Electric field generator, tumor electric field therapy system, method for detecting temperatures and over-temperatures of electrode pads

Abstract

The invention provides an electric field generator, a tumor electric field treatment system, an electrode plate temperature detection method and an electrode plate overtemperature detection method. The electric field generator is electrically connected with the electrode plate, the electrode plate comprises a flexible circuit board and a plurality of electrode units which are arranged on the flexible circuit board and are arranged in multiple rows and multiple columns in a circuit, each electrode unit is provided with a dielectric element and a temperature sensor, and the flexible circuit board is provided with multiple paths of grounding wires and multiple paths of dual-purpose signal wires. Each grounding wire is in short circuit connection with the grounding end of each temperature sensor in the corresponding row, and each dual-purpose signal wire is connected with the dielectric element of each electrode unit in the corresponding column and the signal end of each temperature sensor. The electric field generator is provided with a plurality of grounding switches which are respectively connected with the grounding wires in series and a plurality of bidirectional change-over switches which are respectively connected with the dual-purpose signal wires in series; the dual-purpose signal line is connected with an alternating-current electric signal or a direct electric signal in a switching mode through the bidirectional change-over switch so that the electrode unit can be switched between applying the alternating-current electric signal in the first mode and detecting the temperature in the second mode.

Description

(19) State Intellectual Property Office (12) Invention Patent Application (10) Application Publication Number (43) Application Publication Date (21) Application Number 202511686712.8 (22) Application Date 2024.10.25 (66) Domestic Priority Data 202311809226.1 2023.12.26 CN PCT / CN2023 / 142515 2023.12.27 CN (62) Divisional Application Data 202411498459.9 2024.10.25 (71) Applicant Jiangsu Hailai Xinchuang Medical Technology Co., Ltd. Address 214100, 7th Floor, Building 7, Area A and Area B, No. 1699 Huishan Avenue, Huishan Economic Development Zone, Wuxi City, Jiangsu Province Applicant: Hangzhou Hailai Xinchuang Medical Technology Co., Ltd. (72) Inventor: Shen Qichao, Ying Jianjun, Yu Jinghui, Jiajie (request not to disclose name) Hu Tao (51) Int.Cl. A61N 1 / 36 (2006.01) A61N 1 / 04 (2006.01) G01K 13 / 00 (2021.01) G01K 13 / 20 (2021.01) G01N 25 / 00 (2006.01) G01R 31 / 00 (2006.01) H01R 13 / 70 (2006.01) (54) Invention Title: Electric Field Generator, Tumor Electric Field Therapy System, Electrode Temperature Detection Method and Electrode Overheat Detection Method (57) Abstract: This application provides an electric field generator, a tumor electric field therapy system, an electrode temperature detection method and an electrode overheat detection method. The electric field generator is electrically connected to the electrode sheet, which includes a flexible circuit board and multiple electrode units arranged in multiple rows and columns on the flexible circuit board. Each electrode unit has a dielectric element and a temperature sensor. The flexible circuit board has multiple grounding wires and multiple dual-purpose signal lines. Each grounding wire is short-circuited to the grounding terminal of each temperature sensor in the corresponding row. Each dual-purpose signal line is connected to the signal terminal of the dielectric element and temperature sensor of each electrode unit in the corresponding column. The electric field generator has multiple grounding switches connected in series with each grounding wire and multiple bidirectional switching switches connected in series with each dual-purpose signal line. The dual-purpose signal lines are connected to AC signals or direct electrical signals via the bidirectional switching switches, allowing the electrode units to switch between applying AC signals in the first mode and detecting temperature in the second mode. Claims (3 pages), Description (41 pages), Drawings (19 pages), CN 121288197 A 2026.01.09 CN 1 21 28 81 97 A 1. An electric field generator, characterized in that: it is used to provide an alternating current signal to an electrode plate of a tumor electric field therapy system, wherein the electrode plate includes a flexible circuit board having multiple grounding wires and multiple dual-purpose signal lines therein, and a circuit board disposed on the flexible wires.The circuit board has multiple electrode units, each equipped with a dielectric element for applying an AC signal and a temperature sensor for detecting temperature, having both a ground terminal and a signal terminal. The signal terminal of the temperature sensor in each electrode unit is short-circuited to its dielectric element. The electrode units are configured in multiple row groups and multiple column groups. The ground terminals of the temperature sensors of each electrode unit in the same row group are all short-circuited via the same grounding wire. The ground terminals of the temperature sensors of each electrode unit in different row groups are connected in parallel via different grounding wires. The dielectric element and the signal terminal of the temperature sensor in each electrode unit in the same column group are all short-circuited via the same dual-purpose signal line. The dielectric element and the signal terminal of the temperature sensor of each electrode unit located in different columns are respectively connected in parallel through different dual-purpose signal lines; the electric field generator is provided with multiple grounding switches and multiple bidirectional switching switches corresponding to the electrode plates, wherein each grounding wire of the electrode plate is grounded through a corresponding grounding switch, each dual-purpose signal line is electrically connected to a corresponding bidirectional switching switch, and each dual-purpose signal line switches between receiving an AC signal in a first mode and receiving a DC signal in a second mode through the bidirectional switching switch connected in series with it. The electrode unit applies an AC signal through its dielectric element in the first mode and detects the temperature through its temperature sensor in the second mode. 2. The electric field generator according to claim 1, wherein the bidirectional switching switch is provided with an input terminal for receiving an AC signal and a acquisition terminal for receiving a DC signal, the bidirectional switching switch conducts its input terminal in the first mode and conducts its acquisition terminal in the second mode. 3. The electric field generator according to claim 1, characterized in that the number of grounding switches is greater than or equal to the number of grounding wires, and / or the number of bidirectional switching switches is greater than or equal to the number of dual-purpose signal lines. 4. The electric field generator according to claim 3, characterized in that among the plurality of grounding switches, there are grounding switches that are in an idle / disconnected state; and / or among the plurality of bidirectional switching switches, there are bidirectional switching switches that are in an idle / disconnected state. 5. The electric field generator according to claim 1, characterized in that it is provided with an analog-to-digital converter, the analog-to-digital converter having a plurality of detection channels, the acquisition terminal of each bidirectional switching switch being electrically connected to a corresponding detection channel, and the analog-to-digital converter sampling the temperature detection signals of each temperature sensor. 6. The electric field generator according to claim 5, characterized in that it is provided with an AC signal line, and the input terminal of each bidirectional switching switch being electrically connected to the AC signal line. 7. The electric field generator according to claim 1, characterized in that the electric field generator is configured as: a combined control...The grounding switch and the bidirectional switching switch are configured to (1) transmit AC signals to the dielectric elements of the electrode units via the dual-purpose signal lines in a first mode; and (2) transmit DC signals to the signal terminals of the temperature sensors of the electrode units via the dual-purpose signal lines or transmit temperature detection signals detected by the temperature sensors of the electrode units via the dual-purpose signal lines in a second mode. 8. The electric field generator according to claim 7, wherein the electric field generator is further configured to: determine the operating state of the electrode units based on the temperature detection signals of the temperature sensors. 9. The electric field generator according to claim 8, characterized in that the electric field generator has a preset temperature threshold and is further configured to: when none of the temperature detection signals exceed the preset temperature threshold, combine and control each of the grounding switches and each of the bidirectional switching switches to transmit AC electrical signals to the dielectric elements of each of the electrode units through each of the dual-purpose signal lines; when one of the temperature detection signals exceeds the preset temperature threshold, combine and control each of the grounding switches and each of the bidirectional switching switches to stop the transmission of the AC electrical signals. 10. The electric field generator according to claim 9, wherein the electric field generator is further configured to: when all the temperature detection signals are much lower than the preset temperature threshold, combine and control each of the grounding switches and each of the bidirectional switching switches to transmit an AC signal with increased intensity or constant intensity to the dielectric element of each of the electrode units through each of the dual-purpose signal lines; when there is a temperature detection signal close to the preset temperature threshold, combine and control each of the grounding switches and each of the bidirectional switching switches to transmit an AC signal with constant intensity or decreased intensity to the dielectric element of each of the electrode units through each of the dual-purpose signal lines. 11. The electric field generator according to claim 9, wherein stopping the transmission of the AC signal includes stopping the transmission of AC signals to the dielectric elements of all the electrode units and stopping the transmission of AC signals to each of the electrode units in the column containing the electrode units exceeding the preset temperature threshold. 12. The electric field generator according to claim 1, characterized in that the electric field generator has a first preset temperature and a preset temperature threshold, the first preset temperature being less than the preset temperature threshold, and the electric field generator is configured to: compare each of the temperature detection signals with the first preset temperature; and control the intensity of the AC signal transmitted to the dielectric element of each of the electrode units according to the comparison result. 13. The electric field generator according to claim 11, characterized in that the electric field generator is further configured to: when each of the temperature detection signals is less than the first preset temperature, combine and control each of the grounding switches and each of the electrode units...The bidirectional switching switch enables each of the dual-purpose signal lines to transmit AC signals with increased or constant intensity to the dielectric elements of each of the electrode units; when a temperature detection signal is greater than the first preset temperature and all temperature detection signals are less than the preset temperature threshold, the grounding switch and the bidirectional switching switch are controlled in combination to enable each of the dual-purpose signal lines to transmit AC signals with constant or decreased intensity to the dielectric elements of each of the electrode units; when a temperature detection signal is greater than the preset temperature threshold, the grounding switch and the bidirectional switching switch are controlled in combination to enable all dual-purpose signal lines to stop transmitting AC signals to the dielectric elements of each of the electrode units; or to enable the dual-purpose signal line corresponding to the column group of the electrode unit where the temperature detection signal exceeds the preset temperature threshold to stop transmitting AC signals and enable the remaining dual-purpose signal lines to transmit AC signals. 14. The electric field generator according to claim 1, wherein the electric field generator is further configured to: combine and control each of the grounding switches and each of the bidirectional switching switches to stop transmitting AC signals to the dielectric elements of each of the electrode units and to stop transmitting DC signals to the temperature sensors of each of the electrode units. 15. A tumor electric field therapy system, characterized in that it comprises: an electrode sheet, the electrode sheet including a flexible circuit board having multiple grounding wires and multiple dual-purpose signal lines therein, and multiple electrode units disposed on the flexible circuit board, each electrode unit having a dielectric element for applying an alternating current signal and a temperature sensor for detecting temperature and having a grounding terminal and a signal terminal, wherein the signal terminal of the temperature sensor of the electrode unit is short-circuited with its dielectric element; the multiple electrode units are configured in the circuit as multiple row groups and multiple column groups, the grounding terminals of the temperature sensors of each electrode unit located in the same row group are all short-circuited through the same grounding wire, and the grounding terminals of the temperature sensors of each electrode unit located in different row groups are respectively connected in parallel through different grounding wires; the dielectric element and the temperature sensor of each electrode unit located in the same column group are also connected in parallel. The signal terminals of each electrode unit located in different columns are all shorted through the same dual-purpose signal line, and the signal terminals of the dielectric element and the temperature sensor are respectively connected in parallel through different dual-purpose signal lines; and an electric field generator as described in any one of claims 1 to 13. 16. An electrode temperature detection method, characterized in that it is applied to an electric field generator as described in any one of claims 1 to 13 or a tumor electric field therapy system as described in claim 14, the method comprising: controlling each of the bidirectional switching switches of the electric field generator to disconnect the dielectric element applied to each electrode unit.The AC signal on the electrical component is simultaneously connected to the DC signal applied to the signal terminal of the temperature sensor of each of the electrode units; the grounding switches of the electric field generator are sequentially and individually turned on to obtain the temperature detection signal of the temperature sensor of each of the electrode units. 17. The method according to claim 15, characterized in that, based on the obtained temperature detection signal of each temperature sensor of the electrode sheet, at least one of the following situations is determined: (1) whether the temperature sensor of the electrode sheet is faulty or abnormal; (2) whether the electrode sheet is qualified; (3) whether the electrode sheet needs to be replaced; (4) if the electrode sheet is qualified, the type of the electrode sheet is identified; (5) if the electrode sheet is qualified, it is determined whether the electrode unit of the electrode sheet is over-temperature. 18. A method for detecting overheating of an electrode sheet, characterized in that: it is applied to an electric field generator as described in any one of claims 1-13 or a tumor electric field therapy system as described in claim 14, the method comprising: combining and controlling each of the grounding switches and each of the bidirectional switching switches of the electric field generator to enable each of the electrode units to enter a first mode in which an AC signal is applied through its dielectric element; combining and controlling each of the grounding switches and each of the bidirectional switching switches of the electric field generator to enable each of the electrode units to enter a second mode in which the temperature is detected by its temperature sensor to obtain the temperature of each of the electrode units; comparing the temperature of each of the electrode units with a preset temperature threshold, and determining the working state of each of the electrode units based on the comparison result. 19. The method according to claim 17, characterized in that: the electric field generator is configured to: when the temperature of each of the electrode units of the electrode sheet is much lower than the preset temperature threshold, control the dual-purpose signal line to transmit an AC signal with an increased or unchanged voltage or current amplitude to the dielectric element of each of the electrode units. 20. The method according to claim 17, wherein the electric field generator is configured to: when there are electrode units on the electrode plate that are below but close to the preset temperature threshold, control the dual-purpose signal line to transmit the AC signal with reduced voltage or current amplitude to each of the electrode units. 21. The method according to claim 17, wherein the electric field generator is configured to: when there are electrode units on the electrode plate that are above the preset temperature threshold, control the dual-purpose signal line to stop transmitting the AC signal to each of the electrode units. 22. The method according to claim 17, wherein the electric field generator is configured to: when there are electrode units on the electrode plate that are above the preset temperature threshold, combine control of each of the grounding switches and each of the bidirectional switching switches to stop each of the dual-purpose signal lines from transmitting the AC signal to each of the electrode units.Alternatively, the dual-purpose signal line corresponding to the column group where the temperature detection signal exceeds the preset temperature threshold is located may stop transmitting AC signals, while the remaining dual-purpose signal lines may transmit AC signals. Claims 3 / 3 Page 4 CN 121288197 A Electric field generator, tumor electric field therapy system, electrode temperature detection method and electrode overheat detection method

[0001] This application is a divisional application of the invention patent application filed by the applicant on October 25, 2024, with application number 202411498459.9, entitled "Tumor Electric Field Therapy System and Temperature Detection Method, Signal Control Method". Technical Field

[0002] This application relates to tumor electric field therapy (TTF) technology, and more particularly to an electric field generator, a tumor electric field therapy system, an electrode temperature detection method and an electrode overheat detection method. Background Art

[0003] Tumor electric field therapy is a treatment method that uses a low-intensity, medium-to-high-frequency alternating electric field to prevent the formation of spindle microtubules during mitosis in certain tumor cells, thereby inhibiting the separation of intracellular organelles during cell division and inducing apoptosis during mitosis.

[0004] Compared with traditional cancer treatments, TTF has an innovative mechanism of action. Some physiological characteristics of tumor cells, such as their geometry and high-frequency mitosis, make them susceptible to the effects of TTF. TTF disrupts the normal aggregation of tubulin by applying directional forces to polar particles (such as macromolecules and organelles) within the cell. These processes may lead to physical damage to the cell membrane and apoptosis. At the end of mitosis, the morphology of the cleavage groove leads to an uneven distribution of the electric field around it. Under the influence of TTF, the electric field strength at the cleavage groove is significantly enhanced, and charged substances in the cell move towards the cleavage groove, interfering with or even destroying the formation of cell structures, ultimately leading to cell division failure and apoptosis.

[0005] Existing tumor electric field therapy systems use an electric field generator to transmit an alternating current signal for tumor electric field therapy to electrode pads, which then apply an alternating electric field to the tumor site for tumor electric field therapy. When the tumor treatment electric field is applied to the patient's body, heat accumulates at the electrode pad application site, and the temperature at the electrode pad application site also rises accordingly. Therefore, it is necessary to monitor the temperature at the electrode pad application site in real time. When the monitored temperature rises to a certain preset value, the electric field strength applied to the tumor site needs to be adjusted in time to avoid excessively high temperatures at the electrode pad application site, which could cause burns to the patient's skin.

[0006] The tumor electric field therapy system includes at least one pair of electrode pads, and each electrode pad contains multiple electrode units. Even if the same alternating current signal is applied to each electrode unit, the heat generated on each electrode unit will vary depending on its specific characteristics.The temperature varies depending on the location, meaning that the temperature of each electrode unit on the entire electrode sheet will not be completely uniform. This could result in some electrode units exceeding the preset temperature while others remain at a normal temperature. To avoid excessively high patient surface temperature during prolonged tumor electric field therapy and to ensure that an alternating electric field can be applied to the tumor site for an extended period, it is necessary to individually control the overheating electrode units. However, for existing electrode sheets, individual control of electrode units requires setting a conductive trace for each electrode unit in the electrode sheet substrate. This increases the number of conductive traces in the electrode sheet substrate, making the electrode sheet difficult to bend, and also thickens the cables electrically connected to the electrode sheet, increasing the overall weight of the electrode sheet and hindering its application.

[0007] Therefore, it is necessary to provide an electric field generator, a tumor electric field therapy system, an electrode sheet temperature detection method, and an electrode sheet overheat detection method that use fewer conductive traces to control multiple electrode units in a zoned manner. Specification 1 / 41 pages 5 CN 121288197 A Summary of the Invention

[0008] The first objective of this application is to provide an electric field generator to solve or eliminate problems in related technologies.

[0009] The second objective of this application is to provide a tumor electric field therapy system.

[0010] The third objective of this application is to provide an electrode temperature detection method.

[0011] The fourth objective of this application is to provide an electrode overheat detection method.

[0012] To achieve the above objectives, a first aspect of this application provides an electric field generator for providing alternating current signals to electrode pads in a tumor electric field therapy system. The electrode pads include a flexible circuit board with multiple grounding lines and multiple dual-purpose signal lines, and multiple electrode units disposed on the flexible circuit board. Each electrode unit has a dielectric element for applying the alternating current signal and a temperature sensor for detecting temperature, having a ground terminal and a signal terminal. The signal terminal of the temperature sensor in each electrode unit is short-circuited to its dielectric element. The multiple electrode units are circuitically configured into multiple row groups and multiple column groups, with each electrode unit located in the same row group... The grounding terminals of the temperature sensors in the electrode units are all short-circuited through the same grounding wire. The grounding terminals of the temperature sensors in each electrode unit located in different rows are connected in parallel through different grounding wires. The signal terminals of the dielectric elements and temperature sensors in each electrode unit located in the same column are all short-circuited through the same dual-purpose signal line. The signal terminals of the dielectric elements and temperature sensors in each electrode unit located in different columns are connected in parallel through different dual-purpose signal lines. The electric field generator is equipped with multiple grounding switches and multiple bidirectional switching switches corresponding to the electrode plates.Each grounding wire of the electrode sheet is grounded through a corresponding grounding switch, and each dual-purpose signal line is electrically connected to a corresponding bidirectional switching switch. Each dual-purpose signal line switches between receiving an AC signal in a first mode and receiving a DC signal in a second mode via the bidirectional switching switch connected in series with it. In the first mode, the electrode unit applies an AC signal through its dielectric element, and in the second mode, it detects the temperature through its temperature sensor.

[0013] The electric field generator according to the first aspect of this application controls the grounding switches electrically connected to each grounding wire of the electrode sheet and the bidirectional switching switches electrically connected to each dual-purpose signal line of the electrode sheet to switch between transmitting AC signals to the dielectric element of each electrode unit and transmitting DC signals to the temperature sensor of each electrode unit to collect temperature via each dual-purpose signal line. This achieves zoned control and comprehensive temperature monitoring of each electrode unit of the electrode sheet using fewer conductive traces and facilitates electrode sheet application.

[0014] To achieve the above objectives, a second aspect of this application provides a tumor electric field therapy system, comprising: an electrode sheet, the electrode sheet including a flexible circuit board having multiple grounding lines and multiple dual-purpose signal lines therein, and multiple electrode units disposed on the flexible circuit board, each electrode unit having a dielectric element for applying an alternating current signal and a temperature sensor for detecting temperature having a ground terminal and a signal terminal, wherein the signal terminal of the temperature sensor of the electrode unit is short-circuited to its dielectric element; the multiple electrode units are configured in the circuit as multiple row groups and multiple column groups, the ground terminals of the temperature sensors of each electrode unit located in the same row group are all short-circuited through the same grounding line, the ground terminals of the temperature sensors of each electrode unit located in different row groups are respectively connected in parallel through different grounding lines, the dielectric element and the signal terminal of the temperature sensor of each electrode unit located in the same column group are all short-circuited through the same dual-purpose signal line, the dielectric element and the signal terminal of the temperature sensor of each electrode unit located in different column groups are respectively connected in parallel through different dual-purpose signal lines; and the aforementioned electric field generator.

[0015] To achieve the above objectives, a third aspect of this application provides an electrode temperature detection method, applied to the electric field generator described on page 2 / 41 of the previous specification (CN 121288197 A) or the aforementioned tumor electric field therapy system. The method includes: controlling each of the bidirectional switching switches of the electric field generator to disconnect the alternating current signal applied to the dielectric element of each of the electrode units, while simultaneously connecting the direct current signal applied to the signal terminal of the temperature sensor of each of the electrode units; and sequentially and individually turning on each of the grounding switches of the electric field generator to obtain the temperature detection signal of the temperature sensor of each of the electrode units.

[0016] To achieve the above objectives, a fourth aspect of this application provides an electrode temperature detection method, applied to the aforementioned electric field generator or the aforementioned tumor electric field therapy system. The method includes: combining and controlling each of the grounding switches and each of the bidirectional switching switches of the electric field generator to enable each of the electrode units to enter a first mode in which an AC signal is applied through its dielectric element; combining and controlling each of the grounding switches and each of the bidirectional switching switches of the electric field generator to enable each of the electrode units to enter a second mode in which temperature is detected or collected through its sensor to obtain the temperature of each of the electrode units; comparing the temperature of each of the electrode units with a preset temperature threshold, and determining the working state of each of the electrode units based on the comparison result.

[0017] The above description is only an overview of the technical solution of this application. In order to better understand the technical means of this application and to implement it according to the contents of the specification, and to make the above and other objects, features and advantages of this application more obvious and understandable, specific embodiments of this application are described below.

