Tumor electric field therapy system, method for detecting temperatures and over-temperatures of electrode pads

Abstract

The invention provides a tumor electric field treatment system, an electrode slice temperature detection method and an electrode slice overtemperature detection method, the system comprises an electrode slice and a controller, the electrode slice comprises a flexible circuit board and a plurality of electrode units which are arranged on the flexible circuit board and are arranged on a circuit in multiple rows and multiple columns, and each electrode unit is provided with a dielectric element and a temperature sensor. The flexible circuit board is provided with a plurality of grounding wires and a plurality of dual-purpose signal wires, each grounding wire is in short circuit connection with the grounding ends of the temperature sensors in the corresponding row, and each dual-purpose signal wire is connected with the dielectric elements of the electrode units in the corresponding column and the signal ends of the temperature sensors. And the controller controls the dual-purpose signal line electrically connected with the target electrode unit to switch to access an alternating current signal or a direct current signal so as to apply the alternating current signal to the target electrode unit or collect the temperature of the target electrode unit.

Description

(19) State Intellectual Property Office (12) Invention Patent Application (10) Application Publication Number (43) Application Publication Date (21) Application Number 202511685370.8 (22) Application Date 2024.10.25 (66) Domestic Priority Data 202311809226.1 2023.12.26 CN PCT / CN2023 / 142515 2023.12.27 CN (62) Divisional Application Data 202411500665.9 2024.10.25 (71) Applicant Jiangsu Hailai Xinchuang Medical Technology Co., Ltd. Address 214100, 7th Floor, Building 7, Area A and Area B, No. 1699 Huishan Avenue, Huishan Economic Development Zone, Wuxi City, Jiangsu Province District applicant Hangzhou Hailai Xinchuang Medical Technology Co., Ltd. (72) Inventor Shen Qichao Ying Jianjun Yu Jinghui Jiajie Zhang Jun requested that the name not be disclosed Hu Tao (51) Int.Cl. A61N 1 / 36 (2006.01) A61N 1 / 04 (2006.01) G01K 13 / 00 (2021.01) G01K 13 / 20 (2021.01) G01N 25 / 00 (2006.01) G01R 31 / 00 (2006.01) H01R 13 / 70 (2006.01) (54) Invention Title: Tumor Electric Field Therapy System, Electrode Temperature Detection Method, and Electrode Overheat Detection Method (57) Abstract: This application provides a tumor electric field therapy system, an electrode temperature detection method, and an electrode overheat detection method. The system includes an electrode and a controller. The electrode includes a flexible circuit board and multiple electrode units arranged in multiple rows and columns on the flexible circuit board. Each electrode unit is equipped with a dielectric element and a temperature sensor. The flexible circuit board is equipped with multiple grounding lines and multiple dual-purpose signal lines. Each grounding line is short-circuited to the grounding terminal of each temperature sensor in the corresponding row. Each dual-purpose signal line is connected to the signal terminal of the dielectric element and the temperature sensor of each electrode unit in the corresponding column. The controller controls the dual-purpose signal lines electrically connected to the target electrode unit to switch between AC or DC signals to achieve AC signal application to the target electrode unit or to collect the temperature of the target electrode unit. Claims (3 pages), Description (43 pages), Drawings (27 pages), CN 121288195 A 2026.01.09 CN 1 21 28 81 95 A 1. A tumor electric field therapy system, characterized in that: it comprises: an electrode sheet, which includes a flexible circuit board having multiple grounding wires and multiple dual-purpose signal lines therein, and multiple electrode units disposed on the flexible circuit board, each electrode unit having a dielectric element for applying an alternating current signal and a temperature sensor for detecting temperature and having a grounding terminal and a signal terminal, wherein the signal terminal of the temperature sensor of the electrode unit is connected to...The dielectric elements are short-circuited; the multiple electrode units are configured in the circuit as multiple row groups and multiple column groups, wherein the grounding terminals of the temperature sensors of each electrode unit located in the same row group are all short-circuited through the same grounding line, and the grounding terminals of the temperature sensors of each electrode unit located in different row groups are respectively connected in parallel through different grounding lines; the dielectric elements and signal terminals of the temperature sensors of each electrode unit located in the same column group are all short-circuited through the same dual-purpose signal line, and the dielectric elements and signal terminals of the temperature sensors of each electrode unit located in different column groups are respectively connected in parallel through different grounding lines. The dual-purpose signal lines are connected in parallel; and a controller is configured to: (1) determine the area where a target electrode unit needs to be applied an AC signal or have its temperature collected; (2) control the dual-purpose signal lines electrically connected to the area to be in a first mode to transmit an AC signal to the target electrode unit; (3) control the dual-purpose signal lines electrically connected to the area to be in a second mode to transmit a DC signal to the target electrode unit to collect the temperature of the target electrode unit; wherein, in the first mode, the target electrode unit applies an AC signal through its dielectric element and in the second mode, it detects or collects its temperature through its temperature sensor. 2. The tumor electric field therapy system according to claim 1, characterized in that it is provided with a plurality of bidirectional switching switches, each of the dual-purpose signal lines is connected in series with a corresponding bidirectional switching switch, the bidirectional switching switch having an input terminal for receiving an AC signal and a collection terminal for receiving a DC signal, and the controller is configured to: control the bidirectional switching switch to conduct its input terminal in the first mode to allow the dual-purpose signal line to receive an AC signal and to conduct its collection terminal in the second mode to allow the dual-purpose signal line to receive a DC signal. 3. The tumor electric field therapy system according to claim 2, characterized in that it is provided with multiple grounding switches, each grounding wire is connected in series with a corresponding grounding switch and grounded through the corresponding grounding switch, and the controller is configured to: control all the grounding switches to be disconnected in a first mode, and sequentially turn on each grounding wire in a second mode to collect the temperature detection signals detected by each temperature sensor row by row. 4. The tumor electric field therapy system according to claim 3, characterized in that when performing temperature detection on a certain target electrode unit, the bidirectional switching switch connected to the dual-use signal line corresponding to the column group where the target electrode unit is located is individually turned on at its acquisition end to receive a DC signal, and at the same time, the grounding switch connected to the grounding wire corresponding to the row group where the target electrode unit is located is individually turned on. 5. The tumor electric field therapy system according to claim 2, characterized in that it is provided with an analog-to-digital converter, the analog-to-digital converter is provided with multiple detection channels, and the acquisition end of each bidirectional switching switch is electrically connected to a corresponding detection channel.6. The tumor electric field therapy system according to claim 2, characterized in that an AC signal line is provided, and the input terminals of each of the bidirectional switching switches are electrically connected to the AC signal line. 7. The tumor electric field therapy system according to claim 1, characterized in that the electrode unit further has a third mode, in which the electrode unit stops applying AC signals and stops detecting or acquiring temperature. 8. The tumor electric field therapy system according to claim 1, characterized in that the controller is further configured to: determine the working state of each of the electrode units according to the temperature detection signals of each of the temperature sensors. 9. The tumor electric field therapy system according to claim 8, characterized in that a preset temperature threshold is provided, and the controller is configured to: compare the temperature detection signals of each of the temperature sensors with the preset temperature threshold; determine the working mode of each of the bidirectional switching switches according to the comparison result. 10. The tumor electric field therapy system according to claim 9, wherein the controller is configured to: when all the temperature detection signals are less than the preset temperature threshold, combine and control each of the grounding switches and each of the bidirectional switching switches to allow each of the dual-purpose signal lines to continue transmitting AC signals to the dielectric elements of each of the electrode units; when one of the temperature detection signals exceeds the preset temperature threshold, combine and control each of the grounding switches and each of the bidirectional switching switches to allow each of the dual-purpose signal lines to stop transmitting AC signals to the dielectric elements of each of the electrode units; or allow the dual-purpose signal lines corresponding to the column group of the electrode unit exceeding the preset temperature threshold to stop transmitting AC signals to the dielectric elements of each of the electrode units in that column group, and allow the remaining dual-purpose signal lines to continue transmitting AC signals to the dielectric elements of the electrode units in their corresponding columns. 11. The tumor electric field therapy system according to claim 9, characterized in that the controller is configured to: when the temperature detection signal of each of the temperature sensors is much lower than the preset temperature threshold, control each of the dual-purpose signal lines to continue transmitting the AC signal to the dielectric element of each of the electrode units in a manner that increases the strength of the currently transmitted AC signal or maintains the strength of the currently transmitted AC signal unchanged; when the temperature detection signal of at least one of the temperature sensors is close to the preset temperature threshold, control each of the dual-purpose signal lines to continue transmitting the AC signal to the dielectric element of each of the electrode units in a manner that maintains the strength of the currently transmitted AC signal unchanged or decreases the strength of the currently transmitted AC signal; when the temperature detection signal of at least one of the temperature sensors exceeds the preset temperature threshold, control the dual-purpose signal lines to continue transmitting the AC signal to the dielectric element of each of the electrode units.The signal line is used to stop transmitting the AC signal to the dielectric element of each electrode unit; or the dual-purpose signal line corresponding to the electrode unit whose temperature detection signal exceeds the preset temperature threshold is controlled to stop transmitting the AC signal to the dielectric element of each electrode unit in its corresponding column group, and the remaining dual-purpose signal lines are controlled to continue transmitting the AC signal to the dielectric element of each electrode unit in its corresponding column group. 12. The tumor electric field therapy system according to claim 9, characterized in that the controller has a first preset temperature less than the preset temperature threshold, and the controller is configured to: when the temperature detection signals of each of the temperature sensors are all less than the first preset temperature, control each of the dual-purpose signal lines to increase the intensity of the currently transmitted AC signal and continue transmitting the AC signal to the dielectric element of each of the electrode units; when the temperature detection signals of each of the temperature sensors are all less than the preset temperature threshold and at least one of the temperature sensors has a temperature detection signal exceeding the first preset temperature, control each of the dual-purpose signal lines to continue transmitting the AC signal to the dielectric element of each of the electrode units in a manner that either maintains the intensity of the currently transmitted AC signal unchanged or decreases the intensity of the currently transmitted AC signal; When the temperature detection signal of at least one of the temperature sensors exceeds the preset temperature threshold, control each of the dual-purpose signal lines to stop transmitting the AC signal to the dielectric element of each of the electrode units; or control the dual-purpose signal line corresponding to the electrode unit whose temperature detection signal exceeds the preset temperature threshold to stop transmitting the AC signal to the dielectric element of each of the electrode units in its corresponding column group and control the remaining dual-purpose signal lines to continue transmitting the AC signal to the dielectric element of each of the electrode units in their corresponding column group. 13. An electrode sheet temperature detection method, characterized in that it is applied to a tumor electric field therapy system as described in any one of claims 1 to 12, the method comprising: controlling each of the dual-purpose signal lines to disconnect from the AC signal to stop applying the AC signal to the dielectric element of each of the electrode units, and simultaneously connecting a DC signal to transmit the DC signal to the signal terminal of the temperature sensor of each of the electrode units; controlling each of the grounding lines to be grounded individually in sequence to obtain the temperature detection signal of the temperature sensor of each of the electrode units. 14. The method according to claim 13, characterized in that, based on the temperature detection signals of each temperature sensor of the obtained electrode sheet, at least one of the following conditions is determined: (1) whether the temperature sensor of the electrode sheet is faulty or abnormal; (2) whether the electrode sheet is qualified; (3) whether the electrode sheet needs to be replaced; (4) in(5) If the electrode sheet is qualified, identify the type of the electrode sheet; if the electrode sheet is qualified, determine whether the electrode unit of the electrode sheet is overheated. 15. An electrode sheet overheat detection method, characterized in that: applied to the tumor electric field therapy system as described in any one of claims 1-12, the method includes: combining control of each of the grounding switches and each of the bidirectional switching switches to make each of the electrode units enter a first mode of applying an AC signal through its dielectric element; combining control of each of the grounding switches and each of the bidirectional switching switches to make each of the electrode units enter a second mode of obtaining the temperature of each of the electrode units by detecting or acquiring the temperature through its temperature sensor; comparing the temperature of each of the electrode units with a preset temperature threshold, and determining the working state of each of the electrode units based on the comparison result. 16. The method according to claim 15, characterized in that, when there are electrode units in the electrode sheet that are greater than the preset temperature threshold, the dual-purpose signal line is configured to stop transmitting the AC signal to each of the electrode units. Claims 3 / 3 Page 4 CN 121288195 A Tumor Electric Field Therapy System, Electrode Temperature Detection Method and Electrode Overheat Detection Method

[0001] This application is a divisional application of the invention patent application filed by the applicant on October 25, 2024, with application number 202411500665.9, entitled "Tumor Electric Field Therapy System and Temperature Detection Method and Signal Control Method". Technical Field

[0002] This application relates to Tumor Treating Fields (TTF) technology, and more particularly to a tumor electric field therapy system, an electrode temperature detection method and an electrode overheat detection method. Background Art

[0003] Tumor electric field therapy is a method that uses a low-intensity, medium-to-high frequency alternating electric field to prevent the formation of spindle microtubules during the mitosis of certain tumor cells, thereby inhibiting the separation of intracellular organelles during cell division and inducing apoptosis during mitosis, thus achieving the purpose of treating tumors.

[0004] Compared with traditional cancer treatment methods, TTF has an innovative mechanism of action. Some physiological characteristics of tumor cells, such as their geometry and high-frequency mitosis, make them susceptible to TTF. TTF disrupts the normal aggregation of tubulin by applying directional forces to polar particles (such as macromolecules and organelles) within the cell. These processes may lead to physical damage to the cell membrane and apoptosis. During the telophase of mitosis, the morphology of the cleavage groove leads to an uneven distribution of the electric field around it. Simultaneously, under the influence of TTF, the electric field strength at the cleavage groove is significantly enhanced, causing charged substances in the cell to move towards the cleavage groove, interfering with or even destroying the formation of cell structures, ultimately leading to cell division failure and apoptosis.

[0005] In existing tumor electric field therapy systems, an electric field generator is used to transmit an alternating current signal for tumor electric field therapy to an electrode pad, which then applies an alternating electric field to the patient's tumor site for tumor electric field therapy. When the tumor treatment electric field is applied to the patient's body, heat accumulates at the electrode pad application site, and the temperature of the electrode pad application site also rises accordingly. Therefore, it is necessary to monitor the temperature of the electrode pad application site in real time. When the monitored temperature rises to a certain preset value, the electric field strength applied to the patient's tumor site needs to be adjusted in time to avoid the temperature of the electrode pad application site being too high and causing burns to the patient's skin.

[0006] The tumor electric field therapy system includes at least one pair of electrode pads, and each electrode pad contains multiple electrode units. Even if the same alternating current signal is applied to each electrode unit, the heat generated on each electrode unit will vary depending on its location. That is, the temperature of each electrode unit on the entire electrode pad will not be completely uniform. This may result in the temperature of some electrode units on the entire electrode pad exceeding the preset temperature, while the temperature of other electrode units remains normal. To avoid excessively high body surface temperature during prolonged tumor electric field therapy, and to ensure that an alternating electric field can be applied to the tumor site for an extended period, it is necessary to individually control the overheating electrode units. However, for existing electrode sheets, individual control of electrode units requires setting a conductive trace for each electrode unit in the electrode sheet substrate. This increases the number of conductive traces in the electrode sheet substrate, making the electrode sheet difficult to bend, and also thickens the cables electrically connected to the electrode sheet, increasing the overall weight of the electrode sheet and hindering its application.

[0007] Therefore, it is necessary to provide a tumor electric field therapy system, an electrode sheet temperature detection method, and an electrode sheet overheat detection method that use fewer conductive traces to control multiple electrode units in a zoned manner. Specification 1 / 43 pages 5 CN 121288195 A Summary of the Invention

[0008] The first objective of this application is to provide a tumor electric field therapy system to solve or eliminate the problems in the related art.

[0009] The second objective of this application is to provide an electrode sheet temperature detection method.

[0010] A third objective of this application is to provide a method for detecting overheating of an electrode sheet.

[0011] To achieve the above objective, a first aspect of this application provides a tumor electric field therapy system, comprising: an electrode sheet, which includes a flexible circuit board having multiple grounding wires and multiple dual-purpose signal lines therein, and multiple electrode units disposed on the flexible circuit board. Each electrode unit has a dielectric element for applying an alternating current signal and a temperature sensor for detecting temperature, having a grounding terminal and a signal terminal. The signal terminal of the temperature sensor of the electrode unit is short-circuited to its dielectric element. The multiple electrode units are configured in the circuit as multiple row groups and multiple column groups, wherein the electrode units located in the same row group are...The grounding terminals of the temperature sensors of each of the electrode units are all shorted through the same grounding line, and the grounding terminals of the temperature sensors of each of the electrode units located in different rows are connected in parallel through different grounding lines; the signal terminals of the dielectric elements and temperature sensors of each of the electrode units located in the same column are all shorted through the same dual-purpose signal line, and the signal terminals of the dielectric elements and temperature sensors of each of the electrode units located in different columns are connected in parallel through different dual-purpose signal lines; and a controller configured to: (1) determine the area where a target electrode unit needs to be applied an AC signal or have its temperature collected; (2) control the dual-purpose signal line electrically connected to the area to be in a first mode to transmit an AC signal to the target electrode unit; (3) control the dual-purpose signal line electrically connected to the area to be in a second mode to transmit a DC signal to the target electrode unit to collect the temperature of the target electrode unit; wherein, in the first mode, the electrode unit applies an AC signal through its dielectric element and in the second mode, it detects or collects the temperature through its temperature sensor.

[0012] The controller of the tumor electric field therapy system according to the first aspect of this application is configured to connect a dual-purpose signal line electrically connected to the target electrode unit to an AC signal in a first mode and a DC signal in a second mode, so that AC signals can be applied to the target electrode unit or the temperature of the target electrode unit can be collected using fewer conductive traces.

[0013] To achieve the above objective, the second aspect of this application provides an electrode temperature detection method applied to the aforementioned tumor electric field therapy system. The method includes: controlling each of the dual-purpose signal lines to disconnect from the AC signal to stop applying AC signals to the dielectric element of each of the electrode units, while simultaneously connecting a DC signal to transmit DC signals to the signal terminal of the temperature sensor of each of the electrode units; controlling each of the grounding lines to be grounded individually in sequence to obtain the temperature detection signal of the temperature sensor of each of the electrode units.

[0014] To achieve the above objectives, a third aspect of this application provides an electrode overheat detection method, applied to the aforementioned tumor electric field therapy system. The method includes: combining and controlling each of the grounding switches and each of the bidirectional switching switches to enable each of the electrode units to enter a first mode in which an AC signal is applied through its dielectric element; combining and controlling each of the grounding switches and each of the bidirectional switching switches to enable each of the electrode units to enter a second mode in which the temperature is detected or acquired by its temperature sensor to obtain the temperature of each of the electrode units; comparing the temperature of each of the electrode units with a preset temperature threshold, and determining the working state of each of the electrode units based on the comparison result.

[0015] The above description is only an overview of the technical solution of this application. In order to better understand the technical means of this application,The invention can be implemented in accordance with the contents of the specification, and in order to make the above and other objects, features and advantages of this application more apparent and understandable, specific embodiments of this application are described below. Specification 2 / 43 pages 6 CN 121288195 A Description of Drawings

[0016] Figure 1 is a schematic diagram of a frame of a tumor electric field therapy system according to a first embodiment of the present application, showing a schematic diagram of the structure of the electrode sheet of the first embodiment;

[0017] Figure 2 is a schematic diagram of a modified embodiment of the electrode sheet of the tumor electric field therapy system shown in Figure 1 of the present application;

[0018] Figure 3 is a schematic diagram of the circuit connection of the tumor electric field system shown in Figure 1 of the present application, showing a schematic diagram of the circuit connection between the electrode sheet of the first embodiment shown in Figure 1 or the electrode sheet of the modified embodiment shown in Figure 2 and the adapter shown in the first embodiment shown in Figure 1;

[0019] Figure 4 is a schematic block diagram of the internal structure of the adapter shown in Figure 3 of the present application;

[0020] Figure 5 is a schematic block diagram of the internal structure of the electric field generator of the tumor electric field therapy system shown in Figure 1 of the present application;

[0021] Figure 6 is similar to Figure 3, and is a schematic diagram of the circuit connection of a tumor electric field therapy system according to a second embodiment of the present application, showing a schematic diagram of the circuit connection between the electrode sheet of the second embodiment of the tumor electric field therapy system and the adapter shown in Figure 3.

[0022] Figure 7, similar to Figure 3, is a circuit connection diagram of the tumor electric field therapy system according to the third embodiment of this application, showing the circuit connection diagram between the electrode sheet of the third embodiment of the tumor electric field therapy system and the adapter of the second embodiment;

[0023] Figure 8, similar to Figure 3, is a circuit connection diagram of the tumor electric field therapy system according to the fourth embodiment of this application, showing the circuit connection diagram between the electrode sheet of the fourth embodiment of the tumor electric field therapy system and the adapter of the second embodiment;

[0024] Figure 9 is a schematic block diagram of the internal structure of the adapter of the second embodiment of the tumor electric field therapy system shown in Figures 7 and 8;

[0025] Figure 10, similar to Figure 1, is a framework diagram of the tumor electric field therapy system according to the fifth embodiment of this application, showing the structural diagram of the electrode sheet of the fifth embodiment;

[0026] Figure 11(A) is a structural diagram of a modified embodiment of the electrode sheet of the fifth embodiment of the tumor electric field therapy system shown in Figure 10;

[0027] Figure 11(B) is similar to Figure 11(A), and is a schematic diagram of another modified embodiment of the electrode sheet of the fifth embodiment of the tumor electric field therapy system of this application shown in Figure 10;

[0028] Figure 12 is similar to Figure 3, and is a schematic diagram of a circuit connection of the tumor electric field therapy system shown in Figure 10, which shows the electrode sheet of the fifth embodiment shown in Figure 10 or the electrode sheet of the modified embodiment shown in Figures 11(A) and 11(B) and the third embodiment.Schematic diagram of circuit connection of the adapter in the embodiment;

[0029] FIG13 is similar to FIG12, and is a schematic diagram of circuit connection of the tumor electric field therapy system of the sixth embodiment of the present application, which shows another schematic diagram of circuit connection between the electrode plate of the sixth embodiment of the tumor electric field therapy system of the present application and the adapter of the third embodiment;

[0030] FIG14 is a schematic block diagram of the internal structure of the adapter of the third embodiment of the tumor electric field therapy system of the present application shown in FIG12 and FIG13;

[0031] FIG15 is similar to FIG12, and is a schematic diagram of circuit connection of the tumor electric field therapy system of the seventh embodiment of the present application, which shows another schematic diagram of circuit connection between the electrode plate of the seventh embodiment of the tumor electric field therapy system of the present application and the adapter of the fourth embodiment; Specification 3 / 43 pages 7 CN 121288195 A

[0032] FIG16 is similar to FIG15, and is a schematic diagram of circuit connection of the tumor electric field therapy system of the eighth embodiment of the present application, which shows another schematic diagram of circuit connection between the electrode plate of the eighth embodiment of the tumor electric field therapy system of the present application and the adapter of the fourth embodiment;

[0033] Figure 17 is a schematic block diagram of the internal structure of the adapter for the fourth embodiment of the tumor electric field therapy system of this application shown in Figures 15 and 16;

[0034] Figure 18 is similar to Figure 1, and is a schematic diagram of the framework of the tumor electric field therapy system of the ninth embodiment of this application, showing a schematic diagram of the structure of the electrode sheet of the ninth embodiment;

[0035] Figure 19 is a schematic diagram of the circuit connection of the tumor electric field therapy system shown in Figure 18, showing a schematic diagram of the circuit connection between the electrode sheet of the ninth embodiment shown in Figure 18 and the adapter of the fifth embodiment;

[0036] Figure 20 is a schematic block diagram of the internal structure of the adapter for the fifth embodiment of the tumor electric field therapy system of this application shown in Figure 19;

[0037] Figure 21 is similar to Figure 19, and is a schematic diagram of the circuit connection of the tumor electric field therapy system of the tenth embodiment of this application, showing a schematic diagram of the circuit connection between the electrode sheet of the tenth embodiment of the tumor electric field therapy system of this application and the adapter of the sixth embodiment;

[0038] Figure 22 is a schematic block diagram of the internal structure of the adapter for the sixth embodiment of the tumor electric field therapy system of this application shown in Figure 21;

[0039] Figure 23 is a flowchart illustrating a temperature detection method for a tumor electric field therapy system according to an embodiment of this application;

[0040] Figure 24 is a flowchart illustrating a control method for applying an alternating current signal for tumor electric field therapy according to an embodiment of this application;

[0041] Figure 25 is a flowchart illustrating a signal control method for tumor electric field therapy according to an embodiment of this application;

[0042] Figure 26 is a flowchart illustrating an electrode temperature detection method according to another embodiment of this application;

[0043] Figure 27 is a flowchart illustrating a control method for applying an alternating current signal for tumor electric field therapy according to another embodiment of this application;

[0044] Figure 28 is a flowchart illustrating an AC signal application method based on a temperature detection signal according to an embodiment of this application;

[0045] Figure 29 is a flowchart illustrating an AC signal application method based on a temperature detection signal according to another embodiment of this application.

