding to the multiple sets of analog-to-digital converters 23, a first communication unit 27, AC signal lines 28 corresponding to each set of bidirectional switching switches 26, and a first power module 29 simultaneously connected to the first communication unit 27, the first controller 22, and the multiple sets of analog-to-digital converters 23. The first power module 29 provides DC power VCC to each electronic component of the adapter 20. The adapter 20 also includes multiple circuit lines (unlabeled). Among them, the multiple circuit lines (unnumbered) are electrically connected one-to-one with the multiple grounding lines 18, multiple dual-purpose signal lines 19, and communication lines 172 in the flexible circuit board 11 of the corresponding electrode plate 10 through the first cable 13 of the corresponding electrode plate 10. (Page 10 / 33 of the instruction manual CN 120983797 A 10) The multiple circuit lines (unlabeled) include multiple AC signal lines 28 that transmit AC signals to the corresponding electrode 10 and are electrically connected to the multi-purpose signal lines 19 in the flexible circuit board 11 of the corresponding electrode 10; multiple circuit lines (unlabeled) that are electrically connected one-to-one to the multi-purpose signal lines 19 in the flexible circuit board 11 of the corresponding electrode 10 and are used to power the temperature sensors 14 of the electrode 10 or transmit the temperature detection signals of the electrode 10; multiple circuit lines (unlabeled) that are electrically connected one-to-one to the grounding lines 18 in the flexible circuit board 11 of the corresponding electrode 10; and multiple communication transmission lines 211 that are electrically connected one-to-one to the communication lines 172 in the flexible circuit board 11 of the corresponding electrode 10. All communication transmission lines 211 are connected to the first controller 22. Each communication transmission line 211 is connected to the communication line 172 of the flexible circuit board 11 through the corresponding first connector 40, and the first controller 22 and the handshake chip 17 are electrically connected to the handshake chip 17 through the grounding switch 25 corresponding to the grounding line 18 shorted by the grounding pin of the handshake chip 17 of the closed flexible circuit board 11, so that the handshake chip 17 can obtain power and enable the data communication function.

[0065] The number P of the circuit lines P that the adapter 20 is electrically connected to one electrode piece 10 is equal to the sum of the number of rows M and the number of columns N of the electrode unit 12 of the electrode piece 10 plus 2; the number H of the circuits H that the adapter 20 is electrically connected to X electrode pieces 10 is equal to X times the number of circuit lines that it is electrically connected to a single electrode piece 10, that is. The number of groups of grounding switches 25, the bidirectional switching switchThe number of groups of switches 26, the number of AC lines 28, and the number of communication transmission lines 211 are all related to the number of electrode pieces 10. The number of groups of grounding switches 25, the number of groups of bidirectional switching switches 26, the number of AC lines 28, and the number of communication transmission lines 211 are all the same; and not less than the number of electrode pieces 10. Preferably, the number of groups of grounding switches 25, bidirectional switching switches 26, AC lines 28, and communication transmission lines 211 are all the same as the number of electrode pieces 10. The following is a detailed description of the electrical connection between an electrode piece 10 with 20 electrode units 12 and the adapter 20.

[0066] Each group of grounding switches 25 is provided with multiple grounding switches 25. The multiple grounding switches 25 are respectively connected to the adapter 20 and electrically connected to the circuit lines (unlabeled) that correspond one-to-one with the multiple grounding lines 18 of a corresponding electrode piece 10, and are configured to control the conduction or disconnection of the multiple grounding lines 18. The circuit lines (unlabeled) of the multiple grounding wires 18, each electrically connected to an electrode sheet 10, are grounded at the end near the grounding switch 25. The number of grounding switches 25 in each group is related to the number of grounding wires 18 on the flexible circuit board 11 of the corresponding electrode sheet 10; in this embodiment, the two are equal. As shown in Figure 3, in this embodiment, each group of grounding switches 25 includes a first grounding switch 25-1, a second grounding switch 25-2, a third grounding switch 25-3, and a fourth grounding switch 25-4. Each group of multiple grounding switches 25 controls the closing or opening of the corresponding grounding wire 18 of a corresponding electrode sheet 10. Specifically, the first grounding switch 25-1 is used to control the closing or opening of the first grounding wire 18-1 of the corresponding electrode sheet 10, and can then cooperate with the corresponding group of bidirectional switching switches 26 to control the energization and de-energization of the temperature sensors 14 of the five electrode units 12 from electrode unit 12-1 to electrode unit 12-5 in the first row of the electrode sheet 10. The second grounding switch 25-2 is used to control the opening or closing of the second grounding wire 18-2 of the electrode plate 10, and can cooperate with the corresponding set of bidirectional switching switches 26 to control the power supply and de-energization of each temperature sensor 14 of the five electrode units 12 (electrode units 12-6 to 12-10) in the second row of the electrode plate 10; the third grounding switch 25-3 is used to control the opening or closing of the third grounding wire 18-3 of the electrode plate 10, and can cooperate with the corresponding set of bidirectional switching switches 26 to control the power supply and de-energization of each temperature sensor 14 of the five electrode units 12 (electrode units 12-11 to 12-15) in the third row of the electrode plate 10; the fourth grounding switch 25-4 is used to control the opening or closing of the fourth grounding wire 18-4 of the electrode plate 10, and can determine the connection status of the electrode plate 10 by the electrical connection status of the communication line 172 of the handshake chip 17 and the communication transmission line 211 of the adapter 20, and also...It can cooperate with the corresponding bidirectional switching switch 26 to control the power supply and de-energization of each temperature sensor 14 of the five electrode units 12 from electrode unit 12-16 to electrode unit 12-20 in the fourth row group of the electrode pad 10. The above-mentioned grounding switch 25 can be a mechanical switch, such as a relay. The grounding switch 25 can also be an electronic switch, and each grounding switch 25 can be opened and closed by the first controller 22 of the adapter 20.

[0067] In this embodiment, all the grounding switches 25 are electronic switches. The first controller 22 is communicatively connected to the multiple grounding switches 25 and is used to sequentially and cyclically control the opening and closing states of multiple grounding switches 25 in each group of grounding switches 25, thereby sequentially and individually energizing each grounding wire 18 in the multiple grounding wires 18 of the corresponding electrode pad 10 and cooperating with the switching of the corresponding bidirectional switching switch 26, so as to sequentially and time-divisionally collect the temperature of the patient's body surface detected by all temperature sensors 14 on the electrode pad 10. The number of grounding switches 25 in each group is greater than or equal to the number of grounding wires 18 on the flexible circuit board 11 of the corresponding electrode 10. In this embodiment, the number of grounding switches 25 in each group is the same as the number of grounding wires 18 on the corresponding electrode 10.

[0068] Each group of bidirectional switching switches 26 is provided with multiple bidirectional switching switches 26. The multiple bidirectional switching switches 26 in each group are respectively connected to the adapter 20 and electrically connected to the circuit lines (unlabeled) that correspond one-to-one with the multi-channel dual-purpose signal lines 19 of the corresponding electrode 10. The number of bidirectional switching switches 26 in each group of bidirectional switching switches 26 is related to the number of dual-purpose signal lines 19 on the flexible circuit board 11 of the corresponding electrode 10, which is greater than or equal to the number of dual-purpose signal lines 19 on the flexible circuit board 11 of the corresponding electrode 10. In the embodiment shown in FIG3, the two are equal. Each bidirectional switch 26 has a sampling terminal 1 and an input terminal 2. The sampling terminals 1 of multiple bidirectional switches 26 in the same group are electrically connected to the corresponding detection channels of multiple detection channels of a corresponding group of analog-to-digital converters 23, and each detection channel corresponds to a corresponding temperature sampling point. The input terminal 2 of each bidirectional switch 26 in the same group is electrically connected to the corresponding AC signal line 28. Each bidirectional switch 26 is configured to control the multiplexer signal line 19 to connect to the corresponding AC signal line 28 to transmit AC signals or to connect to the corresponding detection channel of the corresponding group of analog-to-digital converters 23 to receive the temperature detection signal output by the temperature sensor 14.

[0069] As shown in FIG3, taking the electrical connection of an electrode plate 10 with the adapter 20 as an example, in this embodiment with 20 electrode units 12, the multiple bidirectional switches 26 are respectively the first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4, the fifth bidirectional switch 26-5, the sixth bidirectional switch 26-6, the sixth bidirectional switch 26-7, the sixth bidirectional switch 26-8, the sixth bidirectional switch 26-9, the sixth bidirectional switch 26-1, the sixth bidirectional switch 26-2, the sixth bidirectional switch 26-3, the sixth bidirectional switch 26-4, the sixth bidirectional switch 26-5, the sixth bidirectional switch 26-6, the sixth bidirectional switch 26-7, the sixth bidirectional switch 26-8, the sixth bidirectional switch 26-9, the sixth bidirectional switch 26-1 ...Three bidirectional switching switches 26-3, 26-4, and 26-5. Multiple bidirectional switching switches 26 in the same group control the switching of a corresponding dual-purpose signal line 19 of the same electrode plate 10 between transmitting AC signals and transmitting temperature detection signals.

[0070] Specifically, the first bidirectional switching switch 26-1 controls the switching of the first dual-purpose signal line 19-1 of the corresponding electrode plate 10 between transmitting AC signals and transmitting temperature detection signals, thereby controlling the conduction of each dielectric element 15 of the electrode units 12-1, 12-6, 12-11, and 12-16 in the first column of the electrode plate 10, and the conduction of each temperature sensor 14 of the electrode units 12-1, 12-6, 12-11, and 12-16 in the first column of the electrode plate 10. The switching between the conduction of signal terminal 14-2 and the corresponding grounding switches 25-1, 25-2, 25-3, and 25-4 is coordinated to enable the first column of electrode units 12-1, 12-6, 12-11, and 12-16 to transmit AC signals to the patient or output temperature detection signals collected by the temperature sensors 14 of the electrode units 12 to the corresponding analog-to-digital converter 23; the second bidirectional switching switch 26-2 is used to control the switching between transmitting AC signals and transmitting temperature detection signals of the second dual-purpose signal line 19-2 of the corresponding electrode pad 10, thereby controlling the conduction of each dielectric element 15 of the electrode units 12-2, 12-7, 12-12, and 12-17 in the second column of the electrode pad 10 and the conduction of the electrode units 12-2, 12-7, 12-12, and 12-17 in the second column of the electrode pad 10. The switching between the conduction of the signal terminals 14-2 of each temperature sensor 14 and the corresponding grounding switches 25-1, 25-2, 25-3, and 25-4 is coordinated to enable the second row of electrode units 12-2, 12-7, 12-12, and 12-17 to transmit AC signals to the patient or output temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23; the third bidirectional switch 26-3 is used to control the switching between transmitting AC signals and transmitting temperature detection signals on the third dual-purpose signal line 19-3 of the corresponding electrode pad 10. (Instruction manual, page 12 / 33, CN 120983797 A) This controls the conduction of each dielectric element 15 in the third column group of electrode units 12-3, 12-8, 12-13, and 12-18 of the electrode sheet 10, and the conduction of each dielectric element 15 in the third column group of electrode units 12-3, 12-8, and 12-18.The switching between the conduction of the signal terminals 14-2 of the temperature sensors 14 of electrode units 12-13 and 12-18 and the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4, enables the third row of electrode units 12-3, 12-8, 12-13, and 12-18 to transmit AC signals to the patient or output temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23; the fourth bidirectional switching switch 26-4 is used to control the corresponding electrode pads 10. The fourth dual-purpose signal line 19-4 switches between transmitting AC signals and transmitting temperature detection signals, thereby controlling the switching between the conduction of each dielectric element 15 of electrode units 12-4, 12-9, 12-14, and 12-19 in the fourth column of the electrode sheet 10 and the conduction of the signal terminals 14-2 of each temperature sensor 14 in the fourth column of the electrode unit 12-4, 12-9, 12-14, and 12-19, and corresponding to the first grounding switch 25-1, the second grounding switch 25-2, and the third grounding switch 25-3. The fourth grounding switch 25-4 is used to enable the fourth column of electrode units 12-4, 12-9, 12-14, and 12-19 to transmit AC signals to the patient or output temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23; the fifth bidirectional switching switch 26-5 is used to control the switching of the fifth dual-purpose signal line 19-5 of the corresponding electrode pad 10 between transmitting AC signals and transmitting temperature detection signals, thereby controlling the dielectric elements of each electrode unit 12-5, 12-10, 12-15, and 12-20 in the fifth column of the electrode pad 10. The switching between the conduction of component 15 and the conduction of the signal terminals 14-2 of the temperature sensors 14 of each temperature sensor 14 in the fifth column group of electrode units 12-5, 12-10, 12-15, and 12-20, and cooperating with the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4, enables the fifth column of electrode units 12-5, 12-10, 12-15, and 12-20 to transmit AC signals to the patient or output temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23.