[0018] FIG1 is a schematic diagram of a framework of a tumor electric field therapy system according to an embodiment of the present application, showing a schematic diagram of the structure of the electrode sheet of the first embodiment;

[0019] FIG2 is a schematic diagram of a modified embodiment of the electrode sheet of the first embodiment of the tumor electric field therapy system shown in FIG1 of the present application;

[0020] FIG3 is a schematic diagram of the circuit connection of the tumor electric field system shown in FIG1 of the present application, showing a schematic diagram of the circuit connection between the electrode sheet of the first embodiment shown in FIG1 or the electrode sheet of the modified embodiment shown in FIG2 and the adapter shown in FIG1 of the first embodiment;

[0021] FIG4 is a schematic block diagram of the internal structure of the adapter shown in FIG3 of the present application;

[0022] FIG5 is a schematic block diagram of the internal structure of the electric field generator of the tumor electric field therapy system shown in FIG1 of the present application;

[0023] FIG6 is similar to FIG3, and is a schematic diagram of the circuit connection of a tumor electric field therapy system according to a second embodiment of the present application, showing a schematic diagram of the circuit connection between the electrode sheet of the second embodiment of the tumor electric field therapy system and the adapter shown in FIG3;

[0024] Figure 7, similar to Figure 3, is a circuit connection diagram of the tumor electric field therapy system according to the third embodiment of this application, showing the circuit connection diagram between the electrode sheet of the third embodiment of the tumor electric field therapy system and the adapter shown in Figure 3;

[0025] Figure 8, similar to Figure 3, is a circuit connection diagram of the tumor electric field therapy system according to the fourth embodiment of this application, showing the circuit connection diagram between the electrode sheet of the fourth embodiment of the tumor electric field therapy system and the adapter shown in Figure 3;

[0026] Figure 9, similar to Figure 1, is a frame diagram of the tumor electric field therapy system according to the fifth embodiment of this application, showing the structural diagram of the electrode sheet of the fifth embodiment;

[0027] Figure 10, similar to Figure 3, is a circuit connection diagram of the tumor electric field therapy system shown in Figure 9, illustrating the circuit connection between the electrode plate of the fifth embodiment shown in Figure 9 and the adapter shown in Figure 3;

[0028] Figure 11, similar to Figure 10, is a circuit connection diagram of the tumor electric field therapy system of the sixth embodiment of this application, illustrating another circuit connection between the electrode plate of the fifth embodiment shown in Figure 9 and the adapter shown in Figure 3;

[0029] Figure 12, similar to Figure 11, is a circuit connection diagram of the tumor electric field therapy system of the seventh embodiment of this application, illustrating yet another circuit connection between the electrode plate of the fifth embodiment shown in Figure 9 and the adapter shown in Figure 3;

[0030] Figure 13, similar to Figure 11, is a circuit connection diagram of the tumor electric field therapy system of the eighth embodiment of this application, illustrating yet another circuit connection between the electrode plate of the fifth embodiment shown in Figure 9 and the adapter shown in Figure 3;

[0031] Figure 14, similar to Figure 1, is a schematic diagram of the framework of the tumor electric field therapy system according to the ninth embodiment of this application, showing a schematic diagram of the structure of the electrode sheet of the ninth embodiment;

[0032] Figure 15 is a schematic diagram of the circuit connection of the tumor electric field therapy system shown in Figure 14, showing a schematic diagram of the circuit connection between the electrode sheet of the ninth embodiment shown in Figure 14 and the adapter shown in Figure 3;

[0033] Figure 16, similar to Figure 15, is a schematic diagram of the circuit connection of the tumor electric field therapy system according to the tenth embodiment of this application, showing another schematic diagram of the circuit connection between the electrode sheet of the ninth embodiment shown in Figure 14 and the adapter shown in Figure 3;

[0034] Figure 17 is a flowchart of a temperature detection method for a tumor electric field therapy system according to an embodiment of this application;

[0035] Figure 18 is a flowchart of an AC signal application control method for tumor electric field therapy according to an embodiment of this application;

[0036] Figure 19 is a flowchart of a signal control method for tumor electric field therapy according to an embodiment of this application;

[0037] Figure 20 is a flowchart of an electrode sheet temperature detection method according to another embodiment of this application;

[0038] Figure 21 is a flowchart illustrating an alternating current signal application method for tumor electric field therapy according to another embodiment of this application;

[0039] Figure 22 is a flowchart illustrating an alternating current signal application method based on temperature detection signal according to an embodiment of this application;

[0040] Figure 23 is a flowchart illustrating an alternating current signal application method based on temperature detection signal according to another embodiment of this application.

[0041] Explanation of reference numerals:

[0042] Tumor electric field therapy system 100, electrode sheets 10, 10A, 10B, 10C, 10D, 10E, 10F, 10G, 10H, 10J, flexibleCircuit boards 11, 11A, 11B, 11C, 11D, 11E, 11F, 11G, 11H, 11J; connector 111; wiring part 112; bridging part 113; electrode unit 12; first cable 13; temperature sensor 14; grounding terminal 14-1; signal terminal 14-2; dielectric element 15; diode 16; grounding wire 18; first grounding wire 18-1; second grounding wire 18-2; third grounding wire 18-3; fourth grounding wire 18-4; dual-purpose signal line 19; first dual-purpose signal line 19-1; second dual-purpose signal line 19-2; third dual-purpose signal line 19-3; fourth dual-purpose signal line 19- 4. Fifth dual-purpose signal line 19-5, adapter 20, second cable 21, first controller 22, analog-to-digital converter 23, voltage divider resistor 24, grounding switch 25, first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, fourth grounding switch 25-4, bidirectional switch 26, first bidirectional switch 26-1, second bidirectional switch 26-2, third bidirectional switch 26-3, fourth bidirectional switch 26-4, fifth bidirectional switch 26-5, first communication unit 27, AC signal line 28, first power module 29, electric field generator 30, second power module 31, second controller 32, second communication unit 33, AC signal generator 34, AC signal switch 35, first connector 40, first plug 41, first socket 42, second connector 50, second plug 51, second socket 52. Detailed Embodiments

[0043] The embodiments of the technical solution of this application will be described in detail below with reference to the accompanying drawings. The following embodiments are only used to more clearly illustrate the technical solutions of this application, and are therefore only examples, and should not be used to limit the scope of protection of this application.

[0044] FIG1 is a schematic diagram of a tumor electric field therapy system 100 according to an embodiment of this application. As shown in FIG1, the tumor electric field therapy system 100 includes: at least one pair of electrode plates 10, an adapter 20 electrically connected to the electrode plates 10, and an electric field generator 30 electrically connected to the adapter 20. The electric field generator 30 generates an alternating current signal for tumor treatment and applies the alternating current signal to the electrode plates 10 through the adapter 20 to generate an alternating current signal on the paired electrode plates 10. The adapter 20 is electrically connected between the electrode plates 10 and the electric field generator 30 for transmitting the alternating current signal generated by the electric field generator 30 to the electrode plates 10. In other words, the electric field generator 30 can generate an alternating current signal, which is transmitted to each electrode 10 through the adapter 20, thereby generating a therapeutic electric field for treating tumors between the same pair of electrode 10.

[0045] As shown in FIG1, in this embodiment, the number of electrode 10 is 4. From the spatial arrangement, each electrode 10Each electrode unit 10 includes multiple electrode units 12 arranged in both axially symmetrical and centrally symmetrical configurations, a number of connecting portions 111 located between adjacent electrode units 12, a bridging portion 113 spanning between adjacent connecting portions 111, a wiring portion 112 connected to the bridging portion 113, and a first cable 13 connected to the wiring portion 112. The bridging portion 113 and the wiring portion 112 are arranged perpendicularly to each other, forming a "T" shape. The bridging portion 113 is spanned between adjacent connecting portions 111. Each electrode unit 12 of the electrode sheet 10 is electrically connected to the adapter 20 via the first cable 13.

[0046] Each electrode unit 12 has a temperature sensor 14 and a dielectric element 15. The temperature sensor 14 is used to detect the temperature of the electrode unit 12 applied to the patient's body surface. It can be a thermistor element or a temperature sensor other than a thermistor, and can be set at any position on the electrode unit 12. The dielectric element 15 is used to apply an alternating current signal to the tumor site of the patient. The dielectric element 15 can be a dielectric ceramic sheet or a polymer dielectric layer made of polymer material. In this embodiment, each dielectric element 15 has a through hole (not labeled) in the middle for accommodating a corresponding temperature sensor 14. Each electrode unit 12 may also include a diode 16 connected in series with the temperature sensor 14 to prevent reverse current flow and prevent detection signals from other electrode units 12 from affecting the temperature sensor 14. The ground terminal 14-1 of the temperature sensor 14 is connected in series with the anode of the diode 16 and grounded through the cathode of the diode 16.

[0047] In the first mode, the electrode unit 12 applies an alternating current signal through the dielectric element 15; in the second mode, the temperature of the patient's body surface to which the corresponding electrode unit 12 is attached is detected or acquired through the temperature sensor 14; in the third mode, the application of the alternating current signal is stopped and temperature detection and acquisition are stopped. The first mode, the second mode, and the third mode do not overlap in time. That is, the time period during which the dielectric element 15 of the electrode unit 12 applies an AC signal is staggered and does not overlap with the time period during which the temperature sensor 14 detects the temperature. The electrode unit 12 can cycle between applying an AC signal through its dielectric element 15 and detecting the temperature through its temperature sensor 14, that is, the electrode unit 12 can cycle between the first mode and the second mode. The electrode unit 12 can also cycle between the first mode, the second mode, and the third mode, that is, the electrode unit 12 cycles between applying an AC signal through the dielectric element 15, collecting or detecting the temperature through the temperature sensor 14, stopping the application of the AC signal, and collecting the temperature.

[0048] Each electrode sheet 10 includes an electrode array (not labeled) composed of 20 electrode units 12. Electrode array (not labeled)The circuit board 11 (notation) also includes a connecting part 111, a wiring part 112, and a bridging part 113. The 20 electrode units 12 are distributed in a spaced manner in an electrode array (notation) arranged in four rows and six columns. Specifically, the first and last rows each have four electrode units 12, the middle two rows each have six electrode units 12, the four electrode units 12 in the first row are located in the second to fifth columns, the six electrode units 12 in each of the middle two rows are located in the first to sixth columns, and the four electrode units 12 in the last row are also located in the second to fifth columns.

[0049] The connecting portion 111 is located only between two adjacent electrode units 12 arranged in the column direction in each of the third and fourth columns, and between two adjacent electrode units 12 arranged in the row direction in each row, except for the two electrode units 12 located in the third and fourth columns of each row. That is, the two adjacent electrode units 12 located in the third and fourth columns are only connected by the connecting portion 111 in the column direction, and are disconnected and not connected by the connecting portion 111 in the row direction; the electrode units 12 located in each of the first, second, fifth, and sixth columns are only connected by the connecting portion 111 arranged in the horizontal direction and the electrode units 12 adjacent to them in the row direction, and are disconnected in the column direction and between them and the adjacent electrode units 12. In other words, the two adjacent electrode units 12 located in the column direction in each of the first, second, fifth, and sixth columns are disconnected.

[0050] The electrode units 12 in the third column and the connecting portions 111 arranged longitudinally between the electrode units 12 in that column, as well as the electrode units 12 in the fourth column and the connecting portions 111 arranged longitudinally between the electrode units 12 in that column, all constitute the main trunk 114 of the electrode array (unlabeled). The connecting portions 111 located on opposite sides of the electrode units 12 in the third and fourth columns and connected to each electrode unit 12 in the third and fourth columns respectively by the connecting portions 111 arranged laterally, and the electrode units 12 connected to the connecting portions 111 arranged laterally, all constitute the branches 115 of the electrode array (unlabeled). That is, in this embodiment, the electrode array (unlabeled) includes two main trunks 114 and several branches 115 that extend laterally from the two main trunks 114 respectively. Each branch 115 has a free end away from the main trunk 114, and the free ends of adjacent branches 115 are disconnected. The position and distance between adjacent branches 115 can be freely adjusted according to the actual usage scenario. Specifically, one main branch 114 is composed of each electrode unit 12 located in the third column and a connecting portion 111 located between adjacent electrode units 12 in that column and arranged longitudinally; the other main branch 114 is composed of each electrode unit 12 located in the fourth column and a connecting portion 111 located between adjacent electrode units 12 in that column.The electrode units 12 are connected by a longitudinally arranged connecting portion 111. The remaining electrode units 12 connected to the main stem 114 via the laterally arranged connecting portions 111 are branches 115.

[0051] Specifically, the branches 115 are: a connecting portion 111 extending laterally to the left from the electrode unit 12 in the first row of the third column and located in the first row, and an electrode unit 12 connected to this connecting portion 111 and located in the second column of the first row; two connecting portions 111 extending laterally to the left from the electrode unit 12 in the second row of the third column and located in the second row, and two electrode units 12 located in the first column and second column of the second row; two connecting portions 111 extending laterally to the left from the electrode unit 12 in the third row and located in the third row, and two electrode units 12 located in the first column and second column of the third row; a connecting portion 111 extending laterally to the left from the electrode unit 12 in the fourth row and located in the fourth row, and a connecting portion 111 located in the second column and second column of the third row; and a connecting portion 111 extending laterally to the left from the electrode unit 12 in the third column and located in the fourth row, and a connecting portion 111 located in the second column and second column of the third row. Electrode unit 12 in the second column of the fourth row; a connecting portion 111 extending laterally to the right from the electrode unit 12 in the first row of the fourth row and located in the first row and an electrode unit 12 in the fifth column of the first row; two connecting portions 111 extending laterally to the right from the electrode unit 12 in the second row of the fourth row and located in the second row and two electrode units 12 located in the fifth and sixth columns of the second row; two connecting portions 111 extending laterally to the right from the electrode unit 12 in the third row of the fourth row and located in the third row and two electrode units 12 located in the fifth and sixth columns of the third row; a connecting portion 111 extending laterally to the right from the electrode unit 12 in the fourth row of the fourth row and located in the fourth row and an electrode unit 12 located in the fifth column of the fourth row.

[0052] The electrode array (unlabelled) is divided into a symmetrical left portion including three columns on the left and a right portion including three columns on the right, and the left and right portions are connected only by a bridging portion 113. The left side consists of a main stem 114 located in the third column and several branches 115 extending to the left from the main stem 114. The right side consists of a main stem 114 located in the fourth column and several branches 115 extending to the right from the main stem 114. The two main stems 114 are connected by a bridging portion 113. Specifically, the two main stems 114 are electrically connected by a bridging portion 113 between the connecting portions 111 of the electrode units 12 in the second row of the third column and the connecting portions 111 of the electrode units 12 in the second row of the fourth column and the connecting portions 111 of the electrode units 12 in the third row of the fourth column. The connecting portions 111 of the electrode units 12 in the second row of the third column and the connecting portions 111 of the electrode units 12 in the second row of the third column and the connecting portions 111 of the electrode units 12 in the second row of the fourth column and the connecting portions 113 are generally arranged in an "H" shape. In other embodiments, the bridging part 113 may also be located on page 6 / 41 of the specification (10 CN).121288197 A is located between an electrode unit 12 in the third column and an electrode unit 12 in the fourth column. Optionally, a bridging part 113 is erected between two electrode units 12 located in the third and fourth columns and adjacent in the row direction.

[0053] Each electrode unit 12 can be divided into peripheral electrode units 12 and central electrode units 12 according to its position in the electrode array (unlabeled). The peripheral electrode units 12 include four electrode units 12 located in the first row, two electrode units 12 located at opposite ends of the second row, two electrode units 12 located at opposite ends of the third row, and four electrode units 12 located in the fourth row. The central electrode units 12 include four electrode units 12 located in the middle of the second row and four electrode units 12 located in the middle of the third row. Among the multiple peripheral electrode units 12, some adjacent electrode units 12 are connected by a horizontally arranged connecting part 111, and some adjacent electrode units 12 are disconnected. Among the multiple electrode units 12 located on the periphery, adjacent electrode units 12 connected by connecting portions 111 are partially row-adjacent electrode units 12. Specifically, among the multiple electrode units 12 located on the periphery, electrode units 12 that are adjacent in column direction or diagonally adjacent are all disconnected; electrode units 12 that are partially row-adjacent are also disconnected; only electrode units 12 that are partially row-adjacent are connected by laterally extending connecting portions 111. Among the multiple electrode units 12 located in the center, only electrode units 12 that are adjacent in column direction on the main branch 114 are connected by longitudinally arranged connecting portions 111, and only electrode units 12 that are adjacent in row direction on the branch 115 are connected by laterally arranged connecting portions 111.

[0054] The electrode array (unlabeled) also has gaps (unlabeled) formed between a plurality of spaced electrode units 12, which allow moisture from the patient's skin to escape, heat exchange between the patient's skin and the outside world, or free breathing of the patient's skin. It also allows for free adjustment of the position and spacing between the branches 115, and avoids wrinkling when the electrode pads 10 are applied. The gaps (unlabeled) include a first gap D1 located between the two main branches 114 and a second gap D2 located between the branches 115. The first gap D1 is located between the third and fourth columns of electrode units 12, while the second gap D2 is located between adjacent rows of electrode units 12. That is, moving upwards along the row, the electrode unit 12 in the third column is disconnected from the adjacent electrode unit 12 in the fourth column, without a connecting part 111, forming the aforementioned first interval D1; and moving upwards along the column, only the two adjacent electrode units 12 in the third and fourth columns are connected by the connecting part 111, while the two adjacent electrode units 12 in the other four columns are not connected by the connecting part 111, forming the aforementioned second interval D2. The arrangement of the first and second intervals D1 and D2 is also possible.To increase the degree of freedom of some electrode units 12, wrinkles can also be avoided when attaching the electrode pads 10.

[0055] In some other embodiments, the tumor electric field therapy system 100 may have more or fewer electrode pads 10. In some other embodiments, each pair of electrode pads 10 has the same number of electrode units 12, and different pairs of electrode pads 10 may have different numbers of electrode units 12. In some other embodiments, 20 electrode units 12 may also be arranged in other ways. Of course, in some other embodiments, the electrode pads 10 may also have other numbers of electrode units 12. In summary, the implementation of this application is not limited by the number and arrangement of the electrode units 12 of the electrode pads 10.

[0056] The electrode sheet 10' shown in FIG2 is a variation of the electrode sheet 10 shown in FIG1. ​​The spatial structure of the electrode sheet 10' is the same as that of the electrode sheet 10, and it also includes a plurality of electrode units 12' arranged at intervals, a plurality of connecting portions 111' located between two adjacent electrode units 12', a wiring portion 112' connected to the bridging portion 113', a first cable 13' connected to the wiring portion 112', a first interval D1 formed between the third column electrode units 12' and the fourth column electrode units 12', and a second interval D2' formed between the electrode units 12' in adjacent rows. The only difference is that: the two adjacent electrode units 12' in the fourth column are arranged in a disconnected manner and are not connected by the vertically arranged connecting portions 111', but the two adjacent electrode units 12' in the fifth column are connected by the vertically arranged connecting portions 111'. The electrode unit 12' located in the fifth column and adjacent to the electrode unit 12' is connected by a horizontally arranged connecting part 111'; and the bridging part 113' connects the two electrode units 12' located in the third row and third column and the two electrode units 12' located in the third row and fourth column.

[0057] FIG3 is a schematic diagram of a circuit connection between the electrode sheet 10' of the first embodiment or a variation thereof shown in FIG1 for the tumor electric field therapy system 100, page 7 / 41 of the specification 11 CN 121288197 A and the adapter 20. It is worth noting that the arrangement of the electrode units 12 shown in FIG3 is to more clearly show the electrical connection between an electrode sheet 10 and the adapter 20. The arrangement of the electrode units 12 shown in FIG3 does not represent the spatial arrangement of the electrode units 12. The circuit connection is described below using the electrode sheet 10 in the first embodiment as an example. Referring to FIG1 and FIG3, the flexible circuit board 11 is embedded with multiple conductive traces, including multiple ground lines 18 and multiple dual-purpose signal lines 19. The first cable 13 has multi-core conductors (not shown) that are electrically connected one-to-one with the multiple grounding wires 18 and multiple dual-purpose signal lines 19 of the flexible circuit board 11. The flexible circuit board 11 is embedded with...The total number of grounding wires 18 and dual-purpose signal lines 19 does not exceed 10. Therefore, the number of wires in the first cable 13 does not exceed 10.

[0058] In this embodiment, each electrode sheet 10 is provided with 20 electrode units 12. The 20 electrode units 12 are arranged in the order of 1 to 20 in the circuit connection and are divided into four row groups and five column groups, that is, the 20 electrode units 12 are arranged in four rows and five columns in the circuit connection. The temperature sensor 14 in each electrode unit 12 includes a ground terminal 14-1 and a signal terminal 14-2. The dielectric element 15 and the temperature sensor 14 of each electrode unit 12 are soldered on the flexible circuit board 11, and each dielectric element 15 is short-circuited to the signal terminal 14-2 of the corresponding temperature sensor 14. Since the electrode units 12 are arranged in a four-row, five-column configuration in the circuit connection, and each electrode unit includes a corresponding dielectric element 15 and a corresponding temperature sensor 14, the multiple temperature sensors 14 are also arranged in a four-row, five-column configuration in the circuit connection, and the multiple dielectric elements 15 are also arranged in a four-row, five-column configuration in the circuit connection. It should be noted that this arrangement is for clearer illustration of the electrical connection between the electrode pads 10 and the adapter 20, and does not represent the spatial arrangement of the electrode units 12. The spatial structure may be a roughly array-like structure as shown in Figure 1, or it may be other structures, such as petal-shaped or scattering structures, and can be regular or irregular. The dielectric element 15 is configured to apply an alternating current signal to the patient's tumor site. The temperature sensor 14 is configured to detect the temperature of the patient's body surface in contact with the electrode pads 10 and output a temperature detection signal to the adapter 20. In this embodiment, the multi-purpose signal lines 19 of the flexible circuit board 11 are respectively arranged in a one-to-one correspondence with multiple columns of the electrode units 12, and are configured to transmit the AC signal generated by the electric field generator 30 to the dielectric element 15 in each electrode unit 12 in the corresponding column. That is, the dielectric elements 15 located in the same column are all short-circuited through the same multi-purpose signal line 19 of the flexible circuit board 11, and the dielectric elements 15 located in different columns are respectively connected in parallel through different multi-purpose signal lines 19 of the flexible circuit board 11. The multi-purpose signal lines 19 of the flexible circuit board 11 are electrically connected to the corresponding wires in the first cable 13, and then electrically connected to the electric field generator 30 through the adapter 20. In other words, the multi-purpose signal lines 19 of the flexible circuit board 11 receive the AC signal generated by the electric field generator 30 through the first cable 13 and the adapter 20.

[0059] Multiple grounding lines 18 are respectively configured to correspond one-to-one with multiple rows of electrode units 12. The multiple grounding lines 18 are used to sequentially short-circuit and ground the temperature sensor 14 of each corresponding electrode unit 12 in each row group. That is, the grounding terminals 14-1 of multiple temperature sensors 14 located in the same row group are all short-circuited through the same grounding line 18 of the flexible circuit board 11.The grounding terminals 14-1 of the temperature sensors 14 in different rows are respectively connected to ground in parallel through different grounding lines 18 of the flexible circuit board 11. During the temperature detection period or in the second mode, only one of the multiple grounding lines 18 is conducting at any given time, while the others are disconnected.

[0060] Each of the multiple dual-purpose signal lines 19 is also configured to transmit a DC signal to the temperature sensor 14 in each electrode unit 12 in the corresponding column group to collect and transmit the detected temperature signal. The signal terminals 14-2 of the multiple temperature sensors 14 located in different columns are respectively connected in parallel through different dual-purpose signal lines 19 of the flexible circuit board 11, and the signal terminals 14-2 of the multiple temperature sensors 14 located in the same column group are all short-circuited to the same dual-purpose signal line 19 of the flexible circuit board 11. Specifically, each dual-purpose signal line 19 is configured to short-connect the signal terminal 14-2 of the temperature sensor 14 of at most one electrode unit 12 in each row group to an external device for receiving detection signals. The signal terminals 14-2 of the temperature sensor 14 connected to each of the multiple dual-purpose signal lines 19 are different to avoid subsequent output of duplicate signals as per the instructions for dual-purpose signal lines, page 8 / 41, CN 121288197 A 19. That is, when the number of electrode units 12 in a row group is the same as the number of dual-purpose signal lines 19, each dual-purpose signal line 19 is electrically connected to the signal terminal 14-2 of the temperature sensor 14 of a different electrode unit 12 in that row group; when the number of electrode units 12 in a row group is less than the number of dual-purpose signal lines 19, at least one dual-purpose signal line 19 is not electrically connected to the signal terminal 14-2 of the temperature sensor 14 of the electrode unit 12, and the remaining dual-purpose signal lines 19 are electrically connected to the signal terminal 14-2 of the temperature sensor 14 of a different electrode unit 12 in that row group. In this embodiment, the external device for receiving the detection signal is an adapter 20. The dual-purpose signal lines 19 of the flexible circuit board 11 receive DC signals from the adapter 20 or the electric field generator 30 through the first cable 13, and transmit the collected or detected temperature signals to the adapter 20, and then to the electric field generator 30 through the adapter 20.