[0046] Explanation of reference numerals:

[0047] Tumor electric field therapy system 100, 100D, 100G; Electrode sheets 10, 10', 10A, 10B, 10C, 10D, 10D', 10D'', 10E, 10F, 10G, 10H, 10J; Flexible circuit boards 11, 11A, 11B, 11C, 11D, 11E, 11F, 11G, 11H, 11J; Connecting parts 111, 111'; Wiring parts 112, 112'; Bridging parts 113, 113'; Electrode unit 12; First cable 13, 13', 13D, 13D' 13D, Temperature sensor 14, Grounding terminal 14-1, Signal terminal 14-2, Dielectric element 15, Diode 16, Grounding wire 18, First grounding wire 18-1, Second grounding wire 18-2, Third grounding wire 18-3, Fourth grounding wire 18-4, Fifth grounding wire 18-5, Dual-purpose signal line 19, First dual-purpose signal line 19-1, Second dual-purpose signal line 19-2, Third dual-purpose signal line 19-3, Fourth dual-purpose signal line 19-4, Fifth dual-purpose signal line 19-5, Sixth dual-purpose signal line 19-6, Adapter 20, 20A, 20B, 20C, 20D, 20E, Second cable 21, First controller 22, Analog-to-digital converter 23 24. Voltage divider resistor; 25. Grounding switch; 25-1 first grounding switch; 25-2 second grounding switch; 25-3 third grounding switch; 25-4 fourth grounding switch; 25-5 fifth grounding switch; 26. Bidirectional changeover switch; 26-1 first bidirectional changeover switch; 26-2 second bidirectional changeover switch; 26-3 third bidirectional changeover switch; 26-4 fourth bidirectional changeover switch; 26-5 fifth bidirectional changeover switch; 27. First communication unit; 28. AC signal line; 29. ​​First power module; 30. Electric field generator; 31. Second power module; 32. Second controller; 33. Second communication unit; 34. AC signal generator; AC signal switch instruction manual 4 / 43 Page 8 CN 121288195 A 35, First AC signal switch 35-1, Second AC signal switch 35-2, Third AC signal switch 35-3, Fourth AC signal switch 35-4, AC signal wiring 36, First AC signal wiring 36-1, Second AC signal wiring 36-2, Third AC signal wiring 36-3, Fourth AC signal wiring 36-4, First connectors 40, 40A, 40B, 40C, 40D, 40E, First plugs 41, 41', 41D, 41D', 41D", First socket 42, Second connector 50, Second plug 51, Second socket 52. Detailed implementation

[0048] The embodiments of the technical solutions of this application will be described in detail below with reference to the accompanying drawings. The following embodiments are only used to illustrate the technical solutions of this application more clearly, and are therefore only examples and cannot be used to limit the scope of protection of this application.

[0049] FIG1 is a schematic diagram of a tumor electric field therapy system 100 according to an embodiment of this application. As shown in FIG1, the tumor electric field therapy system 100 includes: at least one pair of electrode plates 10, an adapter 20 electrically connected to the electrode plates 10, and an electric field generator 30 electrically connected to the adapter 20. The electric field generator 30 generates an alternating current signal for tumor treatment and applies the alternating current signal to the electrode plates 10 through the adapter 20 to generate an alternating current signal on the paired electrode plates 10. The adapter 20 is electrically connected between the electrode plates 10 and the electric field generator 30 for transmitting the alternating current signal generated by the electric field generator 30 to the electrode plates 10. In other words, the electric field generator 30 can generate an alternating current signal, which is transmitted to each electrode 10 through the adapter 20, so that a therapeutic electric field for treating tumors is generated between the same pair of electrode 10.

[0050] As shown in FIG1, in this embodiment, there are 4 electrode 10s. From the spatial structural arrangement, each electrode 10 includes multiple electrode units 12 arranged in both axially symmetrical and centrally symmetrical positions and in the same number, several connecting parts 111 located between two adjacent electrode units 12, a bridging part 113 erected between two adjacent connecting parts 111, a wiring part 112 connected to the bridging part 113, and a first cable 13 connected to the wiring part 112. The bridging part 113 and the wiring part 112 are arranged perpendicularly to each other, forming a "T" shape. The bridging part 113 is erected between two adjacent connecting parts 111. Each electrode unit 12 of the electrode 10 is electrically connected to the adapter 20 through the first cable 13.

[0051] Each electrode unit 12 has a temperature sensor 14 and a dielectric element 15. The temperature sensor 14 is used to detect the temperature of the part of the electrode unit 12 that is applied to the patient's body surface. It can be a thermistor element or a temperature sensor other than a thermistor, and can be set at any position on the electrode unit 12. The dielectric element 15 is used to apply an alternating current signal to the tumor site of the patient. The dielectric element 15 can be a dielectric ceramic sheet or a polymer dielectric layer made of polymer material. In this embodiment, each dielectric element 15 has a through hole (not labeled) in the middle for accommodating a corresponding temperature sensor 14. Each electrode unit 12 may also include a diode 16 connected in series with the temperature sensor 14 to prevent reverse current flow and prevent detection signals from other electrode units 12 from affecting the temperature sensor 14. The ground terminal 14-1 of the temperature sensor 14 is connected in series with the anode of the diode 16 and grounded through the cathode of the diode 16.

[0052] In the first mode, electrode unit 12 applies an alternating current signal through dielectric element 15; in the second mode, it detects or acquires the temperature of the patient's body surface to which the corresponding electrode unit 12 is applied through temperature sensor 14; in the third mode, it stops applying the alternating current signal and stops temperature detection and acquisition. The first, second, and third modes do not overlap in time periods. That is, the time period during which the dielectric element 15 of electrode unit 12 applies the alternating current signal is staggered and does not overlap with the time period during which the temperature sensor 14 detects the temperature. Electrode unit 12 can cycle between applying an alternating current signal through its dielectric element 15 and detecting the temperature through its temperature sensor 14, i.e., electrode unit 12 can cycle between the first and second modes. Electrode unit 12 can also cycle between the first, second, and third modes, i.e., electrode unit 12 cycles between applying an alternating current signal through dielectric element 15, acquiring or detecting the temperature through temperature sensor 14, stopping the application of alternating current, and acquiring the temperature.

[0053] Each electrode sheet 10 includes an electrode array (unlabeled) consisting of 20 electrode units 12. The electrode array (unlabeled) also has a flexible circuit board 11 including a connecting part 111, a wiring part 112, and a bridging part 113. The 20 electrode units 12 are distributed in a spaced manner in an electrode array (unlabeled) arranged in four rows and six columns. Specifically, the first and last rows each have four electrode units 12, and the middle two rows each have six electrode units 12. The four electrode units 12 in the first row are located in the second to fifth columns, the six electrode units 12 in each of the middle two rows are located in the first to sixth columns, and the four electrode units 12 in the last row are also located in the second to fifth columns.

[0054] The connecting portion 111 is located only between two adjacent electrode units 12 arranged in the column direction in each of the third and fourth columns, and between two adjacent electrode units 12 arranged in the row direction in each row, except for the two electrode units 12 located in the third and fourth columns in each row. That is, the two adjacent electrode units 12 located in the third and fourth columns are only connected by the connecting portion 111 in the column direction, and are disconnected and not connected by the connecting portion 111 in the row direction; the electrode units 12 located in each of the first, second, fifth, and sixth columns are only connected by the connecting portion 111 arranged in the horizontal direction and the electrode unit 12 adjacent to it in the row direction, and are disconnected in the column direction and between the electrode units 12 adjacent to it. In other words, the two adjacent electrode units 12 located in the column direction in each of the first, second, fifth, and sixth columns are disconnected.

[0055] The electrode unit 12 located in the third column and the connecting portion 111 arranged in the vertical direction between the electrode units 12 in that column.The electrode unit 12 located in the fourth column and the connecting portion 111 located between the electrode units 12 in that column and also arranged longitudinally constitute the main trunk 114 of the electrode array (unlabeled). The connecting portions 111 located on opposite sides of the electrode units 12 in the third and fourth columns and connected to the electrode units 12 in the third and fourth columns respectively by the connecting portions 111 arranged laterally, and the electrode units 12 connected to the connecting portions 111 arranged laterally, constitute the branches 115 of the electrode array (unlabeled). That is, in this embodiment, the electrode array (unlabeled) includes two main trunks 114 and a number of branches 115 that extend laterally from the two main trunks 114 respectively. Each branch 115 has a free end away from the main trunk 114, and the free ends of adjacent branches 115 are disconnected. The position and distance between adjacent branches 115 can be freely adjusted according to the actual usage scenario. Specifically, one main branch 114 is composed of each electrode unit 12 located in the third column and a connecting portion 111 arranged longitudinally between adjacent electrode units 12 in that column. The other main branch 114 is composed of each electrode unit 12 located in the fourth column and a connecting portion 111 arranged longitudinally between adjacent electrode units 12 in that column. The remaining electrode units 12 connected to the main branches 114 via transversely arranged connecting portions 111 are all branches 115.

[0056] Specifically, the branches 115 are: a connecting portion 111 extending laterally to the left from the electrode unit 12 in the first row of the third column and located in the first row, and an electrode unit 12 connected to the connecting portion 111 and located in the second column of the first row; two connecting portions 111 extending laterally to the left from the electrode unit 12 in the second row of the third column and located in the second row, and two electrode units 12 located in the first column and second column of the second row; two connecting portions 111 extending laterally to the left from the electrode unit 12 in the third row and located in the third row, and two electrode units 12 located in the first column and second column of the third row; a connecting portion 111 extending laterally to the left from the electrode unit 12 in the fourth row and located in the fourth row, and two electrode units 12 located in the first column and second column of the third row; Electrode unit 12 in the second column of the fourth row; a connecting portion 111 extending laterally to the right from the electrode unit 12 in the first row of the fourth row and located in the first row, and an electrode unit 12 located in the fifth column of the first row; two connecting portions 111 extending laterally to the right from the electrode unit 12 in the second row of the fourth row and located in the second row, and two electrode units 12 located in the fifth and sixth columns of the second row; two connecting portions 111 extending laterally to the right from the electrode unit 12 in the third row of the fourth row and located in the third row, and two electrode units 12 located in the fifth and sixth columns of the third row; a connecting portion 111 extending laterally to the right from the electrode unit 12 in the fourth row and located in the fourth row, and an electrode unit 12 located in the fifth column of the fourth row.

[0057] The electrode array (unnumbered) is divided into a symmetrical left portion comprising three columns on the left and a right portion comprising three columns on the right (see page 6 / 43, CN 121288195 A). The left and right portions are connected only by a bridging portion 113. The left portion consists of a main stem 114 located in the third column and several branches 115 extending laterally to the left from the main stem 114. The right portion consists of a main stem 114 located in the fourth column and several branches 115 extending laterally to the right from the main stem 115. The two main stems 114 are connected by a bridging portion 113 between them. Specifically, the two main stems 114 are electrically connected by a bridging portion 113 between the connecting portions 111 of the electrode units 12 in the second row of the third column and the connecting portions 111 of the electrode units 12 in the second row of the fourth column and the connecting portions 111 of the electrode units 12 in the third row of the fourth column. The connecting portion 111 connecting the electrode unit 12 in the second row of the third column to the electrode unit 12 in the third row of the third column, the connecting portion 111 connecting the electrode unit 12 in the second row of the fourth column to the electrode unit 12 in the third row of the fourth column, and the bridging portion 113 are generally arranged in an "H" shape. In other embodiments, the bridging portion 113 may also be erected between an electrode unit 12 located in the third column and an electrode unit 12 located in the fourth column. Optionally, the bridging portion 113 is erected between two electrode units 12 located in the third column and the fourth column and adjacent in the row direction.

[0058] Each electrode unit 12 can be divided into peripheral electrode units 12 and central electrode units 12 according to its position in the electrode array (unlabeled). The peripheral electrode units 12 include four electrode units 12 located in the first row, two electrode units 12 located at opposite ends of the second row, two electrode units 12 located at opposite ends of the third row, and four electrode units 12 located in the fourth row. The central electrode unit 12 includes four electrode units 12 located in the middle of the second row and four electrode units 12 located in the middle of the third row. Among the peripheral electrode units 12, some adjacent electrode units 12 are connected by a laterally arranged connecting portion 111, while some adjacent electrode units 12 are disconnected. Among the peripheral electrode units 12, the adjacent electrode units 12 connected by the connecting portion 111 are partially row-adjacent electrode units 12. Specifically, among the peripheral electrode units 12, electrode units 12 that are column-adjacent or diagonally adjacent are disconnected; some row-adjacent electrode units 12 are also disconnected; only some row-adjacent electrode units 12 are connected by a laterally extending connecting portion 111. Among the central electrode units 12, only column-adjacent electrode units 12 on the main branch 114 are connected by a longitudinally arranged connecting portion 111, and only row-adjacent electrode units 12 on the branch 115 are connected by a laterally arranged connecting portion 111.

[0059] The electrode array (unlabeled) also has gaps (unlabeled) formed between a plurality of spaced electrode units 12, which allow moisture from the patient's skin to escape, heat exchange between the patient's skin and the outside world, or free breathing of the patient's skin. It also allows for free adjustment of the position and spacing between the branches 115, and avoids wrinkling when the electrode pads 10 are applied. The gaps (unlabeled) include a first gap D1 located between the two main branches 114 and a second gap D2 located between the branches 115. The first gap D1 is located between the third and fourth columns of electrode units 12, while the second gap D2 is located between adjacent rows of electrode units 12. That is, along the row upwards, the electrode unit 12 located in the third column is disconnected from the adjacent electrode unit 12 located in the fourth column, and no connecting part 111 is provided, but instead forms the aforementioned first interval D1; and along the column upwards, only the two adjacent electrode units 12 in the third and fourth columns are connected by the connecting part 111, while the two adjacent electrode units 12 in each of the other four columns are not connected by the connecting part 111, but instead form the aforementioned second interval D2. The setting of the first and second intervals D1 and D2 can also increase the degree of freedom of some electrode units 12, and can also avoid wrinkles when attaching the electrode sheet 10.

[0060] In some other embodiments, the tumor electric field therapy system 100 may have more or fewer electrode sheets 10. In some other embodiments, each pair of electrode sheets 10 has the same number of electrode units 12, and different pairs of electrode sheets 10 may also have different numbers of electrode units 12. In some other embodiments, 20 electrode units 12 may also be arranged in other ways. Of course, in some other embodiments, the electrode sheet 10 may also have other numbers of electrode units 12. In summary, the implementation of this application is not limited by the number and arrangement of the electrode units 12 of the electrode sheet 10.

[0061] The electrode sheet 10' shown in FIG2 is a variation of the electrode sheet 10 shown in FIG1. ​​The spatial structure of the electrode sheet 10' is the same as that of the electrode sheet 10, and it also includes a plurality of electrode units 12' arranged at intervals, a plurality of connecting portions 111' located between two adjacent electrode units 12', a wiring portion 112' connected to the bridging portion 113', a first cable 13' connected to the wiring portion 112', a first interval D1 formed between the third column electrode units 12' and the fourth column electrode units 12', and a second interval D2' formed between the electrode units 12' in adjacent rows. The only difference is that: the two adjacent electrode units 12' in the fourth column are arranged in a disconnected manner and are not connected by the vertically arranged connecting portions 111', but the two adjacent electrode units 12' in the fifth column are connected by the vertically arranged connecting portions 111'.The electrode unit 12' located in the fifth column and adjacent in the row direction is connected to the horizontally arranged connecting part 111' respectively; and the bridging part 113' connects the two electrode units 12' located in the third row and third column and the two electrode units 12' located in the third row and fourth column respectively.

[0062] FIG3 is a schematic diagram of a circuit connection between the electrode sheet 10' of the first embodiment or a variation thereof for the tumor electric field therapy system 100 of the present application shown in FIG1 and the adapter 20 of the first embodiment. It is worth noting that: the arrangement of the electrode units 12 shown in FIG3 is to more clearly show the electrical connection between an electrode sheet 10 and the adapter 20. The arrangement of the electrode units 12 shown in FIG3 does not represent the spatial arrangement of the electrode units 12. The circuit connection is described below using the electrode sheet 10 in the first embodiment as an example. Referring to FIG1 and FIG3, the flexible circuit board 11 is embedded with multiple conductive traces 18, 19, which include multiple ground lines 18 and multiple dual-purpose signal lines 19. The first cable 13 has multi-core conductors (not shown) that are electrically connected one-to-one with the multiple grounding wires 18 and multiple dual-purpose signal lines 19 of the flexible circuit board 11. The total number of grounding wires 18 and dual-purpose signal lines 19 embedded in the flexible circuit board 11 does not exceed 10. Therefore, the number of conductors in the first cable 13 does not exceed 10.

[0063] In this embodiment, each electrode sheet 10 is provided with 20 electrode units 12. The 20 electrode units 12 are arranged in the order of 1 to 20 in the circuit connection and are divided into five row groups and four column groups, that is, the 20 electrode units 12 are arranged in five rows and four columns in the circuit connection. The temperature sensor 14 of each electrode unit 12 includes a ground terminal 14-1 and a signal terminal 14-2. The dielectric element 15 and the temperature sensor 14 of each electrode unit 12 are soldered to the flexible circuit board 11, and each dielectric element 15 is short-circuited to the signal terminal 14-2 of the corresponding temperature sensor 14. Since the electrode units 12 are arranged in a five-row, four-column configuration in the circuit connection, and each electrode unit includes a corresponding dielectric element 15 and a corresponding temperature sensor 14, the multiple temperature sensors 14 are also arranged in a five-row, four-column configuration in the circuit connection, and the multiple dielectric elements 15 are also arranged in a five-row, four-column configuration in the circuit connection. It should be noted that this arrangement is for clearer illustration of the electrical connection between the electrode pad 10 and the adapter 20, and does not represent the spatial arrangement of the electrode units 12. The spatial structure may be a roughly array-like structure as shown in Figure 1, or other structures, such as petal-shaped or scattering structures, and can be regular or irregular. The dielectric element 15 is configured to apply an alternating electric field to the patient's tumor site. The temperature sensor 14 is configured to detect the temperature of the patient's body surface in contact with the electrode pad 10 and output a temperature detection signal to the adapter 20.In this embodiment, the multi-purpose signal lines 19 of the flexible circuit board 11 are respectively arranged in a one-to-one correspondence with multiple columns of the electrode units 12, and are configured to transmit the AC signal generated by the electric field generator 30 to the dielectric element 15 in each electrode unit 12 in the corresponding column. That is, the dielectric elements 15 located in the same column are all short-circuited through the same multi-purpose signal line 19 of the flexible circuit board 11, and the dielectric elements 15 located in different columns are respectively connected in parallel through different multi-purpose signal lines 19 of the flexible circuit board 11. The multi-purpose signal lines 19 of the flexible circuit board 11 are electrically connected to the corresponding wires in the first cable 13, and then electrically connected to the electric field generator 30 through the adapter 20. In other words, the multi-purpose signal lines 19 of the flexible circuit board 11 receive the AC signal generated by the electric field generator 30 through the first cable 13 and the adapter 20.

[0064] The multiple grounding lines 18 are respectively configured to correspond one-to-one with the multiple rows of the electrode unit 12. The multiple grounding lines 18 are used to short-circuit and ground the temperature sensor 14 of each electrode unit 12 in each row group in sequence. That is, the grounding terminals 14-1 of the multiple temperature sensors 14 located in the same row group are all short-circuited through the same grounding line 18 of the flexible circuit board 11, and the grounding terminals 14-1 of the temperature sensors 14 located in different row groups are respectively connected and grounded in parallel through different grounding lines 18 of the flexible circuit board 11. During the time period of temperature detection or in the second mode, only one of the multiple grounding lines 18 is conducting at any given time, and the rest are disconnected.

[0065] Each of the multiple dual-purpose signal lines 19 is also configured to transmit DC signals to the temperature sensor 14 in each electrode unit 12 in the corresponding column group to collect and transmit the detected temperature signal. Multiple temperature sensors 14 located in different rows have their respective signal terminals 14-2 connected in parallel via different dual-purpose signal lines 19 on the flexible circuit board 11. Multiple temperature sensors 14 located in the same row have their respective signal terminals 14-2 shorted to the same dual-purpose signal line 19 on the flexible circuit board 11. Specifically, each dual-purpose signal line 19 is configured to short-circuit the signal terminal 14-2 of at most one electrode unit 12 of the temperature sensor 14 in each row to an external device for receiving detection signals. The signal terminals 14-2 of each temperature sensor 14 connected to each of the multiple dual-purpose signal lines 19 are different to avoid duplicate signals output by the dual-purpose signal line 19. That is, when the number of electrode units 12 in a row group is the same as the number of dual-purpose signal lines 19, each dual-purpose signal line 19 is electrically connected to the signal terminal 14-2 of the temperature sensor 14 of a different electrode unit 12 in that row group; when the number of electrode units 12 in a row group is less than the number of dual-purpose signal lines 19, there is at least one...The dual-purpose signal line 19 is not electrically connected to the signal terminal 14-2 of the temperature sensor 14 of the electrode unit 12. The remaining dual-purpose signal lines 19 are electrically connected to the signal terminal 14-2 of the temperature sensor 14 of a different electrode unit 12 in the row group. In this embodiment, the external device for receiving the detection signal is the adapter 20. The dual-purpose signal line 19 of the flexible circuit board 11 receives the DC signal from the adapter 20 or the electric field generator 30 through the first cable 13, and transmits the collected or detected temperature signal to the adapter 20, and then to the electric field generator 30 through the adapter 20.

[0066] In this embodiment, when each electrode unit 12 is equipped with a temperature sensor 14 for temperature detection, the above-mentioned circuit design reduces the number of wires in the first cable 13, avoiding the cable from becoming thicker and harder, which would increase the difficulty of cable fixation; at the same time, it avoids the increased number of wires in the first cable 13 affecting the adhesion effect between the electrode sheet 10 and the corresponding body surface of the patient's tumor site. The flexible circuit board 11 has a total of 9 embedded grounding wires 18 and dual-purpose signal lines 19. Specifically, in this embodiment, the flexible circuit board 11 has 5 embedded grounding wires 18 and 4 embedded dual-purpose signal lines 19. In other embodiments, the number of embedded grounding wires 18 and dual-purpose signal lines 19 may vary depending on the circuit arrangement and number of electrode units 12 in different electrode sheets, which will be specifically described in subsequent embodiments.

[0067] In the tumor electric field therapy system 100, the number of conductive lines electrically connected to the grounding wires 18 is related to the number of rows M of the electrode units 12, which can be greater than or equal to the number of rows M of the electrode units 12, where M is a positive integer. In the tumor electric field therapy system 100, the number of conductive lines electrically connected to the dual-purpose signal lines 19 is related to the number of columns N of the electrode units 12, which can be greater than or equal to the number of columns N of the electrode units 12, where N is a positive integer. The number of lines L embedded in the flexible circuit board 11 of the electrode sheet 10 is equal to the sum of the number of grounding lines 18 and the number of dual-purpose signal lines 19. In this embodiment, the number of grounding lines 18 is equal to the number of rows M of the electrode unit 12; the number of dual-purpose signal lines 19 is equal to the number of columns N of the electrode unit 12.