[0071] When each group of grounding switches 25 is open and the input terminal 2 of each group of bidirectional switching switches 26 is on and the sampling terminal 1 is off, AC signals can be transmitted to the dielectric elements 15 of each electrode unit 12 of the corresponding electrode sheet 10.When the sampling terminal 1 of switch 26 is turned on and the input terminal 2 is turned off, it can cooperate with each grounding switch 25 in the corresponding group of grounding switches 25 to transmit the temperature detection signals collected by the temperature sensors 14 of each electrode unit 12 on the electrode plate 10 in a time-division manner. The above-mentioned bidirectional switching switch 26 can be a mechanical switch, such as a relay. The bidirectional switching switch 26 can also be an electronic switch, and the switching between the sampling terminal 1 and the input terminal 2 of each bidirectional switching switch 26 can be controlled by the first controller 22 of the adapter 20.

[0072] In this embodiment, all of the multiple groups of bidirectional switching switches 26 are electronic switches. The first controller 22 is communicatively connected to the multiple groups of bidirectional switching switches 26 and is used to control the multiple bidirectional switching switches 26 in each group of bidirectional switching switches 26 to switch between their respective sampling terminal 1 and input terminal 2, and cooperate with the closing or opening of the corresponding grounding switch 25 to continuously monitor the temperature of the patient's body surface detected by all the temperature sensors 14 on the electrode plate 10 or to transmit AC signals to the patient. In this embodiment, the multiple groups of grounding switches 25 and the multiple groups of bidirectional switching switches 26 together form a switch unit (not labeled).

[0073] In this embodiment, each group of analog-to-digital converters 23 is electrically connected one-to-one to the sampling terminals 1 of multiple bidirectional switching switches 26 in the corresponding group through multiple circuit lines (unlabeled) in the adapter 20, and is configured to receive the temperature detection signal transmitted by the multi-purpose signal line 19 of the corresponding electrode sheet 10, and convert the temperature detection signal from an analog signal to a digital signal. Each group of analog-to-digital converters 23 includes multiple detection channels A, B, C, D, and E, each detection channel A, B, C, D, and E is used to connect to one corresponding dual-purpose signal line 19 in the multi-purpose signal line 19 through the corresponding bidirectional switching switch 26. The number of detection channels in each group of analog-to-digital converters 23 is related to the number of bidirectional switching switches 26 in the corresponding group. The number of detection channels in each group of analog-to-digital converters 23 is related to the number of column groups of electrode units 12 of the corresponding electrode sheet 10. Specifically, the number of detection channels in each group of analog-to-digital converters 23 (page 13 / 33 of the specification, CN 120983797 A) is equal to the number of bidirectional switching switches 26 in the corresponding group of bidirectional switching switches 26, and is not less than the number of column groups of electrode units 12 of the corresponding electrode sheet 10. As shown in Figure 3, each group of analog-to-digital converters 23 contains a total of 5 detection channels A, B, C, D, and E, which are respectively the first detection channel A, the second detection channel B, the third detection channel C, the fourth detection channel D, and the fifth detection channel E. The first detection channel A is connected to the first dual-purpose signal line 19-1 through the sampling terminal 1 of the first bidirectional switching switch 26-1; the second detection channel B is connected to the second dual-purpose signal line 19-2 through the sampling terminal 1 of the second bidirectional switching switch 26-2; and the third detection channel C is connected to the third dual-purpose signal line 19-2 through the sampling terminal 1 of the third bidirectional switching switch 26-3.Using signal line 19-3, the fourth detection channel D is connected to the fourth dual-purpose signal line 19-4 through the sampling terminal 1 of the fourth bidirectional switching switch 26-4, and the fifth detection channel E is connected to the fifth dual-purpose signal line 19-5 through the sampling terminal 1 of the fifth bidirectional switching switch 26-5. Each detection channel A, B, C, D, and E is used to receive the temperature detection signal collected by the temperature sensor 14 of the electrode unit 12 connected to the corresponding dual-purpose signal line 19. In addition, each detection channel A, B, C, D, and E is connected to the first power module 29, which provides the detection voltage to the detection channel A, B, C, D, and E, through a corresponding voltage divider resistor 24 in the adapter 20. The first power module 29 provides DC power signals.

[0074] In this embodiment, the first communication unit 27 is configured to acquire the digital signals output by multiple sets of analog-to-digital converters 23 and send the digital signals to the electric field generator 30. The electric field generator 30 is also configured to control and adjust the voltage, current, or power of the AC signal supplied to the plurality of electrode units 12 of the electrode pad 10 according to the received digital signal. For example, when any of the received digital signals exceeds a preset threshold, it indicates that the temperature detected by at least one temperature sensor 14 in the electrode pad 10 at the corresponding dielectric element 15 applied to the human body surface exceeds the preset threshold temperature (e.g., 41°C, 42°C, etc.). In this case, the voltage, current, or power of the AC signal output by the electric field generator 30 can be appropriately reduced to avoid the electrode units 12 of the electrode pad 10 becoming too hot when the AC signal is applied, causing low-temperature burns to the patient's skin. The aforementioned preset threshold temperature and preset threshold can be determined based on human safety thresholds. The first communication unit 27 is controlled by the first controller 22 and serially transmits digital signals converted by multiple sets of analog-to-digital converters 23. In this embodiment, the preset temperature threshold can be a value within the range of 36°C to 45°C.

[0075] One end of each of the multiple communication transmission lines 211 embedded in the adapter 20 is connected to the first controller 22, and the other end is electrically connected to a communication line 172 that is electrically connected to the communication pin of the handshake chip 17 of the corresponding electrode 10 through the corresponding wire of the corresponding first cable 13. The ground pin GND of the adapter 22 is also connected to the corresponding wire of the corresponding first cable 13 through a wire that is electrically connected to the corresponding ground switch 25, a ground wire 18 that is connected to both the corresponding wire of the first cable 13 and the ground trace 171, and a ground trace 171 that is shorted to the ground wire 18 to achieve the connection with the ground pin of the handshake chip 17 of the corresponding electrode 10. That is, the first controller 22 controls the ground switch 25 corresponding to the ground wire 18-4 that is shorted to the ground pin of the handshake chip 17 of the electrode 10 to close, and sends a handshake communication signal to the communication line 172 of the electrode 17 through the communication transmission line 211, and the first controller 22 can receive the communication line of the electrode 10 according to whether it can receive the communication line of the electrode 10.The feedback provided by 172 is used to determine whether the connection between the electrode 10 and the adapter 20 is normal.

[0076] Referring to Figures 4 and 5, in this embodiment, the first power module 29 is electrically connected to the second power module 31 of the electric field generator 30 and is configured to supply power to the first controller 22, multiple analog-to-digital converters 23, and the first communication unit 27 of the adapter 20. Each electrode 10 is connected to the adapter 20 by a first connector 40, which is adapted to connect the corresponding electrode 10 to the adapter 20. As shown in Figure 1, the first connector 40 includes a first plug 41 located at the end of the first cable 13 away from the electrode 10 and a first socket 42 located on the adapter 20. The first plug 41 and the first socket 42 are press-type spring connectors, that is, the first connector 40 connects the adapter 20 and the electrode 10 by means of a connector. Each first cable 13 has five wires electrically connected to bidirectional switch 26-1, 26-2, 26-3, 26-4, and 26-5 in the corresponding set of bidirectional switch 26; four wires electrically connected to grounding switches 25-1, 25-2, 25-3, and 25-4 in the corresponding set of grounding switches 25; and one wire electrically connected to both the communication line 172 of the electrode plate 10 and the communication transmission line 211 of the adapter 20. That is, each first connector 40 is electrically connected to a corresponding set of bidirectional switch 26, a corresponding set of grounding switches 25, and a corresponding communication transmission line 211 connected to the first controller 22 via ten wires; and is connected to the electric field generator 30 via a corresponding AC signal line 28 of the adapter 20.

[0077] A second connector 50 is provided between the adapter 20 and the electric field generator 30. The second connector 50 is adapted to connect the electric field generator 30 to the adapter 20. The adapter 20 also includes a second cable 21 connected to the second connector 50. The second connector 50 includes a second plug 51 located at the end of the second cable 21 away from the first controller 22 and a second socket 52 located on the electric field generator 30. The second plug 51 and the second socket 52 are push-button spring connectors, that is, the second connector 50 connects the adapter 20 and the electric field generator 30 by means of a connector. Each first connector 40, such as X1, Y1, X2, and Y2, is connected to a second connector 50 via a corresponding AC signal line 28. Each first connector 40, such as X1, Y1, X2, and Y2, is connected to a corresponding set of grounding switches 25, a corresponding set of analog-to-digital converters 23, and a corresponding communication transmission line 211. Each first connector 40 is also connected to the second connector 50 and a corresponding communication transmission line 211 via a corresponding set of bidirectional switching switches 26.The second cable 21 has eight wires, including four wires 1 to 4 that are electrically connected to the corresponding AC signal lines 28 for transmitting AC signals, one wire 5 that is electrically connected to the data receiving line RX of the first communication unit 27, one wire 6 that is electrically connected to the data transmitting line TX of the first communication unit 27, one wire 7 that is electrically connected to the VCC power line of the first power module 29, and one wire 8 that is electrically connected to the GND line of the first power module 29. The second connector 50 is connected to the first communication unit 27 via the data receiving line RX and the data transmitting line TX. The VCC pin of the second connector 50 is connected to the VCC power line of the first power module 29, and the GND pin of the second connector 50 is connected to the GND line of the first power module 29 and grounded. The VCC pin of the second connector 50 is also connected to the corresponding voltage-reducing resistors 24 and the corresponding analog-to-digital converters 23 via the VCC power line of the first power module 29.

[0078] Referring to FIG5, the electric field generator 30 includes: a second power supply module 31, a second controller 32, an AC signal generator 34, a second communication unit 33, and a set of AC signal switches 35. The VCC pin of the second connector 50 is also electrically connected to the VCC power line of the second power supply module 31, and the GND pin of the second connector 50 is grounded through the GND line of the second power supply module 31. The second power supply module 31 is also connected to and supplies power to the second controller 32 and the AC signal generator 34, respectively. The second communication unit 33 is electrically connected to the wire 5 of the second connector 50 through its data receiving line RX and to the wire 6 of the second connector 50 through its data transmitting line TX, thereby realizing information interaction between the electric field generator 30 and the adapter 20. The second controller 32 is also electrically connected to the second communication unit 33, the AC signal generator 34, and a set of AC signal switches 35. The second controller 32 is configured to control the opening and closing of each AC signal switch 35 in the set of AC signal switches 35 and adjust the relevant parameters of the AC signal applied by the AC signal generator 34 according to the relevant digital signals received from the adapter 20 by the second communication unit 33. The relevant parameters of the AC signal include the voltage, current, and power of the AC signal. The AC signal generator 34 is electrically connected to several wires 1, 2, 3, and 4 of the second connector 50 through the set of AC signal switches 35. The set of AC signal switches 35 includes multiple AC signal switches 35, each corresponding to a specific electrode 10. Each AC signal switch 35 is electrically connected to a corresponding wire 1, 2, 3, or 4 of the second connector 50 through an AC signal wiring 36, and is also electrically connected to the corresponding electrode 10 through the corresponding wires 1, 2, 3, and 4 of the second connector 50, to transmit AC signals to each electrode 10.The AC signal generator 34 is electrically connected to the AC signal switches 35 via a set of AC signal wiring 36.