[0061] In this embodiment, with a temperature sensor 14 configured in each electrode unit 12 for temperature detection, the above-described circuit design reduces the number of wires in the first cable 13, avoiding increased cable thickness and stiffness, which would increase the difficulty of cable fixation; simultaneously, it avoids the increased number of wires in the first cable 13 affecting the adhesion between the electrode sheet 10 and the corresponding body surface of the patient's tumor site. The flexible circuit board 11 has a total of 9 embedded grounding wires 18 and dual-purpose signal lines 19. Specifically, in this embodiment, the flexible circuit board 11 has 4 embedded grounding wires 18 and 5 embedded dual-purpose signal lines 19.

[0062] In the tumor electric field therapy system 100, the number of conductive lines electrically connected to the grounding wire 18 is related to the number of rows M of the electrode unit 12, which can be greater than or equal to the number of rows of the electrode unit 12, where M is a positive integer. In the tumor electric field therapy system 100, the number of conductive lines electrically connected to the dual-purpose signal line 19 is related to the number of columns N of the electrode unit 12, which can be greater than or equal to the number of columns of the electrode unit 12, where N is a positive integer. The number of lines L embedded in the flexible circuit board 11 of the electrode sheet 10 is equal to the sum of the number of grounding wires 18 and the number of dual-purpose signal lines 19. In this embodiment, the number of grounding wires 18 is equal to the number of rows M of the electrode unit 12; the number of dual-purpose signal lines 19 is equal to the number of columns N of the electrode unit 12.

[0063] In the embodiment shown in FIG3, specifically, the electrode sheet 10 of this embodiment includes 4 grounding wires 18, each grounding wire 18 being used to ground the grounding terminals 14-1 of the temperature sensors 14 in the same row group. The four grounding wires 18 of the electrode sheet 10 are the first grounding wire 18-1, the second grounding wire 18-2, the third grounding wire 18-3, and the fourth grounding wire 18-4. In the four rows of the electrode sheet 10, the first row includes electrode units 12-1 to 12-5, the second row includes electrode units 12-6 to 12-10, the third row includes electrode units 12-11 to 12-15, and the fourth row includes electrode units 12-16 to 12-20. Specifically, the first grounding wire 18-1 is used to ground electrode units 12-1 to 12-5 in the first row group; the second grounding wire 18-2 is used to ground electrode units 12-6 to 12-10 in the second row group; the third grounding wire 18-3 is used to ground electrode units 12-11 to 12-15 in the third row group; and the fourth grounding wire 18-4 is used to ground electrode units 12-16 to 12-20 in the fourth row group. It should be noted that these grounding wires 18 can be selectively closed or opened, which can be achieved by connecting each grounding wire 18 in series with a grounding switch, as will be described in detail below. The phrase "grounding electrode unit 12" can refer to grounding the grounding terminal 14-1 of the temperature sensor 14 in electrode unit 12, or it can refer to the diode 16 being connected in series with the temperature sensor 14 in the same electrode unit 12 and grounded together. In short, each grounding wire 18 short-circuits and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in each row group.

[0064] Continuing to refer to FIG3, the electrode sheet 10 of this embodiment also includes five dual-purpose signal lines 19. One end of each dual-purpose signal line 19 is connected to all electrode units 12 in each column group, and the other end is connected to an adapter 20 for receiving temperature detection signals and transmitting AC signals. That is, for each row group, each dual-purpose signal line 19 canSelecting to connect one of the electrode units 12 or not connecting any of the electrode units 12 in the row group avoids subsequent repetitive signal output from the dual-purpose signal line 19. Specifically, the five dual-purpose signal lines 19 of the electrode sheet 10 include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. (See specification 9 / 41 page 13 CN 121288197 A). One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the four electrode units 12 (electrode units 12-1, 12-6, 12-11, and 12-16) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the electrode units 12-2, 12-7, 12-8-9-10, 12-1 ... 12. Each of the four electrode units 12 (12-17) has its own dielectric element 15 and its own temperature sensor 14 signal terminal 14-2. One end of the third dual-purpose signal line 19-3 is connected to the dielectric element 15 and its own temperature sensor 14 signal terminal 14-2 of each of the four electrode units 12 (12-3, 12-8, 12-13, 12-18). One end of the fourth dual-purpose signal line 19-4 is connected to the dielectric element 15 and its own temperature sensor 14 signal terminal 14-2 of each of the four electrode units 12 (12-4, 12-9, 12-14, 12-19). One end of the fifth dual-purpose signal line 19-5 is connected to the dielectric element 15 and its own temperature sensor 14 signal terminal 14-2 of each of the four electrode units 12 (12-5, 12-10, 12-15, 12-20). In short, each dual-purpose signal line 19 short-circuits the signal terminals 14-2 of each dielectric element 15 and each temperature sensor 14 of each electrode unit 12 located in the same column group and connects them in parallel for connection to external devices. It should be noted that these dual-purpose signal lines 19 can selectively transmit AC signals or receive temperature detection signals. This can be achieved by connecting each dual-purpose signal line 19 in series with a bidirectional switching switch 26 and cooperating with the closing or opening of the grounding wire 18, which will be described in detail below.

[0065] The multiple grounding wires 18 and the multiple dual-purpose signal lines 19 are all conductive traces embedded in the flexible circuit board 11. The flexible circuit board 11 is electrically connected to the first cable 13. The multiple grounding wires 18 and the multiple dual-purpose signal lines 19 embedded in the flexible circuit board 11 are electrically connected to the corresponding wires (not shown) in the first cable 13.

[0066] The tumor electric field therapy system 100 of this embodiment includes at least one pair of the above-mentioned electrode plates 10, and the electrode plates 10 are electrically connected to each other.An adapter 20 is electrically connected to the electrode plate 10, and an electric field generator 30 is electrically connected to the adapter 20. The adapter 20 is connected between the electrode plate 10 and the electric field generator 30. The electric field generator 30 provides AC or DC signals to the dielectric elements 15 in the plurality of electrode units 12 of the electrode plate 10 via the adapter 20 and the dual-purpose signal line 19 of the electrode plate 10, and is used to receive temperature detection signals output by the temperature sensors 14 in the plurality of electrode units 12. The adapter 20 is configured to transmit the AC signal generated by the electric field generator 30 to the dual-purpose signal line 19 of the electrode plate 10, and is also configured to transmit DC signals to the dual-purpose signal line 19 of the electrode plate and receive temperature detection signals output by the dual-purpose signal line 19 of the electrode plate 10.

[0067] Referring to Figures 3 and 4, the adapter 20 includes: a first controller 22, multiple sets of analog-to-digital converters 23 connected to the first controller 22, multiple sets of voltage-reducing resistors 24 corresponding to the multiple sets of analog-to-digital converters 23, multiple sets of grounding switches 25 and multiple sets of bidirectional switching switches 26, a first communication unit 27, multiple AC signal lines 28 respectively connected to the multiple sets of bidirectional switching switches 26, and a first power module 29 connected to the first communication unit 27, the first controller 22 and the multiple sets of analog-to-digital converters 23. The first power module 29 provides DC power VCC to each electronic component of the adapter 20. The adapter 20 also includes multiple circuit lines (unlabeled). Taking the electrical connection between a single electrode plate 10 and the adapter 20 as an example, the multiple circuit lines (unlabeled) are electrically connected to the multiple grounding lines 18 and multiple dual-purpose signal lines 19 in the flexible circuit board 11 of the corresponding electrode plate 10 through the first cable 13 of the corresponding electrode plate 10. The multiple circuit lines (unlabeled) include multiple AC signal lines 28 that transmit AC signals to the corresponding electrode 10 and are electrically connected to the multiple dual-purpose signal lines 19 in the flexible circuit board 11 of the corresponding electrode 10; multiple circuit lines (unlabeled) that are electrically connected one-to-one to the multiple dual-purpose signal lines 19 in the flexible circuit board 11 of the corresponding electrode 10 and are used to power each temperature sensor 14 of the electrode 10 or transmit the temperature detection signal of the electrode 10; and multiple circuit lines (unlabeled) that are electrically connected one-to-one to the multiple grounding lines 18 in the flexible circuit board 11 of the corresponding electrode 10. The number P of circuit lines electrically connecting adapter 20 to one electrode piece 10 is equal to the sum of the number of rows M and columns N of the electrode units 12 of electrode piece 10 plus 1; the number H of circuit lines electrically connecting adapter 20 to X electrode pieces 10 is equal to X times the number of circuit lines electrically connecting it to a single electrode piece 10, that is, H=XP=X×(M+N+1). The number of groups of grounding switches 25 and the number of groups of bidirectional switching switches 26 are both related to the number of electrode pieces 10. The number of groups of grounding switches 25 and the number of groups of bidirectional switching switches 26 are related to the number of electrode pieces 10.The number of groups of switching switches 26 is the same and not less than the number of electrode plates 10. Preferably, the number of groups of grounding switches 25 and bidirectional switching switches 26 is the same as the number of electrode plates 10. The following is a detailed description of the electrical connection between an electrode plate 10 with 20 electrode units 12 and the adapter 20.

[0068] Each group of grounding switches 25 is provided with multiple grounding switches 25. The multiple grounding switches 25 are respectively connected to the adapter 20 and electrically connected to the circuit lines (unlabeled) corresponding to the multiple grounding wires 18 of the corresponding electrode plate 10, and are configured to control the conduction or disconnection of the multiple grounding wires 18. The circuit lines (unlabeled) that are electrically connected to the multiple grounding wires 18 of the electrode plate 10 are grounded at the end near the grounding switch 25. The number of grounding switches 25 in each group of grounding switches 25 is related to the number of grounding wires 18 of the flexible circuit board 11 of the corresponding electrode plate 10. In this embodiment, the two are equal. As shown in Figure 3, in this embodiment, each group of grounding switches 25 is provided with multiple grounding switches 25, and in this embodiment there are four, namely the first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4. Each group of multiple grounding switches 25 controls the closing or opening of the corresponding grounding wire 18 of a corresponding electrode piece 10. Specifically, the first grounding switch 25-1 is used to control the closing or opening of the first grounding wire 18-1 of the corresponding electrode piece 10, and can then cooperate with the corresponding group of bidirectional switching switches 26 to control the energization and de-energization of the temperature sensors 14 of the five electrode units 12 from electrode unit 12-1 to electrode unit 12-5 in the first row of the electrode piece 10; the second grounding switch 25-2 is used to control the closing or opening of the second grounding wire 18-2 of the electrode piece 10, and can then cooperate with the corresponding group of bidirectional switching switches 26 to control the energization and de-energization of the electrode piece 10. The second row of electrode units 12 (12-6 to 12-10) controls the energization and de-energization of the temperature sensors 14 of each of the five electrode units 12. A third grounding switch 25-3 controls the opening and closing of the third grounding wire 18-3 of the electrode 10, and can cooperate with the corresponding bidirectional switching switch 26 to control the energization and de-energization of the temperature sensors 14 of each of the five electrode units 12 (12-11 to 12-15) in the third row of electrode units 10. A fourth grounding switch 25-4 controls the opening and closing of the fourth grounding wire 18-4 of the electrode 10, and can cooperate with the corresponding bidirectional switching switch 26 to control the energization and de-energization of the temperature sensors 14 of each of the five electrode units 12 (12-16 to 12-20) in the fourth row of electrode units 10. The grounding switches 25 can be mechanical switches, such as relays. The grounding switches 25 can also be electronic switches, and each grounding switch 25 can be opened and closed by the first controller 22 of the adapter 20.

[0069] In this embodiment, all sets of grounding switches 25 are electronic switches. The first controller 22 is communicatively connected to the multiple sets of grounding switches 25 and is used to sequentially and cyclically control the opening and closing states of multiple grounding switches 25 in each set of grounding switches 25, thereby sequentially and individually turning on each of the multiple grounding wires 18 of the corresponding electrode 10 and cooperating with the switching of the corresponding bidirectional switching switch 26, so as to sequentially and time-divisionally collect the temperature of the patient's body surface detected by all temperature sensors 14 on the electrode 10. The number of grounding switches 25 in each set is greater than or equal to the number of grounding wires 18 of the flexible circuit board 11 of the corresponding electrode 10. In this embodiment, the number of grounding switches 25 in each set is the same as the number of grounding wires 18 of the corresponding electrode 10.

[0070] Each set of bidirectional switching switches 26 is provided with multiple bidirectional switching switches 26, and the multiple bidirectional switching switches 26 in each set are respectively connected to the adapter 20 and electrically connected to the circuit lines (unlabeled) corresponding one-to-one with the multi-channel dual-purpose signal lines 19 of the corresponding electrode 10. The number of bidirectional switching switches 26 in each group is related to the number of dual-purpose signal lines 19 on the flexible circuit board 11 of the corresponding electrode sheet 10, and is greater than or equal to the number of dual-purpose signal lines 19 on the flexible circuit board 11 of the corresponding electrode sheet 10. In the embodiment shown in FIG3, the two are equal. Each bidirectional switching switch 26 has a acquisition terminal labeled 1 and an input terminal labeled 2. The acquisition terminals 1 of multiple bidirectional switching switches 26 in the same group are electrically connected to the corresponding detection channels in the multiple detection channels of the corresponding group of analog-to-digital converters 23, and the input terminals 2 of each bidirectional switching switch 26 in the same group are electrically connected to the corresponding AC signal line 28. Each bidirectional switching switch 26 is configured to control the multiple dual-purpose signal lines 19 to connect to the corresponding AC signal line 28 to transmit AC signals or to connect to the corresponding detection channel of the corresponding group of analog-to-digital converters 23 to receive the temperature detection signal output by the temperature sensor 14.

[0071] As shown in FIG3, taking the electrical connection of one electrode plate 10 with the adapter 20 as an example, in this embodiment with 20 electrode units 12, the multiple bidirectional switching switches 26 are respectively a first bidirectional switching switch 26-1, a second bidirectional switching switch 26-2, a third bidirectional switching switch 26-3, a fourth bidirectional switching switch 26-4, and a fifth bidirectional switching switch 26-5. The multiple bidirectional switching switches 26 in the same group each control the switching of a corresponding dual-purpose signal line 19 of the same electrode plate 10 between transmitting AC power signals and transmitting temperature detection signals. Specifically, the first bidirectional switching switch 26-1 is used to control the switching of the first dual-purpose signal line 19-1 of the corresponding electrode plate 10 between transmitting AC power signals and transmitting temperature detection signals, thereby...The control controls the switching between the conduction of the dielectric elements 15 of each electrode unit 12-1, electrode unit 12-6, electrode unit 12-11, and electrode unit 12-16 in the first column of the electrode sheet 10 and the conduction of the signal terminals 14-2 of each temperature sensor 14 in the first column of the electrode unit 12-1, electrode unit 12-6, electrode unit 12-11, and electrode unit 12-16, and coordinates with the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4, so that the first column of electrode units... Electrode units 12-1, 12-6, 12-11, and 12-16 transmit AC signals to the patient or output temperature detection signals collected by the temperature sensors 14 of the corresponding electrode units 12 to the corresponding analog-to-digital converter 23. A second bidirectional switch 26-2 controls the switching of the second dual-purpose signal line 19-2 of the corresponding electrode 10 between transmitting AC signals and transmitting temperature detection signals. This controls the switching between the conduction of the dielectric elements 15 of each electrode unit 12-2, 12-7, 12-12, and 12-17 in the second column of the electrode 10 and the conduction of the signal terminals 14-2 of each temperature sensor 14 in the second column of the electrode unit 12-2, 12-7, 12-12, and 12-17, and the corresponding first grounding switch 25-1, second grounding switch 25-2, and third grounding switch 25-3. The fourth grounding switch 25-4 is used to enable the second row of electrode units 12-2, 12-7, 12-12, and 12-17 to transmit AC signals to the patient or output temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23; the third bidirectional switching switch 26-3 is used to control the switching of the third dual-purpose signal line 19-3 of the corresponding electrode pad 10 between transmitting AC signals and transmitting temperature detection signals, thereby controlling the conduction of each dielectric element 15 of the electrode units 12-3, 12-8, 12-13, and 12-18 in the third row of electrode pads 10. The switching between the conduction of the signal terminals 14-2 of the temperature sensors 14 of the electrode units 12-3, 12-8, 12-13, and 12-18 in the third column group and the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4, enables the third column of electrode units 12-3, 12-8, 12-13, and 12-18 to transmit AC signals to the patient or output temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23; the fourth bidirectional switching switch 26-4 is used to control the phaseThe switching of the fourth dual-use signal line 19-4 of the electrode plate 10 between transmitting AC signals and transmitting temperature detection signals controls the conduction of each dielectric element 15 of the electrode units 12-4, 12-9, 12-14, and 12-19 in the fourth column of the electrode plate 10, and the conduction of the signal terminals 14-2 of each temperature sensor 14 in the fourth column of the electrode units 12-4, 12-9, 12-14, and 12-19. This switching is also controlled by the corresponding first grounding switch 25-1, second grounding switch 25-2, and third grounding switch 25-3. The three grounding switches 25-3 and 25-4 work together to enable the fourth column of electrode units 12-4, 12-9, 12-14, and 12-19 to transmit AC signals to the patient or output temperature detection signals collected by the temperature sensors 14 of the electrode units 12 to the corresponding analog-to-digital converter 23; the fifth bidirectional switching switch 26-5 is used to control the switching of the fifth dual-purpose signal line 19-5 of the corresponding electrode pad 10 between transmitting AC signals and transmitting temperature detection signals, thereby controlling the electrode units 12-5, 12-9, 12-14, and 12-19 in the fifth column of the electrode pad 10. 10. The switching between the conduction of each dielectric element 15 of electrode units 12-15 and electrode units 12-20 and the conduction of the signal terminals 14-2 of each temperature sensor 14 of electrode units 12-10, electrode units 12-15 and electrode units 12-20, and the switching between these two, and in conjunction with the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3 and fourth grounding switch 25-4, so that the fifth column of electrode units 12-5, electrode units 12-10, electrode units 12-15 and electrode units 12-20 transmits AC signals to the patient or outputs temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23. When the input terminal 2 of each bidirectional switching switch 26 is turned on and the acquisition terminal 1 is turned off, AC signals can be transmitted to the dielectric elements 15 of each electrode unit 12 of the corresponding electrode plate 10. When the acquisition terminal 1 of each bidirectional switching switch 26 is turned on and the input terminal 2 is turned off, it can cooperate with each grounding switch 25 in the corresponding group of grounding switches 25 to transmit the temperature detection signals collected by the temperature sensors 14 of each electrode unit 12 on the electrode plate 10 in a time-division manner. The bidirectional switching switch 26 can be a mechanical switch, such as a relay. The bidirectional switching switch 26 can also be an electronic switch, and the switching between the acquisition terminal 1 and the input terminal 2 of each bidirectional switching switch 26 can be controlled by the first controller 22 of the adapter 20.

[0072] In this embodiment, all of the multiple bidirectional switching switches 26 are electronic switches. The first controller 22 and the multiple bidirectional switchesThe switching switch 26 is a communication connection used to control the switching of multiple bidirectional switching switches 26 in each group between their respective acquisition terminals 1 and input terminals 2, and to cooperate with the closing or opening of the corresponding grounding switch 25, so as to continuously monitor the temperature of the patient's body surface detected by all temperature sensors 14 on the electrode pad 10 or to transmit AC signals to the patient.

[0073] In this embodiment, each group of analog-to-digital converters 23 is electrically connected to the acquisition terminals 1 of multiple bidirectional switching switches 26 in the corresponding group of bidirectional switching switches 26 through multiple circuit lines (unlabeled) in the adapter 20, and is configured to receive the temperature detection signal transmitted by the multi-channel dual-purpose signal line 19 of the corresponding electrode pad 10, and convert the temperature detection signal from analog signal to digital signal. Each group of analog-to-digital converters 23 includes multiple detection channels A, B, C, D, E, and each detection channel A, B, C, D, E is used to connect to one corresponding dual-purpose signal line 19 in the multi-channel dual-purpose signal line 19 through the corresponding bidirectional switching switch 26. The number of detection channels in each group of analog-to-digital converters 23 is related to the number of bidirectional switching switches 26 in the corresponding group. The number of detection channels in each group of analog-to-digital converters 23 is related to the number of column groups of electrode units 12 in the corresponding electrode sheet 10. Specifically, the number of detection channels in each group of analog-to-digital converters 23 is equal to the number of bidirectional switching switches 26 in the corresponding group of bidirectional switching switches 26, and is not less than the number of column groups of electrode units 12 in the corresponding electrode sheet 10. As shown in Figure 3, each group of analog-to-digital converters 23 contains a total of 5 detection channels A, B, C, D, and E, which are respectively the first detection channel A, the second detection channel B, the third detection channel C, the fourth detection channel D, and the fifth detection channel E. The first detection channel A is connected to the first dual-purpose signal line 19-1 via the acquisition terminal 1 of the first bidirectional switch 26-1; the second detection channel B is connected to the second dual-purpose signal line 19-2 via the acquisition terminal 1 of the second bidirectional switch 26-2; the third detection channel C is connected to the third dual-purpose signal line 19-3 via the acquisition terminal 1 of the third bidirectional switch 26-3; the fourth detection channel D is connected to the fourth dual-purpose signal line 19-4 via the acquisition terminal 1 of the fourth bidirectional switch 26-4; and the fifth detection channel E is connected to the fifth dual-purpose signal line 19-5 via the acquisition terminal 1 of the fifth bidirectional switch 26-5. Each detection channel A, B, C, D, and E is used to receive the temperature detection signal acquired by the temperature sensor 14 of the electrode unit 12 connected to the corresponding dual-purpose signal line 19. Furthermore, each detection channel A, B, C, D, and E is connected to the first power module 29, which provides the detection voltage to that detection channel A, B, C, D, and E, via a corresponding voltage divider resistor 24 within the adapter 20. The first power module 29 provides a DC signal.

[0074] In this embodiment, the first communication unit 27 is configured to acquire digital signals output by multiple sets of analog-to-digital converters 23.The digital signal is then sent to the electric field generator 30. The electric field generator 30 is also configured to control and adjust the voltage, current, or power of the AC signal provided to the plurality of electrode units 12 of the electrode pad 10 according to the received digital signal. For example, when any of the received digital signals exceeds a preset threshold, it indicates that the temperature detected by at least one temperature sensor 14 in the electrode pad 10 at the corresponding dielectric element 15 on the human body surface exceeds the preset threshold temperature (e.g., 41°C, 42°C, etc.). At this time, the voltage, current, or power of the AC signal output by the electric field generator 30 can be appropriately reduced to avoid the electrode units 12 of the electrode pad 10 becoming too hot when the AC signal is applied, causing low-temperature burns to the patient's skin. The aforementioned preset threshold temperature and preset threshold can be determined according to human safety thresholds. The first communication unit 27 is controlled by the first controller 22 and serially transmits digital signals converted by multiple sets of analog-to-digital converters 23. In this embodiment, the preset temperature threshold can be a value within the range of 36℃-45℃.