[0068] In the embodiment shown in FIG3, specifically, the electrode sheet 10 of this embodiment includes 5 grounding lines 18, each grounding line 18 being used to ground the grounding terminal 14-1 of the temperature sensor 14 in the same row group. The 5 grounding lines 18 of the electrode sheet 10 are the first grounding line 18-1, the second grounding line 18-2, the third grounding line 18-3, the fourth grounding line 18-4, and the fifth grounding line 18-5. In the five rows of electrode sheet 10, the first row includes electrode units 12-1 to 12-4, the second row includes electrode units 12-5 to 12-8, the third row includes electrode units 12-9 to 12-12, and the fourth row...The first row includes electrode units 12-13 to 12-16, and the fifth row includes electrode units 12-17 to 12-20. Specifically, the first grounding wire 18-1 is used to ground electrode units 12-1 to 12-4 in the first row; the second grounding wire 18-2 is used to ground electrode units 12-5 to 12-8 in the second row; the third grounding wire 18-3 is used to ground electrode units 12-9 to 12-12 in the third row; the fourth grounding wire 18-4 is used to ground electrode units 12-13 to 12-16 in the fourth row; and the fifth grounding wire 18-5 is used to ground electrode units 12-17 to 12-20 in the fourth row. It should be noted that these grounding wires 18 can be selectively closed or opened, which can be achieved by connecting each grounding wire 18 in series with a grounding switch, which will be described in detail below. The above-mentioned "grounding the electrode unit 12" can refer to grounding the grounding terminal 14-1 of the temperature sensor 14 in the electrode unit 12, or it can refer to the diode 16 being connected in series with the temperature sensor 14 of the same electrode unit 12 and grounded together. In short, each grounding wire 18 short-circuits and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in each row group.

[0069] Continuing to refer to FIG3, the electrode sheet 10 of this embodiment also includes four dual-purpose signal lines 19, one end of each dual-purpose signal line 19 is connected to all electrode units 12 in each column group, and the other end is connected to an adapter 20 for receiving temperature detection signals and transmitting AC signals. In other words, for each row group, each dual-purpose signal line 19 can be selectively connected to one of the electrode units 12 or not connected to any of the electrode units 12 in that row group, in order to avoid the dual-purpose signal line 19 outputting repetitive signals in the future. Specifically, the four dual-purpose signal lines 19 of the electrode sheet 10 include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, and a fourth dual-purpose signal line 19-4. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 and the signal terminal 14-2 of the respective temperature sensor 14 of five electrode units 12: electrode unit 12-1, electrode unit 12-5, electrode unit 12-9, electrode unit 12-13, and electrode unit 12-17. One end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 and the signal terminal 14-2 of the respective temperature sensor 14 of five electrode units 12: electrode unit 12-2, electrode unit 12-6, electrode unit 12-10, electrode unit 12-14, and electrode unit 12-18. One end of the third dual-purpose signal line 19-3 is simultaneously connected to electrode units 12-3, 12-7, and electrode unit 12-8.Each of the five electrode units 12 (units 12-11, 12-15, and 12-19) has its respective dielectric element 15 and signal terminal 14-2 of its respective temperature sensor 14 connected to the dielectric element 15 and signal terminal 14-2 of the respective temperature sensor 14 of each of the five electrode units 12 (units 12-4, 12-8, 12-12, 12-16, and 12-20). In short, each dual-purpose signal line 19 short-circuits the dielectric element 15 and signal terminal 14-2 of each electrode unit 12 located in the same column group and connects them to an external device. It should be noted that these dual-purpose signal lines 19 can selectively transmit AC signals or receive temperature detection signals. This can be achieved by connecting each dual-purpose signal line 19 in series with a bidirectional switch 26 and coordinating the closing or opening of the grounding wire 18, which will be described in detail below.

[0070] The multi-path grounding wire 18 and the multi-path dual-purpose signal line 19 are both conductive traces embedded in the flexible circuit board 11. The flexible circuit board 11 is electrically connected to the first cable 13. The multi-path grounding wire 18 and the multi-path dual-purpose signal line 19 embedded in the flexible circuit board 11 are electrically connected to the corresponding wires (not shown) in the first cable 13.

[0071] The tumor electric field therapy system 100 of this embodiment includes at least one pair of the above-mentioned electrode plates 10, an adapter 20 electrically connected to the electrode plates 10, and an electric field generator 30 electrically connected to the adapter 20. The adapter 20 is connected between the electrode plates 10 and the electric field generator 30. The electric field generator 30 provides AC signals or DC signals to the dielectric elements 15 in the plurality of electrode units 12 of the electrode plates 10 via the adapter 20 and the dual-purpose signal line 19 of the electrode plates 10, and is used to receive temperature detection signals output by the temperature sensors 14 in the plurality of electrode units 12. The adapter 20 is configured to transmit the AC signal generated by the electric field generator 30 to the dual-purpose signal line 19 of the electrode plate 10, and is also configured to transmit the DC signal to the dual-purpose signal line 19 of the electrode plate and receive the temperature detection signal output from the multiple dual-purpose signal line 19 of the electrode plate 10.

[0072] Referring to Figures 3 and 4, the adapter 20 includes: a first controller 22, multiple sets of analog-to-digital converters 23 connected to the first controller 22, multiple sets of voltage-reducing resistors 24 corresponding to the multiple sets of analog-to-digital converters 23, multiple sets of grounding switches 25 and multiple sets of bidirectional switching switches 26, a first communication unit 27, multiple AC signal lines 28 respectively connected to the multiple sets of bidirectional switching switches 26, and a first specification 10 / 43 pages 14 CN 121288195 A connected to the first communication unit 27, the first controller 22 and the multiple sets of analog-to-digital converters 23.The power module 29 provides DC power (VCC) to the various electronic components of the adapter 20. The adapter 20 also includes multiple circuit lines (unlabeled). These multiple circuit lines (unlabeled) are electrically connected to the multiple ground lines 18 and multiple dual-purpose signal lines 19 within the flexible circuit board 11 of the corresponding electrode plate 10 via the first cable 13 of the respective electrode plate 10. The multiple circuit lines (unlabeled) include multiple AC signal lines 28 that transmit AC signals to the corresponding electrode 10 and are electrically connected to the multiplexed dual-purpose signal lines 19 in the flexible circuit board 11 of the corresponding electrode 10; multiple circuit lines (unlabeled) that are electrically connected one-to-one with the multiplexed dual-purpose signal lines 19 in the flexible circuit board 11 of the corresponding electrode 10 and are used to power each temperature sensor 14 of the electrode 10 or transmit the temperature detection signal of the electrode 10; and multiple circuit lines (unlabeled) that are electrically connected one-to-one with the multiple grounding lines 18 in the flexible circuit board 11 of the corresponding electrode 10. The number P of circuit lines electrically connected by the adapter 20 to one electrode 10 is equal to the sum of the number of rows M and the number of columns N of the electrode unit 12 of the electrode 10 plus 1; the number H of circuit lines electrically connected by the adapter 20 to X electrode 10s is equal to X times the number of circuit lines electrically connected to a single electrode 10, that is, H=XP=X×(M+N+1). The number of grounding switches 25 and the number of bidirectional switching switches 26 are related to the number of electrode plates 10. The number of grounding switches 25 is the same as the number of bidirectional switching switches 26; and not less than the number of electrode plates 10. Preferably, the number of grounding switches 25 and the number of bidirectional switching switches 26 are the same as the number of electrode plates 10. The following is a detailed description of the electrical connection between an electrode plate 10 with 20 electrode units 12 and the adapter 20.

[0073] Each group of grounding switches 25 is provided with multiple grounding switches 25. The multiple grounding switches 25 are respectively connected to the adapter 20 and electrically connected to the circuit lines (unlabeled) corresponding one-to-one with the multiple grounding wires 18 of the corresponding electrode plate 10, and are configured to control the conduction or disconnection of the multiple grounding wires 18. The circuit lines (unlabeled) that are electrically connected one-to-one with the multiple grounding wires 18 of the electrode plate 10 are grounded at the end near the grounding switch 25. The number of grounding switches 25 in each group of grounding switches 25 is related to the number of grounding wires 18 on the flexible circuit board 11 of the corresponding electrode piece 10; in this embodiment, the two are equal. As shown in Figure 3, in this embodiment, each group of grounding switches 25 is provided with multiple grounding switches 25, specifically five in this embodiment: a first grounding switch 25-1, a second grounding switch 25-2, a third grounding switch 25-3, a fourth grounding switch 25-4, and a fifth grounding switch 25-5. Each group of multiple grounding switches 25 controls the closing of the corresponding grounding wire 18 of a corresponding electrode piece 10.The first grounding switch 25-1 is used to control the opening or closing of the first grounding wire 18-1 of the corresponding electrode plate 10, and can cooperate with the corresponding set of bidirectional switching switches 26 to control the energization and de-energization of the temperature sensors 14 of the four electrode units 12 from electrode unit 12-1 to electrode unit 12-4 in the first row of the electrode plate 10; the second grounding switch 25-2 is used to control the opening or closing of the second grounding wire 18-2 of the electrode plate 10, and can cooperate with the corresponding set of bidirectional switching switches 26 to control the energization and de-energization of the temperature sensors 14 of the four electrode units 12 from electrode unit 12-5 to electrode unit 12-8 in the second row of the electrode plate 10; the third grounding switch 25-3 is used to control the opening or closing of the third grounding wire 18-3 of the electrode plate 10, and can cooperate with the corresponding set of bidirectional switching switches 26 to control the energization and de-energization of the temperature sensors 14 of the four electrode units 12 in the second row of the electrode plate 10; The temperature sensors 14 of each of the four electrode units 12 (12-9 to 12-12) in the third row of electrode plates 10 are energized and de-energized. A fourth grounding switch 25-4 controls the opening and closing of the fourth grounding wire 18-4 of the electrode plate 10, and can cooperate with the corresponding bidirectional switching switch 26 to control the energization and de-energization of the temperature sensors 14 of each of the four electrode units 12 (12-13 to 12-16) in the fourth row of electrode plates 10. A fifth grounding switch 25-5 controls the opening and closing of the fifth grounding wire 18-5 of the electrode plate 10, and can cooperate with the corresponding bidirectional switching switch 26 to control the energization and de-energization of the temperature sensors 14 of each of the four electrode units 12 (12-17 to 12-20) in the fifth row of electrode plates 10. The grounding switches 25 can be mechanical switches, such as relays. The grounding switches 25 can also be electronic switches, and each grounding switch 25 can be opened and closed by the first controller 22 of the adapter 20.

[0074] In this embodiment, all of the multiple sets of grounding switches 25 are electronic switches. The first controller 22 is communicatively connected to the multiple sets of grounding switches 25 and is used to sequentially and cyclically control the opening and closing states of multiple grounding switches 25 in each set of grounding switches 25, thereby sequentially and time-dividing each of the multiple grounding wires 18 of the corresponding electrode 10 and cooperating with the switching of the corresponding bidirectional switching switch 26, so as to sequentially and time-dividingly collect the temperature of the patient's body surface detected by all temperature sensors 14 on the electrode 10. The number of grounding switches 25 in each set is equal to the number of grounding wires 18 of the flexible circuit board 11 of the corresponding electrode 10.

[0075] Each set of bidirectional switching switches 26 is provided with multiple bidirectional switching switches 26. The multiple bidirectional switching switches 26 in each set are respectively connected to the adapter 20 and electrically connected to the multi-channel dual-purpose signal line 19 of the corresponding electrode 10.On the corresponding circuit lines (unlabeled). The number of bidirectional switching switches 26 in each group of bidirectional switching switches 26 is related to the number of dual-purpose signal lines 19 of the flexible circuit board 11 of the corresponding electrode sheet 10, which is greater than or equal to the number of dual-purpose signal lines 19 of the flexible circuit board 11 of the corresponding electrode sheet 10. In the embodiment shown in FIG3, the two are equal. Each bidirectional switching switch 26 has two ends labeled 1 and 2. The acquisition end 1 of multiple bidirectional switching switches 26 in the same group is electrically connected to the corresponding detection channel in the multiple detection channels of the corresponding group of analog-to-digital converters 23, and the input end 2 of each bidirectional switching switch 26 in the same group is electrically connected to the corresponding AC signal line 28. Each bidirectional switching switch 26 is configured to control the multiple dual-purpose signal lines 19 to connect to the corresponding AC signal line 28 to transmit AC signals or to connect to the corresponding detection channel of the corresponding group of analog-to-digital converters 23 to receive the temperature detection signal output by the temperature sensor 14.

[0076] As shown in FIG3, taking the electrical connection of an electrode plate 10 with an adapter 20 as an example, in this embodiment with 20 electrode units 12, the multiple bidirectional switching switches 26 are respectively a first bidirectional switching switch 26-1, a second bidirectional switching switch 26-2, a third bidirectional switching switch 26-3, and a fourth bidirectional switching switch 26-4. The multiple bidirectional switching switches 26 in the same group control the switching of a corresponding dual-purpose signal line 19 in the multi-channel dual-purpose signal line 19 of the same electrode plate 10 between transmitting AC power signals and transmitting temperature detection signals. Specifically, the first bidirectional switching switch 26-1 is used to control the switching of the first dual-purpose signal line 19-1 of the corresponding electrode plate 10 between transmitting AC signals and transmitting temperature detection signals, thereby controlling the switching between the conduction of each dielectric element 15 of the electrode units 12-1, 12-5, 12-9, 12-13, and 12-17 in the first column of the electrode plate 10 and the conduction of the signal terminals 14-2 of each temperature sensor 14 of the electrode units 12-1, 12-5, 12-9, 12-13, and 12-17 in the first column of the electrode plate 10, and cooperating with the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, fourth grounding switch 25-4, and fifth grounding switch 25-5 so that the first column of electrode units 12-1, 12-5, 12-9, and 12-17... 13. Electrode units 12-17 transmit AC signals to the patient or output temperature detection signals collected by the temperature sensors 14 of the electrode units 12 to the corresponding analog-to-digital converter 23; the second bidirectional switch 26-2 is used to control the switching of the second dual-purpose signal line 19-2 of the corresponding electrode pad 10 between transmitting AC signals and transmitting temperature detection signals, thereby controlling the electrode pad 10.The switching between the conduction of the dielectric elements 15 of electrode units 12-2, 12-6, 12-10, 12-14, and 12-18 in the second column group and the conduction of the signal terminals 14-2 of the temperature sensors 14 of electrode units 12-2, 12-6, 12-10, 12-14, and 12-18 in the second column group, and the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4, and the conduction of the signal terminals 14-2 of the temperature sensors 14 in the second column group, and the switching between these two functions ... 4. The fifth grounding switch 25-5, in conjunction with the second row of electrode units 12-2, 12-6, 12-10, 12-14, and 12-18, enables them to transmit AC signals to the patient or output temperature detection signals collected by the temperature sensors 14 of the electrode units 12 to the corresponding analog-to-digital converter 23; the third bidirectional switching switch 26-3 controls the switching of the third dual-purpose signal line 19-3 of the corresponding electrode pad 10 between transmitting AC signals and transmitting temperature detection signals, thereby controlling the third row of electrode pads 10. The switching between the conduction of each dielectric element 15 of electrode units 12-3, 12-7, 12-17, 12-15, and 12-19 and the conduction of the signal terminals 14-2 of each temperature sensor 14 of electrode units 12-3, 12-7, 12-11, 12-15, and 12-19 in the third column group, and the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch, is described in Instruction Manual 12 / 43. Page 16 CN 121288195 A The fifth grounding switch 25-4 and the fifth grounding switch 25-5 cooperate to enable the third column of electrode units 12-3, 12-7, 12-11, 12-15, and 12-19 to transmit AC signals to the patient or output temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23; the fourth bidirectional switching switch 26-4 is used to control the switching of the fourth dual-purpose signal line 19-4 of the corresponding electrode pad 10 between transmitting AC signals and transmitting temperature detection signals, thereby controlling the conduction of each dielectric element 15 of the electrode units 12-4, 12-8, 12-12, 12-16, and 12-20 in the fourth column of the electrode pad 10 and the conduction of the electrode units 12-4, 12-7, 12-11, 12-15, and 12-19 in the fourth column of the electrode pad 10. 8. The switching between the signal terminals 14-2 of each temperature sensor 14 in electrode units 12-12, 12-16, and 12-20 and the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch is connected.Grounding switch 25-4 and fifth grounding switch 25-5 cooperate to enable the fourth row of electrode units 12-4, 12-8, 12-12, 12-16, and 12-20 to transmit AC signals to the patient or output temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23. When the input terminal 2 of each group of bidirectional switching switches 26 is turned on and the acquisition terminal 1 is turned off, AC signals can be transmitted to the dielectric elements 15 of each electrode unit 12 of the corresponding electrode pad 10. When the acquisition terminal 1 of each group of bidirectional switching switches 26 is turned on and the input terminal 2 is turned off, it can cooperate with each grounding switch 25 in the corresponding group of grounding switches 25 to transmit the temperature detection signals collected by the temperature sensors 14 of each electrode pad 10 on the electrode pad 10 in a time-division manner. The aforementioned bidirectional switching switch 26 can be a mechanical switch, such as a relay. The bidirectional switching switch 26 can also be an electronic switch. The switching between the acquisition terminal 1 and the input terminal 2 of each bidirectional switching switch 26 can be controlled by the first controller 22 of the adapter 20.

[0077] In this embodiment, all sets of bidirectional switching switches 26 are electronic switches. The first controller 22 is communicatively connected to the multiple sets of bidirectional switching switches 26 and is used to control the multiple bidirectional switching switches 26 in each set of bidirectional switching switches 26 to switch between their respective acquisition terminals 1 and input terminals 2, and cooperate with the closing or opening of the corresponding grounding switch 25 to continuously monitor the temperature of the patient's body surface detected by all temperature sensors 14 on the electrode pad 10 or to transmit AC signals to the patient.

[0078] In this embodiment, each set of analog-to-digital converters 23 is electrically connected to the acquisition terminals 1 of the multiple bidirectional switching switches 26 in the corresponding set of bidirectional switching switches 26 through multiple circuit lines (unlabeled) in the adapter 20, and is configured to receive the temperature detection signal transmitted by the multi-channel dual-purpose signal line 19 of the corresponding electrode pad 10, and convert the temperature detection signal from an analog signal to a digital signal. Each group of analog-to-digital converters 23 includes multiple detection channels A, B, C, and D. Each detection channel A, B, C, and D is used to connect to a corresponding dual-purpose signal line 19 in the multi-channel dual-purpose signal line 19 via a corresponding bidirectional switch 26. The number of detection channels in each group of analog-to-digital converters 23 is related to the number of bidirectional switches 26 in the corresponding group. The number of detection channels in each group of analog-to-digital converters 23 is related to the number of column groups of electrode units 12 in the corresponding electrode sheet 10. Specifically, the number of detection channels in each group of analog-to-digital converters 23 is equal to the number of bidirectional switches 26 in the corresponding group of bidirectional switches 26, and is not less than the number of column groups of electrode units 12 in the corresponding electrode sheet 10. As shown in Figure 3, each group of analog-to-digital converters 23 includes a total of 4 detection channels A, B, C, and D, which are respectively the first detection channel A, the second detection channel B, the third detection channel C, the fourth detection channel D, the fifth detection channel D, the sixth detection channel D, the seventh detection channel D, the eighth detection channel D, the ninth detection channel D, the eleventh ...Four detection channels D. The first detection channel A is connected to the first dual-purpose signal line 19-1 via the acquisition terminal 1 of the first bidirectional switch 26-1; the second detection channel B is connected to the second dual-purpose signal line 19-2 via the acquisition terminal 1 of the second bidirectional switch 26-2; the third detection channel C is connected to the third dual-purpose signal line 19-3 via the acquisition terminal 1 of the third bidirectional switch 26-3; and the fourth detection channel D is connected to the fourth dual-purpose signal line 19-4 via the acquisition terminal 1 of the fourth bidirectional switch 26-4. Each detection channel A, B, C, and D is used to receive temperature detection signals acquired by the temperature sensor 14 of the corresponding dual-purpose signal line 19 connected to the electrode unit 12. Furthermore, each detection channel A, B, C, and D is connected via a corresponding voltage divider resistor 24 within the adapter 20 to a first power module 29, which provides detection voltage to that detection channel A, B, C, and D. The first power module 29 provides DC signals.

[0079] In this embodiment, the first communication unit 27 is configured to acquire digital signals output by multiple sets of analog-to-digital converters 23, and send the digital signals to the electric field generator 30. The electric field generator 30 is also configured to control and adjust the voltage, current, or power of the AC signal provided to the multiple electrode units 12 of the electrode sheet 10 according to the received digital signals. For example, when any of the received digital signals exceeds a preset threshold, it indicates that the temperature detected by at least one temperature sensor 14 in the electrode sheet 10 at the corresponding dielectric element 15 on the human body surface exceeds the preset threshold temperature (e.g., 41°C, 42°C, etc.). At this time, the voltage, current, or power of the AC signal output by the electric field generator 30 can be appropriately reduced to avoid the electrode unit 12 of the electrode sheet 10 from becoming too hot when the AC signal is applied, causing low-temperature burns to the patient's skin. The preset threshold temperature and the preset threshold can be determined according to human safety thresholds. The first communication unit 27 is controlled by the first controller 22 and serially transmits digital signals converted by multiple sets of analog-to-digital converters 23. In this embodiment, the preset temperature threshold can be a value within the range of 36℃-45℃.

[0080] Referring to Figures 4 and 5, in this embodiment, the first power module 29 is electrically connected to the second power module 31 of the electric field generator 30 and is configured to supply power to the first controller 22, multiple sets of analog-to-digital converters 23, and the first communication unit 27 of the adapter 20. Each electrode 10 is connected to the adapter 20 with a first connector 40, which is adapted to connect the corresponding electrode 10 to the adapter 20. As shown in Figure 1, the first connector 40 includes a first plug 41 located at the end of the first cable 13 away from the electrode 10 and a first socket 42 located on the adapter 20. The first plug 41 and the first socket42 is a press-type spring connector, that is, the first connector 40 connects the adapter 20 to the electrode plate 10 by means of a connector. Each first cable 13 has 4 wires that are electrically connected to the bidirectional switching switches 26 in the corresponding group of bidirectional switching switches 26 and 5 wires that are electrically connected to the grounding switches 25 in the corresponding group of grounding switches 25. That is, each first connector 40 is electrically connected to the corresponding group of bidirectional switching switches 26-1, 26-2, 26-3, 26-4 and the corresponding group of grounding switches 25-1, 25-2, 25-3, 25-4, 25-5 of the adapter 20 through 9 wires; and is connected to the electric field generator 30 through the corresponding AC signal line 28 of the adapter 20.

[0081] A second connector 50 is provided between the adapter 20 and the electric field generator 30. The second connector 50 is adapted to connect the electric field generator 30 to the adapter 20. The adapter 20 also includes a second cable 21 connected to the second connector 50. The second connector 50 includes a second plug 51 located at the end of the second cable 21 away from the first controller 22 and a second socket 52 located on the electric field generator 30. The second plug 51 and the second socket 52 are push-button spring connectors, that is, the second connector 50 connects the adapter 20 to the electric field generator 30 using a connector method. Each first connector 40, such as X1, Y1, X2, Y2, is connected to the second connector 50 via a corresponding AC signal line 28. Each first connector 40, such as X1, Y1, X2, Y2, is connected to a corresponding set of grounding switches 25 and a corresponding set of analog-to-digital converters 23. Specifically, each first connector 40 is simultaneously connected to the second connector 50 and the corresponding set of analog-to-digital converters 23 via a corresponding set of bidirectional switching switches 26. Taking four electrode plates 10 as an example, the second cable 21 has eight wires: four wires 1 to 4 that are electrically connected to the corresponding AC signal lines 28 and used to transmit AC signals; one wire 5 that is electrically connected to the data receiving line RX of the first communication unit 27; one wire 6 that is electrically connected to the data transmitting line TX of the first communication unit 27; one wire 7 that is electrically connected to the VCC power line of the first power module 29; and one wire 8 that is electrically connected to the GND line of the first power module 29.

[0082] The second connector 50 is connected to the first communication unit 27 through the data receiving line RX and the data transmitting line TX. The VCC pin of the second connector 50 is connected to the VVC power line of the first power module 29, and the GND pin of the second connector 50 is connected to the GND line of the first power module 29 and grounded. The VCC pin of the second connector 50 is also connected to the corresponding group of voltage regulators 24 and the corresponding group of analog-to-digital converters 23 through the VCC power line of the first power module 29.

