Compositions and methods for cancer immunotherapy

IL286792BActive Publication Date: 2026-08-01HOUN SIMON HSIA
0 Cites 0 Cited by

Patent Information

Application Number
IL286792
Authority / Receiving Office
IL · IL
Patent Type
Patents
Current Assignee / Owner
Priority Date
2019-09-03
Filing Date
2020-03-31
Publication Date
2026-08-01
Estimated Expiration
2040-03-31

AI Technical Summary

Technical Problem

Current cancer immunotherapies, including antibody-based, cytokine-based, and cell-based approaches, are associated with significant side effects and variable efficacy, necessitating a more tolerable and effective immunotherapeutic method for treating cancer, particularly drug-resistant forms.

Method used

A nutritional supplement comprising selenium and fish oil, which modulates the expression of immune checkpoint proteins, angiogenesis-related proteins, and metastasis-associated proteins in cancer cells, potentially used alone or in combination with chemotherapy and radiotherapy, to enhance anti-tumor immune responses.

Benefits of technology

The supplement effectively reduces expression of proteins like PD-L1, AXL, and HSP90, increases anti-tumor immune cell populations, and synergizes with chemotherapeutic agents to improve treatment outcomes, offering a well-tolerated and effective immunotherapeutic approach.

✦ Generated by Eureka AI based on patent content.
Patent Text Reader

Abstract

Compositions and methods are described in which a nutritional supplement (such as a supplement that includes chromium and certain plant-derived materials and / or a supplement that includes a selenium yeast peptide complex and fish oil is used to provide an immunotherapeutic effect, which can be demonstrated by modulation of cell-surface markers targeted by conventional immunotherapeutic drugs. The nutritional supplements can be used in combination with other antineoplastic therapies, such as radiation and / or chemotherapeutic agents. Such combination therapy can provide a synergistic effect in regard to modulation of cell surface markers that serve as immunotherapy targets.
Need to check novelty before this filing date? Find Prior Art