[0075] Referring to Figures 4 and 5, in this embodiment, the first power module 29 is electrically connected to the second power module 31 of the electric field generator 30 and is configured to supply power to the first controller 22, multiple analog-to-digital converters 23, and the first communication unit 27 of the adapter 20. Each electrode 10 is connected to the adapter 20 by a first connector 40, which is adapted to connect the corresponding electrode 10 to the adapter 20. As shown in Figure 1, the first connector 40 includes a first plug 41 located at the end of the first cable 13 away from the electrode 10 and a first socket 42 located on the adapter 20. The first plug 41 and the first socket 42 are press-type spring connectors, that is, the first connector 40 connects the adapter 20 and the electrode 10 by means of a connector. Each first cable 13 has 5 wires electrically connected to the corresponding bidirectional switch 26 in the corresponding set of bidirectional switch 26 and 4 wires electrically connected to the corresponding grounding switch 25 in the corresponding set of grounding switches 25. That is, each first connector 40 is electrically connected to the corresponding set of bidirectional switch 26-1, 26-2, 26-3, 26-4, 26-5 and the corresponding set of grounding switches 25-1, 25-2, 25-3, 25-4 of the adapter 20 through 9 wires; and is connected to the electric field generator 30 through the corresponding AC signal line 28 of the adapter 20.

[0076] A second connector 50 is provided between the adapter 20 and the electric field generator 30. The second connector 50 is adapted to connect the electric field generator 30 to the adapter 20. The adapter 20 also includes a second cable 21 connected to the second connector 50. The second connector 50 includes a second plug 51 located at the end of the second cable 21 away from the first controller 22 and a connector on the electric field generator 30.The second socket 52. The second plug 51 and the second socket 52 are push-button spring connectors, that is, the second connector 50 connects the adapter 20 and the electric field generator 30 using a connector. Each first connector 40, such as X1, Y1, X2, Y2, is connected to the second connector 50 via a corresponding AC signal line 28. Each first connector 40, such as X1, Y1, X2, Y2, is connected to a corresponding set of grounding switches 25 and a corresponding set of analog-to-digital converters 23. Specifically, each first connector 40 is simultaneously connected to the second connector 50 and the corresponding set of analog-to-digital converters 23 via a corresponding set of bidirectional switching switches 26. Taking four electrode plates 10 as an example, the second cable 21 has eight wires: four wires 1 to 4, each electrically connected to a corresponding AC signal line 28 for transmitting AC signals; one wire 5, electrically connected to the data receiving line RX of the first communication unit 27; one wire 6, electrically connected to the data transmitting line TX of the first communication unit 27; one wire 7, electrically connected to the VCC power line of the first power module 29; and one wire 8, electrically connected to the GND line of the first power module 29. The second connector 50 is connected to the first communication unit 27 via the data receiving line RX and the data transmitting line TX. The VCC pin of the second connector 50 is connected to the VVC power line of the first power module 29, and the GND pin of the second connector 50 is connected to the GND line of the first power module 29 and grounded. The VCC pin of the second connector 50 is also connected to the corresponding group of voltage regulators 24 and the corresponding group of analog-to-digital converters 23 via the VCC power line of the first power module 29.

[0077] Referring to FIG5, the electric field generator 30 includes: a second power supply module 31, a second controller 32, an AC signal generator 34, a second communication unit 33, and a set of AC signal switches 35. The VCC pin of the second connector 50 is also electrically connected to the VCC power line of the second power supply module 31, and the GND pin of the second connector 50 is grounded through the GND line of the second power supply module 31. The second power supply module 31 is also connected to and supplies power to the second controller 32 and the AC signal generator 34 respectively. The second communication unit 33 is electrically connected to the wire 5 of the second connector 50 through its data receiving line RX and to the wire 6 of the second connector 50 through its data transmitting line TX, thereby realizing information interaction between the electric field generator 30 and the adapter 20. The second controller 32 is also electrically connected to the second communication unit 33, the AC signal generator 34, and a set of AC signal switches 35. The second controller 32 is configured to control the opening and closing of each AC signal switch 35 in a set of AC signal switches 35, and to adjust the relevant parameters of the AC signal applied by the AC signal generator 34, based on the relevant digital signals received from the adapter 20 by the second communication unit 33. (See page 14 / 41 of the manual, CN 121288197 A)The generator 34 is electrically connected to the conductors 1 to 4 of the second connector 50 for transmitting AC signals via a set of AC signal switches 35. The set of AC signal switches 35 includes multiple AC signal switches 35, each corresponding to one of the electrode plates 10. Each AC signal switch 35 is electrically connected to a corresponding conductor 1, 2, 3, or 4 of the second connector 50 via an AC signal wiring 36, and is also electrically connected to the corresponding electrode plate 10 via the corresponding conductors 1, 2, 3, or 4 of the second connector 50, to transmit AC signals to each electrode plate 10. The AC signal generator 34 is electrically connected to the set of AC signal switches 35 via a set of AC signal wiring 36.

[0078] Specifically, the number of AC signal switches 35 in the electric field generator 30 is related to the number of electrode plates 10. In this embodiment, the number of AC signal switches 35 is equal to the number of electrode plates 10, and both are four. The AC signal switch 35 includes a first AC signal switch 35-1, a second AC signal switch 35-2, a third AC signal switch 35-3, and a fourth AC signal switch 35-4, which are electrically connected to the wires 1 to 4 of the second connector 50 via corresponding AC signal wiring 36. One end of the first AC signal switch 35-1 is electrically connected to the AC signal generator 34 via the first AC signal wiring 36-1 of the electric field generator 30. The other end is electrically connected via the first AC signal wiring 36-1 to the corresponding AC signal transmission wire 1 in the second connector 50, and via the wire 1 of the second connector 50 to the AC signal line 28 located at port X1 of the adapter 20. The AC signal line 28 located at port X1 of the adapter 20 is electrically connected to the first connector 40. The first connector 40 located at port X1 of the adapter 20 is electrically connected to the corresponding electrode plate 10, thereby controlling whether the AC signal generator 34 supplies AC signal to the electrode plate 10 electrically connected to port X1 of the adapter 20. The second AC signal switch 35-2 is electrically connected to the AC signal generator 34 via the second AC signal wiring 36-2 of the electric field generator 30, and the other end is electrically connected to the corresponding AC signal transmission wire 2 in the second connector 50 via the second AC signal wiring 36-2, and to the AC signal line 28 at port Y1 of the adapter 20 via the wire 2 of the second connector 50. The AC signal line 28 at port Y1 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 at port Y1 of the adapter 20 is electrically connected to the corresponding electrode plate 10, so as to control whether the AC signal generator 34 transmits AC signal to the electrode plate 10 electrically connected to port Y1 of the adapter 20; the third AC signal switch 35-3 is electrically connected to the AC signal generator 34 via the third AC signal wiring 36-3 of the electric field generator 30, and the other end is electrically connected to the second connector 34 via the third AC signal wiring 36-3.The corresponding AC signal transmission wire 3 in the device 50 is electrically connected to the AC signal line 28 located at port X2 of the adapter 20 via the wire 3 of the second connector 50. The AC signal line 28 located at port X2 of the adapter 20 is electrically connected to the first connector 40. The first connector 40 located at port X2 of the adapter 20 is electrically connected to the corresponding electrode plate 10 to control whether the AC signal generator 34 transmits AC signal to the electrode plate 10 electrically connected to port X2 of the adapter 20; the fourth AC signal switch 35-4 One end is electrically connected to the AC signal generator 34 via the fourth AC signal wiring 36-4 of the electric field generator 30, and the other end is electrically connected to the corresponding AC signal transmission wire 4 in the second connector 50 via the fourth AC signal wiring 36-4, and to the AC signal line 28 located at port Y2 of the adapter 20 via the wire 4 of the second connector 50. The AC signal line 28 located at port Y2 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 located at port Y2 of the adapter 20 is electrically connected to the corresponding electrode plate 10, so as to control whether the AC signal generator 34 transmits AC signal to the electrode plate 10 electrically connected to port Y1 of the adapter 20.

[0079] The working principle of the tumor electric field therapy system 100 of this embodiment will be described in detail below with reference to Figures 3 to 5.

[0080] Specifically, when it is necessary to detect the temperature of each electrode unit 12 of a certain electrode plate 10, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls the acquisition terminal 1 of each of the multiple bidirectional switching switches 26 of a set of bidirectional switching switches 26 electrically connected to the electrode plate 10 to be turned on and the input terminal 2 to be turned off, so as to disconnect the AC signal applied to the electrode plate 10; at the same time, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls each of the grounding switches 25 of a set of grounding switches 25 electrically connected to the electrode plate 10 to be turned on in sequence and time-division. When this specification 15 / 41 page 19 CN 121288197 A is used, the temperature detection signals collected by each temperature sensor 14 of each electrode unit 12 of each row of the electrode plate 10 can be collected in sequence and time-division through the multiple detection channels A, B, C, D, E of a set of analog-to-digital converters 23 corresponding to the electrode plate 10. Each detection channel A, B, C, D, and E of each group of analog-to-digital converters 23 simultaneously acquires only the temperature detection signal from the temperature sensor 14 of the corresponding electrode unit 12 in the same row of electrode plates 10. This temperature detection signal can be characterized by a voltage value. At any given time, only one of the four grounding switches 25 in the group of grounding switches 25 corresponding to the electrode plate 10 can be on, while the other three are off. Similarly, the five bidirectional switches in the group of bidirectional switching switches 26 corresponding to the group of analog-to-digital converters 23...All switches 26 are switched to their respective acquisition terminals 1 so that each dual-purpose signal line 19 of the electrode 10 is electrically connected to the corresponding detection channels A, B, C, D, and E of the corresponding group of analog-to-digital converters 23 and thus conducts. With this configuration, the group of analog-to-digital converters 23 can acquire the voltage values ​​of the temperature sensors 14 of each electrode unit 12 in the same row group that are shorted by a grounding line 18 corresponding to the grounding switch 25.

[0081] Specifically, when the first grounding switch 25-1 is closed, and the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4 are all open, and the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 are all switched to their respective acquisition terminals 1, the temperature sensors 14 of the electrode units 12-1 to 12-5 in the first row group are energized, and the temperature sensors 14 of the electrode units 12-6 to 12-20 in the remaining row groups are de-energized. The first detection channel A in the analog-to-digital converter 23 of this group short-circuits the signal terminals 14- of the temperature sensors 14 of the electrode units 12-1, 12-6, 12-11, and 12-16. 2. Since only the grounding terminal 14-1 of the temperature sensor 14 in electrode unit 12-1 is connected to ground, while the grounding terminals 14-1 of the temperature sensors 14 in electrode units 12-6, 12-11, and 12-16 are disconnected, and each electrode unit 12 has a diode 16 connected in series with the temperature sensor 14, the other temperature sensors 14 in the first row will not affect the resistance value of the temperature sensor 14 in electrode unit 12-1. Therefore, only the temperature sensor 14 of electrode unit 12-1 is effectively operating on the first detection channel A of this group of analog-to-digital converters 23. The temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 in electrode unit 12-1. Similarly, the voltage value collected on the second detection channel B of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-2. The voltage value collected on the third detection channel C of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-3. The voltage value collected on the fourth detection channel D of the analog-to-digital converter 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-4. The voltage value collected on the fifth detection channel E of the analog-to-digital converter 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-5.

[0082] When the second grounding switch 25-2 is closed, the first grounding switch 25-1, the third grounding switch 25-3 and the fourth grounding switch 25-4 are all open, and the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, and the third bidirectional switching switch 26-3. When both the fourth bidirectional switching switch 26-4 and the fifth bidirectional switching switch 26-5 are switched to their respective acquisition terminals 1, the temperature sensors 14 of electrode units 12-6 to 12-10 in the second row group are energized, while the temperature sensors 14 of electrode units 12-1 to 12-5 and electrode units 12-11 to 12-20 in the remaining rows are de-energized. The first detection channel A in the analog-to-digital converter 23 of this group is short-circuited to electrode units 12-1, 12-6, 12-11, and 12-16. Since only the grounding terminal 14-1 of the temperature sensor 14 in electrode unit 12-6 is connected to ground, while the grounding terminals 14-1 of the temperature sensors 14 in electrode units 12-1, 12-11, and 12-16 are disconnected, and each electrode unit 12 has a diode 16 connected in series with the temperature sensor 14, the remaining temperature sensors 14 in the second row will not affect the resistance value of the temperature sensor 14 in electrode unit 12-6. Therefore, only the temperature sensor 14 in electrode unit 12-6 is effectively operating on the first detection channel A of this group of analog-to-digital converters 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 in electrode unit 12-6. Similarly, the voltage value collected on the second detection channel B of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-7. The voltage value acquired on the third detection channel C of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-8. The voltage value acquired on the fourth detection channel D of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-9. The voltage value acquired on the fifth detection channel E of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-10.

[0083] When the third grounding switch 25-3 is closed, the first grounding switch 25-1, the second grounding switch 25-2, and the fourth grounding switch 25-4 are all open, and the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 are all switched to their respective acquisition terminals 1, the temperature sensors 14 of the electrode units 12-11 to 12-15 in the third row group are energized, and the temperature sensors 14 of the electrode units 12-11 to 12-10 and the electrode units 12-16 to 12-20 in the other rows are de-energized. The first detection channel A in the analog-to-digital converter 23 of this group short-circuits electrode units 12-1, 12-6, 12-11, and 12-15.Since only the grounding terminal 14-1 of the temperature sensor 14 in electrode unit 12-11 is connected to ground, while the grounding terminals 14-1 of the temperature sensors 14 in electrode units 12-1, 12-6, and 12-16 are disconnected, and each electrode unit 12 has a diode 16 connected in series with the temperature sensor 14, the other temperature sensors 14 in the third row will not affect the resistance value of the temperature sensor 14 in electrode unit 12-11. Therefore, only the temperature sensor 14 in electrode unit 12-11 is effectively operating on the first detection channel A of this group of analog-to-digital converters 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 in electrode unit 12-11. Similarly, the voltage value collected on the second detection channel B of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-12. The voltage value acquired on the third detection channel C of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode units 12-13. The voltage value acquired on the fourth detection channel D of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode units 12-14. The voltage value acquired on the fifth detection channel E of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode units 12-15.

[0084] When the fourth grounding switch 25-4 is closed, the first grounding switch 25-1, the second grounding switch 25-2, and the third grounding switch 25-3 are all open, and the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 are all switched to their respective acquisition terminals 1. The temperature sensors 14 of the electrode units 12-16 to 12-20 in the fourth row group are powered on, while the temperature sensors 14 of the electrode units 12-1 to 12-15 in the other row groups are de-powered. The first detection channel A in the analog-to-digital converter 23 of this group short-circuits the signal terminals 14-2 of the temperature sensors 14 of the electrode units 12-1, 12-6, 12-11, and 12-16. Since only the grounding terminal 14-1 of the temperature sensor 14 in electrode unit 12-16 is connected to ground, while the grounding terminals 14-1 of the temperature sensors 14 in electrode units 12-1, 12-6, and 12-11 are disconnected, and each electrode unit 12 has a diode 16 connected in series with the temperature sensor 14, the remaining temperature sensors 14 in the fourth row will not affect the resistance value of the temperature sensor 14 in electrode unit 12-16. Therefore, only the temperature sensor 14 in electrode unit 12-16 is effectively operating on the first detection channel A of this group of analog-to-digital converters 23. At this time, the temperature detection signal (voltage) collected by the first detection channel A is...The voltage value () is the voltage value of temperature sensor 14 in electrode units 12-16. Similarly, the voltage value collected on the second detection channel B in this group of analog-to-digital converters 23 is the voltage value of temperature sensor 14 in electrode units 12-17. The voltage value collected on the third detection channel C in this group of analog-to-digital converters 23 is the voltage value of temperature sensor 14 in electrode units 12-18. The voltage value collected on the fourth detection channel D in this group of analog-to-digital converters 23 is the voltage value of temperature sensor 14 in electrode units 12-19. The voltage value collected on the fifth detection channel E in this group of analog-to-digital converters 23 is the voltage value of temperature sensor 14 in electrode units 12-20. Therefore, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 can control a set of bidirectional switching switches 26 and a set of grounding switches, all of which are electrically connected to a certain electrode plate 10, to acquire the temperature detection signals of the temperature sensors 14 of all electrode units 12 of that electrode plate 10. Similarly, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 of other electrode plates 10 can be obtained.

[0085] The first controller 22, multiple sets of analog-to-digital converters 23, and multiple sets of bidirectional switching switches 26 can automatically perform operations through pre-programmed program code. For example, the first controller 22 first controls all bidirectional switching switches 26 in the corresponding set to switch to the acquisition terminal 1, so that the acquisition terminals 1 of these bidirectional switching switches 26 are all turned on and the input terminals 2 are all turned off, so that each dual-purpose signal line 19 of the corresponding electrode plate 10 is electrically connected to the corresponding set of analog-to-digital converters 23. Then, it closes the first grounding switch 25-1 in the corresponding set of grounding switches 25, and opens the remaining second grounding switches 25-2, third grounding switches 25-3 to fourth grounding switches 25-4 in the set of grounding switches 25. During this period, each detection channel A, B, C of the set of analog-to-digital converters 23 is connected. D and E acquire the temperature detection signals of each temperature sensor 14 of each electrode unit 12 located in the first row group of the corresponding electrode sheet 10, convert them into digital signals, and store them in a separately set memory. Then, after a preset interval, the first controller 22 closes the second grounding switch 25-2 in the group of grounding switches 25, and opens the first grounding switch 25-1, the third grounding switch 25-3, and the fourth grounding switch 25-4 in the group of grounding switches 25. During this period, the detection channels A, B, C, D, and E of the group of analog-to-digital converters 23 acquire the temperature detection signals of each temperature sensor 14 of each electrode unit 12 located in the second row group. By sequentially turning on each grounding switch 25 in the group of grounding switches 25, the temperature detection signals of all temperature sensors 14 in each row group of the electrode sheet 10 can be obtained. Similarly, through this operation, the temperature detection signals of all temperature sensors 14 on at least one pair of electrode sheets 10 can be obtained.

[0086] The tumor electric field therapy system 100 of this application can achieve real-time and comprehensive monitoring of the temperature of all electrode units 12 on the electrode sheet 10 without increasing the weight of the electrode sheet 10 or the number of wire cores of the first cable 13 electrically connected to the electrode sheet 10. It can then determine whether the electrode sheet 10 is qualified based on the obtained temperature detection signal; or determine whether the temperature sensor 14 of the electrode sheet 10 is faulty or abnormal based on the obtained temperature detection signal, and determine whether the electrode sheet 10 needs to be replaced based on the number of faulty or abnormal temperature sensors 14; or identify the electrode sheet type based on the obtained temperature detection signal if the electrode sheet is qualified; or determine whether the electrode unit 12 of the electrode sheet 10 is overheated based on the obtained temperature detection signal if the electrode sheet is qualified, and then control the AC signal applied to the electrode sheet 10 or the corresponding column of electrode units 12 of the electrode sheet 10, thereby avoiding low-temperature burns to the patient's body surface during tumor treatment through the electrode sheet 10. Furthermore, the flexible circuit board 11 of the electrode sheet 10 of this application is electrically connected to the dielectric element 15 of the same electrode unit 12 and the signal terminal 14-2 of the temperature sensor 14 through the same dual-purpose signal line 19. This allows for the transmission of both AC signals and DC signals for temperature signal acquisition, as well as the acquired temperature detection signal, via the dual-purpose signal line 19. Simultaneously, it significantly reduces the number of conductive traces (grounding line 18, dual-purpose signal line 19) laid on it, reducing the wiring difficulty of the flexible circuit board 11, simplifying the manufacturing process, reducing the weight of the flexible circuit board 11, and lowering manufacturing costs. The electrode sheet 10 of this application can also switch between applying AC signals for tumor treatment and transmitting DC signals for temperature acquisition and transmitting the acquired temperature detection signal through a combination of a grounding switch 25 electrically connected to the grounding line 18 and a bidirectional switching switch 26 electrically connected to the dual-purpose signal line 19.

[0087] When it is necessary to apply an AC signal to the patient through each electrode unit 12 of an electrode pad 10, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls all grounding switches 25 in a set of grounding switches 25 corresponding to the electrode pad 10 to be disconnected, and at the same time controls all bidirectional switching switches 26 in a set of bidirectional switching switches 26 corresponding to the electrode pad 10 to be switched to their respective input terminals 2, so that the acquisition terminals 1 of these bidirectional switching switches 26 are all disconnected and the input terminals 2 are all turned on, so that each dual-purpose signal line 19 of the electrode pad 10 is electrically connected to an AC signal line 28 corresponding to the adapter 20 and the electrode pad instruction manual page 18 / 41 22 CN 121288197 A 10, thereby transmitting the AC signal to each electrode unit 12 of the electrode pad 10. When detectedWhen the temperature detection signals of the temperature sensors 14 of all electrode units 12 of the electrode plate 10 are much lower than the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 controls the AC signal generator 34 through its second controller 32 to continue generating an AC signal with an increased voltage or current amplitude or a constant voltage or current amplitude, and then transmits it to the corresponding counter electrode plate 10 through a corresponding AC signal line 28 of the adapter 20, so that the counter electrode plate 10 continues to apply an AC signal; when the detected temperature detection signals of the temperature sensors 14 of all electrode units 12 of the electrode plate 10 are lower than but close to the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 can reduce the voltage or current of the AC signal generated by the AC signal generator 34 through the second controller 32, thereby reducing the voltage or current of the AC signal applied to the counter electrode plate 10; when a certain electrode plate 10 is detected to have an electrical... When the temperature detection signal of the temperature sensor 14 of the electrode unit 12 exceeds the preset temperature threshold, the electric field generator 30 controls the AC signal switch 35 electrically connected to the electrode 10 to disconnect via the second controller 32, thereby stopping the application of AC signals to the electrode 10; or the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 controls all bidirectional switching switches 26 in a set of bidirectional switching switches 26 electrically connected to the electrode 10 to switch from their input terminals 2 to their acquisition terminals 1, that is, controlling all bidirectional switching acquisition terminals 1 of all bidirectional switching switches 26 in a set of bidirectional switching switches 26 electrically connected to the electrode 10 to be fully turned on and all input terminals 2 to be fully turned off, thereby stopping the application of AC signals to the electrode 10. An AC signal is applied; or, when the temperature detection signal of the temperature sensor 14 of an electrode unit 12 on a certain electrode plate 10 is detected to be greater than a preset temperature threshold, the second controller 32 of the electric field generator 30 controls the AC signal switch 35 electrically connected to the electrode plate 10 to remain on, and the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 controls a bidirectional switching switch 26 electrically connected to the electrode unit 12 on the electrode plate 10 to switch from its input terminal 2 to its acquisition terminal 1. Simultaneously, the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 controls the remaining bidirectional switching switches 26 electrically connected to the electrode units 12 in different columns from the electrode units 12 whose temperature detection signals do not exceed the preset temperature threshold to remain electrically connected to their respective input terminals 2, so as to stop supplying power to all electrode units 12 in the column where the temperature detection signal of the electrode unit 12 on the electrode plate 10 exceeds the preset temperature threshold. An alternating current signal is applied, and an alternating current signal continues to be applied to the remaining column electrode units 12 where the temperature detection signal of the electrode sheet 10 does not exceed a preset temperature threshold. This enables the tumor electric field therapy system 100 to utilize alternating current signals based on temperature detection signals.A control method that applies the signal in sections. When an AC signal is applied, all grounding switches 25 are disconnected.