[0083] Referring to FIG5, the electric field generator 30 includes: a second power supply module 31, a second controller 32, and an AC signal generator 34.The second communication unit 33 and a set of AC signal switches 35 are also included. The VCC pin of the second connector 50 is also electrically connected to the VCC power line of the second power module 31, and the GND pin of the second connector 50 is grounded through the GND line of the second power module 31. The second power module 31 is also connected to and powers the second controller 32 and the AC signal generator 34 respectively. The second communication unit 33 is electrically connected to the wire 5 of the second connector 50 through its data receiving line RX and to the wire 6 of the second connector 50 through its data transmitting line TX, thereby realizing information exchange between the electric field generator 30 and the adapter 20. The second controller 32 is also electrically connected to the second communication unit 33, the AC signal generator 34, and a set of AC signal switches 35. The second controller 32 is configured to control the opening and closing of each AC signal switch 35 in a set of AC signal switches 35 and adjust the relevant parameters of the AC signal applied by the AC signal generator 34 according to the relevant digital signals received from the adapter 20 by the second communication unit 33. The AC signal generator 34 is electrically connected to the AC signal transmission wires 1 to 4 of the second connector 50 through the set of AC signal switches 35. The set of AC signal switches 35 includes multiple AC signal switches 35, and the multiple AC signal switches 35 are arranged one-to-one with multiple electrode plates 10. Each AC signal switch 35 is electrically connected to a corresponding AC signal transmission wire 1, 2, 3, or 4 in the second connector 50 through an AC signal wiring 36, and is also electrically connected to the corresponding electrode plate 10 through the corresponding wires 1, 2, 3, or 4 of the second connector 50, so as to transmit an AC signal to each electrode plate 10. The AC signal generator 34 is electrically connected to the set of AC signal switches 35 through the set of AC signal wiring 36.

[0084] Specifically, the number of AC signal switches 35 in the electric field generator 30 is related to the number of electrode plates 10. In this embodiment, the number of AC signal switches 35 is equal to the number of electrode plates 10, and both are 4. The AC signal switches 35 include a first AC signal switch 35-1, a second AC signal switch 35-2, a third AC signal switch 35-3, and a fourth AC signal switch 35-4, which are electrically connected to the wires 1 to 4 of the second connector 50 through corresponding AC signal wiring 36. One end of the first AC signal switch 35-1 is electrically connected to the AC signal generator 34 through the first AC signal wiring 36-1 of the electric field generator 30, and the other end is electrically connected to the corresponding wire 1 for transmitting AC signals in the second connector 50 through the first AC signal wiring 36-1, and to the AC signal line 28 located at port X1 of the adapter 20 through the wire 1 of the second connector 50.AC signal line 28 is electrically connected to the first connector 40. The first connector 40, located at port X1 of adapter 20, is electrically connected to the corresponding electrode 10 to control whether the AC signal generator 34 transmits an AC signal to the electrode 10 electrically connected to port X1 of adapter 20. One end of the second AC signal switch 35-2 is electrically connected to the AC signal generator 34 through the second AC signal wiring 36-2 of the electric field generator 30, and the other end is electrically connected to the corresponding AC signal transmission wire 2 in the second connector 50 through a second AC signal wiring 36-2, and electrically connected to the AC signal line 28 located at port Y1 of adapter 20 through the wire 2 of the second connector 50. The AC signal line 28 located at port Y1 of adapter 20 is electrically connected to the first connector 40. The first connector 40 is electrically connected to the corresponding electrode 10 to control whether the AC signal generator 34 supplies an AC signal to the electrode 10 electrically connected to port Y1 of the adapter 20; one end of the third AC signal switch 35-3 is electrically connected to the AC signal generator 34 through the third AC signal wiring 36-3 of the electric field generator 30, and the other end is electrically connected to the corresponding AC signal transmission wire 3 in the second connector 50 through a third AC signal wiring 36-3, and is electrically connected to the AC signal line 28 at port X2 of the adapter 20 through the wire 3 of the second connector 50; the AC signal line 28 at port X2 of the adapter 20 is electrically connected to the first connector 40; and the first connector 40 at port X2 of the adapter 20 is electrically connected to the corresponding electrode 10 to control the AC signal generator 34. 4. Whether to supply AC signal to electrode 10 electrically connected to port X2 of adapter 20; one end of the fourth AC signal switch 35-4 is electrically connected to AC signal generator 34 through the fourth AC signal wiring 36-4 of electric field generator 30, and the other end is electrically connected to the corresponding wire 4 for transmitting AC signal in second connector 50 through a fourth AC signal wiring 36-4, and is electrically connected to AC signal line 28 at port Y2 of adapter 20 through wire 4 of second connector 50, AC signal line 28 at port Y2 of adapter 20 is electrically connected to first connector 40, and first connector 40 at port Y2 of adapter 20 is electrically connected to the corresponding electrode 10, so as to control whether AC signal generator 34 supplies AC signal to electrode 10 electrically connected to port Y1 of adapter 20.

[0085] The working principle of tumor electric field therapy system 100 of this embodiment will be described in detail below with reference to Figures 3 to 5. Instruction manual, pages 15 / 43, 19 CN 121288195 A

[0086] Specifically, when it is necessary to detect the temperature of each electrode unit 12 of a certain electrode plate 10, the first control of the adapter 20...The second controller 32 of the converter 22 or the electric field generator 30 controls each of the multiple bidirectional switching switches 26 electrically connected to the electrode 10 to turn on its acquisition terminal 1 and turn off its input terminal 2, thereby disconnecting the AC signal applied to the electrode 10. Simultaneously, the first controller 22 of the converter 20 or the second controller 32 of the electric field generator 30 controls each of the grounding switches 25 electrically connected to the electrode 10 to turn on sequentially. At this time, the temperature detection signals collected by the temperature sensors 14 of each electrode unit 12 in each row of the electrode 10 can be collected sequentially and time-divided by the multiple detection channels A, B, C, and D of the analog-to-digital converter 23 corresponding to the electrode 10. Each detection channel A, B, C, and D of each group of analog-to-digital converters 23 collects only the temperature detection signals of the temperature sensors 14 of the corresponding electrode unit 12 in each row of the electrode 10 at any given time. These temperature detection signals can be characterized by voltage values. Only one of the five grounding switches 25 in the group corresponding to the electrode 10 can be on at any given time, while the other four are off. All four bidirectional switches 26 in the group corresponding to the analog-to-digital converter 23 are switched to their respective acquisition terminals 1, so that each dual-purpose signal line 19 of the electrode 10 is electrically connected to the corresponding detection channels A, B, C, and D of the corresponding group of analog-to-digital converters 23. With this configuration, the group of analog-to-digital converters 23 can acquire the voltage values ​​of the temperature sensors 14 of each electrode unit 12 in the same row group that are short-circuited to one of the grounding lines 18 corresponding to the on-circuit grounding switch 25.

[0087] Specifically, when the first grounding switch 25-1 is closed, and the second grounding switch 25-2, the third grounding switch 25-3, the fourth grounding switch 25-4, and the fifth grounding switch 25-5 are all open, and the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, and the fourth bidirectional switching switch 26-4 are all switched to their respective acquisition terminals 1, the temperature sensors 14 of the electrode units 12-1 to 12-4 in the first row group are energized, and the temperature sensors 14 of the electrode units 12-5 to 12-20 in the other row groups are de-energized. In this group of analog-to-digital converters 23, the first detection channel A short-circuits the temperature sensors 14 of the electrode units 12-1, 12-5, 12-9, 12-13, and 12-17. The signal terminal 14-2 is only grounded because the ground terminal 14-1 of the temperature sensor 14 of electrode unit 12-1 is connected to ground, while the ground terminals 14-1 of the temperature sensors 14 of electrode units 12-5, 12-9, 12-13, and 12-17 are all grounded.The circuit is open, and each electrode unit 12 is equipped with a diode 16 connected in series with the temperature sensor 14. The other temperature sensors 14 in the first row will not affect the resistance value of the temperature sensor 14 in electrode unit 12-1. Therefore, only the temperature sensor 14 of electrode unit 12-1 is effectively working on the first detection channel A of this group of analog-to-digital converters 23. The temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 of electrode unit 12-1. Similarly, the voltage value collected by the second detection channel B in this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-2. The voltage value collected by the third detection channel C in this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-3. The voltage value collected by the fourth detection channel D in this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-4.

[0088] When the second grounding switch 25-2 is closed, and the first grounding switch 25-1, the third grounding switch 25-3, the fourth grounding switch 25-4, and the fifth grounding switch 25-5 are all open, and the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, and the fourth bidirectional switching switch 26-4 are all switched to their respective acquisition terminals 1, the temperature sensors 14 of the electrode units 12-5 to 12-8 of the second row group are energized, and the electrode units 12-1 to 12-4 of the remaining row groups, as well as the electrode unit 1... When the temperature sensors 14 of electrode units 2-9 to 12-20 are de-energized, the first detection channel A of the analog-to-digital converter 23 short-circuits the signal terminals 14-2 of the temperature sensors 14 of electrode units 12-1, 12-5, 12-9, 12-13, and 12-17. Since only the ground terminal 14-1 of the temperature sensor 14 of electrode unit 12-5 is grounded, the temperature sensors 14 of electrode units 12-1, 12-9, 12-13, and 12-17 remain connected. (Instruction manual 16 / 43) Page 20 CN 121288195 A The grounding terminal 14-1 of the temperature sensor 14 is disconnected, and each electrode unit 12 is equipped with a diode 16 connected in series with the temperature sensor 14. The other temperature sensors 14 located in the second row will not affect the resistance value of the temperature sensor 14 in electrode unit 12-5. Therefore, only the temperature sensor 14 of electrode unit 12-5 is effectively operating on the first detection channel A of this group of analog-to-digital converters 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 in electrode unit 12-5. Similarly, the voltage value collected on the second detection channel B of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-5.The voltage value of temperature sensor 14 in electrode unit 12-6. The voltage value collected on the third detection channel C in this group of analog-to-digital converters 23 is the voltage value of temperature sensor 14 in electrode unit 12-7. The voltage value collected on the fourth detection channel D in this group of analog-to-digital converters 23 is the voltage value of temperature sensor 14 in electrode unit 12-8.

[0089] When the third grounding switch 25-3 is closed, and the first grounding switch 25-1, the second grounding switch 25-2, the fourth grounding switch 25-4, and the fifth grounding switch 25-5 are all open, and the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, and the fourth bidirectional switching switch 26-4 are all switched to their respective acquisition terminals 1, the temperature sensors 14 of electrode units 12-9 to 12-12 in the third row group are energized, while the temperature sensors 14 of electrode units 12-1 to 12-8 and electrode units 12-13 to 12-20 in the other rows are de-energized. The first detection channel A in the analog-to-digital converter 23 of this group short-circuits electrode units 12-1, 12-5, 12-9, 12-13, and 12-20. Since only the grounding terminal 14-1 of the temperature sensor 14 in electrode unit 12-9 is connected to ground, while the grounding terminals 14-1 of the temperature sensors 14 in electrode units 12-1, 12-5, 12-13, and 12-17 are disconnected, and each electrode unit 12 has a diode 16 connected in series with the temperature sensor 14, the remaining temperature sensors 14 in the third row will not affect the resistance value of the temperature sensor 14 in electrode unit 12-9. Therefore, only the temperature sensor 14 in electrode unit 12-9 is effectively operating on the first detection channel A of this group of analog-to-digital converters 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 in electrode unit 12-9. Similarly, the voltage value collected on the second detection channel B of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-10. The voltage value collected on the third detection channel C of the analog-to-digital converter 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-11. The voltage value collected on the fourth detection channel D of the analog-to-digital converter 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-12.

[0090] When the fourth grounding switch 25-4 is closed, the first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3 and the fifth grounding switch 25-5 are all open, and the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3 and the fourth bidirectional switching switch 26-4 are all switched to their respective acquisition terminals 1, and the electrodes of the fourth row group...Temperature sensors 14 in units 12-13 to electrode units 12-16 are powered on, while temperature sensors 14 in the remaining rows (electrode units 12-11 to 12-12 and 12-17 to 12-20) are de-powered. The first detection channel A in the analog-to-digital converter 23 of this group short-circuites the signal terminals 14-2 of the temperature sensors 14 in electrode units 12-1, 12-5, 12-9, 12-13, and 12-17. Since only the ground terminal 14-1 of the temperature sensor 14 in electrode unit 12-13 is connected to ground, while the ground terminals 14-1 of the temperature sensors 14 in electrode units 12-1, 12-5, 12-9, and 12-17 are disconnected, and each electrode unit 12 has a diode 16 connected in series with the temperature sensor 14, the remaining temperature sensors 14 in the fourth row will not affect the resistance value of the temperature sensor 14 in electrode unit 12-13. Therefore, only the temperature sensor 14 of electrode units 12-13 is effectively operating on the first detection channel A of this group of analog-to-digital converters 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 of electrode units 12-13. Similarly, the voltage value collected on the second detection channel B of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode units 12-14. The voltage value collected on the third detection channel C of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode units 12-15. The voltage value collected on the fourth detection channel D of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode units 12-16.

[0091] When the fifth grounding switch 25-5 is closed, the first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4 are all open, and the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, and the fourth bidirectional switching switch 26-4 are all switched to their respective acquisition terminals 1. The temperature sensors 14 of the electrode units 12-17 to 12-20 in the fifth row group are powered on, while the temperature sensors 14 of the electrode units 12-1 to 12-16 in the other rows are de-powered. The first detection channel A in the analog-to-digital converter 23 of this group short-circuites the signal terminals 14-2 of the temperature sensors 14 of the electrode units 12-1, 12-5, 12-9, 12-13, and 12-17. Since only the ground terminal 14-1 of the temperature sensor 14 of the electrode unit 12-17 is grounded, while the temperature sensor 14 of the electrode unit 12-17 is grounded, the signal terminal 14-2 of the temperature sensor 14 of the electrode unit 12-17 is grounded.The grounding terminal 14-1 of the temperature sensors 14 in electrode units 12-5, 12-9, and 12-13 is disconnected. Each electrode unit 12 has a diode 16 connected in series with the temperature sensor 14. The remaining temperature sensors 14 in the fifth row do not affect the resistance of the temperature sensor 14 in electrode unit 12-17. Therefore, only the temperature sensor 14 of electrode unit 12-17 is effectively operating on the first detection channel A of this group of analog-to-digital converters 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 in electrode unit 12-17. Similarly, the voltage value collected on the second detection channel B of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-18. The voltage value collected on the third detection channel C of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-19. The voltage value acquired on the fourth detection channel D of the analog-to-digital converter 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-20.

[0092] Therefore, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 can acquire the temperature detection signals of the temperature sensors 14 of all electrode units 12 of the electrode sheet 10 by controlling a set of bidirectional switching switches 26 and a set of grounding switches that are electrically connected to a certain electrode sheet 10. Similarly, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 of other electrode sheets 10 can be obtained.

[0093] The first controller 22, multiple sets of analog-to-digital converters 23, and multiple sets of bidirectional switching switches 26 can automatically perform operations through pre-programmed program code. For example, the first controller 22 first controls all bidirectional switching switches 26 in the corresponding set to switch to the acquisition terminal 1, so that the acquisition terminals 1 of these bidirectional switching switches 26 are all turned on and the input terminals 2 are all turned off, so that the dual-purpose signal lines 19 of the corresponding electrode plates 10 are electrically connected to the corresponding set of analog-to-digital converters 23. Then, it closes the first grounding switch 25-1 in the corresponding set of grounding switches 25, and opens the remaining second grounding switches 25-2 and third grounding switches 25 in the same set of grounding switches 25. -3. The fourth grounding switch 25-4 and the fifth grounding switch 25-5, during this period, the detection channels A, B, C, and D of the group of analog-to-digital converters 23 acquire the temperature detection signals of the temperature sensors 14 of the electrode units 12 in the first row of the corresponding electrode plates 10, convert them into digital signals, and store them in a separately set memory. Then, after a preset interval, the first controller 22 closes the second grounding switch 25-2 in the group of grounding switches 25, and disconnects the first grounding switch 25-1, the third grounding switch 25-3, the fourth grounding switch 25-4, and the fifth grounding switch 25-5 in the group of grounding switches 25.During this period, the detection channels A, B, C, and D of the analog-to-digital converter 23 acquire the temperature detection signals of each temperature sensor 14 of each electrode unit 12 located in the second row group. By sequentially and individually turning on each grounding switch 25 in the group, the temperature detection signals of all temperature sensors 14 located in each row group of the electrode plate 10 can be obtained. Similarly, this operation can be used to obtain the temperature detection signals of all temperature sensors 14 on at least one pair of electrode plates 10.

[0094] The tumor electric field therapy system 100 of this application can achieve real-time and comprehensive monitoring of the temperature of all electrode units 12 on the electrode sheet 10 without increasing the weight of the electrode sheet 10 or the number of wire cores of the first cable 13 electrically connected to the electrode sheet 10. It can then determine whether the electrode sheet 10 is qualified based on the obtained temperature detection signal; or determine whether the temperature sensor 14 of the electrode sheet 10 is faulty or abnormal based on the obtained temperature detection signal, and determine whether the electrode sheet 10 needs to be replaced based on the number of faulty or abnormal temperature sensors 14 obtained; or, if the electrode sheet is qualified, identify the electrode sheet type based on the obtained temperature detection signal; or, if the electrode sheet is qualified, determine whether the electrode unit 12 of the electrode sheet 10 is overheated based on the obtained temperature detection signal, and further control the alternating electrical signal applied to the electrode sheet 10 or the corresponding column of electrode units 12 of the electrode sheet 10, to avoid low-temperature burns to the patient's body surface during tumor treatment through the electrode sheet 10. Furthermore, the flexible circuit board 11 of the electrode sheet 10 of this application is electrically connected to the dielectric element 15 of the same electrode unit 12 and the signal terminal 14-2 of the temperature sensor 14 through the same dual-purpose signal line 19. This allows for the transmission of both AC signals and DC signals for temperature signal acquisition, as well as the acquired temperature detection signal, via the dual-purpose signal line 19. Simultaneously, it significantly reduces the number of conductive traces (grounding line 18, dual-purpose signal line 19) laid on it, reducing the wiring difficulty of the flexible circuit board 11, simplifying the manufacturing process, reducing the weight of the flexible circuit board 11, and lowering manufacturing costs. The electrode sheet 10 of this application can also switch between applying AC signals for tumor treatment and transmitting DC signals for temperature acquisition and transmitting the acquired temperature detection signal through a combination of a grounding switch 25 electrically connected to the grounding line 18 and a bidirectional switching switch 26 electrically connected to the dual-purpose signal line 19.

[0095] When it is necessary to apply an alternating current signal to the patient through each electrode unit 12 of a certain electrode pad 10, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls a set of grounding switches 25 corresponding to that electrode pad 10.All grounding switches 25 in the circuit are disconnected, and simultaneously, all bidirectional switching switches 26 in a set of bidirectional switching switches 26 corresponding to the electrode 10 are switched to their respective input terminals 2. This causes all acquisition terminals 1 of these bidirectional switching switches 26 to be disconnected and all input terminals 2 to be turned on, so that all dual-purpose signal lines 19 of the electrode 10 are electrically connected to an AC signal line 28 corresponding to the electrode 10 in the adapter 20, thereby transmitting AC signals to each electrode unit 12 of the electrode 10. When the temperature detection signals of the temperature sensors 14 of all electrode units 12 of the electrode 10 are much lower than the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 controls the AC signal generator 34 through its second controller 32. The generator continues to generate alternating current signals with either increased or constant voltage or current amplitude, which are then transmitted to the corresponding counter electrode 10 via an AC signal line 28 of the adapter 20, so that the counter electrode 10 continues to receive an alternating current signal. When the temperature detection signals of the temperature sensors 14 of all electrode units 12 of the detected electrode 10 are lower than but close to a preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 can reduce the voltage or current of the alternating current signal generated by the AC signal generator 34 via the second controller 32, thereby reducing the voltage or current of the alternating current signal applied to the counter electrode 10. When the temperature detection signal of the temperature sensor 14 of an electrode unit 12 of a detected electrode 10 is greater than the preset temperature threshold, the electric field generator 30 controls the AC signal switch electrically connected to the electrode 10 via the second controller 32. 35 is disconnected to stop applying an AC signal to the electrode 10; or the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 controls all bidirectional switches 26 in a set of bidirectional switches 26 electrically connected to the electrode 10 to switch from their input terminals 2 to their acquisition terminals 1, that is, controls all bidirectional switches 26 in a set of bidirectional switches 26 electrically connected to the electrode 10 to have their acquisition terminals 1 fully open and their input terminals 2 fully open, thereby stopping the application of an AC signal to the electrode 10; or, when the temperature detection signal of the temperature sensor 14 of an electrode unit 12 on a certain electrode 10 is detected to be greater than a preset temperature threshold, the second controller 32 of the electric field generator 30 controls the AC signal switch 35 electrically connected to the electrode 10 to continue to be open, and the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 controls all bidirectional switches 26 in a set of bidirectional switches 26 electrically connected to the electrode 10 to have their acquisition terminals 1 fully open and their input terminals 2 fully open, thereby stopping the application of an AC signal to the electrode 10; A bidirectional switch 26, electrically connected to the electrode unit 12 of the electrode plate 10, is switched from its input terminal 2 to its acquisition terminal 1. Simultaneously, the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 controls the electrode unit 12 whose temperature detection signal does not exceed a preset temperature threshold and whose temperature detection signal exceeds the preset temperature threshold.The input terminals 2 of the remaining bidirectional switching switches 26, which are electrically connected to electrode units 12 in different columns, remain electrically connected. This stops applying AC signals to all electrode units 12 in the column where the temperature detection signal of the electrode 12 exceeds a preset temperature threshold, and continues to apply AC signals to the remaining column electrode units 12 whose temperature detection signal does not exceed the preset temperature threshold. This achieves a control method for regional application of AC signals based on temperature detection signals in the tumor electric field therapy system 100. When applying AC signals, all grounding switches 25 are disconnected.

[0096] In this embodiment, the grounding switch 25, which is electrically connected to each of the multiple grounding lines 18 of the electrode plate 10, and the bidirectional switching switch 26, which is electrically connected to each of the multiple dual-purpose signal lines 19 of the electrode plate 10, are both located in the adapter 20. However, in other embodiments, the grounding switch 25, which is electrically connected to the grounding line 18, and the bidirectional switching switch 26, which is electrically connected to the dual-purpose signal line 19, may also be located on the electrode plate 10 or in the electric field generator 30, which will not be described in detail here. In addition, the analog-to-digital converter 23 located in the adapter 20 may also be located in the electric field generator 30 and directly controlled by the second controller 32.

[0097] This application also provides other embodiments of the electrode plate 10 and the adapter 20. The main difference between the various embodiments of the electrode plate 10 is the number of electrode units 12 and / or the electrical connection arrangement of the electrode units 12. The various embodiments of the adapter 20 are adapted to the electrode plate 10 in different embodiments. The main difference is the number of grounding switches 25 and bidirectional switching switches 26, which will be described separately below.

[0098] Referring to FIG6, the electrode sheet 10A of the second embodiment has 19 electrode units 12. The flexible circuit board 11A arranges these 19 electrode units 12 in five rows and four columns in electrical connection, wherein each of the four rows has 4 electrode units 12, and the remaining row has 3 electrode units 12. The electrode sheet 10A includes 5 grounding wires 18 and 4 dual-purpose signal lines 19. Each grounding wire 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group. Each dual-purpose signal line 19 is short-circuited to the dielectric element 15 of each electrode unit 12 in each column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals. The 5 grounding wires 18 of the electrode sheet 10A include a first grounding wire 18-1, a second grounding wire 18-2, a third grounding wire 18-3, a fourth grounding wire 18-4, and a fifth grounding wire 18-5. The first row group includes electrode units 12-1 to 12-4, the second row group includes electrode units 12-5 to 12-8, and so on.The third row group includes electrode units 12-9 to 12-12, the fourth row group includes electrode units 12-13 to 12-16, and the fifth row group includes electrode units 12-17 to 12-19. Specifically, the first grounding wire 18-1 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each of the four electrode units 12 from electrode unit 12-1 to electrode unit 12-4 in the first row group; the second grounding wire 18-2 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each of the four electrode units 12 from electrode unit 12-5 to electrode unit 12-6 in the second row group; the third grounding wire 18-3 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each of the four electrode units 12 from electrode unit 12-9 to electrode unit 12-12 in the third row group; the fourth grounding wire 18-4 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each of the four electrode units 12 from electrode unit 12-13 to electrode unit 12-16 in the fourth row group; and the fifth grounding wire 18-5 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each of the three electrode units 12 from electrode unit 12-17 to electrode unit 12-19 in the fifth row group. In short, each grounding wire 18 shorts and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in each row group.