[0079] Specifically, the number of AC signal switches 35 in the electric field generator 30 is related to the number of electrode plates 10. In this embodiment, the number of AC signal switches 35 is equal to the number of electrode plates 10, and both are 4. The AC signal switches 35 include a first AC signal switch 35-1, a second AC signal switch 35-2, a third AC signal switch 35-3, and a fourth AC signal switch 35-4, which are electrically connected to the wires 1 to 4 of the second connector 50 respectively. One end of the first AC signal switch 35-1 is electrically connected to the AC signal generator 34 via the first AC signal wiring 36 (page 15 / 33 of the instruction manual for the electric field generator 30, CN 120983797 A). The other end is electrically connected to the corresponding AC signal transmission wire 1 in the second connector 50 via the first AC signal wiring 36-1, and then electrically connected to the AC signal line 28 at port X1 of the adapter 20 via the wire 1 of the second connector 50. The AC signal line 28 at port X1 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 at port X1 of the adapter 20 is electrically connected to the corresponding electrode plate 10, so as to control whether the AC signal generator 34 transmits AC signal to the electrode plate 10 electrically connected to port X1 of the adapter 20; the second AC signal switch 35-2 One end of the third AC signal switch 35-3 is electrically connected to the AC signal generator 34 via the second AC signal wiring 36 of the electric field generator 30, and the other end is electrically connected to the corresponding AC signal transmission wire 2 in the second connector 50 via the second AC signal wiring 36-2. It is also electrically connected to the AC signal line 28 at port Y1 of the adapter 20 via the wire 2 of the second connector 50, the AC signal line 28 at port Y1 of the adapter 20, the first connector 40 at port Y1 of the adapter 20, and the corresponding electrode 10, thereby controlling whether the AC signal generator 34 supplies AC signals to the electrode 10 electrically connected to port Y1 of the adapter 20. One end of the third AC signal switch 35-3 is electrically connected to the AC signal generator 34 via the third AC signal wiring 36-3 of the electric field generator 30, and the other end is electrically connected to the corresponding AC signal transmission wire 36-2 in the second connector 50 via the AC signal wiring 36-3. The AC signal generator 34 is electrically connected to the AC signal line 28 located at port X2 of the adapter 20 via the wire 3 of the second connector 50. The AC signal line 28 located at port X2 of the adapter 20 is electrically connected to the first connector 40. The first connector 40 located at port X2 of the adapter 20 is electrically connected to the corresponding electrode plate 10 to control whether the AC signal generator 34 is electrically connected to port X2 of the adapter 20.The electrode 10 transmits an AC signal; one end of the fourth AC signal switch 35-4 is electrically connected to the AC signal generator 34 through the fourth AC signal wiring 36-4 of the electric field generator 30, and the other end is electrically connected to the corresponding AC signal transmission wire 4 in the second connector 50 through the fourth AC signal wiring 36-4, and is electrically connected to the AC signal line 28 at port Y2 of the adapter 20 through the wire 4 of the second connector 50, the AC signal line 28 at port Y2 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 at port Y2 of the adapter 20 is electrically connected to the corresponding electrode 10, so as to control whether the AC signal generator 34 transmits an AC signal to the electrode 10 electrically connected to port Y1 of the adapter 20.

[0080] The working principle of the handshake chip 17 is described in detail below. The handshake chip 17 can store electrical energy when the communication line 172 transmits a high level and release energy when the communication line 172 transmits a low level, through an external energy storage element (not shown), so that the handshake chip 17 can obtain sufficient power and operate normally. Optionally, the energy storage element is a capacitor, so the handshake chip 17 only needs an additional communication core wire to operate normally. The handshake chip 17 is suitable for handshake communication with external devices such as electric field generator 30 or adapter 20 to determine the connection status of each pair of electrode plates 10. After the handshake chip 17 completes handshake communication with adapter 20 and / or electric field generator 30, the state of bidirectional switching switch 26 and grounding switch 25 can be combined to enable the electrode plate 10 to apply an AC signal or perform temperature acquisition. When the electrode 10 needs to acquire or measure temperature, all the bidirectional switching switches 26 on the flexible circuit board 11 of the electrode 10 are located at the sampling end 1. The electric field generator 30 or the adapter 20 can sequentially close each grounding switch 25 so that the analog temperature signal of the corresponding temperature sensor 14 in each row group is simultaneously sampled by the corresponding temperature sampling point. The analog temperature signal detected by each sampled temperature sensor 14 can also be converted into a signal that can characterize the type of the electrode 10 if the electrode 10 is qualified, or it can be used to characterize whether the electrode 10 has a temperature abnormality.

[0081] Specifically, when the first controller 22 of the adapter 20 receives the handshake signal sent by the electric field generator 30, it controls the corresponding grounding switch 25 connected to the grounding pin of the handshake chip 17 to close, so that the handshake chip 17 is powered on and the handshake signal is sent to the handshake chip 17. The handshake chip 17 sends a feedback signal. The first controller 22 on the adapter 20 sends the feedback signal from the handshake chip 17 to the second controller 32 of the electric field generator 30 through the second connector 50. The second controller 32 determines whether the corresponding first controller 22 and the handshake chip 17 have completed handshake communication based on the feedback signal from the handshake chip 17. After the handshake communication is completed, it configures each grounding switch 25 and each bidirectional switch in the switching unit (unlabeled) on the adapter 20.The instruction manual, pages 16 / 33, CN 120983797 A, describes the state of switch 26 to transmit AC signals to the dielectric elements of each electrode unit 12 of the electrode plate 10 or to measure temperature through the temperature sensors 14 of each electrode unit 12 of the electrode plate 10. When the electrode plate 10 is in temperature acquisition mode, the electric field generator 30 controls each bidirectional switch 26 of the adapter 20 through its second controller 32 to ensure that each bidirectional switch 26 is in its respective acquisition terminal 1, and sequentially closes each grounding switch 25, so that each detection channel of the corresponding analog-to-digital converter 23 acquires temperature detection signals from each temperature sensor 14 in a row, and performs analog-to-digital conversion on the acquired temperature analog signals to obtain several AD sampling values, which correspond to digital temperature. The first controller 22 can also send several AD sampling values ​​to the electric field generator 30 through the adapter 20, so that the electric field generator 30 can identify the type of the corresponding electrode 10 according to the several AD sampling values ​​when the electrode 10 is qualified, and / or, in the process of transmitting alternating electrical signals to the corresponding electrode 10, determine whether the corresponding electrode 10 has an abnormal temperature according to the several AD sampling values.

[0082] The working principle of the tumor electric field therapy system 100 of this embodiment will be described in detail below with reference to Figures 3 to 5.

[0083] The second controller 32 of the electric field generator 30 controls the grounding switch 25-4 corresponding to the fourth grounding line 18-4 connected to the handshake chip 17 of the electrode 10 to be in a closed state through the first controller 22 of the adapter 20, and sends a handshake signal to the communication line 172 of the electrode 10 through the first control 22, and determines the connection status between the electrode 10 and the adapter 20 according to whether the feedback of the handshake chip 17 can be received. If the electric field generator 30 receives a feedback signal from the electrode plate 10, it indicates that the connection between the electrode plate 10 and the adapter 20 is normal; then an AC signal can be applied to the electrode plate 10 or a temperature detection signal can be acquired through the temperature sensor 14 of the electrode plate 10. If the electric field generator 30 does not receive a feedback signal from the electrode plate 10, it indicates that the connection between the electrode plate 10 and the adapter 20 is abnormal, and the second controller 32 of the electric field generator 30 issues a connection abnormality prompt to remind the operator. After the operator handles the issue, the second controller 32 continues to control the first controller 22 of the adapter 20 to send a handshake communication signal to the handshake chip 17 of the electrode plate 10, repeating the above-mentioned operation of judging the connection status of the electrode plate 10 until the connection between the electrode plate 10 and the adapter 20 is normal.

[0084] When the electrode plate 10 is connected normally and it is necessary to detect the temperature of each electrode unit 12 of a certain electrode plate 10, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls a set of dual electrodes electrically connected to the electrode plate 10.The sampling terminal 1 of each of the multiple bidirectional switching switches 26 in the switching switch 26 is turned on and the input terminal 2 is turned off to disconnect the AC signal applied to the electrode plate 10. At the same time, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls each of the grounding switches 25 in a group electrically connected to the electrode plate 10 to be turned on sequentially in a time-division manner. At this time, the temperature detection signals collected by each temperature sensor 14 of each electrode unit 12 in each row of the electrode plate 10 can be collected sequentially in a time-division manner through the multiple detection channels A, B, C, D, E of a group of analog-to-digital converters 23 corresponding to the electrode plate 10. Each detection channel A, B, C, D, E of each group of analog-to-digital converters 23 collects only the temperature detection signal of the temperature sensor 14 of the corresponding electrode unit 12 in each row of the electrode plate 10 at the same time. The temperature detection signal can be characterized by a voltage value. Only one of the four grounding switches 25 in the set corresponding to the electrode 10 can be on at any given time, while the other three are off. All five bidirectional switches 26 in the set corresponding to the analog-to-digital converter 23 are switched to their respective sampling terminals 1, so that each dual-purpose signal line 19 of the electrode 10 is electrically connected to the corresponding detection channels A, B, C, D, and E of the analog-to-digital converter 23. With this configuration, the analog-to-digital converter 23 can acquire the voltage values ​​of all temperature sensors 14 of each electrode unit 12 in the same row group that are short-circuited to one grounding line 18 corresponding to the on-circuit grounding switch 25.

[0085] Specifically, when the first grounding switch 25-1 is closed, and the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4 are all open, and the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 are all switched to their respective sampling terminals 1, the temperature sensors 14 of the electrode units 12-1 to 12-5 of the first row group are energized, and the electrode units 12-6 of the remaining row groups are energized. (See specification page 17 / 33, 20 CN 120983797 A) When the temperature sensors 14 of electrode units 12-20 are de-energized, the signal terminals 14-2 of the temperature sensors 14 of electrode units 12-1, 12-6, 12-11, and 12-16 are short-circuited on the first detection channel A of the analog-to-digital converter 23. Since only the ground terminal 14-1 of the temperature sensor 14 of electrode unit 12-1 is connected to ground, while the ground terminals 14-1 of the temperature sensors 14 of electrode units 12-6, 12-11, and 12-16 are disconnected, and each electrode unit...Each of the 12 electrodes is equipped with a diode 16 connected in series with the temperature sensor 14. The other temperature sensors 14 in the first row do not affect the resistance value of the temperature sensor 14 in electrode unit 12-1. Therefore, only the temperature sensor 14 in electrode unit 12-1 is effectively operating on the first detection channel A of this group of analog-to-digital converters 23. The temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 in electrode unit 12-1. Similarly, the voltage value collected on the second detection channel B of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-2. The voltage value collected on the third detection channel C of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-3. The voltage value collected on the fourth detection channel D of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-4. The voltage value collected on the fifth detection channel E of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-5.

[0086] When the second grounding switch 25-2 is closed, the first grounding switch 25-1, the third grounding switch 25-3, and the fourth grounding switch 25-4 are all open, and the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 are all switched to their respective sampling terminals 1, the temperature sensors 14 of the electrode units 12-6 to 12-10 in the second row group are energized, and the temperature sensors 14 of the electrode units 12-1 to 12-5 and the electrode units 12-11 to 12-20 in the other row groups are de-energized. The signal terminals 14-2 of the temperature sensors 14 of the electrode units 12-1, 12-6, 12-11, and 12-16 in the first detection channel A of the analog-to-digital converter 23 are shorted. Since only the grounding terminal 14-1 of the temperature sensor 14 of the electrode unit 12-6 is connected, the signal terminals 14-2 of the temperature sensors 14 of the electrode units 12-1, 12-6, 12-11, and 12-16 are connected. The grounding terminal 14-1 of the temperature sensor 14 of each of electrode units 12-1, 12-11, and 12-16 is disconnected. Each electrode unit 12 has a diode 16 connected in series with the temperature sensor 14. The other temperature sensors 14 in the second row do not affect the resistance value of the temperature sensor 14 in electrode unit 12-6. Therefore, only the temperature sensor 14 of electrode unit 12-6 is effectively operating on the first detection channel A of this group of analog-to-digital converters 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 of electrode unit 12-6. Similarly, the voltage value collected on the second detection channel B of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-7.The voltage value. The voltage value collected on the third detection channel C in this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-8. The voltage value collected on the fourth detection channel D in this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-9. The voltage value collected on the fifth detection channel E in this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-10.

[0087] When the third grounding switch 25-3 is closed, the first grounding switch 25-1, the second grounding switch 25-2 and the fourth grounding switch 25-4 are all open, and the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, and the third bidirectional switching switch 26- 3. When the fourth bidirectional switching switch 26-4 and the fifth bidirectional switching switch 26-5 are both switched to their respective sampling terminals 1, the temperature sensors 14 of electrode units 12-11 to 12-15 in the third row group are energized, while the temperature sensors 14 of electrode units 12-1 to 12-10 and electrode units 12-16 to 12-20 in the other rows are de-energized. The signal terminals 14-2 of the temperature sensors 14 of electrode units 12-1, 12-6, 12-11, and 12-16 are short-circuited on the first detection channel A of the analog-to-digital converter 23 in this group. Since only the ground terminal 14-1 of the temperature sensor 14 of electrode unit 12-11 is connected to ground, while the ground terminals 14-1 of the temperature sensors 14 of electrode units 12-1, 12-6, and 12-16 are disconnected, and each electrode unit 12 is equipped with a diode 16 connected in series with the temperature sensor 14, located on page 21 of the specification (18 / 33). CN 120983797 A The remaining temperature sensors 14 in the three rows will not affect the resistance value of the temperature sensor 14 in electrode unit 12-11. Therefore, only the temperature sensor 14 in electrode unit 12-11 is effectively working on the first detection channel A of this group of analog-to-digital converters 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 in electrode unit 12-11. Similarly, the voltage value collected by the second detection channel B in this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-12. The voltage value collected by the third detection channel C in this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-13. The voltage value collected by the fourth detection channel D in this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-14. The voltage value collected by the fifth detection channel E in this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-15.