[0088] In this embodiment, the grounding switches 25 that are electrically connected to the multiple grounding lines 18 of the electrode plate 10 and the bidirectional switching switches 26 that are electrically connected to the multiple dual-purpose signal lines 19 of the electrode plate 10 are all located in the adapter 20. However, in other embodiments, the grounding switches 25 that are electrically connected to the grounding lines 18 and the bidirectional switching switches 26 that are electrically connected to the dual-purpose signal lines 19 can also be located on the electrode plate 10 or in the electric field generator 30, which will not be described in detail here. In addition, the analog-to-digital converter 23 located in the adapter 20 can also be located in the electric field generator 30 and directly controlled by the second controller 32.

[0089] This application also provides other embodiments of the electrode plate 10. The differences between the multiple embodiments are mainly the different number of electrode units 12 and / or the different electrical connection arrangements of the electrode units 12, which will be described separately below.

[0090] Referring to FIG6, the electrode sheet 10A of the second embodiment has 19 electrode units 12. The flexible circuit board 11A arranges these 19 electrode units 12 in four rows and five columns in electrical connection, wherein each of the three rows has 5 electrode units 12 and the remaining row has 4 electrode units 12. The electrode sheet 10A includes 4 grounding wires 18 and 5 dual-purpose signal lines 19. Each grounding wire 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group. Each dual-purpose signal line 19 is short-circuited to the dielectric element 15 of each electrode unit 12 in each column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals. The four grounding wires 18 of electrode sheet 10A include first grounding wire 18-1, second grounding wire 18-2, third grounding wire 18-3 and fourth grounding wire 18-4. The first row group includes electrode units 12-1 to 12-5, the second row group includes electrode units 12-6 to 12-10, the third row group includes electrode units 12-11 to 12-15, and the fourth row group includes electrode units 12-16 to 12-19. Specifically, the first grounding wire 18-1 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each of the five electrode units 12 from electrode unit 12-1 to electrode unit 12-5 in the first row group; the second grounding wire 18-2 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each of the five electrode units 12 from electrode unit 12-6 to electrode unit 12-10 in the second row group; and the third grounding wire 18-3 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each of the five electrode units 12 from electrode unit 12-11 to electrode unit 12-15 in the third row group.Ground terminal 14-1 is grounded, and the fourth grounding line 18-4 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each of the four electrode units 12 from electrode unit 12-16 to electrode unit 12-19 in the fourth row group. In short, each grounding line 18 short-circuits and grounds the grounding terminal 14-1 of the temperature sensor 14 of all electrode units 12 in each row group.

[0091] The five dual-purpose signal lines 19 of the electrode sheet 10A include the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the four electrode units 12 (electrode units 12-1, 12-6, 12-11, and 12-16) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the four electrode units 12 (electrode units 12-2, 12-7, 12-12, and 12-17) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric element 15 of each of the four electrode units 12 (electrode units 12-3, 12-8, 12-13, and 12-18) and the signal terminal 14-2 of each of their respective temperature sensors 14; the fourth dual-purpose signal line 19-4... One end of the fifth dual-purpose signal line 19-5 is simultaneously connected to the dielectric element 15 of each of the four electrode units 12 (electrode units 12-4, 12-9, 12-14, and 12-19) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the fifth dual-purpose signal line 19-5 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-5, 12-10, and 12-15) and the signal terminal 14-2 of their respective temperature sensors 14. In short, each dual-purpose signal line 19 short-circuits the dielectric element 15 and the signal terminal 14-2 of each electrode unit 12 located in the same column group and connects them to the adapter 20.

[0092] The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4 of the adapter 20 are electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, the third grounding wire 18-3, and the fourth grounding wire 18-4 of the electrode plate 10A respectively via the first connector 40A. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch on the adapter 20 are also connected to the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 25-4.The switch 26-5 is electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5 of the electrode 10A via the first connector 40A. The tumor electric field therapy system formed by the electrode 10A, the adapter 20, and the electric field generator 30 operates in the same way as the aforementioned tumor electric field therapy system 100. When all grounding switches 25 are open and the input terminals 2 and acquisition terminals 1 of all bidirectional switching switches 26 are closed, all dual-purpose signal lines 19 and AC signal lines 28 are connected, and all electrode units 12 are connected to AC signals. When the acquisition terminals 1 and input terminals 2 of all bidirectional switching switches 26 are closed, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25.

[0093] Referring to FIG7, the electrode sheet 10B of the third embodiment is provided with 17 electrode units 12. The flexible circuit board 11B arranges these 17 electrode units 12 in four rows and five columns in electrical connection, wherein each of the three rows has 5 electrode units 12 and the remaining row has 2 electrode units 12. The electrode sheet 10B includes 4 grounding wires 18 and 5 dual-purpose signal lines 19. Each grounding wire 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group. Each dual-purpose signal line 19 is short-circuited to the dielectric element 15 of each electrode unit 12 in each column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals. The four grounding wires 18 of the electrode sheet 10B include a first grounding wire 18-1, a second grounding wire 18-2, a third grounding wire 18-3 and a fourth grounding wire 18-4. The first row group includes electrode units 12-1 to 12-5, the second row group includes electrode units 12-6 to 12-10, the third row group includes electrode units 12-11 to 12-15, and the fourth row group includes electrode units 12-16 to 12-17. Specifically, the first grounding wire 18-1 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each of the five electrode units 12 from electrode unit 12-1 to electrode unit 12-5 in the first row group; the second grounding wire 18-2 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each of the five electrode units 12 from electrode unit 12-6 to electrode unit 12-10 in the second row group; the third grounding wire 18-3 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each of the five electrode units 12 from electrode unit 12-11 to electrode unit 12-15 in the third row group; and the fourth grounding wire 18-4 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each of the five electrode units 12 from electrode unit 12-16 to electrode unit 12-17 in the fourth row group.The grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 is grounded. In short, each grounding line 18 short-circuits and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group.

[0094] The five dual-purpose signal lines 19 of the electrode sheet 10B include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the four electrode units 12 (electrode units 12-1, 12-6, 12-11, and 12-16) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the four electrode units 12 (electrode units 12-2, 12-7, 12-12, and 12-17) and the signal terminal 14-2 of each of their respective temperature sensors 14; the third dual-purpose signal line 19-3... One end of the first dual-purpose signal line 19-4 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-3, 12-8, and 12-13) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-4 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-4, 12-9, and 12-14) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-5 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-5, 12-10, and 12-15) and the signal terminal 14-2 of each of their respective temperature sensors 14. In short, each dual-purpose signal line 19 short-circuits the dielectric element 15 and the signal terminal 14-2 of each of the electrode units 12 located in the same column group and connects them to the adapter 20.

[0095] The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4 of the adapter 20 are electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, the third grounding wire 18-3, and the fourth grounding wire 18-4 of the electrode plate 10B respectively via the first connector 40B. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 on the adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5 of the electrode plate 10B respectively via the first connector 40B.Connection. The tumor electric field therapy system formed by electrode 10B, adapter 20 and electric field generator 30 operates in the same way as the aforementioned tumor electric field therapy system 100. When all grounding switches 25 are open and the input terminals 2 of all bidirectional switching switches 26 are on and the acquisition terminals 1 are off, all dual-purpose signal lines 19 and AC signal lines 28 are connected, and all electrode units 12 are connected to AC signals. When the acquisition terminals 1 of all bidirectional switching switches 26 are on and the input terminals 2 are off, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25.

[0096] Referring to FIG8, the electrode sheet 10C of the fourth embodiment is provided with 17 electrode units 12, just like the electrode sheet 10B of the third embodiment. However, the specific circuit connection arrangement of each electrode unit 12 is different. The flexible circuit board 11C of the electrode sheet 10C also arranges these 17 electrode units 12 in four rows and five columns in electrical connection. However, one row has 5 electrode units 12, and the remaining three rows each have 4 electrode units 12. The electrode sheet 10C includes 4 grounding wires 18 and 5 dual-purpose signal lines 19. Each grounding wire 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group. Each dual-purpose signal line 19 is short-circuited to the dielectric element 15 of each electrode unit 12 in each column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals. The four grounding wires 18 of the electrode sheet 10C include a first grounding wire 18-1, a second grounding wire 18-2, a third grounding wire 18-3, and a fourth grounding wire 18-4. The first row group includes electrode units 12-1 to 12-5, the second row group includes electrode units 12-6 to 12-9, the third row group includes electrode units 12-10 to 12-13, and the fourth row group includes electrode units 12-14 to 12-17. Specifically, the first grounding wire 18-1 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each of the five electrode units 12 from electrode unit 12-1 to electrode unit 12-5 in the first row group; the second grounding wire 18-2 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each of the four electrode units 12 from electrode unit 12-6 to electrode unit 12-9 in the second row group; the third grounding wire 18-3 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each of the four electrode units 12 from electrode unit 12-10 to electrode unit 12-13 in the third row group; and the fourth grounding wire 18-4 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each of the four electrode units 12 from electrode unit 12-14 to electrode unit 12-17 in the fourth row group. In short, each grounding wire 18 will correspond to...The grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in the row group are shorted together and grounded.

[0097] The five dual-purpose signal lines 19 of the electrode sheet 10C include the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4 and the fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the four electrode units 12 (electrode units 12-1, 12-6, 12-10, and 12-14) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the four electrode units 12 (electrode units 12-2, 12-7, 12-11, and 12-15) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric element 15 of each of the four electrode units 12 (electrode units 12-3, 12-8, 12-12, and 12-16) and the signal terminal 14-2 of each of their respective temperature sensors 14; the fourth dual-purpose signal line 19-4... One end of the fifth dual-purpose signal line 19-5 is connected to the dielectric element 15 of each of the four electrode units 12 (electrode units 12-4, 12-9, 12-13, and 12-17) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the fifth dual-purpose signal line 19-5 is connected to the dielectric element 15 of one electrode unit 12 and the signal terminal 14-2 of its temperature sensor 14. In short, each dual-purpose signal line 19 short-circuits the dielectric element 15 and the signal terminal 14-2 of each electrode unit 12 located in the same column group and connects them to the adapter 20.

[0098] The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4 of the adapter 20 are electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, the third grounding wire 18-3, and the fourth grounding wire 18-4 of the electrode plate 10C respectively via the first connector 40C. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 of the adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5 of the electrode plate 10C respectively via the first connector 40C. The working mode of the tumor electric field therapy system formed by the electrode plate 10C, the adapter 20, and the electric field generator 30 is the same as the aforementioned tumor electric field therapy system.Similar to the tumor electric field therapy system 100, when all grounding switches 25 are open and the input terminals 2 and acquisition terminals 1 of all bidirectional switching switches 26 are open, all dual-purpose signal lines 19 and AC signal lines 28 are connected, and all electrode units 12 are connected to AC signals; when the acquisition terminals 1 and input terminals 2 of all bidirectional switching switches 26 are open, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25 in sequence.

[0099] Referring to FIG9, the tumor electric field therapy system 100D of the fifth embodiment of this application is shown. The difference between it and the tumor electric field therapy system 100 described in FIG1 is that: this embodiment uses the electrode sheet 10D of the fifth embodiment and the adapter 20 and electric field generator 30 shown in FIG1 for electrical connection. In this embodiment, there are also four electrode plates 10D, which are respectively connected to the first socket 42 of the adapter 20 via a first plug 41D located at the end of the first cable 13D. Each electrode plate 10D also includes multiple electrode units 12D that are both axially symmetrical and centrally aligned, several connecting portions 111D located between adjacent electrode units 12, and wiring portions 112D that are electrically connected to the first cable 13D; however, the wiring portions 112D extend from an electrode unit 12 outward from the electrode array (unlabeled) and are perpendicular to a connecting portion 111D. The first cable 13D has 8 core wires.

[0100] The electrode units 12D of this electrode plate 10D have the same structure as the electrode units 12 in the aforementioned embodiment, the only difference being that the number of electrode units 12 in this embodiment is 13, and they are arranged in five rows and five columns in space. Specifically, the first and last rows each have two electrode units 12, located in the second and fourth columns respectively; the middle three rows each have three electrode units 12, located in the first, third, and fifth columns respectively. There are three electrode units 12 located at the center of the electrode array (unlabeled), specifically the three electrode units 12 located in the third column of the second row, the third column of the third row, and the third column of the third row; the rest are electrode units 12 located on the periphery of the electrode array (unlabeled). In the outermost electrode units 12, adjacent electrode units 12 are connected by connecting parts 111D. The electrode unit 12 located in the second row and third column is connected to the electrode unit 12 located in the first row and second row and adjacent to it, respectively, by connecting parts 111D. The electrode unit 12 located in the fourth row and third column is connected to the electrode unit 12 located in the fourth row and fifth row and adjacent to it, respectively, by connecting parts 111D. The electrode unit 12 located in the third row and third column is also connected to the electrode unit 12 located adjacent to it in the row and column directions by connecting parts 111D. The outermost electrode units 12 are connected in pairs by connecting parts 111D to form an octagonal ring structure.

[0101] Figure 10 is a schematic diagram of the circuit connection between the electrode sheet 10D of the fifth embodiment of the tumor electric field therapy system 100D shown in Figure 9 and the adapter 20 of the first embodiment shown in Figure 1. The circuit description below uses the electrode sheet 10D of the fifth embodiment as an example. In terms of electrical connection, the flexible circuit board 11D of the electrode sheet 10D arranges the 13 electrode units 12 in three rows and three columns, with each of the two rows having 5 electrode units 12 and the remaining row having 3 electrode units 12. The electrode sheet 10D includes 3 grounding lines 18 and 5 dual-purpose signal lines 19. Each grounding line 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group. Each dual-purpose signal line 19 is short-circuited to the dielectric element 15 of each electrode unit 12 in each column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals.

[0102] The three grounding wires 18 of the electrode sheet 10D are the first grounding wire 18-1, the second grounding wire 18-2, and the third grounding wire 18-3. In the three rows of the electrode sheet 10D, the first row includes electrode units 12-1 to 12-5, the second row includes electrode units 12-6 to 12-10, and the third row includes electrode units 12-11 to 12-13. Specifically, the first grounding wire 18-1 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-1 to 12-5 in the first row; the second grounding wire 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-6 to 12-10 in the second row; and the third grounding wire 18-3 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-11 to 12-13 in the third row. In short, each grounding wire 18 short-circuits and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group.

[0103] The five dual-purpose signal lines 19 of the electrode sheet 10D include the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4 and the fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode unit 12-1, electrode unit 12-6, and electrode unit 12-11) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12-2, electrode unit 12-7, and electrode unit 12-12 and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the electrode unit... (Page 23 / 41, CN)121288197 A 12-3, electrode units 12-8, and electrode units 12-13 each have their respective dielectric elements 15 and signal terminals 14-2 of their respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is simultaneously connected to the dielectric elements 15 and signal terminals 14-2 of the respective temperature sensors 14 of electrode units 12-4 and 12-9 respectively; one end of the fifth dual-purpose signal line 19-5 is simultaneously connected to the dielectric elements 15 and signal terminals 14-2 of the respective temperature sensors 14 of the respective electrode units 12-5 and 12-10 respectively. In short, each dual-purpose signal line 19 short-circuits the dielectric elements 15 and signal terminals 14-2 of the respective temperature sensors 14 of each electrode unit 12 located in the same column group and connects them to the adapter 20.

[0104] The first grounding switch 25-1, the second grounding switch 25-2, and the third grounding switch 25-3 of the adapter 20 are electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, and the third grounding wire 18-3 of the electrode plate 10D respectively via the first connector 40D. The fourth grounding switch 25-4 is in an idle and disconnected state. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 of the adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5 of the electrode plate 10D respectively via the first connector 40D.

[0105] The tumor electric field therapy system formed by the electrode pads 10D, the adapter 20, and the electric field generator 30 operates in the same manner as the aforementioned tumor electric field therapy system 100. When all grounding switches 25 are open and the input terminals 2 of all bidirectional switching switches 26 are on while the acquisition terminals 1 are off, all dual-purpose signal lines 19 and AC signal lines 28 are connected, and all electrode units 12 are connected to AC signals. When the acquisition terminals 1 of all bidirectional switching switches 26 are on while the input terminals 2 are off, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25 in sequence. Among them, no operation is required for the grounding switches 25-4 that are in an idle and open state.

[0106] Figure 11 shows another circuit connection diagram between the electrode sheet 10D of the fifth embodiment shown in Figure 9 and the adapter 20 of the first embodiment shown in Figure 1. In this embodiment, the flexible circuit board 11E of the electrode sheet 10E also arranges the 13 electrode units 12 in three rows and five columns in terms of electrical connection, except that each of the two rows has 4 electrode units 12, and the remaining one...Each row has five electrode units 12. The electrode sheet 10E also includes three grounding wires 18 and five dual-purpose signal lines 19. Each grounding wire 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group. Each dual-purpose signal line 19 is short-circuited to the dielectric element 15 of each electrode unit 12 in the same column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals. The three grounding wires 18 of the electrode sheet 10E include a first grounding wire 18-1, a second grounding wire 18-2, and a third grounding wire 18-3. The first row group includes electrode units 12-1 to 12-4, the second row group includes electrode units 12-5 to 12-8, and the third row group includes electrode units 12-9 to 12-13. Specifically, the first grounding wire 18-1 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-1 to electrode unit 12-4 in the first row group; the second grounding wire 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-5 to electrode unit 12-8 in the second row group; and the third grounding wire 18-3 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-9 to electrode unit 12-13 in the third row group. In short, each grounding wire 18 short-circuits and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group.

[0107] The five dual-purpose signal lines 19 of the electrode sheet 10E include the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode unit 12-1, electrode unit 12-5, and electrode unit 12-9) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode unit 12-2, electrode unit 12-6, and electrode unit 12-10) and the signal terminal 14-2 of page 28 of the instruction manual (page 24 / 41, CN 121288197 A). Each temperature sensor 14 has its own signal terminal 14-2; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-3, 12-7, and 12-11) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-4, 12-8, and 12-12) and the signal terminal 14-2 of their respective temperature sensors 14.Terminal 14-2; one end of the fifth dual-purpose signal line 19-5 is connected to the dielectric element 15 of the electrode unit 12-13 and the signal terminal 14-2 of its temperature sensor 14. In short, each dual-purpose signal line 19 short-circuits the signal terminals 14-2 of the dielectric element 15 and the temperature sensor 14 of each electrode unit 12 located in the same column group and connects them to the adapter 20.

[0108] The first grounding switch 25-1, the second grounding switch 25-2 and the third grounding switch 25-3 of the adapter 20 are electrically connected to the first grounding wire 18-1, the second grounding wire 18-2 and the third grounding wire 18-3 of the electrode plate 10E respectively through the first connector 40E, and the fourth grounding switch 25-4 is in an idle and open state. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 of the adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5 of the electrode plate 10E respectively via the first connector 40E.

[0109] The tumor electric field therapy system formed by the electrode 10E, the adapter 20, and the electric field generator 30 operates in the same way as the aforementioned tumor electric field therapy system 100. When all grounding switches 25 are open and the input terminals 2 of all bidirectional switching switches 26 are on and the acquisition terminals 1 are off, all dual-purpose signal lines 19 and AC signal lines 28 are on, and all electrode units 12 are connected to AC signals. When the acquisition terminals 1 of all bidirectional switching switches 26 are on and the input terminals 2 are off, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25. Among them, no operation is required for the grounding switches 25 that are in an idle and open state.

[0110] Figure 12 is similar to Figure 11, and it is also another circuit connection diagram for the electrode 10D shown in Figure 9 and the adapter 20 shown in Figure 1. Referring to Figure 12, the electrode pad 10F of the tumor electric field therapy system in the seventh embodiment has 13 electrode units 12, similar to the electrode pad 10D of the tumor electric field therapy system in the fifth embodiment. However, the specific circuit layout is different. The flexible circuit board 11F of the electrode pad 10F arranges these 13 electrode units 12 in four rows and four columns for electrical connection, with three rows each having four electrode units 12 and the remaining row having one electrode unit 12. The electrode pad 10F includes four grounding lines 18 and four dual-purpose signal lines 19. Each grounding line 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group. Each dual-purpose signal line 19 shorts the corresponding electrode unit 12 in a column group.The dielectric element 15 and the signal terminals 14-2 of each temperature sensor 14 are used to receive temperature detection signals or transmit AC signals. The four grounding lines 18 of the electrode sheet 10F include a first grounding line 18-1, a second grounding line 18-2, a third grounding line 18-3, and a fourth grounding line 18-4. The first row group includes electrode units 12-1 to 12-4, the second row group includes electrode units 12-5 to 12-8, the third row group includes electrode units 12-9 to 12-12, and the fourth row group includes electrode unit 12-13. Specifically, the first grounding wire 18-1 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-1 to electrode unit 12-4 in the first row group; the second grounding wire 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-5 to electrode unit 12-8 in the second row group; the third grounding wire 18-3 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-9 to electrode unit 12-12 in the third row group; and the fourth grounding wire 18-4 is used to ground the grounding terminal 14-1 of the temperature sensors 14 of electrode unit 12-13 in the fourth row group. In short, each grounding wire 18 short-circuits and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group.

[0111] The four dual-purpose signal lines 19 of the electrode sheet 10F include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3 and a fourth dual-purpose signal line 19-4. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 and the signal terminal 14-2 of each of the four electrode units 12 (electrode unit 12-1, electrode unit 12-5, electrode unit 12-9, and electrode unit 12-13) and their respective temperature sensors 14, respectively. One end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 and the signal terminal 14-2 of each of the three electrode units 12 (electrode unit 12-2, electrode unit 12-6, and electrode unit 12-10). One end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric element 15 and the temperature sensor 14 of each of the three electrode units 12 (electrode unit 12-3, electrode unit 12-7, and electrode unit 12-11). The signal terminal 14-2; one end of the fourth dual-purpose signal line 19-4 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode unit 12-4, electrode unit 12-8, and electrode unit 12-12) and the signal terminal 14-2 of each of their respective temperature sensors 14. In short, each dual-purpose signal line 19 connects the dielectric element 15 of each electrode unit 12 located in the same column group and its respective...The signal terminals 14-2 of the temperature sensor 14 are all shorted in parallel and used to connect to the adapter 20.

[0112] The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3 and the fourth grounding switch 25-4 of the adapter 20 are electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, the third grounding wire 18-3 and the fourth grounding wire 18-4 of the electrode plate 10F respectively through the first connector 40F. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3 and the fourth bidirectional switching switch 26-4 of the adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3 and the fourth dual-purpose signal line 19-4 respectively through the first connector 40F. The fifth bidirectional switching switch 26-5 is in an idle and disconnected state.

[0113] The tumor electric field therapy system formed by the electrode 10F, the adapter 20, and the electric field generator 30 operates in the same way as the aforementioned tumor electric field therapy system 100. When all grounding switches 25 are open and the input terminals 2 and acquisition terminals 1 of all bidirectional switching switches 26 are open, all dual-purpose signal lines 19 and AC signal lines 28 are connected, and all electrode units 12 are connected to AC signals. When the acquisition terminals 1 and input terminals 2 of all bidirectional switching switches 26 are open, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25. Among them, no operation is required for the bidirectional switching switches 26 that are in an idle and open state.