[0099] The four dual-purpose signal lines 19 of the electrode sheet 10A include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, and a fourth dual-purpose signal line 19-4. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the five electrode units 12 (electrode units 12-1, 12-5, 12-9, 12-13, and 12-17) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the five electrode units 12 (electrode units 12-2, 12-6, 12-10, 12-14, and 12-18) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric element 15 of each of the five electrode units 12 (electrode units 12-3, 12-7, 12-11, 12-18), and the signal terminal 14-2 of their respective temperature sensors 14; (Instruction manual 20 / 43 pages 24 CN 121288195 A) The signal terminals 14-2 of the dielectric elements 15 and temperature sensors 14 of the five electrode units 12 (12-15 and 12-19) are connected simultaneously to the signal terminals 14-2 of the dielectric elements 15 and temperature sensors 14 of the four electrode units 12 (12-4, 12-8, 12-12, and 12-16).Terminal 14-2. In short, each dual-purpose signal line 19 shorts in parallel the signal terminals 14-2 of the dielectric elements 15 and the temperature sensors 14 of each electrode unit 12 located in the same column group and connects them to the adapter 20.

[0100] The adapter 20 of the first embodiment can be adapted to the electrode plate 10A of the second embodiment. The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3, the fourth grounding switch 25-4 and the fifth grounding switch 25-5 of the adapter 20 are electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, the third grounding wire 18-3, the fourth grounding wire 18-4 and the fifth grounding wire 18-5 of the electrode plate 10A respectively through the first connector 40. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, and the fourth bidirectional switching switch 26-4 on the adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, and the fourth dual-purpose signal line 19-4 of the electrode 10A respectively via the first connector 40. The tumor electric field therapy system formed by the electrode 10A, the adapter 20, and the electric field generator 30 operates in the same way as the aforementioned tumor electric field therapy system 100. When all grounding switches 25 are open and the input terminals 2 and acquisition terminals 1 of all bidirectional switching switches 26 are closed, all dual-purpose signal lines 19 and AC signal lines 28 are connected, and all electrode units 12 are connected to AC signals. When the acquisition terminals 1 and input terminals 2 of all bidirectional switching switches 26 are closed, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25.

[0101] Referring to FIG7, the electrode sheet 10B of the third embodiment has 18 electrode units 12. The flexible circuit board 11B arranges these 18 electrode units 12 in three rows and six columns in electrical connection, with each row having 6 electrode units 12. The electrode sheet 10B includes 3 grounding wires 18 and 6 dual-purpose signal lines 19. Each grounding wire 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group. Each dual-purpose signal line 19 is short-circuited to the dielectric element 15 of each electrode unit 12 in each column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals. The 3 grounding wires 18 of the electrode sheet 10B include a first grounding wire 18-1, a second grounding wire 18-2 and a third grounding wire 18-3. The first row group includes electrode units 12-1 to 12-6, the second row group includes electrode units 12-7 to 12-12, and the third row group includes electrode units 12-13 to 12-18. Specifically, the first grounding wire 18-1 is used to connect the first...The grounding terminal 14-1 of the temperature sensor 14 of each of the six electrode units 12 in the first row group (electrode units 12-1 to 12-6) is grounded. The second grounding wire 18-2 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each of the six electrode units 12 in the second row group (electrode units 12-7 to 12-12). The third grounding wire 18-3 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each of the six electrode units 12 in the third row group (electrode units 12-13 to 12-18). In short, each grounding wire 18 short-circuits and grounds the grounding terminal 14-1 of the temperature sensor 14 of all the electrode units 12 in the corresponding row group.

[0102] The six dual-purpose signal lines 19 of the electrode sheet 10B include the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, the fifth dual-purpose signal line 19-5, and the sixth dual-purpose signal line 19-6. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-1, 12-7, and 12-13) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-2, 12-8, and 12-14) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-3, 12-9, and 12-15) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-3, 12-9, and 12-15) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-1, 12-7, and 12-13) and the signal terminal 14-2 of their respective temperature sensors 14; [Instruction manual page 21 / 43, 25 CN 121288195 A] Each of the three electrode units 12 (electrode units 12-4, 12-10, and 12-16) has its dielectric element 15 and its signal terminal 14-2 of its temperature sensor 14 connected to it. One end of the fifth dual-purpose signal line 19-5 is simultaneously connected to the dielectric element 15 and the signal terminal 14-2 of the three electrode units 12 (electrode units 12-5, 12-11, and 12-17). One end of the sixth dual-purpose signal line 19-6 is simultaneously connected to the dielectric element 15 and the signal terminal 14-2 of the three electrode units 12 (electrode units 12-6, 12-12, and 12-18). In short, each dual-purpose signal line 19 short-circuits the dielectric element 15 and the signal terminal 14-2 of the temperature sensor 14 of each electrode unit 12 located in the corresponding column group and connects them to the adapter 20A.

[0103] Referring to Figure 9, the adapter 20A of the second embodiment is adapted to the electrode plate 10B of the third embodiment. The adapter 20A is provided with three grounding switches 25 (first grounding switch 25-1, second grounding switch 25-2, and third grounding switch 25-3) and six bidirectional switching switches 26 (first bidirectional switching switch 26-1, second bidirectional switching switch 26-2, third bidirectional switching switch 26-3, fourth bidirectional switching switch 26-4, fifth bidirectional switching switch 26-5, and sixth bidirectional switching switch 26-6). The first grounding switch 25-1, the second grounding switch 25-2, and the third grounding switch 25-3 are electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, and the third grounding wire 18-3 of the electrode plate 10B respectively through the first connector 40A of the second embodiment. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4, the fifth bidirectional switch 26-5, and the sixth bidirectional switch 26-6 on the adapter 20A are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, the fifth dual-purpose signal line 19-5, and the sixth dual-purpose signal line 19-6 on the electrode plate 10B respectively via the first connector 40A. The tumor electric field therapy system formed by electrode 10B, adapter 20A and electric field generator 30 works in the same way as the aforementioned tumor electric field therapy system 100. When all grounding switches 25 are off and the input terminals 2 of all bidirectional switching switches 26 are on and the acquisition terminals 1 are off, all dual-purpose signal lines 19 and AC signal lines 28 are on, and all electrode units 12 are connected to AC signals. When the acquisition terminals 1 of all bidirectional switching switches 26 are on and the input terminals 2 are off, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row can be obtained sequentially by turning on each grounding switch 25.

[0104] Referring to FIG8, the electrode 10C of the fourth embodiment is provided with 17 electrode units 12. In terms of electrical connection, the flexible circuit board 11C arranges these 17 electrode units 12 in three rows and six columns, wherein each of the two rows has 6 electrode units 12, and the remaining row has 5 electrode units 12. The electrode plate 10C includes three grounding wires 18 and six dual-purpose signal lines 19. Each grounding wire 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group. Each dual-purpose signal line 19 short-circuits the dielectric element 15 of each electrode unit 12 in the corresponding column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals. The three grounding wires 18 of the electrode plate 10C include a first grounding wire 18-1, a second grounding wire 18-2, and a third grounding wire 18-3. The first row group includes electrode units 12-1 to...The first row group includes electrode units 12-6, the second row group includes electrode units 12-7 to 12-12, and the third row group includes electrode units 12-13 to 12-18. Specifically, the first grounding wire 18-1 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each of the six electrode units 12 in the first row group (electrode units 12-1 to 12-6), the second grounding wire 18-2 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each of the six electrode units 12 in the second row group (electrode units 12-7 to 12-12), and the third grounding wire 18-3 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each of the five electrode units 12 in the third row group (electrode units 12-13 to 12-17). In short, each grounding wire 18 short-circuits and grounds the grounding terminals 14-1 of the temperature sensor 14 of all electrode units 12 in the corresponding row group.

[0105] The six dual-purpose signal lines 19 of the electrode sheet 10C include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, a fifth dual-purpose signal line 19-5 and a sixth dual-purpose signal line 19-6. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode unit 12-1, electrode unit 12-7, and electrode unit 12-13) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode unit 12-2, electrode unit 12-8, and electrode unit 12-14) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode unit 12-3, electrode unit 12-9, and electrode unit 12-15). And the signal terminals 14-2 of their respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is simultaneously connected to the dielectric elements 15 of the three electrode units 12 (electrode units 12-4, 12-10, and 12-16) and the signal terminals 14-2 of their respective temperature sensors 14; one end of the fifth dual-purpose signal line 19-5 is connected to the dielectric elements 15 of the three electrode units 12 (electrode units 12-5, 12-11, and 12-17) and the signal terminals 14-2 of their respective temperature sensors 14; one end of the sixth dual-purpose signal line 19-6 is connected to the dielectric elements 15 of the two electrode units 12 (electrode units 12-6 and 12-12) and the signal terminals 14-2 of their respective temperature sensors 14. In short, each dual-purpose signal line 19 will...Each dielectric element 15 and the signal terminal 14-2 of each temperature sensor 14 in the same column group of electrode units 12 are shorted in parallel and used to connect to the adapter 20A.

[0106] Referring to FIG9, the adapter 20A of the second embodiment can be adapted to the electrode plate 10C of the fourth embodiment. The first grounding switch 25-1, the second grounding switch 25-2 and the third grounding switch 25-3 of the adapter 20A are electrically connected to the first grounding wire 18-1, the second grounding wire 18-2 and the third grounding wire 18-3 of the electrode plate 10C respectively through the first connector 40A. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4, the fifth bidirectional switch 26-5, and the sixth bidirectional switch 26-6 on the adapter 20A are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, the fifth dual-purpose signal line 19-5, and the sixth dual-purpose signal line 19-6 on the electrode plate 10C respectively via the first connector 40A. The tumor electric field therapy system formed by electrode 10C, adapter 20A, and electric field generator 30 operates in the same way as the previous tumor electric field therapy system 100. When the input terminal 2 of all bidirectional switching switches 26 is turned on and the acquisition terminal 1 is turned off, all dual-purpose signal lines 19 and AC signal lines 28 are turned on, and all electrode units 12 are connected to AC signals. When the acquisition terminal 1 of all bidirectional switching switches 26 is turned on and the input terminal 2 is turned off, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25.

[0107] Referring to FIG10, the tumor electric field therapy system 100D of the fifth embodiment of this application is shown. The difference between it and the tumor electric field therapy system 100 described in FIG1 is that: in this embodiment, the electrode 10D of the fifth embodiment is electrically connected to the adapter 20 and the electric field generator 30 of the third embodiment. There are also 4 electrode 10Ds in this embodiment, which are respectively connected to the first socket 42 of the adapter 20 through the first plug 41D provided at the end of the first cable 13D. Each electrode plate 10D also includes multiple electrode units 12D that are both axially symmetrically arranged and centrally aligned, several connecting portions 111D located between adjacent electrode units 12, and wiring portions 112D electrically connected to the first cable 13D; however, the wiring portion 112D extends from an electrode unit 12 outwards from the electrode array (unlabeled) and is arranged perpendicular to a connecting portion 111D. The first cable 13D has 8 core wires.

[0108] The electrode units 12D of the electrode plate 10D have the same structure as the electrode units 12 in the aforementioned embodiment, the only difference being that the number of electrode units 12 in this embodiment is 13, and they are arranged in five rows and five columns in space. Specifically,The first and last rows each have two electrode units 12, located in the second and fourth columns respectively. The middle three rows each have three electrode units 12, located in the first, third, and fifth columns respectively. There are three electrode units 12 located at the center of the electrode array (unlabeled), specifically the three electrode units 12 located in the third column of the second row, the third column of the third row, and the third column of the third row. The remaining electrode units 12 are located on the periphery of the electrode array (unlabeled). In the outermost electrode units 12, adjacent electrode units 12 are connected by connecting parts 111D. The electrode units 12 in the second row and third column are connected to the adjacent electrode units 12 in the first and second rows via connecting parts 111D. The electrode units 12 in the fourth row and third column are connected to the adjacent electrode units 12 in the fourth and fifth rows via connecting parts 111D. The electrode units 12 in the third row and third column are also connected to the adjacent electrode units 12 in the row and column directions via connecting parts 111D. The outermost electrode units 12 are connected in pairs via connecting parts 111D to form an octagonal ring structure.

[0109] FIG11(A) is a modified embodiment of the electrode sheet 10D shown in FIG10. The electrode unit 12D' of the electrode sheet 10D' in this embodiment is the same as the electrode unit 12D of the electrode sheet 10D shown in FIG10 in terms of spatial arrangement, and the connection part 111D' connected to the electrode unit 12D' located in the center is also the same. The only difference is that: in this modified embodiment, the two adjacent electrode units 12D' located on the periphery of the electrode sheet 10D' are connected by the connection part 111D'; the two adjacent electrode units 12D' located on the periphery are disconnected and no connection part 111D' is provided. Specifically, the two electrode units 12D' in the first row are disconnected from each other, the two electrode units 12D' in the last row are disconnected from each other, the two electrode units 12D' in the first column of the second row and the two electrode units 12D' in the second column of the first row are disconnected from each other, the two electrode units 12D' in the first column of the third row and the first electrode unit of the fourth row are disconnected from each other, the two electrode units 12D' in the fifth column of the second row and the fifth electrode unit of the third row are disconnected from each other, and the two electrode units 12D' in the fifth column of the fourth row and the fourth electrode unit of the fifth row are disconnected from each other. A first gap D1' is formed between two electrode units 12D' in adjacent columns that are disconnected from each other, and a second gap D2' is formed between two electrode units 12D' in adjacent rows that are disconnected from each other. The setting of the first gap D1' and the second gap D2' can prevent the electrode sheet 10D' from wrinkling during application, which would affect the overall adhesion effect of the electrode sheet.

[0110] Similar to Figure 11(B), Figure 11(B) is also a modified embodiment of the electrode sheet 10D shown in Figure 10. In this embodiment, the electrode units 12D” of the electrode sheet 10D” are arranged in the same spatial manner as the electrode units 12D of the electrode sheet 10D shown in Figure 10. The only difference is that in this modified embodiment, the two electrode units 12D” in the first row of the electrode sheet 10D” are disconnected, the two electrode units 12D” in the last row are disconnected, the two electrode units 12D” in the first column of the second row and the two electrode units 12D” in the third column of the second row are disconnected, and the two electrode units 12D’ in the third column of the fourth row and the two electrode units 12D’ in the fifth column of the fourth row are disconnected.

[0111] FIG12 is a schematic diagram of the circuit connection between the electrode sheet 10D of the fifth embodiment of the tumor electric field therapy system 100D shown in FIG10 or its variant embodiments 10D', 10D" and the adapter 20 of the first embodiment shown in FIG1. ​​The circuit is described below using the electrode sheet 10D of the fifth embodiment as an example. In terms of electrical connection, the flexible circuit board 11D of the electrode sheet 10D arranges the 13 electrode units 12 in three rows and five columns, with each of the two rows having 5 electrode units 12 and the remaining row having 3 electrode units 12. The electrode sheet 10D includes 3 grounding lines 18 and 5 dual-purpose signal lines 19. Each grounding line 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group. Each dual-purpose signal line 19 is short-circuited to the dielectric element 15 of each electrode unit 12 in each column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals.

[0112] The three grounding wires 18 of the electrode sheet 10D are designated as the first grounding wire 18-1, the second grounding wire 18-2, and the third grounding wire 18-3. In the three rows of the electrode sheet 10D, the first row includes electrode units 12-1 to 12-5, the second row includes electrode units 12-6 to 12-10, and the third row includes electrode units 12-11 to 12-13. Specifically, the first grounding wire 18-1 is used to sense the temperature of each of the electrode units 12-1 to 12-5 in the first row. The grounding terminal 14-1 of the device 14 is grounded; the second grounding wire 18-2 is used to ground the grounding terminal 14-1 of the temperature sensors 14 of each electrode unit 12-6 to electrode unit 12-10 in the second row group; the third grounding wire 18-3 is used to ground the grounding terminal 14-1 of the temperature sensors 14 of each electrode unit 12-11 to electrode unit 12-13 in the third row group. In short, each grounding wire 18 short-circuits and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group.

[0113] The five dual-purpose signal lines 19 of the electrode sheet 10D include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-1, 12-6, and 12-11) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-2, 12-7, and 12-12) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to electrode units 12-3 and 12-8. Each of the three electrode units 12-13 has its own dielectric element 15 and its own temperature sensor 14 signal terminal 14-2. One end of the fourth dual-purpose signal line 19-4 is simultaneously connected to the dielectric element 15 and the signal terminal 14-2 of the respective temperature sensor 14 of the two electrode units 12-4 and 12-9. One end of the fifth dual-purpose signal line 19-5 is simultaneously connected to the dielectric element 15 and the signal terminal 14-2 of the respective temperature sensor 14 of the two electrode units 12-5 and 12-10. In short, each dual-purpose signal line 19 short-circuits the dielectric element 15 and the signal terminal 14-2 of the respective temperature sensor 14 of each electrode unit 12 located in the same column group and connects them to the adapter 20B.

[0114] Referring to FIG14, the adapter 20B of the third embodiment is adapted to the electrode plate 10D of the fifth embodiment. The adapter 20B is provided with three grounding switches 25 (first grounding switch 25-1, second grounding switch 25-2 and third grounding switch 25-3) and six bidirectional switching switches 26 (first bidirectional switching switch 26-1, second bidirectional switching switch 26-2, third bidirectional switching switch 26-3, fourth bidirectional switching switch 26-4 and fifth bidirectional switching switch 26-5). The first grounding switch 25-1, the second grounding switch 25-2 and the third grounding switch 25-3 on the adapter 20B are electrically connected to the first grounding wire 18-1, the second grounding wire 18-2 and the third grounding wire 18-3 of the electrode plate 10D respectively through the first connector 40B. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4, and the fifth bidirectional switch 26-5 on the adapter 20B are connected to the first dual-purpose signal line 19-1 and the second bidirectional switch 26-5 on the electrode plate 10D respectively via the first connector 40B.Dual-purpose signal lines 19-2, 19-3, 19-4, and 19-5 are electrically connected in a one-to-one correspondence. The tumor electric field therapy system formed by electrode pads 10D, adapter 20B, and electric field generator 30 operates in the same way as the aforementioned tumor electric field therapy system 100. When the input terminals 2 of all bidirectional switching switches 26 are turned on and the acquisition terminals 1 are turned off, all dual-purpose signal lines 19 are connected to AC signal lines 28, and all electrode units 12 are connected to AC signals. When all grounding switches 25 are turned off and the acquisition terminals 1 of all bidirectional switching switches 26 are turned on and the input terminals 2 are turned off, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25 in sequence.

[0115] Referring to FIG13, the electrode sheet 10E of the sixth embodiment has 13 electrode units 12, just like the electrode sheet 10D of the fifth embodiment. However, the specific circuit layout is different. The flexible circuit board 11E of the electrode sheet 10E also arranges these 13 electrode units 12 in three rows and five columns in electrical connection. However, each of the two rows has 4 electrode units 12, and the remaining row has 5 electrode units 12. The electrode sheet 10E also includes 3 grounding lines 18 and 5 dual-purpose signal lines 19. Each grounding line 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group. Each dual-purpose signal line 19 is short-circuited to the dielectric element 15 of each electrode unit 12 in the same column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals. The three grounding wires 18 of the electrode sheet 10E include a first grounding wire 18-1, a second grounding wire 18-2, and a third grounding wire 18-3. The first row group includes electrode units 12-1 to 12-4, the second row group includes electrode units 12-5 to 12-8, and the third row group includes electrode units 12-9 to 12-13. Specifically, the first grounding wire 18-1 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-1 to 12-4 in the first row group; the second grounding wire 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-5 to 12-8 in the second row group; and the third grounding wire 18-3 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-9 to 12-13 in the third row group. In short, each path connects to the ground wire 18 on page 25 / 43 of the instruction manual (CN 121288195 A) to short-circuit and ground the grounding terminal 14-1 of the temperature sensor 14 of all electrode units 12 in the corresponding row group.

[0116] The five dual-purpose signal lines 19 of the electrode sheet 10E include the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, and...The third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode unit 12-1, electrode unit 12-5, and electrode unit 12-9) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode unit 12-2, electrode unit 12-6, and electrode unit 12-10) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the electrode unit 12... -3, electrode units 12-7, and electrode units 12-11 each have their respective dielectric elements 15 and signal terminals 14-2 of their respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is simultaneously connected to the dielectric elements 15 and signal terminals 14-2 of the respective temperature sensors 14 of the three electrode units 12-4, 12-8, and 12-12; one end of the fifth dual-purpose signal line 19-5 is connected to the dielectric element 15 and signal terminal 14-2 of the temperature sensor 14 of electrode unit 12-13. In short, each dual-purpose signal line 19 short-circuits the dielectric elements 15 and signal terminals 14-2 of the respective temperature sensors 14 of each electrode unit 12 located in the same column group and connects them to the adapter 20B.

[0117] Referring to FIG. 14, the adapter 20B of the third embodiment can be adapted to the electrode plate 10E of the sixth embodiment. The first grounding switch 25-1, the second grounding switch 25-2, and the third grounding switch 25-3 on the adapter 20B are electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, and the third grounding wire 18-3 of the electrode plate 10E respectively through the first connector 40B. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 on the adapter 20B are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5 of the electrode plate 10E respectively through the first connector 40B.

[0118] The tumor electric field therapy system formed by the electrode pads 10E, the adapter 20B, and the electric field generator 30 operates in the same manner as the aforementioned tumor electric field therapy system 100. When all grounding switches 25 are open and the input terminals 2 of all bidirectional switching switches 26 are closed and the acquisition terminals 1 are open, all dual-purpose signal lines 19 and AC signal lines 28 are connected, and all electrode units 12 are connected to AC signals. When the acquisition terminals 1 of all bidirectional switching switches 26 are closed and the input terminals 2 are closed, each grounding switch 25 is sequentially turned on to allow for...The temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group are obtained.

[0119] Referring to FIG15, the electrode sheet 10F of the seventh embodiment has 13 electrode units 12, just like the electrode sheet 10D of the sixth embodiment. However, the specific circuit layout is different. The flexible circuit board 11F of the electrode sheet 10F arranges these 13 electrode units 12 in four rows and four columns in electrical connection. Each of the three rows has 4 electrode units 12, and the remaining row has 1 electrode unit 12. The electrode sheet 10F includes 4 grounding lines 18 and 4 dual-purpose signal lines 19. Each grounding line 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group. Each dual-purpose signal line 19 is short-circuited to the dielectric element 15 of each electrode unit 12 in a corresponding column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals. The four grounding wires 18 of the electrode sheet 10F include a first grounding wire 18-1, a second grounding wire 18-2, a third grounding wire 18-3, and a fourth grounding wire 18-4. The first row group includes electrode units 12-1 to 12-4, the second row group includes electrode units 12-5 to 12-8, the third row group includes electrode units 12-9 to 12-12, and the fourth row group includes electrode unit 12-13. Specifically, the first grounding wire 18-1 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-1 to electrode unit 12-4 in the first row group; the second grounding wire 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-5 to electrode unit 12-8 in the second row group; the third grounding wire 18-3 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-9 to electrode unit 12-12 in the third row group; and the fourth grounding wire 18-4 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of electrode unit 12-13 in the fourth row group. In short, each grounding wire 18 short-circuits and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group.