[0088] When the fourth grounding switch 25-4 is closed, and the first grounding switch 25-1, the second grounding switch 25-2, and the third grounding switch 25-3 are all open, and the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 are all switched to their respective sampling terminals 1, the temperature sensors 14 of electrode units 12-16 to 12-20 in the fourth row group are energized, while the temperature sensors 14 of electrode units 12-1 to 12-15 in the other rows are de-energized. The signal terminals 14- of the temperature sensors 14 of electrode units 12-1, 12-6, 12-11, and 12-16 in the first detection channel A of the analog-to-digital converter 23 are short-circuited. 2. Since only the grounding terminal 14-1 of the temperature sensor 14 in electrode unit 12-16 is connected to ground, while the grounding terminals 14-1 of the temperature sensors 14 in electrode units 12-1, 12-6, and 12-11 are disconnected, and each electrode unit 12 has a diode 16 connected in series with the temperature sensor 14, the other temperature sensors 14 in the fourth row will not affect the resistance value of the temperature sensor 14 in electrode unit 12-16. Therefore, only the temperature sensor 14 of electrode unit 12-16 is effectively operating on the first detection channel A of this group of analog-to-digital converters 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 in electrode unit 12-16. Similarly, the voltage value collected on the second detection channel B of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-17. The voltage value collected on the third detection channel C of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-18. The voltage value collected on the fourth detection channel D of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-19. The voltage value collected on the fifth detection channel E of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-20. Thus, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 can collect the temperature detection signals of the temperature sensors 14 of all electrode units 12 of a certain electrode piece 10 by controlling a set of bidirectional switching switches 26 and a set of grounding switches 25 that are electrically connected to a certain electrode piece 10. Similarly, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 of other electrode pieces 10 can be obtained.

[0089] The first controller 22, multiple groups of analog-to-digital converters 23 and multiple groups of bidirectional switching switches 26 can automatically perform operations through pre-programmed program code. For example, the first controller 22 first controls each bidirectional switch in the corresponding group of bidirectional switching switches 26.All switches 26 are switched to sampling terminal 1, making all sampling terminals 1 of these bidirectional switches 26 conductive and all input terminals 2 disconnected, so that each dual-purpose signal line 19 of the corresponding electrode 10 is electrically connected to the corresponding group of analog-to-digital converters 23. Then, the first grounding switch 25-1 in the corresponding group of grounding switches 25 is closed, and the remaining second grounding switches 25-2, third grounding switches 25-3 to fourth grounding switches 25-4 in the group of grounding switches 25 are disconnected. During this period, each detection channel A, B, C of the group of analog-to-digital converters 23 is open. D and E acquire the temperature detection signals of each temperature sensor 14 of each electrode unit 12 located in the first row group of the corresponding electrode sheet 10, convert them into digital signals, and store them in a separately set memory. Then, after a preset interval, the first controller 22 closes the second grounding switch 25-2 in the group of grounding switches 25, and opens the first grounding switch 25-1, the third grounding switch 25-3, and the fourth grounding switch 25-4 in the group of grounding switches 25. During this period, the detection channels A, B, C, D, and E of the group of analog-to-digital converters 23 acquire the temperature detection signals of each temperature sensor 14 of each electrode unit 12 located in the second row group. As per this specification (page 22, CN 120983797 A), by sequentially and individually turning on each grounding switch 25 in the group of grounding switches 25, the temperature detection signals of all temperature sensors 14 in each row group of the electrode sheet 10 can be obtained. Similarly, through this operation, the temperature detection signals of all temperature sensors 14 on at least one pair of electrode sheets 10 can be obtained.

[0090] The tumor electric field therapy system 100 of this application can achieve real-time and comprehensive monitoring of the temperature of all electrode units 12 on the electrode sheet 10 without increasing the weight of the electrode sheet 10 or the number of wire cores of the first cable 13 electrically connected to the electrode sheet 10. It can then determine whether the electrode sheet 10 is qualified based on the obtained temperature detection signal; or determine whether the temperature sensor 14 of the electrode sheet 10 is faulty or abnormal based on the obtained temperature detection signal, and determine whether the electrode sheet 10 needs to be replaced based on the number of faulty or abnormal temperature sensors 14; or, if the electrode sheet is qualified, identify the electrode sheet type based on the obtained temperature detection signal; or, if the electrode sheet is qualified, determine whether the electrode unit 12 of the electrode sheet 10 is overheated based on the obtained temperature detection signal, and then control the alternating electrical signal applied to the electrode sheet 10 or the corresponding column of electrode units 12 of the electrode sheet 10, thereby avoiding low-temperature burns to the patient's body surface during tumor treatment through the electrode sheet 10. Furthermore, the flexible circuit board 11 of the electrode sheet 10 in this application is electrically connected to the dielectric element 15 of the same electrode unit 12 and the signal terminal 14-2 of the temperature sensor 14 simultaneously via the same dual-purpose signal line 19, thereby enabling the transmission of both AC and AC signals via the dual-purpose signal line 19.While simultaneously transmitting the DC signal used for temperature signal acquisition and the acquired temperature detection signal, the number of conductive traces (grounding wire 18, dual-purpose signal line 19) laid on it is greatly reduced, thus lowering the wiring difficulty of the flexible circuit board 11, simplifying the manufacturing process, reducing the weight of the flexible circuit board 11, and lowering manufacturing costs. The electrode sheet 10 of this application can also achieve switching between applying an AC signal for tumor treatment and transmitting the DC signal used for temperature acquisition and transmitting the acquired temperature detection signal through a combination of a grounding switch 25 electrically connected to the grounding wire 18 and a bidirectional switching switch 26 electrically connected to the dual-purpose signal line 19.

[0091] When the electrode pad 10 is properly connected and it is necessary to apply an AC signal to the patient through each electrode unit 12 of a certain electrode pad 10, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls all the grounding switches 25 in a set of grounding switches 25 corresponding to the electrode pad 10 to be disconnected, and at the same time controls all the bidirectional switching switches 26 in a set of bidirectional switching switches 26 corresponding to the electrode pad 10 to be switched to their respective input terminals 2, so that the sampling terminals 1 of these bidirectional switching switches 26 are all disconnected and the input terminals 2 are all turned on, so that each dual-purpose signal line 19 of the electrode pad 10 is electrically connected to an AC signal line 28 corresponding to the adapter 20 and the electrode pad 10, thereby transmitting the AC signal to each electrode unit 12 of the electrode pad 10. When the temperature detection signal of the temperature sensor 14 of all electrode units 12 of the electrode sheet 10 is much lower than the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 controls the AC signal generator 34 through its second controller 32 to continue generating an AC signal with an increased voltage or current amplitude or a constant voltage or current amplitude. Then, the AC signal is transmitted to the corresponding counter electrode 10 via the corresponding AC signal line 28 of the adapter 20, so that the counter electrode 10 continues to be applied with an AC signal; when the temperature detection signal of the temperature sensor 14 of all electrode units 12 of the detected electrode 10 is lower than but close to the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 can reduce the voltage or current of the AC signal generated by the AC signal generator 34 through the second controller 32, thereby reducing the voltage or current of the AC signal applied to the counter electrode 10; when the temperature detection signal of the temperature sensor 14 of the electrode unit 12 of a certain electrode 10 is detected to be greater than the preset temperature threshold, the electric field generator 30 controls the AC signal switch 35 electrically connected to the electrode 10 to disconnect through the second controller 32, so as to stop applying the AC signal to the electrode 10; or the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 controls a set of bidirectional switching switches electrically connected to the electrode 10.All bidirectional switches 26 in the 26 series switch from their input terminal 2 to their sampling terminal 1. That is, all bidirectional switches 26 in a set of bidirectional switches 26 electrically connected to the electrode 10 have their sampling terminals 1 fully turned on and their input terminals 2 fully turned off, thereby stopping the application of alternating electrical signals to the electrode 10. Alternatively, when the temperature detection signal of the temperature sensor 14 of an electrode unit 12 on a certain electrode 10 is detected to be greater than a preset temperature threshold, the second controller 32 of the electric field generator 30 controls the AC signal switch 35 electrically connected to the electrode 10 to continue to be turned on, and the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 controls a bidirectional switch 26 electrically connected to the electrode unit 12 of the electrode 10 to switch from its input terminal 2 to its sampling terminal 1. The first controller 22 of the connector 20 simultaneously controls the input terminals 2 of the remaining bidirectional switching switches 26, which are electrically connected to electrode units 12 in different columns from those electrode units 12 whose temperature detection signals exceed the preset temperature threshold, to remain electrically connected. This stops applying AC signals to all electrode units 12 in the same column as those electrode units 12 whose temperature detection signals exceed the preset temperature threshold, and continues applying AC signals to the remaining column electrode units 12 whose temperature detection signals do not exceed the preset temperature threshold. This achieves a regional control method for applying AC signals based on temperature detection signals in the tumor electric field therapy system 100. When applying AC signals, all grounding switches 25 are disconnected.

[0092] In this embodiment, the grounding switch 25, which is electrically connected to the multiple grounding lines 18 of the electrode 10, and the bidirectional switching switch 26, which is electrically connected to the multiple dual-purpose signal lines 19 of the electrode 10, are both located in the adapter 20. However, in other embodiments, the grounding switch 25, which is electrically connected to the grounding line 18, and the bidirectional switching switch 26, which is electrically connected to the dual-purpose signal lines 19, may also be located on the electrode 10 or in the electric field generator 30, which will not be described in detail here. In addition, the analog-to-digital converter 23 located in the adapter 20 may also be located in the electric field generator 30 and directly controlled by the second controller 32.

[0093] This application also provides other embodiments of the electrode 10. The main difference between the multiple embodiments is the number of electrode units 12 and / or the circuit distribution of the electrode units 12, which will be described below.

[0094] Figure 6 is a circuit connection diagram of the tumor electric field therapy system for the second embodiment of this application, showing the circuit connection diagram between the electrode 10D of the second embodiment and the adapter 20 of the first embodiment shown in Figure 1. The following isThe second embodiment uses the electrode sheet 10D as an example for circuit description. The difference between the electrode sheet 10D and the electrode sheet 10 in the first embodiment lies in the number and circuit arrangement of the electrode units 12. The electrode sheet 10D in this embodiment has 13 of the aforementioned electrode units 12. In terms of electrical connection, the flexible circuit board 11D of the electrode sheet 10D arranges these 13 electrode units 12 in three rows and five columns, with each of the two rows having 5 electrode units 12 and the remaining row having 3 electrode units 12. The flexible circuit board 11D of the electrode sheet 10D embeds 3 grounding lines 18, 5 dual-purpose signal lines 19, 1 grounding trace 171 connected to both the grounding pin of the handshake chip 17 and any grounding line 28, and 1 communication line 172 connected to the communication pin of the handshake chip 17. Each grounding wire 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the corresponding row group. Each dual-purpose signal line 19 is used to short-circuit the dielectric element 15 of each electrode unit 12 in each column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals. One grounding wire 18 connected to the grounding trace 171 also grounds the grounding pin of the handshake chip 17.

[0095] The three grounding wires 18 of the flexible circuit board 11D are the first grounding wire 18-1, the second grounding wire 18-2 and the third grounding wire 18-3. In the three rows of the electrode sheet 10D, the first row group includes electrode units 12-1 to 12-5, the second row group includes electrode units 12-6 to 12-10, and the third row group includes electrode units 12-11 to 12-13. Specifically, the first grounding wire 18-1 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-1 to electrode unit 12-5 in the first row group; the second grounding wire 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-6 to electrode unit 12-10 in the second row group; the third grounding wire 18-3 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-11 to electrode unit 12-13 in the third row group and is also used to ground the grounding pin of the handshake chip 17 through a grounding trace 171 connected to the grounding pin of the handshake chip 17 on page 24 of the specification CN 120983797 A. In short, each grounding wire 18 short-circuits and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group, and one of the grounding wires 18 also short-circuits and grounds the grounding pin of the handshake chip 17.

[0096] The five dual-purpose signal lines 19 of the electrode sheet 10D include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, and...The third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-1, 12-6, and 12-11) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-2, 12-7, and 12-12) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to electrode units 12-3 and 12-8. Each of the three electrode units 12 (12-13) has its own dielectric element 15 and its own temperature sensor 14 signal terminal 14-2. One end of the fourth dual-purpose signal line 19-4 is simultaneously connected to the dielectric element 15 and the signal terminal 14-2 of the respective temperature sensor 14 of the two electrode units 12 (12-4 and 12-9). One end of the fifth dual-purpose signal line 19-5 is simultaneously connected to the dielectric element 15 and the signal terminal 14-2 of the respective temperature sensor 14 of the two electrode units 12 (12-5 and 12-10). In short, each dual-purpose signal line 19 short-circuits the dielectric element 15 and the signal terminal 14-2 of the respective temperature sensor 14 of each electrode unit 12 located in the corresponding column group and connects them to the adapter 20.