[0114] Figure 13 is similar to Figure 12, and it is also another circuit connection diagram for the electrode 10D shown in Figure 9 and the adapter 20 shown in Figure 1. Referring to Figure 13, the electrode sheet 10G of the tumor electric field therapy system in the eighth embodiment also has 13 electrode units 12, but the specific circuit layout is different. The flexible circuit board 11G of the electrode sheet 10G arranges these 13 electrode units 12 in four rows and four columns in electrical connection, with three rows each having 3 electrode units 12 and the remaining row having 4 electrode units 12. The electrode sheet 10G includes 4 grounding lines 18 and 4 dual-purpose signal lines 19. Each grounding line 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group. Each dual-purpose signal line 19 is short-circuited to the dielectric element 15 of each electrode unit 12 in the corresponding column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals. The four grounding wires 18 of the electrode sheet 10G include a first grounding wire 18-1, a second grounding wire 18-2, a third grounding wire 18-3, and a fourth grounding wire 18-4. The first row group includes electrode unit 12-1 to electrode unit 18-4.12-3, the second row group includes electrode units 12-4 to 12-6, the third row group includes electrode units 12-7 to 12-9, and the fourth row group includes electrode units 12-10 to 12-13. Specifically, the first grounding wire 18-1 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12-1 to 12-3 in the first row group; the second grounding wire 18-2 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12-4 to 12-6 in the second row group; the third grounding wire 18-3 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12-7 to 12-9 in the third row group; and the fourth grounding wire 18-4 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12-10 to 12-13 in the fourth row group. In short, each grounding wire 18 short-circuits and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group.

[0115] The four dual-purpose signal lines 19 of the electrode sheet 10G include the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, and the fourth dual-purpose signal line 19-4. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the four electrode units 12 (electrode units 12-1, 12-4, 12-7, and 12-10) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the four electrode units 12 (electrode units 12-2, 12-5, 12-8, and 12-11) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric element 15 of each of the four electrode units 12 (electrode units 12-3, 12-6, 12-9, and 12-12) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is connected to the dielectric element 15 of electrode unit 12-13 and the signal terminal 14-2 of temperature sensor 14. In short, each dual-purpose signal line 19 shorts in parallel the signal terminals 14-2 of the dielectric elements 15 and temperature sensors 14 of each electrode unit 12 located in the same column group and connects them to the adapter 20.

[0116] The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3 and the fourth grounding switch 25-4 of the adapter 20 are respectively connected to the first grounding wire 18-1, the second grounding wire 18-2 and the third grounding wire 18-2 of the electrode plate 10G through the first connector 40G.The three grounding wires 18-3 and the fourth grounding wire 18-4 are electrically connected one-to-one. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, and the fourth bidirectional switch 26-4 of the adapter 20 are electrically connected one-to-one with the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, and the fourth dual-purpose signal line 19-4 respectively through the first connector 40G. The fifth bidirectional switch 26-5 is in an idle and disconnected state.

[0117] The tumor electric field therapy system formed by the electrode pads 10G, the adapter 20, and the electric field generator 30 operates in the same way as the aforementioned tumor electric field therapy system 100. When all grounding switches 25 are open and the input terminals 2 and acquisition terminals 1 of all bidirectional switching switches 26 are closed, all dual-purpose signal lines 19 and AC signal lines 28 are connected, and all electrode units 12 are connected to AC signals. When the acquisition terminals 1 and input terminals 2 of all bidirectional switching switches 26 are closed, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25. Among them, no operation is required for the bidirectional switching switches 26 that are in an idle and open state.

[0118] Referring to Figures 14 and 15, the main difference between the tumor electric field therapy system 100H in this embodiment and the tumor electric field therapy system 100 is that the electrode sheet 10H of the ninth embodiment has 9 electrode units 12. In terms of spatial arrangement, the 9 electrode units 12 are arranged in a three-row, three-column array. In terms of electrical connection, the flexible circuit board 11H of the electrode sheet 10H arranges these 9 electrode units 12 in two rows and five columns, with one row having 5 electrode units 12 and the other row having 4 electrode units 12. The electrode sheet 10H includes 2 grounding lines 18 and 5 dual-purpose signal lines 19. Each grounding line 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group. Each dual-purpose signal line 19 is short-circuited to the dielectric element 15 of each electrode unit 12 in each column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals. The electrode plate 10H has two grounding wires 18, namely the first grounding wire 18-1 and the second grounding wire 18-2. In the two rows of the electrode plate 10H, the first row includes electrode units 12-1 to 12-5, and the second row includes electrode units 12-6 to 12-9. Specifically, the first grounding wire 18-1 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12-1 to 12-5 in the first row; the second grounding wire 18-2 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12-6 to 12-9 in the second row. In short...Each grounding wire 18 short-circuits and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group.

[0119] The five dual-purpose signal lines 19 of the electrode sheet 10H include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric elements 15 of the two electrode units 12, namely electrode unit 12-1 and electrode unit 12-6, and to the specification page 27 / 41, page 31, CN 121288197 A. Each temperature sensor 14 has a signal terminal 14-2; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the two electrode units 12 (electrode unit 12-2 and electrode unit 12-7) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric element 15 of each of the two electrode units 12-3 and electrode unit 12-8 and the signal terminal 14-2 of their respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is simultaneously connected to the dielectric element 15 of each of the two electrode units 12-4 and electrode unit 12-9 and the signal terminal 14-2 of their respective temperature sensors 14; one end of the fifth dual-purpose signal line 19-5 is simultaneously connected to the dielectric element 15 of the electrode unit 12-5 and the signal terminal 14-2 of the temperature sensor 14. In short, each dual-purpose signal line 19 shorts in parallel the signal terminals 14-2 of the dielectric elements 15 and temperature sensors 14 of each electrode unit 12 located in the same column group and connects them to the adapter 20.

[0120] The first grounding switch 25-1 and the second grounding switch 25-2 on the adapter 20 are electrically connected to the first grounding wire 18-1 and the second grounding wire 18-2 of the electrode plate 10H respectively through the first connector 40, and the third grounding switch 25-3 and the fourth grounding switch 25-4 are in an idle and disconnected state. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 on the adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5 respectively via the first connector 40.

[0121] The tumor electric field therapy system formed by the electrode sheet 10H, the adapter 20, and the electric field generator 30 operates in the same way as the previous tumor electric field therapy system 100, with all grounding switches 25 disconnected and all bidirectional switching switches 26 input terminals 2When the acquisition terminal 1 is turned on and the acquisition terminal 1 is turned off, all dual-purpose signal lines 19 and AC signal lines 28 are connected, and all electrode units 12 are connected to AC signals; when the acquisition terminal 1 of all bidirectional switching switches 26 is turned on and the input terminal 2 is turned off, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25 in sequence. Among them, no operation is required for the grounding switch 25 in the idle and disconnected state.

[0122] Referring to FIG16, the electrode sheet 10J of the tenth embodiment is provided with 9 electrode units 12. In terms of electrical connection, the flexible circuit board 11J of the electrode sheet 10J arranges these 9 electrode units 12 in three rows and three columns, with 3 electrode units 12 in each row. The electrode plate 10J includes three grounding wires 18 and three dual-purpose signal lines 19. Each grounding wire 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the corresponding row group. Each dual-purpose signal line 19 is short-circuited to the dielectric element 15 of each electrode unit 12 in the corresponding column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals. The three grounding wires 18 of the electrode plate 10J are the first grounding wire 18-1, the second grounding wire 18-2, and the third grounding wire 18-3. In the three rows of the electrode plate 10J, the first row group includes electrode units 12-1 to 12-3, the second row group includes electrode units 12-4 to 12-6, and the third row group includes electrode units 12-7 to 12-9. Specifically, the first grounding wire 18-1 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-1 to electrode unit 12-3 in the first row group; the second grounding wire 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-4 to electrode unit 12-6 in the second row group; and the third grounding wire 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-7 to electrode unit 12-9 in the third row group. In short, each grounding wire 18 short-circuits and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group.

[0123] The three dual-purpose signal lines 19 of the electrode sheet 10J include the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, and the third dual-purpose signal line 19-3. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode unit 12-1, electrode unit 12-4, and electrode unit 12-7) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the electrode units 12-2, 12-5, and 12-6. (Instruction manual page 28 / 41, 32 CN 121288197 A)Each of the three electrode units 12 (12-8) has a dielectric element 15 and a signal terminal 14-2 of its respective temperature sensor 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric element 15 and the signal terminal 14-2 of the respective temperature sensor 14 of each of the three electrode units 12 (12-3, 12-6, and 12-9). In short, each dual-purpose signal line 19 short-circuits the dielectric element 15 and the signal terminal 14-2 of the respective temperature sensor 14 of each electrode unit 12 located in the same column group and connects them to the adapter 20.

[0124] The first grounding switch 25-1, the second grounding switch 25-2, and the third grounding switch 25-3 of the adapter 20 are electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, and the third grounding wire 18-3 respectively through the first connector 40J, and the fourth grounding switch 25-4 is in an idle and disconnected state. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, and the third bidirectional switching switch 26-3 of the adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, and the third dual-purpose signal line 19-3 respectively through the first connector 40J. The fourth bidirectional switching switch 26-4 and the fifth bidirectional switching switch 26-5 are both in an idle and disconnected state.

[0125] The working mode of the tumor electric field therapy system formed by the electrode sheet 10J, the adapter 20, and the electric field generator 30 is the same as that of the aforementioned tumor electric field therapy system 100. When all grounding switches 25 are disconnected and the input terminals 2 of all bidirectional switching switches 26 are turned on and the acquisition terminals 1 are disconnected, all dual-purpose signal lines 19 are connected to the AC signal line 28, and all electrode units 12 are connected to the AC signal. When the acquisition terminals 1 of all bidirectional switching switches 26 are turned on and the input terminals 2 are disconnected, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25. Among them, no operation is required for the grounding switch 25 and the bidirectional switching switch 26 which are in the idle and disconnected state.

[0126] In the tumor electric field therapy system of this application, the flexible circuit boards (11, 11A, 11B, 11C, 10D, 10E, 10F, 10G, 10H, 10J) of each electrode sheet (10, 10A, 10B, 10C, 10D, 10E, 10F, 10G, 10H, 10J) are divided into multiple rows and columns for their electrode units 12 in terms of electrical connection. The grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row is electrically connected to the same grounding wire 18. The dielectric element 15 and the signal terminal 14-2 of the temperature sensor 14 of each electrode unit 12 in the same column are short-circuited and then electrically connected to the same dual-purpose signal line 19. The adapter 20 is provided with multiple grounding switches 25 and multiple bidirectional switching switches 26.The grounding wires 18 of each electrode piece (10, 10A, 10B, 10C, 10D, 10E, 10F, 10G, 10H, 10J) are electrically connected to the corresponding grounding switch 25, and the dual-purpose signal lines 19 are electrically connected to the corresponding bidirectional switching switches 26. The number of grounding switches 25 is greater than or equal to the number of grounding wires 18, and the number of bidirectional switching switches 26 is greater than or equal to the number of dual-purpose signal lines 19. Therefore, the adapter 20 can adapt to various electrode pieces (10, 10A, 10B, 10C, 10D, 10E, 10F, 10G, 10H, 10J), and includes grounding switches 25 in an idle / disconnected state and / or bidirectional switching switches 26 in an idle / disconnected state.

[0127] This application also provides some temperature detection methods and AC signal application control methods, which are described below using electrode piece 10 as an example.

[0128] This application provides an electrode temperature detection method, applied to the electrode 10 or the tumor electric field therapy system 100 described above, as shown in FIG17, which includes the following steps:

[0129] Step 210: Control each bidirectional switching switch 26 electrically connected to each electrode unit 12 of the electrode 10 to disconnect the AC signal applied to the dielectric element 15 of each electrode unit 12 of the electrode 10, and simultaneously connect the DC signal applied to the signal terminal 14-2 of the temperature sensor 14 of each electrode unit 12 of the electrode 10;

[0130] Step 220: Sequentially turn on each grounding switch 25 electrically connected to the ground terminal 14-1 of the temperature sensor 14 of each electrode unit 12 of the electrode 10 in a time sequence to obtain the temperature detection signal of the temperature sensor 14 of each electrode unit 12 of the electrode 10.

[0131] Step 210 specifically involves: controlling the bidirectional switching switch 26 electrically connected to each electrode unit 12 of the electrode sheet 10 to switch from the end electrically connected to the AC signal to the end electrically connected to the DC signal, that is, controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch from its input terminal 2 to its acquisition terminal 1; or

[0132] controlling the bidirectional switching switch 26 electrically connected to each electrode unit 12 of the electrode sheet 10 to switch the dielectric element 15 of each electrode unit 12 of the electrode sheet 10 from the on state to the off state, and at the same time switching the signal terminal 14-2 of the temperature sensor 14 of each electrode unit 12 of the electrode sheet 10 from the off state to the on state.

[0133] The electrode temperature detection method of this application can quickly and accurately obtain the temperature of all electrode units of the electrode sheet; and can determine whether the temperature sensors of the electrode sheet are faulty, abnormal, or whether the electrode sheet is qualified and needs to be replaced based on the obtained temperature detection signals of all temperature sensors of the electrode sheet; it can also be used to detect the temperature of each electrode unit of the electrode sheet.When the temperature sensor is normal, the temperature detection signals of all temperature sensors of the electrode sheet are used to determine whether each electrode unit of the electrode sheet is overheated, and then the AC signal applied to the electrode sheet or each electrode unit of the electrode sheet is controlled; the electrode sheet type can also be identified when the temperature detection signals of each temperature sensor of the electrode sheet are normal.

[0134] Referring to FIG18, the embodiment of this application also provides an AC signal application control method for tumor electric field therapy, which includes the above steps 210 and 220, and after step 220, it further includes:

[0135] Step 260: When it is determined that the electrode sheet 10 does not need to be replaced, the AC signal applied to each electrode unit 12 of the electrode sheet 10 is controlled or adjusted according to the temperature detection signals of the temperature sensors 14 of each electrode unit 12 of the electrode sheet 10.

[0136] Step 260 further includes controlling or adjusting the AC signal applied to each electrode unit 12 of the electrode sheet 10:

[0137] Step 261: When the temperature detection signals of each electrode unit 12 of the electrode sheet 10 are not exceeded by a preset temperature threshold, continue to apply AC signals to each electrode unit 12 of the electrode sheet 10; or

[0138] Step 262: When there is a temperature detection signal in all the temperature detection signals of the electrode units 12 of the electrode sheet 10 that exceeds the preset temperature threshold, stop applying AC signals to the electrode units 12 of the electrode sheet 10.

[0139] The step 262 of stopping applying AC signals to the electrode units 12 of the electrode sheet 10 includes stopping applying AC signals to all electrode units 12 of the electrode sheet 10, stopping applying AC signals to the electrode units 12 in the electrode sheet 10 whose temperature detection signals exceed the preset temperature threshold, and stopping applying AC signals to all electrode units 12 in the column where the temperature detection signals of the electrode units 12 in the electrode sheet 10 exceed the preset temperature threshold.

[0140] When the application of AC signals to electrode units 12 in electrode sheet 10 where the temperature detection signal exceeds the preset temperature threshold is stopped, AC signals are continued to be applied to electrode units 12 in electrode sheet 10 where the temperature detection signal does not exceed the preset temperature threshold.

[0141] When the application of AC signals to all electrode units 12 in the column where the temperature detection signal exceeds the preset temperature threshold is stopped, AC signals are continued to be applied to all electrode units 12 in electrode sheet 10 where the temperature detection signal does not exceed the preset temperature threshold and are in a different column from the electrode units 12 where the temperature detection signal exceeds the preset temperature threshold.

[0142] The process of continuing to apply AC signals to electrode sheet 10 in step 261 is specifically as follows:

[0143] Step 263: When the temperature detection signal is much lower than the preset temperature threshold, the AC signals applied to each electrode unit 10 are increased.The AC signal is applied to each electrode unit 12 of the electrode sheet 10 in a manner that maintains the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode sheet 10; or

[0144] Step 264: When the temperature detection signal approaches the preset temperature threshold, the AC signal is applied to each electrode unit 12 of the electrode sheet 10 in a manner that maintains the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode sheet 10; or the AC signal is applied to each electrode unit 12 of the electrode sheet 10 in a manner that reduces the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode sheet 10.

[0145] Referring to FIG19, this application also provides a signal control method for tumor electric field therapy, used for the above-mentioned electrode sheet 10. The method includes:

[0146] Step 310: Combining control of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the corresponding electrode sheet 10 to apply an AC signal to each electrode unit 12 of the electrode sheet 10 and executing step 320;

[0147] Step 320: Combining control of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to collect temperature detection signals of each electrode unit of the electrode sheet 10 in a row and executing step 330;

[0148] Step 330: Determining the combination control mode of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the electrode sheet 10 according to the collected temperature detection signals and executing step 340;

[0149] Step 340: Controlling the working state of each electrode unit 12 of the electrode sheet 10 according to the determined combination control mode of the grounding switch 25 and the bidirectional switching switch 26.

[0150] The working states of each electrode unit 12 of the electrode sheet 10 in step 340 include: stopping the application of AC signals and continuing to acquire temperature detection signals, and stopping the acquisition of temperature detection signals and continuing to apply AC signals. Continuing to apply AC signals includes applying AC signals by increasing the voltage or current amplitude of the currently applied AC signal, applying AC signals by maintaining the voltage or current amplitude of the currently applied AC signal unchanged, and applying AC signals by decreasing the voltage or current amplitude of the currently applied AC signal.

[0151] The working state of each electrode unit 12 of the electrode sheet 10 is determined by the temperature detection signals it acquires. Each electrode unit 12 of the electrode sheet 10 is divided into different regions, and each electrode unit 12 in each region can be cyclically switched between applying AC signals and acquiring temperature detection signals through a combination of grounding switch 25 and bidirectional switching switch 26.

[0152] This application embodiment provides another method for detecting the temperature of electrode pads in a tumor electric field therapy system 100. Referring to FIG20, the temperature detection method includes:

[0153] Step 510: Disconnect the input of AC power signal to the electrode pad 10, perform combined control of multiple grounding switches 25 and multiple bidirectional switching switches 26, and acquire the temperature detection signal of the temperature sensor 14 of the electrode pad 10 corresponding to each combination;

[0154] Step 520: Sample and convert the temperature detection signal detected by each temperature sensor 14 in the electrode pad 10 to obtain a digital temperature signal;

[0155] Step 530: Transmit the digital temperature signal to the electric field generator 30 of the tumor electric field therapy system 100 so that the electric field generator 30 can determine the temperature at the corresponding electrode unit 12 according to the digital temperature signal.

[0156] In step 510, “combined control of multiple grounding switches 25 and multiple bidirectional switching switches 26” specifically includes:

[0157] Step 511: Place all bidirectional switching switches 26 at the acquisition end 1 to conduct the electrical connection between the signal terminals 14-2 of each temperature sensor 14 of all electrode units 12 and the corresponding analog-to-digital converter 23;

[0158] Step 512: Sequentially close one of the multiple grounding switches 25 individually to collect the temperature detection signals detected by the temperature sensors 14 of each electrode unit 12 in the corresponding row group.

[0159] In step 512, sequentially closing one of the multiple grounding switches 25 individually allows the detection channel of the analog-to-digital converter 23 to be electrically connected to each temperature sensor 14 in the row group corresponding to the closed grounding switch 25 to be turned on.

[0160] Thus, the temperature detection signals of each temperature sensor 14 in each row group can be obtained sequentially, and then processed by the adapter 20 or the electric field generator 30 through the specification page 31 / 41 35 CN 121288197 A to obtain the temperature corresponding to all electrode units 12 on the electrode sheet 10; thereby making the temperature detection of the patient's body surface more comprehensive and accurate.

[0161] For the tumor electric field therapy system 100 of this application embodiment, temperature detection can also be performed on individual electrode units 12 as needed. The specific process of temperature detection for a certain electrode unit 12 of the electrode sheet 10 is as follows: disconnect the input of the AC signal, place the bidirectional switching switch 26 corresponding to the column group where the electrode unit 12 that needs to be measured individually is located at the acquisition end 1, and place the remaining bidirectional switching switches 26 at the input end 2; at the same time, turn on and ground the grounding switch 25 corresponding to the row group where the electrode unit 12 that needs to be measured individually is located, and turn off all the remaining grounding switches 25. Therefore, the temperature detection signal of the temperature sensor 14 in the electrode unit 12 that requires separate temperature measurement can be sampled to obtain the temperature of the electrode unit 12.For example, if the electrode unit 12 requiring individual temperature measurement is electrode unit 12-1, then the corresponding AC signal switch 35 of the electric field generator 30 is turned off, and the first bidirectional switch 26-1 corresponding to electrode unit 12-1 is placed at the acquisition terminal 1. All other bidirectional switches (second bidirectional switch 26-2, second bidirectional switch 26-3, third bidirectional switch 26-3, and fourth bidirectional switch 26-4) are placed at the input terminal 2. Simultaneously, the first grounding switch 25-1 corresponding to electrode unit 12-1 is closed and grounded, and all remaining grounding switches (second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4) are turned off. Thus, the temperature of electrode unit 12-1 can be detected.

[0162] This application embodiment also provides another method for applying an alternating current signal for tumor electric field therapy, applied to the tumor electric field therapy system 100 described above. Referring to FIG21, the method for applying the alternating current signal includes:

[0163] Step 610: Determine the area where the electrode unit 12 in the electrode sheet 10 to which the alternating current signal needs to be applied is located;

[0164] Step 611: Combine and control multiple grounding switches 25 and multiple bidirectional switching switches 26 electrically connected to the electrode sheet 10 to apply the alternating current signal.

[0165] Step 611, “combining control of multiple grounding switches 25 and multiple bidirectional switching switches 26 electrically connected to electrode plate 10”, specifically includes:

[0166] Step 612: Disconnecting all grounding switches 25 electrically connected to electrode plate 10;

[0167] Step 613: Determining the column group where the electrode unit 12 that needs to be applied AC signal is located, based on the area where the electrode unit 12 that needs to be applied AC signal is located;

[0168] Step 614: Determining the bidirectional switching switch 26 electrically connected to the electrode unit 12 in these column groups, based on the column group where the electrode unit 12 that needs to be applied AC signal is located;

[0169] In step 610: Dividing each of the four adjacent electrode units 12 in electrode plate 10 into a region, the four electrode units 12 in each region correspond to a column group, and connected to a dual-purpose signal line 19 corresponding to the same bidirectional switching switch 26.

[0170] Step 615: Control the bidirectional switching switch 26 electrically connected to the electrode unit 12 that needs to apply an AC signal to connect the electrode unit 12 that needs to apply an AC signal to the AC signal line 28 to apply an AC signal; at the same time, control the remaining bidirectional switching switches 26 to disconnect the electrical connection between each electrode unit 12 in the area where no AC signal needs to be applied and the AC signal line 28, thereby stopping the application of AC signals.

[0171] In step 615, "connect the electrode unit that needs to apply an AC signal to the AC signal line 28 to apply an AC signal and disconnect the electrical connection between the electrode unit 12 in the area where no AC signal needs to be applied and the AC signal line 28".The "stop applying AC signal" is achieved by placing the bidirectional switching switch 26 electrically connected to the electrode unit 12 in the column group corresponding to the area where the AC signal is to be applied in the electrode sheet 10 at its input terminal 2, and placing all the bidirectional switching switches 26 electrically connected to the electrode unit 12 in the remaining column groups at the acquisition terminal 1.

[0172] The first controller 22 or electric field generator 30 in the adapter 20 of the tumor electric field therapy system 100 of this application embodiment is provided with a preset quantity threshold, a first preset temperature t1, a second preset temperature t2 and a preset temperature threshold t0, wherein the preset temperature t1 is lower than the second preset temperature t2, and the second preset temperature t2 is lower than the preset temperature threshold t0.