[0120] The four dual-purpose signal lines 19 of the electrode sheet 10F include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, and a fourth dual-purpose signal line 19-4. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the four electrode units 12 (electrode unit 12-1, electrode unit 12-5, electrode unit 12-9, and electrode unit 12-13) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the four electrode units 12 (electrode unit 12-1, electrode unit 12-5, electrode unit 12-9, and electrode unit 12-13) and the signal terminal 14-2 of their respective temperature sensors 14;Each of the three electrode units 12 (electrode units 12-2, 12-6, and 12-10) has its respective dielectric element 15 and the signal terminal 14-2 of its respective temperature sensor 14 connected to it. One end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric element 15 and the signal terminal 14-2 of the respective temperature sensor 14 of each of the three electrode units 12 (electrode units 12-3, 12-7, and 12-11). One end of the fourth dual-purpose signal line 19-4 is simultaneously connected to the dielectric element 15 and the signal terminal 14-2 of the respective temperature sensor 14 of each of the three electrode units 12 (electrode units 12-4, 12-8, and 12-12). In short, each dual-purpose signal line 19 short-circuits the dielectric element 15 and the signal terminal 14-2 of the respective temperature sensor 14 of each electrode unit 12 located in the same column group and connects them to the adapter 20C.

[0121] Referring to FIG17, the adapter 20C of the fourth embodiment is used to adapt to the electrode plate 10F. The adapter 20C is provided with four grounding switches 25 (first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3 and fourth grounding switch 25-4) and four bidirectional switching switches 26 (first bidirectional switching switch 26-1, second bidirectional switching switch 26-2, third bidirectional switching switch 26-3 and fourth bidirectional switching switch 26-4). The first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3 and fourth grounding switch 25-4 of the adapter 20C are electrically connected to the first grounding wire 18-1, second grounding wire 18-2, third grounding wire 18-3 and fourth grounding wire 18-4 of the electrode plate 10F in the third embodiment, respectively, through the first connector 40C. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, and the fourth bidirectional switching switch 26-4 on the adapter 20C are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, and the fourth dual-purpose signal line 19-4 respectively through the first connector 40C.

[0122] The working mode of the tumor electric field therapy system formed by the electrode sheet 10F, the adapter 20C, and the electric field generator 30 is the same as that of the aforementioned tumor electric field therapy system 100. When all grounding switches 25 are open and the input terminals 2 of all bidirectional switching switches 26 are on and the acquisition terminals 1 are off, all dual-purpose signal lines 19 are connected to the AC signal line 28, and all electrode units 12 are connected to the AC signal. When the acquisition terminals 1 of all bidirectional switching switches 26 are on and the input terminals 2 are off, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25.

[0123] Referring to Figure 16, the electrode sheet 10G of the eighth embodiment also has 13 electrode units 12, but the specific circuit layout is different. The flexible circuit board 11G of the electrode sheet 10G arranges these 13 electrode units 12 in four rows and four columns in electrical connection, with three rows each having 3 electrode units 12 and the remaining row having 4 electrode units 12. The electrode sheet 10G includes 4 grounding lines 18 and 4 dual-purpose signal lines 19. Each grounding line 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group. Each dual-purpose signal line 19 is short-circuited to the dielectric element 15 of each electrode unit 12 in the corresponding column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals. The 4 grounding lines 18 of the electrode sheet 10G include a first grounding line 18-1, a second grounding line 18-2, a third grounding line 18-3, and a fourth grounding line 18-4. The first row group includes electrode units 12-1 to 12-3, the second row group includes electrode units 12-4 to 12-6, the third row group includes electrode units 12-7 to 12-9, and the fourth row group includes electrode units 12-10 to 12-13. Specifically, the first grounding wire 18-1 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-1 to 12-3 in the first row group; the second grounding wire 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-4 to 12-6 in the second row group; the third grounding wire 18-3 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-7 to 12-9 in the third row group; and the fourth grounding wire 18-4 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-10 to 12-13 in the fourth row group. In short, each grounding wire 18 short-circuits and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group.

[0124] The four dual-purpose signal lines 19 of the electrode sheet 10G include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, and a fourth dual-purpose signal line 19-4. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the four electrode units 12 (electrode unit 12-1, electrode unit 12-4, electrode unit 12-7, and electrode unit 12-10) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element of each of the four electrode units 12 (electrode unit 12-2, electrode unit 12-5, electrode unit 12-8, and electrode unit 12-11).The first dual-purpose signal line 19-3 connects to the dielectric element 15 of each of the four electrode units 12 (electrode units 12-3, 12-6, 12-9, and 12-12) and the signal terminal 14-2 of their respective temperature sensors 14. The second dual-purpose signal line 19-4 connects to the dielectric element 15 of electrode unit 12-13 and the signal terminal 14-2 of its temperature sensor 14. In short, each dual-purpose signal line 19 short-circuits the dielectric element 15 and the signal terminal 14-2 of the respective temperature sensors 14 of each electrode unit 12 located in the same column group and connects them to the adapter 20C.

[0125] Referring to FIG17, the adapter 20C is adapted to the electrode plate 10G. The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4 on the adapter 20C are electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, the third grounding wire 18-3, and the fourth grounding wire 18-4 of the electrode plate 10G respectively through the first connector 40C. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, and the fourth bidirectional switching switch 26-4 on the adapter 20C are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, and the fourth dual-purpose signal line 19-4 respectively through the first connector 40C.

[0126] The tumor electric field therapy system formed by the electrode sheet 10G, the adapter 20C and the electric field generator 30 operates in the same way as the aforementioned tumor electric field therapy system 100. When all grounding switches 25 are open and the input terminals 2 of all bidirectional switching switches 26 are on and the acquisition terminals 1 are off, all dual-purpose signal lines 19 and AC signal lines 28 are on, and all electrode units 12 are connected to AC signals. When the acquisition terminals 1 of all bidirectional switching switches 26 are on and the input terminals 2 are off, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25.

[0127] Referring to Figures 18 and 19, this application also provides another tumor treatment system 100H. The main difference between the tumor treatment system 100H and the previous tumor treatment system 100 is the different electrode sheets. The electrode sheet 10H of the ninth embodiment has 9 electrode units 12. In terms of spatial arrangement, the 9 electrode units 12 are arranged in a three-row, three-column array. In terms of electrical connection, the flexible circuit board 11H of the electrode sheet 10H arranges these 9 electrode units 12 in two rows and five columns, with one row having 5 electrode units 12 and the other row having 4 electrode units 12. The electrode sheet 10H includes 2 grounding lines 18 and 5 dual-purpose signal lines 19. Each grounding line 18 has 2 grounding lines 18 and 5 dual-purpose signal lines 19.Grounding wire 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group. Each dual-purpose signal line 19 is used to short-circuit the dielectric element 15 of each electrode unit 12 and the signal terminal 14-2 of each temperature sensor 14 in each column group, for receiving temperature detection signals or transmitting AC signals. The two grounding wires 18 of the electrode sheet 10H are the first grounding wire 18-1 and the second grounding wire 18-2. In the two rows of the electrode sheet 10H, the first row group includes electrode units 12-1 to 12-5, and the second row group includes electrode units 12-6 to 12-9. Specifically, the first grounding wire 18-1 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12-1 to 12-5 in the first row group; the second grounding wire 18-2 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12-6 to 12-9 in the second row group. In short, each grounding wire 18 shorts and grounds the grounding terminal 14-1 of the temperature sensor 14 of all electrode units 12 in the corresponding row group.

[0128] The five dual-purpose signal lines 19 of the electrode sheet 10H include the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the two electrode units 12, namely electrode unit 12-1 and electrode unit 12-6, and the signal terminal 14-2 of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the two electrode units 12-2 and electrode unit 12-7, and the signal terminal 14-2 of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric element 15 of each of the two electrode units 12-3 and electrode unit 12-8, and the signal terminal 14-2 of their respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is simultaneously connected to the dielectric element 15 of each of the two electrode units 12-4 and electrode unit 12-9, and the signal terminal 14-2 of their respective temperature sensors 14; one end of the fifth dual-purpose signal line 19-5 is simultaneously connected to the dielectric element 15 of electrode unit 12-5 and the signal terminal 14-2 of its temperature sensor 14. In short, each dual-purpose signal line 19 shorts in parallel the signal terminals 14-2 of the dielectric elements 15 and temperature sensors 14 of each electrode unit 12 located in the same column group and connects them to the adapter 20D.

[0129] Referring to FIG20, the adapter 20D of the fifth embodiment is adapted to the electrode plate 10H. The adapter 20D is provided with two terminals.The system includes a grounding switch 25 (first grounding switch 25-1, second grounding switch 25-2) and five bidirectional switching switches 26 (first bidirectional switching switch 26-1, second bidirectional switching switch 26-2, third bidirectional switching switch 26-3, fourth bidirectional switching switch 26-4, and fifth bidirectional switching switch 26-5). The first grounding switch 25-1 and the second grounding switch 25-2 on the adapter 20D are electrically connected, respectively, to the first grounding wire 18-1 and the second grounding wire 18-2 of the electrode plate 10H via the first connector 40D in the fifth embodiment. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4, and the fifth bidirectional switch 26-5 of the adapter 20D are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5 respectively via the first connector 40D.

[0130] The tumor electric field therapy system formed by the electrode sheet 10H, the adapter 20D, and the electric field generator 30 operates in the same way as the aforementioned tumor electric field therapy system 100. When all grounding switches 25 are off and the input terminals 2 of all bidirectional switching switches 26 are on and the acquisition terminals 1 are off, all dual-purpose signal lines 19 and AC signal lines 28 are on, and all electrode units 12 are connected to AC signals. When the acquisition terminals 1 of all bidirectional switching switches 26 are on and the input terminals 2 are off, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row can be obtained sequentially by turning on each grounding switch 25.

[0131] Referring to FIG21, the electrode sheet 10J of the tenth embodiment is also provided with 9 electrode units 12. In terms of electrical connection, the flexible circuit board 11J of the electrode sheet 10J arranges these 9 electrode units 12 in three rows and three columns, with 3 electrode units 12 in each row. The electrode plate 10J includes three grounding wires 18 and three dual-purpose signal lines 19. Each grounding wire 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the corresponding row group. Each dual-purpose signal line 19 is short-circuited to the dielectric element 15 of each electrode unit 12 in the corresponding column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals. The three grounding wires 18 of the electrode plate 10J are the first grounding wire 18-1, the second grounding wire 18-2, and the third grounding wire 18-3. In the three rows of the electrode plate 10J, the first row group includes electrode units 12-1 to 12-3, the second row group includes electrode units 12-4 to 12-6, and the third row group includes electrode units 12-7 to 12-9. Specifically, the first grounding wire 18-1 is used to ground the electrode units 12-1 to 12-3 in the first row group.Each temperature sensor 14 has its grounding terminal 14-1 grounded. The second grounding wire 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-4 to electrode unit 12-5 in the second row group. The third grounding wire 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-7 to electrode unit 12-9 in the third row group. In short, each grounding wire 18 short-circuits and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group.

[0132] The three dual-purpose signal lines 19 of the electrode sheet 10J include the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2 and the third dual-purpose signal line 19-3. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-1, 12-4, and 12-7) and the signal terminal 14-2 of their respective temperature sensors 14. One end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-2, 12-5, and 12-8) and the signal terminal 14-2 of their respective temperature sensors 14. One end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-3, 12-6, and 12-9) and the signal terminal 14-2 of their respective temperature sensors 14. In short, each dual-purpose signal line 19 short-circuits the dielectric element 15 and the signal terminal 14-2 of each electrode unit 12 located in the same column group and connects them to the adapter 20E.

[0133] Referring to FIG22, the adapter 20E of the sixth embodiment is adapted to the electrode plate 10J. The adapter 20E is provided with three grounding switches 25 (first grounding switch 25-1, second grounding switch 25-2 and third grounding switch 25-3) and three bidirectional switching switches 26 (first bidirectional switching switch 26-1, second bidirectional switching switch 26-2 and third bidirectional switching switch 26-3). The first grounding switch 25-1, the second grounding switch 25-2 and the third grounding switch 25-3 are electrically connected to the first grounding wire 18-1, the second grounding wire 18-2 and the third grounding wire 18-3 respectively through the first connector 40E of the sixth embodiment. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2 and the third bidirectional switching switch 26-3 of the adapter 20E are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2 and the third dual-purpose signal line 19-3 respectively through the first connector 40E.

[0134] The tumor electric field therapy system formed by electrode 10J, adapter 20E and electric field generator 30 operates in the same way as the aforementioned tumor electric field therapy system 100. When the input terminal 2 of all bidirectional switching switches 26 is turned on and the acquisition terminal 1 is turned off, all dual-purpose signal lines 19 and AC signal lines 28 are turned on, and all electrode units 12 are connected to AC signals. When the acquisition terminal 1 of all bidirectional switching switches 26 is turned on and the input terminal 2 is turned off, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25 in sequence.

[0135] In the tumor electric field therapy system of this application, the flexible circuit boards (11, 11A, 11B, 11C, 11D, 10D', 10D”, 11E, 11F, 11G, 11H, 10J) of each electrode sheet (10, 10A, 10B, 10C, 10D, 10D', 10D”, 11E, 11F, 11G, 11H) 11J) The electrode units 12 are divided into multiple rows and columns for electrical connection. The grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row is electrically connected to the same grounding wire 18. The dielectric element 15 and the signal terminal 14-2 of the temperature sensor 14 of each electrode unit 12 in the same column are short-circuited and then electrically connected to the same dual-purpose signal line 19. The adapter 20 is provided with multiple grounding switches 25 and multiple bidirectional switching switches 26. The electrode plates (10, 10A, 10B, 10C, 10D, 10D', 10D”, 10E, 10F, ... Each grounding wire 18 of 10G, 10H, and 10J is electrically connected to the corresponding grounding switch 25, and each dual-purpose signal line 19 is electrically connected to the corresponding bidirectional switching switch 26. The number of grounding switches 25 is equal to the number of grounding wires 18, and the number of bidirectional switching switches 26 is equal to the number of dual-purpose signal lines 19. Appropriate adapters are selected for each electrode to avoid idle grounding switches 25 and / or bidirectional switching switches 26, facilitating circuit control.

[0136] This application also provides some temperature detection methods and AC signal application control methods, which are described below using electrode 10 as an example.

[0137] This application embodiment provides an electrode temperature detection method, applied to the above-mentioned electrode 10 or tumor electric field therapy system 100, as shown in Figure 23, which includes the following steps:

[0138] Step 210: Control each bidirectional switching switch 26 electrically connected to each electrode unit 12 of the electrode 10 to disconnect the electrode. (See page 30 / 43 of the specification, CN 121288195 A) An alternating current signal is applied to the dielectric element 15 of each electrode unit 12 of the electrode sheet 10, and a direct current signal is simultaneously applied to the signal terminal 14-2 of the temperature sensor 14 of each electrode unit 12 of the electrode sheet 10;

[0139] Step 220: Sequentially turn on each grounding switch 25 electrically connected to the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 of the electrode sheet 10 in a time sequence to obtain the temperature detection signal of the temperature sensor 14 of each electrode unit 12 of the electrode sheet 10.

[0140] Step 210 specifically involves: controlling the bidirectional switching switch 26 electrically connected to each electrode unit 12 of the electrode sheet 10 to switch from the end electrically connected to the AC signal to the end electrically connected to the DC signal, that is, controlling the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch from its input terminal 2 to its acquisition terminal 1; or

[0141] controlling the bidirectional switching switch 26 electrically connected to each electrode unit 12 of the electrode sheet 10 to switch the dielectric element 15 of each electrode unit 12 of the electrode sheet 10 from the on state to the off state, and at the same time switching the signal terminal 14-2 of the temperature sensor 14 of each electrode unit 12 of the electrode sheet 10 from the off state to the on state.

[0142] The electrode temperature detection method of this application can quickly and accurately obtain the temperature of all electrode units of the electrode sheet; and can determine whether the temperature sensors of the electrode sheet are faulty, abnormal, or whether the electrode sheet is qualified and needs to be replaced based on the temperature detection signals of all temperature sensors of the electrode sheet; can also determine whether each electrode unit of the electrode sheet is overheated based on the temperature detection signals of all temperature sensors of the electrode sheet when all temperature sensors of the electrode sheet are normal, and then control the AC signal applied to the electrode sheet or each electrode unit of the electrode sheet; can also identify the electrode sheet type when the temperature detection signals of all temperature sensors of the electrode sheet are normal.

[0143] Referring to FIG24, this application embodiment also provides an AC signal application control method for tumor electric field therapy, which includes the above-mentioned steps 210 and 220, and after step 220, it further includes:

[0144] Step 260: When it is determined that the electrode 10 does not need to be replaced, the AC signal applied to each electrode unit 12 of the electrode 10 is controlled or adjusted according to the temperature detection signal of the temperature sensor 14 of each electrode unit 12 of the electrode 10.

[0145] Step 260 further includes controlling or adjusting the AC signal applied to each electrode unit 12 of the electrode sheet 10:

[0146] Step 261: When the temperature detection signals of each electrode unit 12 of the electrode sheet 10 are not exceeded by a preset temperature threshold, continue to apply AC signals to each electrode unit 12 of the electrode sheet 10; or

[0147] Step 262: When there is a temperature detection signal in all the temperature detection signals of the electrode units 12 of the electrode sheet 10 that exceeds the preset temperature threshold, stop applying AC signals to the electrode units 12 of the electrode sheet 10.

[0148] The step of stopping applying AC signals to the electrode units 12 of the electrode sheet 10 in step 262 includes stopping applying AC signals to the electrode units 12 of the electrode sheet 10.AC signals are applied to all electrode units 12 of electrode sheet 10, AC signals are stopped being applied to electrode units 12 in electrode sheet 10 whose temperature detection signals exceed a preset temperature threshold, and AC signals are stopped being applied to all electrode units 12 in the same column as the electrode units 12 in electrode sheet 10 whose temperature detection signals exceed the preset temperature threshold.

[0149] When AC signals are stopped being applied to electrode units 12 in electrode sheet 10 whose temperature detection signals exceed the preset temperature threshold, AC signals are still applied to electrode units 12 in electrode sheet 10 whose temperature detection signals do not exceed the preset temperature threshold.

[0150] When AC signals are stopped being applied to all electrode units 12 in the same column as the electrode units 12 in electrode sheet 10 whose temperature detection signals exceed the preset temperature threshold, AC signals are still applied to all electrode units 12 in electrode sheet 10 whose temperature detection signals do not exceed the preset temperature threshold and are in a different column from the electrode units 12 whose temperature detection signals exceed the preset temperature threshold. Instruction manual, pages 31 / 43, CN 121288195 A

[0151] The process of continuing to apply an AC signal to the electrode plate 10 as described in step 261 is as follows:

[0152] Step 263: When the temperature detection signal is much lower than the preset temperature threshold, continue to apply an AC signal to each electrode unit 12 of the electrode plate 10 by increasing the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode plate 10, or continue to apply an AC signal to each electrode unit 12 of the electrode plate 10 by keeping the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode plate 10 unchanged; or

[0153] Step 264: When the temperature detection signal approaches the preset temperature threshold, continue to apply the AC signal to each electrode unit 12 of the electrode sheet 10 in a manner that keeps the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode sheet 10 constant, or continue to apply the AC signal to each electrode unit 12 of the electrode sheet 10 in a manner that reduces the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode sheet 10.

[0154] Referring to Figure 25, this application also provides a signal control method for tumor electric field therapy, used for the above-mentioned electrode sheet 10. The method includes:

[0155] Step 310: Combining control of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the corresponding electrode sheet 10 to apply an AC signal to each electrode unit 12 of the electrode sheet 10 and executing step 320;

[0156] Step 320: Combining control of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to collect temperature detection signals of each electrode unit of the electrode sheet 10 in a row and executing step 330;

[0157] Step 330: Determining the combination control mode of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the electrode sheet 10 according to the collected temperature detection signals and executing step 340;

[0158] Step 340: Control the working state of each electrode unit 12 of the electrode sheet 10 according to the determined combination control method of grounding switch 25 and bidirectional switching switch 26.

[0159] The working state of each electrode unit 12 of the electrode sheet 10 in step 340 includes: stopping the application of AC signal and continuing to collect temperature detection signal, and stopping the collection of temperature detection signal and continuing to apply AC signal. Continuing to apply AC signal includes continuing to apply AC signal by increasing the voltage or current amplitude of the currently applied AC signal, continuing to apply AC signal by keeping the voltage or current amplitude of the currently applied AC signal unchanged, and continuing to apply AC signal by decreasing the voltage or current amplitude of the currently applied AC signal.

[0160] The working state of each electrode unit 12 of the electrode sheet 10 is determined by the temperature detection signal it collects. Each electrode unit 12 of the electrode sheet 10 is divided into different regions, and each electrode unit 12 in each region can be cyclically switched between applying AC signal and collecting temperature detection signal by the combination control of grounding switch 25 and bidirectional switching switch 26.

[0161] This application embodiment provides another method for detecting the temperature of an electrode sheet in a tumor electric field therapy system 100. Referring to FIG26, the temperature detection method includes:

[0162] Step 510: Disconnect the input of the AC signal to the electrode sheet 10, perform combined control of multiple grounding switches 25 and multiple bidirectional switching switches 26, and acquire the temperature detection signal of the temperature sensor 14 of the electrode sheet 10 corresponding to each combination;

[0163] Step 520: Sample and convert the temperature detection signal detected by each temperature sensor 14 in the electrode sheet 10 to obtain a digital temperature signal;

[0164] Step 530: Transmit the digital temperature signal to the electric field generator 30 of the tumor electric field therapy system 100 so that the electric field generator 30 can determine the temperature at the corresponding electrode unit 12 according to the digital temperature signal.

[0165] In step 510, “combined control of multiple grounding switches 25 and multiple bidirectional switching switches 26” specifically includes:

[0166] Step 511: Place all bidirectional switching switches 26 at the acquisition terminal 1 to connect the signal terminals 14-2 of the temperature sensors 14 of all electrode units 12 to the corresponding analog-to-digital converters 23;

[0167] Step 512: Sequentially close one of the multiple grounding switches 25 individually to acquire the temperature detection signals detected by the temperature sensors 14 of each electrode unit 12 in the corresponding row group.

[0168] In step 512, sequentially closing one of the multiple grounding switches 25 individually allows the detection channels of the analog-to-digital converter 23 to be electrically connected to each temperature sensor 14 in the row group corresponding to the closed grounding switch 25 to be activated.

[0169] Thus, the temperature detection signals of each temperature sensor 14 in each row group can be obtained sequentially, and then processed by the adapter 20 or the electric field generator 30 to obtain the temperature corresponding to all electrode units 12 on the electrode sheet 10; thereby making the temperature detection of the patient's body surface more comprehensive and accurate.

[0170] For the tumor electric field therapy system 100 of this application embodiment, temperature detection can also be performed on individual electrode units 12 as needed. The specific process of temperature detection for a certain electrode unit 12 of the electrode sheet 10 is as follows: disconnect the input of the AC signal, place the bidirectional switching switch 26 corresponding to the column group where the electrode unit 12 that needs to be measured individually is located at the acquisition end 1, and place the remaining bidirectional switching switches 26 at the input end 2; at the same time, turn on and ground the grounding switch 25 corresponding to the row group where the electrode unit 12 that needs to be measured individually is located, and turn off all the remaining grounding switches 25. Thus, the temperature detection signal of the temperature sensor 14 in the electrode unit 12 that needs to be measured individually can be sampled to obtain the temperature of the electrode unit 12. For example, if the electrode unit 12 requiring individual temperature measurement is electrode unit 12-1, then the corresponding AC signal switch 35 of the electric field generator 30 is turned off, and the first bidirectional switch 26-1 corresponding to electrode unit 12-1 is placed at the acquisition terminal 1. All other bidirectional switches (second bidirectional switch 26-2, second bidirectional switch 26-3, third bidirectional switch 26-3, and fourth bidirectional switch 26-4) are placed at the input terminal 2. Simultaneously, the first grounding switch 25-1 corresponding to electrode unit 12-1 is closed and grounded, and all remaining grounding switches (second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4) are turned off. Thus, the temperature of electrode unit 12-1 can be detected.

[0171] This application embodiment also provides another method for applying an alternating current signal for tumor electric field therapy, applied to the tumor electric field therapy system 100 described above. Referring to FIG27, the method for applying the alternating current signal includes:

[0172] Step 610: Determine the area where the electrode unit 12 to which the alternating current signal needs to be applied is located in the electrode sheet 10;

[0173] Step 611: Combine and control multiple grounding switches 25 and multiple bidirectional switching switches 26 electrically connected to the electrode sheet 10 to apply the alternating current signal.

