Composition for use
Patent Information
- Application Number
- HK62026125310
- Authority / Receiving Office
- HK · HK
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2023-03-30
- Filing Date
- 2026-06-25
- Publication Date
- 2026-09-18
- Estimated Expiration
- 2044-03-27
Smart Images
Figure 00000035_0000 
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Abstract
Description
Abstract This invention provides a method for identifying infants or young children at risk of growth retardation, and a composition for preventing and / or treating growth retardation in infants or young children.
Claims
CLAIMS1 . A method for identifying an infant or young child at risk of stunted growth, wherein said method comprises determining the abundance of Bifidobacterium pseudocatenulatum and / or Streptococcus thermophilus in one or more samples obtained from the infant.
2. The method according to claim 1 , wherein an infant or young child with reduced levels of B. pseudocatenulatum is identified as at risk of stunted growth.
3. The method according to any preceding claim wherein the stunted growth is stunted height or length; optionally wherein the stunted height or length is defined as a reduced length- for-age z-score (LAZ) or a reduced LAZ over time or a reduced height-for-age z-score (HAZ) or a reduced HAZ over time.
4. A composition for use in preventing and / or treating stunted growth in an infant or young child, wherein the composition promotes B. pseudocatenulatum and / or Streptococcus thermophilus in the gut microbiota of the infant or young child.
5. The composition for use according to claim 4, wherein the composition promotes B. pseudocatenulatum in the gut microbiota of the infant or young child; optionally wherein the composition comprises a B. pseudocatenulatum microorganism.
6. The composition for use according to claim 4, wherein the composition comprises a prebiotic.
7. A combination of a B. pseudocatenulatum and / or Streptococcus thermophilus microorganism and a prebiotic for use in preventing and / or treating stunted growth in an infant or young child.
8. The composition or combination for use according to any claim 6 or 7, wherein the prebiotic is in the form of a dietary or nutritional composition.
9. The composition or combination for use according to claim 8 wherein the prebiotic comprises a human milk oligosaccharide (HMO).
10. A human milk oligosaccharide (HMO) or a combination of HMOs for use in preventing and / or treating stunted growth in an infant or young child, wherein the HMO or combination of HMOs promote B. pseudocatenulatum and / or Streptococcus thermophilus in the gut microbiota of the infant or young child.1 1. A B. pseudocatenulatum and / or Streptococcus thermophilus microorganism for use in preventing and / or treating stunted growth in an infant or young child.
12. The composition, combination, HMO or B. pseudocatenulatum and / or Streptococcus thermophilus microorganism for use according to any of claims 4 to 11 wherein the infant or young child has been determined to be at risk of stunted growth by the method of any of claims 1 to 3.
13. The composition, combination, HMO or B. pseudocatenulatum and / or Streptococcus thermophilus microorganism for use according to any of claims 4 to 12 wherein the stunted growth is stunted height or length; optionally wherein the stunted height or length is defined as a reduced length-for-age z-score (LAZ) or a reduced LAZ over time or a reduced height- for-age z-score (HAZ) or a reduced HAZ over time.
14. The composition, combination, HMO or B. pseudocatenulatum and / or Streptococcus thermophilus microorganism for use according to any of claims 4 to 13 wherein bone development and / or bone strength is enhanced in the subject.
15. A synbiotic composition comprising B. pseudocatenulatum and / or Streptococcus thermophilus and a prebiotic wherein the prebiotic is a HMO which promotes B. pseudocatenulatum and / or Streptococcus thermophilus in the gut microbiota of an infant or young child.