[0173] This application embodiment also provides an AC signal application method based on temperature detection signal for the above-mentioned tumor electric field therapy system 100. Please refer to FIG22. The application method includes:

[0174] Step 710: Start the tumor electric field therapy system 100;

[0175] Step 711: Combine the control of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the corresponding electrode plate 10 to apply an AC signal to each electrode unit 12 of the electrode plate 10;

[0176] Step 712: Combine the control of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the electrode plate 10 to obtain the temperature of each electrode unit 12 of the electrode plate 10;

[0177] Step 713: Determine whether there is an electrode unit 12 with a temperature exceeding a first preset temperature t1. If there is no electrode unit 12 with a temperature exceeding the first preset temperature t1, proceed to step 714. If there is an electrode unit 12 with a temperature exceeding the first preset temperature t1, proceed to step 715;

[0178] Step 714: Continue to apply an AC signal to each electrode unit 12 of the electrode plate 10 by increasing the voltage or current amplitude of the currently applied AC signal and return to step 712;

[0179] Step 715: Determine if there is an electrode unit 12 with a temperature exceeding the second preset temperature t2; if there is no electrode unit 12 with a temperature exceeding the second preset temperature t2, proceed to step 716; if there is an electrode unit 12 with a temperature exceeding the second preset temperature t2, proceed to step 717;

[0180] Step 716: Continue to apply AC signals to each electrode unit 12 of the electrode sheet 10 while maintaining the voltage or current amplitude of the currently applied AC signal unchanged, and return to step 712;

[0181] Step 717: Determine if there is an electrode unit 12 with a temperature exceeding the preset temperature threshold t0; if there is no electrode unit 12 with a temperature exceeding the preset temperature threshold t0, proceed to step 718; if there is an electrode unit with a temperature exceeding the preset temperature threshold t0, proceed to step 719;

[0182] Step 718: Continue applying AC signals to all electrode units 12 of the electrode sheet 10 by reducing the voltage or current amplitude of the currently applied AC signal and return to step 712;

[0183] Step 719: Determine the number of overheated regions and execute step 720, wherein the overheated region is the region containing electrode units whose temperature exceeds the preset temperature threshold t0, and the non-overheated region is the region where the temperature of all electrode units does not exceed the preset temperature threshold t0;

[0184] Step 720: Determine whether the number of overheated regions exceeds the preset number threshold. If the number of overheated regions exceeds the preset number threshold, execute step 721; if the number of overheated regions does not exceed the preset number threshold, execute step 724;

[0185] Step 721: Stop applying AC signals to each electrode unit 12 of the electrode sheet 10 and execute step 722;

[0186] Step 722: Combine the control of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the electrode plate 10 to obtain the temperature of each electrode unit 12 of the electrode plate 10 and execute step 723;

[0187] Step 723: Determine whether there is an electrode unit 12 with a temperature exceeding the first preset temperature t1. If there is no electrode unit 12 with a temperature exceeding the first preset temperature t1 in the electrode plate 10, return to step 711. If there is an electrode unit 12 with a temperature exceeding the first preset temperature t1 in the electrode plate 10, return to step 722;

[0188] Step 724: Distinguish between the over-temperature region and the non-over-temperature region based on whether there is an electrode unit 12 with a temperature exceeding the preset temperature threshold t0. If the region is an over-temperature region, execute step 725. If the region is a non-over-temperature region, execute step 726;

[0189] Step 725: Stop applying AC power signals to each electrode unit 12 in the over-temperature region and execute step 731;

[0190] Step 726: Determine whether the temperature of each electrode unit 12 in the non-overheated area does not exceed the first preset temperature t1. If the temperature of each electrode unit 12 in the non-overheated area does not exceed the first preset temperature t1, execute step 727. If the temperature of each electrode unit 12 in the non-overheated area exceeds the first preset temperature t1, execute step 728.

[0191] Step 727: Continue to apply an AC signal to each electrode unit 12 in the non-overheated area of ​​the electrode sheet 10 by increasing the voltage or current amplitude of the currently applied AC signal and execute step 731.

[0192] Step 728: Determine whether the temperature of each electrode unit 12 in the non-overheated area does not exceed the second preset temperature t2. If the temperature of each electrode unit 12 in the non-overheated area does not exceed the second preset temperature t2, execute step 729. If the temperature of each electrode unit 12 in the non-overheated area exceeds the second preset temperature t2, execute step 730.

[0193] Step 729: Continue applying AC signals to each electrode unit 12 in the non-overheated region of the electrode sheet 10 while maintaining the voltage or current amplitude of the currently applied AC signal unchanged, and execute step 731;

[0194] Step 730: Continue applying AC signals to each electrode unit 12 in the non-overheated region of the electrode sheet 10 while reducing the voltage or current amplitude of the currently applied AC signal, and execute step 731;

[0195] Step 731: Combine the control of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to reacquire the temperature of each electrode unit 12 of the electrode sheet 10 and select to execute step 732 or step 734. The temperature of each electrode unit 12 of the electrode sheet 10 includes the temperature of each electrode unit 12 in the overheated region and the temperature of each electrode unit 12 in the non-overheated region;

[0196] Step 732: Determine whether the temperature of each electrode unit 12 in the overheated area does not exceed the first preset temperature t1. If the temperature of each electrode unit 12 in the overheated area does not exceed the first preset temperature t1, execute step 733. If there is a temperature in each electrode unit 12 in the overheated area that exceeds the first preset temperature t1, return to step 731.

[0197] Step 733: Redetermine the area as an overheated area and execute step 734.

[0198] Step 734: Determine whether the temperature of each electrode unit 12 in the obtained overheated area does not exceed the first preset temperature t1. If the temperature of each electrode unit 12 in the overheated area does not exceed the first preset temperature t1, execute step 735. If there is a temperature in each electrode unit 12 in the overheated area that exceeds the first preset temperature t1, execute step 736.

[0199] Step 735: Continue to apply an AC signal to each electrode unit 12 in the overheated area by increasing the voltage or current amplitude of the currently applied AC signal and return to step 712.

[0200] Step 736: Determine whether the temperature of each electrode unit 12 in the obtained non-overheated area does not exceed the second preset temperature t2. If the temperature of each electrode unit 12 in the non-overheated area does not exceed the second preset temperature t2, execute step 737. If there is a temperature in each electrode unit 12 in the non-overheated area that exceeds the second preset temperature t2, execute step 738.

[0201] Step 737: Continue to apply AC signals to each electrode unit 12 in the non-overheated area while keeping the voltage or current amplitude of the currently applied AC signal unchanged, and return to step 712.

[0202] Step 738: Determine whether the temperature of each electrode unit 12 in the obtained non-overheated area does not exceed the preset temperature threshold t0. If the temperature of each electrode unit 12 in the non-overheated area does not exceed the preset temperature threshold t0, execute step 739. If there is a temperature in each electrode unit 12 in the non-overheated area that exceeds the preset temperature threshold t0, return to step 719.

[0203] Step 739: Continue to apply AC signals to each electrode unit 12 of the non-overheated area in a manner that reduces the voltage or current amplitude of the currently applied AC signal and return to step 712.

[0204] Referring to FIG22, the process of combining the control of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the corresponding electrode plate 10 in step 711 to apply AC signals to each electrode unit 12 of the electrode plate is specifically as follows:

[0205] Disconnect all grounding switches 25 electrically connected to the corresponding electrode plate 10, and simultaneously switch all bidirectional switching switches 26 electrically connected to the corresponding electrode plate 10 to the end that applies AC signals to each electrode unit 12; or

[0206] Disconnect all grounding switches 25 electrically connected to the corresponding electrode plate 10, and simultaneously switch all bidirectional switching switches 26 electrically connected to the corresponding electrode plate 10 to the end that connects each electrode unit 12 to the AC signal line 28; or Specification 34 / 41 pages 38 CN 121288197 A

[0207] Disconnect all grounding switches 25 electrically connected to the corresponding electrode plate 10, and simultaneously switch all bidirectional switching switches 26 electrically connected to the corresponding electrode plate 10 to their respective input terminals 2.

[0208] The process of obtaining the temperature of each electrode unit 12 of the electrode plate 10 in steps 712, 722, and 731 is specifically as follows:

[0209] Control the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch all of its input terminals 2 that apply AC signals to each electrode unit 12 to its acquisition terminals 1, and sequentially close the grounding switches 25 electrically connected to the electrode units 12 of the electrode plate 10 to obtain the temperature of each electrode unit 12; or

[0210] Control the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch all of its input terminals 2 that apply AC signals to each electrode unit 12 to its acquisition terminals 1, and sequentially close the grounding switches 25 electrically connected to the electrode units 12 of the electrode plate 10 to obtain the temperature of each electrode unit 12; or

[0211] Control the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch the electrode plate 10 from its input terminals 2 that apply AC signals to each electrode unit 12 to its acquisition terminals 1, and sequentially close the grounding switches 25 electrically connected to the electrode units 12 of the electrode plate 10 to obtain the temperature of each electrode unit 12; or

[0211] Control the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch the electrode plate 10 from its input terminals 2 that apply AC signals to each electrode unit 12 to its acquisition terminals 1, and sequentially close the grounding switches 25 electrically connected to the electrode units 12 of the electrode plate 10 to obtain the temperature of each electrode unit 12 of the electrode plate 10. Signal line 28 is electrically connected to switch each electrode unit 12 to the corresponding analog-to-digital converter 23, and the grounding switch 25 electrically connected to each electrode unit 12 of the electrode sheet 10 is closed sequentially in a time-sharing manner to obtain the temperature of each electrode unit 12 of the electrode sheet 10; or

[0212] the bidirectional switching switch 26 electrically connected to the electrode sheet 10 is controlled to switch each electrode unit 12 of the electrode sheet 10 from transmitting AC signals to transmitting DC signals or temperature detection signals, and the grounding switch 25 electrically connected to each electrode unit 12 of the electrode sheet 10 is closed sequentially in a time-sharing manner to obtain the temperature of each electrode unit 12 of the electrode sheet 10.

[0213] The first preset temperature in steps 713, 723, 726, 732, and 734 is 40℃-40.3℃, preferably 40.2℃. The second preset temperature in steps 715, 728, and 736 is 40.4℃ to 40.6℃, preferably 40.5℃; the preset temperature threshold in steps 717 and 738 is 41℃ to 41.5℃, preferably 41℃; the preset quantity threshold in step 720 is preferably 2.

[0214] The process of continuing to apply AC signals in steps 714, 716, 718, 727, 729, 730, 735, 737, and 739 is specifically as follows:

[0215] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 to which AC signals need to be continuously applied, and simultaneously control the bidirectional switching switch 26 electrically connected to the electrode unit 12 to which AC signals need to be continuously applied to conduct the AC signal transmission path electrically connected to the electrode unit 12 to which AC signals need to be continuously applied to continue applying AC signals to the electrode unit 12; or

[0216] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 to which AC signals need to be continuously applied, and simultaneously control the bidirectional switching switch 26 electrically connected to the electrode unit 12 to which AC signals need to be continuously applied to switch from its respective acquisition terminal 1 to its respective input terminal 2 to continue applying AC signals to the electrode unit 12 to which AC signals need to be continuously applied to continue applying AC signals; or

[0217] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 that needs to continue applying AC signals, and simultaneously control the bidirectional switching switch 26 electrically connected to the electrode unit 12 that needs to continue applying AC signals to both of its input terminals 2 to the AC signal line 28, so as to continue applying AC signals to the electrode unit 12 that needs to continue applying AC signals; or

[0218] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 that needs to continue applying AC signals, and simultaneously control the bidirectional switching switch 26 electrically connected to the electrode unit 12 that needs to continue applying AC signals to both of its input terminals 2 to close and the acquisition terminal 1 to open, so as to continue applying AC signals to the electrode unit 12 that needs to continue applying AC signals; or

[0219] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 that needs to continue applying AC signals, and simultaneously control the bidirectional switching switch 26 electrically connected to the electrode unit 12 that needs to continue applying AC signals to switch the electrode unit 12 from transmitting temperature detection signals to applying AC signals. Instruction manual, pages 35 / 41, 39 CN 121288197 A

[0220] The increase in the voltage or current amplitude of the currently applied AC signal in steps 714, 727, and 735 hasThe body is to boost the voltage of the currently applied AC signal by increasing the DC voltage amplitude by 0.03V per second.

[0221] The method of continuing to apply the AC signal by reducing the voltage or current amplitude of the currently applied AC signal in steps 718, 730 and 739 is to continue to apply the AC signal by reducing the voltage or current amplitude of the currently applied AC signal by 5V for 3 minutes.

[0222] The process of stopping the application of AC signals to each electrode unit 12 of the electrode plate 10 in step 721 specifically includes:

[0223] Controlling the bidirectional switching switch 26 electrically connected to the electrode plate 10 to disconnect the electrical connection between each electrode unit 12 of the electrode plate 10 and the AC signal line 28; or

[0224] Controlling the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch all of its ends that apply AC signals to each electrode unit 12 to its ends that collect temperature data from each electrode unit 12; or

[0225] Controlling the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch all of its input ends 2 that apply AC signals to each electrode unit 12 to its acquisition ends 1; or

[0226] Controlling the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch the electrode plate 10 from an electrical connection between each electrode unit 12 and the AC signal line 28 to an electrical connection between each electrode unit 12 and the corresponding analog-to-digital converter 23; or

[0227] The bidirectional switching switch 26, which is electrically connected to the electrode plate 10, switches each electrode unit 12 of the electrode plate 10 from transmitting AC signals to transmitting DC signals or temperature detection signals.

[0228] The process of stopping the application of AC signals to each electrode unit 12 in the over-temperature region described in step 725 is specifically as follows:

[0229] The bidirectional switching switch 26, which is electrically connected to each electrode unit 12 in the over-temperature region, disconnects the electrical connection between each electrode unit 12 in the over-temperature region and the AC signal line 28; or

[0230] The bidirectional switching switch 26, which is electrically connected to each electrode unit 12 in the over-temperature region, switches from the end where it applies AC signals to each electrode unit 12 in the over-temperature region to the end where it performs temperature acquisition; or

[0231] The bidirectional switching switch 26, which is electrically connected to each electrode unit 12 in the over-temperature region, switches from the input end 2 where it applies AC signals to each electrode unit 12 in the over-temperature region to its acquisition end 1; or

[0232] The bidirectional switching switch 26, which controls the electrical connection of each electrode unit 12 in the over-temperature zone, switches each electrode unit 12 in the over-temperature zone from being electrically connected to the AC signal line 28 to being electrically connected to the corresponding analog-to-digital converter 23; or

[0233] the bidirectional switching switch 26, which controls the electrical connection of each electrode unit 12 in the over-temperature zone, switches each electrode unit 12 in the over-temperature zone from transmitting AC signals to transmitting DC signals or temperature detection signals.

[0234] In the above application method, the tumor electric field therapy system 100 includes at least two pairs of electrode plates 10 to alternately apply alternating electric fields with different directions. Each electrode plate 10 can alternately switch between applying an AC signal and transmitting a temperature detection signal. The time periods for applying an AC signal and applying a DC signal for temperature acquisition in the electrode unit 12 of the same electrode plate 10 are staggered and do not overlap.

[0235] The first controller 22 or electric field generator 30 in the adapter 20 of the tumor electric field therapy system 100 of this application embodiment is further provided with a third preset temperature t3. The third preset temperature t3 is higher than the second preset temperature t2 but still lower than the preset temperature threshold t0. The third preset temperature t3 is closer to the preset temperature threshold t0 than the second preset temperature t2. This application embodiment also provides an AC signal control method based on temperature detection signals for the aforementioned tumor electric field therapy system. Referring to page 36 / 41 of the specification (CN 121288197 A 23), the AC signal control method includes:

[0236] Step 810: Activating the tumor electric field therapy system 100;

[0237] Step 811: Combining the control of a grounding switch 25 and a bidirectional switching switch 26 electrically connected to the corresponding electrode pad 10 to apply an AC signal to each electrode unit 12 of the electrode pad 10;

[0238] Step 812: Combining the control of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the electrode pad 10 to obtain the temperature of each electrode unit 12 of the electrode pad 10;

[0239] Step 813: Determine if there is an electrode unit 12 with a temperature exceeding the first preset temperature t1. If there is no electrode unit 12 with a temperature exceeding the first preset temperature t1, proceed to step 814. If there is an electrode unit 12 with a temperature exceeding the first preset temperature t1, proceed to step 815.

[0240] Step 814: Continue to apply AC signals to each electrode unit 12 of the electrode sheet 10 by increasing the voltage or current amplitude of the currently applied AC signal and return to step 812.

[0241] Step 815: Determine if there is an electrode unit 12 with a temperature exceeding the second preset temperature t2. If there is no electrode unit 12 with a temperature exceeding the second preset temperature t2, proceed to step 816. If there is an electrode unit 12 with a temperature exceeding the second preset temperature t2, proceed to step 817.

[0242] Step 816: Continue to apply AC signals to each electrode unit 12 of the electrode sheet 10 by keeping the voltage or current amplitude of the currently applied AC signal unchanged and return to step 812.

[0243] Step 817: Determine whether there is an electrode unit 12 with a temperature exceeding the third preset temperature t3. If there is no electrode unit 12 with a temperature exceeding the third preset temperature t3, proceed to step 818; if there is an electrode unit with a temperature exceeding the third preset temperature t3, proceed to step 819;

[0244] Step 818: Continue applying AC signals to all electrode units 12 of electrode sheet 10 by reducing the voltage or current amplitude of the currently applied AC signal and return to step 812;

[0245] Step 819: Determine whether there are electrode units 12 with a temperature exceeding the preset temperature threshold t0. If there are no electrode units 12 with a temperature exceeding the preset temperature threshold t0, proceed to step 820; if there are electrode units with a temperature exceeding the preset temperature threshold t0, proceed to step 821;

[0246] Step 820: Continue applying AC signals to all electrode units 12 of electrode sheet 10 by reducing the voltage or current amplitude of the currently applied AC signal and return to step 812;

[0247] Step 821: Determine the number of overheated areas and proceed to step 822, wherein the overheated area is the area containing electrode units with a temperature exceeding the preset temperature threshold t0, and the non-overheated area is the area where the temperature of all electrode units within it does not exceed the preset temperature threshold t0;

[0248] Step 822: Determine whether the number of overheated areas exceeds a preset threshold. If the number of overheated areas exceeds the preset threshold, proceed to step 823. If the number of overheated areas does not exceed the preset threshold, proceed to step 826.

[0249] Step 823: Stop applying AC signals to each electrode unit 12 of the electrode sheet 10 and proceed to step 824.

[0250] Step 824: Combine the control of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to obtain the temperature of each electrode unit 12 of the electrode sheet 10 and proceed to step 825.

[0251] Step 825: Determine whether there is an electrode unit 12 with a temperature exceeding the first preset temperature t1. If there is no electrode unit 12 with a temperature exceeding the first preset temperature t1 in the electrode sheet 10, return to step 811. If there is an electrode unit 12 with a temperature exceeding the first preset temperature t1 in the electrode sheet 10, return to step 824.

[0252] Step 826: Distinguish between overheated and non-overheated regions based on whether there are electrode units 12 with temperatures exceeding the preset temperature threshold t0. If the region is an overheated region, proceed to step 827; if the region is a non-overheated region, proceed to step 828.

[0253] Step 827: Stop applying AC signals to each electrode unit 12 in the overheated region and proceed to step 835.

[0254] Step 828: Determine whether the temperatures of each electrode unit 12 in the non-overheated region do not exceed the first preset temperature t1. If the temperatures of each electrode unit 12 in the non-overheated region do not exceed the first preset temperature t1, proceed to step 829. If any electrode unit 12 in the non-overheated region has a temperature exceeding the first preset temperature t1, proceed to step 830.

[0255] Step 829: Continue applying AC signals to the electrode sheet by increasing the voltage or current amplitude of the currently applied AC signal.Step 835 is executed when an AC signal is applied to each electrode unit 12 in the non-overheated area;

[0256] Step 830: It is determined whether the temperature of each electrode unit 12 in the non-overheated area does not exceed the second preset temperature t2. When the temperature of each electrode unit 12 in the non-overheated area does not exceed the second preset temperature t2, step 831 is executed. When there is a temperature in each electrode unit 12 in the non-overheated area that exceeds the second preset temperature t2, step 832 is executed;

[0257] Step 831: An AC signal is continued to be applied to each electrode unit 12 in the non-overheated area of ​​the electrode sheet 10 while keeping the voltage or current amplitude of the currently applied AC signal unchanged, and step 835 is executed;

[0258] Step 832: Determine whether there are any electrode units 12 in the non-overheated area whose temperature exceeds the third preset temperature t3. If the temperature of all electrode units 12 in the non-overheated area does not exceed the third preset temperature t3, proceed to step 833. If there is a temperature in any electrode unit 12 in the non-overheated area that exceeds the third preset temperature t3, proceed to step 834.

[0259] Step 833: Continue to apply AC signals to each electrode unit 12 in the non-overheated area of ​​the electrode sheet 10 by reducing the voltage or current amplitude of the currently applied AC signal and proceed to step 835.

[0260] Step 834: Continue to apply AC signals to each electrode unit 12 in the non-overheated area of ​​the electrode sheet 10 by further reducing the voltage or current amplitude of the currently applied AC signal and proceed to step 835.

[0261] Step 835: Combine the control of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the electrode plate 10 to reacquire the temperature of each electrode unit 12 of the electrode plate 10 and select to execute step 836 or step 838. The temperature of each electrode unit 12 of the electrode plate 10 includes the temperature of each electrode unit 12 in the over-temperature region and the temperature of each electrode unit 12 in the non-over-temperature region;

[0262] Step 836: Determine whether the temperature of each electrode unit 12 in the over-temperature region does not exceed the first preset temperature t1. If the temperature of each electrode unit 12 in the over-temperature region does not exceed the first preset temperature t1, execute step 837. If there is a temperature in each electrode unit 12 in the over-temperature region that exceeds the first preset temperature t1, return to step 835;

[0263] Step 837: Redetermine the region as a non-over-temperature region and execute step 838;

[0264] Step 838: Determine whether the temperature of each electrode unit 12 in the obtained non-overheated area does not exceed the first preset temperature t1. If the temperature of each electrode unit 12 in the non-overheated area does not exceed the first preset temperature t1, proceed to step 839. If any of the electrode units 12 in the non-overheated area exceeds the first preset temperature t1, proceed to step 840.

[0265] Step 839: Continue applying AC signals to each electrode unit 12 in the non-overheated area by increasing the voltage or current amplitude of the currently applied AC signal and return to step 812;

[0266] Step 840: Determine whether the temperature of each electrode unit 12 in the non-overheated area does not exceed the second preset temperature t2. If the temperature of each electrode unit 12 in the non-overheated area does not exceed the second preset temperature t2, execute step 841. If there is a temperature in each electrode unit 12 in the non-overheated area that exceeds the second preset temperature t2, execute step 842;

[0267] Step 841: Continue applying AC signals to each electrode unit 12 in the non-overheated area while keeping the voltage or current amplitude of the currently applied AC signal unchanged and return to step 812;

[0268] Step 842: Determine whether the temperature of each electrode unit 12 in the non-overheated area does not exceed the third preset temperature t3. If the temperature of each electrode unit 12 in the non-overheated area does not exceed the third preset temperature t3, execute step 843. Instruction manual, pages 38 / 41, CN 121288197 A: When the temperature of each electrode unit 12 in the non-overheated area exceeds the third preset temperature t3, step 844 is executed;

[0269] Step 843: Continue to apply AC signals to each electrode unit 12 in the non-overheated area by reducing the voltage or current amplitude of the currently applied AC signal and return to step 812;

[0270] Step 844: Determine whether the temperature of each electrode unit 12 in the non-overheated area does not exceed the preset temperature threshold t0. When the temperature of each electrode unit 12 in the non-overheated area does not exceed the preset temperature threshold t0, step 845 is executed. When the temperature of each electrode unit 12 in the non-overheated area exceeds the preset temperature threshold t0, return to step 821;

[0271] Step 845: Continue applying AC signals to each electrode unit 12 in the non-overheated area by further reducing the voltage or current amplitude of the currently applied AC signal and return to step 812.