[0174] The "combining and controlling multiple grounding switches 25 and multiple bidirectional switching switches 26 electrically connected to the electrode sheet 10" in step 611 specifically means:

[0175] Step 612: Disconnect all grounding switches 25 electrically connected to the electrode sheet 10;

[0176] Step 613: Determine the column group where the electrode unit 12 to which the alternating current signal needs to be applied is located, based on the area where the electrode unit 12 to which the alternating current signal needs to be applied is located;

[0177] Step 614: Determine the bidirectional switching switches 26 electrically connected to the electrode units 12 in the column groups where the electrode units 12 that need to be applied AC signals are located;

[0178] In step 610: Divide each of the four adjacent electrode units 12 in the electrode sheet 10 into a region, and the four electrode units 12 in each region correspond to a column group, connected to a dual-purpose signal line 19 corresponding to the same bidirectional switching switch 26.

[0179] Step 615: Control the bidirectional switching switches 26 electrically connected to the electrode units 12 that need to be applied AC signals to connect the electrode units 12 that need to be applied AC signals to the AC signal line 28 to apply AC signals; at the same time, control the remaining bidirectional switching switches 26 to disconnect the electrical connection between each electrode unit 12 in the region where AC signals do not need to be applied and the AC signal line 28 to stop applying AC signals.

[0180] In step 615, “connecting the electrode unit that needs to be applied with an AC signal to the AC signal line 28 to apply an AC signal and disconnecting the electrical connection between the electrode unit 12 in the area where no AC signal needs to be applied and the AC signal line 28 to stop applying the AC signal” is achieved by placing the bidirectional switching switch 26, which is electrically connected to the electrode unit 12 in the column group corresponding to the area in the electrode sheet 10 where an AC signal is to be applied, at its input terminal 2, and placing all the bidirectional switching switches 26, which are electrically connected to the electrode unit 12 in the remaining column groups, at the acquisition terminal 1.

[0181] The first controller 22 or electric field generator 30 in the adapter 20 of the tumor electric field therapy system 100 of this application embodiment is provided with a preset quantity threshold, a first preset temperature t1, a second preset temperature t2, and a preset temperature threshold t0, wherein the first preset temperature t1 is lower than the second preset temperature t2, and the second preset temperature t2 is lower than the preset temperature threshold t0.

[0182] This application embodiment also provides an AC signal application method based on temperature detection signal for the above-mentioned tumor electric field therapy system 100. Referring to FIG28, the application method includes:

[0183] Step 710: Start the tumor electric field therapy system 100;

[0184] Step 711: Combine the control of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the corresponding electrode sheet 10 to apply an AC signal to each electrode unit 12 of the electrode sheet 10;

[0185] Step 712: Combine the control of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to obtain the temperature of each electrode unit 12 of the electrode sheet 10;

[0186] Step 713: Determine whether there is an electrode unit 12 with a temperature exceeding a first preset temperature t1. If there is no electrode unit 12 with a temperature exceeding the first preset temperature t1, execute step 714. If there is an electrode unit 12 with a temperature exceeding the first preset temperature t1, execute step 714.When unit 12 is active, step 715 is executed;

[0187] Step 714: Continue to apply AC signals to each electrode unit 12 of electrode sheet 10 by increasing the voltage or current amplitude of the currently applied AC signal and return to step 712;

[0188] Step 715: Determine whether there is an electrode unit 12 with a temperature exceeding the second preset temperature t2; if there is no electrode unit 12 with a temperature exceeding the second preset temperature t2, execute step 716; if there is an electrode unit 12 with a temperature exceeding the second preset temperature t2, execute step 717;

[0189] Step 716: Continue to apply AC signals to each electrode unit 12 of electrode sheet 10 by keeping the voltage or current amplitude of the currently applied AC signal unchanged and return to step 712;

[0190] Step 717: Determine whether there is an electrode unit 12 whose temperature exceeds the preset temperature threshold t0. If there is no electrode unit 12 whose temperature exceeds the preset temperature threshold t0, proceed to step 718; if there is an electrode unit whose temperature exceeds the preset temperature threshold t0, proceed to step 719;

[0191] Step 718: Continue to apply an AC signal to all electrode units 12 of the electrode sheet 10 by reducing the voltage or current amplitude of the currently applied AC signal and return to step 712;

[0192] Step 719: Determine the number of overheated areas and proceed to step 720, wherein the overheated area is the area containing electrode units whose temperature exceeds the preset temperature threshold t0, and the non-overheated area is the area where the temperature of all electrode units does not exceed the preset temperature threshold t0;

[0193] Step 720: Determine whether the number of overheated areas exceeds a preset number threshold. If the number of overheated areas exceeds the preset number threshold, proceed to step 721; if the number of overheated areas does not exceed the preset number threshold, proceed to step 724;

[0194] Step 721: Stop applying AC signals to each electrode unit 12 of the electrode sheet 10 and execute step 722;

[0195] Step 722: Combine the control of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to obtain the temperature of each electrode unit 12 of the electrode sheet 10 and execute step 723;

[0196] Step 723: Determine whether there is an electrode unit 12 with a temperature exceeding the first preset temperature t1. If there is no electrode unit 12 with a temperature exceeding the first preset temperature t1 in the electrode sheet 10, return to step 711. If there is an electrode unit 12 with a temperature exceeding the first preset temperature t1 in the electrode sheet 10, return to step 722;

[0197] Step 724: Distinguish between the over-temperature area and the non-over-temperature area according to whether there is an electrode unit 12 with a temperature exceeding the preset temperature threshold t0. If the area is an over-temperature area, execute step 725. If the area is a non-over-temperature area, execute step 726.

[0198] Step 725: Stop applying AC signals to each electrode unit 12 in the overheated area and execute step 731;

[0199] Step 726: Determine whether the temperature of each electrode unit 12 in the non-overheated area does not exceed the first preset temperature t1. If the temperature of each electrode unit 12 in the non-overheated area does not exceed the first preset temperature t1, execute step 727. If there is a temperature in each electrode unit 12 in the non-overheated area that exceeds the first preset temperature t1, execute step 728;

[0200] Step 727: Continue applying AC signals to each electrode unit 12 in the non-overheated area of ​​the electrode sheet 10 by increasing the voltage or current amplitude of the currently applied AC signal and execute step 731;

[0201] Step 728: Determine whether the temperature of each electrode unit 12 in the non-overheated area does not exceed the second preset temperature t2. If the temperature of each electrode unit 12 in the non-overheated area does not exceed the second preset temperature t2, proceed to step 729. If any of the electrode units 12 in the non-overheated area exceeds the second preset temperature t2, proceed to step 730.

[0202] Step 729: Continue to apply an AC signal to each electrode unit 12 in the non-overheated area of ​​the electrode sheet 10 while maintaining the voltage or current amplitude of the currently applied AC signal unchanged, and proceed to step 731.

[0203] Step 730: Continue to apply an AC signal to each electrode unit 12 in the non-overheated area of ​​the electrode sheet 10 while reducing the voltage or current amplitude of the currently applied AC signal, and proceed to step 731.

[0204] Step 731: Combine the control of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the electrode plate 10 to reacquire the temperature of each electrode unit 12 of the electrode plate 10 and select to execute step 732 or step 734. The temperature of each electrode unit 12 of the electrode plate 10 includes the temperature of each electrode unit 12 in the over-temperature region and the temperature of each electrode unit 12 in the non-over-temperature region;

[0205] Step 732: Determine whether the temperature of each electrode unit 12 in the over-temperature region does not exceed the first preset temperature t1. If the temperature of each electrode unit 12 in the over-temperature region does not exceed the first preset temperature t1, execute step 733. If there is a temperature in each electrode unit 12 in the over-temperature region that exceeds the first preset temperature t1, return to step 731;

[0206] Step 733: Redetermine the region as a non-over-temperature region and execute step 734;

[0207] Step 734: Determine whether the temperature of each electrode unit 12 in the obtained non-overheated area does not exceed the first preset temperature t1. If the temperature of each electrode unit 12 in the non-overheated area does not exceed the first preset temperature t1, proceed to step 735. If any of the electrode units 12 in the non-overheated area exceeds the first preset temperature t1, proceed to step 736.

[0208] Step 735: Continue applying AC signals to each electrode unit 12 in the non-overheated area by increasing the voltage or current amplitude of the currently applied AC signal and return to step 712;

[0209] Step 736: Determine whether the temperature of each electrode unit 12 in the non-overheated area does not exceed the second preset temperature t2. If the temperature of each electrode unit 12 in the non-overheated area does not exceed the second preset temperature t2, execute step 737. If there is a temperature in each electrode unit 12 in the non-overheated area that exceeds the second preset temperature t2, execute step 738;

[0210] Step 737: Continue applying AC signals to each electrode unit 12 in the non-overheated area while keeping the voltage or current amplitude of the currently applied AC signal unchanged and return to step 712;

[0211] Step 738: Determine whether the temperature of each electrode unit 12 in the non-overheated area does not exceed the preset temperature threshold t0. If the temperature of each electrode unit 12 in the non-overheated area does not exceed the preset temperature threshold t0, execute step 739. When the temperature of each electrode unit 12 in the non-overheated area exceeds the preset temperature threshold t0, return to step 719;

[0212] Step 739: Continue to apply AC signal to each electrode unit 12 in the non-overheated area by reducing the voltage or current amplitude of the currently applied AC signal and return to step 712. Instruction manual, pages 35 / 43, 39, CN 121288195 A

[0213] Wherein, referring to Figure 22, the process of combining the control of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the corresponding electrode plate 10 in step 711 to apply AC signals to each electrode unit 12 of the electrode plate is specifically as follows:

[0214] Disconnect all grounding switches 25 electrically connected to the corresponding electrode plate 10, and simultaneously switch all bidirectional switching switches 26 electrically connected to the corresponding electrode plate 10 to the end that applies AC signals to each electrode unit 12; or

[0215] Disconnect all grounding switches 25 electrically connected to the corresponding electrode plate 10, and simultaneously switch all bidirectional switching switches 26 electrically connected to the corresponding electrode plate 10 to the end that connects each electrode unit 12 to the AC signal line 28; or

[0216] Disconnect all grounding switches 25 electrically connected to the corresponding electrode plate 10, and simultaneously switch all bidirectional switching switches 26 electrically connected to the corresponding electrode plate 10 to their respective input terminals 2.

[0217] The process of obtaining the temperature of each electrode unit 12 of the electrode plate 10 in steps 712, 722, and 731 is specifically as follows:

[0218] Control the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch all of its ends from the end that applies AC signals to each electrode unit 12 to the end that collects temperature data from each electrode unit 12, and close the switch in sequence at different times.The electrode unit 12 of the electrode sheet 10 is electrically connected to the grounding switch 25 to obtain the temperature of each electrode unit 12 of the electrode sheet 10; or

[0219] the bidirectional switching switch 26 electrically connected to the electrode sheet 10 is controlled to switch all of its input terminals 2 that apply AC signals to each electrode unit 12 to its acquisition terminals 1, and the grounding switches 25 electrically connected to the electrode units 12 of the electrode sheet 10 are closed sequentially in a time-sharing manner to obtain the temperature of each electrode unit 12 of the electrode sheet 10; or

[0220] the bidirectional switching switch 26 electrically connected to the electrode sheet 10 is controlled to switch the electrode sheet 10 from being electrically connected to the AC signal line 28 to being electrically connected to the corresponding analog-to-digital converter 23, and the grounding switches 25 electrically connected to the electrode units 12 of the electrode sheet 10 are closed sequentially in a time-sharing manner to obtain the temperature of each electrode unit 12 of the electrode sheet 10; or

[0221] The bidirectional switching switch 26, which is electrically connected to the electrode plate 10, switches each electrode unit 12 of the electrode plate 10 from transmitting AC signals to transmitting DC signals or temperature detection signals. The grounding switch 25, which is electrically connected to each electrode unit 12 of the electrode plate 10, is closed sequentially in a time-sharing manner to obtain the temperature of each electrode unit 12 of the electrode plate 10.

[0222] The first preset temperature in steps 713, 723, 726, 732, and 734 is 40℃-40.3℃, preferably 40.2℃. The second preset temperature in steps 715, 728, and 736 is 40.4℃ to 40.6℃, preferably 40.5℃; the preset temperature threshold in steps 717 and 738 is 41℃ to 41.5℃, preferably 41℃; the preset quantity threshold in step 720 is preferably 2.

[0223] The process of continuing to apply AC signals in steps 714, 716, 718, 727, 729, 730, 735, 737, and 739 is specifically as follows:

[0224] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 to which AC signals need to be continuously applied, and simultaneously control the bidirectional switching switch 26 electrically connected to the electrode unit 12 to which AC signals need to be continuously applied to conduct the AC signal transmission path electrically connected to the electrode unit 12 to which AC signals need to be continuously applied to continue applying AC signals to the electrode unit 12; or

[0225] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 to which AC signals need to be continuously applied, and simultaneously control the bidirectional switching switch 26 electrically connected to the electrode unit 12 to which AC signals need to be continuously applied to switch from its respective acquisition terminal 1 to its respective input terminal 2 to continue applying AC signals to the electrode unit 12 to which AC signals need to be continuously applied to continue applying AC signals; or

[0226] Disconnect the grounding switch 25 from the electrode unit 12 that needs to continue applying AC signals, and simultaneously control the connection with...The bidirectional switching switches 26 electrically connected to the electrode unit 12 that needs to continue to apply AC signals are each electrically connected to the AC signal line 28, so that AC signals continue to be applied to the electrode unit 12 that needs to continue to apply AC signals; or

[0227] the grounding switch 25 electrically connected to the electrode unit 12 that needs to continue to apply AC signals is disconnected, and at the same time, the bidirectional switching switches 26 electrically connected to the electrode unit 12 that needs to continue to apply AC signals are controlled to close their respective input terminals 2 and disconnect their acquisition terminals 1, so that AC signals continue to be applied to the electrode unit 12 that needs to continue to apply AC signals; or

[0228] the grounding switch 25 electrically connected to the electrode unit 12 that needs to continue to apply AC signals is disconnected, and at the same time, the bidirectional switching switches 26 electrically connected to the electrode unit 12 that needs to continue to apply AC signals are controlled to switch the electrode unit 12 from transmitting temperature detection signals to applying AC signals.

[0229] Increasing the voltage or current amplitude of the currently applied AC signal in steps 714, 727, and 735 specifically involves boosting the voltage of the currently applied AC signal by increasing the DC voltage amplitude by 0.03V per second.

[0230] Continuing to apply the AC signal by decreasing the voltage or current amplitude of the currently applied AC signal in steps 718, 730, and 739 specifically involves continuing to apply the AC signal by decreasing the voltage amplitude by 5V compared to the currently applied AC signal for 3 minutes.

[0231] The process of stopping the application of AC signals to each electrode unit 12 of the electrode plate 10 in step 721 specifically includes:

[0232] Controlling the bidirectional switching switch 26 electrically connected to the electrode plate 10 to disconnect the electrical connection between each electrode unit 12 of the electrode plate 10 and the AC signal line 28; or

[0233] Controlling the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch all of its ends that apply AC signals to each electrode unit 12 to its ends that collect temperature data from each electrode unit 12; or

[0234] Controlling the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch all of its input ends 2 that apply AC signals to each electrode unit 12 to its acquisition ends 1; or

[0235] Controlling the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch the electrode plate 10 from an electrical connection between each electrode unit 12 and the AC signal line 28 to an electrical connection between each electrode unit 12 and the corresponding analog-to-digital converter 23; or

[0236] The bidirectional switch 26, which is electrically connected to the electrode plate 10, controls the switching of each electrode unit 12 of the electrode plate 10 from transmitting AC signals to transmitting DC signals or temperature detection signals.

[0237] The process of stopping the application of AC signals to each electrode unit 12 in the over-temperature zone as described in step 725 specifically includes:

[0238] Controlling the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature zone to disconnect the electrical connection between each electrode unit 12 in the over-temperature zone and the AC signal line 28; or

[0239] Controlling the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature zone to switch all its ends that apply AC signals to each electrode unit 12 in the over-temperature zone to the ends that perform temperature acquisition on each electrode unit 12 in the over-temperature zone; or

[0240] Controlling the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature zone to switch all its input ends 2 that apply AC signals to each electrode unit 12 in the over-temperature zone to its acquisition ends 1; or

[0241] The bidirectional switching switch 26, which controls the electrical connection of each electrode unit 12 in the overheated area, switches each electrode unit 12 in the overheated area from being electrically connected to the AC signal line 28 to being electrically connected to the corresponding analog-to-digital converter 23; or

[0242] the bidirectional switching switch 26, which controls the electrical connection of each electrode unit 12 in the overheated area, switches each electrode unit 12 in the overheated area from transmitting AC signals to transmitting DC signals or temperature detection signals.

[0243] In the above application method, the tumor electric field therapy system 100 includes at least two pairs of electrode plates 10 to alternately apply alternating electric fields with different directions. Each electrode plate 10 can alternately switch between applying AC signals and transmitting temperature detection signals. The time periods for applying AC signals and applying DC signals for temperature acquisition of the electrode unit 12 of the same electrode plate 10 are staggered and do not overlap.

[0244] In the tumor electric field therapy system 100 of this application embodiment, the first controller 22 or electric field generator 30 in the adapter 20 is further provided with a third preset temperature t3, which is higher than the second preset temperature t2 but still lower than the preset temperature threshold t0. The third preset temperature t3 is closer to the preset temperature threshold t0 than the second preset temperature t2. This application embodiment also provides an AC signal control method based on temperature detection signals for the above-mentioned tumor electric field therapy system. Referring to Figure 29, the AC signal control method includes:

[0245] Step 810: Activating the tumor electric field therapy system 100;

[0246] Step 811: Combining the control of a grounding switch 25 and a bidirectional switching switch 26 electrically connected to the corresponding electrode pad 10 to apply an AC signal to each electrode unit 12 of the electrode pad 10;

[0247] Step 812: Combining the control of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the electrode pad 10 to obtain the temperature of each electrode unit 12 of the electrode pad 10;

[0248] Step 813: Determine if there is an electrode unit 12 with a temperature exceeding the first preset temperature t1. If there is no electrode unit 12 with a temperature exceeding the first preset temperature t1, proceed to step 814. If there is an electrode unit 12 with a temperature exceeding the first preset temperature t1, proceed to step 815.

[0249] Step 814: Continue to apply AC signals to each electrode unit 12 of the electrode sheet 10 by increasing the voltage or current amplitude of the currently applied AC signal and return to step 812.

[0250] Step 815: Determine if there is an electrode unit 12 with a temperature exceeding the second preset temperature t2. If there is no electrode unit 12 with a temperature exceeding the second preset temperature t2, proceed to step 816. If there is an electrode unit 12 with a temperature exceeding the second preset temperature t2, proceed to step 817.

[0251] Step 816: Continue to apply AC signals to each electrode unit 12 of the electrode sheet 10 by keeping the voltage or current amplitude of the currently applied AC signal unchanged and return to step 812.

[0252] Step 817: Determine if there is an electrode unit 12 with a temperature exceeding the third preset temperature t3. If there is no electrode unit 12 with a temperature exceeding the third preset temperature t3, proceed to step 818; if there is an electrode unit with a temperature exceeding the third preset temperature t3, proceed to step 819;

[0253] Step 818: Continue to apply AC signals to all electrode units 12 of the electrode sheet 10 by reducing the voltage or current amplitude of the currently applied AC signal and return to step 812;

[0254] Step 819: Determine if there is an electrode unit 12 with a temperature exceeding the preset temperature threshold t0. If there is no electrode unit 12 with a temperature exceeding the preset temperature threshold t0, proceed to step 820; if there is an electrode unit with a temperature exceeding the preset temperature threshold t0, proceed to step 821;

[0255] Step 820: Continue to apply AC signals to all electrode units 12 of the electrode sheet 10 by reducing the voltage or current amplitude of the currently applied AC signal and return to step 812;

[0256] Step 821: Determine the number of overheated areas and execute step 822, wherein the overheated area is the area containing electrode units whose temperature exceeds the preset temperature threshold t0, and the non-overheated area is the area where the temperature of all electrode units does not exceed the preset temperature threshold t0;

[0257] Step 822: Determine whether the number of overheated areas exceeds the preset number threshold. If the number of overheated areas exceeds the preset number threshold, execute step 823. If the number of overheated areas does not exceed the preset number threshold, execute step 826;

[0258] Step 823: Stop applying AC power signals to each electrode unit 12 of the electrode sheet 10 and execute step 824;

[0259] Step 824: Combine the control of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to obtain the specification page 38 / 43 42 CN.121288195 A The temperature of each electrode unit 12 of the electrode sheet 10 is measured and step 825 is executed;

[0260] Step 825: Determine whether there is an electrode unit 12 with a temperature exceeding the first preset temperature t1. If there is no electrode unit 12 with a temperature exceeding the first preset temperature t1 in the electrode sheet 10, return to step 811. If there is an electrode unit 12 with a temperature exceeding the first preset temperature t1 in the electrode sheet 10, return to step 824;

[0261] Step 826: Distinguish between the over-temperature region and the non-over-temperature region based on whether there is an electrode unit 12 with a temperature exceeding the preset temperature threshold t0. If the region is an over-temperature region, execute step 827. If the region is a non-over-temperature region, execute step 828;

[0262] Step 827: Stop applying AC power signals to each electrode unit 12 in the over-temperature region and execute step 835;

[0263] Step 828: Determine whether the temperature of each electrode unit 12 in the non-overheated area does not exceed the first preset temperature t1. If the temperature of each electrode unit 12 in the non-overheated area does not exceed the first preset temperature t1, proceed to step 829. If any of the electrode units 12 in the non-overheated area exceeds the first preset temperature t1, proceed to step 830.

[0264] Step 829: Continue to apply an AC signal to each electrode unit 12 in the non-overheated area of ​​the electrode sheet 10 by increasing the voltage or current amplitude of the currently applied AC signal and proceed to step 835.

[0265] Step 830: Determine whether the temperature of each electrode unit 12 in the non-overheated area does not exceed the second preset temperature t2. If the temperature of each electrode unit 12 in the non-overheated area does not exceed the second preset temperature t2, proceed to step 831. If any of the electrode units 12 in the non-overheated area exceeds the second preset temperature t2, proceed to step 832.

[0266] Step 831: Continue applying AC signals to each electrode unit 12 in the non-overheated area of ​​electrode sheet 10 while maintaining the voltage or current amplitude of the currently applied AC signal unchanged, and execute step 835;

[0267] Step 832: Determine whether there are any electrode units 12 in the non-overheated area whose temperature exceeds the third preset temperature t3. If the temperature of each electrode unit 12 in the non-overheated area does not exceed the third preset temperature t3, execute step 833. If there is a temperature in each electrode unit 12 in the non-overheated area that exceeds the third preset temperature t3, execute step 834;

[0268] Step 833: Continue applying AC signals to each electrode unit 12 in the non-overheated area of ​​electrode sheet 10 while reducing the voltage or current amplitude of the currently applied AC signal, and execute step 835;

[0269] Step 834: Continue to apply AC signals to each electrode unit 12 in the non-overheated area of ​​electrode sheet 10 in a manner that further reduces the voltage or current amplitude of the currently applied AC signal and proceed to step 835;

[0270] Step 835: Combine the control of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the electrode plate 10 to reacquire the temperature of each electrode unit 12 of the electrode plate 10 and select to execute step 836 or step 838. The temperature of each electrode unit 12 of the electrode plate 10 includes the temperature of each electrode unit 12 in the over-temperature region and the temperature of each electrode unit 12 in the non-over-temperature region;

[0271] Step 836: Determine whether the temperature of each electrode unit 12 in the over-temperature region does not exceed the first preset temperature t1. If the temperature of each electrode unit 12 in the over-temperature region does not exceed the first preset temperature t1, execute step 837. If there is a temperature in each electrode unit 12 in the over-temperature region that exceeds the first preset temperature t1, return to step 835;

[0272] Step 837: Redetermine the region as a non-over-temperature region and execute step 838;

[0273] Step 838: Determine whether the temperature of each electrode unit 12 in the obtained non-overheated area does not exceed the first preset temperature t1. If the temperature of each electrode unit 12 in the non-overheated area does not exceed the first preset temperature t1, execute step 839. If there is a temperature in each electrode unit 12 in the non-overheated area that exceeds the first preset temperature t1, execute step 840.