[0097] The first grounding switch 25-1, the second grounding switch 25-2, and the third grounding switch 25-3 on the adapter 20 are electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, and the third grounding wire 18-3 of the electrode plate 10D respectively via the first connector 40D. The fourth grounding switch 25-4 is in an idle and disconnected state. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 on the adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5 of the electrode plate 10D respectively via the first connector 40D. A communication transmission line 211 on the adapter 20 is electrically connected to a communication line 172 connected to the communication pin of the handshake chip 17 of the electrode 10D.

[0098] The tumor electric field therapy system formed by the electrode 10D, the adapter 20, and the electric field generator 30 operates in the same way as the aforementioned tumor electric field therapy system 100. The second controller 32 of the electric field generator 30 communicates with the first controller 22 of the adapter 20.A handshake communication signal is sent, and the third grounding switch 25-3, which is electrically connected to the handshake chip 17 of the electrode plate 10, is closed via the first controller 22 of the adapter 20 or by direct control. The handshake chip 17 is powered on. At this time, the first controller 22 sends a handshake communication signal to the handshake chip and confirms that the electrode plate 10 is connected normally after receiving the feedback signal from the handshake chip 17. If no feedback signal is received from the handshake chip 17, it is confirmed that the electrode plate 10 is connected abnormally. When the electrode plate 10 is connected normally, the electric field transmitter 30 or the adapter 20 controls 1) all grounding switches 25 to be opened and the input terminals 2 and sampling terminals 1 of all bidirectional switching switches 26 to be turned on and off, so that all dual-purpose signal lines 19 and AC signal lines 28 are connected. At this time, all electrode units 12 of the electrode plate 10 can apply AC signals; 2) the sampling terminals 1 and input terminals 2 of all bidirectional switching switches 26 are turned on and the grounding switches 25 are turned on in sequence, so that the temperature detection signals of the temperature sensors 14 of each electrode unit 12 of each row group of the electrode plate 10 can be obtained in sequence. Among them, no operation is required for the grounding switch 25 which is in an idle and disconnected state.

[0099] Referring to FIG7, it is a circuit connection diagram of the tumor electric field therapy system of the third embodiment of this application, showing a circuit connection diagram of the electrode plate 10E of the third embodiment and the adapter 20 shown in FIG1. ​​The electrode plate 10E is provided with 13 electrode units 12, just like the electrode plate 10D in the second embodiment, but the specific circuit arrangement is different. The flexible circuit board 11E of the electrode plate 10E also arranges these 13 electrode units 12 in three rows and five columns on the circuit. However, two of the rows have 4 electrode units 12 in each row, and the remaining row has 5 electrode units 12. The flexible circuit board 11E of the electrode sheet 10E is also embedded with 3 grounding lines 18, 5 dual-purpose signal lines 19, 1 grounding trace 171 that is simultaneously connected to the grounding pin of the handshake chip 17 and any grounding line 28, and 1 communication line 172 that is connected to the communication pin of the handshake chip 17. Each grounding line 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the corresponding row group. Each dual-purpose signal line 19 is short-circuited to the dielectric element 15 of each electrode unit 12 in each column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals. One grounding line 18 connected to the grounding trace 171 also grounds the grounding pin of the handshake chip 17.

[0100] The 3 grounding lines 18 of the electrode sheet 10E include a first grounding line 18-1, a second grounding line 18-2 and a third grounding line 18-3. The first row group includes electrode units 12-1 to 12-4, and the second row group includes electrode units 12-5 to 12-4.The third row group includes electrode units 12-9 to 12-13. Specifically, the first grounding line 18-1 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-1 to 12-4 in the first row group; the second grounding line 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-5 to 12-8 in the second row group; and the third grounding line 18-3 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-9 to 12-13 in the third row group, and grounds the grounding pin of the handshake chip 17 through a grounding trace 171 connected to the grounding pin of the handshake chip 17. In short, each grounding line 18 short-circuits and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in each row group, and one grounding line 18 also short-circuits and grounds the grounding pin of the handshake chip 17.

[0101] The five dual-purpose signal lines 19 of the electrode sheet 10E include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode unit 12-1, electrode unit 12-5, and electrode unit 12-9) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode unit 12-2, electrode unit 12-6, and electrode unit 12-10) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode unit 12-3, electrode unit 12-6, and electrode unit 12-10) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode unit 12-3, electrode unit 12-5, and electrode unit 12-10). Each of the three electrode units 12 (electrode units 12-7, 12-11) has its dielectric element 15 and its temperature sensor 14 signal terminal 14-2 connected to both the dielectric element 15 and the temperature sensor 14 signal terminal 14-2 of each of the three electrode units 12 (electrode units 12-4, 12-8, 12-12). One end of the fourth dual-purpose signal line 19-4 is simultaneously connected to both the dielectric element 15 and the temperature sensor 14 signal terminal 14-2 of each of the three electrode units 12 (electrode units 12-4, 12-8, 12-12). One end of the fifth dual-purpose signal line 19-5 is simultaneously connected to both the dielectric element 15 and the temperature sensor 14 signal terminal 14-2 of each electrode unit 12 (12-13). In short, each dual-purpose signal line 19 short-circuits the dielectric element 15 and the temperature sensor 14 signal terminal 14-2 of each electrode unit 12 located in a corresponding column group and connects them to the adapter 20.

[0102] The first grounding switch 25-1, the second grounding switch 25-2, and the third grounding switch 25-3 on the adapter 20 are respectively connected to the first grounding wire 18-1, the second grounding wire 18-2, and the third grounding wire 18-3 of the electrode plate 10E via the first connector 40E.Corresponding to the electrical connection, the fourth grounding switch 25-4 is in an idle / disconnected state. The first bidirectional switch 26-1, second bidirectional switch 26-2, third bidirectional switch 26-3, fourth bidirectional switch 26-4, and fifth bidirectional switch 26-5 on the adapter 20 are electrically connected, respectively, to the first dual-purpose signal lines 19-1, 19-2, 19-3, 19-4, and 19-5 of the electrode plate 10E via the first connector 40E. A communication transmission line 211 on the adapter 20 is electrically connected to the communication line 172, which is connected to the communication pin of the handshake chip 17 of the electrode plate 10E.

[0103] The tumor electric field therapy system formed by the electrode 10E, the adapter 20, and the electric field generator 30 operates in the same manner as the tumor electric field therapy system 100 described on pages 23 / 33 of the previous specification, CN 120983797 A. After the electric field generator 30 controls the adapter 20 to complete handshake communication with the handshake chip 17 of the electrode 10E and confirms that the electrode 10E is connected normally, when all grounding switches 25 are open and the input terminals 2 and sampling terminals 1 of all bidirectional switching switches 26 are closed, all dual-purpose signal lines 19 and AC signal lines 28 are connected, and AC signals can be applied to all electrode units 12. When the sampling terminals 1 and input terminals 2 of all bidirectional switching switches 26 are closed, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25 in sequence. Among them, no operation is required for the grounding switches 25 that are in an idle and open state.

[0104] Referring to FIG8, the electrode sheet 10F of the fourth embodiment has 13 electrode units 12, just like the electrode sheet 10D of the third embodiment. However, the specific circuit layout is different. The flexible circuit board 11F of the electrode sheet 10F arranges these 13 electrode units 12 in four rows and four columns on the circuit, with three rows each having 4 electrode units 12 and the remaining row having 1 electrode unit 12. The electrode sheet 10F includes 4 ground lines 18, 4 dual-purpose signal lines 19, 1 ground trace 171 that is connected to the ground pin of the handshake chip 17 and any ground line 28 at the same time, and 1 communication line 172 that is connected to the communication pin of the handshake chip 17. Each grounding wire 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the corresponding row group. Each dual-purpose signal line 19 is used to short-circuit the dielectric element 15 of each electrode unit 12 in each column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals. One grounding wire 18 connected to the grounding trace 171 also grounds the grounding pin of the handshake chip 17.

[0105] The four grounding wires 18 of the electrode sheet 10F include a first grounding wire 18-1, a second grounding wire 18-2, a third grounding wire 18-1, a fourth grounding wire 18-1, a fifth grounding wire 18-1, a sixth grounding wire 18-1, a seventh grounding wire 18-1, a eleventh ...3 and the fourth grounding wire 18-4. The first row group includes electrode units 12-1 to 12-4, the second row group includes electrode units 12-5 to 12-8, the third row group includes electrode units 12-9 to 12-12, and the fourth row group includes electrode unit 12-13. Specifically, the first grounding wire 18-1 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12-1 to 12-4 in the first row group; the second grounding wire 18-2 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12-5 to 12-8 in the second row group; the third grounding wire 18-3 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12-9 to 12-12 in the third row group; and the fourth grounding wire 18-4 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12-13 in the fourth row group. The fourth grounding line 18-4 is also connected to the grounding trace 171 connected to the grounding pin of the handshake chip 17. In short, each grounding line 18 shorts and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in each row group, and one of the grounding lines 18 also shorts and grounds the grounding pin of the handshake chip 17.

[0106] The four dual-purpose signal lines 19 of the electrode sheet 10F include the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3 and the fourth dual-purpose signal line 19-4. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the four electrode units 12 (electrode units 12-1, 12-5, 12-9, and 12-13) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-2, 12-6, and 12-10) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-3, 12-7, and 12-11) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-4, 12-8, and 12-12) and the signal terminal 14-2 of each of their respective temperature sensors 14. In short, each dual-purpose signal line 19 shorts in parallel the signal terminals 14-2 of the dielectric elements 15 and temperature sensors 14 of each electrode unit 12 located in the same column group and connects them to the adapter 20.

[0107] The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4 on the adapter 20 are electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, the third grounding wire 18-3, and the fourth grounding wire 18-4 of the electrode plate 10F respectively via the first connector 40F. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, and the fourth bidirectional switching switch 26-4 on the adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, and the fourth dual-purpose signal line 19-4 respectively via the first connector 40F. The fifth bidirectional switching switch 26-5 is in an idle and disconnected state. A communication transmission line 211 on the adapter 20 is electrically connected to a communication line 172 connected to the communication pin of the handshake chip 17 of the electrode 10F.

[0108] The working mode of the tumor electric field therapy system formed by the electrode 10F, the adapter 20 and the electric field generator 30 is the same as that of the aforementioned tumor electric field therapy system 100. After the handshake communication is completed with the first controller 22 of the adapter 20 through the handshake chip 17 and the connection of the electrode 10F is confirmed to be normal, when all grounding switches 25 are all open and the input terminals 2 of all bidirectional switching switches 26 are on, all dual-purpose signal lines 19 and AC signal lines 28 are on, and all electrode units 12 are connected to AC signals. When the sampling terminals 1 of all bidirectional switching switches 26 are on, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25 in sequence. Among them, no operation is required for the idle grounding switches 25 and / or the idle bidirectional switching switches 26.

[0109] Referring to FIG9, it is a schematic diagram of the circuit connection between the electrode sheet and the adapter 20 in another embodiment of the tumor electric field therapy system of this application. In terms of electrical connection, the difference between the electrode sheet 10H in this embodiment and the aforementioned electrode sheet is that the number of electrode units 12 and the arrangement of the electrode units 12 in the circuit connection are different. The electrode sheet 10H in this embodiment has 9 electrode units 12. The flexible circuit board 11H of the electrode sheet 10H arranges these 9 electrode units 12 in two rows and five columns in the circuit connection, with one row having 5 electrode units 12 and the other row having 4 electrode units 12. The flexible circuit board 11H of the electrode sheet 10H is embedded with 2 grounding lines 18, 5 dual-purpose signal lines 19, 1 grounding trace 171 that is simultaneously connected to the grounding pin of the handshake chip 17 and any grounding line 28, and 1 communication line 172 that is connected to the communication pin of the handshake chip 17. Each grounding wire 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the corresponding row group, whereinOne grounding wire 18 is also used to ground the grounding pin of the handshake chip 17. Each dual-purpose signal line 19 is short-circuited to the dielectric element 15 of each electrode unit 12 in each row group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals.

[0110] The two grounding wires 18 of the electrode sheet 10H are the first grounding wire 18-1 and the second grounding wire 18-2. In the two rows of the electrode sheet 10H, the first row group includes electrode units 12-1 to 12-5, and the second row group includes electrode units 12-6 to 12-9. Specifically, the first grounding wire 18-1 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-1 to electrode unit 12-5 in the first row group; the second grounding wire 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-6 to electrode unit 12-9 in the second row group, and at the same time, the grounding pin of the handshake chip 17 is grounded through the grounding trace 171 connected to the grounding pin of the handshake chip 17. In short, each grounding wire 18 short-circuits and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in each row group, and one grounding wire 18 also grounds the grounding pin of the handshake chip 17.