[0272] Specifically, the process of combining the control of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the corresponding electrode plate 10 in step 811 to apply AC signals to each electrode unit 12 of the electrode plate is as follows:

[0273] Disconnect all grounding switches 25 electrically connected to the corresponding electrode plate 10, and simultaneously switch all bidirectional switching switches 26 electrically connected to the corresponding electrode plate 10 to the end that applies AC signals to each electrode unit 12; or

[0274] Disconnect all grounding switches 25 electrically connected to the corresponding electrode plate 10, and simultaneously switch all bidirectional switching switches 26 electrically connected to the corresponding electrode plate 10 to the end that electrically connects each electrode unit 12 to the AC signal line 28; or

[0275] Disconnect all grounding switches 25 that are electrically connected to the corresponding electrode piece 10, and simultaneously switch all bidirectional switching switches 26 that are electrically connected to the corresponding electrode piece 10 to their respective input terminals 2.

[0276] The process of obtaining the temperature of each electrode unit 12 of the electrode plate 10 in steps 812, 824, and 835 is specifically as follows:

[0277] Control the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch all of its input terminals 2 that apply AC signals to each electrode unit 12 to its acquisition terminals 1, and sequentially close the grounding switches 25 electrically connected to the electrode units 12 of the electrode plate 10 to obtain the temperature of each electrode unit 12; or

[0278] Control the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch all of its input terminals 2 that apply AC signals to each electrode unit 12 to its acquisition terminals 1, and sequentially close the grounding switches 25 electrically connected to the electrode units 12 of the electrode plate 10 to obtain the temperature of each electrode unit 12; or

[0279] Control the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch the electrode plate 10 from its input terminals 2 that apply AC signals to each electrode unit 12 to its acquisition terminals 1, and sequentially close the grounding switches 25 electrically connected to the electrode units 12 of the electrode plate 10 to obtain the temperature of each electrode unit 12; or

[0279] Control the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch the electrode plate 10 from its input terminals 2 that apply AC signals to each electrode unit 12 to its acquisition terminals 1, and sequentially close the grounding switches 25 electrically connected to the electrode units 12 of the electrode plate 10 to obtain the temperature of each electrode unit 12 of the electrode plate 10. Signal line 28 is electrically connected to switch each electrode unit 12 to be electrically connected to the corresponding analog-to-digital converter 23, and the grounding switch 25 electrically connected to each electrode unit 12 of the electrode sheet 10 is closed in sequence at different times to obtain the temperature of each electrode unit 12 of the electrode sheet 10; or

[0280] the bidirectional switching switch 26 electrically connected to the electrode sheet 10 is controlled to switch each electrode unit 12 of the electrode sheet 10 from transmitting AC signal to transmitting DC signal or temperature detection signal, and the grounding switch 25 electrically connected to each electrode unit 12 of the electrode sheet 10 is closed in sequence at different times to obtain the temperature of each electrode unit 12 of the electrode sheet 10.

[0281] The first preset temperature in steps 813, 825, 828, 836, and 838 is 40℃-40.3℃, preferably 40.2℃. In steps 815, 830, and 840, the second preset temperature is 40.4℃ to 40.6℃, preferably 40.5℃; in steps 817, 832, and 842, the third preset temperature is 40.7℃ to 40.9℃, preferably 40.8℃; in steps 819 and 844, the preset temperature threshold is 41℃ to 41.5℃, preferably 41℃; in step 822, the preset quantity threshold is preferably 2.

[0282] The process of continuing to apply AC signal as described in steps 814, 816, 818, 820, 829, 831, 833, 834, 839, 841, 843, and 845 is specifically as follows:

[0283] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 that needs to continue applying AC signal, and simultaneously control the control of the control unit 12.CN 121288197 A A bidirectional switching switch 26 electrically connected to an electrode unit 12 that requires continued application of AC signal is used to conduct the AC signal transmission path electrically connected to the electrode unit 12 that requires continued application of AC signal, thereby continuing to apply AC signal to the electrode unit 12 that requires continued application of AC signal; or

[0284] a grounding switch 25 electrically connected to an electrode unit 12 that requires continued application of AC signal is disconnected, and simultaneously the bidirectional switching switch 26 electrically connected to the electrode unit 12 that requires continued application of AC signal is controlled to switch from its respective acquisition terminal 1 to its respective input terminal 2, thereby continuing to apply AC signal to the electrode unit 12 that requires continued application of AC signal; or

[0285] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 that needs to continue applying AC signals, and simultaneously control the bidirectional switching switch 26 electrically connected to the electrode unit 12 that needs to continue applying AC signals to both of its input terminals 2 to the AC signal line 28, so as to continue applying AC signals to the electrode unit 12 that needs to continue applying AC signals; or

[0286] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 that needs to continue applying AC signals, and simultaneously control the bidirectional switching switch 26 electrically connected to the electrode unit 12 that needs to continue applying AC signals to both of its input terminals 2 to close and the acquisition terminal 1 to open, so as to continue applying AC signals to the electrode unit 12 that needs to continue applying AC signals; or

[0287] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 that needs to continue applying AC signals, and simultaneously control the bidirectional switching switch 26 electrically connected to the electrode unit 12 that needs to continue applying AC signals to switch the electrode unit 12 from transmitting temperature detection signals to applying AC signals.

[0288] The method of increasing the voltage or current amplitude of the currently applied AC signal in steps 814, 829, and 839 specifically refers to boosting the voltage of the currently applied AC signal by an increment of 0.03V DC voltage amplitude per second before continuing to apply the AC signal.

[0289] The method of decreasing the voltage or current amplitude of the currently applied AC signal in steps 818, 820, 833, 834, 843, and 845 specifically refers to continuing to apply the AC signal by decreasing the voltage or current amplitude of the currently applied AC signal by 5V for 3 minutes.

[0290] The process of stopping the application of AC signals to each electrode unit 12 of the electrode plate 10 in step 823 specifically involves:

[0291] Controlling the bidirectional switching switch 26 electrically connected to the electrode plate 10 to disconnect the electrical connection between each electrode unit 12 of the electrode plate 10 and the AC signal line 28; or

[0292]

[0293] Control the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch all of its input terminals 2 that apply AC signals to each electrode unit 12 to its acquisition terminals 1; or

[0294] Control the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch all of its input terminals 2 that apply AC signals to each electrode unit 12 to its acquisition terminals 1; or

[0295] Control the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch the electrode plate 10 from being electrically connected to the AC signal line 28 to being electrically connected to the corresponding analog-to-digital converter 23; or

[0296] Control the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch each electrode unit 12 of the electrode plate 10 from transmitting AC signals to transmitting DC signals or temperature detection signals.

[0296] The process of stopping the application of AC signals to each electrode unit 12 in the over-temperature zone as described in step 827 is specifically as follows:

[0297] Controlling the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature zone to disconnect the electrical connection between each electrode unit 12 in the over-temperature zone and the AC signal line 28; or

[0298] Controlling the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature zone to switch all of its ends that apply AC signals to each electrode unit 12 in the over-temperature zone to its ends that perform temperature sampling; or

[0299] Controlling the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature zone to switch all of its input ends 2 that apply AC signals to each electrode unit 12 in the over-temperature zone to its sampling ends 1; or

[0300] The bidirectional switching switch 26, which controls the electrical connection of each electrode unit 12 in the overheated area, switches each electrode unit 12 in the overheated area from being electrically connected to the AC signal line 28 to being electrically connected to the corresponding analog-to-digital converter 23; or

[0301] the bidirectional switching switch 26, which controls the electrical connection of each electrode unit 12 in the overheated area, switches each electrode unit 12 in the overheated area from transmitting AC signals to transmitting DC signals or temperature detection signals.

[0302] When the tumor electric field therapy system 100 is in the standby state before starting work, no AC signal is applied to the electrode unit 12. The first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls the bidirectional switching switch 26 to switch to the acquisition terminal 1. The grounding switches 25 are turned on in sequence, and the analog-to-digital converter 23 receives the temperature detection signals of the temperature sensors 14 corresponding to each row of electrode units 12 in sequence.

[0303] When the first grounding switch 25-1 is turned on, all other grounding switches 25 are turned off, and all bidirectional switching switches 26 are placed at the acquisition terminal 1, the analog-to-digital converter 23 receives the temperature detection signal of the temperature sensor 14 corresponding to the electrode unit 12.

[0304] When the second grounding switch 25-2 is on, all other grounding switches 25 are off, and all bidirectional switching switches 26 are placed at the acquisition terminal 1, the analog-to-digital converter 23 receives the temperature detection signal of the temperature sensor 14 corresponding to the electrode unit 12;

[0305] When the third grounding switch 25-3 is on, all other grounding switches 25 are off, and all bidirectional switching switches 26 are placed at the acquisition terminal 1, the analog-to-digital converter 23 receives the temperature detection signal of the temperature sensor 14 corresponding to the electrode unit 12;

[0306] When the fourth grounding switch 25-4 is on, all other grounding switches 25 are off, and all bidirectional switching switches 26 are placed at the acquisition terminal 1, the analog-to-digital converter 23 receives the temperature detection signal of the temperature sensor 14 corresponding to the electrode unit 12.

[0307] The first controller 22 receives the temperature detection signal from the temperature sensor 14 corresponding to each electrode unit 12 through the analog-to-digital converter 23, and transmits it to the AC signal generator 34 of the electric field generator 30 through the first communication unit 27 and the second communication unit 33. Then, the second controller 32 controls or adjusts the AC signal applied to each electrode unit 12.

[0308] When the above methods are applied to the electrode sheets (10D, 10E, 10F, 10G and 10J) of other embodiments, since there are idle and disconnected grounding switches 25 and / or idle and disconnected bidirectional switching switches 26 on the adapter 20 that are not electrically connected to the corresponding electrode sheets (10D, 10E, 10F, 10G and 10J), the corresponding idle and disconnected grounding switches 25 and / or idle and disconnected bidirectional switching switches 26 do not need to be controlled.

[0309] Although the various operations are depicted in the accompanying drawings in a specific order, this should not be construed as requiring that these operations must be performed in the specific order shown or in chronological order, nor should it be construed as requiring that all the operations shown must be performed to obtain the desired result.

[0310] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this application, and not to limit them; although this application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein; and these modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this application, and they should all be covered within the scope of the claims and specification of this application. In particular, as long as there is no structural conflict, the various technical features mentioned in the various embodiments can be combined in any way. This application is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims. Specification 41 / 41 pages 45 CN 121288197 A Figure 1 Specification Drawings 1 / 19 pages 46 CNFigure 2, Figure 3, Appendix 2 / 19, Page 47, CN 121288197 A; Figure 4, Appendix 3 / 19, Page 48, CN 121288197 A; Figure 5, Appendix 4 / 19, Page 49, CN 121288197 A; Figure 6, Appendix 5 / 19, Page 50, CN 121288197 A; Figure 7, Appendix 6 / 19, Page 51, CN 121288197 A; Figure 8, Appendix 7 / 19, Page 52, CN 121288197 A; Figure 9, Appendix 8 / 19, Page 53, CN 121288197 A; Figure 10, Appendix 9 / 19, Page 54, CN 121288197 A; Figure 11, Appendix 10 / 19, Page 55, CN 121288197 A; Figure 12, Appendix 11 / 19, Page 56, CN 121288197 A CN 121288197 A Figure 13 Appendix to the Instruction Manual, Page 12 / 19, 57 CN 121288197 A Figure 14 Appendix to the Instruction Manual, Page 13 / 19, 58 CN 121288197 A Figure 15 Appendix to the Instruction Manual, Page 14 / 19, 59 CN 121288197 A Figure 16 Figure 17 Appendix to the Instruction Manual, Page 15 / 19, 60 CN 121288197 A Figure 18 Figure 19 Appendix to the Instruction Manual, Page 16 / 19, 61 CN 121288197 A Figure 20 Figure 21 Appendix to the Instruction Manual, Page 17 / 19, 62 CN 121288197 A Figure 22 Appendix to the Instruction Manual, Page 18 / 19, 63 CN 121288197 A Figure 23 Appendix to the Instruction Manual, Page 19 / 19, 64 CN 121288197 A Abstract The present invention provides an electric field generator, a tumor electric field therapy system, method for detecting temperatures and over-temperatures of electrode pads. The electric field generator is electrically connected with the electrode pads, eachelectrode pad comprises a flexible circuit board and a plurality of electrode units disposed on the flexible circuit board and arranged in a plurality of rows and columns in a circuit, each electrode unit is provided with a dielectric element and a temperature sensor, the flexible circuit board is provided with a plurality of grounding lines and a plurality of dual-purpose signal lines, each grounding line is respectively short-circuited with the grounding terminal of each temperature sensor in a corresponding row, and each dual-purpose signal line is respectively connected with the dielectric element of each electrode unit and the signal terminal of the temperature sensor of each electrode unit in a corresponding column. The electric field generator is provided with a plurality of grounding switches respectively connected in series with the respective grounding lines and a plurality of bidirectional change-over switches respectively connected in series with the respective dual-purposesignal lines; each dual-purpose signal line is selectively connected to an alternating current signal or a direct current signal via the corresponding bidirectional change-over switch in a switching manner, so as to cause the electrode units to switch between a first mode for applying the alternating current signal and a second mode for detecting temperatures.

Claims

1. An electric field generator, characterized in that: For providing alternating current signals to an electrode pad of a tumor electric field therapy system, the electrode pad includes a flexible circuit board with multiple grounding lines and multiple dual-purpose signal lines, and multiple electrode units disposed on the flexible circuit board. Each electrode unit has a dielectric element for applying alternating current signals and a temperature sensor for detecting temperature, having both a grounding terminal and a signal terminal. The signal terminal of the temperature sensor in each electrode unit is short-circuited to its dielectric element. The multiple electrode units are arranged in multiple rows and multiple columns. The grounding terminals of the temperature sensors of each electrode unit in the same row are short-circuited through the same grounding line. The grounding terminals of the temperature sensors of each electrode unit in different rows are connected in parallel through different grounding lines. The grounding terminals of the temperature sensors of each electrode unit in the same column are also short-circuited. The signal terminals of the dielectric element and the temperature sensor are shorted together by the same dual-purpose signal line. The signal terminals of the dielectric element and the temperature sensor of each electrode unit located in different columns are connected in parallel by different dual-purpose signal lines. The electric field generator is provided with multiple grounding switches and multiple bidirectional switching switches corresponding to the electrode sheet. Each grounding wire of the electrode sheet is grounded by a corresponding grounding switch. Each dual-purpose signal line is electrically connected to a corresponding bidirectional switching switch. Each dual-purpose signal line switches between receiving an AC signal in the first mode and receiving a DC signal in the second mode through the bidirectional switching switch connected in series with it. In the first mode, the electrode unit applies an AC signal through its dielectric element and in the second mode, it detects the temperature through its temperature sensor.

2. The electric field generator according to claim 1, characterized in that, The bidirectional switching switch is provided with an input terminal for receiving AC signals and a acquisition terminal for receiving DC signals. The bidirectional switching switch turns on its input terminal in the first mode and turns on its acquisition terminal in the second mode.

3. The electric field generator according to claim 1, characterized in that, The number of grounding switches is greater than or equal to the number of grounding wires, and / or the number of bidirectional switching switches is greater than or equal to the number of dual-purpose signal lines.

4. The electric field generator according to claim 3, characterized in that, The plurality of grounding switches include a grounding switch that is in an idle open state; and / or the plurality of bidirectional switching switches include a bidirectional switching switch that is in an idle open state.

5. The electric field generator according to claim 1, characterized in that, An analog-to-digital converter is provided, which has multiple detection channels. The acquisition terminal of each bidirectional switching switch is electrically connected to a corresponding detection channel. The analog-to-digital converter samples the temperature detection signals of each temperature sensor.

6. The electric field generator according to claim 5, characterized in that, An AC signal line is provided, and the input terminal of each of the bidirectional switching switches is electrically connected to the AC signal line.

7. The electric field generator according to claim 1, characterized in that, The electric field generator is configured to: combine and control each of the grounding switches and each of the bidirectional switching switches to (1) transmit AC signals to the dielectric elements of each of the electrode units through each of the dual-purpose signal lines in a first mode; and (2) transmit DC signals to the signal terminals of the temperature sensors of each of the electrode units through each of the dual-purpose signal lines or transmit temperature detection signals detected by the temperature sensors of each of the electrode units through each of the dual-purpose signal lines in a second mode.

8. The electric field generator according to claim 7, characterized in that, The electric field generator is also configured to determine the operating state of each electrode unit based on the temperature detection signals of each of the temperature sensors.

9. The electric field generator according to claim 8, characterized in that, The electric field generator has a preset temperature threshold and is further configured to: When none of the temperature detection signals exceed the preset temperature threshold, the grounding switches and bidirectional switching switches are controlled in combination to transmit AC signals to the dielectric elements of the electrode units through the dual-purpose signal lines. When a temperature detection signal exceeds the preset temperature threshold, the grounding switches and bidirectional switching switches are controlled in combination to stop the transmission of the AC signal.

10. The electric field generator according to claim 9, characterized in that, The electric field generator is also configured to: When all the temperature detection signals are much lower than the preset temperature threshold, the grounding switches and bidirectional switching switches are combined to transmit AC signals with increased intensity or constant intensity to the dielectric elements of each electrode unit through the dual-purpose signal lines. When a temperature detection signal approaches the preset temperature threshold, the grounding switches and bidirectional switching switches are controlled in combination to transmit AC signals with constant or reduced strength to the dielectric elements of each electrode unit through the dual-purpose signal lines.

11. The electric field generator according to claim 9, characterized in that, Stopping the transmission of the AC signal includes stopping the transmission of AC signals to the dielectric elements of all the electrode units and stopping the transmission of AC signals to each of the electrode units in the column group where the electrode unit exceeds the preset temperature threshold.

12. The electric field generator according to claim 1, characterized in that, The electric field generator has a first preset temperature and a preset temperature threshold, wherein the first preset temperature is less than the preset temperature threshold, and the electric field generator is configured to: compare each of the temperature detection signals with the first preset temperature; and control the intensity of the AC signal transmitted to the dielectric element of each of the electrode units according to the comparison result.

13. The electric field generator according to claim 11, characterized in that, The electric field generator is also configured to: When all the temperature detection signals are less than the first preset temperature, the grounding switches and bidirectional switching switches are controlled in combination to transmit AC signals with increased or constant strength to the dielectric elements of the electrode units via the dual-purpose signal lines. When there is a temperature detection signal greater than the first preset temperature and all temperature detection signals are less than the preset temperature threshold, the grounding switch and the bidirectional switching switch are combined to make the AC signal transmitted from each dual-purpose signal line to the dielectric element of each electrode unit maintain a constant or reduced strength. When a temperature detection signal exceeds the preset temperature threshold, the grounding switch and the bidirectional switching switch are controlled in combination to stop all dual-purpose signal lines from transmitting AC signals to the dielectric elements of each electrode unit; or the dual-purpose signal line corresponding to the column group of the electrode unit where the temperature detection signal exceeds the preset temperature threshold stops transmitting AC signals and the remaining dual-purpose signal lines transmit AC signals.

14. The electric field generator according to claim 1, characterized in that, The electric field generator is also configured to: control each of the grounding switches and each of the bidirectional switching switches to stop transmitting AC signals to the dielectric elements of each of the electrode units and to stop transmitting DC signals to the temperature sensors of each of the electrode units.

15. A tumor electric field therapy system, characterized in that, It includes: An electrode sheet includes a flexible circuit board with multiple grounding lines and multiple dual-purpose signal lines therein, and multiple electrode units disposed on the flexible circuit board. Each electrode unit has a dielectric element for applying an AC signal and a temperature sensor for detecting temperature, having a grounding terminal and a signal terminal. The signal terminal of the temperature sensor of each electrode unit is short-circuited to its dielectric element. The multiple electrode units are configured in the circuit as multiple row groups and multiple column groups. The grounding terminals of the temperature sensors of each electrode unit located in the same row group are all short-circuited through the same grounding line. The grounding terminals of the temperature sensors of each electrode unit located in different row groups are respectively connected in parallel through different grounding lines. The dielectric element and the signal terminal of the temperature sensor of each electrode unit located in the same column group are all short-circuited through the same dual-purpose signal line. The dielectric element and the signal terminal of the temperature sensor of each electrode unit located in different column groups are respectively connected in parallel through different dual-purpose signal lines. as well as The electric field generator as described in any one of claims 1 to 13.

16. A method for detecting the temperature of an electrode sheet, characterized in that, The method, applied to an electric field generator as described in any one of claims 1-13 or a tumor electric field therapy system as described in claim 14, comprises: Control each of the bidirectional switching switches of the electric field generator to disconnect the AC signal applied to the dielectric element of each of the electrode units, and at the same time connect the DC signal applied to the signal terminal of the temperature sensor of each of the electrode units; Each of the grounding switches of the electric field generator is turned on individually in sequence to obtain the temperature detection signal of the temperature sensor of each of the electrode units.

17. The method according to claim 15, characterized in that, Based on the temperature detection signals of each temperature sensor of the obtained electrode sheet, at least one of the following judgments is made: (1) whether the temperature sensor of the electrode sheet is faulty or abnormal; (2) whether the electrode sheet is qualified; (3) whether the electrode sheet needs to be replaced; (4) if the electrode sheet is qualified, identify the type of the electrode sheet; (5) if the electrode sheet is qualified, determine whether the electrode unit of the electrode sheet is over-temperature.

18. A method for detecting over-temperature of an electrode sheet, characterized in that: The method, applied to an electric field generator as described in any one of claims 1-13 or a tumor electric field therapy system as described in claim 14, comprises: The combination controls each of the grounding switches and each of the bidirectional switching switches of the electric field generator, causing each of the electrode units to enter a first mode in which an AC signal is applied through its dielectric element. The combination control of each of the grounding switches and each of the bidirectional switching switches of the electric field generator enables each of the electrode units to enter a second mode that detects temperature through its temperature sensor to obtain the temperature of each of the electrode units. The temperature of each electrode unit is compared with a preset temperature threshold, and the working state of each electrode unit is determined based on the comparison result.

19. The method according to claim 17, characterized in that, The electric field generator is configured as follows: When the temperature of each electrode unit of the electrode sheet is much lower than the preset temperature threshold, the dual-purpose signal line is controlled to transmit an AC signal with an increased or unchanged voltage or current amplitude to the dielectric element of each electrode unit.

20. The method according to claim 17, characterized in that, The electric field generator is configured as follows: When there are electrode units on the electrode sheet that are below but close to the preset temperature threshold, the dual-purpose signal line is controlled to transmit an AC signal with reduced voltage or current amplitude to each electrode unit.

21. The method according to claim 17, characterized in that, The electric field generator is configured as follows: When there are electrode units on the electrode sheet with a temperature greater than the preset temperature threshold, the dual-purpose signal line is controlled to stop transmitting the AC signal to each electrode unit.

22. The method according to claim 17, characterized in that, The electric field generator is configured as follows: When there is an electrode unit on the electrode sheet with a temperature greater than the preset temperature threshold, the grounding switch and the bidirectional switching switch are controlled in combination to stop the transmission of AC signals to the electrode unit by the dual-purpose signal line, or to stop the transmission of AC signals by the dual-purpose signal line corresponding to the column group of the electrode unit whose temperature detection signal exceeds the preset temperature threshold, and to allow the remaining dual-purpose signal lines to transmit AC signals.

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