[0274] Step 839: Continue to apply AC signal to each electrode unit 12 in the non-overheated area by increasing the voltage or current amplitude of the currently applied AC signal and return to step 812.

[0275] Step 840: Determine whether the temperature of each electrode unit 12 in the obtained non-overheated area does not exceed the second preset temperature t2. If the temperature of each electrode unit 12 in the non-overheated area does not exceed the second preset temperature t2, execute step 841. If there is a temperature in each electrode unit 12 in the non-overheated area that exceeds the second preset temperature t2, execute step 842.

[0276] Step 841: Continue applying AC signals to each electrode unit 12 in the non-overheated area while maintaining the voltage or current amplitude of the currently applied AC signal, and return to step 812;

[0277] Step 842: Determine whether the temperature of each electrode unit 12 in the non-overheated area does not exceed the third preset temperature t3. If the temperature of each electrode unit 12 in the non-overheated area does not exceed the third preset temperature t3, execute step 843. If any of the electrode units 12 in the non-overheated area exceeds the third preset temperature t3, execute step 844;

[0278] Step 843: Continue applying AC signals to each electrode unit 12 in the non-overheated area while reducing the voltage or current amplitude of the currently applied AC signal, and return to step 812;

[0279] Step 844: Determine whether the temperature of each electrode unit 12 in the obtained non-overheated area does not exceed the preset temperature threshold t0. If the temperature of each electrode unit 12 in the non-overheated area does not exceed the preset temperature threshold t0, execute step 845. If there is a temperature in each electrode unit 12 in the non-overheated area that exceeds the preset temperature threshold t0, return to step 821.

[0280] Step 845: Continue to apply AC signals to each electrode unit 12 in the non-overheated area by further reducing the voltage or current amplitude of the currently applied AC signal and return to step 812.

[0281] Specifically, the process of combining the control of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the corresponding electrode piece 10 in step 811 to apply AC signals to each electrode unit 12 of the electrode piece is as follows:

[0282] Disconnect all grounding switches 25 electrically connected to the corresponding electrode piece 10, and simultaneously switch all bidirectional switching switches 26 electrically connected to the corresponding electrode piece 10 to the end that applies AC signals to each electrode unit 12; or

[0283] Disconnect all grounding switches 25 electrically connected to the corresponding electrode piece 10, and simultaneously switch all bidirectional switching switches 26 electrically connected to the corresponding electrode piece 10 to the end that connects each electrode unit 12 to the AC signal line 28; or

[0284] Disconnect all grounding switches 25 electrically connected to the corresponding electrode piece 10, and simultaneously switch all bidirectional switching switches 26 electrically connected to the corresponding electrode piece 10 to their respective input terminals 2.

[0285] The process of obtaining the temperature of each electrode unit 12 of the electrode sheet 10 in steps 812, 824, and 835 is specifically as follows:

[0286] Control the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch all of its input terminals 2 that apply AC signals to each electrode unit 12 to its acquisition terminals 1, and sequentially close the grounding switches 25 electrically connected to the electrode units 12 of the electrode sheet 10 to obtain the temperature of each electrode unit 12; or

[0287] Control the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch all of its input terminals 2 that apply AC signals to each electrode unit 12 to its acquisition terminals 1, and sequentially close the grounding switches 25 electrically connected to the electrode units 12 of the electrode sheet 10 to obtain the temperature of each electrode unit 12; or

[0288] Control the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch the electrode sheet 10 from its input terminals 2 that apply AC signals to each electrode unit 12 to its acquisition terminals 1, and sequentially close the grounding switches 25 electrically connected to the electrode units 12 of the electrode sheet 10 to obtain the temperature of each electrode unit 12; or

[0288] Control the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to switch the electrode sheet 10 from its input terminals 2 that apply AC signals to each electrode unit 12 to its acquisition terminals 1, and sequentially close the grounding switches 25 electrically connected to the electrode units 12 of the electrode sheet 10 to obtain the temperature of each electrode unit 12 of the electrode sheet 10. Signal line 28 is electrically connected to switch each electrode unit 12 to the corresponding analog-to-digital converter 23, and the grounding switch 25, which is electrically connected to each electrode unit 12 of the electrode plate 10, is closed sequentially in a time-division manner to obtain the temperature of each electrode unit 12 of the electrode plate 10; or

[0289] The bidirectional switching switch 26, which is electrically connected to the electrode plate 10, switches each electrode unit 12 of the electrode plate 10 from transmitting AC signals to transmitting DC signals or temperature detection signals. The grounding switch 25, which is electrically connected to each electrode unit 12 of the electrode plate 10, is closed sequentially in a time-sharing manner to obtain the temperature of each electrode unit 12 of the electrode plate 10.

[0290] The first preset temperature in steps 813, 825, 828, 836, and 838 is 40℃-40.3℃, preferably 40.2℃. In steps 815, 830, and 840, the second preset temperature is 40.4℃ to 40.6℃, preferably 40.5℃; in steps 817, 832, and 842, the third preset temperature is 40.7℃ to 40.9℃, preferably 40.8℃; in steps 819 and 844, the preset temperature threshold is 41℃ to 41.5℃, preferably 41℃; and in step 822, the preset quantity threshold is preferably 2.

[0291] The process of continuing to apply the AC signal as described in steps 814, 816, 818, 820, 829, 831, 833, 834, 839, 841, 843, and 845 is specifically as follows:

[0292] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied, and simultaneously control the bidirectional switching switch 26 electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied to conduct the AC signal transmission path electrically connected to the electrode unit 12 to which the AC signal needs to be continuously applied to continue applying the AC signal to the electrode unit 12; or

[0293] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 that needs to continue applying AC signals, and simultaneously control the bidirectional switching switch 26 electrically connected to the electrode unit 12 that needs to continue applying AC signals to switch from its respective acquisition terminal 1 to its respective input terminal 2, so as to continue applying AC signals to the electrode unit 12 that needs to continue applying AC signals; or

[0294] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 that needs to continue applying AC signals, and simultaneously control the bidirectional switching switch 26 electrically connected to the electrode unit 12 that needs to continue applying AC signals to electrically connect its respective input terminal 2 to the AC signal line 28, so as to continue applying AC signals to the electrode unit 12 that needs to continue applying AC signals; or

[0295] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 that needs to continue applying AC signals, and simultaneously control the bidirectional switching switch 26 electrically connected to the electrode unit 12 that needs to continue applying AC signals to close its respective input terminal 2. The acquisition terminal 1 is disconnected, thus continuing to apply an AC signal to the electrode unit 12 that requires continued AC signal application; or

[0296] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 that needs to continue applying AC signals, and simultaneously control the bidirectional switching switch 26 electrically connected to the electrode unit 12 that needs to continue applying AC signals so that the electrode unit 12 that needs to continue applying AC signals switches from transmitting temperature detection signals to applying AC signals.

[0297] The method of increasing the voltage or current amplitude of the currently applied AC signal in steps 814, 829, and 839 specifically refers to boosting the voltage of the currently applied AC signal by increasing the DC voltage amplitude by 0.03V per second before continuing to apply the AC signal.

[0298] The method of decreasing the voltage or current amplitude of the currently applied AC signal in steps 818, 820, 833, 834, 843, and 845 specifically refers to continuing to apply the AC signal by decreasing the voltage or current amplitude of the currently applied AC signal by 5V for 3 minutes.

[0299] The process of stopping the application of AC signals to each electrode unit 12 of the electrode plate 10 in step 823 specifically includes:

[0300] Controlling the bidirectional switching switch 26 electrically connected to the electrode plate 10 to disconnect the electrical connection between each electrode unit 12 of the electrode plate 10 and the AC signal line 28; or

[0301] Controlling the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch all of its ends that apply AC signals to each electrode unit 12 to its ends that collect temperature data from each electrode unit 12; or

[0302] Controlling the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch all of its input ends 2 that apply AC signals to each electrode unit 12 to its acquisition ends 1; or

[0303] Controlling the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch the electrode plate 10 from an electrical connection between each electrode unit 12 and the AC signal line 28 to an electrical connection between each electrode unit 12 and the corresponding analog-to-digital converter 23; or

[0304] The bidirectional switching switch 26, electrically connected to the electrode plate 10, switches each electrode unit 12 of the electrode plate 10 from transmitting AC signals to transmitting DC signals or temperature detection signals. (Instruction manual, pages 41 / 43, CN 121288195 A)

[0305] The process of stopping the application of AC signals to each electrode unit 12 in the over-temperature region as described in step 827 specifically involves:

[0306] Controlling the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature region to disconnect the electrical connection between each electrode unit 12 in the over-temperature region and the AC signal line 28; or

[0307] Controlling the bidirectional switching switch 26 electrically connected to each electrode unit 12 in the over-temperature region to switch all its ends from the end that applies AC signals to each electrode unit 12 in the over-temperature region to the end that performs temperature acquisition; or

[0308] The bidirectional switching switch 26, which controls the electrical connection of each electrode unit 12 in the over-temperature zone, switches all input terminals 2 that apply AC signals to each electrode unit 12 in the over-temperature zone to its acquisition terminal 1; or

[0309] the bidirectional switching switch 26, which controls the electrical connection of each electrode unit 12 in the over-temperature zone, switches each electrode unit 12 in the over-temperature zone from being electrically connected to the AC signal line 28 to being electrically connected to the corresponding analog-to-digital converter 23; or

[0310] the bidirectional switching switch 26, which controls the electrical connection of each electrode unit 12 in the over-temperature zone, switches each electrode unit 12 in the over-temperature zone from transmitting AC signals to transmitting DC signals or temperature detection signals.

[0311] When the tumor electric field therapy system 100 is in the standby state before starting work, no AC signal is applied to the electrode unit 12. The first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls the bidirectional switching switch 26 to switch to the acquisition terminal 1. The grounding switch 25 is turned on in sequence. The analog-to-digital converter 23 receives the temperature detection signal of the temperature sensor 14 corresponding to each row of electrode units 12 in sequence.

[0312] When the first grounding switch 25-1 is on, all other grounding switches 25 are off, and all bidirectional switching switches 26 are placed at the acquisition terminal 1, the analog-to-digital converter 23 receives the temperature detection signal of the temperature sensor 14 corresponding to the electrode unit 12;

[0313] When the second grounding switch 25-2 is on, all other grounding switches 25 are off, and all bidirectional switching switches 26 are placed at the acquisition terminal 1, the analog-to-digital converter 23 receives the temperature detection signal of the temperature sensor 14 corresponding to the electrode unit 12;

[0314] When the third grounding switch 25-3 is on, all other grounding switches 25 are off, and all bidirectional switching switches 26 are placed at the acquisition terminal 1, the analog-to-digital converter 23 receives the temperature detection signal of the temperature sensor 14 corresponding to the electrode unit 12;

[0315] When the fourth grounding switch 25-4 is on, all other grounding switches 25 are off, and all bidirectional switching switches 26 are placed at the acquisition terminal 1, the analog-to-digital converter 23 receives the temperature detection signal of the temperature sensor 14 corresponding to the electrode unit 12.

[0316] The first controller 22 receives the temperature detection signals from the temperature sensors 14 corresponding to each electrode unit 12 via the analog-to-digital converter 23, and transmits them to the AC signal generator 34 of the electric field generator 30 via the first communication unit 27 and the second communication unit 33. The second controller 32 then controls or adjusts the AC signals applied to each electrode unit 12.

[0317] Although the various operations are depicted in the drawings in a specific order, this should not be construed as requiring these operations to be performed in the specific order shown or in chronological order, nor should it be construed as requiring all shown operations to be performed to obtain the desired result.

[0318] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this application, and are not intended to limit them;While the foregoing embodiments have provided a detailed description of this application, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features. These modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions in the embodiments of this application, and all should be covered within the scope of the claims and specification of this application. In particular, as long as there is no structural conflict, the various technical features mentioned in the embodiments can be combined in any way. This application is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims.

[0319] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this application, and not to limit them; although the present application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein; and these modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this application, and they should all be covered within the scope of the claims and the specification of this application. In particular, as long as there is no structural conflict, the various technical features mentioned in the various embodiments can be combined in any way. This application is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims. Instruction manual page 43 / 43, page 47, CN 121288195 A, Figure 1; Instruction manual figure 1 / 27, page 48, CN 121288195 A, Figure 2; Instruction manual figure 2 / 27, page 49, CN 121288195 A, Figure 3; Instruction manual figure 3 / 27, page 50, CN 121288195 A, Figure 4; Instruction manual figure 4 / 27, page 51, CN 121288195 A, Figure 5; Instruction manual figure 5 / 27, page 52, CN 121288195 A, Figure 6; Instruction manual figure 6 / 27, page 53, CN 121288195 A, Figure 7; Instruction manual figure 7 / 27, page 54, CN 121288195 A, Figure 8; Instruction manual figure 8 / 27, page 55, CN 121288195 A, Figure 9; Instruction manual figure 9 / 27, page 56, CN 121288195 A, Figure 10. Instruction manual, figures 10 / 27, page 57, CN 121288195 A, Figure 11(A), Figure 11(B); Instruction manual, figures 11 / 27, page 58, CNFigure 12 (Instruction Manual Appendix), page 59, 121288195 A; Figure 13 (Instruction Manual Appendix), page 60, 13 / 27; Figure 14 (Instruction Manual Appendix), page 61, 14 / 27; Figure 15 (Instruction Manual Appendix), page 62, 15 / 27; Figure 16 (Instruction Manual Appendix), page 63, 16 / 27; Figure 17 (Instruction Manual Appendix), page 64, 17 / 27; Figure 18 (Instruction Manual Appendix), page 65, 19 (Instruction Manual Appendix), page 66, 19 / 27; Figure 20 (Instruction Manual Appendix), page 67, 121288195 A Figure 21 Appendix to the Instruction Manual, Page 21 / 27, 68 CN 121288195 A Figure 22 Appendix to the Instruction Manual, Page 22 / 27, 69 CN 121288195 A Figure 23 Figure 24 Appendix to the Instruction Manual, Page 23 / 27, 70 CN 121288195 A Figure 25 Figure 26 Appendix to the Instruction Manual, Page 24 / 27, 71 CN 121288195 A Figure 27 Appendix to the Instruction Manual, Page 25 / 27, 72 CN 121288195 A Figure 28 Appendix to the Instruction Manual, Page 26 / 27, 73 CN 121288195 A Figure 29 Appendix to the Instruction Manual, Page 27 / 27, 74 CN 121288195 A Abstract The present invention provides a tumor electric field therapy system, a method for detecting temperatures and over-temperatures of electrode pads. The system comprises electrode pads and a controller. The electrode pad comprises a flexible circuit board and a plurality of electrode units disposed on the flexible circuit board andarranged in a circuit with a plurality of rows and columns, each electrode unit is provided with a dielectric element and a temperature sensor, the flexible circuit board is provided with a plurality of grounding lines and a plurality of dual- purpose signal lines, each grounding line is respectively short-circuited with the grounding terminal of each temperature sensor in a corresponding row, and each dual-purpose signal line is respectively connected with the dielectric element of each electrode unit and the signal terminal of the temperature sensor of each electrode unit in a corresponding column. The controller controls the dual-purpose signal line electrically connected with a target electrode unit to selectively switch between connection to an alternating current signal and a direct current signal, thereby applying the alternating current signals to the target electrode unit or collecting the temperature of the target electrode unit.

Claims

1. A tumor electric field therapy system, characterized in that: It includes: An electrode sheet includes a flexible circuit board having multiple grounding wires and multiple dual-purpose signal lines therein, and multiple electrode units disposed on the flexible circuit board. Each electrode unit has a dielectric element for applying an AC signal and a temperature sensor for detecting temperature, having a ground terminal and a signal terminal. The signal terminal of the temperature sensor of the electrode unit is short-circuited with its dielectric element. The plurality of electrode units are configured in the circuit as multiple row groups and multiple column groups, wherein the ground terminals of the temperature sensors of each electrode unit located in the same row group are all short-circuited through the same grounding line, and the ground terminals of the temperature sensors of each electrode unit located in different row groups are respectively connected in parallel through different grounding lines; the dielectric element and the signal terminal of the temperature sensor of each electrode unit located in the same column group are all short-circuited through the same dual-purpose signal line, and the dielectric element and the signal terminal of the temperature sensor of each electrode unit located in different column groups are respectively connected in parallel through different dual-purpose signal lines; and The controller is configured to: (1) determine the area where a target electrode unit is located that requires the application of an AC signal or the acquisition of temperature; (2) control the dual-purpose signal line electrically connected to the area to be in a first mode to transmit an AC signal to the target electrode unit; and (3) control the dual-purpose signal line electrically connected to the area to be in a second mode to transmit a DC signal to the target electrode unit to acquire the temperature of the target electrode unit; wherein the target electrode unit applies an AC signal through its dielectric element in the first mode and detects or acquires temperature through its temperature sensor in the second mode.

2. The tumor electric field therapy system according to claim 1, characterized in that, Multiple bidirectional switching switches are provided, and each dual-purpose signal line is connected in series with a corresponding bidirectional switching switch. The bidirectional switching switch has an input terminal for receiving AC signals and a acquisition terminal for receiving DC signals. The controller is configured to: control the bidirectional switching switch to conduct its input terminal in a first mode so that the dual-purpose signal line is connected to AC signals, and conduct its acquisition terminal in a second mode so that the dual-purpose signal line is connected to DC signals.

3. The tumor electric field therapy system according to claim 2, characterized in that, Multiple grounding switches are provided, and each grounding wire is connected in series with a corresponding grounding switch and grounded through the corresponding grounding switch. The controller is configured to: control all the grounding switches to be disconnected in a first mode, and sequentially turn on each grounding wire in a second mode to collect the temperature detection signals detected by each temperature sensor row by row.

4. The tumor electric field therapy system according to claim 3, characterized in that, When performing temperature detection on a target electrode unit, the bidirectional switching switch connected to the dual-purpose signal line corresponding to the column group where the target electrode unit is located is turned on separately to receive a DC signal, and at the same time, the grounding switch connected to the grounding line corresponding to the row group where the target electrode unit is located is turned on separately.

5. The tumor electric field therapy system according to claim 2, characterized in that, An analog-to-digital converter is provided, which has multiple detection channels. The acquisition terminal of each bidirectional switching switch is electrically connected to a corresponding detection channel. The analog-to-digital converter samples the temperature detection signals of each temperature sensor.

6. The tumor electric field therapy system according to claim 2, characterized in that, An AC signal line is provided, and the input terminal of each of the bidirectional switching switches is electrically connected to the AC signal line.

7. The tumor electric field therapy system according to claim 1, characterized in that, The electrode unit also has a third mode in which the electrode unit stops applying AC signals and stops detecting or acquiring temperature.

8. The tumor electric field therapy system according to claim 1, characterized in that, The controller is also configured to determine the operating state of each electrode unit based on the temperature detection signals of each of the temperature sensors.

9. The tumor electric field therapy system according to claim 8, characterized in that, The controller has a preset temperature threshold and is configured to: Compare the temperature detection signals of each of the temperature sensors with the preset temperature threshold; The operating mode of each dual-purpose signal line is determined based on the comparison results.

10. The tumor electric field therapy system according to claim 9, characterized in that, The controller is configured to: When all the temperature detection signals are less than the preset temperature threshold, the combination control of each grounding switch and each bidirectional switching switch enables each dual-purpose signal line to continue transmitting AC signals to the dielectric element of each electrode unit. When a temperature detection signal exceeds the preset temperature threshold, the grounding switch and the bidirectional switching switch are controlled in combination to stop all dual-purpose signal lines from transmitting AC signals to the dielectric elements of the electrode units; or the dual-purpose signal lines corresponding to the column group of the electrode unit that exceeds the preset temperature threshold stop transmitting AC signals to the dielectric elements of the electrode units in that column group, while the remaining dual-purpose signal lines continue to transmit AC signals to the dielectric elements of the electrode units in their corresponding columns.

11. The tumor electric field therapy system according to claim 9, characterized in that, The controller is configured to: When the temperature detection signal of each of the temperature sensors is much lower than the preset temperature threshold, each of the dual-purpose signal lines is controlled to increase the strength of the currently transmitted AC signal or to continue transmitting the AC signal to the dielectric element of each of the electrode units in a manner that maintains the strength of the currently transmitted AC signal unchanged. When the temperature detection signal of at least one of the temperature sensors approaches the preset temperature threshold, each of the dual-purpose signal lines is controlled to continue transmitting the AC signal to the dielectric element of each of the electrode units in a manner that either maintains the strength of the currently transmitted AC signal or reduces the strength of the currently transmitted AC signal. When the temperature detection signal of at least one of the temperature sensors exceeds the preset temperature threshold, the dual-purpose signal line is controlled to stop transmitting the AC signal to the dielectric element of each of the electrode units; or the dual-purpose signal line corresponding to the electrode unit whose temperature detection signal exceeds the preset temperature threshold is controlled to stop transmitting the AC signal to the dielectric element of each of the electrode units in its corresponding column group, and the remaining dual-purpose signal lines are controlled to continue transmitting the AC signal to the dielectric element of each of the electrode units in their corresponding column group.

12. The tumor electric field therapy system according to claim 9, characterized in that, The controller has a first preset temperature lower than the preset temperature threshold, and the controller is configured to: When the temperature detection signals of each of the temperature sensors are all lower than the first preset temperature, control each of the dual-purpose signal lines to increase the strength of the currently transmitted AC signal and continue to transmit the AC signal to the dielectric element of each of the electrode units. When the temperature detection signals of all the temperature sensors are less than the preset temperature threshold and the temperature detection signal of at least one of the temperature sensors exceeds the first preset temperature, the dual-purpose signal lines are controlled to continue transmitting the AC signal to the dielectric element of each electrode unit in a manner that either keeps the strength of the currently transmitted AC signal unchanged or reduces the strength of the currently transmitted AC signal. When the temperature detection signal of at least one of the temperature sensors exceeds the preset temperature threshold, control each of the dual-purpose signal lines to stop transmitting the AC signal to the dielectric element of each of the electrode units; or control the dual-purpose signal line corresponding to the electrode unit whose temperature detection signal exceeds the preset temperature threshold to stop transmitting the AC signal to the dielectric element of each of the electrode units in its corresponding column group and control the remaining dual-purpose signal lines to continue transmitting the AC signal to the dielectric element of each of the electrode units in their corresponding column group.

13. A method for detecting the temperature of an electrode sheet, characterized in that, The method, applied to the tumor electric field therapy system as described in any one of claims 1 to 12, comprises: The dual-purpose signal lines are disconnected from the AC signal to stop applying the AC signal to the dielectric element of each electrode unit, while a DC signal is connected to transmit the DC signal to the signal terminal of the temperature sensor of each electrode unit. Each of the grounding wires is controlled to be grounded individually in sequence to obtain the temperature detection signal of the temperature sensor of each of the electrode units.

14. The method according to claim 13, characterized in that, Based on the temperature detection signals of each temperature sensor of the electrode sheet, at least one of the following judgments is made: (1) whether the temperature sensor of the electrode sheet is faulty or abnormal; (2) whether the electrode sheet is qualified; (3) whether the electrode sheet needs to be replaced; (4) if the electrode sheet is qualified, identify the type of the electrode sheet; (5) if the electrode sheet is qualified, determine whether the electrode unit of the electrode sheet is over-temperature.

15. A method for detecting overheating of an electrode sheet, characterized in that: The method, applied to the tumor electric field therapy system as described in any one of claims 1-12, comprises: The combined control of each of the grounding switches and each of the bidirectional switching switches is used to cause each of the electrode units to enter a first mode in which an AC signal is applied through its dielectric element; The combined control of each of the grounding switches and each of the bidirectional switching switches enables each of the electrode units to enter a second mode by detecting or acquiring the temperature of each of the electrode units through their temperature sensors; The temperature of each electrode unit is compared with a preset temperature threshold, and the working state of each electrode unit is determined based on the comparison result.

16. The method according to claim 15, characterized in that, When there are electrode units on the electrode sheet with a temperature greater than the preset temperature threshold, the dual-purpose signal line is configured to stop transmitting the AC signal to each of the electrode units.

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