[0111] The five dual-purpose signal lines 19 of the electrode sheet 10H include the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4 and the fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the two electrode units 12 (electrode units 12-1 and 12-6) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the two electrode units 12-2 and 12-7 and the signal terminal 14-2 of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric element 15 of each of the two electrode units 12-3 and 12-8 and the signal terminal 14-2 of their respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is simultaneously connected to the dielectric element 15 of each of the two electrode units 12-4 and 12-9 and the signal terminal 14-2 of their respective temperature sensors 14; (Page 25 / 33 of the specification, 28 CN 120983797 A) The signal terminal 14-2 of the temperature sensor 14; one end of the fifth dual-purpose signal line 19-5 is connected to the dielectric element 15 of the electrode unit 12-5 and the signal terminal 14-2 of the temperature sensor 14. In short, each dual-purpose signal line 19 shorts in parallel the dielectric element 15 of each electrode unit 12 located in the corresponding column and the signal terminal 14-2 of its respective temperature sensor 14.And used to connect to adapter 20.

[0112] The first grounding switch 25-1 and the second grounding switch 25-2 on adapter 20 are electrically connected to the first grounding wire 18-1 and the second grounding wire 18-2 of electrode plate 10H respectively through the first connector 40H. The third grounding switch 25-3 and the fourth grounding switch 25-4 are in an idle and disconnected state. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4 and the fifth bidirectional switching switch 26-5 on adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4 and the fifth dual-purpose signal line 19-5 respectively through the first connector 40H. A communication transmission line 211 on the adapter 20 is electrically connected to a communication line 172 connected to the communication pin of the handshake chip 17 of the electrode 10H.

[0113] The working mode of the tumor electric field therapy system formed by the electrode 10H, the adapter 20 and the electric field generator 30 is the same as that of the aforementioned tumor electric field therapy system 100. After the electric field generator 30 controls the adapter 20 to complete the handshake communication with the handshake chip 17 of the electrode 10E and confirms that the electrode 10E is connected normally, when all grounding switches 25 are open and the input terminal 2 of all bidirectional switching switches 26 is on and the sampling terminal 1 is off, all dual-purpose signal lines 19 and AC signal lines 28 are on, and all electrode units 12 are connected to AC signals; when the sampling terminal 1 of all bidirectional switching switches 26 is on and the input terminal 2 is off, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25. Among them, no operation is required for the grounding switches 25 that are in the idle and disconnected state.

[0114] In the preceding embodiments, the number of grounding switches 25 corresponding to each electrode piece 10, 10D, 10E, 10F, and 10H of the adapter 20 is fixed at 4, and the number of bidirectional switching switches 26 corresponding to each electrode piece 10, 10D, 10E, 10F, and 10H is fixed at 5. This allows for the application of various electrode pieces 10, 10D, 10E, 10F, and 10H with different numbers of electrode units 12. However, in some cases, grounding switches 25 and / or bidirectional switching switches 26 may be in an idle or disconnected state, which can complicate the program control. To simplify the control program, specific adapters can be provided corresponding to the number of grounding wires 18 and the number of dual-purpose signal lines 19 of the electrode pieces to avoid the occurrence of grounding switches 25 and / or bidirectional switching switches 26 in an idle or disconnected state, thus facilitating program control. That is, in other embodiments, the number of grounding switches 25 in each group of grounding switches 25 provided on the adapter 20 can be determined according to the circuit connection of each electrode unit 12 of the corresponding electrode plate.The number of rows can be set according to the number of grounding wires 18 on the flexible circuit board of the corresponding electrode sheet; the number of bidirectional switching switches 26 in each group of bidirectional switching switches 26 on the adapter 20 can be set according to the number of columns divided in the circuit connection of each electrode unit 12 of the corresponding electrode sheet, or according to the number of dual-purpose signal lines 19 on the flexible circuit board of the corresponding electrode sheet. Preferably, the number of grounding switches 25 in each group of grounding switches 25 of the adapter 20 is equal to the number of rows of each electrode unit 12 of the corresponding electrode sheet in the circuit connection, or equal to the number of grounding wires 18 on the flexible circuit board of the corresponding electrode sheet; the number of bidirectional switching switches 26 in each group of bidirectional switching switches 26 provided on the adapter 20 is equal to the number of columns of each electrode unit 12 of the corresponding electrode sheet in the circuit connection, or equal to the number of dual-purpose signal lines 19 on the flexible circuit board of the corresponding electrode sheet

[0115] The present invention also provides a temperature detection method for electrode sheet 10 in a tumor electric field therapy system 100. Referring to FIG10, the method includes:

[0116] Step S10: performing handshake communication with the handshake chip 17 of the electrode sheet 10 through the adapter 20 to determine the connection status of the corresponding electrode sheet 10.

[0117] Step S20: When the electrode 10 and the adapter 20 are connected normally, the adapter 20 is used to configure the switching states of each grounding switch 25 and each bidirectional switching switch 26 corresponding to the electrode 10 on pages 26 / 33 of the specification 29 CN 120983797 A, so that the temperature signals detected by each temperature sensor 14 in each row group can be sampled sequentially through the corresponding temperature sampling points.

[0118] The present invention also provides an electrode type identification method. The electrode type identification is performed when all temperature sensors of the electrode are connected normally. In addition to the above steps S10 and S20, the method also includes:

[0119] Step S30: Identify the type of the corresponding electrode 10 according to the temperature signals detected by all temperature sensors 14 of the corresponding electrode 10.

[0120] The temperature signals detected by all temperature sensors 14 of the corresponding electrode 10 sampled in step S30 are temperature analog signals. Step S30 specifically includes the following steps:

[0121] Step S301: Perform digital-to-analog conversion on all sampled temperature analog signals to obtain several AD sampling values;

[0122] Step S302: Determine the number of electrode units 12 of the corresponding electrode sheet 10 according to the several AD sampling values;

[0123] Step S303: Determine the type of the corresponding electrode sheet 10 according to the number of electrode units 12.

[0124] The present invention also provides a method for judging abnormal electrode sheet temperature. The judgment of abnormal electrode sheet temperature is performed during tumor electric field therapy by applying alternating current signals through each electrode unit of the electrode sheet. In addition to the steps mentioned above, this method also includes the following steps.In addition to steps S10 and S20, the following steps are also included:

[0125] Step S40: Determine whether the corresponding electrode 10 has a temperature abnormality based on the temperature signals detected by all temperature sensors of the sampled corresponding electrode.

[0126] Step S40 specifically includes the following steps:

[0127] Step S401: Compare all sampled temperature signals with a preset temperature threshold;

[0128] Step S402: Determine whether the electrode has a temperature abnormality based on the comparison results.

[0129] The comparison results in step S402 include temperature signals less than the preset temperature threshold and temperature signals greater than or equal to the preset temperature threshold. The determination of temperature abnormality is as follows: when there is a temperature signal greater than or equal to the preset temperature threshold among all sampled temperature signals, the electrode temperature is determined to be abnormal; when all sampled temperature signals are less than the preset temperature threshold, the electrode temperature is determined to be normal. The preset temperature threshold is 39℃-44℃, preferably 41℃.

[0130] The present invention also includes an alternating electrical signal adjustment method, which, in addition to steps S10 and S20, further includes: adjusting the alternating electrical signal applied to the corresponding electrode plate according to the temperature signals detected by all temperature sensors of the corresponding electrode plate. The adjustment is to adjust the magnitude of the voltage, current or power of the alternating electrical signal.

[0131] Referring to FIG11, the present invention also provides an electric field control method applied to the tumor electric field therapy system 100, which includes the following steps:

[0132] In step 101, the tumor electric field therapy system 100 is connected.

[0133] Specifically, the four electrode plates 10 are respectively connected to the adapter 20, the adapter 20 is connected to the electric field generator 30, and the electric field generator 30 is connected to a suitable power supply.

[0134] In step 102, it is detected whether the user issues a command to turn on the electric field. If no command to turn on the electric field is detected, step 102 is repeated; if a command to turn on the electric field is detected, step 103 is entered.

[0135] In step 103, after the electric field generator 30 of the tumor electric field therapy system 100 sends a handshake signal to the electrode 10 connected to the X1 port through the second connector 50, the adapter 20, and the first connector 40 connected to the X1 port, the first controller 22 of the adapter 20 receives the feedback signal from the electrode 10 at the X1 port through the corresponding communication transmission line 211, and determines whether the handshake is successful; if it fails, proceed to step 105; if it succeeds, proceed to step 106.

[0136] This determination step can occur in the adapter 20 or the electric field generator 30. In this embodiment, the determination step occurs in the adapter 20. Specifically, when the electrode 10 at the X1 port is connected normally, its handshake chip 17 can receive the electric field generator signal. (Instruction manual pages 27 / 33, 30 CN 120983797 A)The electric field generator 30 sends a handshake request signal and feeds back the handshake status to the first controller 22 of the adapter 20. The first controller 22 determines that the handshake is successful. Conversely, if the electrode 10 at the X1 port is abnormally connected, the first controller 22 of the adapter 20 will not receive the feedback signal from its handshake chip 17, and the first controller 22 will determine that the handshake has failed.

[0137] In step 105, the tumor electric field therapy system 100 issues an alarm due to the handshake failure, and then proceeds to step 101.

[0138] In step 106, after the electric field generator 30 sends a handshake signal to the electrode 10 connected to the X2 port through the second connector 50, the adapter 20, and the first connector 40 connected to the X2 port, the first controller 22 on the adapter 20 receives the feedback signal from the electrode 10 at the X2 port through the corresponding communication transmission line 211, and determines whether the handshake is successful. If it fails, proceed to step 105; if it succeeds, proceed to step 107.

[0139] This judgment step can occur in the adapter 20 or the electric field generator 30. In this embodiment, the judgment step occurs in the adapter 20. Specifically, when the electrode plate 10 at the X2 port is connected normally, its handshake chip 17 can receive the handshake request signal from the electric field generator 30 and feed back the handshake status to the first controller 22 of the adapter 20. The first controller 22 judges that the handshake is successful. Conversely, when the electrode plate 10 at the X2 port is connected abnormally, the first controller 22 of the adapter 20 does not receive the feedback signal from its handshake chip 17, and the first controller 22 judges that the handshake has failed.

[0140] In step 107, after the electric field generator 30 sends a handshake signal to the electrode 10 connected to the Y1 port through the second connector 50, the adapter 20, and the first connector 40 connected to the Y1 port, the first controller 22 on the adapter 20 receives the feedback signal from the electrode 10 at the Y1 port through the corresponding communication transmission line 211, and determines whether the handshake is successful. If it fails, proceed to step 105; if it succeeds, proceed to step 108.

[0141] This determination step can occur in the adapter 20 or the electric field generator 30. In this embodiment, the determination step occurs in the adapter 20. Specifically, when the electrode 10 at the Y1 port is connected normally, its handshake chip 17 can receive the handshake request signal from the electric field generator 30 and feed back the handshake status to the first controller 22 of the adapter 20. The first controller 22 determines that the handshake is successful. Conversely, if the electrode 10 at the Y1 port is abnormally connected, the first controller 22 of the adapter 20 will not receive a feedback signal from its handshake chip 17, and the first controller 22 will determine that the handshake has failed.

[0142] In step 108, after the electric field generator 30 sends a handshake signal to the electrode 10 connected to the Y2 port through the second connector 50, the adapter 20, and the first connector 40 connected to the Y2 port, the first controller 22 on the adapter 20 will, through the phaseThe communication transmission line 211 receives a feedback signal from the electrode 10 at the Y2 port and determines whether the handshake is successful. If it fails, proceed to step 105; if it succeeds, proceed to step 109.

[0143] This determination step can occur in the adapter 20 or the electric field generator 30. In this embodiment, the determination step occurs in the adapter 20. Specifically, when the electrode 10 at the Y1 port is connected normally, its handshake chip 17 can receive the handshake request signal from the electric field generator 30 and feed back the handshake status to the first controller 22 of the adapter 20. The first controller 22 determines that the handshake is successful. Conversely, when the electrode 10 at the Y2 port is connected abnormally, the first controller 22 of the adapter 20 does not receive the feedback signal from its handshake chip 17, and the first controller 22 determines that the handshake has failed.

[0144] In steps 103, 106, 107, and 108 above, after receiving the handshake signal from the tumor electric field therapy system 100, the adapter 20 needs to control the corresponding grounding switch 25 and bidirectional switching switch 26 through the first controller 22, so that the grounding switch 25, which is only electrically connected to the handshake chip 17, is closed, and all other grounding switches 24 are opened, and the sampling terminals 1 and input terminals 2 of the corresponding bidirectional switching switches 26 are all turned on and all are turned off, so that the handshake chip 17 is electrically connected to the grounding pin GND of the adapter 20 through the first connector 40, so that the handshake chip 17 can work normally. If the electric field generator 30 and the adapter 20, the adapter 20 and the adapter 20, and the adapter 20 and the electrode 10 are all normally connected, then the handshake signal issued by the electric field generator 30 can finally reach the handshake chip 17 of the electrode 10, and the handshake status of the handshake chip 17 can be fed back to the electric field generator 30. If at least one connection abnormality occurs between the electric field generator 30 and the adapter 20, between the adapters 20 and each other, or between the adapter 20 and the electrode plate 10 (Instruction manual, pages 28 / 33, 31 CN 120983797 A), the handshake chip 17 will fail to connect VCC and GND to form a circuit, resulting in the adapter 20 and the electric field generator 30 receiving an empty handshake signal, thus causing the handshake to fail.

[0145] In step 109, after the electric field generator 30 of the tumor electric field therapy system 100 sets the electric field parameters, it proceeds to step 110. The electric field parameters include the frequency, voltage, current, or power amplitude of the alternating electrical signal, etc.

[0146] In step 110, the adapter 20 sends temperature reading requests to the first connector 40 at port Y1 and the first connector 40 at port Y2 to collect temperature detection signals corresponding to a total of 40 temperature sensors 14 on the electrode pads 10 at port Y1 and port Y2, and then proceeds to step 111.

[0147] In step 111, the tumor electric field therapy system 100 determines the electric field at port Y1 by collecting the temperature signals.After determining the type of electrode 10 at the Y1 port and the electrode 10 at the Y2 port, the process proceeds to step 112.

[0148] Specifically, the type of electrode 10 at the Y1 port and the electrode 10 at the Y2 port is determined by the number of temperature detection signals of the electrode 10 at the Y1 port and the electrode 10 at the Y2 port, respectively, to determine the number of temperature sensors 14 for each electrode 10. This determination process can occur in the adapter 20 or the electric field generator 30. In this embodiment, the electrode 10 has 20 temperature sensors 14, thus having a total of 40 effective temperature signals.

[0149] In step 112, the tumor electric field therapy system 100 determines whether the temperature signals collected by the adapter 20 are abnormal. If abnormal, the process proceeds to step 114. If all temperature signals are normal, the process proceeds to step 113.

[0150] In step 113, the electric field generator 30 applies an alternating current signal to a pair of electrode plates 10 connected to ports Y1 and Y2, and simultaneously stops applying an alternating current signal to a pair of electrode plates 10 connected to ports X1 and X2, and proceeds to step 115.

[0151] In step 114, the tumor electric field therapy system 100 alarms due to abnormal temperature signals from the electrode plates 10 connected to port Y1 or port Y2, and then immediately proceeds to step 120.

[0152] In step 115, the adapter 20 sends temperature reading requests to the first connector 40 of port X1 and the first connector 40 of port X2 respectively to collect the temperature signals corresponding to all temperature sensors 14 on the electrode plates 10 of port X1 and port X2, and proceeds to step 116.

[0153] In step 116, the tumor electric field therapy system 100 determines the type of the electrode pad 10 at port X1 and port X2 based on the temperature signals and then proceeds to step 117.

[0154] The type of the electrode pad 10 at port X1 and port X2 is determined by determining the number of temperature sensors 14 connected to the electrode pad 10 at port X1 and port X2. This determination process can occur in the adapter 20 or the electric field generator 30. In this embodiment, the electrode pad 10 has 20 temperature sensors 14, thus having a total of 40 valid temperature signals.

[0155] In step 117, the tumor electric field therapy system 100 determines whether the temperature signals collected by the adapter 20 are abnormal. If abnormal, it proceeds to step 114. If all 40 valid temperature signals are normal, it proceeds to step 118.

[0156] In step 118, the electric field generator 30 applies an alternating electrical signal to a pair of electrode plates 10 connected to ports X1 and X2, while simultaneously stopping the application of the alternating electrical signal to the pair of electrode plates 10 connected to ports Y1 and Y2, and proceeds to step 119.113, 115, 116, 117 to 118 have a fixed total time of 1 second.

[0157] In step 119, the tumor electric field therapy system 100 executes subsequent steps based on whether a user has issued a command to turn off the electric field. If a command to turn off the electric field is detected, it proceeds to step 120; if no command to turn off the electric field is detected, it proceeds to step 121.

[0158] In step 120, the tumor electric field therapy system 100 turns off the electric field and proceeds to step 101. At this time, the electric field therapy ends and waits for the next command to turn on the electric field. Specification 29 / 33 pages 32 CN 120983797 A

[0159] In step 121, the tumor electric field therapy system 100 determines whether the electric field parameters need to be adjusted based on the current electric field amplitude and the collected temperature signal. If the electric field parameters need to be adjusted, it proceeds to step 109; if the electric field parameters do not need to be adjusted, it proceeds to steps 110 to 119 in a loop. The total time for steps 118, 119, 121, 110, 111, 112, and 113 is fixed at 1 second in this embodiment. Thus, the tumor electric field therapy system 100 can continuously output alternating electrical signals with a 2-second cycle, alternating between applying an alternating electrical signal in the first direction between a pair of electrodes 10 connected to ports X1 and X2 and an alternating electrical signal in the second direction between another pair of electrode plates 10 connected to ports Y1 and Y2. Simultaneously, the tumor electric field therapy system 100 can reduce the time interval between turning off the alternating electrical signal applied to the pair of electrode plates 10 connected to ports X1 and X2 and turning on the alternating electrical signal applied to the other pair of electrode plates 10 connected to ports Y1 and Y2 to 0 seconds; and reduce the time interval between turning off the alternating electrical signal applied to the other pair of electrode plates 10 connected to ports Y1 and Y2 and turning on the alternating electrical signal applied to the pair of electrode plates 10 connected to ports X1 and X2 to 0 seconds, thereby extending the electric field therapy time while ensuring accurate temperature acquisition.

[0160] This application also provides some temperature detection methods and AC signal application control methods, which are described below using electrode 10 as an example.

[0161] This application embodiment provides an electrode temperature detection method, applied to the above-mentioned electrode 10 or tumor electric field therapy system 100, as shown in FIG12, which includes the following steps:

[0162] Step 210: In the state that the electrode is normally connected after confirming by the handshake chip, control each bidirectional switching switch 26 electrically connected to each electrode unit 12 of the electrode 10 to disconnect the AC signal applied to the dielectric element 15 of each electrode unit 12 of the electrode 10, and at the same time connect the DC signal applied to the signal terminal 14-2 of the temperature sensor 14 of each electrode unit 12 of the electrode 10;

[0163] Step 220: In a time-sequential manner, turn on the grounding switch 25 that is electrically connected to the grounding terminal 14-1 of the temperature sensor 14 of each row group electrode unit 12 of the electrode sheet 10, so as to obtain the temperature detection signal of the temperature sensor 14 of each electrode unit 12 of the electrode sheet 10.

[0164] Step 210 is specifically: control the bidirectional switching switch 26 electrically connected to each electrode unit 12 of the electrode sheet 10 to switch from the end connected to the AC signal to the end connected to the DC signal, that is, control the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch from its input terminal 2 to its sampling terminal 1; or

[0165] control the bidirectional switching switch 26 electrically connected to each electrode unit 12 of the electrode sheet 10 to switch the dielectric element 15 of each electrode unit 12 of the electrode sheet 10 from the on state to the off state, and at the same time switch the signal terminal 14-2 of the temperature sensor 14 of each electrode unit 12 of the electrode sheet 10 from the off state to the on state.

[0166] The electrode temperature detection method of this application can quickly and accurately obtain the temperature detection signals of all electrode units of the electrode sheet; and can determine whether the temperature sensors of the electrode sheet are faulty, abnormal, or whether the electrode sheet is qualified and needs to be replaced based on the obtained temperature detection signals of all temperature sensors of the electrode sheet; can also determine whether each electrode unit of the electrode sheet is overheated based on the obtained temperature detection signals of all temperature sensors of the electrode sheet when all temperature sensors of the electrode sheet are normal, and then control the AC signal applied to the electrode sheet or applied to each electrode unit of the electrode sheet; can also identify the electrode sheet type when the temperature detection signals of all temperature sensors of the electrode sheet are normal.

[0167] Referring to Figure 13, this application embodiment also provides a method for controlling the application of alternating current signals for tumor electric field therapy, which includes the above-mentioned steps 210 and 220, and after step 220, it further includes:

[0168] Step 260: When it is determined that the electrode 10 does not need to be replaced, the alternating current signals applied to each electrode unit 12 of the electrode 10 are controlled or adjusted according to the temperature detection signals of the temperature sensors 14 of each electrode unit 12 of the electrode 10.

[0169] Step 260, controlling or adjusting the AC signal applied to each electrode unit 12 of the electrode sheet 10, further includes:

[0170] Step 261: When the acquired temperature detection signals of each electrode unit 12 of the electrode sheet 10 do not exceed the preset temperature threshold, continue to apply AC signals to each electrode unit 12 of the electrode sheet 10; or

[0171] Step 262: When any of the acquired temperature detection signals of all electrode units 12 of the electrode sheet 10 exceeds the preset temperature threshold, stop applying AC signals to the electrode units 12 of the electrode sheet 10.

[0172] The step 262, which involves stopping the application of AC signals to the electrode units 12 of the electrode sheet 10, includes stopping the application of AC signals to all electrode units 12 of the electrode sheet 10, stopping the application of AC signals to electrode units 12 in the electrode sheet 10 whose temperature detection signals exceed a preset temperature threshold, and stopping the application of AC signals to all electrode units 12 in the same column as the electrode units 12 in the electrode sheet 10 whose temperature detection signals exceed the preset temperature threshold.

[0173] When the application of AC signals to the electrode units 12 in the electrode sheet 10 whose temperature detection signals exceed the preset temperature threshold is stopped, the electrode units 12 in the electrode sheet 10 whose temperature detection signals do not exceed the preset temperature threshold continue to be applied AC signals.

[0174] When the application of AC signals to all electrode units 12 in the same column as the electrode units 12 in the electrode sheet 10 whose temperature detection signals exceed the preset temperature threshold is stopped, the electrode units 12 in the electrode sheet 10 whose temperature detection signals do not exceed the preset temperature threshold and are in a different column from the electrode units 12 whose temperature detection signals exceed the preset temperature threshold continue to be applied AC signals.

[0175] The process of continuing to apply an AC signal to the electrode plate 10 in step 261 is as follows:

[0176] Step 263: When the temperature detection signal is much lower than the preset temperature threshold, continue to apply an AC signal to each electrode unit 12 of the electrode plate 10 by increasing the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode plate 10, or continue to apply an AC signal to each electrode unit 12 of the electrode plate 10 by keeping the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode plate 10 unchanged; or

[0177] Step 264: When the temperature detection signal is close to the preset temperature threshold, continue to apply an AC signal to each electrode unit 12 of the electrode plate 10 by keeping the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode plate 10 unchanged, or continue to apply an AC signal to each electrode unit 12 of the electrode plate 10 by decreasing the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode plate 10.

[0178] Referring to Figure 14, this application also provides a signal control method for tumor electric field therapy, used for the above-mentioned electrode sheet 10. The method includes:

[0179] Step 310: Combining control of a set of grounding switches 25 and a set of bidirectional switching switches 26 electrically connected to the corresponding electrode sheet 10 to apply an AC signal to each electrode unit 12 of the electrode sheet 10 and executing step 320;

[0180] Step 320: Combining control of a set of grounding switches 25 and a set of bidirectional switching switches 26 electrically connected to the electrode sheet 10 to collect temperature detection signals of each electrode unit of the electrode sheet 10 in a row and executing step 330;

[0181] Step 330: Determining a set of grounding switches 25 electrically connected to the electrode sheet 10 based on the collected temperature detection signals.The combined control method with a set of bidirectional switching switches 26 and the execution of step 340;

[0182] Step 340: Control the working state of each electrode unit 12 of the electrode sheet 10 according to the determined combined control method of grounding switch 25 and bidirectional switching switch 26.

[0183] The working state of each electrode unit 12 of the electrode sheet 10 mentioned in step 340 includes: stopping the application of AC signal and continuing to collect temperature detection signal, and stopping the collection of temperature detection signal and continuing to apply AC signal. Continuing to apply AC signal includes continuing to apply AC signal by increasing the voltage or current amplitude of the currently applied AC signal, continuing to apply AC signal by keeping the voltage or current amplitude of the currently applied AC signal unchanged, and continuing to apply AC signal by decreasing the voltage or current amplitude of the currently applied AC signal.

[0184] The working state of each electrode unit 12 of the electrode sheet 10 is determined by the temperature detection signal it collects. Each electrode unit 12 of the electrode sheet 10 is divided into different regions. Each electrode unit 12 in each region can be cyclically switched between applying an AC signal and acquiring a temperature detection signal by a combination of grounding switch 25 and bidirectional switching switch 26.

[0185] This application embodiment provides another method for detecting the temperature of an electrode sheet in a tumor electric field therapy system. Referring to FIG15, taking electrode sheet 10 as an example, the temperature detection method includes:

[0186] Step 510: Disconnect the input of AC power signal to electrode sheet 10, perform combined control of multiple grounding switches 25 and multiple bidirectional switching switches 26, and obtain the temperature detection signal of the temperature sensor 14 of electrode sheet 10 corresponding to each combination;

[0187] Step 520: Sample and convert the temperature detection signal detected by each temperature sensor 14 in electrode sheet 10 to obtain a digital temperature signal;

[0188] Step 530: Transmit the digital temperature signal to the electric field generator 30 of tumor electric field therapy system 100 so that the electric field generator 30 can determine the temperature at the corresponding electrode unit 12 according to the digital temperature signal.

[0189] In step 510, "combined control of multiple grounding switches 25 and multiple bidirectional switching switches 26" specifically includes:

[0190] Step 511: Place all bidirectional switching switches 26 at sampling terminal 1 to conduct the electrical connection between the signal terminals 14-2 of each temperature sensor 14 of each electrode unit 12 and the corresponding analog-to-digital converter 23;

[0191] Step 512: Sequentially close one of the multiple grounding switches 25 individually to collect the temperature detection signals detected by the temperature sensors 14 of each electrode unit 12 in the corresponding row group.

[0192] In step 512, sequentially closing one of the multiple grounding switches 25 individually allows the analog-to-digital converter 23 to connect with the closed switch.The detection channels of each temperature sensor 14 in the row group corresponding to the grounding switch 25 are electrically connected and turned on.

[0193] Thus, the temperature detection signals of each temperature sensor 14 in each row group can be obtained in sequence, and then processed by the adapter 20 or the electric field generator 30 to obtain the temperature corresponding to all electrode units 12 on the electrode sheet 10; thereby making the temperature detection of the patient's body surface more comprehensive and accurate.

[0194] For the tumor electric field therapy system 100 of this application embodiment, the temperature of a single electrode unit 12 can also be detected as needed. The specific process of the method for detecting the temperature of a certain electrode unit 12 of the electrode sheet 10 is as follows: disconnect the input of the AC signal, place the bidirectional switching switch 26 corresponding to the column group where the electrode unit 12 that needs to be measured individually is located at the sampling end 1, and place the remaining bidirectional switching switches 26 at the input end 2; at the same time, turn on and ground the grounding switch 25 corresponding to the row group where the electrode unit 12 that needs to be measured individually is located, and turn off all the remaining grounding switches 25. Therefore, the temperature detection signal of the temperature sensor 14 in the electrode unit 12 that needs to be measured separately can be sampled to obtain the temperature of the electrode unit 12. For example, the electrode unit 12 that needs to be measured separately is electrode unit 12-1. At this time, the first bidirectional switching switch 26-1 corresponding to electrode unit 12-1 is placed at the sampling end 1, and the remaining bidirectional switching switches (second bidirectional switching switch 26-2, second bidirectional switching switch 26-3, third bidirectional switching switch 26-3 and fourth bidirectional switching switch 26-4) are all placed at the input end 2; at the same time, the first grounding switch 25-1 corresponding to electrode unit 12-1 is closed and grounded, and the remaining grounding switches (second grounding switch 25-2, third grounding switch 25-3 and fourth grounding switch 25-4) are all opened. Therefore, the temperature of electrode unit 12-1 can be detected.

[0195] This application embodiment also provides another method for applying an alternating current signal for tumor electric field therapy, applied to the above-mentioned tumor electric field therapy system, and the tumor electric field therapy system 100 in FIG1 is used as an example for description. Please refer to Figure 16. The AC signal application method described on pages 32 / 33 of this specification (CN 120983797 A) includes:

[0196] Step 610: Determine the area of ​​the electrode unit 12 in the electrode plate 10 where the AC signal needs to be applied;

[0197] Step 611: Combine and control multiple grounding switches 25 and multiple bidirectional switching switches 26 electrically connected to the electrode plate 10 to apply the AC signal.

[0198] Step 611, "combining and controlling multiple grounding switches 25 and multiple bidirectional switching switches 26 electrically connected to the electrode plate 10", specifically means:

[0199] Step 612: Disconnect all grounding switches 25 electrically connected to the electrode plate 10;

[0200] Step 613: Determine the column group where the electrode unit 12 to which the AC signal needs to be applied is located, based on the area where the electrode unit 12 to which the AC signal needs to be applied is located;

[0201] Step 614: Determine the bidirectional switching switch 26 electrically connected to the electrode unit 12 in the column group based on the determined column group where the electrode unit 12 to which the AC signal needs to be applied is located;

[0202] In step 610: Divide every four adjacent electrode units 12 in the electrode sheet 10 into a region, and the four electrode units 12 in each region correspond to a column group, connected to a dual-purpose signal line 19 corresponding to the same bidirectional switching switch 26. In other embodiments, the electrode units 12 may be divided in other ways, which will not be described here.

[0203] Step 615: Control the bidirectional switching switch 26 electrically connected to the electrode unit 12 that needs to be applied with an AC signal to connect the electrode unit 12 that needs to be applied with an AC signal to the AC signal line 28 to apply an AC signal; at the same time, control the remaining bidirectional switching switches 26 to disconnect the electrical connection between each electrode unit 12 in the area where no AC signal needs to be applied and the AC signal line 28, thereby stopping the application of AC signals.

[0204] In step 615, "connecting the electrode unit that needs to be applied with an AC signal to the AC signal line 28 to apply an AC signal and disconnecting the electrical connection between the electrode unit 12 in the area where no AC signal needs to be applied and the AC signal line 28 to stop the application of AC signals" is achieved by placing the bidirectional switching switch 26 electrically connected to the electrode unit 12 in the column group corresponding to the area in the electrode sheet 10 where an AC signal needs to be applied at its input terminal 2, and placing all the bidirectional switching switches 26 electrically connected to the electrode unit 12 in the remaining column groups at the sampling terminal 1.

[0205] When the above methods are applied to electrode plates 10D, 10E, 10F, and 10H in other embodiments, since there are grounding switches 25 and / or bidirectional switching switches 26 in an idle and disconnected state on the adapter 20 that are not electrically connected to the corresponding electrode plates 10D, 10E, 10F, and 10H, the corresponding grounding switches 25 and / or bidirectional switching switches 26 in an idle and disconnected state do not need to be controlled.

[0206] Although the various operations are depicted in the drawings in a specific order, this should not be construed as requiring these operations to be performed in the specific order shown or in chronological order, nor should it be construed as requiring all the operations shown to be performed to obtain the desired result.

[0207] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this application, and not to limit them; although this application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or some or all of the technical features can be modified.Equivalent substitutions are permitted; however, these modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions in the embodiments of this application, and they should all be covered within the scope of the claims and specification of this application. In particular, as long as there is no structural conflict, the various technical features mentioned in the embodiments can be combined in any way. This application is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims. Instruction manual, page 33 / 33; 36 CN 120983797 A; Figure 1; Instruction manual, Figure 1 / 13; 37 CN 120983797 A; Figure 2; Instruction manual, Figure 2 / 13; 38 CN 120983797 A; Figure 3; Instruction manual, Figure 3 / 13; 39 CN 120983797 A; Figure 4; Instruction manual, Figure 4 / 13; 40 CN 120983797 A; Figure 5; Instruction manual, Figure 5 / 13; 41 CN 120983797 A; Figure 6; Instruction manual, Figure 6 / 13; 42 CN 120983797 A; Figure 7; Instruction manual, Figure 7 / 13; 43 CN 120983797 A; Figure 8; Instruction manual, Figure 8 / 13; 44 CN 120983797 A; Figure 9; Figure 10; Instruction manual, Figure 9 / 13; 45 CN 120983797 A; Figure 11 Instruction Manual Figures 10 / 13 Page 46 CN 120983797 A Figure 12 Figure 13 Instruction Manual Figures 11 / 13 Page 47 CN 120983797 A Figure 14 Figure 15 Instruction Manual Figures 12 / 13 Page 48 CN 120983797 A Figure 16 Instruction Manual Figures 13 / 13 Page 49 CN 120983797 A Abstract Abdominal ultrasound examination method, system and device Abstract The invention provides an electrode array and a tumor electric field therapy system. The electrode array is provided with a flexible circuit board, a plurality of electrode units and a handshake chip, and the electrodeunit comprises a dielectric element and a temperature sensor with a signal end and a grounding end. The plurality of electrode units are arranged on the flexible circuit board in a space structure with multi-row and multi-column pattern to form at least one main trunk and a plurality of branches extending laterally from the main trunk and each having a free tail end. The plurality of electrode units are arranged in multiple rows and multiple columns on the circuit, the grounding ends in the same row group are connected to the same grounding wire on the flexible circuit board, and the dielectric elements and the signal ends in the same column group are connected to the same dual-purpose signal wire on the flexible circuit board. The dual-purpose signal wires transmit an alternating current signal to the dielectric elements in a first mode and transmit temperature signals detected by each temperature sensor in a second mode, and each grounding wire is disconnected in the first mode andis sequentially and independently connected in the second mode.

Claims

1. An electrode pad used in a tumor electric field therapy system, characterized in that, The electrode sheet has a flexible circuit board, a plurality of electrode units disposed on the flexible circuit board, and a handshake chip. Each electrode unit includes a dielectric element and a temperature sensor with a signal terminal and a ground terminal. The dielectric element is short-circuited to the signal terminal of the temperature sensor. The plurality of electrode units are arranged in a multi-row, multi-column, spaced configuration on the flexible circuit board to form at least one main trunk and several branches extending laterally from the main trunk with free ends. The flexible circuit board has multiple ground lines and multiple dual-purpose signal lines connecting each electrode unit. The plurality of electrode units are also arranged in a multi-row, multi-column configuration in the circuit. The ground terminals of each temperature sensor located in the same row are connected to the same ground line, while those located in different rows are connected to the same ground line. The grounding terminals of the temperature sensors are connected in parallel through different grounding lines. The signal terminals of each temperature sensor in the same column are connected to the same dual-purpose signal line, while the signal terminals of each temperature sensor in different columns are connected in parallel through different dual-purpose signal lines. The electrode has a first mode for applying an AC signal and a second mode for temperature acquisition. In the first mode, each dual-purpose signal line transmits an AC signal to each dielectric element and in the second mode, it transmits the temperature signal detected by each temperature sensor. Each grounding line is disconnected in the first mode and sequentially turned on individually in the second mode. The handshake chip is configured to determine the connection status of the electrode through handshake communication.

2. The electrode sheet according to claim 1, characterized in that, The electrode units include twenty electrode units arranged in a four-row, six-column spatial structure, wherein the backbone includes electrode units located in the third and fourth columns and connecting portions longitudinally connecting adjacent electrode units located in the third and fourth columns.

3. The electrode sheet according to claim 2, characterized in that, From a spatial structure perspective, the two adjacent electrode units located in the third and fourth columns of each row are arranged in a disconnected manner.

4. The electrode sheet according to claim 3, characterized in that, The electrode sheet is provided with a wiring part, which is installed between the main branches.

5. The electrode sheet according to claim 1, characterized in that, The electrode units include twenty electrode units arranged in a four-row, six-column spatial structure, wherein the main structure includes electrode units located in the third and fifth columns and connecting portions longitudinally connecting adjacent electrode units located in the third and fourth columns.

6. The electrode sheet according to claim 5, characterized in that, The electrode sheet is provided with a wiring portion, which is mounted between two electrode units located in the third and fourth columns of one row.

7. The electrode sheet according to claim 2 or 5, characterized in that, The twenty electrode units are arranged in four rows and five columns on the circuit, and the flexible circuit board is provided with four grounding lines and five dual-purpose signal lines.

8. The electrode sheet according to claim 1, characterized in that, The flexible circuit board is provided with a ground trace and a communication line. The handshake chip has a ground pin electrically connected to the ground trace and a communication pin electrically connected to the communication line. The ground pin is connected to one of the multiple ground lines through the ground trace.

9. A tumor electric field therapy system, characterized in that, It includes at least one pair of electrode plates as described in any one of claims 1 to 8 and an electric field generator that provides an alternating current signal to the electrode plates.

10. The tumor electric field therapy system according to claim 9, characterized in that, The electric field generator is equipped with a set of analog-to-digital converters with multiple detection channels, multiple grounding switches, and multiple bidirectional switching switches corresponding to the electrode plates. Each grounding wire of the electrode plate is grounded through a corresponding grounding switch, and each dual-purpose signal line of the electrode plate is electrically connected to a corresponding bidirectional switching switch. The bidirectional switching switch has an input terminal for receiving AC signals and a sampling terminal electrically connected to a corresponding detection channel. In the first mode, each of the bidirectional switching switches is turned on at its input terminal and each of the grounding switches is turned off; in the second mode, each of the bidirectional switching switches is turned on at its sampling terminal and each of the grounding switches is turned on individually in sequence.

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